keyword
MENU ▼
Read by QxMD icon Read
search

Cardiac strain

keyword
https://www.readbyqxmd.com/read/29339687/subclinical-left-ventricular-systolic-dysfunction-in-patients-with-severe-aortic-stenosis-a-speckle-tracking-echocardiography-study
#1
Betül Cengiz, Şükrü Taylan Şahin, Selen Yurdakul, Serkan Kahraman, Ayşen Bozkurt, Saide Aytekin
OBJECTIVE: In patients with aortic stenosis (AS), the left ventricular (LV) geometry changes due to the increased LV afterload. However, subclinical myocardial dysfunction can develop despite a normal LV ejection fraction (EF). This study was an investigation of subclinical LV systolic dysfunction in patients with severe AS with a normal LV EF using a strain imaging method, speckle-tracking echocardiography (STE), and an evaluation of its correlation with novel indices to assess the severity of AS...
January 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29339401/the-impact-of-preload-reduction-with-head-up-tilt-testing-on-longitudinal-and-transverse-left-ventricular-mechanics-a-study-utilizing-deformation-volume-analysis
#2
Caroline Schneider, Lynsey Forsythe, John Somauroo, Keith George, David Oxborough
BACKGROUND: Left ventricular (LV) function is dependent on load, intrinsic contractility and relaxation with a variable impact on specific mechanics. Strain (ε) imaging allows the assessment of cardiac function; however, the direct relationship between volume and strain is currently unknown. The aim of this study was to establish the impact of preload reduction through head-up tilt (HUT) testing on simultaneous left ventricular (LV) longitudinal and transverse function and their respective contribution to volume change...
March 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29338775/comparison-of-speckle-tracking-echocardiography-with-invasive-hemodynamics-for-the-detection-of-characteristic-cardiac-dysfunction-in-type-1-and-type-2-diabetic-rat-models
#3
Csaba Mátyás, Attila Kovács, Balázs Tamás Németh, Attila Oláh, Szilveszter Braun, Márton Tokodi, Bálint András Barta, Kálmán Benke, Mihály Ruppert, Bálint Károly Lakatos, Béla Merkely, Tamás Radovits
BACKGROUND: Measurement of systolic and diastolic function in animal models is challenging by conventional non-invasive methods. Therefore, we aimed at comparing speckle-tracking echocardiography (STE)-derived parameters to the indices of left ventricular (LV) pressure-volume (PV) analysis to detect cardiac dysfunction in rat models of type-1 (T1DM) and type-2 (T2DM) diabetes mellitus. METHODS: Rat models of T1DM (induced by 60 mg/kg streptozotocin, n = 8) and T2DM (32-week-old Zucker Diabetic Fatty rats, n = 7) and corresponding control animals (n = 5 and n = 8, respectively) were compared...
January 16, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29332410/myocardial-strain-stress-changes-identified-by-echocardiography-may-reveal-early-sepsis-induced-myocardial-dysfunction
#4
Xiaoting Wang, Longxiang Su, Rongli Yang, Hongmin Zhang, Dawei Liu
Objective To perform early assessment of sepsis-induced myocardial dysfunction (SIMD) using strain/stress echocardiography. Methods A canine model of SIMD was established using intravenous injection of lipopolysaccharide (LPS, 2 mg/kg). Thirteen dogs were included, comprising an LPS-treated SIMD group ( n = 7) and saline control group ( n = 6). SIMD was assessed at various time-points using cardiac measurements including haemodynamics and echocardiography. Results Systolic and radial ventricular wall stress and circular ventricular wall stress (WSsc) were significantly lower in the sepsis group versus the control group at all time-points...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29325795/insertional-mutagenesis-confounds-the-mechanism-of-the-morbid-phenotype-of-a-plnr9c-transgenic-mouse-line
#5
Alexander Kraev
BACKGROUND: A mouse line with heterozygous transgenic expression of phospholamban carrying a substitution of cysteine for arginine 9 (TgPLNR9C) under the control of α-myosin heavy chain (αMHC) promoter features dilated cardiomyopathy, heart failure and premature death. METHODS AND RESULTS: Determination of transgene chromosomal localization by conventional methods shows that in this line the transgenic array of 13 PLNR9C expression cassettes, arranged in a head-to-tail tandem orientation, has integrated into the bi-directional promoter of the αMHC (Myh6) gene and the gene for the regulatory non-coding RNA Myheart (Mhrt), both of which are known to be involved in cardiac development and pathology...
