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https://www.readbyqxmd.com/read/29792081/efficacy-of-a-word-and-text-based-intervention-for-students-with-significant-reading-difficulties
#1
Sharon Vaughn, Garrett J Roberts, Jeremy Miciak, Pat Taylor, Jack M Fletcher
We examine the efficacy of an intervention to improve word reading and reading comprehension in fourth- and fifth-grade students with significant reading problems. Using a randomized control trial design, we compare the fourth- and fifth-grade reading outcomes of students with severe reading difficulties who were provided a researcher-developed treatment with reading outcomes of students in a business-as-usual (BAU) comparison condition. A total of 280 fourth- and fifth-grade students were randomly assigned within school in a 1:1 ratio to either the BAU comparison condition ( n = 139) or the treatment condition ( n = 141)...
May 1, 2018: Journal of Learning Disabilities
https://www.readbyqxmd.com/read/29787803/quality-of-life-and-functional-assessment-of-facial-palsy-patients-a-questionnaire-study
#2
Eva Györi, Christopher Przestrzelski, Igor Pona, Michael Hagmann, Thomas Rath, Christine Radtke, Chieh-Han John Tzou
BACKGROUND: Facial palsy leads to functional and aesthetic deficits, which impair the quality of life of affected patients. General health-related and disease-specific questionnaires are available for quality of life assessment. In this study, observer-based analysis of facial function (Sunnybrook Facial Grading Scale) was compared patient-based to facial palsy-specific gradings (Facial Clinimetric Evaluation Scale and Facial Disability Index), and general health-related quality of life questionnaires (SF-36)...
May 19, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29787739/apathy-in-individuals-with-parkinson-s-disease-associated-with-mild-cognitive-impairment-a-neuropsychological-investigation
#3
Alberto Costa, Antonella Peppe, Silvia Zabberoni, Francesco Scalici, Carlo Caltagirone, Giovanni Augusto Carlesimo
Apathy is frequently reported in individuals with Parkinson's disease (PD) and is hypothesized to be associated with frontal-striatal related cognitive functions. Available data, however, do not provide univocal results. Moreover, this relationship has been poorly investigated in PD patients with mild cognitive impairment (MCI). This study was aimed at investigating the association between severity of apathy of PD patients and their performance on neuropsychological tests investigating executive abilities. Individuals with PD (i...
May 19, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29785584/interferon-free-therapy-in-hepatitis-c-virus-hcv-monoinfected-and-hcv-hiv-coinfected-patients-effect-on-cognitive-function-fatigue-and-mental-health
#4
Felix Kleefeld, Sophie Heller, Patrick Ingiliz, Heiko Jessen, Anders Petersen, Ute Kopp, Antje Kraft, Katrin Hahn
The efficacy and safety of interferon-free therapies for hepatitis C virus (HCV) infection have been reported. Considering the accumulating evidence for a direct central nervous system infection by HCV, we aim to evaluate the effect of direct acting antivirals (DAA) therapy on cognitive function in HCV patients. We conducted a longitudinal analysis of the cognitive performance of 22 patients (8 HCV+, 14 HCV+/HIV+) who completed neuropsychological testing at baseline and at week 12 after DAA therapy. In 20 patients, we analyzed specific attention parameters derived from an experimental testing based on the Theory of Visual Attention (TVA)...
