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Nancy Reims, Silke Tophoven
OBJECTIVE: The study examines employment prospects of persons who participate in further and re-training measures in the context of vocational rehabilitation in the responsibility of the Federal Employment Agency (FEA). METHODS: Using administrative data of the FEA (RehaPro), we focus on persons completing vocational rehabilitation between 2009 and 2012 (N=21,772). We employ event history analysis to present time and extent of employment transition and their sustainability...
June 2018: Die Rehabilitation
Takashi Kunihara, Olaf Wendler, Kerstin Heinrich, Ryota Nomura, Hans-Joachim Schäfers
BACKGROUND:  The optimal choice of conduit and configuration for coronary artery bypass grafting (CABG) in diabetic patients remains somewhat controversial, even though arterial grafts have been proposed as superior. We attempted to clarify the role of complete arterial revascularization using the left internal thoracic artery (LITA) and the radial artery (RA) alone in "T-Graft" configuration on long-term outcome. METHODS AND RESULTS:  From 1994 to 2001, 104 diabetic patients with triple vessel disease underwent CABG using LITA/RA "T-Grafts" (Group-A)...
June 20, 2018: Thoracic and Cardiovascular Surgeon
Alla Bezhentseva, Harpreet Singh, Randy J Boudrieau
OBJECTIVE:  This article describes corrective antebrachiocarpal re-alignment and arthrodesis for bilateral radial hemimelia (radial agenesis) in an 8-month-old domestic short-haired cat. METHODS:  Bilateral forelimb deformity of ulnocarpal varus with complete luxation and rotation of the antebrachiocarpal joint spaces, and joint contracture, was observed. Several carpal bones and metacarpal bones I and II and their associated phalanges were absent. Abnormal ambulation and weight bearing on the dorsolateral part of the manus were present...
June 20, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
Jing Qu, Lanyan Zhu, Zijing Zhou, Ping Chen, Shuyan Liu, Morgan L Locy, Victor J Thannickal, Yong Zhou
RATIONALE: Desmoplakin (DSP), the most abundant component of desmosomes which maintain the mechanical integrity of epithelium, is a GWAS-identified genetic risk locus in human idiopathic pulmonary fibrosis (IPF). IPF subjects express a significantly higher level of DSP than control subjects. OBJECTIVES: Determine potential mechanisms by which DSP is regulated in lung fibrosis Methods: Matrigel-coated soft and stiff polyacrylamide gels were made to simulate the stiffness of normal and fibrotic lungs...
June 20, 2018: American Journal of Respiratory and Critical Care Medicine
Eric A Miller, Yara Jabbour Al Maalouf, Hadley D Sikes
In this work, we characterize the impact of large-volume processing upon the analytical sensitivity of flow-through paper-based immunoassays. Larger sample volumes feature greater molar quantities of available analyte, but the assay design principles which would enable the rapid collection of this dilute target are ill-defined. We developed a finite-element model to explore the operat-ing conditions under which processing large sample volumes via pressure-driven convective flow would yield improved binding signal...
June 20, 2018: Analytical Chemistry
Akira Shiono, Jiro Kogo, Hiroki Sasaki, Ryo Yomoda, Tatsuya Jujo, Naoto Tokuda, Yasushi Kitaoka, Hitoshi Takagi
PURPOSE: To examine the relationship between optical coherence tomography (OCT) images and clinical course in eyes with branch retinal vein occlusion (BRVO) treated with intravitreal ranibizumab injection (IVR). DESIGN: Prospective cohort study. PARTICIPANTS: Thirty eyes of 30 patients with BRVO treated with IVR. METHODS: All patients received 1 initial IVR followed by repeated injections in the pro re nata (PRN) regimen...
2018: PloS One
Tyler Keeley, Shengchen Lin, Daniel K Lester, Eric K Lau, Shengyu Yang
The fucose salvage pathway is a two-step process in which mammalian cells transform L-fucose into GDP-L-fucose, a universal fucose donor used by fucosyltransferases to modify glycans. Emerging evidence indicates the fucose salvage pathway and the fucosylation of proteins are altered during melanoma progression and metastasis. However the underlying mechanisms are not completely understood. Here, we report that the fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation by promoting α-1,2 fucosylation...
