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https://www.readbyqxmd.com/read/29337239/background-suppression-and-its-relation-to-foreground-processing-of-speech-versus-non-speech-streams
#1
Xiaochen Zhang, Xiaolin Li, Jingjing Chen, Qin Gong
Since sound perception takes place against a background with a certain amount of noise, both speech and non-speech processing involve extraction of target signals and suppression of background noise. Previous works on early processing of speech phonemes largely neglected how background noise is encoded and suppressed. This study aimed to fill in this gap. We adopted an oddball paradigm where speech (vowels) or non-speech stimuli (complex tones) were presented with or without a background of amplitude-modulated noise and analyzed cortical responses related to foreground stimulus processing, including mismatch negativity (MMN), N2b, and P300, as well as neural representations of the background noise, i...
January 11, 2018: Neuroscience
https://www.readbyqxmd.com/read/29329103/analysis-of-anti-ganglioside-antibodies-by-a-line-immunoassay-in-patients-with-chronic-inflammatory-demyelinating-polyneuropathies-cidp
#2
Juliane Klehmet, Stefanie Märschenz, Klemens Ruprecht, Benjamin Wunderlich, Thomas Büttner, Rico Hiemann, Dirk Roggenbuck, Andreas Meisel
BACKGROUND: Unlike for acute immune-mediated neuropathies (IN), anti-ganglioside autoantibody (aGAAb) testing has been recommended for only a minority of chronic IN yet. Thus, we used a multiplex semi-quantitative line immunoassay (LIA) to search for aGAAb in chronic-inflammatory demyelinating polyneuropathy (CIDP) and its clinical variants. METHODS: Anti-GAAb to 11 gangliosides and sulfatide (SF) were investigated by LIA in 61 patients with IN (27 typical CIDP, 12 distal-acquired demyelinating polyneuropathy, 6 multifocal-acquired demyelinating sensory/motor polyneuropathy, 10 sensory CIDP, 1 focal CIDP and 5 multifocal-motoric neuropathy), 40 with other neuromuscular disorders (OND) (15 non-immune polyneuropathies, 25 myasthenia gravis), 29 with multiple sclerosis (MS) and 54 healthy controls (HC)...
January 12, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29305875/neural-discrimination-of-speech-sound-changes-in-a-variable-context-occurs-irrespective-of-attention-and-explicit-awareness
#3
P Virtala, E Partanen, M Tervaniemi, T Kujala
To process complex stimuli like language, our auditory system must tolerate large acoustic variance, like speaker variability, and still be sensitive enough to discriminate between phonemes and to detect complex sound relationships in, e.g., prosodic cues. Our study determined discrimination of speech sounds in input mimicking natural speech variability, and detection of deviations in regular pitch relationships (rule violations) between speech sounds. We investigated the automaticity and the influence of attention and explicit awareness on these changes by recording the neurophysiological mismatch negativity (MMN) and P3a as well as task performance from 21 adults...
January 3, 2018: Biological Psychology
https://www.readbyqxmd.com/read/29302713/psilocybin-disrupts-sensory-and-higher-order-cognitive-processing-but-not-pre-attentive-cognitive-processing-study-on-p300-and-mismatch-negativity-in-healthy-volunteers
#4
Anna Bravermanová, Michaela Viktorinová, Filip Tylš, Tomáš Novák, Renáta Androvičová, Jakub Korčák, Jiří Horáček, Marie Balíková, Inga Griškova-Bulanova, Dominika Danielová, Přemysl Vlček, Pavel Mohr, Martin Brunovský, Vlastimil Koudelka, Tomáš Páleníček
RATIONALE: Disruption of auditory event-related evoked potentials (ERPs) P300 and mismatch negativity (MMN), electrophysiological markers of attentive and pre-attentive cognitive processing, is repeatedly described in psychosis and schizophrenia. Similar findings were observed in a glutamatergic model of psychosis, but the role of serotonergic 5-HT2A receptors in information processing is less clear. OBJECTIVES: We studied ERPs in a serotonergic model of psychosis, induced by psilocybin, a psychedelic with 5-HT2A/C agonistic properties, in healthy volunteers...