May 21, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29784345/development-of-dried-serum-spot-sampling-techniques-for-the-assessment-of-trace-elements-in-serum-samples-by-la-icp-ms
#5
María Pilar Chantada-Vázquez, Jorge Moreda-Piñeiro, Alicia Cantarero-Roldán, Pilar Bermejo-Barrera, Antonio Moreda-Piñeiro
A novel approach for serum analysis by dried matrix spot (DMS) technique is proposed. The methodology consists of sampling filter paper discs (2.7 mm in diameter) containing the large amount of serum retained after a single spotting. Several oxidizers (sodium chlorate, sodium azide, acetic acid, formic acid, 1-butyl-3-methylimidazoliumm chloride/bromide) were tested (oxidizers premixed with the sample before spotting, and papers previously soaked in concentrated additive/oxidizer solutions). Direct multi-element determination (Al, Be, Ca, Cu, Fe, K, Li, Mg, Mn, Mo, Na, P, Rb, Se, V, and Zn) in dried serum spots at very low levels was therefore assessed by laser ablation (LA) coupled with inductively coupled plasma - mass spectrometry (ICP-MS)...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784047/memory-related-subjective-cognitive-symptoms-in-the-adult-population-prevalence-and-associated-factors-results-of-the-life-adult-study
#6
Tobias Luck, Susanne Roehr, Francisca S Rodriguez, Matthias L Schroeter, A Veronica Witte, Andreas Hinz, Anja Mehnert, Christoph Engel, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G Riedel-Heller
BACKGROUND: Subjectively perceived memory problems (memory-related Subjective Cognitive Symptoms/SCS) can be an indicator of a pre-prodromal or prodromal stage of a neurodegenerative disease such as Alzheimer's disease. We therefore sought to provide detailed empirical information on memory-related SCS in the dementia-free adult population including information on prevalence rates, associated factors and others. METHODS: We studied 8834 participants (40-79 years) of the population-based LIFE-Adult-Study...
May 21, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29783125/contralateral-functional-reorganization-of-the-speech-supplementary-motor-area-following-neurosurgical-tumor-resection
#7
Srinivas Chivukula, Brian K Pikul, Keith L Black, Nader Pouratian, Susan Y Bookheimer
We evaluated plasticity in speech supplemental motor area (SMA) tissue in two patients using functional magnetic resonance imaging (fMRI), following resection of tumors in or associated with the dominant hemisphere speech SMA. Patient A underwent resection of a anaplastic astrocytoma NOS associated with the left speech SMA, experienced SMA syndrome related mutism postoperatively, but experienced full recovery 14 months later. FMRI performed 32 months after surgery demonstrated a migration of speech SMA to homologous contralateral hemispheric regional tissue...
May 18, 2018: Brain and Language
https://www.readbyqxmd.com/read/29782329/longitudinal-fmri-study-of-language-recovery-after-a-left-hemispheric-ischemic-stroke
#8
Rodolphe Nenert, Jane B Allendorfer, Amber M Martin, Christi Banks, Jennifer Vannest, Scott K Holland, Kimberly W Hart, Christopher J Lindsell, Jerzy P Szaflarski
BACKGROUND: Recovery from stroke-induced aphasia is typically protracted and involves complex functional reorganization. The relative contributions of the lesioned and non-lesioned hemispheres to this process have been examined in several cross-sectional studies but longitudinal studies involving several time-points and large numbers of subjects are scarce. OBJECTIVE: The aim of this study was to address the gaps in the literature by longitudinally studying the evolution of post-stroke lateralization and localization of language-related fMRI activation in the first year after single left hemispheric ischemic stroke...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29781879/cognitive-burden-of-common-non-antiretroviral-medications-in-hiv-infected-women
#9
Leah H Rubin, Kendra K Radtke, Seenae Eum, Bani Tamraz, Krithika N Kumanan, Gayle Springer, Pauline M Maki, Kathryn Anastos, Daniel Merenstein, Roksana Karim, Kathleen M Weber, Deborah Gustafson, Ruth M Greenblatt, Jeffrey R Bishop
OBJECTIVE: The aging HIV population has increased comorbidity burden and consequently non-antiretroviral (ARV) medication utilization. Many non-ARV medications have known neurocognitive-adverse effects ("NC-AE medications"). We assessed the cognitive effects of NC-AE medications in HIV+ and HIV- women. METHODS: 1558 participants (1037 HIV+; mean age 46) from the Women's Interagency HIV Study completed a neuropsychological test battery between 2009 and 2011...
May 16, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29781396/age-related-differences-in-idea-generation-and-selection-for-propositional-language
#10
Daniel L Madden, Martin V Sale, Gail A Robinson
Conceptual preparation mechanisms such as novel idea generation and selection from amongst competing alternatives are critical for language production and may contribute to age-related language deficits. This study investigated whether older adults show diminished idea generation and selection abilities, compared to younger adults. Twenty younger (18-35 years) and 20 older (60-80 years) adults completed two novel experimental tasks, an idea generation task and a selection task. Older participants were slower than younger participants overall on both tasks...
