keyword
https://read.qxmd.com/read/38536202/venous-disorders-as-an-occupational-disease-a-systematic-review-on-epidemiology-pathophysiology-and-modification-strategies
#1
REVIEW
Tobias Hirsch, Uwe Wahl, Eberhard Rabe
<b/> Background: Forced postures are common in the workplace. Work in the primary economic sector is characterised by a high degree of physical activity and movement; however, activities in the secondary and tertiary sectors commonly require workers to stand or sit. An expansion of the tertiary sector in recent decades has meant that people in industrialised and emerging economies primarily sit or stand at work. The aim of the systematic review was to identify occupational factors relating to the presence of chronic venous disease (CVD), to place these in the context of developments in the workplace, and to determine whether measures are in place to prevent CVD...
March 27, 2024: VASA. Zeitschrift Für Gefässkrankheiten
https://read.qxmd.com/read/38533942/statin-twitter-human-and-automated-bot-contributions-2010-to-2022
#2
JOURNAL ARTICLE
Samuel D Slavin, Adam N Berman, Andrew L Beam, Ann Marie Navar, Murray A Mittleman
BACKGROUND: Many individuals eligible for statin therapy decline treatment, often due to fear of adverse effects. Misinformation about statins is common and drives statin reluctance, but its prevalence on social media platforms, such as Twitter (now X) remains unclear. Social media bots are known to proliferate medical misinformation, but their involvement in statin-related discourse is unknown. This study examined temporal trends in volume, author type (bot or human), and sentiment of statin-related Twitter posts (tweets)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533161/effectiveness-of-recent-physiotherapy-techniques-along-with-conventional-physiotherapy-techniques-in-a-patient-with-knee-osteoarthritis-a-case-report
#3
Kamya J Somaiya, Subrat Samal, Manali A Boob
Osteoarthritis (OA), the most common joint disease, lowers quality of life, restricts social activity participation, and results in incapacity. Osteoarthritis is characterised by changes in subchondral bone, meniscus degeneration, cartilage loss, and synovial inflammation. Physiotherapy plays a vital role in maintaining the stability of this disease. Various treatment approaches have been shown in numerous studies to be successful in improving the condition of individuals with osteoarthritis in the knee. We are presenting a case of a 47-year-old woman who had bilateral osteoarthritis in her knees...
February 2024: Curēus
https://read.qxmd.com/read/38532401/a-new-role-for-spinal-manual-therapy-and-for-chiropractic-part-i-weaknesses-and-threats
#4
JOURNAL ARTICLE
Søren Francis Dyhrberg O'Neill, Casper Nim, Dave Newell, Charlotte Leboeuf-Yde
Spinal manual therapy is central to chiropractic history, clinical practice, and professional identity. That chiropractors have developed an expertise in this domain has provided some considerable advantages. However, we contend it is also at the crux of the ideological schism that fractures the chiropractic profession. In this article, which is the first in a series of two, we discuss chiropractors' understanding and use of spinal manual therapy and do so with particular emphasis on what we see as weaknesses it creates and threats it gives rise to...
March 26, 2024: Chiropractic & Manual Therapies
https://read.qxmd.com/read/38531569/efficacy-and-safety-of-traditional-chinese-manual-therapy-tuina-in-patients-with-non-specific-chronic-low-back-pain-a-study-protocol-for-a-randomised-controlled-trial
#5
JOURNAL ARTICLE
Ben Cao, Sitong Fang, Zhiwei Wu, Xin Zhou, Lingjun Kong, Qingguang Zhu, Bowen Zhu, Cheng Tang, Min Fang
INTRODUCTION: Non-pharmacological interventions play a crucial role in the management of non-specific chronic low back pain (NSCLBP). One prime example is Tuina, a traditional Chinese manual therapy that incorporates pressing, kneading and rubbing techniques to alleviate physical discomfort and enhance overall well-being. It serves as a widely used technique in China and other East Asian countries. However, the effectiveness and safety of Tuina for managing NSCLBP have not been substantiated through rigorous clinical research...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38531463/consistent-spatial-lesion-symptom-patterns-a-comprehensive-analysis-using-triangulation-in-lesion-symptom-mapping-in-a-cohort-of-stroke-patients
#6
JOURNAL ARTICLE
Gabriel Ramirez-Garcia, Ximena Escutia-Macedo, Douglas J Cook, Talia Moreno-Andrade, Estefania Villarreal-Garza, Mario Campos-Coy, Guillermo Elizondo-Riojas, Fernando Gongora-Rivera, Eduardo A Garza-Villarreal, Juan Fernandez-Ruiz
INTRODUCTION: The relationship between brain lesions and stroke outcomes is crucial for advancing patient prognosis and developing effective therapies. Stroke is a leading cause of disability worldwide, and it is important to understand the neurological basis of its varied symptomatology. Lesion-symptom mapping (LSM) methods provide a means to identify brain areas that are strongly associated with specific symptoms. However, inner variations in LSM methods can yield different results...
