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Morgellon's Disease

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https://www.readbyqxmd.com/read/27789971/morgellons-disease-a-filamentous-borrelial-dermatitis
#1
REVIEW
Marianne J Middelveen, Raphael B Stricker
Morgellons disease (MD) is a dermopathy characterized by multicolored filaments that lie under, are embedded in, or project from skin. Although MD was initially considered to be a delusional disorder, recent studies have demonstrated that the dermopathy is associated with tickborne infection, that the filaments are composed of keratin and collagen, and that they result from proliferation of keratinocytes and fibroblasts in epithelial tissue. Culture, histopathological and molecular evidence of spirochetal infection associated with MD has been presented in several published studies using a variety of techniques...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27730047/morgellons-disease-a-myth-or-reality
#2
Nishita Ranka, Kiran Godse, Nitin Nadkarni, Sharmila Patil, Shweta Agarwal
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27269255/the-first-investigative-science-based-evidence-of-morgellons-psychogenesis
#3
Luca Roncati, Antonietta Morena Gatti, Teresa Pusiol, Francesco Piscioli, Giuseppe Barbolini, Antonio Maiorana
Morgellons disease is an infrequent syndromic condition, that typically affects middle-aged white women, characterized by crawling sensations on and under the skin, associated with itchy rashes, stinging sores, fiber-like filaments emerging from the sores, severe fatigue, concentrating difficulty, and memory loss. The scientific community is prone to believe that Morgellons is the manifestation of various psychiatric syndromes (Munchausen, Munchausen by proxy, Ekbom, Wittmaack-Ekbom). Up until now, no investigative science-based evidence about its psychogenesis has ever been provided...
September 2016: Ultrastructural Pathology
https://www.readbyqxmd.com/read/25879673/exploring-the-association-between-morgellons-disease-and-lyme-disease-identification-of-borrelia-burgdorferi-in-morgellons-disease-patients
#4
Marianne J Middelveen, Cheryl Bandoski, Jennie Burke, Eva Sapi, Katherine R Filush, Yean Wang, Agustin Franco, Peter J Mayne, Raphael B Stricker
BACKGROUND: Morgellons disease (MD) is a complex skin disorder characterized by ulcerating lesions that have protruding or embedded filaments. Many clinicians refer to this condition as delusional parasitosis or delusional infestation and consider the filaments to be introduced textile fibers. In contrast, recent studies indicate that MD is a true somatic illness associated with tickborne infection, that the filaments are keratin and collagen in composition and that they result from proliferation and activation of keratinocytes and fibroblasts in the skin...
2015: BMC Dermatology
https://www.readbyqxmd.com/read/25778952/exploring-the-association-between-morgellons-disease-and-lyme-disease-identification-of-borrelia-burgdorferi-in-morgellons-disease-patients
#5
Marianne J Middelveen, Cheryl Bandoski, Jennie Burke, Eva Sapi, Katherine R Filush, Yean Wang, Agustin Franco, Peter J Mayne, Raphael B Stricker
BACKGROUND: Morgellons disease (MD) is a complex skin disorder characterized by ulcerating lesions that have protruding or embedded filaments. Many clinicians refer to this condition as delusional parasitosis or delusional infestation and consider the filaments to be introduced textile fibers. In contrast, recent studies indicate that MD is a true somatic illness associated with tickborne infection, that the filaments are keratin and collagen in composition and that they result from proliferation and activation of keratinocytes and fibroblasts in the skin...
December 2015: BMC Dermatology
https://www.readbyqxmd.com/read/25192328/morgellons-disease-presenting-as-an-eyelid-lesion
#6
Rasanamar K Sandhu, Eric A Steele
Morgellons disease is characterized by complaints of uncomfortable skin sensations and fibers emanating from nonhealing skin lesions. Morgellons disease is well-known in the dermatology and psychiatry literature, where it is typically considered a subtype of delusional parasitosis, but it has not yet been described in the ophthalmology literature. A patient with self-reported Morgellons disease is presented, who was referred for evaluation of left lower eyelid ectropion. She reported that her skin was infested with fibers that were "trying to get down into the eyelid...
July 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/25073260/a-case-report-highlighting-the-growing-trend-of-internet-based-self-diagnosis-of-morgellon-s-disease
#7
Gino Mortillaro, Christopher Rodgman, Erik Kinzie, Sarah Ryals
"Morgellon's Disease" is a term used to describe a bizarre condition characterized by the belief that strange sensations in the skin are due to filaments called "Morgellon's Bodies."' The focus of this case report is to inform readers of the growing incidence of this psychosomatic condition. Unfortunately, self-diagnosis has become increasingly common because of the widespread coverage on the Internet. While the validity of the diagnosis is in question, the impact on patient's lives is real, often debilitating, and bears more examination...