2018: PloS One
E V Rosseĭkin, E E Kobzev, O V Popyl'kova, S S Durmanov, V V Bazylev
Death in patients with postinfarction aneurysms of the left ventricle (LV) is mainly caused by life-threatening ventricular arrhythmias - ventricular tachycardias (VTs) and ventricular fibrillations (VFs). Surgical reconstruction of the LV may potentially lead to disruption of the re-entry mechanism, lying at the basis of ventricular tachyarrhythmias. A series of authors demonstrated high efficacy of such procedures as endocardectomy and radiofrequency ablation of the borderline zone of the LV. But high incidence of relapses, difficulty detecting the localization of VT and performing radiofrequency ablation (RFA), as well as high incidence of spontaneous and induced VTs in patients with postinfarction aneurysms of the LV have preserved dissatisfaction with the currently existing techniques...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
Ç Karaca, K-A Dere, N Er, A Aktaş, E Tosun, O-T Köseoğlu, A Usubütün
BACKGROUND: Odontogenic keratocysts have been reported with high recurrence rates in the literature so various treatment modalities from simple enucleation to resection have been performed to achieve the cure. The purpose of this retrospective study was to investigate the recurrence rate of odontogenic keratocysts (OKCs) treated by enucleation and peripheral ostectomy. MATERIAL AND METHODS: An electronic search of the database of the Hacettepe University, Faculty of Medicine, Department of Pathology, was undertaken to identify patients histologically diagnosed with OKCs treated at Department of Oral and Maxillofacial Surgery between 2001 and 2015...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
Jan Huebinger, Markus Grabenbauer
Reduction or complete prevention of ice crystal formation during freezing of biological specimens is mandatory for two important biological applications: (1) cryopreservation of living cells or tissues for long-term storage, and (2) cryo-fixation for ultrastructural investigations by electron microscopy. Here, a protocol that is fast, easy-to-use, and suitable for both cryo-fixation and cryopreservation is described. Samples are rapidly cooled in tightly sealed metal tubes of high thermal diffusivity and then plunged into a liquid cryogen...
June 2018: Current Protocols in Cell Biology
Sonia Grimbuhler, Jean-François Viel
The proper use of personal protective equipment (PPE) plays an important role in reducing exposure to pesticides in vineyard farming activities, including re-entry tasks. However, discomfort from clothing systems may increase the physiological burden on workers. We compared the physiological burdens of vineyard workers wearing three different types of PPE during canopy management in field humid conditions while accounting for occupational, climatic, and geographical environments. The study was conducted in the Bordeaux vineyards of southern France during June 2012...
June 19, 2018: Annals of Work Exposures and Health
Amélie Mathieu, Tiphaine Vidal, Alexandra Jullien, QiongLi Wu, Camille Chambon, Benoit Bayol, Paul-Henry Cournède
Background and Aims: Functional-structural plant models (FSPMs) describe explicitly the interactions between plants and their environment at organ to plant scale. However, the high level of description of the structure or model mechanisms makes this type of model very complex and hard to calibrate. A two-step methodology to facilitate the calibration process is proposed here. Methods: First, a global sensitivity analysis method was applied to the calibration loss function...
June 19, 2018: Annals of Botany
Hiroyuki Oshika, Yukihide Koyama, Masataka Taguri, Koichi Maruyama, Go Hirabayashi, Shoko Merrit Yamada, Masashi Kohno, Tomio Andoh
BACKGROUND: It is very rare but challenging to perform emergency airway management for accidental extubation in a patient whose head and neck are fixed in the prone position when urgently turning the patient to the supine position would be unsafe. The authors hypothesized that tracheal intubation with a videolaryngoscope would allow effective airway rescue in this situation compared with a supraglottic airway device and designed a randomized crossover manikin study to test this hypothesis...
June 2018: Medicine (Baltimore)
Xingfu Huang, Yanjia Chen, Zheng Huang, Liwei He, Shenrong Liu, Xiaojiang Deng, Yongsheng Wang, Rucheng Li, Dingli Xu, Jian Peng
Several studies have reported the efficacy of a zero-fluoroscopy approach for catheter radiofrequency ablation of arrhythmias in a digital subtraction angiography (DSA) room. However, no reports are available on the ablation of arrhythmias in the absence of DSA in the operating room. To investigate the efficacy and safety of catheter radiofrequency ablation for arrhythmias under the guidance of a Carto 3 three-dimensional (3D) mapping system in an operating room without DSA. Patients were enrolled according to the type of arrhythmia...
June 2018: Medicine (Baltimore)
Chandler W Rundle, Sharon E Jacob, Brian C Machler
: Carmine is a widely used "natural" food additive that has been reported to provoke both an immediate hypersensitivity and a delayed systemic response with cutaneous expression. Systemic contact dermatitis describes the hypersensitivity reaction following systemic re-exposure of the inciting allergen in previously sensitized individuals. In individuals with recalcitrant dermatitis and a positive carmine intolerance history and/or patch test, it is important to consider a trial topical and dietary elimination of carmine-associated products and foods...
