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https://www.readbyqxmd.com/read/29226282/feasibility-of-conducting-a-6-month-long-home-based-exercise-program-with-protein-supplementation-in-elderly-community-dwelling-individuals-with-heart-failure
#1
Masil George, Gohar Azhar, Amanda Pangle, Eric Peeler, Amanda Dawson, Robert Coker, Kellie S Coleman, Amy Schrader, Jeanne Wei
Objective: Cardiac cachexia is a condition associated with heart failure, particularly in the elderly, and is characterized by loss of muscle mass with or without the loss of fat mass. Approximately 15% of elderly heart failure patients will eventually develop cardiac cachexia; such a diagnosis is closely associated with high morbidity and increased mortality. While the mechanism(s) involved in the progression of cardiac cachexia is incompletely established, certain factors appear to be contributory...
2017: Journal of Physiotherapy & Physical Rehabilitation
https://www.readbyqxmd.com/read/29110079/old-and-emerging-concepts-on-adrenal-chromaffin-cell-stimulus-secretion-coupling
#2
EDITORIAL
Ricardo Borges, Luis Gandía, Emilio Carbone
The chromaffin cells (CCs) of the adrenal medulla play a key role in the control of circulating catecholamines to adapt our body function to stressful conditions. A huge research effort over the last 35 years has converted these cells into the Escherichia coli of neurobiology. CCs have been the testing bench for the development of patch-clamp and amperometric recording techniques and helped clarify most of the known molecular mechanisms that regulate cell excitability, Ca(2+) signals associated with secretion, and the molecular apparatus that regulates vesicle fusion...
November 6, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/29104251/influence-of-glycine-and-arginine-on-cylindrospermopsin-production-and-aoa-gene-expression-in-aphanizomenon-ovalisporum
#3
Ángel Barón-Sola, Francisca Fernández Del Campo, Soledad Sanz-Alférez
Arginine (Arg) and glycine (Gly) seem to be the only substrates accepted by the amidinotransferase that catalyze the first step of the synthesis pathway of the cyanotoxin cylindrospermopsin (CYN), leading to guanidinoacetate (GAA). Here, the effect of these amino acids on the production of CYN in cultures of the cylindrospermopsin-producing strain, Aphanizomenon ovalisporum UAM-MAO, has been studied. Arg clearly increased CYN content, the increment appearing triphasic along the culture. On the contrary, Gly caused a decrease of CYN, observable from the first day on...
November 1, 2017: Toxins
https://www.readbyqxmd.com/read/29077700/electroencephalographic-indicators-in-default-mode-habituation-and-visual-motor-association-in-female-college-students
#4
Héctor Brust-Carmona, Yessica Martínez-Serrato, Ana Sánchez-Quezada, Blanca Flores-Avalos, Javier Alducin-Castillo, Oscar Yáñez-Suarez
BACKGROUND: Oscillations, action, and postsynaptic potentials in glial-neuronal ensembles integrate the spectral power (SP) of electroencephalographic (EEG). Our objective is to propose SP indicators of healthy brains (control groups) based on the default mode and their modifications by habituation and visual-motor association (VM-asso), to support diagnostic and rehabilitation processes. However, important differences seem to exist between men and women. Therefore, we aim to analyze EEG characteristics in a female sample...
September 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29056625/the-development-of-a-community-engagement-workshop-a-community-led-approach-for-building-researcher-capacity
#5
Jake Coffey, Anna Huff-Davis, Christie Lindsey, Onie Norman, Henryetter Curtis, Calvin Criner, M Kathryn Stewart
BACKGROUND: Although community-engaged research (CEnR) is increasingly promoted in the literature, academic programs often fail to prepare researchers for the critical, ethical, and power issues involved in CEnR. This article documents a community-created and led workshop for CEnR researchers. OBJECTIVES: The workshop's main objective is to increase researchers' knowledge and felt experience of the "dos and don'ts" of CEnR in three research domains: entering the community, accommodating the realities and constraints of community-based organizations, and dissemination...
