keyword
https://read.qxmd.com/read/38633829/the-impact-of-pre-biopsy-mri-and-additional-testing-on-prostate-cancer-screening-outcomes-a-rapid-review
#1
REVIEW
Abel Tesfai, Natalia Norori, Thomas A Harding, Yui Hang Wong, Matthew David Hobbs
OBJECTIVE: This work aims to examine the latest evidence on the impact of pre-biopsy MRI, in addition to prostate-specific antigen (PSA) testing, on health outcomes and quality of life. METHODS: We conducted a literature search including PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) databases, with a limited scan of (i) guidelines and (ii) references from trial reports, from January 2005 to 25th January 2023. Two independent reviewers selected randomised controlled trials (RCT) and cohort studies which met our inclusion criteria...
April 2024: BJUI compass
https://read.qxmd.com/read/38631790/initial-triage-and-management-of-patients-with-acute-aortic-syndromes
#2
REVIEW
Willard N Applefeld, Jacob C Jentzer
The acute aortic syndromes (AAS) are life-threatening vascular compromises within the aortic wall. These include aortic dissection (AD), intramural hematoma (IMH), penetrating aortic ulcer (PAU), and blunt traumatic thoracic aortic injury (BTTAI). While patients classically present with chest pain, the presentation may be highly variable. Timely diagnosis is critical to initiate definitive treatment and maximize chances of survival. In high-risk patients, treatment should begin immediately, even while diagnostic evaluation proceeds...
May 2024: Cardiology Clinics
https://read.qxmd.com/read/38629335/protective-and-risk-factors-of-workplace-violence-against-nurses-a-cross-sectional-study
#3
JOURNAL ARTICLE
Annamaria Bagnasco, Gianluca Catania, Nicola Pagnucci, Rosaria Alvaro, Giancarlo Cicolini, Alberto Dal Molin, Loreto Lancia, Maura Lusignani, Daniela Mecugni, Paolo Carlo Motta, Roger Watson, Mark Hayter, Fiona Timmins, Giuseppe Aleo, Francesca Napolitano, Alessio Signori, Milko Zanini, Loredana Sasso, Beatrice Mazzoleni
AIMS: To describe how workplace violence (WPV) is experienced by nurses in hospitals and community services and identify protective and risk factors. METHODS: An online cross-sectional national study was conducted from January to April 2021 in Italy. Hospitals and community services were involved in the study. The survey combined the adapted and validated Italian version of the Violence in Emergency Nursing and Triage (VENT) questionnaire, which explores the episodes of WPV experienced during the previous 12 months, the Practice Environment Scale of the Nursing Work Index (PES-NWI) and some additional questions about staffing levels extracted from a previous RN4CAST study...
April 17, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38628286/determination-categorization-and-hierarchy-of-content-for-a-pediatric-emergency-medicine-curriculum-designed-for-emergency-medicine-residents
#4
JOURNAL ARTICLE
Sarah C Cavallaro, Sara Schutzman, Joyce Li, Martin Pusic
BACKGROUND: Currently, the Accreditation Council of Graduate Medical Education requires time-based pediatric experiences for emergency medicine (EM) residents in both pediatric emergency medicine (PEM) and critical care settings. The American Board of Emergency Medicine has published the Model of the Clinical Practice of Emergency Medicine, which is a list of content an EM resident should learn. However, this list is large and without prioritization and therefore can be difficult to incorporate into time-limited curricula...
April 2024: AEM Education and Training
https://read.qxmd.com/read/38628253/examining-the-need-for-a-high-level-of-therapeutic-security-at-a-regional-forensic-mental-health-service-in-aotearoa-new-zealand
#5
JOURNAL ARTICLE
Michael Jewell, Krishna Pillai, James Cavney, Nick Garrett, Brian McKenna
The ceiling of therapeutic security in Aotearoa New Zealand is medium security. The aim of this study is to identify and characterise a putative cohort of high-secure patients at a medium-secure regional forensic mental health service. A retrospective review of all admissions to a specific service was conducted over 3.75 years. The Dangerousness Understanding, Recovery and Urgency Manual, Triage Security Scale (DUNDRUM-1) was used to identify patients with high-secure care needs. A multiple logistic regression analysis was used to identify the local needs of this cohort...
