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Blood pressure, pulse pressure, end organ damage

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https://www.readbyqxmd.com/read/29691159/a-cross-sectional-study-of-the-prevalence-of-exercise-induced-hypertension-in-childhood-following-repair-of-coarctation-of-the-aorta
#1
Taryn L Luitingh, Melissa G Y Lee, Bryn Jones, Remi Kowalski, Sofia Weskamp Aguero, Jane Koleff, Diana Zannino, Michael M H Cheung, Yves d'Udekem
BACKGROUND: Exercise-testing may be a more tolerable method of detecting hypertension in children after coarctation repair compared to gold-standard 24-hour ambulatory blood pressure (BP) monitoring (ABPM). This study aims to determine the prevalence of exercise-induced hypertension and end-organ damage in children after coarctation repair, and the effectiveness of exercise-testing compared to 24-hour ABPM in this population. METHODS: Exercise-testing (Bruce protocol), transthoracic echocardiogram, 24-hour ABPM, and pulse wave velocity were performed in 41 patients aged 8 to 18 years with previous coarctation repair...
March 27, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29465711/relation-of-blood-pressure-and-organ-damage-comparison-between-feasible-noninvasive-central-hemodynamic-measures-and-conventional-brachial-measures
#2
Annika S Lindroos, Ville L Langén, Ilkka Kantola, Veikko Salomaa, Eeva P Juhanoja, Sam S Sivén, Pekka Jousilahti, Antti M Jula, Teemu J Niiranen
OBJECTIVE: The present cross-sectional study investigated whether central SBP and pulse pressure (PP) measured noninvasively with a novel cuff-based stand-alone monitor are more strongly associated with hypertensive end-organ damage than corresponding brachial measures. METHODS: We investigated the cross-sectional association of central versus brachial SBP and PP with echocardiographic left ventricular mass index (LVMI), LV hypertrophy (LVH), carotid intima-media thickness (IMT), and increased IMT (IMT ≥ 75th percentile) among 246 participants drawn from the general population (mean age 57...
June 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29180796/sexual-dysfunction-as-a-determinant-of-cardiovascular-outcome-in-patients-undergoing-chronic-hemodialysis
#3
Vedran Premužić, Bojan Jelaković
Sexual dysfunction (SD) is common in men and women with chronic kidney disease (CKD) and is considered as an early marker for cardiovascular (CV) disease. We hypothesized that patients with SD have higher risk for vascular damage of the large arteries, accelerated vascular aging, and consequently higher CV mortality than other end-stage renal disease (ESRD) patients. In this study, the International Index of Erectile Function (IIEF) questionnaire and the Female Sexual Function Index (FSFI) questionnaire were applied in men and women, respectively...
November 27, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28926375/early-effects-of-renal-replacement-therapy-on-cardiovascular-comorbidity-in-children-with-end-stage-kidney-disease-findings-from-the-4c-t-study
#4
Bernhard M W Schmidt, Rizky Indrameikha Sugianto, Daniela Thurn, Karolis Azukaitis, Aysun K Bayazit, Nur Canpolat, Ayse Guler Eroglu, Salim Caliskan, Anke Doyon, Ali Duzova, Tevfik Karagoz, Ali Anarat, Murat Deveci, Sevgi Mir, Bruno Ranchin, Rukshana Shroff, Esra Baskin, Mieczyslaw Litwin, Z Birsin Özcakar, Rainer Büscher, Oguz Soylemezoglu, Jiri Dusek, Markus J Kemper, Maria C Matteucci, Sandra Habbig, Guido Laube, Elke Wühl, Uwe Querfeld, Anja Sander, Franz Schaefer, Anette Melk
BACKGROUND: The early impact of renal transplantation on subclinical cardiovascular measures in pediatric patients has not been widely investigated. This analysis is performed for pediatric patients participating in the prospective cardiovascular comorbidity in children with chronic kidney disease study and focuses on the early effects of renal replacement therapy (RRT) modality on cardiovascular comorbidity in patients receiving a preemptive transplant or started on dialysis. METHODS: We compared measures indicating subclinical cardiovascular organ damage (aortal pulse wave velocity, carotid intima media thickness, left ventricular mass index) and evaluated cardiovascular risk factors in 166 pediatric patients before and 6 to 18 months after start of RRT (n = 76 transplantation, n = 90 dialysis)...
