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Complimentary medicine

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https://www.readbyqxmd.com/read/29696229/total-integrated-performance-excellence-system-tipes-a-true-north-direction-for-a-clinical-trial-support-center
#1
Mike R Sather, Sherry Parsons, Kathy D Boardman, Stuart R Warren, Anne Davis-Karim, Kevin Griffin, Jane A Betterton, Mark S Jones, Stanley H Johnson, Julia E Vertrees, Jan H Hickey, Thelma P Salazar, Grant D Huang
This paper presents the quality journey taken by a Federal organization over more than 20 years. These efforts have resulted in the implementation of a Total Integrated Performance Excellence System (TIPES) that combines key principles and practices of established quality systems. The Center has progressively integrated quality system frameworks including the Malcom Baldrige National Quality Award (MBNQA) Framework and Criteria for Performance Excellence, ISO 9001, and the Organizational Project Management Maturity Model (OPM3), as well as supplemental quality systems of ISO 15378 (packaging for medicinal products) and ISO 21500 (guide to project management) to systematically improve all areas of operations...
March 2018: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29695862/critical-roles-of-trpv2-channels-histamine-h1-and-adenosine-a1-receptors-in-the-initiation-of-acupoint-signals-for-acupuncture-analgesia
#2
Meng Huang, Xuezhi Wang, Beibei Xing, Hongwei Yang, Zheyan Sa, Di Zhang, Wei Yao, Na Yin, Ying Xia, Guanghong Ding
Acupuncture is one of the most promising modalities in complimentary medicine. However, the underlying mechanisms are not well understood yet. We found that in TRPV2 knockout male mice, acupuncture-induced analgesia was suppressed with a decreased activation of mast cells in the acupoints stimulated. The mast cell stabilizer sodium cromolyn could suppress the release of adenosine in the acupoints on male rats. A direct injection of adenosine A1 receptor agonist or histamine H1 receptor agonist increased β-endorphin in the cerebral-spinal fluid in the acute adjuvant arthritis male rats and thus replicated the analgesic effect of acupuncture...
April 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29551069/photoswitching-of-dna-hybridization-using-a-molecular-motor
#3
Anouk S Lubbe, Qing Liu, Sanne J Smith, Jan Willem de Vries, Jos C M Kistemaker, Alex H De Vries, Ignacio Faustino, Zhuojun Meng, Wiktor Szymanski, Andreas Herrmann, Ben L Feringa
Reversible control over the functionality of biological systems via external triggers may be used in future medicine to reduce the need for invasive procedures. Additionally, externally regulated biomacromolecules are now considered as particularly attractive tools in nanoscience and the design of smart materials, due to their highly programmable nature and complex functionality. Incorporation of photoswitches into biomolecules, such as peptides, antibiotics and nucleic acids, has generated exciting results in the past few years...
March 18, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29541970/complimentary-care-when-our-patients-request-to-pray
#4
Cheryl Ann Green
Prayer is viewed in modern medicine as a complimentary alternative treatment. However, to many patients, it is a source of hope and comfort. Patients, when facing illness, advanced disease, disability or death, can benefit from prayer. For healthcare providers, comfort with praying with patients can be deemed as unprofessional conduct or blurred therapeutic boundaries, particularly, when prayer is offered to patients' unsolicited by the patient or their family member(s). Therefore, it is imperative that healthcare providers await the request of prayer by the patient before prayer is initiated...
March 14, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29464520/infrared-spectroscopy-and-imaging-in-stem-cells-and-aging-research
#5
Ceren Aksoy, Feride Severcan
The effect of aging process on stem cell function is crucial because of their critical role in tissue regeneration and repair. The impact of aging on stem cells needs to be understood clearly for the success of clinical application and obtaining desired therapeutic outcome throughout the novel stem cell based therapies. The existing methods used to monitor and characterize the stem cells have some unwanted effects on the properties of stem cells and these methods also do not provide real-time information about cellular conditions...
February 21, 2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29446825/phytomedicines-medicines-derived-from-plants-for-sickle-cell-disease
#6
REVIEW
Oluseyi Oniyangi, Damian H Cohall
BACKGROUND: Sickle cell disease, a common recessively inherited haemoglobin disorder, affects people from sub-Saharan Africa, the Middle East, Mediterranean basin, Indian subcontinent, Caribbean and South America. It is associated with complications and a reduced life expectancy. Phytomedicines (medicine derived from plants in their original state) encompass many of the plant remedies from traditional healers which the populations most affected would encounter. Laboratory research and limited clinical trials have suggested positive effects of phytomedicines both in vivo and in vitro...
February 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29428868/mapping-the-cancer-patient-information-landscape-a-comparative-analysis-of-patient-groups-across-europe-and-north-america
#7
Mark Lawler, Gillian Prue, Ian Banks, Kate Law, Peter Selby, Gordon McVie, Richard Sullivan
AIM: Little is known about how patient groups provide information for patients. We invited 838 patient groups from Europe and North America to participate in an online survey. METHODS: The survey covered: (i) availability, accessibility and quality of information provided; (ii) methods by which patient groups communicate; (iii) ways in which patient groups acquire information and confirm its veracity/accuracy; (iv) how people access information online. RESULTS: European patient groups were significantly less effective in providing medical-related information than their North American counterparts in: clinical trials, potential causes of cancer, medical research, diagnosis/screening, symptoms, treatments (all p < 0...
