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https://www.readbyqxmd.com/read/28634314/-a-case-of-moyamoya-disease-associated-with-sapho-syndrome
#1
Nobutaka Horie, Mayuko Baba, Ken Kawada, Yuuki Matsunaga, Eisaku Sadakata, Yoichi Morofuji, Tsuyoshi Izumo, Minoru Morikawa, Takeo Anda, Takayuki Matsuo
Moyamoya disease is a unique occlusive disease of the internal carotid artery(ICA)with moyamoya vessels that can lead to transient ischemic attacks and hemorrhagic stroke. When other inherited or acquired disorders and conditions occur in conjunction with moyamoya disease, the syndrome is known as quasi-moyamoya disease. We report the case of a 34-year-old woman with a past history of SAPHO(Synovitis-Acne-Pustulosis-Hyperostosis-Osteomyelitis)syndrome, who presented with arm weakness and headache. Magnetic resonance angiography revealed severe terminal stenosis of the left ICA with moyamoya vessels, and she was diagnosed as moyamoya disease associated with SAPHO syndrome...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28629953/3d-black-blood-mr-angiography-of-the-carotid-arteries-a-simple-sequence-for-plaque-hemorrhage-and-stenosis-evaluation
#2
Monica Sigovan, Clément Bidet, Sébastien Bros, Loic Boussel, Laura Mechtouff, Philip M Robson, Zahi A Fayad, Antoine Millon, Philippe Douek
OBJECTIVES: To evaluate the diagnostic performance of a new three-dimensional T1-weighted turbo-spin-echo sequence (3D T1-w TSE) compared to 3D contrast-enhanced angiography (CE-MRA) for stenosis measurement and compared to 2D T1-w TSE for intra-plaque hemorrhage (IPH) detection. METHODS: Eighty three patients underwent carotid MRI, using a new elliptic-centric phase encoding T1-weighted 3D TSE sequence in addition to the clinical protocol. Two observers evaluated image quality, presence of flow artifacts, and presence of intra-plaque hemorrhage, and computed the NASCET degree of stenosis for CE-MRA and for the new sequence...
June 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28626049/dose-dependent-effect-of-statin-pretreatment-on-preventing-the-periprocedural-complications-of-carotid-artery-stenting
#3
Jeong-Ho Hong, Sung-Il Sohn, Jaehyuk Kwak, Joonsang Yoo, Hyuk Won Chang, O-Ki Kwon, Cheolkyu Jung, Inyoung Chung, Hee-Joon Bae, Ji Sung Lee, Moon-Ku Han
BACKGROUND AND PURPOSE: We investigated whether statin pretreatment can dose dependently reduce periprocedural complications in patients undergoing carotid artery stenting because of symptomatic carotid artery stenosis. METHODS: We enrolled a consecutive series of 397 symptomatic carotid artery stenosis (≥50% stenosis on conventional angiography) treated with carotid artery stenting at 2 tertiary university hospitals over a decade. Definition of periprocedural complications included any stroke, myocardial infarction, and death within 1 month after or during the procedure...
June 16, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28625670/carotid-occlusion-is-associated-with-more-frequent-neurovascular-events-than-moderately-severe-carotid-stenosis
#4
Matthew Janko, Ryan Moore, Ann H Kim, Andrew J Shevitz, Katherine L Morrow, David J Johnson, Vikram S Kashyap
OBJECTIVE: Asymptomatic internal carotid artery occlusion (CO) presents a clinical dilemma, and presently, the natural history, stroke risk, and optimal management remain ill defined. This study compared outcomes, including neurovascular events (NVEs) and health care costs, between patients with CO and patients with asymptomatic carotid artery stenosis (CS). METHODS: A prospectively maintained database was queried to identify patients with CO and CS with at least >50% carotid stenosis by duplex...
June 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28625130/remote-ischemic-conditioning-improves-cognitive-function-during-cerebral-vascular-injury-through-the-induction-of-autophagy
#5
Hongjuan Wang, Yang Xu, Hetao Bian, Cuiping Si, Zhongrui Yan, Meijia Zhu
BACKGROUND: The most valid model for vascular cognitive impairment (VCI) is the mouse bilateral common carotid artery stenosis (BCAS), whose behavioral outcomes is supposedly affected by the remote ischemic conditioning (RIC) through the induction of autophgy. We hope to determine whether RIC contributes to the neuroprotection through the induction of autophagy.. METHODS: Wastar male mice were randomized into three groups including the Sham, the BCAS and the RIC+BCAS groups...