March 2018: Transplantation
https://www.readbyqxmd.com/read/28575172/longitudinal-changes-in-excess-pressure-independently-predict-declining-renal-function-among-healthy-individuals-a-pilot-study
#5
Rachel E D Climie, Dean S Picone, James E Sharman
BACKGROUND: Aortic reservoir function independently predicts end-organ damage in cross-sectional analyses. However, longitudinal associations are more important regarding causation, but this has never been examined at rest or in response to light-moderate intensity exercise. The aim of this study was to determine the association between the change in aortic reservoir characteristics, in particular excess pressure integral (Pexcess) at rest and in response to exercise and the change in kidney function among healthy individuals followed over time...
August 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/27900498/central-hemodynamics-and-arterial-stiffness-in-idiopathic-and-multiple-system-atrophy
#6
COMPARATIVE STUDY
Klaas Franzen, Sabine Fliegen, Jelena Koester, Rafael Campos Martin, Günther Deuschl, Michael Reppel, Kai Mortensen, Susanne A Schneider
Blood pressure is commonly abnormal in parkinsonian disorders, but central hemodynamics and arterial stiffness, well-established predictors of total cardiovascular risk, have rarely been studied in these disorders. 32 patients [27 with idiopathic Parkinson's disease (iPD); 5 with multiple system atrophy (MSA)] and 15 controls matched for cardiac risk factors underwent 24 h-ambulatory blood pressure recordings using an I.E.M. device (Mobil-O-Graph™), measuring peripheral pressure and calculating central pressures and arterial stiffness...
February 2017: Journal of Neurology
https://www.readbyqxmd.com/read/27815929/challenges-in-the-management-of-hypertension-in-older-populations
#7
REVIEW
Lisa Pont, Tariq Alhawassi
The prevalence of hypertension increases with age making it a significant health concern for older persons. Aging involves a range of physiological changes such as increases in arterial stiffness, widening pulse pressure, changes in renin and aldosterone levels, decreases in renal salt excretion, declining in renal function, changes in the autonomic nervous system sensitivity and function and changes to endothelial function all of which may not only affect blood pressure but may also affect individual response to pharmacotherapy used to manage hypertension and prevent end organ damage and other complications associated with poor blood pressure control...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27754006/js-ish-esh-2-update-on-the-detection-and-follow-up-of-early-hypertensive-heart-disease
#8
Enrico Agabiti Rosei
Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753950/os-07-06-the-association-between-home-versus-ambulatory-nighttime-blood-pressure-and-end-organ-damage-in-the-general-population
#9
Annika Lindroos, Jouni Johansson, Pauli Puukka, Ilkka Kantola, Veikko Salomaa, Eeva Juhanoja, Sam Sivén, Pekka Jousilahti, Antti Jula, Teemu Niiranen
OBJECTIVE: The aim of this study was to test the agreement between nighttime home and nighttime ambulatory blood pressure (BP) and to compare their associations with hypertensive end-organ damage for the first time in the general population. DESIGN AND METHOD: A population sample of 248 participants underwent measurements for nighttime home BP (3 measurements on 2 nights with a timer-equipped home device), nighttime ambulatory BP, pulse wave velocity (PWV), carotid intima-media thickness (IMT) and echocardiographic left ventricular mass index (LVMI)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753855/hw-01-3-cardiac-and-vascular-mri-in-hypertension-evaluation
#10
Sang-Chol Lee
Chronic hypertension can result in deleterious effects on various vascular organs including the heart and vessels. Cardiovascular magnetic resonance (CMR) has the unique advantage of the ability to assess ventricular volumes and function, valvular abnormalities, vascular pathology, myocardial perfusion and tissue characterization with high accuracy and reproducibility and also avoid the risk of radiation. As this is the case, CMR seems to be an ideal method for comprehensive assessment of patients with systemic hypertension...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27651468/albuminuria-and-masked-uncontrolled-hypertension-in-chronic-kidney-disease
#11
Rajiv Agarwal
Background: Masked uncontrolled hypertension (MUCH) is associated with greater target organ damage such as left ventricular hypertrophy, increased arterial stiffness and albuminuria. Whether MUCH independently associates with greater cardiovascular end-organ damage or kidney damage is unclear. The objective of this study was to assess the strength of the relationship of MUCH (awake ambulatory blood pressure ≥135/85 mmHg and clinic blood pressure <140/90 mmHg) with target organ damage...