2024: Psychiatry, Psychology, and Law: An Interdisciplinary Journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law
https://read.qxmd.com/read/38627583/influencing-factors-on-the-time-to-ct-in-suspected-pulmonary-embolism-an-explorative-investigation
#6
JOURNAL ARTICLE
Daniel Koehler, Ann-Kathrin Ozga, Isabel Molwitz, Farzad Shenas, Sarah Keller, Gerhard Adam, Jin Yamamura
Pulmonary embolism is a potentially fatal condition with increased mortality if anticoagulation is delayed. This study aimed to find influencing factors on the duration from requesting a computed tomography (CT) pulmonary angiography (CTPA) to performing a CTPA in suspected acute pulmonary embolism. In 1849 cases, automatically generated time data were extracted from the radiological information system. The impact of the distance to the scanner, case-related features (sector of patient care, triage), and workload (demand for CTs, performed CTs, available staff, hospital occupancy) were investigated retrospectively using multiple regression...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627545/enhancing-ophthalmic-triage-identification-of-new-clinical-features-to-support-healthcare-professionals-in-triage
#7
JOURNAL ARTICLE
Anish Jindal, Camilo Brandao-de-Resende, Yan Ning Neo, Mariane Melo, Alexander C Day
OBJECTIVE: To investigate which features from a patient's history are either high or low risk that could support healthcare professionals in ophthalmic emergency triage. METHODS: Prospective, 12,584 visits from 11,733 adult patients attending an Accident and Emergency department at a single tertiary centre were analysed. Data were collected by ophthalmic nurses working in triage, using an online form from August 2021 to April 2022. Multivariate analysis (MVA) was conducted to identify which features from the patients' history would be associated with emergency care...
April 16, 2024: Eye
https://read.qxmd.com/read/38627288/association-of-clinical-outcome-and-imaging-endpoints-in-extensive-ischemic-stroke-comparing-measures-of-cerebral-edema
#8
JOURNAL ARTICLE
Vincent Geest, Paul Steffen, Laurens Winkelmeier, Tobias D Faizy, Christian Heitkamp, Helge Kniep, Lukas Meyer, Kamil Zelenak, Thomalla Götz, Jens Fiehler, Gabriel Broocks
OBJECTIVES: Ischemic edema is associated with worse clinical outcomes, especially in large infarcts. Computed tomography (CT)-based densitometry allows direct quantification of absolute edema volume (EV), which challenges indirect biomarkers like midline shift (MLS). We compared EV and MLS as imaging biomarkers of ischemic edema and predictors of malignant infarction (MI) and very poor clinical outcome (VPCO) in early follow-up CT of patients with large infarcts. MATERIALS AND METHODS: Patients with anterior circulation stroke, large vessel occlusion, and Alberta Stroke Program Early CT Score (ASPECTS) ≤ 5 were included...
April 16, 2024: European Radiology
https://read.qxmd.com/read/38626475/overtriage-of-transfers-to-the-pediatric-trauma-center-the-importance-of-minor-head-injury
#9
JOURNAL ARTICLE
Kristin Haag, Duane Duke, Joseph Piatt
OBJECTIVE: Accurate triage of minor head injuries remains a challenge for mature trauma systems. More than one-third of trauma transfers are overtriaged, and minor head injuries predominate. Overtriage is inefficient, wasteful of resources, and burdensome for families. The authors studied overtriage at the sole level I pediatric trauma center (PTC) in a small state with a view toward improvement of processes. METHODS: Data on transfer patients were extracted from an institutional trauma registry over an 8-year period...
April 19, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38622755/short-waits-happy-patients-and-expert-care-moving-basic-musculoskeletal-care-from-the-emergency-department-to-a-physiotherapist-led-diversion-pathway
#10
JOURNAL ARTICLE
Piers Truter, Pippa Flanagan, Robert Waller, Karen Richards, Marshall Makate, Anthony Johnstone, Luke Bongiascia, Katrina Spilsbury, Vinicius Cavalheri, Ivan Lin
OBJECTIVE: Patients with musculoskeletal conditions (MSKCs) are highly prevalent in ED. This project explores the impact of the pilot phase of a 'diversion pathway', which directed patients with MSKCs from the ED waiting room to an outpatient clinic led by advanced-scope physiotherapists. METHODS: A prospective intervention study comparing care outcomes between patients in the 'diversion pathway' with usual ED care. The characteristics of patients considered eligible and non-eligible are described...
