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https://www.readbyqxmd.com/read/29345913/non-centrosymmetric-rbnamgp2o7-with-unprecedented-thermo-induced-enhancement-of-second-harmonic-generation
#1
Sangen Zhao, Xiaoyan Yang, Yi Yang, Xiaojun Kuang, Fengqi Lu, Pai Shan, Zhihua Sun, Zheshuai Lin, Maochun Hong, Junhua Luo
It is of great difficulty to obtain deep-UV transparent materials with enhanced second harmonic generation (SHG), mainly limited by the theoretically poor transparency of these materials in the deep-UV spectral region. Here we report a new non-centrosymmetric, deep-UV transparent phosphate RbNaMgP2O7, which undergoes a thermo-induced reversible phase transition (at a high temperature of 723 K) and correspondingly an evident SHG enhancement up to ~1.5 times. The phase transition is aroused by the twist of [P2O7]4- dimers with deviation from the P-O-P equilibrium positions...
January 18, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29345039/successful-treatment-in-a-case-of-ultra-rapid-cycling-bipolar-disorder-is-reflected-in-brain-arousal-regulation
#2
Christine Ulke, Nicole Mauche, Christian Makiol, Klara Bednasch, Dirk A Wittekind, Ulrich Hegerl, Maria Strauß
No abstract text is available yet for this article.
January 18, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29344649/effects-of-intrathecal-bupivacaine-on-the-nr2b-camkii%C3%AE-creb-signaling-pathway-in-the-rat-lumbar-spinal-cord
#3
Liyan Zhao, Yonghai Zhang, Fan Yang, Di Zhu, Ningkang Li, Li Zhao, Na Li, Jianqiang Yu, Hanxiang Ma
Neuraxial anesthesia produces an anesthetic-sparing, sedative effect. The mechanism underlying this effect potentially involves decreased spinal afferent input. However, the neurochemical mechanisms at the spinal level remain unknown. The N‑methyl‑D‑aspartate receptor 2B subunit/calcium‑calmodulin‑dependent protein kinase II α/cAMP response element‑binding protein (NR2B/CaMKIIα/CREB) signaling pathway serves an important role in regulating the transmittance of peripheral noxious stimulation to supraspinal regions in the process of nociception...
January 17, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29343686/human-brain-patterns-underlying-vigilant-attention-impact-of-sleep-debt-circadian-phase-and-attentional-engagement
#4
M Maire, C F Reichert, V Gabel, A U Viola, C Phillips, C Berthomier, S Borgwardt, C Cajochen, C Schmidt
Sleepiness and cognitive function vary over the 24-h day due to circadian and sleep-wake-dependent mechanisms. However, the underlying cerebral hallmarks associated with these variations remain to be fully established. Using functional magnetic resonance imaging (fMRI), we investigated brain responses associated with circadian and homeostatic sleep-wake-driven dynamics of subjective sleepiness throughout day and night. Healthy volunteers regularly performed a psychomotor vigilance task (PVT) in the MR-scanner during a 40-h sleep deprivation (high sleep pressure) and a 40-h multiple nap protocol (low sleep pressure)...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342958/an-enhanced-method-to-estimate-heart-rate-from-seismocardiography-via-ensemble-averaging-of-body-movements-at-six-degrees-of-freedom
#5
Hyunwoo Lee, Hana Lee, Mincheol Whang
Continuous cardiac monitoring has been developed to evaluate cardiac activity outside of clinical environments due to the advancement of novel instruments. Seismocardiography (SCG) is one of the vital components that could develop such a monitoring system. Although SCG has been presented with a lower accuracy, this novel cardiac indicator has been steadily proposed over traditional methods such as electrocardiography (ECG). Thus, it is necessary to develop an enhanced method by combining the significant cardiac indicators...