January 5, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/29289720/sensory-intelligence-for-extraction-of-an-abstract-auditory-rule-a-cross-linguistic-study
#5
Xiao-Tao Guo, Xiao-Dong Wang, Xiu-Yuan Liang, Ming Wang, Lin Chen
In a complex linguistic environment, while speech sounds can greatly vary, some shared features are often invariant. These invariant features constitute so called abstract auditory rules. Our previous study has shown that with auditory sensory intelligence, the human brain can automatically extract the abstract auditory rules in the speech sound stream, presumably serving as the neural basis for speech comprehension. However, whether the sensory intelligence for extraction of abstract auditory rules in speech is inherent or experience-dependent remains unclear...
December 28, 2017: Neuroscience
https://www.readbyqxmd.com/read/29276349/mismatch-negativity-in-han-chinese-patients-with-schizophrenia-a-meta-analysis
#6
REVIEW
Yanbing Xiong, Xianbin Ll, Lei Zhao, Chuanyue Wang
Background: Previous meta-analysis revealed that mismatch negativity(MMN) amplitude decreased in patients with schizophrenia compared with healthy controls (Cohen's d, d about 1), leading to the possibility of mismatch negativity being used as a biomarker for schizophrenia. However, it is unknown whether MMN is reliably changed in Chinese patients. It is necessary to carry out a meta-analysis on MMN of Han Chinese patients with schizophrenia. Aim: To investigate whether MMN could be used as a biomarker for Han Chinese patients with schizophrenia...
October 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29248615/exploring-the-neural-correlates-of-lexical-stress-perception-in-english-among-chinese-english-bilingual-children-with-autism-spectrum-disorder-an-erp-study
#7
Juan Zhang, Yaxuan Meng, Xiuhong Tong, Zhen Yuan, Chenggang Wu
Previous studies found that individuals with autism spectrum disorder (ASD) were less sensitive to the variations of lexical stress in their native language. However, no study has been conducted to explore the perception of lexical stress in the second language among individuals with ASD. Using ERP (event-related potential) measurement with an oddball paradigm, the current study examined and compared the neural responses by Chinese-English bilingual children with ASD and typically developing controls in the processing of English lexical stress...
December 14, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29210520/supplementation-during-pregnancy-with-small-quantity-lipid-based-nutrient-supplements-or-multiple-micronutrients-compared-with-iron-and-folic-acid-increases-women-s-urinary-iodine-concentration-in-semiurban-ghana-a-randomized-controlled-trial
#8
Seth Adu-Afarwuah, Rebecca T Young, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Mamane Zeilani, Kathryn G Dewey
There is little information on whether prenatal multiple micronutrient (MMN) supplements containing iodine affect women's iodine status. In the International Lipid-based Nutrient Supplements DYAD-Ghana trial, we aimed to assess women's urinary iodine concentration (UIC, μg/L) during pregnancy, as one of the planned secondary outcomes. Women (n = 1,320) <20 weeks of gestation were randomized to consume 60 mg iron and 400 μg folic acid per day (iron and folic acid [IFA]); 18 vitamins and minerals including 250 μg iodine per day (MMN); or 20 g/day of small-quantity lipid-based nutrient supplements (LNS) with the same and additional 4 vitamins and minerals as the MMN (LNS)...
December 6, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29190522/ultrasound-and-mri-of-nerves-for-monitoring-disease-activity-and-treatment-effects-in-chronic-dysimmune-neuropathies-current-concepts-and-future-directions
#9
REVIEW
Bernhard F Décard, Mirko Pham, Alexander Grimm
New imaging modalities like high-resolution-ultrasound (HRUS) and MR-Neurography (MRN) are increasingly used for the evaluation of the peripheral nervous system. The increasing knowledge on morphological changes observed in different neuropathies has led to a better understanding of underlying pathophysiological processes. The diagnosis of acquired chronic dysimmune neuropathies (CDN) like chronic inflammatory demyelinating polyneuropathy (CIDP), Lewis-Sumner Syndrome (LSS) or multifocal motor neuropathy (MMN) can be challenging...