June 18, 2017: Current Neurovascular Research
https://www.readbyqxmd.com/read/28623743/repeated-measurements-of-serum-concentrations-of-tnf-alpha-interleukin-6-and-interleukin-10-in-the-evaluation-of-internal-carotid-artery-stenosis-progression
#6
Przemyslaw Puz, Anetta Lasek-Bal
BACKGROUND AND AIMS: The inflammatory process (with TNFα, interleukin-6 and interleukin-10 involvement) plays a key role in the development, progression and destabilization of atherosclerotic plaques. The aim of this study was to assess the importance of double-checked measurements of TNFα, interleukin-6 (IL-6) and interleukin-10 (Il-10) serum levels in patients with internal carotid artery (ICA) stenosis to determine the dynamics of changes in the stenosis degree and in the ultrasound plaque morphology...
June 3, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28623378/carotid-stenting-in-neuroradiology-a%C3%A2-short-journey-from-the-past-to-current-debates
#7
REVIEW
Joachim Berkefeld, Marlies Wagner, Richard du Mesnil
After a period of stagnation due to negative results of randomized trials for patients with symptomatic stenosis, the relevance of carotid artery stenting (CAS) is increasing again. CAS has become an important and evidence-based part of interventional stroke treatment. Our ability to manage acute recanalization of carotid occlusions and other niche indications properly led some skeptical neurologists to trust in carotid intervention for elective cases as well. The evolution of CAS from initial euphoria to more realistic views under consideration of trial results and guidelines is reviewed...
June 16, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28623117/open-heart-surgery-does-not-increase-the-incidence-of-ipsilateral-ischemic-stroke-in-patients-with-asymptomatic-severe-carotid-stenosis
#8
John E Castaldo, Hussam A Yacoub, Yuebing Li, Hope Kincaid, Donna Jenny
BACKGROUND AND PURPOSE: We evaluated the incidence of perioperative stroke following the institution's 2007 practice change of discontinuing combined carotid endarterectomy and open heart surgery (OHS) for patients with severe carotid stenosis. METHODS: In this retrospective cohort study, we compared 113 patients undergoing coronary artery bypass grafting, aortic valve replacement, or both from 2007 to 2011 with data collected from 2001 to 2006 from a similar group of patients...
June 13, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28620501/efficacy-of-lenvatinib-in-a-patient-with-anaplastic-thyroid-cancer
#9
Kazuyuki Oishi, Daisuke Takabatake, Yuichi Shibuya
We experienced a case of an 82-year-old woman who presented to our hospital with a 1-month history of dysphagia and dyspnea. Cervical contrast-enhanced computed tomography revealed diffuse thyroid neoplasms causing significant tracheal stenosis with tumors, particularly of the superior mediastinum, which were associated with an embolism of the brachiocephalic vein and suspected invasion to the bilateral common carotid arteries. Anaplastic thyroid cancer (ATC) was diagnosed by fine-needle aspiration; thus, emergency tracheostomy and gastrostomy were performed...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28617845/frequency-and-significance-of-rare-rnf213-variants-in-patients-with-adult-moyamoya-disease
#10
Mi-Ae Jang, Jong-Won Chung, Je Young Yeon, Jong-Soo Kim, Seung Chyul Hong, Oh Young Bang, Chang-Seok Ki
PURPOSE: Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by stenosis of the internal carotid arteries with compensatory development of collateral vessels. Although a founder variant of RNF213, p.Arg4810Lys (c.14429G>A, rs112735431), is a major genetic risk factor for MMD in East Asians, the frequency and disease susceptibility of other variants in this gene remain largely unknown. In the present study, we investigated the association of RNF213 variants with MMD in Korean patients and population controls...