April 15, 2024: Emergency Medicine Australasia: EMA
https://read.qxmd.com/read/38621798/feasibility-of-physiotherapist-led-rheumatology-triage-a-randomized-study
#11
JOURNAL ARTICLE
Janet H Roberts, Cheri Gun, Jennifer E Mackinnon, Susan Parlee, Volodko Bakowsky, Trudy Taylor, Claire E H Barber, John G Hanly
OBJECTIVE: Given global shortages in the rheumatology workforce, the demand for rheumatology assessment often exceeds the capacity to provide timely access to care. Accurate triage of patient referrals is important to ensure appropriate utilization of finite resources. We assessed the feasibility of physiotherapist-led triage utilizing a standardized protocol, in identifying cases of inflammatory arthritis (IA), as compared to usual rheumatologist triage of referrals for joint pain, in a tertiary care rheumatology clinic...
April 15, 2024: Journal of Rheumatology
https://read.qxmd.com/read/38619077/recommendations-for-the-management-of-initial-and-refractory-pediatric-status-dystonicus
#12
REVIEW
Lindsey M Vogt, Kathryn Yang, Gabriel Tse, Vicente Quiroz, Zainab Zaman, Laura Wang, Rasha Srouji, Amy Tam, Elicia Estrella, Shannon Manzi, Alfonso Fasano, Weston T Northam, Scellig Stone, Mahendranath Moharir, Hernan Gonorazky, Brian McAlvin, Monica Kleinman, Kerri L LaRovere, Carolina Gorodetsky, Darius Ebrahimi-Fakhari
Status dystonicus is the most severe form of dystonia with life-threatening complications if not treated promptly. We present consensus recommendations for the initial management of acutely worsening dystonia (including pre-status dystonicus and status dystonicus), as well as refractory status dystonicus in children. This guideline provides a stepwise approach to assessment, triage, interdisciplinary treatment, and monitoring of status dystonicus. The clinical pathways aim to: (1) facilitate timely recognition/triage of worsening dystonia, (2) standardize supportive and dystonia-directed therapies, (3) provide structure for interdisciplinary cooperation, (4) integrate advances in genomics and neuromodulation, (5) enable multicenter quality improvement and research, and (6) improve outcomes...
April 15, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38618693/near-infrared-responsive-gold-nanorods-for-highly-sensitive-colorimetric-and-photothermal-lateral-flow-immuno-detection-of-sars-cov-2
#13
JOURNAL ARTICLE
Xiaohui Liu, Jingwen Li, Kun Wang, Xiang Li, Shenming Wang, Gengchen Guo, Qiaowen Zheng, Maosheng Zhang, Jingbin Zeng
The highly infectious characteristics of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlight the necessity of sensitive and rapid nucleocapsid (N) protein-based antigen testing for early triage and epidemic management. In this study, a colorimetric and photothermal dual-mode lateral flow immunoassay (LFIA) platform for the rapid and sensitive detection of the SARS-CoV-2 N protein was developed based on gold nanorods (GNRs), which possessed tunable local surface plasma resonance (LSPR) absorption peaks from UV-visible to near-infrared (NIR)...
April 15, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38618472/development-of-predictive-models-based-on-biochemical-parameters-to-triage-covid-19-patients-a-study-conducted-in-a-tertiary-care-hospital
#14
JOURNAL ARTICLE
Mainak Sinha, Ayan Banerjee, Sushil Kumar, Mala Mahto, Bandana Kumari, Alok Ranjan, Akash Bansal
Background The COVID-19 disease continues to cause severe mortality and morbidity. Biochemical parameters are being used to predict the severity of the infection. This study aims to predict disease severity and mortality to help reduce mortality through timely intervention in a cost-effective way. Methods A total of 324 COVID-19 cases admitted at our hospital (All India Institute of Medical Sciences, Patna, BR, India) between June 2020 to December 2020 (phase 1: 190 patients) and April 2021 to May 2021 (phase 2: 134 patients) were recruited for this study...
March 2024: Curēus
https://read.qxmd.com/read/38618345/the-value-of-emergency-care-data-set-ecds-presentation-codes-for-predicting-mortality-and-inpatient-admission
#15
JOURNAL ARTICLE
Betsy Teresa, Mohammed Subhi, Adrian Boyle, Wayne Kark
BACKGROUND:  Early identification of patients at higher risk of death and hospital admission is an important problem in Emergency Departments (ED). Most triage scales were developed before current electronic healthcare records were developed. The implementation of a national Emergency Care Data Set (ECDS) allows for the standardised recording of presenting complaints and the use of Electronic Patient Records (EPR) offers the potential for automated triage. The mortality risk and need for hospital admission associated with the different presenting complaints in a standardised national data set has not been previously reported...