November 10, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29185490/aberrant-brain-response-after-auditory-deviance-in-ptsd-compared-to-trauma-controls-an-eeg-study
#10
Katrin A Bangel, Susanne van Buschbach, Dirk J A Smit, Ali Mazaheri, Miranda Olff
Part of the symptomatology of post-traumatic stress disorder (PTSD) are alterations in arousal and reactivity which could be related to a maladaptive increase in the automated sensory change detection system of the brain. In the current EEG study we investigated whether the brain's response to a simple auditory sensory change was altered in patients with PTSD relative to trauma-exposed matched controls who did not develop the disorder. Thirteen male PTSD patients and trauma-exposed controls matched for age and educational level were presented with regular auditory pure tones (1000 Hz, 200 ms duration), with 11% of the tones deviating in both duration (50 ms) and frequency (1200 Hz) while watching a silent movie...
November 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29182947/low-level-neural-auditory-discrimination-dysfunctions-in-specific-language-impairment-a-review-on-mismatch-negativity-findings
#11
REVIEW
Teija Kujala, Miika Leminen
In specific language impairment (SLI), there is a delay in the child's oral language skills when compared with nonverbal cognitive abilities. The problems typically relate to phonological and morphological processing and word learning. This article reviews studies which have used mismatch negativity (MMN) in investigating low-level neural auditory dysfunctions in this disorder. With MMN, it is possible to tap the accuracy of neural sound discrimination and sensory memory functions. These studies have found smaller response amplitudes and longer latencies for speech and non-speech sound changes in children with SLI than in typically developing children, suggesting impaired and slow auditory discrimination in SLI...
October 24, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29176886/differences-in-phonetic-discrimination-stem-from-differences-in-psychoacoustic-abilities-in-learning-the-sounds-of-a-second-language-evidence-from-erp-research
#12
Yi Lin, Ruolin Fan, Lei Mo
The scientific community has been divided as to the origin of individual differences in perceiving the sounds of a second language (L2). There are two alternative explanations: a general psychoacoustic origin vs. a speech-specific one. A previous study showed that such individual variability is linked to the perceivers' speech-specific capabilities, rather than the perceivers' psychoacoustic abilities. However, we assume that the selection of participants and parameters of sound stimuli might not appropriate...
2017: PloS One
https://www.readbyqxmd.com/read/29172074/using-rotated-speech-to-approximate-the-acoustic-mismatch-negativity-response-to-speech
#13
Ellen Marklund, Francisco Lacerda, Iris-Corinna Schwarz
The mismatch negativity (MMN) response is influenced by the magnitude of the acoustic difference between standard and deviant, and the response is typically larger to linguistically relevant changes than to linguistically irrelevant changes. Linguistically relevant changes between standard and deviant typically co-occur with differences between the two acoustic signals. It is therefore not straightforward to determine the contribution of each of those two factors to the MMN response. This study investigated whether spectrally rotated speech can be used to determine the impact of the acoustic difference on the MMN response to a combined linguistic and acoustic change between standard and deviant...
November 21, 2017: Brain and Language
https://www.readbyqxmd.com/read/29164571/assessment-of-mismatch-negativity-and-p300-response-in-patients-with-disorders-of-consciousness
#14
X-Y Wang, H-Y Wu, H-T Lu, T-T Huang, H Zhang, T Zhang
OBJECTIVE: To evaluate changes in mismatch negativity (MMN) and P300 response in vegetative state (VS) and minimally conscious state (MCS) patients before and after treatment, and their value for prediction of prognosis. PATIENTS AND METHODS: Event-related potentials (ERPs), performed on 11 patients classified as VS (n = 6) or MCS (n = 5), and five healthy participants (i.e., control group). We performed a six months telephone follow-up to monitor changes in consciousness recovery...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29151101/psychoacoustics-and-neurophysiological-alterations-after-30-36-hours-of-sleep-deprivation
#15
Adrián Poblano, Sergio Díaz-Leines, Olga Gama-Moreno, Blanca Flores-Avalos
BACKGROUND AND AIM: Sleep deprivation (SD) may result in perceptual and cognitive alterations in healthy subjects. Our objective was to compare whether psychoacoustics and neurophysiological variables in healthy subjects were altered after SD of 30-36 h. METHOD: We examined 22 subjects by means of several psychoacoustics tests, P300 and mismatch negativity (MMN) recordings, and brainstem auditory evoked potentials (BAEP) before and after 30-36 h of SD. RESULTS: In the psychoacoustics tests, we found that after SD, difficulties were experienced by the left ear in the discrimination of words in noise and by the right ear in music discrimination...
