keyword
MENU ▼
Read by QxMD icon Read
search

Amine

keyword
https://www.readbyqxmd.com/read/28214685/role-of-laxative-and-antioxidant-properties-of-malva-sylvestris-leaves-in-constipation-treatment
#1
Mohamed-Amine Jabri, Dalanda Wannes, Najla Hajji, Mohsen Sakly, Lamjed Marzouki, Hichem Sebai
INTRODUCTION: Mallaw (Malva sylvestris L.) is a medicinal plant who is traditionally being used as an antiulcer, laxative and anti-hemorrhoid, besides of its culinary use as a food in Tunisian cuisine. The present study was carried out to evaluate the protective effect of Malva sylvestris aqueous extract (MSAE) on constipation- induced by loperamide in male Wistar rats. METHODS: Rats were divided into six groups of six animals each: Control, Loperamide (LOP), LOP+ yohimbine (2mg/kg b...
February 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28214676/chiral-aminoquinoline-based-fluorescent-ph-probe-with-large-stokes-shift-for-bioimaging
#2
Yong-Sheng Xie, Xin-Ling Zhang, Kun Xie, Yanmei Zhao, Huan Wu, Jidong Yang
The aminoquinoline derivatives, (R)- and (S)-2-phenyl-2-(quinolin-6-ylamino)ethan-1-ol (R-PEO and S-PEO), were synthesized by a tandem one-pot three-step CN coupling method where Smiles rearrangement was the key procedure. The selected compound R-PEO showed a significant fluorescence enhancement with a turn-on ratio over 98-fold and enabled the real time determination of proton concentration in acidic solution. The fluorescence intensity of R-PEO exhibited strong pH-dependent performance with a large Stokes shift (115nm) and responded linearly to minor pH change within the range of 3...
February 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28214590/green-engineered-biomolecule-capped-silver-and-copper-nanohybrids-using-prosopis-cineraria-leaf-extract-enhanced-antibacterial-activity-against-microbial-pathogens-of-public-health-relevance-and-cytotoxicity-on-human-breast-cancer-cells-mcf-7
#3
U Jinu, M Gomathi, I Saiqa, N Geetha, G Benelli, P Venkatachalam
This research focused on green engineering and characterization of silver (PcAgNPs) and copper nanoparticles (PcCuNPs) using Prosopis cineraria (Pc) leaf extract prepared by using microwave irradiation. We studied their enhanced antimicrobial activity on human pathogens as well as cytotoxicity on breast cancer cells (MCF-7). Biofabricated silver and copper nanoparticles exhibited UV-Visible absorbance peaks at 420 nm and 575 nm, confirming the bioreduction and stabilization of nanoparticles. Nanoparticles were characterized by FTIR, XRD, FESEM, and EDX analysis...
February 15, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28213882/a-standard-mutual-authentication-protocol-for-cloud-computing-based-health-care-system
#4
Prerna Mohit, Ruhul Amin, Arijit Karati, G P Biswas, Muhammad Khurram Khan
Telecare Medical Information System (TMIS) supports a standard platform to the patient for getting necessary medical treatment from the doctor(s) via Internet communication. Security protection is important for medical records (data) of the patients because of very sensitive information. Besides, patient anonymity is another most important property, which must be protected. Most recently, Chiou et al. suggested an authentication protocol for TMIS by utilizing the concept of cloud environment. They claimed that their protocol is patient anonymous and well security protected...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28213380/complex-formation-with-pentraxin-2-regulates-factor-x-plasma-levels-and-macrophage-interactions
#5
Vincent Muczynski, Gabriel Aymé, Véronique Regnault, Marc Vasse, Delphine Borgel, Paulette Legendre, Amine Bazaa, Amélie Harel, Cécile Loubière, Peter J Lenting, Cécile V Denis, Olivier D Christophe
Recently, we have identified scavenger receptor-AI (SR-AI) as a receptor for coagulation factor X (FX), mediating the formation of a FX-reservoir at the macrophage-surface (Muczynski, Blood 2016 127:778). Here, we demonstrate that the FX/SR-AI-complex comprises a third protein, pentraxin-2. The presence of pentraxin-2 is essential to prevent internalization of FX by SR-AI, while the presence of FX is needed to interfere with internalization of pentraxin-2. Binding studies showed that FX, SR-AI and pentraxin-2 independently bind to each other (Kd,app: 0...