March 24, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38531340/acupuncture-for-tinnitus-a-scoping-review-of-clinical-studies
#7
REVIEW
Keun Hee Lee, Min Hee Kim, Jaeho Kim, Hae Jeong Nam
BACKGROUND: Acupuncture treatment for tinnitus has received attention owing to its potential as an alternative to conventional treatment modalities. We conducted a scoping review to identify detailed information on acupuncture treatment methods used in clinical studies and to provide useful information for practitioners, patients, and researchers. METHODS:  Medline, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBPIA), and the China National Knowledge Infrastructure (CNKI) were searched from their inception to December 2023...
March 26, 2024: Complementary Medicine Research
https://read.qxmd.com/read/38529367/democratizing-pathological-image-segmentation-with-lay-annotators-via-molecular-empowered-learning
#8
JOURNAL ARTICLE
Ruining Deng, Yanwei Li, Peize Li, Jiacheng Wang, Lucas W Remedios, Saydolimkhon Agzamkhodjaev, Zuhayr Asad, Quan Liu, Can Cui, Yaohong Wang, Yihan Wang, Yucheng Tang, Haichun Yang, Yuankai Huo
Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced domain experts (e.g., pathologists). Moreover, such annotation is error-prone when differentiating fine-grained cell types (e.g., podocyte and mesangial cells) via the naked human eye. In this study, we assess the feasibility of democratizing pathological AI deployment by only using lay annotators (annotators without medical domain knowledge)...
October 2023: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://read.qxmd.com/read/38529031/cervical-impairments-in-subjects-with-migraine-or-tension-type-headache-an-observational-study
#9
JOURNAL ARTICLE
Jose Ángel Del Blanco Muñiz, Alberto Sánchez Sierra, Arturo Ladriñán Maestro, Roberto Ucero Lozano, María Dolores Sosa-Reina, Daniel Martín Vera
OBJECTIVE: The aim of this investigation was to compare the thickness of the deep local muscles in the neck region, as well as local and widespread sensitivity and functionality, between individuals with migraine, Tension-Type Headache (TTH), and healthy controls. To date, we know that the onset of migraine and TTH share similar pathophysiological pathways. Nevertheless, there may be some anatomical and functional differences which would explain why clinicians may obtain variable results when treating both pathological entities with similar or equal approaches...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38528470/evaluating-the-efficacy-of-different-volume-resuscitation-strategies-in-acute-pancreatitis-patients-a-systematic-review-and-meta-analysis
#10
JOURNAL ARTICLE
Roopa Kumari, Fnu Sadarat, Sindhu Luhana, Om Parkash, Abhi Chand Lohana, Zubair Rahaman, Hong Yu Wang, Yaqub N Mohammed, Sanjay Kirshan Kumar, Subhash Chander
INTRODUCTION: Acute pancreatitis poses a significant health risk due to the potential for pancreatic necrosis and multi-organ failure. Fluid resuscitation has demonstrated positive effects; however, consensus on the ideal intravenous fluid type and infusion rate for optimal patient outcomes remains elusive. METHODS: A comprehensive literature search was conducted using PubMed, Embase, the Cochrane Library, Scopus, and Google Scholar for studies published between 2005 and January 2023...
March 25, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38525811/automated-tumor-immunophenotyping-predicts-clinical-benefit-from-anti-pd-l1-immunotherapy
#11
JOURNAL ARTICLE
Xiao Li, Jeffrey Eastham, Jennifer M Giltnane, Wei Zou, Andries Zijlstra, Evgeniy Tabatsky, Romain Banchereau, Ching-Wei Chang, Barzin Y Nabet, Namrata S Patil, Luciana Molinero, Steve Chui, Maureen Harryman, Shari Lau, Linda Rangell, Yannick Waumans, Mark Kockx, Darya Orlova, Hartmut Koeppen
Cancer immunotherapy has transformed the clinical approach to patients with malignancies, as profound benefits can be seen in a subset of patients. To identify this subset, biomarker analyses increasingly focus on phenotypic and functional evaluation of the tumor microenvironment to determine if density, spatial distribution, and cellular composition of immune cell infiltrates can provide prognostic and/or predictive information. Attempts have been made to develop standardized methods to evaluate immune infiltrates in the routine assessment of certain tumor types; however, broad adoption of this approach in clinical decision-making is still missing...