November 18, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29138621/influence-of-the-culture-media-and-the-organic-matter-in-the-growth-of-paxillus-ammoniavirescens-contu-dessi
#16
Elena Fernández-Miranda Cagigal, Abelardo Casares Sánchez
The genus Paxillus is characterized by the difficulty of species identification, which results in reproducibility problems, as well as the need for large quantities of fungal inoculum. In particular, studies of Paxillus ammoniavirescens have reported divergent results in the in vitro growth while little is known of its capacity to degrade organic matter. For all the above, and assuming that this variability could be due to an inappropriate culture media, the aim of this study was to analyse growth in different culture media (MMN, MS, and 1/2 MS) and in the case of MMN in presence/absence of two types of organic matter (fresh litter and senescence litter) to probe the saprophytic ability of P...
September 2017: Mycobiology
https://www.readbyqxmd.com/read/29136715/-analysis-of-the-clinical-and-electrophysiological-characteristics-of-multifocal-motor-neuropathy
#17
H F Wang, F Yang, F Cui, Z H Chen, L Ling, X S Huang
Ten patients diagnosed with multifocal motor neuropathy (MMN) were recruited in the Department of Neurology at Chinese PLA General Hospital from January 1, 2009 to August 31, 2015. The clinical and electrophysiological features were analyzed retrospectively. All patients complained of progressive asymmetric limb weakness, which was more severe in distal than in proximal. Five presented muscle atrophy. None had sensory disturbances. All suffered diminished or disappeared tendon reflex, whereas Babinski signs were negative...
November 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29126047/clinico-sonographical-evaluation-of-idiopathic-clubfoot-and-its-correction-by-ponseti-method-a-prospective-study
#18
Sumit Chawla, Mallika Gupta, Varun Pandey, Abhishek Jain, Manoj Kumar
BACKGROUND: Objective evaluation of infant with clubfoot is required as conventional imaging modality is of limited usefulness. Ultrasound shows to be a promising technique for assessing deformity and monitoring of clubfoot correction. AIM: Study was done to evaluate the deformity sonographically; to assess the changes in these parameters after treatment by Ponseti method and to correlate these ultrasonographic variables with clinical Pirani score. MATERIALS AND METHODS: 82 feet in 54 children were observed...
December 2017: Foot
https://www.readbyqxmd.com/read/29119657/reduced-neural-responses-to-vocal-fear-a-potential-biomarker-for-callous-uncaring-traits-in-early-childhood
#19
Caroline P Hoyniak, John E Bates, Isaac T Petersen, Chung-Lin Yang, Isabelle Darcy, Nathalie M G Fontaine
OBJECTIVE: Callous-unemotional (CU) traits are characterized by a lack of guilt and empathy, and low responsiveness to distress and fear in others. Children with CU traits are at-risk for engaging in early and persistent conduct problems. Individuals showing CU traits have been shown to have reduced neural responses to others' distress (e.g., fear). However, the neural components of distress responses in children with CU traits have not been investigated in early childhood. In the current study, we examined neural responses that underlie the processing of emotionally valenced vocal stimuli using the event-related potential technique in a group of preschoolers...
November 8, 2017: Developmental Science
https://www.readbyqxmd.com/read/29102707/neurophysiological-differentiation-between-preattentive-and-attentive-processing-of-emotional-expressions-on-french-vowels
#20
Mathilde Carminati, Nicole Fiori-Duharcourt, Frédéric Isel
The present electrophysiological study investigated the processing of emotional prosody by minimizing as much as possible the effect of emotional information conveyed by the lexical-semantic context. Emotionally colored French vowels (i.e., happiness, sadness, fear, and neutral) were presented in a mismatch negativity (MMN) oddball paradigm. Both the MMN, i.e., an event-related potential (ERP) component thought to reflect preattentive change detection, and the P3a, i.e., an ERP marker of involuntary orientation of attention toward deviant stimuli, were significantly modulated by the emotional deviants compared to the neutral ones...
November 2, 2017: Biological Psychology
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