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Plastic bronchitis

Norbert Garcia-Henriquez, Eric M Toloza, Farah Khalil, Maria F Echavarria, Joseph R Garrett, Carla C Moodie, Frank J Kaszuba, Jacques P Fontaine
We present the case of a 55-year-old man who developed extensive occlusive bronchial casts after trachea-esophageal (TE) fistula repair. The bronchial casts were treated by bronchoscopic extraction, high dose steroids, antibiotics, and antifungals. Despite this multi-modality treatment, the rapid formation of these occlusive bronchial casts was very aggressive and could not be controlled even with a series of five rigid bronchoscopic extractions within a 48-hour period. The patient quickly deteriorated and succumbed to the inflammatory state...
September 2016: Journal of Thoracic Disease
Gregory P Downey, Yael Aschner
No abstract text is available yet for this article.
October 2016: Annals of the American Thoracic Society
Anil K Singhi, Sivakumar Kothandum
Failing Fontan physiology in univentricular hearts manifest with protein-losing enteropathy, plastic bronchitis, low cardiac output, and recurrent effusions. Transcatheter creation of fenestration in a failing Fontan may be useful in alleviating the symptoms by improving the cardiac output. It is traditionally achieved by puncturing through the conduit from femoral or jugular venous access. In the absence of good venous path, transhepatic access provides a direct route for needle puncture of the conduit. If marked intimal ingrowth into the conduit results in increasing rigidity and makes the conduit nonyielding, alternative approaches may be needed...
September 2016: Annals of Pediatric Cardiology
Maxim G Itkin, Francis X McCormack, Yoav Dori
RATIONALE: Plastic bronchitis is a condition characterized by expectoration of branching bronchial casts. Although the mechanism of cast formation in adults with plastic bronchitis remains poorly understood, abnormal pulmonary lymphatic flow resulting in molding of congealing lymphatic fluids in the airway has been documented as a cause of the disease in children with congenital heart disease. OBJECTIVES: To use advanced lymphatic imaging techniques, including dynamic contrast-enhanced magnetic resonance (MR) lymphangiography (DCMRL) and intranodal lymphangiography, to investigate the mechanism of cast formation in adult patients with plastic bronchitis, and to evaluate the therapeutic outcome of percutaneous lymphatic embolization for these patients...
October 2016: Annals of the American Thoracic Society
Carlos J Guevara, Kristy L Rialon, Raja S Ramaswamy, Seung K Kim, Michael D Darcy
PURPOSE: To describe technical details, success rate, and advantages of direct puncture of the thoracic duct (TD) under direct ultrasound (US) guidance at venous insertion in the left neck. MATERIALS AND METHODS: All patients who underwent attempted thoracic duct embolization (TDE) via US-guided retrograde TD access in the left neck were retrospectively reviewed. Indications for lymphangiography were iatrogenic chyle leak, pulmonary lymphangiectasia, and plastic bronchitis...
August 29, 2016: Journal of Vascular and Interventional Radiology: JVIR
Bruce K Rubin
Plastic bronchitis is an uncommon and probably underrecognized disorder, diagnosed by the expectoration or bronchoscopic removal of firm, cohesive, branching casts. It should not be confused with purulent mucous plugging of the airway as seen in patients with cystic fibrosis or bronchiectasis. Few medications have been shown to be effective and some are now recognized as potentially harmful. Current research directions in plastic bronchitis research include understanding the genetics of lymphatic development and maldevelopment, determining how abnormal lymphatic malformations contribute to cast formation, and developing new treatments...
September 2016: Clinics in Chest Medicine
Tanmay S Panchabhai, Sanjay Mukhopadhyay, Sameep Sehgal, Debabrata Bandyopadhyay, Serpil C Erzurum, Atul C Mehta
Although mucus is a normal product of the tracheobronchial tree, some diseases of the respiratory tract are characterized by unusually thick (inspissated) forms of mucus that accumulate within the airways. These are known as mucus plugs. The pathologic composition of these plugs is surprisingly diverse and, in many cases, correlates with distinctive clinical, radiologic, and bronchoscopic findings. The best-known conditions that involve mucus plugs are allergic bronchopulmonary aspergillosis, plastic bronchitis, and asthma...
July 18, 2016: Chest
Yoav Dori, Maxim Itkin
No abstract text is available yet for this article.
August 2016: Journal of Thoracic and Cardiovascular Surgery
Matthew P Kirschen, Yoav Dori, Maxim Itkin, Daniel J Licht, Rebecca Ichord, Arastoo Vossough
An adolescent with plastic bronchitis due to congenital heart disease had altered mental status after an interventional lymphatic procedure in which lipiodol contrast was used. Neuroimaging revealed cerebral lipiodol embolization due to direct shunting between lymphatic channels and pulmonary veins. Cerebral lipiodol embolization is a potential neurologic morbidity associated with interventional lymphatic procedures.
September 2016: Journal of Pediatrics
Helena J Maier, Benjamin W Neuman, Erica Bickerton, Sarah M Keep, Hasan Alrashedi, Ross Hall, Paul Britton
Positive-strand RNA (+RNA) viruses rearrange cellular membranes during replication, possibly in order to concentrate and arrange viral replication machinery for efficient viral RNA synthesis. Our previous work showed that in addition to the conserved coronavirus double membrane vesicles (DMVs), Beau-R, an apathogenic strain of avian Gammacoronavirus infectious bronchitis virus (IBV), induces regions of ER that are zippered together and tethered open-necked double membrane spherules that resemble replication organelles induced by other +RNA viruses...