May 21, 2018: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/29781345/sluggish-cognitive-tempo-predicts-academic-fluency-beyond-contributions-of-core-academic-skills-attention-and-motor-speed
#11
Lisa A Jacobson, E Mark Mahone
OBJECTIVE: Sluggish Cognitive Tempo (SCT) is a distinct behavioral phenotype characterized by such symptoms as being slow to complete tasks, appearing drowsy or sleepy, and lacking initiative. Subcomponents of SCT appear differentially associated with inattention symptoms and child outcomes. Much of the work in this area has examined associations between SCT symptoms and ratings of behavior; few studies have examined associations with child performance. METHOD: We examined associations between SCT and timed reading and math skills in 247 referred youth ( M age = 11...
May 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29777733/food-allergy-guidance-in-the-united-states-military-a-work-group-report-from-the-aaaai-military-allergy-and-immunology-assembly-maia
#12
Kirk Waibel, Rachel Lee, Christopher Coop, Yun Mendoza, Kevin White
A diagnosis of food allergy adversely impacts one's ability to join or remain in the military. Inadequate knowledge or misconceptions of current military-specific standards regarding food allergy and how these apply to enlistment, induction, and retention in the United States military can potentially lead to inaccurate counseling as each military service has specific regulations which impact the evaluation and decision-making process. Recognizing this knowledge gap, the American Allergy, Asthma, and Immunology (AAAAI) Military Allergy and Immunology Assembly (MAIA) established a Work Group who reviewed and summarized all aspects of military instructions, policies, and regulations regarding IgE mediated food allergy...
May 16, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29766459/cognitive-functioning-in-chiari-malformation-type-i-without-posterior-fossa-surgery
#13
Maitane García, Esther Lázaro, Juan Francisco López-Paz, Oscar Martínez, Manuel Pérez, Sarah Berrocoso, Mohammad Al-Rashaida, Imanol Amayra
Chiari Malformation type I (CM-I) is a neurological disorder characterized by a displacement of the cerebellar tonsils through the foramen magnum into the spinal canal. Most research has focused on physical symptomatology but few studies include neuropsychological examinations. Moreover, although current research highlights the involvement of the cerebellum on higher cognitive functions, little is known about cognitive consequences associated with CM-I. The aim of this study is to analyze cognitive functioning between 39 CM-I patients and 39 healthy controls, matched by gender, age and years of education...
May 15, 2018: Cerebellum
https://www.readbyqxmd.com/read/29764295/acoustic-sources-of-accent-in-second-language-japanese-speech
#14
Kaori Idemaru, Peipei Wei, Lucy Gubbins
This study reports an exploratory analysis of the acoustic characteristics of second language (L2) speech which give rise to the perception of a foreign accent. Japanese speech samples were collected from American English and Mandarin Chinese speakers ( n = 16 in each group) studying Japanese. The L2 participants and native speakers ( n = 10) provided speech samples modeling after six short sentences. Segmental (vowels and stops) and prosodic features (rhythm, tone, and fluency) were examined. Native Japanese listeners ( n = 10) rated the samples with regard to degrees of foreign accent...
May 1, 2018: Language and Speech
https://www.readbyqxmd.com/read/29764201/cognitive-predictors-of-sequential-motor-impairments-in-children-with-dyslexia-and-or-attention-deficit-hyperactivity-disorder
#15
Marie-Ève Marchand-Krynski, Anne-Marie Bélanger, Olivier Morin-Moncet, Miriam H Beauchamp, Gabriel Leonard
This study examined cognitive predictors of sequential motor skills in 215 children with dyslexia and/or attention deficit/hyperactivity disorder (ADHD). Visual working memory and math fluency abilities contributed significantly to performance of sequential motor abilities in children with dyslexia (N = 67), ADHD (N = 66) and those with a comorbid diagnosis (N = 82), generally without differentiation between groups. In addition, primary diagnostic features of each disorder, such as reading and inattention, did not contribute to the variance in motor skill performance of these children...
