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https://www.readbyqxmd.com/read/28340449/right-hemisphere-pitch-mismatch-negativity-reduction-in-patients-with-major-depression-an-meg-study
#1
Noriaki Hirakawa, Yoji Hirano, Itta Nakamura, Shogo Hirano, Jinya Sato, Naoya Oribe, Takefumi Ueno, Shigenobu Kanba, Toshiaki Onitsuka
BACKGROUND: The mismatch negativity (MMN) component of the event-related potential and its magnetic counterpart, the MMNm, are generated by a mismatch between the physical features of a deviant stimulus and a neuronal sensory-memory trace produced by repetitive standard stimuli. Deficits in the MMN/MMNm have been reported in patients with major depression; however, the results are inconsistent. The present study investigated the pitch-MMNm in patients with major depression using whole-head 306-channel magnetoencephalography (MEG)...
March 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28336337/mismatch-negativity-as-a-potential-neurobiological-marker-of-early-stage-alzheimer-disease-and-vascular-dementia
#2
Shixiang Jiang, Chang Yan, Zhengxue Qiao, Haiqian Yao, Shiquan Jiang, Xiaohui Qiu, Xiuxian Yang, Deyu Fang, Yanjie Yang, Limei Zhang, Lina Wang, Liming Zhang
Alzheimer's disease (AD) and vascular dementia (VD) are serious, irreversible forms of cognitive impairment, which means that an early diagnosis is essential to slow down their progression. One potential neurophysiological biomarker of these diseases is the mismatch negativity (MMN) event-related potentials (ERP) component, which reflects an automatic detection mechanism at the pre-attentive stages of information processing. We evaluated the auditory MMN response in individuals from two patient groups: those in the prodromal stages of AD (P-AD) and those in the prodromal stages of VD (P-VD)...
March 20, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28325011/research-on-eeg-features-of-attended-unattended-vigilance
#3
Chang Sun, Runge Chen, Miao Tian, Xingwei An, Hongzhi Qi, Minpeng Xu, Xuemin Wang, Dong Ming, Peng Zhou
Vigilance refers to the brain alertness to objective things, including the concentration of attention and the capability to response emergencies. It is of great importance to study vigilance monitoring to avoid accidents caused by decrease of vigilance. In this study, traditional Mackworth Clock Test (MCT) was modified to induce decline of attended and unattended vigilance. We analyzed EEG features in different levels of attended vigilance and assessed unattended vigilance by amplitude of mismatch negative (MMN) which can be evoked by audio odd ball stimulations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28321179/neurophysiological-and-behavioral-responses-of-mandarin-lexical-tone-processing
#4
Yan H Yu, Valerie L Shafer, Elyse S Sussman
Language experience enhances discrimination of speech contrasts at a behavioral- perceptual level, as well as at a pre-attentive level, as indexed by event-related potential (ERP) mismatch negativity (MMN) responses. The enhanced sensitivity could be the result of changes in acoustic resolution and/or long-term memory representations of the relevant information in the auditory cortex. To examine these possibilities, we used a short (ca. 600 ms) vs. long (ca. 2,600 ms) interstimulus interval (ISI) in a passive, oddball discrimination task while obtaining ERPs...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28320129/immunoglobulin-therapy-in-the-treatment-of-multifocal-motor-neuropathy
#5
REVIEW
Aditya Kumar, Huned S Patwa, Richard J Nowak
Multifocal motor neuropathy (MMN) is a chronic immune-mediated disorder leading to slowly progressive muscle weakness and wasting. Current treatments are aimed at modulating the immune system in order to avoid further decline and to maintain functional status. Intravenous immunoglobulin (IVIg) is widely used in the treatment of immune-mediated disorders and is the only treatment approved for MMN. While patients do remain stable with maintenance IVIg treatment, most patients will slowly deteriorate over many years...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28318835/improvement-in-mismatch-negativity-generation-during-d-serine-treatment-in-schizophrenia-correlation-with-symptoms
#6
Joshua T Kantrowitz, Michael L Epstein, Migyung Lee, Nayla Lehrfeld, Karen A Nolan, Constance Shope, Eva Petkova, Gail Silipo, Daniel C Javitt
BACKGROUND: Deficits in N-methyl-d-aspartate-type (NMDAR) function contribute to symptoms and cognitive dysfunction in schizophrenia. The efficacy of NMDAR agonists in the treatment of persistent symptoms of schizophrenia has been variable, potentially reflecting limitations in functional target engagement. We recently demonstrated significant improvement in auditory mismatch negativity (MMN) with once-weekly treatment with d-serine, a naturally occurring NMDAR glycine-site agonist. This study investigates effects of continuous (daily) NMDAR agonists in schizophrenia/schizoaffective disorder...
