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https://www.readbyqxmd.com/read/28702205/association-of-arsenobetaine-with-beta-cell-function-assessed-by-homeostasis-model-assessment-homa-in-nondiabetic-koreans-data-from-the-fourth-korea-national-health-and-nutrition-examination-survey-knhanes-2008-2009
#1
Kiook Baek, Namhoon Lee, Insung Chung
BACKGROUND: Arsenic is known as an endocrine disruptor that people are exposed to through various sources such as drinking water and indigestion of marine products. Although some epidemiological and animal studies have reported a correlation between arsenic exposure and diabetes development, there are limited studies regarding the toxic effects of organic arsenic including arsenobetaine on the human body. Here, we analyzed the association between urine arsenobetaine and the homeostasis model assessment of β-cell function (HOMA-β), which is an index for predicting diabetes development and reflecting the function of pancreatic β-cells...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28700039/sexual-dysfunction-in-females-with-depression-a-cross-sectional-study
#2
Krishnankutty Sreelakshmy, Rajmohan Velayudhan, Deepak Kuriakose, Rema Nair
Introduction: Female sexual dysfunction (FSD) in depression albeit common is strikingly understudied. The condition, if addressed properly, can be readily cured, improving the quality of life of the patient. Methods: A consecutive sample of drug-naïve married female patients with depression was assessed. Depression was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Depression severity was assessed using the Hamilton Depression Rating Scale (HAM-D), and sexual dysfunction, the Female Sexual Function Index (FSFI)...
April 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28685227/postoperative-sexual-functioning-in-total-versus-subtotal-laparoscopic-hysterectomy-what-do-women-expect
#3
Sebastian Berlit, Stefanie Lis, Sven Jürgens, Olaf Buchweitz, Amadeus Hornemann, Marc Sütterlin, Benjamin Tuschy
PURPOSE: To evaluate sexual functioning and expected changes in sexual functioning in women with planned total versus subtotal laparoscopic hysterectomy. METHODS: A total of 120 women undergoing laparoscopic hysterectomy were preoperatively enrolled in this study with a cross-sectional design. Full data sets were available for 112 patients, so that 56 patients with planned total laparoscopic hysterectomy (TLH) and 56 women with planned laparoscopic supracervical hysterectomy (LASH) were preoperatively assessed...
July 6, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28682869/the-impact-of-systemic-lupus-erythematosus-on-women-s-sexual-functioning-a-systematic-review-and-meta-analysis
#4
REVIEW
Rulan Yin, Bin Xu, Lin Li, Ting Fu, Lijuan Zhang, Qiuxiang Zhang, Xia Li, Biyu Shen
BACKGROUND: A number of studies have reported the relationship between women's sexual problems and systemic lupus erythematosus (SLE). However, the results are contradictory. The objective of this paper was to explore the impact of SLE on women's sexual function. METHODS: PubMed, Web of Science, CNKI Scholar, VIP and WanFang databases were searched up to April 2017. Studies evaluating the impact of SLE on women's sexual function with the use of Female Sexual Function Index (FSFI) scoring system were included...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28677142/assessment-of-sexually-related-personal-distress-accompanying-premenopausal-sexual-dysfunction-with-an-arabic-version-of-the-female-sexual-distress-scale
#5
Magdy R Ahmed, Mohamed M Shaaban, Heba K Meky
OBJECTIVE: To assess sexually related personal distress among premenopausal women with female sexual dysfunction (FSD) via a validated Arabic version of the Female Sexual Distress Scale (FSDS). METHODS: A cross-sectional study was conducted among women attending Suez Canal University Hospital, Egypt, between May 2015 and July 2016. In a pilot study to evaluate test-retest reliability and internal consistency, 42 sexually active premenopausal women (aged ≥20 years) completed the Arabic FSDS at recruitment and 2 weeks later...
July 5, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28675768/experimental-evolution-reveals-differences-between-phenotypic-and-evolutionary-responses-to-population-density
#6
Kathryn B McNamara, Leigh W Simmons
Group living can select for increased immunity, given the heightened risk of parasite transmission. Yet, it also may select for increased male reproductive investment, given the elevated risk of female multiple mating. Trade-offs between immunity and reproduction are well documented. Phenotypically, population density mediates both reproductive investment and immune function in the Indian meal moth, Plodia interpunctella. However, the evolutionary response of populations to these traits is unknown. We created two replicated populations of P...