2017: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29056624/community-health-warriors-marshallese-community-health-workers-perceptions-and-experiences-with-cbpr-and-community-engagement
#6
Rachel S Purvis, Williamina Ioanna Bing, Christopher J Jacob, Sharlynn Lang, Sammie Mamis, Mandy Ritok, Jellesen Rubon-Chutaro, Pearl Anna McElfish
Our manuscript highlights the viewpoints and reflections of the native Marshallese community health workers (CHWs) engaged in research with the local Marshallese community in Northwest Arkansas. In particular, this paper documents the vital role Marshallese CHWs play in the success of programs and research efforts. The negative health effects of nuclear testing in the Marshall Islands has been passed down through many generations, along with unfavorable attitudes toward the U.S. government and researchers. However, the community-based participatory research (CBPR) approach used by the University of Arkansas for Medical Sciences (UAMS) has allowed the native Marshallese CHWs to become advocates for the Marshallese community...
2017: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29052022/udp-arabinopyranose-mutase-gene-expressions-are-required-for-the-biosynthesis-of-the-arabinose-side-chain-of-both-pectin-and-arabinoxyloglucan-and-normal-leaf-expansion-in-nicotiana-tabacum
#7
Hideyuki Honta, Takuya Inamura, Teruko Konishi, Shinobu Satoh, Hiroaki Iwai
Plant cell walls are composed of polysaccharides such as cellulose, hemicelluloses, and pectins, whose location and function differ depending on plant type. Arabinose is a constituent of many different cell wall components, including pectic rhamnogalacturonan I (RG-I) and II (RG-II), glucuronoarabinoxylans (GAX), and arabinoxyloglucan (AXG). Arabinose is found predominantly in the furanose rather than in the thermodynamically more stable pyranose form. The UDP-arabinopyranose mutases (UAMs) have been demonstrated to convert UDP-arabinopyranose (UDP-Arap) to UDP-arabinofuranose (UDP-Araf) in rice (Oryza sativa L...
October 19, 2017: Journal of Plant Research
https://www.readbyqxmd.com/read/29048486/cancer-progression-models-and-fitness-landscapes-a-many-to-many-relationship
#8
Ramon Diaz-Uriarte
Motivation: The identification of constraints, due to gene interactions, in the order of accumulation of mutations during cancer progression can allow us to single out therapeutic targets. Cancer progression models (CPMs) use genotype frequency data from cross-sectional samples to identify these constraints, and return Directed Acyclic Graphs (DAGs) of restrictions where arrows indicate dependencies or constraints. On the other hand, fitness landscapes, which map genotypes to fitness, contain all possible paths of tumor progression...
October 18, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28946440/in-situ-development-of-highly-photocatalytic-multifunctional-nanocomposites-by-ultrasonic-acoustic-method
#9
Muhammad Tayyab Noman, Jakub Wiener, Jana Saskova, Muhammad Azeem Ashraf, Martina Vikova, Hafsa Jamshaid, Pavel Kejzlar
Cotton-titania nanocomposites with multifunctional properties were synthesized through ultrasonic acoustic method (UAM). Ultrasonic irradiations were used as a potential tool to develop cotton-titania (CT) nanocomposites at low temperature in the presence of titanium tetrachloride and isopropanol. The synthesized samples were characterized by XRD, SEM, EDX and ICP-OES methods. Functional properties i.e. Ultraviolet protection factor (UPF), self-cleaning, washing durability, antimicrobial and tensile strength of the CT nanocomposites were evaluated by different methods...
January 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28872535/the-opportunity-awaits-to-lead-orthopaedic-telehealth-innovation-aoa-critical-issues
#10
Montri D Wongworawat, Gary Capistrant, John M Stephenson
Telehealth is a way to provide health-care services to a patient from a provider who is at another location. The most common methods include a live interactive visit with the patient, interpretation of imaging, and monitoring of patient progress. Principally, telehealth is a way of providing a service rather than a type of service. It is about patient care, not data care.Examples of orthopaedic applications include conducting patient examinations, interpreting imaging studies, and providing postoperative care...
