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https://www.readbyqxmd.com/read/28818760/slow-gait-speed-is-associated-with-executive-function-decline-in-older-people-with-mild-to-moderate-dementia-a-one-year-longitudinal-study
#1
Morag E Taylor, Danielle A Lasschuit, Stephen R Lord, Kim Delbaere, Susan E Kurrle, A Stefanie Mikolaizak, Tasha Kvelde, Jacqueline C T Close
OBJECTIVES: This study aimed to document change in neuropsychological, physical and functional performance over one year and to investigate the relationship between baseline gait speed and cognitive decline in this period in older people with dementia. METHODS: One hundred and seventy-seven older people with dementia (Mini-Mental State Examination 11-23; Addenbrooke's Cognitive Examination-Revised <83) residing in the community or low level care facility completed baseline neuropsychological, physical and functional assessments...
July 31, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28818624/white-matter-microstructure-integrity-in-relation-to-reading-proficiency%C3%A2
#2
C Nikki Arrington, Paulina A Kulesz, Jenifer Juranek, Paul T Cirino, Jack M Fletcher
Components of reading proficiency such asaccuracy, fluency, and comprehension require the successful coordination of numerous, yet distinct, cortical regions. Underlying white matter tracts allow for communication among these regions. This study utilized unique residualized tract - based spatial statistics methodology to identify the relations of white matter microstructure integrity to three components of reading proficiency in 49 school - aged children with typically developing phonological decoding skills and 27 readers with poor decoders...
August 14, 2017: Brain and Language
https://www.readbyqxmd.com/read/28816636/the-distress-thermometer-predicts-subjective-but-not-objective-cognitive-complaints-six-months-after-treatment-initiation-in-cancer-patients-receiving-a-curative-cancer-treatment
#3
Michelle Lycke, Tessa Lefebvre, Lies Pottel, Hans Pottel, Lore Ketelaars, Karin Stellamans, Koen Van Eygen, Philippe Vergauwe, Patrick Werbrouck, Laurence Goethals, Patricia Schofield, Tom Boterberg, Philip R Debruyne
OBJECTIVES: Research has indicated that cancer-related cognitive impairments (CRCI) may be influenced by psychosocial factors such as distress, worry and fatigue. Therefore, we aimed to validate the distress thermometer (DT) as a screening tool to detect CRCI six months post treatment initiation in a group of general cancer patients. METHODS: Patients(18 years, n 125) with a histologically confirmed diagnosis of a solid cancer or haematological malignancy, scheduled for a curative treatment, were evaluated at baseline (T0) and six months post-treatment initiation (T1) for CRCI by a neuropsychological assessment including patient-reported outcome measures (PROMs)...
August 17, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28815390/abnormal-relationships-between-local-and-global-brain-measures-in-subjects-at-clinical-high-risk-for-psychosis-a-pilot-study
#4
Jun Konishi, Elisabetta C Del Re, Sylvain Bouix, Gabriëlla A M Blokland, Raquelle Mesholam-Gately, Kristen Woodberry, Margaret Niznikiewicz, Jill Goldstein, Yoshio Hirayasu, Tracey L Petryshen, Larry J Seidman, Martha E Shenton, Robert W McCarley
We examined whether abnormal volumes of several brain regions as well as their mutual associations that have been observed in patients with schizophrenia, are also present in individuals at clinical high-risk (CHR) for developing psychosis. 3T magnetic resonance imaging was acquired in 19 CHR and 20 age- and handedness-matched controls. Volumes were measured for the body and temporal horns of the lateral ventricles, hippocampus and amygdala as well as total brain, cortical gray matter, white matter, and subcortical gray matter volumes...
August 16, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28815262/semantic-and-phonological-encoding-in-adults-who-stutter-silent-responses-to-pictorial-stimuli
#5
Irena Vincent
Purpose: Research on language planning in adult stuttering is relatively sparse and offers diverging arguments about a potential causative relationship between semantic and phonological encoding and fluency breakdowns. This study further investigated semantic and phonological encoding efficiency in adults who stutter (AWS) by means of silent category and phoneme identification, respectively. Method: Fifteen AWS and 15 age- and sex-matched adults who do not stutter (ANS) participated...