March 17, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28314681/duration-and-frequency-mismatch-negativity-shows-no-progressive-reduction-in-early-stages-of-psychosis
#7
Daisuke Koshiyama, Kenji Kirihara, Mariko Tada, Tatsuya Nagai, Shinsuke Koike, Motomu Suga, Tsuyoshi Araki, Kiyoto Kasai
The auditory mismatch negativity (MMN) is a component of event-related potentials, which is being increasingly recognized as a candidate biomarker for early stages of psychosis. Although previous cross-sectional studies have demonstrated small MMN amplitude in early stages of psychosis, it remains unknown whether small MMN amplitude is due to progressive reduction during the early course. In this study, we investigated longitudinal changes of MMN in early stages of psychosis. Participant included 14 patients with first-episode psychosis (FEP), 16 individuals with ultra-high risk (UHR), and 16 healthy control subjects (HC)...
March 14, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28298889/cortical-sensitivity-to-guitar-note-patterns-eeg-entrainment-to-repetition-and-key
#8
David A Bridwell, Emily Leslie, Dakarai Q McCoy, Sergey M Plis, Vince D Calhoun
Music is ubiquitous throughout recent human culture, and many individual's have an innate ability to appreciate and understand music. Our appreciation of music likely emerges from the brain's ability to process a series of repeated complex acoustic patterns. In order to understand these processes further, cortical responses were measured to a series of guitar notes presented with a musical pattern or without a pattern. ERP responses to individual notes were measured using a 24 electrode Bluetooth mobile EEG system (Smarting mBrainTrain) while 13 healthy non-musicians listened to structured (i...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28293514/platysma-motor-nerve-transfer-for-restoring-marginal-mandibular-nerve-function
#9
Andres Rodriguez-Lorenzo, David Jensson, Wolfgang J Weninger, Melanie Schmid, Stefan Meng, Chieh-Han John Tzou
BACKGROUND: Injuries of the marginal mandibular nerve (MMN) of the facial nerve result in paralysis of the lower lip muscle depressors and an asymmetrical smile. Nerve reconstruction, when possible, is the method of choice; however, in cases of long nerve gaps or delayed nerve reconstruction, conventional nerve repairs may be difficult to perform or may provide suboptimal outcomes. Herein, we investigate the anatomical technical feasibility of transfer of the platysma motor nerve (PMN) to the MMN for restoration of lower lip function, and we present a clinical case where this nerve transfer was successfully performed...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28288158/stimulus-specific-adaptation-in-a-recurrent-network-model-of-primary-auditory-cortex
#10
Tohar S Yarden, Israel Nelken
Stimulus-specific adaptation (SSA) occurs when neurons decrease their responses to frequently-presented (standard) stimuli but not, or not as much, to other, rare (deviant) stimuli. SSA is present in all mammalian species in which it has been tested as well as in birds. SSA confers short-term memory to neuronal responses, and may lie upstream of the generation of mismatch negativity (MMN), an important human event-related potential. Previously published models of SSA mostly rely on synaptic depression of the feedforward, thalamocortical input...