September 6, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28842287/determining-potential-of-pmma-as-a-depot-for-rifampin-to-treat-recalcitrant-orthopaedic-infections
#11
Stefanie M Shiels, David J Tennent, Kevin S Akers, Joseph C Wenke
BACKGROUND: Open fractures are often complicated by infection. In cases of severe soft tissue and vascular injury, systemic antibiotics may be ineffective due to their inability to reach and provide direct antimicrobial activity to the zone of injury. High antibiotic concentrations within the wound can be achieved with reduced systemic toxicity by using local antibiotic delivery. As bacteria associated with musculoskeletal injuries frequently form biofilms, antibiotic selection is important...
October 2017: Injury
https://www.readbyqxmd.com/read/28818899/draft-genome-sequence-of-sphingobacterium-sp-cz-uam-isolated-from-a-methanotrophic-consortium
#12
José Luis Steffani-Vallejo, Cristal Zuñiga, Pablo Cruz-Morales, Luis Lozano, Marcia Morales, Cuauhtemoc Licona-Cassani, Sergio Revah, José Utrilla
Sphingobacterium sp. CZ-UAM was isolated from a methanotrophic consortium in mineral medium using methane as the only carbon source. A draft genome of 5.84 Mb with a 40.77% G+C content is reported here. This genome sequence will allow the investigation of potential methanotrophy in this isolated strain.
August 17, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28789800/rapid-ultrasonic-and-microwave-assisted-micellar-extraction-of-zingiberone-shogaol-and-gingerols-from-gingers-using-biosurfactants
#13
Li-Qing Peng, Jun Cao, Li-Jing Du, Qi-Dong Zhang, Jing-Jing Xu, Yu-Bo Chen, Yu-Ting Shi, Rong-Rong Li
Two kinds of extraction methods ultrasonic-assisted micellar extraction (UAME) and microwave-assisted micellar extraction (MAME) coupled with ultra-high performance liquid chromatography with ultraviolet detector (UHPLC-UV) were developed and evaluated for extraction and determination of zingerone, 6-gingerol, 8-gingerol, 6-shogaol and 10-gingerol in Rhizoma Zingiberis and Rhizoma Zingiberis Preparata. A biosurfactant, hyodeoxycholic acid sodium salt, was used in micellar extraction. Several experimental parameters were studied separately by a univariate method...
September 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28655399/sonochemical-synthesis-of-highly-crystalline-photocatalyst-for-industrial-applications
#14
Muhammad Tayyab Noman, Jiri Militky, Jakub Wiener, Jana Saskova, Muhammad Azeem Ashraf, Hafsa Jamshaid, Musaddaq Azeem
Highly photo active pure anatase form of TiO2 nanoparticles with average particle size 4nm have been successfully synthesized by ultrasonic acoustic method (UAM). The effects of process variables i.e. precursors concentration and sonication time were investigated based on central composite design and response surface methodology. The characteristics of the resulting nanoparticles (RNP) were analyzed by scanning electron microscopy, dynamic light scattering, transmission electron microscopy, X-ray diffractometry and Raman spectroscopy...
June 20, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28448019/a-tandem-liquid-chromatography-mass-spectrometry-based-approach-for-metabolite-analysis-of-staphylococcus-aureus
#15
David J Samuels, Zhe Wang, Kyu Y Rhee, Shaun R Brinsmade
In an effort to thwart bacterial pathogens, hosts often limit the availability of nutrients at the site of infection. This limitation can alter the abundances of key metabolites to which regulatory factors respond, adjusting cellular metabolism. In recent years, a number of proteins and RNA have emerged as important regulators of virulence gene expression. For example, the CodY protein responds to levels of branched-chain amino acids and GTP and is widely conserved in low G+C Gram-positive bacteria. As a global regulator in Staphylococcus aureus, CodY controls the expression of dozens of virulence and metabolic genes...