May 15, 2018: Developmental Neuropsychology
https://www.readbyqxmd.com/read/29763451/episodic-memory-and-delayed-recall-are-significantly-more-impaired-in-younger-patients-with-deficit-schizophrenia-than-in-elderly-patients-with-amnestic-mild-cognitive-impairment
#16
Buranee Kanchanatawan, Sookjaroen Tangwongchai, Thitiporn Supasitthumrong, Sira Sriswasdi, Michael Maes
BACKGROUND: Both amnestic mild cognitive impairment (aMCI) and schizophrenia, in particular deficit schizophrenia, are accompanied by cognitive impairments. The aim of the present study was to examine the cognitive differences between aMCI and (non)deficit schizophrenia. METHODS: Towards this end we recruited 60 participants with aMCI, 40 with deficit and 40 with nondeficit schizophrenia and 103 normal volunteers. Cognitive measures were assessed with the Consortium to Establish a Registry for Alzheimer's disease (CERAD) using the Verbal Fluency Test (VFT), Boston Naming Test (BNT), Mini-Mental State Examination (MMSE), Word list memory (WLM), Word list recall (WLRecall) and Word list recognition (WLRecognition)...
2018: PloS One
https://www.readbyqxmd.com/read/29756356/neuroimaging-abnormalities-in-individuals-exhibiting-parkinson-s-disease-risk-markers
#17
Marcus Heldmann, Janna Heeren, Christine Klein, Linus Rauch, Johann Hagenah, Thomas F Münte, Meike Kasten, Norbert Brüggemann
BACKGROUND: The concept of prodromal Parkinson's disease (PD) involves variable combinations of nonmotor features and subtle motor abnormalities as a result of ongoing neurodegeneration in the brain stem including substantia nigra (SN) and abnormal findings upon transcranial sonography and nuclear imaging. Except for nuclear imaging, the predictive value of risk markers for the conversion to overt PD is low. OBJECTIVE: The objective of this study was to determine whether PD risk markers are associated with changes in brain structure and to what extent cognitive changes are risk markers for PD...
May 14, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29754132/recovery-of-brain-abscess-induced-stuttering-after-neurosurgical-intervention
#18
Daisuke Sudo, Youichi Doutake, Hidenori Yokota, Eiju Watanabe
Stuttering occurs in approximately 5% of all children and 1% of adults. One type, neurogenic stuttering, is usually attributable to strokes or other structural damages to the brain areas that are responsible for language fluency. Here, we present the first case of neurogenic stuttering caused by a brain abscess. The patient was a 60-year-old man admitted for a seizure and administered an anticonvulsant, after which he began stuttering. MRI revealed a brain abscess in the left frontal lobe that extended to the dorsolateral prefrontal cortex (BA (Brodmann's area) 9 and 46), frontal eye field (BA 8) and premotor cortex and supplementary motor area (BA 6)...
May 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29754106/the-effect-of-transcranial-direct-current-stimulation-on-psychotic-symptoms-of-schizophrenia-is-associated-with-oxy-hemoglobin-concentrations-in-the-brain-as-measured-by-near-infrared-spectroscopy-a-pilot-study
#19
Zui Narita, Takamasa Noda, Shiori Setoyama, Kazuki Sueyoshi, Takuma Inagawa, Tomiki Sumiyoshi
Transcranial direct current stimulation (tDCS) has been shown to be effective in treating some of the symptoms of schizophrenia. In the current study, we sought to determine whether oxy-hemoglobin ([oxy-Hb]), measured by near-infrared spectroscopy (NIRS), is associated with effects of transcranial direct current stimulation (tDCS) on psychotic symptoms of schizophrenia. Twenty-six patients underwent tDCS (2 mA × 20 min) two times per day for five consecutive days. The anodal electrode was placed over the left dorsolateral prefrontal cortex while the cathodal electrode was placed over the right supraorbital region...
May 8, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29753908/individual-differences-in-children-s-pronoun-processing-during-reading-detection-of-incongruence-is-associated-with-higher-reading-fluency-and-more-regressions
#20
Sarah Eilers, Simon P Tiffin-Richards, Sascha Schroeder
In two eye tracking experiments, we tested fourth graders' and adults' sensitivity to gender feature mismatches during reading of pronouns and their susceptibility to interference of feature-matching entities in the sentence. In Experiment 1, we showed children and adults two-phrase sentences such as "Leon{m}/Lisa{f} shooed away the sparrow{m}/the seagull{f} and then he{m} ate the tasty sandwich." Eye tracking measures showed no qualitative differences between children's and adults' processing of the pronouns...
May 10, 2018: Journal of Experimental Child Psychology
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