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Fabiën N Belle, Juliane Wenke-Zobler, Eva Cignacco, Ben D Spycher, Roland A Ammann, Claudia E Kuehni, Karin Zimmermann
BACKGROUND: Childhood cancer patients (CCP) have been reported to be at increased risk of becoming overweight during treatment. We assessed prevalence of overweight in CCP at diagnosis and at the end of treatment, determined risk factors, and identified weight change during treatment by type of cancer. METHODS: In a multicentre cohort study, we collected height and weight measurements of CCP at diagnosis and repeatedly during treatment. We calculated age- and sex-adjusted BMI Z-scores using references of the International Obesity Taskforce for children...
March 2, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
(no author information available yet)
OBJECTIVES: To ascertain the proportion of neonates and infants presenting with suspicion of an inborn error of metabolism in the centers identified by ICMR for newborn screening. METHODS: A set of red flag signs suggestive IEM were listed by the Taskforce members. The age group was limited to one year as it was understood that most of the small molecules with a severe phenotype would present before the age of one year. Further investigations were tandem mass spectrometry, gas chromatography mass spectrometry and high performance liquid chromatography...
March 15, 2018: Indian Journal of Pediatrics
I P M Jordans, R de Leeuw, S I Stegwee, N N Amso, P N Barri-Soldevila, T van den Bosch, T Bourne, H A M Brolmann, O Donnez, M Dueholm, W J K Hehenkamp, N Jastrow, D Jurkovic, R Mashiach, O Naji, I Streuli, D Timmerman, L F Vd Voet, J A F Huirne
OBJECTIVES: To generate a uniform, internationally recognized guideline for detailed uterine niche evaluation by ultrasonography in non-pregnant women using a modified Delphi method amongst international experts. METHODS: Fifteen international gynecological experts were recruited by their membership of the European niche taskforce group. All experts were physicians with extensive experience in niche evaluation in clinical practice and/or authors of niche studies...
March 14, 2018: Ultrasound in Obstetrics & Gynecology
Eric Crosbie, George Thomson, Becky Freeman, Stella Bialous
This study examines how health advocates and the Australian government responded to international commercial pressure during the implementation of tobacco standardised packaging (SP) as a measure to reduce non-communicable diseases (NCDs). Relevant government and NGO documents, and media items were reviewed. Policymakers and health advocates (n = 19) in Australia were interviewed. In 2009, Australia's National Health Taskforce recommended SP, which the Australian government announced in April 2010. In response, tobacco companies threatened the government with litigation in both domestic and international courts, claiming that SP would violate their investment and intellectual property rights...
February 27, 2018: Global Public Health
James Pickett, Cathy Bird, Clive Ballard, Sube Banerjee, Carol Brayne, Katherine Cowan, Linda Clare, Adelina Comas-Herrera, Lynne Corner, Stephanie Daley, Martin Knapp, Louise Lafortune, Gill Livingston, Jill Manthorpe, Natalie Marchant, Jo Moriarty, Louise Robinson, Clare van Lynden, Gill Windle, Bob Woods, Katherine Gray, Clare Walton
OBJECTIVE: National and global dementia plans have focused on the research ambition to develop a cure or disease-modifying therapy by 2025, with the initial focus on investment in drug discovery approaches. We set out to develop complementary research ambitions in the areas of prevention, diagnosis, intervention, and care and strategies for achieving them. METHODS: Alzheimer's Society facilitated a taskforce of leading UK clinicians and researchers in dementia, UK funders of dementia research, people with dementia, and carer representatives to develop, using iterative consensus methodology, goals and recommendations to advance dementia research...
February 22, 2018: International Journal of Geriatric Psychiatry
Rami Sommerstein, Barbara Hasse, Jonas Marschall, Hugo Sax, Michele Genoni, Matthias Schlegel, Andreas F Widmer
Investigations of a worldwide epidemic of invasive Mycobacterium chimaera associated with heater-cooler devices in cardiac surgery have been hampered by low clinical awareness and challenging diagnoses. Using data from Switzerland, we estimated the burden of invasive M. chimaera to be 156-282 cases/year in 10 major cardiac valve replacement market countries.