January 8, 2018: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29324576/intermittent-cooling-during-judo-training-in-a-warm-humid-environment-reduces-autonomic-and-hormonal-impact
#6
Eduardo Carballeira, José Morales, David H Fukuda, María L Granada, Vicente Carratalá-Deval, Alfonso López Díaz de Durana, Jeffrey R Stout
The purpose of this study was to identify the effects of superficial cooling on physiological responses while training in a warm, humid environment during an international judo training camp. Sixteen judokas (8 women and 8 men) participated in the experiment. Four high-level women and four men were randomly assigned to wear a cooling vest (vest group, VG) during the recovery periods within a training session (i.e. 8 bouts of 5 min fighting with 5 min rest) and up to 10 min after the session, while the remaining athletes in the control group (CG) trained without the use of any cooling aids...
January 5, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29321822/pursuing-meaningful-end-points-for-stem-cell-therapy-assessment-in-ischemic-cardiac-disease
#7
REVIEW
Maria Dorobantu, Nicoleta-Monica Popa-Fotea, Mihaela Popa, Iulia Rusu, Miruna Mihaela Micheu
Despite optimal interventional and medical therapy, ischemic heart disease is still an important cause of morbidity and mortality worldwide. Although not included in standard of care rehabilitation, stem cell therapy (SCT) could be a solution for prompting cardiac regeneration. Multiple studies have been published from the beginning of SCT until now, but overall no unanimous conclusion could be drawn in part due to the lack of appropriate end-points. In order to appreciate the impact of SCT, multiple markers from different categories should be considered: Structural, biological, functional, physiological, but also major adverse cardiac events or quality of life...
December 26, 2017: World Journal of Stem Cells
https://www.readbyqxmd.com/read/29317621/integrated-omics-dissection-of-proteome-dynamics-during-cardiac-remodeling
#8
Edward Lau, Quan Cao, Maggie P Y Lam, Jie Wang, Dominic C M Ng, Brian J Bleakley, Jessica M Lee, David A Liem, Ding Wang, Henning Hermjakob, Peipei Ping
Transcript abundance and protein abundance show modest correlation in many biological models, but how this impacts disease signature discovery in omics experiments is rarely explored. Here we report an integrated omics approach, incorporating measurements of transcript abundance, protein abundance, and protein turnover to map the landscape of proteome remodeling in a mouse model of pathological cardiac hypertrophy. Analyzing the hypertrophy signatures that are reproducibly discovered from each omics data type across six genetic strains of mice, we find that the integration of transcript abundance, protein abundance, and protein turnover data leads to 75% gain in discovered disease gene candidates...
January 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29317451/duration-of-diabetes-and-prediabetes-during-adulthood-and-subclinical-atherosclerosis-and-cardiac-dysfunction-in-middle-age-the-cardia-study
#9
Jared P Reis, Norrina B Allen, Michael P Bancks, J Jeffrey Carr, Cora E Lewis, Joao A Lima, Jamal S Rana, Samuel S Gidding, Pamela J Schreiner
OBJECTIVE: To determine whether the duration of diabetes and duration of prediabetes estimated during a 25-year period in early adulthood are each independently associated with coronary artery calcified plaque (CAC) and abnormalities in left ventricular structure and function later in life. RESEARCH DESIGN AND METHODS: Participants were 3,628 white and black adults aged 18-30 years without diabetes or prediabetes at baseline (1985-1986) in the Coronary Artery Risk Development in Young Adults (CARDIA) Study...
January 9, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29312873/left-ventricular-deformation-abnormalities-in-a-patient-with-calpainopathy-a-case-from-the-three-dimensional-speckle-tracking-echocardiographic-magyar-path-study
#10
Attila Nemes, Lívia Dézsi, Péter Domsik, Anita Kalapos, Tamás Forster, László Vécsei
Calpainopathy or limb-girdle muscular dystrophy type 2A (LGMD2A) is the most common type of autosomal recessive limb-girdle muscular dystrophies. The disease is caused by mutations in the CAPN3 gene encoding calpain, a protein involved in muscle membrane remodeling and repair. This paper gives an overview of the genetic background, clinical course, and diagnosis of the disease, and presents the first case of calpainopathy in which cardiac deformation mechanics was investigated. Three-dimensional speckle-tracking echocardiography (3DSTE) demonstrated reduced left ventricular (LV) strains and increased LV apical rotation and twist, suggestive of asymptomatic subclinical LV dysfunction...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29306590/new-definition-criteria-of-myocardial-dysfunction-in-patients-with-liver-cirrhosis-a-speckle-tracking-and-tissue-doppler-imaging-study
#11
Roxana Cristina Rimbaş, Sorina Mihăilă Baldea, Ruxandra Drăgoi Galrinho Antunes Guerra, Simona Ionela Visoiu, Mihai Rimbaş, Corina Silvia Pop, Dragoş Vinereanu
There are no clear recommendations regarding cirrhotic cardiomyopathy (CC) evaluation in patients with pre-transplant liver cirrhosis. The roles of new methods, tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) in the diagnosis and prognosis of cirrhotic cardiomyopathy remain controversial. We investigated the utility of TDI/STE parameters in cirrhotic cardiomyopathy diagnosis and also in predicting mortality in patients with liver cirrhosis. Left/right ventricular function was studied using conventional TDI (velocities) and STE (strain/strain rate)...
