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Toddler development

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https://www.readbyqxmd.com/read/29468770/pessary-for-preterm-birth-prevention-in-twin-pregnancy-with-short-cervix-3-year-follow-up-study
#1
Janneke van 't Hooft, Johanna H van der Lee, Brent C Opmeer, Aleid G van Wassenaer-Leemhuis, Anneloes L van Baar, Dick J Bekedam, Leonie J P Steenis, Sophie Liem, Ewoud Schuit, Cuny Cuijpers, Elise Bleeker, Margot E Vinke, Noor Simons, Irene M de Graaf, Ben Willem J Mol, Cornelieke van de Beek
OBJECTIVE: We recently found in a randomized clinical trial (ProTWIN) that cervical pessary prevented preterm birth and improved neonatal outcome in women with a multiple pregnancy and a cervical length (CL) <38mm. In this follow-up study we evaluated long-term developmental outcomes in the offspring of these women at three years corrected age. METHODS: We conducted a follow-up study of the ProTWIN trial, a trial in which between 2009 and 2012 asymptomatic women with a multiple pregnancy had been randomized to pessary or no pessary...
February 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29468696/i-introduction
#2
Caroline Floccia, Thomas D Sambrook, Claire Delle Luche, Rosa Kwok, Jeremy Goslin, Laurence White, Allegra Cattani, Emily Sullivan, Kirsten Abbot-Smith, Andrea Krott, Debbie Mills, Caroline Rowland, Judit Gervain, Kim Plunkett
The majority of the world's children grow up learning two or more languages. The study of early bilingualism is central to current psycholinguistics, offering insights into issues such as transfer and interference in development. From an applied perspective, it poses a universal challenge to language assessment practices throughout childhood, as typically developing bilingual children usually underperform relative to monolingual norms when assessed in one language only. We measured vocabulary with Communicative Development Inventories for 372 24-month-old toddlers learning British English and one Additional Language out of a diverse set of 13 (Bengali, Cantonese, Dutch, French, German, Greek, Hindi-Urdu, Italian, Mandarin, Polish, Portuguese, Spanish, and Welsh)...
March 2018: Monographs of the Society for Research in Child Development
https://www.readbyqxmd.com/read/29463137/evaluation-of-the-body-mass-index-bmi-in-children-born-to-organ-transplant-recipients
#3
Joanna Schreiber-Zamora, Monika Szpotanska-Sikorska, Natalia Czaplinska, Agnieszka Drozdowska-Szymczak, Bronisława Pietrzak, Mirosław Wielgos, Bozena Kociszewska-Najman
BACKGROUND: Overweight and obesity are one of the most serious clinical health problems. Until now, the long-term development of children born to mothers after transplantation is unknown. In this study, we attempted to present the analysis of the prevalence of overweight in the population of mothers after kidney or liver transplants. METHODS: A comparison of body mass index (BMI) measurements performed in 61 children of kidney transplant women (study group) and 64 children born to healthy mothers (control group)...
February 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29462926/do-current-fortification-and-supplementation-programs-assure-adequate-intake-of-fat-soluble-vitamins-in-belgian-infants-toddlers-pregnant-women-and-lactating-women
#4
Isabelle Moyersoen, Carl Lachat, Koenraad Cuypers, Karin De Ridder, Brecht Devleesschauwer, Jean Tafforeau, Stefanie Vandevijvere, Margot Vansteenland, Bruno De Meulenaer, John Van Camp, Herman Van Oyen
Abstracts: Adequate intakes of fat-soluble vitamins are essential to support the growth and development of the foetus, the neonate, and the young child. By means of an online self-administered frequency questionnaire, this study aimed to evaluate the intake of vitamins A, D, E, and K in Belgian infants ( n = 455), toddlers ( n = 265), pregnant women ( n = 161), and lactating women ( n = 165). The contribution of foods, fortified foods, and supplements on the total intake was quantified. 5% of toddlers, 16% of pregnant women, and 35% of lactating women had an inadequate vitamin A intake...
