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https://www.readbyqxmd.com/read/29691962/gastrointestinal-symptoms-in-children-primary-care-and-specialist-interface
#1
REVIEW
Valeria Dipasquale, Domenico Corica, Simone M C Gramaglia, Simona Valenti, Claudio Romano
AIMS: Gastrointestinal symptoms and diseases represent one of the major reasons for paediatricians' requests for specialist consultations and hospital admissions. One fourth of annual medical consultations for children younger than 6 years can be attributed to gastrointestinal symptoms. High-quality guidelines have been validated worldwide to provide clinical recommendations and support healthcare providers' practice. Nevertheless, overall compliance to standards of care is unsatisfactory, and children with gastrointestinal symptoms frequently undergo expensive, useless specialist consultations and laboratory evaluations...
April 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29691955/pharmacist-led-discharge-medication-counselling-a-scoping-review
#2
REVIEW
Aline F Bonetti, Wálleri C Reis, Natália Fracaro Lombardi, Antonio M Mendes, Harli Pasquini Netto, Inajara Rotta, Fernando Fernandez-Llimos, Roberto Pontarolo
RATIONALE, AIMS, AND OBJECTIVES: Discharge medication counselling has produced improved quality of care and health outcomes, especially by reducing medication errors and readmission rates, and improving medication adherence. However, no studies have assembled an evidence-based discharge counselling process for clinical pharmacists. Thus, the present study aims to map the components of the pharmacist-led discharge medication counselling process. METHODS: We performed a scoping review by searching electronic databases (Pubmed, Scopus, and DOAJ) and conducting a manual search to identify studies published up to July 2017...
April 24, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29691244/cross-sectional-study-on-the-prevalence-and-predictors-of-pregnancy-among-women-living-in-hiv-discordant-relationships-in-a-rural-rakai-cohort-uganda
#3
Lydia Jacenta Nakiganda, Anette Agardh, Benedict Oppong Asamoah
OBJECTIVES: This study examines the prevalence of pregnancy in serodiscordant couples and identifies predictors associated with pregnancy in rural Rakai, Uganda. STUDY DESIGN: A population-based cross-sectional study that used data from the Rakai Community Cohort Study (RCCS). SETTING AND PARTICIPANTS: We used data from the RCCS survey round 17 (2015-2016), which included 488 women in serodiscordant relationships. This study was conducted in Rakai district, located in south-western Uganda...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29691197/a-community-pharmacy-intervention-for-opioid-medication-misuse-a-pilot-randomized-clinical-trial
#4
Gerald Cochran, Craig Field, Jordan Karp, Amy L Seybert, Qi Chen, Whitney Ringwald, Valerie Hruschak, Sunita Chickering, Joelle Kincman, Amanda Jaber, Ralph Tarter
OBJECTIVES: Community pharmacy continues to play a crucial role in the national response to the opioid epidemic. The purpose of this article is to describe the protocol for a pilot study that is examining the feasibility and acceptability of the Motivational Intervention-Medication Therapy Management (MI-MTM) model. This study also examines the preliminary clinical effect of MI-MTM for improving opioid medication misuse and patient activation in self-management of health conditions that increase risk for misuse...
April 21, 2018: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29691178/a-higher-altitude-is-an-independent-risk-factor-for-venous-thromboembolisms-after-total-hip-arthroplasty
#5
Dhanur Damodar, Chester J Donnally, Jonathan I Sheu, Tsun Y Law, Martin W Roche, Victor H Hernandez
BACKGROUND: High altitudes lead to physiological changes that may predispose to venous thromboembolisms (VTEs) including deep vein thrombosis and pulmonary embolism (PE). No prior study has evaluated if there is also a higher risk of VTEs for total hip arthroplasties (THAs) performed at higher elevations. The purpose of this retrospective study was to identify if undergoing THA at a higher altitude center (>4000 feet above sea level) is an independent risk factor for a postoperative VTE...