July 4, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28673436/a-survey-of-female-sexual-functioning-in-the-general-dutch-population
#7
Ellen A G Lammerink, Geertruida H de Bock, Astrid Pascal, Andre P van Beek, Alfons C M van den Bergh, Margriet G A Sattler, Marian J E Mourits
BACKGROUND: After the diagnosis and treatment of disease, a major barrier to research on psychosexual functioning is the lack of a consistent estimate for the prevalence of female sexual dysfunction in the general population. AIM: To clarify the prevalence of age-related female sexual functioning in the general population. METHODS: A sample was compiled by random selection of women from the general population in the northern part of the Netherlands and was categorized by age...
July 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28666836/flibanserin-efficacy-and-safety-in-premenopausal-women-with-generalized-acquired-hypoactive-sexual-desire-disorder
#8
REVIEW
William A Fisher, Robert E Pyke
INTRODUCTION: Flibanserin is a postsynaptic 5-HT-1A agonist and 5-HT-2A antagonist for the treatment of generalized acquired hypoactive sexual desire disorder in premenopausal women. AIM: To review and evaluate the efficacy and safety of flibanserin. METHODS: We review and critique the appropriateness of the co-primary and secondary end points used in the flibanserin pivotal trial research program. We review the efficacy and safety parameters of this drug based on the published literature and related sources...
June 27, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28665994/a-novel-role-of-kr%C3%A3-ppel-like-factor-4-in-zhikong-scallop-chlamys-farreri-during-spermatogenesis
#9
Dandan Yang, Zhifeng Zhang, Shaoshuai Liang, Qiankun Yang, Yingrui Wang, Zhenkui Qin
Krüppel-like factor 4 (KLF4) is a kind of zinc finger transcription factor, which is involved in terminal differentiation of epithelial cells and reprogramming of somatic cells to induced pluripotent stem (iPS) cells in mammals. In the present study, we identified a full-length cDNA of Klf4 in Zhikong scallop Chamys farreri (Cf-Klf4) and found that Cf-Klf4 presented a sexual dimorphic expression characteristic in C. farreri gonads. Cf-Klf4 expression was significantly higher in testes than in ovaries from growing stage to mature stage detected by quantitative real-time PCR, and was located in male gametes, except for spermatozoa during spermatogenesis through in situ hybridization and immunohistochemistry, while no positive signal was visible in female gametes during oogenesis...
2017: PloS One
https://www.readbyqxmd.com/read/28660406/evaluation-of-potentially-prolactin-related-adverse-events-and-sexual-maturation-in-adolescents-with-schizophrenia-treated-with-paliperidone-extended-release-er-for-2-years-a-post-hoc-analysis-of-an-open-label-multicenter-study
#10
Srihari Gopal, Rosanne Lane, Isaac Nuamah, Margaret Copenhaver, Jaskaran Singh, David Hough, Mark Bach, Adam Savitz
BACKGROUND: Elevated prolactin levels (hyperprolactinemia) are a frequent adverse effect of antipsychotic medications, especially in young populations. Prolonged hyperprolactinemia may affect sexual functioning and the onset and progression of puberty. OBJECTIVE: This study assessed potentially prolactin-related treatment-emergent adverse events (PPRL-TEAEs) and sexual maturation during long-term treatment of adolescents with paliperidone extended-release (ER). METHODS: This post hoc analysis of a 2-year open-label multicenter study (NCT00488319) included patients of either sex aged 12-17 years at study enrollment, diagnosed with schizophrenia (Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV]) for ≥1 year, who had received one or more adequate antipsychotic treatment prior to enrollment but had not responded sufficiently...
June 28, 2017: CNS Drugs
https://www.readbyqxmd.com/read/28657769/monurelle-biogel-%C3%A2-vaginal-gel-in-the-treatment-of-vaginal-dryness-in-postmenopausal-women
#11
R E Nappi, A Cagnacci, A M Becorpi, C Nappi, A M Paoletti, M Busacca, S Martella, M Bellafronte, Z Tredici, C Di Carlo, V Corda, M Vignali, M Bagolan, M Sardina
OBJECTIVES: To evaluate efficacy, tolerability and safety of Monurelle Biogel(®) vaginal gel for treatment of vaginal dryness. METHODS: Multicenter, national, randomized, controlled vs. no-treatment, open-label study. Ninety-five postmenopausal women were randomized (48 to Monurelle Biogel(®) and 47 to no treatment). Primary endpoint was the change of Verbal Rating Scale (VRS) total score of vaginal atrophy (VA) symptoms after 8-week treatment. The main secondary endpoints were VRS single-item score, Vaginal Health Index (VHI) score, Maturation Index (MI), Female Sexual Function Index (FSFI), and Female Sexual Distress Scale-Revised (FSDS-R)...