March 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29413979/effect-of-tinospora-cordifolia-aqua-alcoholic-extract-on-pharmacokinetic-of-glibenclamide-in-rat-an-herb-drug-interaction-study
#8
Rajanikanta Sahu, Tausif Ahmed, Ramchandra Sangana, Ravindra Punde, Bharat Bhusan Subudhi
Tinospora cordifolia (TC) has been used as a complimentary/alternative medicine against diabetes. Considering its potential to modulate metabolic enzymes, Tinospora cordifolia extract (TCE) may influence the metabolism of the antidiabeic drug Glibenclamide following co-administration. Accordingly, this work was undertaken to evaluate impact of TCE on fate of Glibenclamide. Activity of clinically important Cytochrome P450 isoenzymes were inhibited in the order of CYP2C9 > CYP2D6 > CYP2C19 > CYP1A2 > CYP3A4...
March 20, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29404572/association-of-rideshare-based-transportation-services-and-missed-primary-care-appointments-a-clinical-trial
#9
Krisda H Chaiyachati, Rebecca A Hubbard, Alyssa Yeager, Brian Mugo, Stephanie Lopez, Elizabeth Asch, Catherine Shi, Judy A Shea, Roy Rosin, David Grande
Importance: Transportation barriers contribute to missed primary care appointments for patients with Medicaid. Rideshare services have been proposed as alternatives to nonemergency medical transportation programs because of convenience and lower costs. Objective: To evaluate the association between rideshare-based medical transportation and missed primary care appointments among Medicaid patients. Design, Setting, and Participants: In a prospective clinical trial, 786 Medicaid beneficiaries who resided in West Philadelphia and were established primary care patients at 1 of 2 academic internal medicine practices located within the same building were included...
March 1, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29393539/pulsed-gradient-stimulated-echo-pgste-nmr-shows-spatial-dependence-of-fluid-diffusion-in-human-stage-iv-osteoarthritic-cartilage
#10
Sarah E Mailhiot, Sarah L Codd, Jennifer R Brown, Joseph D Seymour, Ronald K June
PURPOSE: Human osteoarthritic (OA) articular cartilage was investigated with spatially resolved pulsed gradient stimulated echo (PGStE) NMR using strong gradients. In this study, the diffusivity of fluid and biopolymer was characterized as a function of depth within human OA cartilage cores. METHODS: One dimensional (1D) spatially resolved diffusion profiles were measured for human OA cartilage using a standard pulsed gradient stimulated echo (PGStE) sequence with the addition of a read imaging gradient...
February 2, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29377216/the-safety-and-efficacy-of-low-dose-naltrexone-in-the-management-of-chronic-pain-and-inflammation-in-multiple-sclerosis-fibromyalgia-crohn-s-disease-and-other-chronic-pain-disorders
#11
REVIEW
Denise K Patten, Bob G Schultz, Daniel J Berlau
Chronic inflammatory diseases are complex to treat and have an impact on a large number of patients. Due to the difficulty of treating these diseases and the great impact on quality of life, patients often seek off-label, complimentary, or alternative medicines to gain relief from symptoms. Low-dose naltrexone has been used off-label for treatment of pain and inflammation in multiple sclerosis, Crohn's disease, fibromyalgia, and other diseases. Naltrexone is a mu-opioid receptor antagonist indicated by the U...
March 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29376121/magnetosensitive-e-skins-with-directional-perception-for-augmented-reality
#12
Gilbert Santiago Cañón Bermúdez, Dmitriy D Karnaushenko, Daniil Karnaushenko, Ana Lebanov, Lothar Bischoff, Martin Kaltenbrunner, Jürgen Fassbender, Oliver G Schmidt, Denys Makarov
Electronic skins equipped with artificial receptors are able to extend our perception beyond the modalities that have naturally evolved. These synthetic receptors offer complimentary information on our surroundings and endow us with novel means of manipulating physical or even virtual objects. We realize highly compliant magnetosensitive skins with directional perception that enable magnetic cognition, body position tracking, and touchless object manipulation. Transfer printing of eight high-performance spin valve sensors arranged into two Wheatstone bridges onto 1...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29302552/complementary-feeding-practices-among-children-aged-6-23-months-in-aligarh-uttar-pradesh
#13
Istiyaq Ahmad, Najam Khalique, Salman Khalil, Urfi, Mohd Maroof
Context: Complementary feeding practices play an important role in the growth and development of the children. Aims: The aim of this study is to determine the prevalence of complementary feeding practices among children aged 6-23 months and its association with various sociodemographic factors. Settings and Design: The study was a community-based, cross-sectional study conducted at field practice area of Urban Health Training Centre and Rural Health Training Centre, Department of Community Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29288920/diagnostic-potential-and-future-directions-of-biomarkers-in-gingival-crevicular-fluid-and-saliva-of-periodontal-diseases-review-of-the-current-evidence
#14
REVIEW
Noha Ayman Ghallab
OBJECTIVES: The holy grail of biomarker research in periodontology is to develop a high impact diagnostics which have a significant impact on clinical decision-making, patient outcomes and healthcare providers. In the field of periodontal diagnostics, oral fluid-based biomarkers have been studied mainly in the gingival crevicular fluid (GCF) and saliva. METHODS: A literature search was performed using the Cochrane library and PubMed databases from 2000 to January 2017...