March 27, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29691174/ten-year-mortality-and-revision-after-total-knee-arthroplasty-in-morbidly-obese-patients
#6
Mina Tohidi, Susan B Brogly, Katherine Lajkosz, Heather J Grant, Elizabeth G VanDenKerkhof, Aaron R Campbell
BACKGROUND: Although morbid obesity has been associated with early surgical complications after total knee arthroplasty (TKA), evidence of long-term outcomes is limited. We conducted a population-based study to determine the association between morbid obesity and 10-year survival and revision surgery in patients undergoing primary TKA. METHODS: A cohort study of 9817 patients aged 18-60 years treated with primary TKA from April 1, 2002 to March 31, 2007 was conducted using Ontario administrative health-care databases of universal health-care coverage...
April 4, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29691172/revision-of-unicompartmental-knee-arthroplasty-to-total-knee-arthroplasty-is-it-as-good-as-a-primary-result
#7
Adolph V Lombardi, Mark T Kolich, Keith R Berend, Michael J Morris, David A Crawford, Joanne B Adams
BACKGROUND: Unicompartmental knee arthroplasty (UKA) is touted as a more conservative, bone- and tissue-sparing procedure than total knee arthroplasty (TKA). Similarly, revision of UKA to TKA is generally a simpler procedure than revision of TKA to TKA and can be accomplished with primary TKA components in most cases. The purpose of this study was to review a consecutive series of patients undergoing revision of failed UKA to TKA to determine if etiology is similar to that reported in recent literature and evaluate if the results align more with primary TKA vs revision of TKA to TKA...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29690897/a-qualitative-study-of-safe-abortion-and-post-abortion-family-planning-service-experiences-of-women-attending-private-facilities-in-kenya
#8
Suzanne Penfold, Susy Wendot, Inviolata Nafula, Katharine Footman
BACKGROUND: To inform improvements in safe abortion and post-abortion family planning (PAFP) services, this study aimed to explore the pathways, decision-making, experiences and preferences of women receiving safe abortion and post-abortion family planning (PAFP) at private clinics in western Kenya. METHODS: We conducted semi-structured interviews with 22 women who had recently used a safe abortion service from a private clinic. Interviews explored abortion-seeking behaviour and decision-making, abortion experience, use and knowledge of contraception, experience of PAFP counselling, and perceived facilitators of and challenges to family planning use...
April 24, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29689393/peak-timing-for-complications-following-adult-spinal-deformity-surgery
#9
Alan H Daniels, Shay Bess, Breton Line, Adam E M Eltorai, Daniel B C Reid, Virginie Lafage, Behrooz A Akbarnia, Christopher P Ames, Oheneba Boachie-Adjei, Douglas C Burton, Vedat Deviren, Han Jo Kim, Robert A Hart, Khaled M Kebaish, Eric O Klineberg, Munish Gupta, Gregory M Mundis, Richard A Hostin, Michael O'Brien, Frank J Schwab, Christopher I Shaffrey, Justin S Smith
BACKGROUND: Overall complication rates for adult spinal deformity (ASD) surgery have been reported, however little data exists on the peak timing associated with specific complications. This study quantifies the peak timing for multiple complication types in an ASD cohort at minimum 2-year follow up. METHODS: Multi-center, prospective analysis of all complications following ASD surgery in a consecutively enrolled cohort was performed. Inclusion criteria were ASD, age ≥ 18 years, spinal fusion ≥ 4 levels, and minimum 2-year follow-up...
April 21, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29688494/discordance-between-serum-anti-m%C3%A3-llerian-hormone-concentrations-and-antral-follicle-counts-not-only-technical-issues
#10
M Š Alebic, N Stojanovic, D Dewailly
STUDY QUESTION: Do patient-specific features contribute to the differences between measured serum anti-Müllerian hormone (AMH) concentrations and AMH values expected from the corresponding antral follicle count (AFC)? SUMMARY ANSWER: Patient-specific features contribute to the differences between measured AMH values and AMH values expected from the corresponding AFC (AMHp), potentially through their effect on follicular AMH production. WHAT IS KNOWN ALREADY: Both patient counselling and patient management could be hampered by finding of disagreement between AFC and AMH if both are used for the prediction of ovarian response...