June 28, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28652167/effects-of-urinary-incontinence-subtypes-on-women-s-sexual-function-and-quality-of-life
#12
Salvatore Caruso, Roberta Brescia, Maria Grazia Matarazzo, Giuliana Giunta, Agnese Maria Chiara Rapisarda, Antonio Cianci
OBJECTIVES: To evaluate the effects of different subtypes of UI on sexual function and quality of life (QoL). MATERIALS AND METHODS: 93 women with UI were enrolled in the observational study. By the urodynamic findings, 32 women (34.5 %) were diagnosed with stress urinary incontinence (SUI), 35 (37.6%) with urgency urinary incontinence (UUI), and 26 (27.9%) with mixed urinary incontinence (MUI). The SF-36 questionnaire was used to investigate the quality of life (QoL), and the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale (FSDS) questionnaires were used to study the sexual function and sexaul distress, respectively...
June 23, 2017: Urology
https://www.readbyqxmd.com/read/28647305/impact-of-asthma-on-the-sexual-functioning-of-patients-a-case-control-study
#13
José Gregorio Soto Campos, Josefa Rojas Villegas, Alicia Padilla Galo, Nuria Marina Malanda, Juan Luis Garcia Rivero, Celia Pinedo Sierra, Mercedes Garcia Salmones, Carmen Cabrera Galán, Esperanza Segura Molina, Vicente Plaza
INTRODUCTION: Sexual limitations play an important role in the quality of life of patients with chronic diseases. Very limited information is available on the impact of asthma on the sexual functioning of these individuals. MATERIALS AND METHODS: Cross-sectional, observational, multicenter study. Asthma patients and healthy individuals were recruited. All subjects participated in an interview in which demographic and clinical data were recorded, and completed the Goldberg Anxiety-Depression Scale (GADS) to evaluate the presence of concomitant psychiatric disease...
June 21, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28643025/effects-of-bariatric-surgery-on-pelvic-floor-disorders-in-obese-women-a-meta-analysis
#14
REVIEW
Wenqing Lian, Yiqun Zheng, Hongxing Huang, Lianghua Chen, Bin Cao
PURPOSE: Obesity is an established risk factor for pelvic floor disorders (PFD) but the effects of bariatric surgery on PFD are uncertain. This meta-analysis was conducted to evaluate the effects of bariatric surgery on PFD in obese women. METHODS: A systematic search of PubMed, Cochrane Library, CNKI and CBM databases up to October 2016 was performed, and studies reporting pre-operative and post-operative outcomes in obese women undergoing bariatric surgery were included...
August 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28638707/sexual-dysfunction-in-female-patients-with-relapsing-remitting-multiple-sclerosis
#15
Pawel Bartnik, Aleksandra Wielgoś, Joanna Kacperczyk, Katarzyna Pisarz, Iwona Szymusik, Aleksandra Podlecka-Piętowska, Beata Zakrzewska-Pniewska, Miroslaw Wielgoś
INTRODUCTION: Sexual dysfunction (SD) is one of the common symptoms of multiple sclerosis (MS) and is often underdiagnosed, especially in women. Relapsing-remitting multiple sclerosis (RRMS) is the most widespread form of the disease, but the data on SD occurrence in this particular group of patients is limited. The aim of the study was to analyze the associations between demographic factors, symptoms and signs of MS, psychiatric comorbidities and SD in female patients with RRMS. MATERIAL & METHODS: A subgroup of 86 sexually active women with RRMS out of 218 total MS respondents was analyzed...