December 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27643345/os-07-06-the-association-between-home-versus-ambulatory-nighttime-blood-pressure-and-end-organ-damage-in-the-general-population
#12
Annika Lindroos, Jouni Johansson, Pauli Puukka, Ilkka Kantola, Veikko Salomaa, Eeva Juhanoja, Sam Sivén, Pekka Jousilahti, Antti Jula, Teemu Niiranen
OBJECTIVE: The aim of this study was to test the agreement between nighttime home and nighttime ambulatory blood pressure (BP) and to compare their associations with hypertensive end-organ damage for the first time in the general population. DESIGN AND METHOD: A population sample of 248 participants underwent measurements for nighttime home BP (3 measurements on 2 nights with a timer-equipped home device), nighttime ambulatory BP, pulse wave velocity (PWV), carotid intima-media thickness (IMT) and echocardiographic left ventricular mass index (LVMI)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643092/hw-01-3-cardiac-and-vascular-mri-in-hypertension-evaluation
#13
Sang-Chol Lee
Chronic hypertension can result in deleterious effects on various vascular organs including the heart and vessels. Cardiovascular magnetic resonance (CMR) has the unique advantage of the ability to assess ventricular volumes and function, valvular abnormalities, vascular pathology, myocardial perfusion and tissue characterization with high accuracy and reproducibility and also avoid the risk of radiation. As this is the case, CMR seems to be an ideal method for comprehensive assessment of patients with systemic hypertension...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642917/js-ish-esh-2-update-on-the-detection-and-follow-up-of-early-hypertensive-heart-disease
#14
Enrico Agabiti Rosei
Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27579902/ambulatory-versus-clinic-blood-pressure-in-predicting-overall-subclinical-target-organ-damage-progression-in-essential-hypertensive-patients-a-3-year-follow-up-study
#15
Yan Yang, Jian-Zhong Xu, Yan Wang, Ping-Jin Gao
BACKGROUND: Ambulatory blood pressure (BP) was shown to predict specific subclinical target organ damage (TOD) progression better than clinic BP, whereas the usefulness of ambulatory and clinic BP measurements to predict overall TOD progression is not well established. METHODS AND RESULTS: Clinic and 24-h ambulatory BP values were obtained in 280 patients on baseline. A total of 199 participants (mean age 62.5±9.5, 59.3% men) were followed up for an average of 39 months and overall subclinical TOD were recorded at the end of follow-up period...