March 25, 2024: Journal of Pathology
https://read.qxmd.com/read/38525785/the-majority-of-clinical-trials-assessing-mobilization-and-manipulation-for-neck-pain-lack-a-pragmatic-approach-a-systematic-review-of-174-trials
#12
REVIEW
Kyle A Cottone, Matthew R Schumacher, Jodi L Young, Daniel I Rhon
BACKGROUND: Disorders of the cervical spine are some of the costliest musculoskeletal conditions to manage globally. Joint mobilization and manipulation have been shown to be an effective treatment for neck pain. However, the generalizability and clinical translation depends on the nature of the trial designs that inform its use. The extent to which randomized control trials (RCTs) assessing manual therapy treatments for cervical spine disorders fall on the efficacy (explanatory) -effectiveness (pragmatic) spectrum often informs how the findings are translated into clinical practice...
March 25, 2024: Journal of Manual & Manipulative Therapy
https://read.qxmd.com/read/38524766/assessing-the-real-world-long-term-impact-of-lemborexant-on-sleep-quality-in-a-home-based-clinical-study
#13
Seiko Miyata, Kunihiro Iwamoto, Ippei Okada, Akihiro Fujimoto, Yuki Kogo, Daisuke Mori, Manabu Amano, Nao Matsuyama, Kazuki Nishida, Masahiko Ando, Toshiaki Taoka, Shinji Naganawa, Norio Ozaki
PURPOSE: Both subjective and objective evaluations are essential for the treatment of insomnia. Lemborexant has been shown to be effective in the long-term based solely on a subjective basis, and no long-term objective measures have been evaluated under natural sleep conditions. Small, lightweight sleep electroencephalogram (EEG) monitor was used, instead of polysomnography, to objectively evaluate sleep at home 4 and 12 weeks after lemborexant treatment. PATIENTS AND METHODS: Adults and elderly subjects with insomnia disorder, per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, were enrolled in this open-label, single-arm, single-center trial...
2024: Nature and Science of Sleep
https://read.qxmd.com/read/38523203/is-there-a-role-for-platelet-rich-plasma-injection-in-vulvar-lichen-sclerosus-a-self-controlled-pilot-study
#14
JOURNAL ARTICLE
Veronica Boero, Giulia Emily Cetera, Carlotta Caia, Stefania Villa, Tiziana Montemurro, Massimiliano Brambilla, Ermelinda Monti, Maria Iorio, Edgardo Somigliana, Paolo Vercellini, Daniele Prati
BACKGROUND: Owing to the evidence that as many as 30-40% of patients with vulvar lichen sclerosus (VLS) fail to report a remission of symptoms with first-line corticosteroid treatment (TCS), especially as what regards dyspareunia, we aimed to analyze patients' satisfaction following vulvar injection of autologous platelet-rich plasma (PRP). This is intended as an adjunctive treatment, to be used following TCS, and appears to promote tissue repair. It may also possibly have immunomodulatory proprieties...
March 24, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38521695/development-of-an-mr-guided-focused-ultrasound-mrgfus-lesioning-approach-for-the-fornix-in-the-rat-brain
#15
JOURNAL ARTICLE
Carena Cornelssen, Allison Payne, Dennis L Parker, Matthew Alexander, Robb Merrill, Sharayu Senthilkumar, Jacob Christensen, Karen S Wilcox, Henrik Odéen, John D Rolston
OBJECTIVE: High-intensity magnetic resonance-guided focused ultrasound (MRgFUS) is a non-invasive therapy to lesion brain tissue, used clinically in patients and pre-clinically in several animal models. Challenges with focused ablation in rodent brains can include skull and near-field heating and accurately targeting small and deep brain structures. We overcame these challenges by creating a novel method consisting of a craniectomy skull preparation, a high-frequency transducer (3 MHz) with a small ultrasound focal spot, a transducer positioning system with an added manual adjustment of ∼0...