June 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28638288/effects-of-immunomodulators-and-biologic-agents-on-sexual-health-in-patients-with-inflammatory-bowel-disease
#16
Ozdemir Kanar, Andrew C Berry, Rahman Nakshabendi, Ann Joo Lee, Petra Aldridge, Travis Myers, Emely Eid
BACKGROUND: Although much knowledge has been gained regarding the medical and surgical management of inflammatory bowel disease (IBD), a paucity of information is available on the psychosexual issues related to IBD. The aim of this study was to evaluate the sexual health of patients with IBD who were taking immunomodulators and/or biologic agents vs patients with IBD who were not on that medication regimen. METHODS: All study participants completed a validated sexual health questionnaire, the Female Sexual Function Index or the International Index of Erectile Function, to assess their subjective perception of the effect of IBD on the different domains of sexual function during the prior 1-month time period...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28635530/the-effect-of-voluntary-termination-of-pregnancy-on-female-sexual-and-emotional-well-being-in-different-age-groups
#17
Erika Limoncin, Angela D'Alfonso, Claudia Corallino, Vincenza Cofini, Giovanna Di Febbo, Giacomo Ciocca, Daniele Mollaioli, Felice Patacchiola, Emmanuele A Jannini, Gaspare Carta
INTRODUCTION: To evaluate the impact of voluntary termination of pregnancy (VTOP) on the psycho-sexological well-being of females before/six months after the abortion. METHODS: A sample of 194 women was recruited from three obstetrics and gynaecological divisions. The women were evaluated for the variables "sexual functioning" with the Female Sexual Function Index (FSFI), "depression" with the Beck Depression Inventory (BDI-II), and "anxiety state" with the Self-Rating Anxiety Scale (SAS) at time 0 (the beginning of the abortion procedure) and time 1 (six months after the abortion)...
February 15, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28635309/rheumatoid-arthritis-is-associated-with-negatively-variable-impacts-on-domains-of-female-sexual-function-evidence-from-a-systematic-review-and-meta-analysis
#18
Qiuxiang Zhang, Congcong Zhou, Haoyang Chen, Qian Zhao, Lin Li, Yafei Cui, Biyu Shen
To systematically review the literature to identify the impact of rheumatoid arthritis (RA) on specific female sexual function domains. A meta-analysis was performed and the related literature were searched in MEDLINE, EMBASE, Cochrane Library, CNKI, CBM and Web of Science databases, and in reference lists of articles and systematic reviews. Score of the Female Sexual Function Index (FSFI) was used as the outcome measurement, and mean differences (MD) with 95% confidence intervals (CI) were calculated. Five studies were included, including 346 women with RA and 237 healthy female controls...
June 21, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28632793/the-prevalence-and-correlates-of-low-sexual-functioning-in-women-on-hemodialysis-a-multinational-cross-sectional-study
#19
Valeria Saglimbene, Patrizia Natale, Suetonia Palmer, Marco Scardapane, Jonathan C Craig, Marinella Ruospo, Letizia Gargano, Giuseppe Lucisano, Marietta Török, Eduardo Celia, Rubén Gelfman, Anna Bednarek-Skublewska, Jan Dulawa, Paul Stroumza, Miguel Leal, Domingo Del Castillo, Angelo Marco Murgo, Staffan Schon, Charlotta Wollheim, Jörgen Hegbrant, Giovanni F M Strippoli
Sexual dysfunction may affect 80% of women in hemodialysis. However the specific patterns and clinical correlates of sexual functioning remain poorly described. The aim of this study was to assess prevalence and correlates of the individual domains of sexual functioning in women treated with hemodialysis. We recruited, into this multinational cross-sectional study, women treated with long-term hemodialysis (Collaborative Working Group on Depression and Sexual dysfunction in Hemodialysis study). Self-reported domains of sexual functioning were assessed by the Female Sexual Function Index, which is routinely administered within the network of dialysis patients followed by the working group...
2017: PloS One
https://www.readbyqxmd.com/read/28628972/urinary-sexual-steroids-associated-with-bisphenol-a-bpa-exposure-in-the-early-infant-stage-preliminary-results-from-a-daishan-birth-cohort
#20
Heng Wang, Liangpo Liu, Jianyue Wang, Zhendong Tong, Jianbo Yan, Tongjie Zhang, Ying Qin, Tingting Jiang, Jianwen She, Heqing Shen
BACKGROUND: Many surveys have shown that older children are ubiquitously exposed to bisphenol A (BPA), and many laboratory studies have shown that BPA exposure has adverse effects related to estrogenic disruption, whereas the evidence in infants has not yet been observed. METHODS: Women in early pregnancy were recruited by the Maternal and Child Health and Family Planning Service Center, Daishan, China, from March 2012 to December 2014. After delivery, urine samples were collected from the diapers of 59 infants (0 to 6months of age)...
June 13, 2017: Science of the Total Environment
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