November 2013: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/24715950/association-of-spirochetal-infection-with-morgellons-disease
#8
Marianne J Middelveen, Divya Burugu, Akhila Poruri, Jennie Burke, Peter J Mayne, Eva Sapi, Douglas G Kahn, Raphael B Stricker
Morgellons disease (MD) is an emerging multisystem illness characterized by skin lesions with unusual filaments embedded in or projecting from epithelial tissue. Filament formation results from abnormal keratin and collagen expression by epithelial-based keratinocytes and fibroblasts. Recent research comparing MD to bovine digital dermatitis, an animal infectious disease with similar skin features, provided clues that spirochetal infection could play an important role in the human disease as it does in the animal illness...
2013: F1000Research
https://www.readbyqxmd.com/read/24671866/information-consent-and-treatment-of-patients-with-morgellons-disease-an-ethical-perspective
#9
Ylva Söderfeldt, Dominik Groß
Morgellons is a medically contested diagnosis with foremost dermatological symptoms. Patients experience fibers emerging from the skin, together with a range of other somatic, psychiatric, and neurological complaints. Within the medical community, it is generally held to be a variation of delusional parasitosis/delusional infestation, which is usually treated with antipsychotics. Little attention has been paid in the literature to the ethical aspects of treating patients with Morgellons disease. The communicative strategies suggested in the literature display significant ethical issues, primarily the use of therapeutic privilege, i...
April 2014: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/23885516/variable-clinical-presentations-of-secondary-delusional-infestation-an-experience-of-six-cases-from-a-psychodermatology-clinic
#10
Ilknur K Altunay, Bilge Ates, Sibel Mercan, Gulsen Tukenmez Demirci, Semra Kayaoglu
OBJECTIVE: Delusional Infestation (DI) is a relatively rare condition with a fixed belief of being infested with living organisms, despite a lack of medical evidence of such infestation. Although it seems to be a psychiatric disease, patients commonly are admitted to dermatology clinics because of skin findings. Psychiatrists can underestimate its prevalance, whereas dermatologists can miss the diagnosis. It should be managed as a psychodermatological disease. Our aim in the study was to evaluate six patients with different clinical presentations of DI and to emphasize some clinical features...
2012: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/23328363/-morgellons-syndrome-a-disease-transmitted-via-the-media
#11
L Misery
No abstract text is available yet for this article.
January 2013: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/23326202/characterization-and-evolution-of-dermal-filaments-from-patients-with-morgellons-disease
#12
Marianne J Middelveen, Peter J Mayne, Douglas G Kahn, Raphael B Stricker
Morgellons disease is an emerging skin disease characterized by formation of dermal filaments associated with multisystemic symptoms and tick-borne illness. Some clinicians hypothesize that these often colorful dermal filaments are textile fibers, either self-implanted by patients or accidentally adhering to lesions, and conclude that patients with this disease have delusions of infestation. We present histological observations and electron microscopic imaging from representative Morgellons disease samples revealing that dermal filaments in these cases are keratin and collagen in composition and result from proliferation and activation of keratinocytes and fibroblasts in the epidermis...
2013: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/23245971/psychosomatic-factors-in-pruritus
#13
Hong Liang Tey, Joanna Wallengren, Gil Yosipovitch
Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects...
January 2013: Clinics in Dermatology
https://www.readbyqxmd.com/read/22545320/new-findings-in-delusions-of-parasitosis
#14
Michael J Fellner
Two new cases are presented with delusions of parasitosis. Both were women, one middle-aged and one elderly, and exhibited classic symptoms of parasites and "strings" in the skin indicative of Morgellons disease. Each had an additional psychiatric disorder: drug addiction to cocaine and senile dementia. They also illustrate the difficulty encountered by the dermatologist in providing adequate therapy because of resistance to psychiatric referral as well as to standard accepted medication. Newer psychotropics, such as risperdal and lexapro, show promise in helping these patients and add to the therapeutic armamentarium of pimozide...