2016: Scientific Reports
Pradeepkumar Charlagorla, John P Breinholt
Plastic bronchitis is a rare life-threatening complication of the Fontan operation. Transcatheter Fontan fenestration can ameliorate symptoms by decompressing elevated venous pressures. Transcatheter creation of a fenestration can be technically challenging in cases with complex venous anatomy. We report a case of a 5-year-old boy with heterotaxy, dextrocardia with unbalanced atrioventricular canal (AVC), atrial and visceral situs inversus, left-sided superior vena cava (SVC), and left-sided interrupted inferior vena cava (IVC) with azygos continuation...
May 2016: Annals of Pediatric Cardiology
Anna Wesnerowicz, Pawel Nawrocki, Kerstin Wagner, Edward Malec, Katarzyna Januszewska
No abstract text is available yet for this article.
2016: Kardiologia Polska
Shinya Ugaki, David J E Lord, Megan C Sherwood, David S Winlaw
No abstract text is available yet for this article.
August 2016: Journal of Thoracic and Cardiovascular Surgery
Tutku Soyer, Şule Yalcin, Nagehan Emiralioğlu, Ebru Arik Yilmaz, Ozge Soyer, Diclehan Orhan, Deniz Doğru, Bülent Enis Sekerel, Feridun Cahit Tanyel
AIM: Plastic bronchitis (PB) is a rare disorder characterized by formation of bronchial casts (BC) in the tracheobronchial tree with partial or complete airway obstruction. Although lysis of casts with several fibrinolytic agents has been reported, removal of BC with bronchoscope provides better clearance of airways. A retrospective study was performed to evaluate the use of serial rigid bronchoscopy (RB) in the treatment of PB in children. PATIENTS AND METHODS: Between 2011 and 2015, children with partial or complete airway obstruction with PB were evaluated for age, gender, underlying disease, clinical findings, results of bronchoscopic interventions and histopathologic findings...
October 2016: Journal of Pediatric Surgery
Patricia Demont, Tobias Fehr, Thomas Geiser, Sebastian R Ott
No abstract text is available yet for this article.
2016: Respiration; International Review of Thoracic Diseases
Monali H Patil, Attiya Siddiqi, M Jeffrey Mador
Plastic bronchitis is a rare disorder, characterized by formation of thick fibrinous bronchial casts which can obstruct the airway and present as a life threatening emergency (1). It is more common in the pediatric population after corrective or palliative surgery for congenital heart disease like fontan procedure but has rarely been reported in adults as well (1). Pregnancy is a relative contraindication for bronchoscopy. Bronchoscopy in the pregnant patient poses significant risks as manipulation of the airway can lead to impaired oxygenation and ventilation...
2016: Respiratory Medicine Case Reports
Masamichi Ono, Jelena Kasnar-Samprec, Alfred Hager, Julie Cleuziou, Melchior Burri, Constantin Langenbach, Alessia Callegari, Martina Strbad, Manfred Vogt, Jürgen Hörer, Christian Schreiber, Rüdiger Lange
OBJECTIVES: This study aims to evaluate the clinical outcome following total cavopulmonary connection (TCPC) and to identify factors affecting early and late outcome. METHODS: Between May 1994 and March 2015, 434 patients underwent TCPC with 50 lateral tunnels and 374 extracardiac conduits. The clinical outcome, exercise capacity and liver examination results were retrospectively reviewed. RESULTS: Thirty-day survival was 98.2%, and the estimated survival rate at 15 years was 92...
March 23, 2016: European Journal of Cardio-thoracic Surgery
Rita Padoan, Piercarlo Poli, Domenico Colombrita, Elisa Borghi, Silviana Timpano, Marco Berlucchi
Fungi are known pathogens in cystic fibrosis patients. A boy with cystic fibrosis boy presented with acute respiratory distress. Bronchoscopy showed airways obstruction by mucus plugs and bronchial casts. Scedosporium apiospermum was identified as the only pathogen. Bronchoalveolar lavage successfully resolved the acute obstruction. Plastic bronchitis is a new clinical picture of acute Scedosporium endobronchial colonization in cystic fibrosis patients.
June 2016: Pediatric Infectious Disease Journal
Ahmad Y Sheikh, Mastaneh Ahmadi-Kashani, Vibha Mohindra, Allison Friedenberg, Sharmila B Pramanik, William D Ogden
Plastic bronchitis is a rare life-threatening complication observed after cardiopulmonary bypass (CPB). We describe a case of a 54-year-old man in whom a fulminant case of plastic bronchitis developed after coronary artery bypass grafting (CABG) and mitral valve repair. A brief review of the literature is also presented.
March 2016: Annals of Thoracic Surgery
Yafang Wang, Yingluan Song, Xiaodong Wang, Lili Zhang, Xiaofeng Liu, Xin Wen, Haitao Zhao
OBJECTIVE: To explore the role of rigid bronchoscope in the diagnosis and treatment of plastic bronchitis. METHODS: Various clinical parameters, the key points of operation and postoperative recovery were analyzed in 8 patients with plastic bronchitis treated in Department and ICU using retrospective analysis. RESULTS: All cases demonstrated bronchial lumen stenosis, mucous membrance coarse, congestion, edema in the affected side. 2 cases had follicular hyperplasia, 1 case had a few ooze after taking out the plastic type...
November 2015: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
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