March 22, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38520876/use-of-cupping-therapy-in-musculoskeletal-disorders-a-cross-sectional-study-on-the-profile-training-and-practice-of-brazilian-physical-therapists
#16
JOURNAL ARTICLE
Wesley Rodrigo Costa Rios, Hugo Jario Almeida Silva, Nayara Silva Pontes, André Pontes-Silva, Mariana Arias Avila, Bruno Tirotti Saragiotto, José Jailson de Almeida Júnior, Germanna Medeiros Barbosa, Marcelo Cardoso de Souza
INTRODUCTION: Cupping therapy is a widely used technique in Brazilian physical therapy for the treatment of musculoskeletal disorders. However, there is limited scientific evidence to support its effectiveness. OBJECTIVE: To investigate the profile, training, clinical practice, and scientific updates of Brazilian Physical Therapists who use cupping therapy as a therapeutic resource for musculoskeletal disorders. METHODS: A cross-sectional study was conducted through an online questionnaire, including 646 Physical Therapists who use cupping therapy in their practice...
March 18, 2024: Musculoskeletal Science & Practice
https://read.qxmd.com/read/38520604/adherence-and-persistence-to-basal-insulin-among-people-with-type%C3%A2-2-diabetes-in-europe-a-systematic-literature-review-and-meta-analysis
#17
REVIEW
Esteban J Gimeno, Mette Bøgelund, Sara Larsen, Anna Okkels, Signe B Reitzel, Hongye Ren, Domingo Orozco-Beltran
INTRODUCTION: Diabetes is associated with a number of complications, particularly if glycaemic targets are not achieved. Glycaemic control is highly linked to treatment persistence and adherence. To understand the burden of poor persistence and adherence, this systematic literature review identified existing evidence regarding basal insulin adherence/non-adherence and persistence/non-persistence among people with diabetes in Western Europe (defined as the UK, France, Spain, Switzerland, the Netherlands, Ireland, Austria, Portugal, Denmark, Norway, Sweden, Finland, Italy, Germany, Iceland and Belgium)...
March 23, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38518624/the-emerging-role-of-biostimulators-as-an-adjunct-in-facial-rejuvenation-a-systematic-review
#18
REVIEW
Sean M Fisher, Zachary Borab, David Weir, Rod J Rohrich
INTRODUCTION: Facial aging has long been an area of focus in esthetic surgery. It is the consequence of physiologic and environmental factors, with a trend toward non-surgical modalities. Although volume augmentation has long been a focus of non-surgical facial rejuvenation, there is emerging interest in the use of biostimulators to induce physiologic changes in the skin. This article aimed to provide an overview of this class of therapies. METHODS: A systematic review regarding the clinical use of biostimulatory agents including platelet-rich plasma (PRP), platelet-rich fibrin (PRF), poly-L-lactic acid (PLLA) and calcium hydroxylapatite (CaHA) in facial rejuvenation was performed using PubMed databases...
March 6, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/38517831/influence-of-brick-laying-height-on-biomechanical-load-in-masons-cross-sectional-field-study-with-technical-measurements
#19
JOURNAL ARTICLE
Mikkel Brandt, Rúni Bláfoss, Markus Due Jakobsen, Afshin Samani, Jeppe Z N Ajslev, Pascal Madeleine, Lars L Andersen
BACKGROUND: Work-related musculoskeletal disorders (WMSDs) located in the low back and neck/shoulder regions are major concerns for both workers, workplaces, and society. Masons are prone to WMSD, because their work is characterized by repetitive work and high physical workload. However, the knowledge on the physical workload during bricklaying is primarily based on subjective measurements. OBJECTIVE: This cross-sectional field study with technical measurements aimed to quantify physical workload in terms of muscular activity and degree of forward bending during bricklaying at different working heights among masons, i...
March 19, 2024: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/38516329/fully-automated-mr-based-virtual-biopsy-of-primary-cns-lymphomas
#20
JOURNAL ARTICLE
Vicky Parmar, Johannes Haubold, Luca Salhöfer, Mathias Meetschen, Karsten Wrede, Martin Glas, Maja Guberina, Tobias Blau, Denise Bos, Anisa Kureishi, René Hosch, Felix Nensa, Michael Forsting, Cornelius Deuschl, Lale Umutlu
BACKGROUND: Primary central nervous system lymphomas (PCNSL) pose a challenge as they may mimic gliomas on magnetic resonance imaging (MRI) imaging, compelling precise differentiation for appropriate treatment. This study focuses on developing an automated MRI-based workflow to distinguish between PCNSL and gliomas. METHODS: MRI examinations of 240 therapy-naive patients (141 males and 99 females, mean age: 55.16 years) with cerebral gliomas and PCNSLs (216 gliomas and 24 PCNSLs), each comprising a non-contrast T1-weighted, fluid-attenuated inversion recovery (FLAIR), and contrast-enhanced T1-weighted sequence were included in the study...
2024: Neuro-oncology advances
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