January 15, 2018: Sensors
https://www.readbyqxmd.com/read/29341884/acute-stress-persistently-alters-locus-coeruleus-function-and-anxiety-like-behavior-in-adolescent-rats
#6
Olga Borodovitsyna, Matthew D Flamini, Daniel J Chandler
Stress is a physiological state characterized by altered neuroendocrine signaling, behavioral arousal, and anxiety. Chronic or traumatic stress may predispose individuals for multiple somatic and psychiatric illnesses. The locus coeruleus (LC) is a major node in the stress response that integrates input from multiple stress responsive neural circuits and releases norepinephrine throughout the central nervous system to promote vigilance and anxiety. Many mood disorders associated with prior stress are characterized by chronically altered noradrenergic signaling, yet the long-term impact of an acute stressor on LC function is not clear...
January 13, 2018: Neuroscience
https://www.readbyqxmd.com/read/29341401/the-prediction-probabilities-for-emergence-from-sevoflurane-anesthesia-in-children-a-comparison-of-the-perfusion-index-and-the-bispectral-index
#7
Pei-Pei Liu, Chi Wu, Jun-Zheng Wu, Ma-Zhong Zhang, Ji-Jian Zheng, Yang Shen, Pan He, Ying Sun
BACKGROUND: Predicting recovery of consciousness is one of the most essential functions of anesthesia depth monitors in anesthesia practice. Perfusion index and bispectral index are 2 indicators of the anesthesia depth monitoring with different working principles. The progression of the anesthesia emergence stages reflected by those monitors has not been well understood, especially in pediatric patients. The goals of this study were to compare the prediction probabilities of perfusion index and bispectral index in predicting awakening and in differentiating the different levels of arousal during emergence after sevoflurane anesthesia in children undergoing open inguinal hernia repairs...
January 17, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29341236/induced-earthquakes-from-long-term-gas-extraction-in-groningen-the-netherlands-statistical-analysis-and-prognosis-for-acceptable-risk-regulation
#8
Charles Vlek
Recently, growing earthquake activity in the northeastern Netherlands has aroused considerable concern among the 600,000 provincial inhabitants. There, at 3 km deep, the rich Groningen gas field extends over 900 km2 and still contains about 600 of the original 2,800 billion cubic meters (bcm). Particularly after 2001, earthquakes have increased in number, magnitude (M, on the logarithmic Richter scale), and damage to numerous buildings. The man-made nature of extraction-induced earthquakes challenges static notions of risk, complicates formal risk assessment, and questions familiar conceptions of acceptable risk...
January 16, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29340968/a-novel-blink-detection-method-based-on-pupillometry-noise
#9
Ronen Hershman, Avishai Henik, Noga Cohen
Pupillometry (or the measurement of pupil size) is commonly used as an index of cognitive load and arousal. Pupil size data are recorded using eyetracking devices that provide an output containing pupil size at various points in time. During blinks the eyetracking device loses track of the pupil, resulting in missing values in the output file. The missing-sample time window is preceded and followed by a sharp change in the recorded pupil size, due to the opening and closing of the eyelids. This eyelid signal can create artificial effects if it is not removed from the data...
January 16, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29340251/the-relationships-between-exercise-and-affective-states-a-naturalistic-longitudinal-study-of-recreational-runners
#10
Tim Bonham, Gillian V Pepper, Daniel Nettle
Background: Although people generally feel more positive and more energetic in the aftermath of exercise than before, longitudinal research on how exercise relates to within-person fluctuations in affect over the course of everyday life is still relatively limited. One constraint on doing such research is the need to provide participants with accelerometers to objectively record their exercise, and pagers to capture affective reports. Aims: We aimed to develop a methodology for studying affect and exercise using only technology that participants already possess, namely GPS running watches and smartphones...