March 2012: Skinmed
https://www.readbyqxmd.com/read/22458994/delusional-infestation-is-typically-comorbid-with-other-psychiatric-diagnoses-review-of-54-patients-receiving-psychiatric-evaluation-at-mayo-clinic
#15
Sara A Hylwa, Ashley A Foster, Jessica E Bury, Mark D P Davis, Mark R Pittelkow, J Michael Bostwick
OBJECTIVE: Delusional infestation, which encompasses both delusions of parasitosis and delusions of infestation with inanimate objects (sometimes called Morgellons disease), has been said to represent a distinct and encapsulated delusion, that is, a stand-alone diagnosis. Anecdotally, we have observed that patients with delusional infestation often have one or more psychiatric comorbid conditions and that delusional infestation should not be regarded as a stand-alone diagnosis. The purpose of this study was to identify whether patients with delusional infestation have psychiatric comorbid conditions...
May 2012: Psychosomatics
https://www.readbyqxmd.com/read/22295070/clinical-epidemiologic-histopathologic-and-molecular-features-of-an-unexplained-dermopathy
#16
Michele L Pearson, Joseph V Selby, Kenneth A Katz, Virginia Cantrell, Christopher R Braden, Monica E Parise, Christopher D Paddock, Michael R Lewin-Smith, Victor F Kalasinsky, Felicia C Goldstein, Allen W Hightower, Arthur Papier, Brian Lewis, Sarita Motipara, Mark L Eberhard
BACKGROUND: Morgellons is a poorly characterized constellation of symptoms, with the primary manifestations involving the skin. We conducted an investigation of this unexplained dermopathy to characterize the clinical and epidemiologic features and explore potential etiologies. METHODS: A descriptive study was conducted among persons at least 13 years of age and enrolled in Kaiser Permanente Northern California (KPNC) during 2006-2008. A case was defined as the self-reported emergence of fibers or materials from the skin accompanied by skin lesions and/or disturbing skin sensations...
2012: PloS One
https://www.readbyqxmd.com/read/22264448/delusional-infestation-clinical-presentation-in-147-patients-seen-at-mayo-clinic
#17
Ashley A Foster, Sara A Hylwa, Jessica E Bury, Mark D P Davis, Mark R Pittelkow, J Michael Bostwick
BACKGROUND: Delusional infestation is the conviction that one's skin is infested with foreign organisms or materials despite contradictory objective evidence. OBJECTIVE: To delineate clinical characteristics of patients presenting with delusional infestation. METHODS: We performed a retrospective study of patients meeting delusional infestation criteria who were seen for diagnosis and treatment in our tertiary care academic medical center (2001-2007)...
October 2012: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/22253541/filament-formation-associated-with-spirochetal-infection-a-comparative-approach-to-morgellons-disease
#18
Marianne J Middelveen, Raphael B Stricker
Bovine digital dermatitis is an emerging infectious disease that causes lameness, decreased milk production, and weight loss in livestock. Proliferative stages of bovine digital dermatitis demonstrate keratin filament formation in skin above the hooves in affected animals. The multifactorial etiology of digital dermatitis is not well understood, but spirochetes and other coinfecting microorganisms have been implicated in the pathogenesis of this veterinary illness. Morgellons disease is an emerging human dermopathy characterized by the presence of filamentous fibers of undetermined composition, both in lesions and subdermally...
2011: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/22250620/dermatologic-infestations
#19
REVIEW
Eugenia Shmidt, Jacob Levitt
Head lice are transmitted by head to head contact. Optimal therapy includes malathion lotion 0.5% repeated in one week left on for 30 minutes to 8 hours. Spinosad topical suspension 0.9% repeated in one week left on for 10 minutes is another option. Scabies is transmitted mainly by direct contact but also via heavily infested fomites due to crusted scabies. Permethrin 5% cream to the body repeated in four days is often sufficient; however, scalp treatment with malathion lotion 0.5% is helpful in crusted scabies and in infested children...
February 2012: International Journal of Dermatology
https://www.readbyqxmd.com/read/21933231/delusional-infestation-with-unusual-pathogens-a-report-of-three-cases
#20
P Dewan, J Miller, C Musters, R E Taylor, A P Bewley
Delusional infestation (DI) is a psychiatric disorder characterized by a fixed, false belief that the patient is infested with extracorporeal agents. It is known by several names, including the more commonly used term 'delusional parasitosis'. The psychiatric disease is responsible for the cutaneous pathology. About 90% of patients with DI seek help from dermatologists, and most reject psychiatric referral. Thus, effective management requires incorporation of psychiatric principles. We report three cases of DI with inanimate materials, and examine 'Morgellons' disease...
October 2011: Clinical and Experimental Dermatology
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