Nathan E Brummel, Christopher G Hughes, J Brennan McNeil, Pratik P Pandharipande, Jennifer L Thompson, Onur M Orun, Rameela Raman, Lorraine B Ware, Gordon R Bernard, Fiona E Harrison, E Wesley Ely, Timothy D Girard
PURPOSE: The purpose of this study was to determine associations between markers of inflammation and endogenous anticoagulant activity with delirium and coma during critical illness. METHODS: In this prospective cohort study, we enrolled adults with respiratory failure and/or shock treated in medical or surgical intensive care units (ICUs) at 5 centers. Twice per day in the ICU, and daily thereafter, we assessed mental status using the Richmond Agitation Sedation Scale (RASS) and the Confusion Assessment Method-Intensive Care Unit (CAM-ICU)...
April 22, 2024: Intensive Care Medicine