March 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29214389/using-real-world-data-in-health-technology-assessment-hta-practice-a-comparative-study-of-five-hta-agencies
#15
Amr Makady, Ard van Veelen, Páll Jonsson, Owen Moseley, Anne D'Andon, Anthonius de Boer, Hans Hillege, Olaf Klungel, Wim Goettsch
BACKGROUND: Reimbursement decisions are conventionally based on evidence from randomised controlled trials (RCTs), which often have high internal validity but low external validity. Real-world data (RWD) may provide complimentary evidence for relative effectiveness assessments (REAs) and cost-effectiveness assessments (CEAs). This study examines whether RWD is incorporated in health technology assessment (HTA) of melanoma drugs by European HTA agencies, as well as differences in RWD use between agencies and across time...
March 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29200712/evaluating-the-feasibility-of-five-candidate-dna-barcoding-loci-for-philippine-lasianthus-jack-lasiantheae-rubiaceae
#16
Muhammad Jefte C Arshed, Marcos B Valdez, Grecebio Jonathan D Alejandro
Introduction: The pantropical genus Lasianthus Jack is identified for high phenotypic plasticity making traditional taxonomic identification difficult. Having some members with important medicinal properties, a precise complimentary identification through DNA barcoding is needed for species delineation. Materials and Methods: In this study, 12 samples representing six Philippine Lasianthus species were used to determine the most efficient barcoding loci among the cpDNA markers ( mat K, rbc L, rps 16, and trn T-F) and nrDNA (ITS) based on the criteria of universality, discriminatory power, and resolution of species...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28991769/let-s-go-bananas-gren-bananas-and-their-health-benefits
#17
Vasso Apostolopoulos, Juliana Antonipillai, Kathy Tangalakis, John F Ashton, Lily Stojanovska
Bananas have enormous health benefits as a food for both animals and humans. They have been used as a complimentary medicine to treat pathological conditions since ancient times. Recently, there has been increased interest in the scientific validity of the beneficial effects of bananas in alleviating and treating disease conditions including, ulcers, infections, diabetes, diarrhea, colitis and blood pressure. Herein, we write on the potential therapeutic and functional benefits of certain species of bananas when consumed green as well as considering the properties of extracts from the non-fruit parts of the plant...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28962803/anoxic-ischemic-brain-injury
#18
REVIEW
Jennifer E Fugate
Improvements in cardiopulmonary resuscitation and intensive care medicine have led to declining mortality rates for patients with out-of-hospital cardiac arrest, but overall it is still a minority that achieves good outcomes. Estimating neurologic prognosis for patients that remain comatose after resuscitation remains a challenge and the need for accurate and early prognostic predictors is crucial. A thoughtful approach is required and should take into account information acquired from multiple tests in association with neurologic examination...
November 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28870177/will-chinese-external-therapy-with-compound-tripterygium-wilfordii-hook-f-gel-safely-control-disease-activity-in-patients-with-rheumatoid-arthritis-design-of-a-double-blinded-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Quan Jiang, Xiao-Po Tang, Xian-Chun Chen, Hong Xiao, Ping Liu, Juan Jiao
BACKGROUND: Chinese external therapy (CET) is a topical application with mainly Chinese herb medicine therapy with thousands of years of historical implications and is a clinical routine that is commonly used for relieving joint-related symptoms in patients with arthritis in Chinese hospitals. However, there is a paucity of modern medical evidence to support its effectiveness and safety. Thus, we propose to implement a randomized, double-blinded, placebo-controlled clinical trial in patients with rheumatoid arthritis (RA) using, as the experimental intervention, topical application of a hospital-compounded gel preparation of Tripterygium wilfordii Hook F (TwHF)...
September 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28807165/effect-and-mechanism-of-chinese-herbal-medicine-on-parkinson-s-disease
#20
Bai-Yun Zeng
Parkinson's disease is a progressive neurodegenerative disorder. Although both genetic and environmental factors are implicated in the development of Parkinson's disease, the cause of the disease is still unclear. So far conventional treatments to Parkinson's are symptomatic relief and focused mainly on motor symptoms. Chinese herbal medicine has been used to treat many conditions in China, Korea, Japan, and many Southeast Asian countries for 1000 years. During past a few decades, Chinese herbal medicine has gained wider and increasing acceptance within both public and medical profession due to its effectiveness on many conditions in western countries...
2017: International Review of Neurobiology
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