August 16, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28815180/assessing-cognitive-estimation-and-its-effects-on-community-integration-in-people-with-acquired-brain-injury-undergoing-rehabilitation
#6
Dónal G Fortune, Helen L Richards
The purpose of the present study was to examine the convergent and divergent validity of the Biber Cognitive Estimation Test (BCET) in individuals with ABI undergoing postacute rehabilitation and to assess the measure's ability to account for unique variance in community integration following rehabilitation. Participants with ABI referred for postacute rehabilitation (N = 201) were assessed on the BCET and a number of other neuropsychological tests that have been demonstrated to rely on aspects of executive processing (Trail-Making Test, Modified Six Elements Test, and verbal fluency measures) and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28814979/executive-functioning-in-cornelia-de-lange-syndrome-domain-asynchrony-and-age-related-performance
#7
Donna Reid, Jo Moss, Lisa Nelson, Laura Groves, Chris Oliver
BACKGROUND: The aim of this study was to examine executive functioning in adolescents and adults with Cornelia de Lange syndrome (CdLS) to identify a syndrome and age-related profile of cognitive impairment. METHODS: Participants were 24 individuals with CdLS aged 13-42 years (M = 22; SD = 8.98), and a comparable contrast group of 21 individuals with Down syndrome (DS) aged 15-33 years (M = 24; SD = 5.82). Measures were selected to test verbal and visual fluency, inhibition, perseverance/flexibility, and working memory and comprised both questionnaire and performance tests...
2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28810593/carotid-atherosclerosis-promotes-the-progression-of-alzheimer-s-disease-a-three-year-prospective-study
#8
Jing Xiang
Although cerebrovascular diseases have been considered as risk factors for cognitive decline and dementia, the associations between atherosclerosis and Alzheimer's disease (AD) have not been fully examined and remain controversial. The aim of this three-year prospective study was to investigate whether arotid artery atherosclerosis accelerates cognitive impairment in AD patients. The association of carotid intimal medial thickness (IMT) with prospective trajectories of cognitive function was assessed among 521 patients with light to moderate AD, and 437 AD patients were followed up annually for 3 years...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810135/is-processing-of-symbols-and-words-influenced-by-writing-system-evidence-from-chinese-korean-english-and-greek
#9
Angeliki Altani, George K Georgiou, Ciping Deng, Jeung-Ryeul Cho, Katerina Katopodi, Wei Wei, Athanassios Protopapas
We examined cross-linguistic effects in the relationship between serial and discrete versions of digit naming and word reading. In total, 113 Mandarin-speaking Chinese children, 100 Korean children, 112 English-speaking Canadian children, and 108 Greek children in Grade 3 were administered tasks of serial and discrete naming of words and digits. Interrelations among tasks indicated that the link between rapid naming and reading is largely determined by the format of the tasks across orthographies. Multigroup path analyses with discrete and serial word reading as dependent variables revealed commonalities as well as significant differences between writing systems...
August 12, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28810134/improvements-in-reading-accuracy-as-a-result-of-increased-interletter-spacing-are-not-specific-to-children-with-dyslexia
#10
Britt Hakvoort, Madelon van den Boer, Tineke Leenaars, Petra Bos, Jurgen Tijms
Recently, increased interletter spacing (LS) has been studied as a way to enhance reading fluency. It is suggested that increased LS improves reading performance, especially in poor readers. Theoretically, these findings are well substantiated as a result of diminished crowding effects. Empirically, however, findings on LS are inconclusive. In two experiments, we examined whether effects of increased LS are specific to children with dyslexia and whether increased LS affects word or sentence processing. In the first experiment, 30 children with dyslexia and 30 controls (mean age=9years 11months) read sentences in standard and increased LS conditions...
August 12, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28807493/homocysteine-and-cognitive-function-in-parkinson-s-disease
#11
Nicole Licking, Charles Murchison, Brenna Cholerton, Cyrus P Zabetian, Shu-Ching Hu, Thomas J Montine, Amie L Peterson-Hiller, Kathryn A Chung, Karen Edwards, James B Leverenz, Joseph F Quinn
INTRODUCTION: Increased plasma homocysteine (HC) is a risk factor for dementia in the general population. Levodopa therapy causes increased plasma HC, but it remains unclear whether elevated plasma HC is associated with cognitive impairment in Parkinson's disease (PD). METHODS: The study population includes all participants in the Pacific Northwest Udall Center (PANUC) Clinical cohort at the time of the study, consisting of 294 individuals with PD who had a standardized neuropsychological assessment and plasma collection for HC measurement...
