Ahmad El-Hellani, Elyana Hanna, Mehak Sharma, Reagan Blohowiak, Phillip Joseph, Tore Eid, Haleh Nadim, Rachel El-Hage, Rola Salman, Nareg Karaoghlanian, Ayomipo Adeniji, Sally Salam, Farid Talih, Martine Elbejjani, Alison Breland, Thomas Eissenberg, Alan Shihadeh, Stephen R Baldassarri, Soha Talih
INTRODUCTION: Electronic cigarette (EC) use has increased rapidly in the last decade, especially among youth. Regulating nicotine delivery from ECs could help curb youth uptake and leverage EC use in harm reduction yet is complicated by varying device and liquid variables that affect nicotine delivery. Nicotine flux, the nicotine emission rate, is a parameter that incorporates these variables and focuses on the performance rather than the design of an EC. Nicotine flux therefore could be a powerful regulatory tool if it is shown empirically to predict nicotine delivery and subjective effects related to dependence...
2023: PloS One