March 13, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28283845/brief-report-biological-sound-processing-in-children-with-autistic-spectrum-disorder
#11
Melissa Lortie, Léa Proulx-Bégin, Dave Saint-Amour, Dominique Cousineau, Hugo Théoret, Jean-François Lepage
There is debate whether social impairments in autism spectrum disorder (ASD) are truly domain-specific, or if they reflect generalized deficits in lower-level cognitive processes. To solve this issue, we used auditory-evoked EEG responses to assess novelty detection (MMN component) and involuntary attentional orientation (P3 component) induced by socially-relevant, human-produced, biological sounds and acoustically-matched control stimuli in children with ASD and controls. Results show that early sensory and novelty processing of biological stimuli are preserved in ASD, but that automatic attentional orientation for biological sounds is markedly altered...
March 10, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28275100/maternal-supplementation-with-small-quantity-lipid-based-nutrient-supplements-compared-with-multiple-micronutrients-but-not-with-iron-and-folic-acid-reduces-the-prevalence-of-low-gestational-weight-gain-in-semi-urban-ghana-a-randomized-controlled-trial
#12
Seth Adu-Afarwuah, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Mamane Zeilani, Mary Arimond, Stephen A Vosti, Kathryn G Dewey
Background: It is unclear whether maternal supplementation with small-quantity lipid-based nutrient supplements (SQ-LNSs; 118 kcal/d) affects maternal weight.Objective: We compared several secondary anthropometric measures between 3 groups of women in the iLiNS (International Lipid-based Nutrient Supplements)-DYAD trial in Ghana.Methods: Women (n = 1320; <20 wk of gestation) were randomly assigned to receive 60 mg Fe + 400 μg folic acid/d (IFA), 18 vitamins and minerals/d [multiple micronutrients (MMNs)], or 20 g SQ-LNSs with 22 micronutrients/d (LNS) during pregnancy and a placebo (200 mg Ca/d), MMNs, or SQ-LNSs, respectively, for 6 mo postpartum...
March 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28268635/multi-domain-feature-selection-in-auditory-mismatch-negativity-via-parafac-based-template-matching-approach
#13
Saeed Pouryazdian, Andrew Chang, Dan J Bosnyak, Laurel J Trainor, Soosan Beheshti, Sridhar Krishnan
MisMatch Negativity (MMN) is a small event-related potential (ERP) that provide an index of sensory learning and perceptual accuracy for the cognitive research. Group-level analysis plays an important role for detecting differences at group or condition level, especially when the signal-to-noise ratio is low. Tensor factorization has provided a framework for group-level analysis of ERPs by exploiting more information of brain responses in more domains simultaneously. A 4-way ERP tensor of time × frequency × channel × subjects/condition is generated and decomposed via PARAFAC...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268485/automatic-and-continuous-assessment-of-erps-for-mismatch-negativity-detection
#14
Narges Armanfard, Majid Komeili, James P Reilly, Richard Mah, John F Connolly
Accurate and fast detection of event related potential (ERP) components is an unresolved issue in neuroscience and critical health care. Mismatch negativity (MMN) is a component of the ERP to an odd stimulus in a sequence of identical stimuli which has good correlation with coma awakening. All of the previous studies for MMN detection are based on visual inspection of the averaged ERPs (over a long recording time) by a skilled neurophysiologist. However, in practical situations, such an expert may not be available or familiar with all aspects of evoked potential methods...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263679/effects-of-visual-game-experience-on-auditory-processing-speed
#15
Kyung Soon Shin, Yoon Kyoung Yim, Yuwon Kim, Soowon Park, Jun-Young Lee
Games are one of the fastest growing and most exciting forms of entertainment. Whether casual mobile game playing has a cognitive, physiological, or behavioral effect on players whose game use is not pathological is unknown. Here we explored whether preattentive auditory processing is linked to the behavioral inhibition system (BIS) in frequent and infrequent game players. A total of 74 subjects who were enrolled in our study were divided into two groups, 40 subjects were frequent gamers and 34 subjects were age-, gender-, IQ-, and education-matched infrequent gamers...