January 3, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29306544/altered-left-ventricular-geometry-and-torsional-mechanics-in-high-altitude-induced-pulmonary-hypertension-a-three-dimensional-echocardiographic-study
#12
Bart W De Boeck, Aurel Toma, Stephanie Kiencke, Christoph Dehnert, Stefanie Zügel, Christoph Siebenmann, Katja Auinger, Peter T Buser, Marco Maggiorini, Beat A Kaufmann
BACKGROUND: Changes in left ventricular (LV) torsion have been related to LV geometry in patients with concomitant long-standing myocardial disease or pulmonary hypertension (PH). We evaluated the effect of acute high altitude-induced isolated PH on LV geometry, volumes, systolic function, and torsional mechanics. METHODS: Twenty-three volunteers were prospectively studied at low altitude and after the second (D3) and third night (D4) at high altitude (4,559 m)...
January 3, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29306461/assessment-of-left-ventricular-myocardial-deformation-by-cardiac-mri-strain-imaging-reveals-myocardial-dysfunction-in-patients-with-primary-cardiac-tumors
#13
Jing Chen, Zhi-Gang Yang, Hua-Yan Xu, Ke Shi, Ying-Kun Guo
BACKGROUND: To assess left ventricular myocardial deformation in patients with primary cardiac tumors. METHODS: MRI was retrospectively performed in 61 patients, including 31 patients with primary cardiac tumors and 30 matched normal controls. Left ventricular strain and function parameters were then assessed by MRI-tissue tracking. Differences between the tumor group and controls, left and right heart tumor groups, left ventricular wall tumor and non-left ventricular wall tumor groups, and tumors with and without LV enlargement groups were assessed...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29305891/efficacy-of-essential-oil-of-syzygium-aromaticum-alone-and-in-combination-with-benznidazole-on-murine-oral-infection-with-trypanosoma-cruzi-iv
#14
Gerson Zanusso Junior, Miyoko Massago, Danielle Kian, Max Jean de Ornelas Toledo
Chagas disease (CD), caused by Trypanosoma cruzi, remains a serious public health problem. One of the causes of the high morbidity and mortality in patients is the lack of an effective drug therapy. Thus, the aim of this study was to evaluate the efficacy of the essential oil of Syzygium aromaticum alone and in combination with benznidazole (BZ) in mice orally inoculated with strain of T. cruzi IV obtained from oral CD outbreak occurred in Western Brazilian Amazonia. All the animals inoculated with metacyclic trypomastigote forms (AM14 strain, BZ resistant), derived from the insect Rhodnius robustus, became infected and there was no difference in the mortality rate between the experimental groups...
January 3, 2018: Experimental Parasitology
https://www.readbyqxmd.com/read/29301529/increased-myocardial-extracellular-volume-assessed-by-cardiovascular-magnetic-resonance-t1-mapping-and-its-determinants-in-type-2-diabetes-mellitus-patients-with-normal-myocardial-systolic-strain
#15
Yukun Cao, Wenjuan Zeng, Yue Cui, Xiangchuang Kong, Miao Wang, Jie Yu, Shan Zhang, Jing Song, Xu Yan, Andreas Greiser, Heshui Shi
BACKGROUND: Cardiac magnetic resonance (CMR) T1 mapping and tissue-tracking strain analysis are useful quantitative techniques that can characterize myocardial tissue and mechanical alterations, respectively, in patients with early diabetic cardiomyopathy. The purpose of this study was to assess the left ventricular myocardial T1 value, extracellular volume fraction (ECV), and systolic strain in asymptomatic patients with type 2 diabetes mellitus (T2DM) and their underlying relationships with clinical parameters...