March 2018: Emerging Infectious Diseases
Melanie Calvert, Derek Kyte, Rebecca Mercieca-Bebber, Anita Slade, An-Wen Chan, Madeleine T King, Amanda Hunn, Andrew Bottomley, Antoine Regnault, An-Wen Chan, Carolyn Ells, Daniel O'Connor, Dennis Revicki, Donald Patrick, Doug Altman, Ethan Basch, Galina Velikova, Gary Price, Heather Draper, Jane Blazeby, Jane Scott, Joanna Coast, Josephine Norquist, Julia Brown, Kirstie Haywood, Laura Lee Johnson, Lisa Campbell, Lori Frank, Maria von Hildebrand, Michael Brundage, Michael Palmer, Paul Kluetz, Richard Stephens, Robert M Golub, Sandra Mitchell, Trish Groves
Importance: Patient-reported outcome (PRO) data from clinical trials can provide valuable evidence to inform shared decision making, labeling claims, clinical guidelines, and health policy; however, the PRO content of clinical trial protocols is often suboptimal. The SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) statement was published in 2013 and aims to improve the completeness of trial protocols by providing evidence-based recommendations for the minimum set of items to be addressed, but it does not provide PRO-specific guidance...
February 6, 2018: JAMA: the Journal of the American Medical Association
Brigitte Lamy, Agnès Ferroni, Claes Henning, Christian Cattoen, Patrice Laudat
BACKGROUND: Quality assurance and quality management are driving forces for controlling blood culture best practices but should not be disconnected from the end-point target, i.e., patient value. AIMS: This article is intended to help microbiologists implement blood culture accreditation that is actually beneficial to patient management. SOURCES: Experience from a nationwide taskforce for promoting quality assurance and competence in clinical microbiology laboratories, guidelines on blood culture...
February 1, 2018: Clinical Microbiology and Infection
Allan S Lichtman, William Parker, Barbara Goff, Neeraj Mehra, Eliane M Shore, Guylaine Lefebvre, Alexander Chiang, John Lenihan, Henk W R Schreuder
STUDY OBJECTIVE: To assess improvement of cognitive surgical knowledge of laparoscopic hysterectomy in post-graduate year (PGY) 1 and 2 gynecology residents who used an interactive computer-based Laparoscopic Hysterectomy Trainer. DESIGN: Multicenter prospective, randomized, controlled study (Canadian Taskforce Classification I). SETTING: Five Departments of Obstetrics and Gynecology: Keck School of Medicine of USC; University of California-Los Angeles; University of Washington; University of British Columbia; University of Toronto...
February 1, 2018: Journal of Minimally Invasive Gynecology
Dhrubodhi Mukherjee, Verletta Saxon
This exploratory paper presents a case study where a community based mental health organization forging a partnership with a local hospital system to establish a crisis stabilization unit (CSU) to address behavioral health emergency care. The study takes a mixed methods case study approach to address two research questions; (a) did this approach reduce the overall length of stay in the hospital emergency departments? (b) What challenges did the taskforce face in implementing this CSU model? The paper shares recommendation from the findings...
January 27, 2018: Community Mental Health Journal
Brigitte Decallonne, Emmanuel Bartholomé, Valérie Delvaux, Miguel D'haeseleer, Souraya El Sankari, Pierrette Seeldrayers, Bart Van Wijmeersch, Chantal Daumerie
This paper deals with thyroid disease that can occur after treatment with alemtuzumab (humanized monoclonal anti-CD52) for relapsing-remitting multiple sclerosis (MS). The 5-year incidence of thyroid adverse events in phase 3 clinical trials is up to 40.7%. In most cases, the thyroid dysfunction is mild and easily manageable and only few serious thyroid adverse events have been reported. The need for patient education on the risk of thyroid dysfunction, as well as regular clinical and biochemical thyroid function screening is well described...
January 25, 2018: Acta Neurologica Belgica
Wayne J English, Eric J DeMaria, Stacy A Brethauer, Samer G Mattar, Raul J Rosenthal, John M Morton
BACKGROUND: Bariatric surgery, despite being the most successful long-lasting treatment for morbid obesity, remains underused as only approximately 1% of all patients who qualify for surgery actually undergo surgery. To determine if patients in need are receiving appropriate therapy, the American Society for Metabolic and Bariatric Surgery created a Numbers Taskforce to specify annual rate of use for obesity treatment interventions. OBJECTIVES: The objective of this study was to determine metabolic and bariatric procedure trends since 2011 and to provide the best estimate of the number of procedures performed in the United States in 2016...
December 16, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Young-Kyun Lee, Hong Seok Kim, Hwan Seong Cho, Kyung-Hoi Koo
Atypical femoral fracture (AFF) has been widely issued since the American Society for Bone and Mineral Research (ASBMR) taskforce stated a possible association with long-term use of bisphosphonate in 2010. ASBMR taskforce recommended to include Paget's disease as one of variables to investigate the AFF in 2010. On the other hand, the ASBMR taskforce in 2014 excluded Paget's disease in the definition of AFF. Still, any rationale has been barely documented about this change. We described the rationale by reporting an 85-year-old man who had a subtrochanteric fracture with features of atypical femoral fracture which turned out to be Paget's disease of bone in the pathology...