March 2024: Curēus
https://read.qxmd.com/read/38617458/innovative-pathways-allow-safe-discharge-of-mild-acute-pancreatitis-from-the-emergency-room
#16
EDITORIAL
Darshan J Kothari, Sunil G Sheth
Acute pancreatitis (AP) is a leading cause of gastrointestinal-related hospitalizations in the United States, resulting in 300000 admissions per year with an estimated cost of over $2.6 billion annually. The severity of AP is determined by the presence of pancreatic complications and end-organ damage. While moderate/severe pancreatitis can be associated with significant morbidity and mortality, the majority of patients have a mild presentation with an uncomplicated course and mortality rate of less than 2%...
March 21, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38616431/value-of-multi-modality-small-fiber-assessments-in-a-genotypically-diverse-cohort-of-transthyretin-related-amyloidosis-in-the-early-stages-of-disease
#17
JOURNAL ARTICLE
Monica Alcantara, Shabber Mannan, James de la Cruz, Vera Bril
INTRODUCTION: Transthyretin-related amyloidosis (ATTRv) is a progressive multisystem disorder, predominantly involving the peripheral nerve system (PNS) and heart. Quantification of small fiber damage may help guide treatment decisions, as amyloid deposits frequently affect those fibers early in disease course. Corneal confocal microscopy (CCM) is a promising method to monitor patients with ATTRv, due to similarities between corneal nerves and PNS, as the cornea is innervated by Aδ and C fibers...
April 13, 2024: Medicina Clínica
https://read.qxmd.com/read/38615096/dynamics-of-dna-damage-induced-nuclear-inclusions-are-regulated-by-sumoylation-of-btn2
#18
JOURNAL ARTICLE
Arun Kumar, Veena Mathew, Peter C Stirling
Spatial compartmentalization is a key facet of protein quality control that serves to store disassembled or non-native proteins until triage to the refolding or degradation machinery can occur in a regulated manner. Yeast cells sequester nuclear proteins at intranuclear quality control bodies (INQ) in response to various stresses, although the regulation of this process remains poorly understood. Here we reveal the SUMO modification of the small heat shock protein Btn2 under DNA damage and place Btn2 SUMOylation in a pathway promoting protein clearance from INQ structures...
April 13, 2024: Nature Communications
https://read.qxmd.com/read/38613475/clinical-implications-of-over-and-under-triage-using-need-for-trauma-intervention-and-cribari-indices
#19
JOURNAL ARTICLE
Emily K Lenart, Saskya E Byerly, Megan G Gross, Yasmin M Ali, Cory R Evans, Thomas S Easterday, Isaac W Howley, Andy J Kerwin, Peter E Fischer, Dina M Filiberto
BACKGROUND: Need for Trauma Intervention (NFTI) score was proposed to help identify injured trauma patients while minimizing under (UT) and over triage (OT). Using a national database, we aimed to describe UT and OT of NFTI vs standard Cribari method (CM) and hypothesized triage sensitivity remains poor. METHODS: The 2021 Trauma Quality Improvement Program (TQIP) database was queried. Demographics, mechanism, verification level, interfacility transfer (IF), and level of activation were collected...
April 13, 2024: American Surgeon
https://read.qxmd.com/read/38612984/potential-drug-nutrient-interactions-of-45-vitamins-minerals-trace-elements-and-associated-dietary-compounds-with-acetylsalicylic-acid-and-warfarin-a-review-of-the-literature
#20
REVIEW
David Renaud, Alexander Höller, Miriam Michel
In cardiology, acetylsalicylic acid (ASA) and warfarin are among the most commonly used prophylactic therapies against thromboembolic events. Drug-drug interactions are generally well-known. Less known are the drug-nutrient interactions (DNIs), impeding drug absorption and altering micronutritional status. ASA and warfarin might influence the micronutritional status of patients through different mechanisms such as binding or modification of binding properties of ligands, absorption, transport, cellular use or concentration, or excretion...
March 26, 2024: Nutrients
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