2017: PloS One
https://www.readbyqxmd.com/read/28614214/a-rare-case-of-multiple-thrombi-in-a-giant-left-atrium
#11
Alfredo Intorcia, Marco A Perrone, Riccardo Morgagni, Domenico Sergi, Massimo Marchei, Mauro Borzi, Francesco Romeo
: Giant left atrium is frequently associated with rheumatic mitral valve disease. The incidence of left atrial thrombus among patients with mitral stenosis and atrial fibrillation varies from 7 to 38%. Anticoagulation therapy achieves a high rate of resolution of left atrial appendage (LAA) and left atrial cavity thrombi, but in selected patients surgical therapy must be considered. An 81-year-old woman presented to our emergency department with repeated episodes of transient ischemic attack. She had a history of carotid artery stenosis, chronic lymphocytic leukemia, rheumatic heart disease, and paroxysmal atrial fibrillation...
June 12, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28611836/simultaneous-kissing-stenting-a-valuable-technique-for-reconstructing-the-stenotic-initial-segment-of-the-right-subclavian-artery
#12
Ping Zhang, Daiqi Chen, Daishi Tian, Qiang Zhang, Minghuan Wang, Qian Li, Xiang Luo
Atherosclerotic stenosis or occlusion often involves the subclavian artery. For lesions that are close to the orifice of the right subclavian artery, stenting of the right subclavian artery itself blocks the pathway from the innominate artery to the right carotid artery and causes problems in patients with multiple angiostenosis, especially involving the right carotid system. In this study, we report 2 cases using simultaneous kissing stenting (SKS) of the right subclavian artery and the right carotid artery to relieve right subclavian stenosis and maintain right carotid system patency...
March 2017: Interventional Neurology
https://www.readbyqxmd.com/read/28611828/heads-up-a-novel-provocative-maneuver-to-guide-acute-ischemic-stroke-management
#13
Latisha K Ali, Julius K Weng, Sidney Starkman, Jeffrey L Saver, Doojin Kim, Bruce Ovbiagele, Brian H Buck, Nerses Sanossian, Paul Vespa, Oh Young Bang, Reza Jahan, Gary R Duckwiler, Fernando Viñuela, David S Liebeskind
BACKGROUND: A common dilemma in acute ischemic stroke management is whether to pursue recanalization therapy in patients with large vessel occlusions but minimal neurologic deficits. We describe and report preliminary experience with a provocative maneuver, i.e. 90-degree elevation of the head of bed for 30 min, which stresses collaterals and facilitates decision-making. METHODS: A prospective cohort study of <7.5 h of acute anterior circulation territory ischemia patients with minimal deficits despite middle cerebral artery (MCA) or internal carotid artery (ICA) occlusive disease...
March 2017: Interventional Neurology
https://www.readbyqxmd.com/read/28611148/failure-to-account-for-practice-effects-leads-to-clinical-misinterpretation-of-cognitive-outcome-following-carotid-endarterectomy
#14
Christopher J Marley, Andrew Sinnott, Judith E Hall, Gareth Morris-Stiff, Paul V Woodsford, Michael H Lewis, Damian M Bailey
Carotid endarterectomy (CEA) is a surgical procedure to remove stenotic atherosclerotic plaque from the origin of the carotid artery to reduce the risk of major stroke. Its impact on postoperative cognitive function (POCF) remains controversial; complicated, in part, by a traditional failure to account for practice effects incurred during consecutive psychometric testing. To address this for the first time, we performed psychometric testing (learning and memory, working memory, attention and information processing, and visuomotor coordination) in 15 male patients aged 68 ± 8 years with symptomatic carotid stenosis the day before and 24 h following elective CEA (two consecutive tests, 48 h apart)...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28606007/dimethyl-fumarate-improves-white-matter-function-following-severe-hypoperfusion-involvement-of-microglia-macrophages-and-inflammatory-mediators
#15
Jill H Fowler, Jamie McQueen, Philip R Holland, Yasmina Manso, Martina Marangoni, Fiona Scott, Emma Chisholm, Robert H Scannevin, Giles E Hardingham, Karen Horsburgh
The brain's white matter is highly vulnerable to reductions in cerebral blood flow via mechanisms that may involve elevated microgliosis and pro-inflammatory pathways. In the present study, the effects of severe cerebral hypoperfusion were investigated on white matter function and inflammation. Male C57Bl/6J mice underwent bilateral common carotid artery stenosis and white matter function was assessed at seven days with electrophysiology in response to evoked compound action potentials (CAPs) in the corpus callosum...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28605922/surgical-coronary-revascularization-on-pump-versus-off-pump-in-patients-with-stenosis-of-the-main-tree-of-the-left-coronary-artery-and-carotid-stenosis
#16
Edin Kabil, Bedrudin Banjanović, Emir Mujanović
OBJECTIVE: The aim of this study was to show perioperative complications of CABG procedure with and without cardiopulmonary bypass (CPB) in patients with combined coronary and carotid disease. PATIENTS AND METHODS: This retrospective survey included patients with left main stenosis greater than 50% and carotid stenosis over 50%, who had undergone CABG without carotid endarterectomy at the BH Heart Centre, from May 2009 to May 2014. The patients were divided into two groups according to the surgical method used...