March 28, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28368284/x-ray-diffraction-analysis-and-in-vitro-characterization-of-the-uam2-protein-from-oryza-sativa
#16
Ditte Hededam Welner, Alex Yi Lin Tsai, Andy M DeGiovanni, Henrik Vibe Scheller, Paul D Adams
The role of seemingly non-enzymatic proteins in complexes interconverting UDP-arabinopyranose and UDP-arabinofuranose (UDP-arabinosemutases; UAMs) in the plant cytosol remains unknown. To shed light on their function, crystallographic and functional studies of the seemingly non-enzymatic UAM2 protein from Oryza sativa (OsUAM2) were undertaken. Here, X-ray diffraction data are reported, as well as analysis of the oligomeric state in the crystal and in solution. OsUAM2 crystallizes readily but forms highly radiation-sensitive crystals with limited diffraction power, requiring careful low-dose vector data acquisition...
April 1, 2017: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/28269237/defining-new-aims-for-bme-programs-in-latin-america-the-case-of-uam-iztapalapa
#17
J Azpiroz-Leehan, L F Martinez, M E G Urbina, M M Cadena, E Sacristan
The need for upkeep and management of medical technology has fostered the creation of a large number of under graduate programs in the field of biomedical Engineering. In Latin America alone, there are over 85 programs dedicated to this. This contrasts with programs in other regions where most of the undergraduates continue on to pursue graduate degrees or work as research and development engineers in the biomedical industry. In this work we analyze the situation regarding curricular design in the 48 BME programs in Mexico and compare this to suggestions and classifications of programs according to needs and possibilities...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227471/defining-new-aims-for-bme-programs-in-latin-america-the-case-of-uam-iztapalapa
#18
J Azpiroz-Leehan, L F Martinez, M E G Urbina, M M Cadena, E Sacristan, J Azpiroz-Leehan, L F Martinez, M E G Urbina, M M Cadena, E Sacristan, M M Cadena, M E G Urbina, E Sacristan, J Azpiroz-Leehan, L F Martinez
The need for upkeep and management of medical technology has fostered the creation of a large number of under graduate programs in the field of biomedical Engineering. In Latin America alone, there are over 85 programs dedicated to this. This contrasts with programs in other regions where most of the undergraduates continue on to pursue graduate degrees or work as research and development engineers in the biomedical industry. In this work we analyze the situation regarding curricular design in the 48 BME programs in Mexico and compare this to suggestions and classifications of programs according to needs and possibilities...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28192204/analysis-of-plant-udp-arabinopyranose-mutase-uam-role-of-divalent-metals-and-structure-prediction
#19
Jijin R A Kuttiyatveetil, David A R Sanders
UDP-arabinopyranose mutase (UAM) is a plant enzyme which interconverts UDP-arabinopyranose (UDP-Arap; a six-membered sugar) to UDP-arabinofuranose (UDP-Araf; a five-membered sugar). Plant mutases belong to a small gene family called Reversibly Glycosylated Proteins (RGPs). So far, UAM has been identified in Oryza sativa (Rice), Arabidopsis thaliana and Hordeum vulgare (Barley). The enzyme requires divalent metal ions for catalytic activity. Here, the divalent metal ion dependency of UAMs from O. sativa (rice) and A...
May 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28106469/building-a-dna-barcode-library-of-alaska-s-non-marine-arthropods
#20
Derek S Sikes, Matthew Bowser, John M Morton, Casey Bickford, Sarah Meierotto, Kyndall Hildebrandt
Climate change may result in ecological futures with novel species assemblages, trophic mismatch, and mass extinction. Alaska has a limited taxonomic workforce to address these changes. We are building a DNA barcode library to facilitate a metabarcoding approach to monitoring non-marine arthropods. Working with the Canadian Centre for DNA Barcoding, we obtained DNA barcodes from recently collected and authoritatively identified specimens in the University of Alaska Museum (UAM) Insect Collection and the Kenai National Wildlife Refuge collection...
March 2017: Genome Génome / Conseil National de Recherches Canada
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