2018: PeerJ
https://www.readbyqxmd.com/read/29339304/transformation-products-formation-of-ciprofloxacin-in-uva-led-and-uva-led-tio2-systems-impact-of-natural-organic-matter-characteristics
#11
Si Li, Jiangyong Hu
The role of natural organic matter (NOM) in contaminants removal by photolysis and photocatalysis has aroused increasing interest. However, evaluation of the influence of NOM characteristics on the transformation products (TPs) formation and transformation pathways of contaminants has rarely been performed. This study investigated the decomposition kinetics, mineralization, TPs formation and transformation pathways of antibiotic ciprofloxacin (CIP) during photolysis and photocatalysis in the presence of three commercial NOM isolates (Sigma-Aldrich humic acid (SAHA), Suwannee River humic acid (SRHA) and Suwannee River NOM (SRNOM)) by using UVA light emitting diode (UVA/LED) as an alternative light source...
January 9, 2018: Water Research
https://www.readbyqxmd.com/read/29339250/discovery-of-novel-hsp90-inhibitors-that-induced-apoptosis-and-impaired-autophagic-flux-in-a549-lung-cancer-cells
#12
Qun Wei, Jun-Ya Ning, Xi Dai, Yuan-Di Gao, Le Su, Bao-Xiang Zhao, Jun-Ying Miao
Heat shock protein 90 (HSP90) inhibition has aroused increasing enthusiasm in antitumor strategies in recent years. According to our previous studies, we synthesized a series of coumarin pyrazoline compounds HCP1-HCP6 that might be HSP90 inhibitors. Interactions between HCP1-HCP6 and HSP90 were examined and antitumor activities of them were investigated in A549 lung cancer cells. Results showed that all the six derivatives could interact with HSP90, in which HCP1 exhibited the best binding ability and inhibited the activity of HSP90...
January 10, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29339116/understanding-women-s-subjective-sexual-arousal-within-the-laboratory-definition-measurement-and-manipulation
#13
REVIEW
Ariel B Handy, Amelia M Stanton, Cindy M Meston
INTRODUCTION: Subjective sexual arousal (SSA) is positive, cognitive engagement in sexual activity. SSA is considered an important aspect of the sexual experience, as it has been found to facilitate sexual activity and, in situations of chronically low or absent arousal, potentially cause distress. Despite the clinical implications of SSA, a thorough review of how to manipulate SSA has yet to be conducted. AIM: To review the state of knowledge about SSA in women, including its definition, measurement, and the outcomes of studies attempting to manipulate SSA within a laboratory setting...
January 12, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29338486/rewarding-effects-of-physical-activity-predict-sensitivity-to-the-acute-subjective-effects-of-d-amphetamine-in-healthy-volunteers
#14
Mollie S Pester, Matthew G Kirkpatrick, Bree A Geary, Adam M Leventhal
While individual differences in reward sensitivity are believed to generalize across drugs and alternative rewards, this notion has received little empirical attention in human research. Here, we tested whether individual differences in the subjective rewarding effects of physical activity were associated with the subjective response to d-amphetamine administration. Healthy volunteers ( n=95; age 18-35 years) completed questionnaires measuring the self-reported pleasurable effects of physical activity and other covariates, and this was followed by two double-blind counterbalanced sessions during which they received either 20 mg oral d-amphetamine or placebo...
January 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29338192/under-oil-switchable-superhydrophobicity-to-superhydrophilicity-transition-on-tio2-nanotube-arrays
#15
Hongjun Kang, Yuyan Liu, Hua Lai, Xiaoyan Yu, Zhongjun Cheng, Lei Jiang
Recently, smart interfacial materials that can reversibly transit between the superhydrophobicity and superhydrophilicity have aroused much attention. However, all present performances happen in air, and to realize such a smart transition in complex environments, such as oil, is still a challenge. Herein, TiO2 nanotube arrays with switchable transition between the superhydrophobicity and superhydrophilicity in oil are reported. The switching can be observed by alternation of UV irradiation and heating process, and the smart controllability can be ascribed to the cooperative effect between the surface nanostructures and the chemical composition variation...