February 17, 2017: Blood
https://www.readbyqxmd.com/read/28213325/carbon-dots-based-fret-for-the-detection-of-dna-damage
#6
Jiri Kudr, Lukas Richtera, Kledi Xhaxhiu, David Hynek, Zbynek Heger, Ondrej Zitka, Vojtech Adam
Here, we aimed our attention at the synthesis of carbon dots (C-dots) with the ability to interact with DNA to suggest an approach for the detection of DNA damage. Primarily, C-dots modified with amine moieties were synthesized using the one-step microwave pyrolysis of citric acid in the presence of diethylenetriamine. The C-dots showed strong photoluminescence with a quantum yield of 4%. In addition, the C-dots (2.8±0.8nm) possessed a good colloidal stability and exhibited a positive surface charge (ζ=36mV) at a neutral pH...
February 9, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28213261/a-method-for-the-analysis-of-sugars-in-biological-systems-using-reductive-amination-in-combination-with-hydrophilic-interaction-chromatography-and-high-resolution-mass-spectrometry
#7
Sami Bawazeer, Ali Muhsen Ali, Aliyah Alhawiti, Abedawn Khalaf, Colin Gibson, Jonans Tusiimire, David G Watson
Separation of sugar isomers extracted from biological samples is challenging because of their natural occurrence as alpha and beta anomers and, in the case of hexoses, in their pyranose and furanose forms. A reductive amination method was developed for the tagging of sugars with the aim of it becoming part of a metabolomics work flow. The best separation of the common hexoses (glucose, fructose, mannose and galactose) was achieved when (2)H5-aniline was used as the tagging reagent in combination with separation on a ZICHILIC column...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213162/the-effect-of-lamotrigine-on-learning-in-mice-using-the-passive-avoidance-model
#8
Fatemeh Izadpanah, Fatemeh Arab, Amin Zarghami, Ali Bijani, Sohrab Kazemi, Ali Akbar Moghadamnia
INTRODUCTION: Lamotrigine (LTG) is an antiepileptic drug that inhibits the release of glutamate by blocking sodium channels. The present study was conducted to evaluate the effect of LTG in different stages of memory using a passive avoidance learning task in mice. METHODS: Male albino mice in the weight range 20-25g were used. They were divided into four groups (control group and three groups receiving various doses of LTG). LTG was given in three doses of 10, 25, and 50mg/kg as intraperitoneal (IP) injections...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28212893/traffic-related-air-pollution-impact-on-mouse-brain-accelerates-myelin-and-neuritic-aging-changes-with-specificity-for-ca1-neurons
#9
Nicholas C Woodward, Payam Pakbin, Arian Saffari, Farimah Shirmohammadi, Amin Haghani, Constantinos Sioutas, Mafalda Cacciottolo, Todd E Morgan, Caleb E Finch
Traffic-related air pollution (TRAP) is associated with lower cognition and reduced white matter volume in older adults, specifically for particulate matter <2.5-μm diameter (PM2.5). Rodents exposed to TRAP have shown microglial activation and neuronal atrophy. We further investigated age differences of TRAP exposure, with focus on hippocampus for neuritic atrophy, white matter degeneration, and microglial activation. Young- and middle-aged mice (3 and 18 months female C57BL/6J) were exposed to nanoscale-PM (nPM, <0...