March 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28247405/your-brain-on-bikes-p3-mmn-n2b-and-baseline-noise-while-pedaling-a-stationary-bike
#16
Joanna E M Scanlon, Alex J Sieben, Kevin R Holyk, Kyle E Mathewson
Increasingly, there is a trend to measure brain activity in more ecologically realistic scenarios. Normally, the confines of the laboratory and sedentary tasks mitigate sources of electrical noise on EEG measurement. Moving EEG outside of the lab requires understanding of the impact of complex movements and activities on traditional EEG and ERP measures. Here, we recorded EEG with active electrodes while participants were either riding or sitting on a stationary bike in an electrical and sound-attenuated chamber in the lab...
March 1, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28235554/mismatch-field-latency-but-not-power-may-mark-a-shared-autistic-and-schizotypal-trait-phenotype
#17
Talitha C Ford, Will Woods, David P Crewther
The auditory mismatch negativity (MMN), a preattentive processing potential, and its magnetic counterpart (MMF) are consistently reported as reduced in schizophrenia and autism spectrum disorders. This study investigates whether MMF characteristics differ between subclinically high and low scorers on the recently discovered shared autism and schizophrenia phenotype, Social Disorganisation. A total of 18 low (10 females) and 19 high (9 females) Social Disorganisation scorers underwent magnetoencephalography (MEG) during a MMF paradigm of 50ms standard (1000Hz, 85%) and 100ms duration deviant tones...
February 21, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28229115/data-on-the-auditory-duration-mismatch-negativity-for-different-sound-pressure-levels-and-visual-perceptual-loads
#18
Stefan Wiens, Malina Szychowska, Rasmus Eklund, Mats E Nilsson
The data presented in this article are related to our research article entitled "Effects of sound pressure level and visual perceptual load on the auditory mismatch negativity" (M. Szychowska, R. Eklund, M.E. Nilsson, S. Wiens, 2016) [1]. The duration MMN was recorded at three sound pressure levels (SPLs) during two levels of visual perceptual load. In an oddball paradigm (standard=75 ms, deviant=30 ms, within-subjects design), participants were presented with tones at 56, 66, or 76 dB SPL (between-subjects design)...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28227552/research-on-eeg-features-of-attended-unattended-vigilance
#19
Chang Sun, Runge Chen, Miao Tian, Xingwei An, Hongzhi Qi, Minpeng Xu, Xuemin Wang, Dong Ming, Peng Zhou, Chang Sun, Runge Chen, Miao Tian, Xingwei An, Hongzhi Qi, Minpeng Xu, Xuemin Wang, Dong Ming, Peng Zhou, Miao Tian, Minpeng Xu, Hongzhi Qi, Runge Chen, Dong Ming, Chang Sun, Xingwei An, Peng Zhou, Xuemin Wang
Vigilance refers to the brain alertness to objective things, including the concentration of attention and the capability to response emergencies. It is of great importance to study vigilance monitoring to avoid accidents caused by decrease of vigilance. In this study, traditional Mackworth Clock Test (MCT) was modified to induce decline of attended and unattended vigilance. We analyzed EEG features in different levels of attended vigilance and assessed unattended vigilance by amplitude of mismatch negative (MMN) which can be evoked by audio odd ball stimulations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226815/multi-domain-feature-selection-in-auditory-mismatch-negativity-via-parafac-based-template-matching-approach
#20
Saeed Pouryazdian, Andrew Chang, Dan J Bosnyak, Laurel J Trainor, Soosan Beheshti, Sridhar Krishnan, Saeed Pouryazdian, Andrew Chang, Dan J Bosnyak, Laurel J Trainor, Soosan Beheshti, Sridhar Krishnan, Soosan Beheshti, Dan J Bosnyak, Laurel J Trainor, Sridhar Krishnan, Saeed Pouryazdian, Andrew Chang
MisMatch Negativity (MMN) is a small event-related potential (ERP) that provide an index of sensory learning and perceptual accuracy for the cognitive research. Group-level analysis plays an important role for detecting differences at group or condition level, especially when the signal-to-noise ratio is low. Tensor factorization has provided a framework for group-level analysis of ERPs by exploiting more information of brain responses in more domains simultaneously. A 4-way ERP tensor of time × frequency × channel × subjects/condition is generated and decomposed via PARAFAC...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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