April 24, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29688139/a-multi-site-community-randomized-trial-of-community-health-workers-to-provide-counseling-and-support-for-patients-newly-entering-hiv-care-in-rural-ethiopia-study-design-and-baseline-implementation
#11
Alan R Lifson, Sale Workneh, Abera Hailemichael, Richard F MacLehose, Keith J Horvath, Rose Hilk, Lindsey Fabian, Anne Sites, Tibebe Shenie
BACKGROUND: Although HIV therapy is delivered to millions globally, treatment default (especially soon after entering care) remains a challenge. Community health workers (CHWs) can provide many services for people with HIV, including in rural and resource-limited settings. OBJECTIVES: We designed and implemented a 32 site community randomized trial throughout southern Ethiopia to assess an intervention using CHWs to improve retention in HIV care. METHODS: Sixteen district hospital and 16 local health center HIV clinics were randomized 1:1 to be intervention or control sites...
April 24, 2018: HIV Clinical Trials
https://www.readbyqxmd.com/read/29687313/genetic-counselors-experience-with-and-opinions-on-the-management-of-newborn-screening-incidental-carrier-findings
#12
Kristen Leppert, Katharine Bisordi, Jessica Nieto, Kristin Maloney, Yue Guan, Shannan Dixon, Alena Egense
Newborn screening (NBS) is a public health program whose aim is to identify infants who will be clinically affected with a serious metabolic, genetic, or endocrine disorder; however, the technology utilized by many NBS programs also detects infants who are heterozygous carriers for autosomal recessive conditions. Discussion surrounding disclosure of these incidental carrier findings remains controversial. The purpose of this study was to assess genetic counselors' attitudes about disclosure of carrier status results generated by NBS and to gather data on their experiences with incidental carrier findings...
April 23, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29687268/cost-effectiveness-of-enhancing-a-quit-and-win-smoking-cessation-program-for-college-students
#13
Jonah Popp, John A Nyman, Xianghua Luo, Jill Bengtson, Katherine Lust, Lawrence An, Jasjit S Ahluwalia, Janet L Thomas
OBJECTIVES: We conducted a cost-effectiveness analysis and model-based cost-utility and cost-benefit analysis of increased dosage (3 vs. 1 consecutive contests) and enhanced content (supplemental smoking-cessation counseling) of the Quit-and-Win contest using data from a randomized control trial enrolling college students in the US. METHODS: For the cost-utility and cost-benefit analyses, we used a microsimulation model of the life course of current and former smokers to translate the distribution of the duration of continuous abstinence among each treatment arm's participants observed at the end of the trial (N = 1217) into expected quality-adjusted life-years (QALYs) and costs and an incremental net monetary benefit (INMB)...
April 23, 2018: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29686882/pyosalpinges-after-hysterosalpingography-in-a-patient-with-lower-genital-tract-infection-and-managed-by-laparoscopic-surgery-in-a-resource-low-tertiary-hospital-case-report-and-literature-review
#14
Thomas Obinchemti Egbe, Fidelia Mbi Kobenge, Metogo Mbengono Junette Arlette, Eugene Belley-Priso
Background: Pyosalpinges (a complication of pelvic inflammatory disease) is infection of the fallopian tubes and the morbidity associated with it has major health implications. We are reporting a case of pyosalpinges diagnosed after hysterosalpingography and managed by laparoscopic surgery at the Douala General Hospital, Cameroon. Case presentation: A 29-year-old single woman, an assistant nurse of the Douala tribe in Cameroon. She is G1P0010 and came to our attention because of secondary infertility of three years duration...
2018: Fertility Research and Practice
https://www.readbyqxmd.com/read/29686490/autonomic-instability-in-a-dehydrated-child-on-guanfacine-case-report-and-literature-review
#15
Elizabeth Roach-Fox, Eva Welisch, Amrita Sarpal
An 8-year-old girl on guanfacine extended-release (GXR) for attention-deficit/hyperactivity disorder presented with somnolence, bradycardia and hypotension during a heat wave. No overdose was suspected. She was admitted to the intensive care unit for monitoring and ongoing fluid resuscitation for hypotension. Electrocardiogram showed intermittent atrioventricular dissociation. Upon restarting the drug post-discharge, blood pressures were normal, and follow-up electrocardiograms documented asymptomatic bradycardia but no dissociation...