September 2017: Clinical Cases in Mineral and Bone Metabolism
Magali Fassiotto, Caroline Simard, Christy Sandborg, Hannah Valantine, Jennifer Raymond
Faculty in academic medicine experience multiple demands on their time at work and at home, which can become a source of stress and dissatisfaction, compromising success. A taskforce convened to diagnose the state of work-life flexibility at Stanford University School of Medicine uncovered two major sources of conflict for faculty: work-life conflict, caused by juggling demands of career and home, and work-work conflict, caused by competing priorities of the tripartite research, teaching, and clinical mission of an academic medical center combined with service and administrative tasks...
January 2, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
A H Brand, P A DiSilvestro, J Sehouli, J S Berek
Surgery is the cornerstone of treatment of ovarian cancer. Given the importance of achieving no or minimal macroscopic residual disease at primary surgery, performing an assessment of the quality of ovarian cancer surgery is crucial. Assessing the quality of care and surgical outcome allows us to establish baseline information, set standards of care and clear priorities, enable benchmarking against peers, and sustain quality improvement. We know that suboptimal care exists and variation in outcomes results...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Carla White, Jeannine M Conway, Paula K Davis, Arcelia M Johnson-Fannin, Jeffrey G Jurkas, Nanci L Murphy, W Thomas Smith, Margarita Echeverri, Sharon L Youmans, Katie C Owings, Jennifer L Adams
The 2015-2017 American Association of Colleges of Pharmacy (AACP) Special Taskforce on Diversifying our Investment in Human Capital was appointed for a two-year term, due to the rigors and complexities of its charges. This report serves as a white paper for academic pharmacy on diversifying our investment in human capital. The Taskforce developed and recommended a representation statement that was adapted and adopted by the AACP House of Delegates at the 2016 AACP Annual Meeting. In addition, the Taskforce developed a diversity statement for the Association that was adopted by the AACP Board of Directors in 2017...
October 2017: American Journal of Pharmaceutical Education
Stanley K K Lam, Enid W Y Kwong, Maria S Y Hung, Samantha M C Pang, Vico C L Chiang
AIMS AND OBJECTIVES: To explore the core components that constitute nurses' preparedness in an epidemic event. BACKGROUND: Healthcare service providers have worked to augment efforts to protect the public from the impact of epidemic events. While constituting the major healthcare taskforce, nurses are frequently tasked with fronting the response to an infectious disease outbreak. Given the crucial role of nurses in the management of prevailing epidemics, the constituents of their preparedness in epidemic events should be identified...
November 29, 2017: Journal of Clinical Nursing
Pierre-Hugues Vivier, Thomas A Augdal, Fred E Avni, Justine Bacchetta, Rolf Beetz, Anna K Bjerre, Johan Blickman, Pierre Cochat, Rosana Coppo, Beatrice Damasio, Kassa Darge, Alaa El-Ghoneimi, Piet Hoebeke, Göran Läckgren, Marc-David Leclair, Maria-Luisa Lobo, Gianantonio Manzoni, Stephen D Marks, Girolamo Mattioli, Hans-Joachim Mentzel, Pierre Mouriquand, Tryggve Nevéus, Aikaterini Ntoulia, Lil-Sofie Ording-Muller, Josef Oswald, Frederica Papadopoulou, Gabriella Porcellini, Ekkehard Ring, Wolfgang Rösch, Ana F Teixeira, Michael Riccabona
To promote the standardization of nephro-uroradiological terms used in children, the European Society of Pediatric Radiology uroradiology taskforce wrote a detailed glossary. This work has been subsequently submitted to European experts in pediatric urology and nephrology for discussion and acceptance to improve the quality of radiological reports and communication among different clinicians involved in pediatric urology and nephrology.
December 2017: Journal of Pediatric Urology
J-P Liedtke, A Mandl, J Köther, J Chwieralski, K Shah-Hosseini, U Pieper-Fürst, S Allekotte, R Mösges
BACKGROUND: The Global Allergy and Asthma European Network (GA(2) LEN) Taskforce has requested more data on correlations between various Patient Reported Outcomes (PROs) in clinical trials on allergy. We compared three tools-the Rhinitis Control Assessment Test (RCAT), Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ), and Rhinitis Total Symptom Score (RTSS)-to determine whether the RCAT alone is a sufficient primary outcome parameter in clinical trials on allergic rhinoconjunctivitis...
November 21, 2017: Allergy
Joseph A Carcillo
No abstract text is available yet for this article.
December 2017: Critical Care Medicine
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