January 13, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28212554/afb1-hepatocarcinogenesis-is-via-lipid-peroxidation-that-inhibits-dna-repair-sensitizes-mutation-susceptibility-and-induces-aldehyde-dna-adducts-at-p53-mutational-hotspot-codon-249
#10
Mao-Wen Weng, Hyun-Wook Lee, Bongkun Choi, Hsiang-Tsui Wang, Yu Hu, Manju Mehta, Dhimant Desai, Shantu Amin, Yi Zheng, Moon-Shong Tang
Aflatoxin B1 (AFB1) contamination in the food chain is a major cause of hepatocellular carcinoma (HCC). More than 60% of AFB1 related HCC carry p53 codon 249 mutations but the causal mechanism remains unclear. We found that 1) AFB1 induces two types of DNA adducts in human hepatocytes, AFB1-8,9-epoxide-deoxyguanosine (AFB1-E-dG) induced by AFB1-E and cyclic α-methyl-γ-hydroxy-1,N2-propano-dG (meth-OH-PdG) induced by lipid peroxidation generated acetaldehyde (Acet) and crotonaldehyde (Cro); 2) the level of meth-OH-PdG is >30 fold higher than the level of AFB1-E-dG; 3) AFB1, Acet, and Cro, but not AFB1-E, preferentially induce DNA damage at codon 249; 4) methylation at -CpG- sites enhances meth-OH-PdG formation at codon 249; and 5) repair of meth-OH-PdG at codon 249 is poor...
February 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212458/chemical-composition-variability-of-essential-oils-of-daucus-gracilis-steinh-from-algeria
#11
Batoul Benyelles, Hocine Allali, Mohamed El Amine Dib, Nassim Djabou, Julien Paolini, Jean Costa
The chemical compositions of 20 Algerian Daucus gracilis essential oils were investigated using GC-FID, GC/MS, and NMR analyses. Altogether, 47 compounds were identified, accounting for 90-99% of the total oil compositions. The main components were linalool (18; 12.5-22.6%), 2-methylbutyl 2-methylbutyrate (20; 9.2-20.2%), 2-methylbutyl isobutyrate (10; 4.2-12.2%), ammimajane (47; 2.6-37.1%), (E)-β-ocimene (15; 0.2-12.8%) and 3-methylbutyl isovalerate (19; 3.3-9.6%). The chemical composition of the essential oils obtained from separate organs was also studied...
February 17, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28212008/correction-to-controlling-first-row-catalysts-amination-of-aryl-and-heteroaryl-chlorides-and-bromides-with-primary-aliphatic-amines-catalyzed-by-a-binap-ligated-single-component-ni-0-complex
#12
Shaozhong Ge, Rebecca A Green, John F Hartwig
No abstract text is available yet for this article.
February 17, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28211692/asymmetric-aziridination-of-n-sulphonyl-ketimines-with-unfunctionalized-ketones-a-one-pot-approach-to-multi-substituted-fused-aziridines
#13
Sheng Zhang, Lijun Li, Lilan Xin, Wenmin Liu, Kun Xu
A highly diastereo- and enantioselective aziridination of N-sulphonyl ketimines with unfunctionalized ketones was reported. In this efficient method, a sequential direct asymmetric Mannich reaction and oxidative C-H amination were involved, which enabled a straightforward route to multisubstituted fused aziridines in one pot. More importantly, two different products could be selectively obtained in the reaction by adding or removing a metal additive.
February 17, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28211231/visible-light-promoted-asymmetric-cross-dehydrogenative-coupling-of-tertiary-amines-to-ketones-by-synergistic-multiple-catalysis
#14
Qi Yang, Long Zhang, Chen Ye, Sanzhong Luo, Li-Zhu Wu, Chen-Ho Tung
Reported herein is an unprecedented photocatalytic asymmetric cross-dehydrogenative coupling reaction between tertiary amines and simple ketones, and it proceeds by synergistic multiple catalysis with substoichiometric amounts of a hydrogen acceptor. This process is enabled by a simple chiral primary amine catalyst through the coupling of a catalytic enamine intermediate and an iminium cation intermediate in situ generated from tetrahydroisoquinoline derivatives by coupled Ru/Co catalysis.
February 17, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28210727/mn-iv-and-mn-v-radical-species-supported-by-the-redox-non-innocent-bis-2-amino-3-5-di-tert-butylphenyl-amine-pincer-ligand
#15
Nicolas Leconte, Jules Moutet, Khrystyna Herasymchuk, Ryan M Clarke, Christian Philouze, Dominique Luneau, Tim Storr, Fabrice Thomas
The electron-rich pincer ligand 1 has been synthesized and chelated to manganese. The octahedral Mn(iv) bis(diiminosemiquinonate) and Mn(v) (diiminobenzoquinone) (diiminosemiquinonate) radicals were structurally characterized.