December 2016: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27508780/-op-6b-07-nighttime-blood-pressure-measured-with-a-timer-equipped-home-device-an-alternative-to-ambulatory-monitoring
#16
A Lindroos, A Jula, P Puukka, I Kantola, V Salomaa, E Juhanoja, S Sivén, P Jousilahti, J Johansson, T Niiranen
OBJECTIVE: Our objective was to test the agreement between nighttime home and nighttime ambulatory blood pressure (BP) and to compare their associations with left ventricular hypertrophy, arterial stiffness and carotid atherosclerosis. DESIGN AND METHOD: A population sample of 248 participants underwent measurements for 24-hour ambulatory BP and nighttime home BP (3 measurements at 2, 3 and 4 hours during 2 nights). We measured ambulatory BP with a Microlife WatchBP O3 device and home BP with a timer-equipped Microlife WatchBP Home N device...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508736/-op-5b-02-pulse-pressure-amplification-and-aortic-reflected-wave-magnitude-but-not-aortic-pressures-or-augmentation-indices-add-to-brachial-pulse-pressure-associations-with-end-organ-changes
#17
G Norton, M J Sibiya, H L Booysen, G Tade, I Ballim, P Sareli, A J Woodiwiss
OBJECTIVE: Although several indices of aortic pressure are associated with cardiovascular damage independent of brachial blood pressure (BP), those indices which enhance associations beyond brachial BP are uncertain. We aimed to identify those aortic pressure indices that best enhance brachial BP relations with end-organ measures. DESIGN AND METHOD: Aortic function was determined using radial applanation tonometry and SphygmoCor software in 1197 community participants...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508596/-op-lb03-07-effects-of-lercanidipine-enalapril-compared-with-amlodipine-enalapril-and-hydrochlorothiazide-enalapril-on-target-organ-damage-and-sympathetic-activity-in-hypertension
#18
C Tsioufis, A Kasiakogias, K Dimitriadis, T Kalos, I Liatakis, D Konstantinidis, E Andrikou, L Nikolopoulou, E Vlachos, K Kyriazopoulos, D Tousoulis
OBJECTIVE: The aim of the study is to compare in essential hypertensives the effects of lercanidipine/enalapril versus amlodipine/enalapril and enalapril/hydrochlorothiazide on various target organ damage end-points as well as on sympathetic nervous system activation during a follow-up period of 3 months. DESIGN AND METHOD: We studied 56 untreated patients with essential hypertension stage II [age: 56 ± 10 years, 30 males, office blood pressure (BP): 148/92 ± 14/11 mmHg] who were randomized to lercanidipine 10 mg/enalapril 20 mg (once daily) or amlodipine 5 mg/enalapril 20 mg (once daily) or enalapril 20 mg/hydrochlorothiazide 12...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27348519/the-association-between-home-vs-ambulatory-night-time-blood-pressure-and-end-organ-damage-in-the-general-population
#19
Annika S Lindroos, Jouni K Johansson, Pauli J Puukka, Ilkka Kantola, Veikko Salomaa, Eeva P Juhanoja, Sam S E Sivén, Pekka Jousilahti, Antti M Jula, Teemu J Niiranen
OBJECTIVE: The aim of this study was to test the agreement between night-time home and night-time ambulatory blood pressure (BP) and to compare their associations with hypertensive end-organ damage for the first time in the general population. METHODS: A population sample of 248 participants underwent measurements for night-time home BP (three measurements on two nights with a timer-equipped home device), night-time ambulatory BP, pulse wave velocity (PWV), carotid intima-media thickness (IMT) and echocardiographic left ventricular mass index (LVMI)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27195237/determinants-and-prognostic-significance-of-the-renal-resistive-index
#20
REVIEW
Nicholas Cauwenberghs, Tatiana Kuznetsova
BACKGROUND: The noninvasive assessment of renal hemodynamics is currently possible by assessing the renal resistive index (RRI) derived from intrarenal Doppler arterial waveforms as (peak systolic velocity - end-diastolic velocity)/peak systolic velocity. In this review, we outline the important determinants of the RRI to clarify the true identity of the RRI and highlight its potential diagnostic and prognostic value in renal and cardiovascular pathology. SUMMARY: Although the RRI was initially considered to reflect intrarenal vascular pathological processes, this index is actually a product of a complex interaction between renal and systemic vascular wall properties and hemodynamic factors...
April 2016: Pulse (Basel, Switzerland)
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