February 16, 2018: Nutrients
https://www.readbyqxmd.com/read/29457574/motherese-affect-and-vocabulary-development-dyadic-communicative-interactions-in-infants-and-toddlers
#5
Shruti Dave, Ann M Mastergeorge, Lesley B Olswang
Responsive parental communication during an infant's first year has been positively associated with later language outcomes. This study explores responsivity in mother-infant communication by modeling how change in guiding language between 7 and 11 months influences toddler vocabulary development. In a group of 32 mother-child dyads, change in early maternal guiding language positively predicted child language outcomes measured at 18 and 24 months. In contrast, a number of other linguistic variables - including total utterances and non-guiding language - did not correlate with toddler vocabulary development, suggesting a critical role of responsive change in infant-directed communication...
February 19, 2018: Journal of Child Language
https://www.readbyqxmd.com/read/29448893/arsenic-species-in-rice-and-rice-based-products-consumed-by-toddlers-in-switzerland
#6
Roxane Guillod-Magnin, Beat J Brüschweiler, Rafael Aubert, Max Haldimann
Inorganic arsenic (iAs) is a contaminant present in food, especially in rice and rice-based products. Toxicity of arsenic compounds (As) depends on species and oxidative state. Inorganic arsenic species, such as arsenite (As(III)) and arsenate (As(V)), are more bioactive and toxic than organic arsenic species, like methylarsonic acid (MMA(V)) and dimethylarsinic acid (DMA(V)) or arsenosugars and arsenobetaine. An ion chromatography-inductively coupled plasma-mass spectroscopy (IC-ICP-MS) method was developed to separate the four following arsenic anions: As(III), As(V), MMA(V) and DMA(V)...
February 16, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29447804/long-term-follow-up-with-mention-of-complications-in-pediatric-microvascular-mandibular-reconstruction
#7
Kenneth Akakpo, Christopher Iobst, Matthew Old, Jonathan Grischkan
The fibular free flap has become the gold standard for mandibular reconstruction. Despite its vast array of benefits, this procedure has the potential for several complications. In the pediatric setting, the immature skeleton sets the stage for an increased risk of future skeletal abnormalities, both in the jaw, and in the donor site. Herein we describe the case of a toddler who underwent mandibular reconstruction using a fibula free flap and, years later, subsequently developed ankle instability as a result of residual fibula migration...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29433948/adherence-barriers-in-pediatric-epilepsy-from-toddlers-to-young-adults
#8
Ana M Gutierrez-Colina, Aimee W Smith, Constance A Mara, Avani C Modi
OBJECTIVE: The objectives of this study were to examine the continuity of adherence barriers across stages of development in pediatric epilepsy and to assess the differential influence of barriers on several important clinical outcomes from early childhood to young adulthood, including adherence, seizures, and health-related quality of life (HRQOL). METHOD: A developmentally representative sample of youth 2-25years with epilepsy was obtained by combining data from five different studies...
February 9, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29429197/-early-childhood-development-and-risk-factors-in-rural-china-a-cohort-study
#9
Y Cui, J Q Gao, A Yue, L Tang, R F Luo, Rozelle Scott
Objective: To investigate the development status and risk factors of infants and toddlers in rural China. Methods: In this cohort study, 603 infants (6-12 months of age, Phase Ⅰ) in the rural areas of QinLing-Bashan (Qin-Ba) in Shaanxi were recruited in the control group that received no intervention from April 2013 to October 2015. Three follow-up visits were performed every six months (Phase Ⅱ(12-18 months of age), Phase Ⅲ (18-24 months of age) and Phase Ⅳ(24-30 months of age)). In all the 4 phases (Ⅰ-Ⅳ), general data of the children and the families were collected by questionnaires, early childhood growth and development were assessed by door to door visits, children's hemoglobin levels were determined by laboratory tests, and the cognitive and motor development screening was conducted by the Bayley Scales of Infant and Toddler Development...
February 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29427671/prospective-associations-between-toddler-televiewing-and-subsequent-lifestyle-habits-in-adolescence
#10
Isabelle Simonato, Michel Janosz, Isabelle Archambault, Linda S Pagani
BACKGROUND: Watching television is a common pastime for very young children. High exposure may negatively influence physical and mental health outcomes. Not much is known about how early exposure relates to lifestyle choices in adolescence. OBJECTIVE: To estimate how toddler televiewing is subsequently associated with lifestyle indicators at adolescence. METHODS: Participants are 986 girls and 999 boys from the Quebec Longitudinal Study of Child Development birth cohort (Canada)...