April 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29686229/prevalence-and-predictors-of-being-lost-to-follow-up-after-transurethral-resection-of-the-prostate
#16
Matteo Fontana, Luca Boeri, Andrea Gallioli, Elisa De Lorenzis, Franco Palmisano, Stefano Paolo Zanetti, Gianluca Sampogna, Giancarlo Albo, Fabrizio Longo, Franco Gadda, Paolo Guido Dell'Orto, Emanuele Montanari
Patient follow-up after transurethral resection of the prostate (TURP) is crucial to evaluate treatment-related outcomes and potential adverse events. We sought to determine the rate of, and factors associated with, patient nonadherence to follow-up after TURP. Data from 180 patients who underwent TURP were analysed. Patient counselling and follow-up were standardized among the cohort. Patients were considered lost to follow-up (LTF) if they were at least 30 days from their first scheduled follow-up appointment...
April 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29686116/practice-guideline-recommendations-summary-disease-modifying-therapies-for-adults-with-multiple-sclerosis-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology
#17
Alexander Rae-Grant, Gregory S Day, Ruth Ann Marrie, Alejandro Rabinstein, Bruce A C Cree, Gary S Gronseth, Michael Haboubi, June Halper, Jonathan P Hosey, David E Jones, Robert Lisak, Daniel Pelletier, Sonja Potrebic, Cynthia Sitcov, Rick Sommers, Julie Stachowiak, Thomas S D Getchius, Shannon A Merillat, Tamara Pringsheim
OBJECTIVE: To develop recommendations for disease-modifying therapy (DMT) for multiple sclerosis (MS). METHODS: A multidisciplinary panel developed DMT recommendations, integrating findings from a systematic review; followed an Institute of Medicine-compliant process to ensure transparency and patient engagement; and developed modified Delphi consensus-based recommendations concerning starting, switching, and stopping DMTs pertinent to people with relapsing-remitting MS, secondary progressive MS, primary progressive MS, and clinically isolated syndromes of demyelination...
April 24, 2018: Neurology
https://www.readbyqxmd.com/read/29686110/-tas2r38-predisposition-to-bitter-taste-associated-with-differential-changes-in-vegetable-intake-in-response-to-a-community-based-dietary-intervention
#18
Larissa Calancie, Thomas C Keyserling, Lindsey Smith Taillie, Kimberly Robasky, Cam Patterson, Alice S Ammerman, Jonathan C Schisler
Although vegetable consumption associates with decreased risk for a variety of diseases, few Americans meet dietary recommendations for vegetable intake. TAS2R38 encodes a taste receptor that confers bitter taste sensing from chemicals found in some vegetables. Common polymorphisms in TAS2R38 lead to coding substitutions that alter receptor function and result in the loss of bitter taste perception. Our study examined whether bitter taste perception TAS2R38 diplotypes associated with vegetable consumption in participants enrolled in either an enhanced or a minimal nutrition counseling intervention...
April 23, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29685865/ethical-issues-for-direct-to-consumer-digital-psychotherapy-apps-addressing-accountability-data-protection-and-consent
#19
Nicole Martinez-Martin, Karola Kreitmair
This paper focuses on the ethical challenges presented by direct-to-consumer (DTC) digital psychotherapy services that do not involve oversight by a professional mental health provider. DTC digital psychotherapy services can potentially assist in improving access to mental health care for the many people who would otherwise not have the resources or ability to connect with a therapist. However, the lack of adequate regulation in this area exacerbates concerns over how safety, privacy, accountability, and other ethical obligations to protect an individual in therapy are addressed within these services...
April 23, 2018: JMIR Mental Health
https://www.readbyqxmd.com/read/29685639/the-elderly-traveller
#20
V Ramos-Sesma, M Górgolas-Hernández Mora, J M Ramos-Rincón
Improved living conditions and advances in medicine have extended life expectancy and quality of life, resulting in an increasing number of elderly travellers. Pathophysiological changes and treatments can reduce the efficacy of vaccines and facilitate drug interactions. Elderly travellers have various characteristics that should be considered when offering pre-trip counselling, which should include proper management of chronic diseases that are susceptible to worsening during the trip, as well as an appropriate study and follow-up after the trip...
April 20, 2018: Revista Clínica Española
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