May 2017: Acta Medica Academica
https://www.readbyqxmd.com/read/28604285/hybrid-treatment-of-extracranial-carotid-artery-disease
#17
Joseph Bozzay, Mike Broce, Albeir Y Mousa
OBJECTIVE: High-degree stenosis of both innominate (IA) or left common carotid artery (CCA) and carotid bifurcation is uncommon but still represents a significant challenge to interventionists in many aspects including techniques, timing, and priority. There are several strategies for intervention that have been reported in the literature. A well-described, less-invasive strategy for extracranial tandem carotid lesions is concomitant carotid endarterectomy (CEA) with retrograde carotid angioplasty and stenting (CAS)...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28603515/factors-influencing-decision-making-for-carotid-endarterectomy-versus-stenting-in-the-very-elderly
#18
REVIEW
Sung Hyuk Heo, Cheryl D Bushnell
As the population ages worldwide, the number of elderly patients with carotid stenosis is also increasing. There have been many large clinical trials comparing carotid endarterectomy (CAE) versus stenting, but the inclusion criteria (i.e., symptomatic or asymptomatic), stenting methods (i.e., protection device), and primary end point (i.e., the definition of myocardial infarction and follow-up period) were different between trials. Therefore, the interpretation of those results is difficult and requires attention...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28599905/potential-of-new-generation-double-layer-micromesh-stent-for-carotid-artery-stenting-in-patients-with-unstable-plaque-%C3%A2-a-preliminary-result-using-ofdi-analysis-%C3%A2
#19
Kiyofumi Yamada, Shinichi Yoshimura, Masatomo Miura, Takuya Kanamaru, Seigo Shindo, Kazutaka Uchida, Manabu Shirakawa, Masahiko Shibuya, Takahiro Imanaka, Masaharu Ishihara, Tohru Masuyama, Reiichi Ishikura, Masanori Kawasaki
BACKGROUND: One of the disadvantages of carotid artery stenting (CAS) is high incidence of distal embolism (DE) during or after the procedure. It has been reported that unstable plaque cases are at high risk of DE and plaque protrusion (PP) after stent placement which will become a cause of post procedural ischemic complications. OBJECTIVE: The purpose of this study was to compare the rate and size of PP between CASPER stent which is a new generation double-layer micromesh stent and conventional stents detected by optical frequency domain imaging (OFDI) and to evaluate the efficacy of CAS with CASPER stent for cases with unstable plaque...
June 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28599682/bilateral-ocular-ischemia-induced-blindness-as-a-presenting-manifestation-of-takayasu-arteritis-a-case-report
#20
Pedro Pallangyo, Emmanuel Epafra, Paulina Nicholaus, Frederick Lyimo, Parvina Kazahura, Mohamed Janabi
BACKGROUND: Takayasu arteritis is a granulomatous panarteritis that predominantly affects the aorta and its major branches. The initial manifestations of this large-vessel vasculitis are usually nonspecific; however, as the disease progresses, typical symptoms of arterial occlusion, aneurysmal formation, and vascular pain become evident. Ischemic ocular complications of Takayasu arteritis which could lead to complete loss of vision are not uncommon and depend on the obliterated portion(s) of carotid(s), the intensity and rate of progression of ocular vascular insufficiency, and sufficiency of the collateral blood supply to the eye...
June 10, 2017: Journal of Medical Case Reports
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