June 19, 2018: Dermatitis
Lim Beng Leong, Ng Wei Ming, Lee Wei Feng
We reviewed the use of noninvasive ventilation (NIV) versus high flow nasal cannula (HFNC) oxygen in adult acute respiratory failure (ARF). We searched major databases and included randomized trials comparing at least NIV with HFNC or NIV+HFNC with NIV in ARF. Primary outcomes included intubation/re-intubation rates. Secondary outcomes were ICU mortality and morbidities. Five trials were included; three compared HFNC with NIV, one compared HFNC, NIV and oxygen whereas one compared HFNC+NIV with NIV. Patients had hypoxaemic ARF (PaO2/FiO2≤300 mmHg)...
June 19, 2018: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
Dong Wook Kwon, Dong Ho Kim, Sung Chang Hong
The effect of antimony on the selective catalytic reduction (SCR) performance and SO2 durability of V-Sb/Ti was investigated. The physicochemical characteristics of catalyst were characterized by various techniques, including Brunauer-Emmett-Teller (BET) surface area analysis, X-ray diffraction (XRD), NH3 /SO2 -temperature programmed desorption (TPD), diffuse reflectance infrared Fourier transform spectroscopy (DRIFTs), X-ray photoelectron spectroscopy (XPS), and H2 -temperature programmed reduction (H2 -TPR)...
June 20, 2018: Environmental Technology
Hao Jiang, Jiangtao Jia, Aleksander Shkurenko, Zhijie Chen, Karim Adil, Youssef Belmabkhout, Lukasz J Weselinski, Ayalew H Assen, Dong-Xu Xue, Michael O'Keeffe, Mohamed Eddaoudi
Rational design and construction of MOFs with intricate structural complexity are of prime importance in reticular chemistry. We report our latest addition to the design toolbox in reticular chemistry, namely the concept of merged-nets based on merging two edge-transitive nets into a minimal edge-transitive net for the rational construction of intricate mixed-linker MOFs. In essence, a valuable net for design enclosing two edges (not related by symmetry) is rationally generated by merging two edge-transitive nets, namely (3,6)-coordinated spn and 6-coordinated hxg...
June 20, 2018: Journal of the American Chemical Society
Tommaso Jucker, Bonnie Wintle, Gorm Shackelford, Pierre Bocquillon, Jan Laurens Geffert, Tim Kasoar, Eszter Kovacs, Hannah S Mumby, Chloé Orland, Judith Schleicher, Eleanor R Tew, Aiora Zabala, Tatsuya Amano, Alexandra Bell, Boris Bongalov, Josephine M Chambers, Colleen Corrigan, América P Durán, Leslie-Anne Duvic-Paoli, Caroline Emilson, Jéssica Fonseca da Silva, Emma E Garnett, Elizabeth J Green, Miriam K Guth, Andrew Hacket-Pain, Amy Hinsley, Javier Igea, Martina Kunz, Sarah H Luke, William Lynam, Philip A Martin, Matheus H Nunes, Nancy Ockendon, Aly Pavitt, Charlotte L R Payne, Victoria Plutshack, Tim T Rademacher, Rebecca J Robertson, David C Rose, Anca Serban, Benno I Simmons, Erik J S Emilson, Catherine Tayleur, Claire F R Wordley, Nibedita Mukherjee
In 2008, a group of conservation scientists compiled a list of 100 priority questions for the conservation of the world's biodiversity [Sutherland et al. (2009) Conservation Biology, 23, 557-567]. However, now almost a decade later, no one has yet published a study gauging how much progress has been made in addressing these 100 high-priority questions in the peer-reviewed literature. Here we take a first step toward re-examining the 100 questions and identify key knowledge gaps that still remain. Through a combination of a questionnaire and a literature review, we evaluated each of the 100 questions on the basis of two criteria: relevance and effort...
June 20, 2018: Conservation Biology: the Journal of the Society for Conservation Biology
Shimeles Addisu Kitte, Muhammad Nadeem Zafar, Yuriy T Zholudov, Xiangui Ma, Anaclet Nsabimana, Wei Zhang, Guobao Xu
H2O2 is frequently used at high concentrations in various applications. It is very challenging to detect high concentrations of H2O2 and to eliminate oxygen interference for H2O2 detection through electrochemical reduction. In the present investigation, the electrochemistry of H2O2 at stainless steel electrode has been carried out for the first time. A cathodic peak for H2O2 re-duction was observed at about -0.40 V and no cathodic peak for dissolved oxygen reduction was observed on type 304 stainless steel electrode...
June 20, 2018: Analytical Chemistry
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