February 7, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29426320/supporting-play-exploration-and-early-developmental-intervention-versus-usual-care-to-enhance-development-outcomes-during-the-transition-from-the-neonatal-intensive-care-unit-to-home-a-pilot-randomized-controlled-trial
#11
Stacey C Dusing, Tanya Tripathi, Emily C Marcinowski, Leroy R Thacker, Lisa F Brown, Karen D Hendricks-Muñoz
BACKGROUND: While therapy services may start in the Neonatal Intensive Care Unit (NICU) there is often a gap in therapy after discharge. Supporting Play Exploration and Early Development Intervention (SPEEDI) supports parents, helping them build capacity to provide developmentally supportive opportunities starting in the NICU and continuing at home. The purpose of this single blinded randomized pilot clinical trial was to evaluate the initial efficacy of SPEEDI to improve early reaching and exploratory problem solving behaviors...
February 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29421831/amplitude-integrated-eeg-and-cerebral-near-infrared-spectroscopy-in-cooled-asphyxiated-infants
#12
C K Niezen, A F Bos, D A Sival, L C Meiners, H J Ter Horst
OBJECTIVE:  To assess the predictive value of amplitude-integrated electroencephalography EEG (aEEG) and near-infrared spectroscopy (NIRS) during therapeutic hypothermia. PATIENTS AND METHODS:  We studied 39 cooled, asphyxiated infants. We assessed aEEG and calculated mean regional cerebral oxygen saturation (rcSO2) during and after treatment. At 30 months, we performed a neurological examination and administered the Bayley Scales of Infant and Toddler Development, 3rd edition...
February 8, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29412514/effects-of-parent-implemented-early-start-denver-model-intervention-on-chinese-toddlers-with-autism-spectrum-disorder-a-non-randomized-controlled-trial
#13
Bingrui Zhou, Qiong Xu, Huiping Li, Ying Zhang, Yi Wang, Sally J Rogers, Xiu Xu
To evaluate the effects of a 26-week, high-intensity, parent-implemented Early Start Denver Model (P-ESDM) intervention on developmental outcomes, severity of autism spectrum disorder (ASD), and parental stress of ASD toddlers in China. Subjects in P-ESDM group (n = 23) were recruited from 1.5- to 2.5-year-old toddlers who were screened positive in Xuhui and Minhang Districts and were diagnosed with ASD. A community (comparison) group of age-matched toddlers with ASD (n = 20) was recruited from other areas...
February 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29407426/screening-language-skills-at-2-0
#14
Suvi-Maria Vehkavuori, Suvi Stolt
Early screening of children at risk for language difficulties is challenging. This study aimed to analyze the specificity and sensitivity of two screening methods at 2;0 years of age. In addition, the matter of what kind of information the use of word combinations and parental concern provide for screening was analyzed. The subjects were 78 children. The screening methods used were the Finnish versions of the short-form version of the MacArthur Communicative Development Inventories (FinCDI-SF) and the Communication and Symbolic Behavior Scales, Developmental Profile, Infant-Toddler Checklist (FinCSBS)...
January 18, 2018: Infant Behavior & Development
https://www.readbyqxmd.com/read/29399993/prediction-of-factor-viii-inhibitor-development-in-the-sippet-cohort-by-mutational-analysis-and-factor-viii-antigen-measurement
#15
S Spena, I Garagiola, A Cannavò, M Mortarino, P M Mannucci, F R Rosendaal, F Peyvandi
BACKGROUND: The type of F8 mutation is the main predictor of inhibitor development in patients with severe hemophilia A. Mutations expected to allow a residual synthesis of FVIII are likely to play a protective role towards alloantibody development by inducing immune tolerance. According to the expected full or partial impairment of FVIII synthesis, F8 variants are commonly classified as null and non-null. OBJECTIVES: To explore the mutation type-inhibitor risk association in a cohort of 231 patients with severe hemophilia A enrolled in the SIPPET (Survey of Inhibitors in Plasma-Product Exposed Toddlers) randomized trial...