February 17, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28210709/clinical-outcomes-of-eus-guided-drainage-of-debris-containing-pancreatic-pseudocysts-a-large-multicenter-study
#16
Dennis Yang, Sunil Amin, Susana Gonzalez, Daniel Mullady, Steven A Edmundowicz, John M DeWitt, Mouen A Khashab, Andrew Y Wang, Satish Nagula, Jonathan M Buscaglia, Juan Carlos Bucobo, Mihir S Wagh, Peter V Draganov, Tyler Stevens, John J Vargo, Harshit S Khara, David L Diehl, Rajesh N Keswani, Srinadh Komanduri, Patrick S Yachimski, Anoop Prabhu, Richard S Kwon, Rabindra R Watson, Adam J Goodman, Petros Benias, David L Carr-Locke, Christopher J DiMaio
Background and study aims Data on clinical outcomes of endoscopic drainage of debris-free pseudocysts (PDF) versus pseudocysts containing solid debris (PSD) are very limited. The aims of this study were to compare treatment outcomes between patients with PDF vs. PSD undergoing endoscopic ultrasound (EUS)-guided drainage via transmural stents. Patients and methods Retrospective review of 142 consecutive patients with pseudocysts who underwent EUS-guided transmural drainage (TM) from 2008 to 2014 at 15 academic centers in the United States...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28210466/antimicrobial-effects-of-ferula-gummosa-boiss-gum-against-extended-spectrum-%C3%AE-lactamase-producing-acinetobacter-clinical-isolates
#17
Fatemeh Farid Afshar, Parvaneh Saffarian, Hamideh Mahmoodzadeh Hosseini, Fereshteh Sattarian, Mohsen Amin, Abbas Ali Imani Fooladi
BACKGROUND AND OBJECTIVES: Acinetobacter spp. are important causes of nosocomial infections. They possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (ESBLs). The aim of this study was to determine antibiotic resistance profile of Acinetobacter clinical isolates especially among ESBL-producing strains and to investigate the antimicrobial effects of oleo-gum-resin extract and essential oil of Ferula gummosa Boiss. MATERIALS AND METHODS: 120 Acinetobacter strains were isolated from various clinical samples of hospitalized patients in Baqiyatallah hospital, Tehran during 2011-2012...
August 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28210430/growth-kinetics-and-characterization-of-human-dental-pulp-stem-cells-comparison-between-third-molar-and-first-premolar-teeth
#18
Davood Mehrabani, Parisa Mahdiyar, Kianoosh Torabi, Reza Robati, Shahrokh Zare, Mehdi Dianatpour, Amin Tamadon
BACKGROUND: Dental pulp stem cells (DPSCs) play an important role in tissue regeneration. This study compares the growth kinetics and characterization of third molar and first premolar human DPSCs. MATERIAL AND METHODS: Dental pulp tissues were isolated from human first premolar and third molar teeth and were digested by treating them with collagenase type I. Single-cell suspensions from each dental pulp were seeded in T25 culture flasks and the media were replaced every 3 days until 70% confluence...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28209894/catalytic-intermolecular-hydroaminations-of-unactivated-olefins-with-secondary-alkyl-amines
#19
Andrew J Musacchio, Brendan C Lainhart, Xin Zhang, Saeed G Naguib, Trevor C Sherwood, Robert R Knowles
The intermolecular hydroamination of unactivated alkenes with simple dialkyl amines remains an unsolved problem in organic synthesis. We report a catalytic protocol for efficient additions of cyclic and acyclic secondary alkyl amines to a wide range of alkyl olefins with complete anti-Markovnikov regioselectivity. In this process, carbon-nitrogen bond formation proceeds through a key aminium radical cation intermediate that is generated via electron transfer between an excited-state iridium photocatalyst and an amine substrate...
February 17, 2017: Science
https://www.readbyqxmd.com/read/28209858/illuminating-amination
#20
Travis L Buchanan, Kami L Hull
No abstract text is available yet for this article.
February 17, 2017: Science
keyword
keyword
21703
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"