January 4, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29298772/the-impact-of-preload-reduction-with-head-up-tilt-testing-on-longitudinal-and-transverse-left-ventricular-mechanics
#16
Caroline Schneider, Lynsey Forsythe, John Somauroo, Keith George, David Oxborough
BACKGROUND: Left ventricular (LV) function is dependent on load, intrinsic contractility and relaxation with a variable impact on specific mechanics. Strain (ε) imaging allows the assessment of cardiac function however the direct relationship between volume and strain is currently unknown. The aim of this study was to establish the impact of preload reduction through head-up tilt (HUT) testing on simultaneous left ventricular (LV) longitudinal and transverse function and their respective contribution to volume change...
January 3, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29298692/an-in-vivo-comparison-of-stimulated-echo-and-motion-compensated-spin-echo-sequences-for-3%C3%A2-t-diffusion-tensor-cardiovascular-magnetic-resonance-at-multiple-cardiac-phases
#17
Andrew D Scott, Sonia Nielles-Vallespin, Pedro F Ferreira, Zohya Khalique, Peter D Gatehouse, Philip Kilner, Dudley J Pennell, David N Firmin
BACKGROUND: Stimulated-echo (STEAM) and, more recently, motion-compensated spin-echo (M2-SE) techniques have been used for in-vivo diffusion tensor cardiovascular magnetic resonance (DT-CMR) assessment of cardiac microstructure. The two techniques differ in the length scales of diffusion interrogated, their signal-to-noise ratio efficiency and sensitivity to both motion and strain. Previous comparisons of the techniques have used high performance gradients at 1.5 T in a single cardiac phase...
January 3, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29288409/gene-expression-analysis-to-identify-mechanisms-underlying-heart-failure-susceptibility-in-mice-and-humans
#18
Christoph Koentges, Mark E Pepin, Carolyn Müsse, Katharina Pfeil, Sonia V Viteri Alvarez, Natalie Hoppe, Michael M Hoffmann, Katja E Odening, Samuel Sossalla, Andreas Zirlik, Lutz Hein, Christoph Bode, Adam R Wende, Heiko Bugger
Genetic factors are known to modulate cardiac susceptibility to ventricular hypertrophy and failure. To determine how strain influences the transcriptional response to pressure overload-induced heart failure (HF) and which of these changes accurately reflect the human disease, we analyzed the myocardial transcriptional profile of mouse strains with high (C57BL/6J) and low (129S1/SvImJ) susceptibility for HF development, which we compared to that of human failing hearts. Following transverse aortic constriction (TAC), C57BL/6J mice developed overt HF while 129S1/SvImJ did not...
December 29, 2017: Basic Research in Cardiology
https://www.readbyqxmd.com/read/29288355/ucs-protein-function-is-partially-restored-in-the-saccharomyces-cerevisiae-she4-mutant-with-expression-of-the-human-unc45-gc-but-not-unc45-sm
#19
Susana Gómez Escalante, Joseph A Brightmore, Peter W Piper, Stefan H Millson
A dedicated UNC45, Cro1, She4 (UCS) domain-containing protein assists in the Hsp90-mediated folding of the myosin head. Only weak sequence conservation exists between the single UCS protein of simple eukaryotes (She4 in budding yeast) and the two UCS proteins of higher organisms (the general cell and striated muscle UNC45s; UNC45-GC and UNC45-SM, respectively). In vertebrates, UNC45-GC facilitates cytoskeletal functions, whereas the 55% identical UNC45-SM assists assembly of the contractile apparatus of cardiac and skeletal muscles...
December 29, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29286554/effect-of-intravenous-administration-of-cobalt-chloride-to-horses-on-clinical-and-hemodynamic-variables
#20
T A Burns, K A Dembek, A Kamr, S B Dooley, L K Dunbar, T K Aarnes, L S Bednarski, C O'Brien, J Lakritz, B Byrum, A Wade, R Farmer, S Tan, R E Toribio
BACKGROUND: Cobalt chloride (CoCl2 ) is administered to racehorses to enhance performance. The purpose of this study was to evaluate the clinical, cardiovascular, and endocrine effects of parenterally administered CoCl2 . OBJECTIVES: To describe the effects of weekly intravenous doses of CoCl2 on Standardbred horses. ANIMALS: Five, healthy Standardbred mares. METHODS: Prospective, randomized, experimental dose-escalation pilot...
December 29, 2017: Journal of Veterinary Internal Medicine
keyword
keyword
21773
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"