February 5, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29399949/adaptive-behavior-in-infants-and-toddlers-with-down-syndrome-and-fragile-x-syndrome
#16
Elizabeth A Will, Kelly E Caravella, Laura J Hahn, Deborah J Fidler, Jane E Roberts
Individuals with Down syndrome (DS) experience deficits across all domains of adaptive functioning, however little is known about the emergence and age-related changes of these impairments compared to other neurogenetic disorders with similar intellectual disability impairments, such as fragile X syndrome (FXS). Adaptive behavior is key for optimal functioning in these populations. Participants aged 5-45 months comprised three age-matched groups, DS (n = 64), FXS (n = 69), and typically developing controls (TD; n = 69)...
February 5, 2018: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29398063/multiple-postnatal-infections-in-newborns-born-preterm-predict-delayed-maturation-of-motor-pathways-at-term-equivalent-age-with-poorer-motor-outcomes-at-3-years
#17
Torin J A Glass, Vann Chau, Ruth E Grunau, Anne Synnes, Ting Guo, Emma G Duerden, Justin Foong, Kenneth J Poskitt, Steven P Miller
OBJECTIVES: To evaluate whether the number of postnatal infections is associated with abnormal white matter maturation and poorer motor neurodevelopmental outcomes at 36 months of corrected age. STUDY DESIGN: A prospective longitudinal cohort study was undertaken of 219 newborns born preterm at 24-32 weeks of gestational age recruited between 2006 and 2013 with magnetic resonance imaging of the brain both early in life and at term-equivalent age. Postnatal infection was defined as any clinical infection or positive culture ≥72 hours after birth...
February 2, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29396720/cervicothoracic-epidural-hematoma-in-a-toddler-with-miosis-ptosis-nonspecific-symptoms-and-no-history-of-major-trauma-case-report
#18
Brandon K Root, Derrek A Schartz, Dan R Calnan, William F Hickey, David F Bauer
INTRODUCTION: Spinal epidural hematomas are uncommon in children. The diagnosis can be elusive as most cases present without a history of trauma, while symptoms can be atypical. CASE REPORT: We encountered a 35-month-old male presenting with nonspecific symptoms and no history of trauma. He later developed unilateral miosis and ptosis; MRI discovered a subacute cervicothoracic epidural which was promptly evacuated. The patient made an excellent recovery. COCLUSIONS: We emphasize the frequent absence of identifiable trauma and the importance of thorough imaging when this entity is suspected...
February 2, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29396705/biokinetics-dosimetry-and-radiation-risk-in-infants-after-99mtc-mag3-scans
#19
J Soares Machado, J Tran-Gia, S Schlögl, A K Buck, M Lassmann
BACKGROUND: Renal scans are among the most frequent exams performed on infants and toddlers. Due to the young age, this patient group can be classified as a high-risk group with a higher probability for developing stochastic radiation effects compared to adults. As there are only limited data on biokinetics and dosimetry in this patient group, the aim of this study was to reassess the dosimetry and the associated radiation risk for infants undergoing 99mTc-MAG3 renal scans based on a retrospective analysis of existing patient data...
February 2, 2018: EJNMMI Research
https://www.readbyqxmd.com/read/29392824/early-childhood-growth-and-cognitive-outcomes-findings-from-the-mal-ed-study
#20
Rebecca J Scharf, Elizabeth T Rogawski, Laura E Murray-Kolb, Angelina Maphula, Erling Svensen, Fahmida Tofail, Muneera Rasheed, Claudia Abreu, Angel Orbe Vasquez, Rita Shrestha, Laura Pendergast, Estomih Mduma, Beena Koshy, Mark R Conaway, James A Platts-Mills, Richard L Guerrant, Mark D DeBoer
Although many studies around the world hope to measure or improve developmental progress in children to promote community flourishing and productivity, growth is sometimes used as a surrogate because cognitive skills are more difficult to measure. Our objective was to assess how childhood measures of anthropometry correlate with measures of child development in low-income settings with high prevalence of poor nutrition and enteric disease, to inform studies considering growth outcomes in the absence of direct child developmental skill assessment...
February 2, 2018: Maternal & Child Nutrition
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