January 17, 2018: ACS Nano
https://www.readbyqxmd.com/read/29337408/maternally-expressed-mir-379-mir-544-cluster-is-dispensable-for-testicular-development-and-spermatogenesis-in-mice
#16
Congcong Cao, Yujiao Wen, Juan Dong, Xiaoli Wang, Weibing Qin, Xunbin Huang, Shuiqiao Yuan
Increasing lines of evidence suggest that miRNAs are closely related to spermatogenesis and male infertility which has aroused widespread concerns.The miR-379/miR-544 locus is the largest known placental mammal-specific miRNA cluster, whose 24 miRNA genes are expressed only from the maternal allele, and located within the high conservation of the imprinted Dlk1â€"Dio3 region.A correct dosage of imprinted genes encoded at the mouse Dlk1-Dio3 genomic interval is essential for embryonic growth and postnatal survival, as well as for muscle growth, skeletal, and neuronal development...
January 16, 2018: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/29334821/development-and-validation-of-a-facial-expression-database-based-on-the-dimensional-and-categorical-model-of-emotions
#17
Tomomi Fujimura, Hiroyuki Umemura
The present study describes the development and validation of a facial expression database comprising five different horizontal face angles in dynamic and static presentations. The database includes twelve expression types portrayed by eight Japanese models. This database was inspired by the dimensional and categorical model of emotions: surprise, fear, sadness, anger with open mouth, anger with closed mouth, disgust with open mouth, disgust with closed mouth, excitement, happiness, relaxation, sleepiness, and neutral (static only)...
January 15, 2018: Cognition & Emotion
https://www.readbyqxmd.com/read/29334641/do-clinically-anxious-children-cluster-according-to-their-expression-of-factors-that-maintain-child-anxiety
#18
Samantha Pearcey, Anna Alkozei, Bhismadev Chakrabarti, Helen Dodd, Kou Murayama, Suzannah Stuijfzand, Cathy Creswell
BACKGROUND: Cognitive Behaviour Therapy (CBT) is an effective treatment for childhood anxiety disorders, yet a significant proportion of children do not benefit from it. CBT for child anxiety disorders typically includes a range of strategies that may not all be applicable for all affected children. This study explored whether there are distinct subgroups of children with anxiety disorders who are characterized by their responses to measures of the key mechanisms that are targeted in CBT (i...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29334095/gd3-doped-mose2-nanosheets-used-as-a-theranostic-agent-for-bimodal-imaging-and-highly-efficient-photothermal-cancer-therapy
#19
Jiali Pan, Xufeng Zhu, Xu Chen, Yingyu Zhao, Jie Liu
Recently, two dimensional transition metal dichalcogenides (TMDCs) being used as nanomedicine have aroused great interest because of their unique photothermal properties. A simple liquid-phase method was used to prepare gadolinium (Gd3+)-doped molybdenum selenide (MoSe2) nanosheets, and then using poly(ethylene glycol) (PEG) modification on the surface, MoSe2(Gd3+)-PEG nanosheets were obtained which had high stability in physiological solutions and showed no obvious toxicity in vivo. It revealed that Gd3+ used as a paramagnetic material for MoSe2(Gd3+)-PEG provided a strong contrast effect in magnetic resonance imaging, furthermore, the MoSe2 showed strong absorption in the near infrared region, and therefore, MoSe2(Gd3+)-PEG could be used as contrast agent for photoacoustic imaging (PAI)...
January 15, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29332591/anti-trypanosoma-cruzi-activity-in-vitro-of-phases-and-isolated-compounds-from-excoecaria-lucida-leaves
#20
Cristiane Franca da Silva, Ania Ochoa Pacheco, Rayane Nogueira Alves, Josean Fechine Tavares, Marcelo Sobral da Silva, Julio Cesar Escalona Arranz
BACKGROUND: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. This illness is found mainly in 21 Latin American countries and an estimated 8 million people are infected worldwide. The unsatisfactory chemotherapy provokes severe toxicity and resistant strains. Medicinal plants constitute a promising source of new drugs and remedies against all kinds of disorders, mainly infectious diseases arousing interest worldwide. OBJECTIVE: The aim of this study has been the isolation, structural identification and evaluation of the trypanocidal activity of samples present in the Excoecaria lucida Sw...
January 11, 2018: Medicinal Chemistry
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