August 9, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28806899/executive-functioning-in-cornelia-de-lange-syndrome-domain-asynchrony-and-age-related-performance
#12
Donna Reid, Jo Moss, Lisa Nelson, Laura Groves, Chris Oliver
BACKGROUND: The aim of this study was to examine executive functioning in adolescents and adults with Cornelia de Lange syndrome (CdLS) to identify a syndrome and age-related profile of cognitive impairment. METHODS: Participants were 24 individuals with CdLS aged 13-42 years (M = 22; SD = 8.98), and a comparable contrast group of 21 individuals with Down syndrome (DS) aged 15-33 years (M = 24; SD = 5.82). Measures were selected to test verbal and visual fluency, inhibition, perseverance/flexibility, and working memory and comprised both questionnaire and performance tests...
August 15, 2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28805755/-an-analysis-of-postoperative-cognitive-dysfunction-in-different-methods-of-coronary-artery-bypass
#13
G Yu Alekseevich, M V Rodikov, A V Marchenko, P A Myalyuk, G V Alekseevich
AIM: To evaluate changes in cognitive functions in patients with coronary heart disease before and after coronary artery bypass grafting (CABG) in a planned manner. MATERIAL AND METHODS: The study included 192 patients divided into 3 groups: in group 1 patients (n=88) underwent standard CABG; in group 2 (n=61) different methods of CABG were used; a control group consisted of 43 people. MMSE, FAB, Clock drawing test, Shultz tables, semantic verbal fluency, Wechsler adult intelligence scale were used for neurological testing...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28802988/does-education-play-a-role-in-language-reorganization-after-surgery-in-drug-refractory-temporal-lobe-epilepsy-an-fmri-based-study
#14
Kapil Chaudhary, Bhargavi Ramanujam, S Senthil Kumaran, P Sarat Chandra, Ashima Nehra Wadhawan, Ajay Garg, Manjari Tripathi
OBJECTIVES: Patients with drug refractory epilepsy (DRE) and a high level of education may differ in their language recovery after surgery. Our aim was to determine whether there were differences in the extent of improvement and pattern of reorganization of language functions on functional magnetic resonance imaging (fMRI) after surgery to treat refractory temporal lobe epilepsy (TLE) between patients with more than 12 years of formal education versus those with a shorter period of regular schooling...
July 29, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28802628/physical-activity-domains-and-cognitive-function-over-three-years-in-older-adults-with-subjective-memory-complaints-secondary-analysis-from-the-mapt-trial
#15
Philipe de Souto Barreto, Sandrine Andrieu, Yves Rolland, Bruno Vellas
OBJECTIVES: We aimed to examine the associations of physical activity (PA) domains (i.e., PA in leisure-time (LTPA), for housework (HPA), or for gardening (GPA)) with cognitive function in older adults with subjective memory complaints (no-dementia) and to investigate if those associations were dependent on the status of apolipoprotein E allele 4 (APOE4), omega-3 levels and mild cognitive impairment (MCI). DESIGN: Observational prospective secondary analysis using longitudinal data from a randomized controlled trial...
July 26, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28801008/the-course-of-quality-of-life-and-neurocognition-in-newly-diagnosed-patients-with-glioblastoma
#16
B Flechl, C Sax, M Ackerl, R Crevenna, A Woehrer, J Hainfellner, M Preusser, G Widhalm, B Kiesel, C Lütgendorf-Caucig, K Dieckmann, C Steffal, C Marosi, M R Hassler
BACKGROUND: The importance of QoL and neurocognitive functions in patients with glioblastoma (GB) is above controversy by now. We followed newly diagnosed GB patients treated with radio-chemotherapy during their course of disease by continuously evaluating their quality of life (QoL) and cognitive functions. METHODS: We included consecutive patients with newly diagnosed GB from 2010 to 2013 at the Medical University of Vienna. To assess QoL the EORTC QLQ C30 and BN20 questionnaire were used...
August 8, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28800632/radar-a-novel-fast-screening-method-for-reading-difficulties-with-special-focus-on-dyslexia
#17
Ioannis Smyrnakis, Vassilios Andreadakis, Vassilios Selimis, Michail Kalaitzakis, Theodora Bachourou, Georgios Kaloutsakis, George D Kymionis, Stelios Smirnakis, Ioannis M Aslanides
Dyslexia is a developmental learning disorder of single word reading accuracy and/or fluency, with compelling research directed towards understanding the contributions of the visual system. While dyslexia is not an oculomotor disease, readers with dyslexia have shown different eye movements than typically developing students during text reading. Readers with dyslexia exhibit longer and more frequent fixations, shorter saccade lengths, more backward refixations than typical readers. Furthermore, readers with dyslexia are known to have difficulty in reading long words, lower skipping rate of short words, and high gaze duration on many words...
2017: PloS One
https://www.readbyqxmd.com/read/28800514/the-relationship-between-executive-functions-and-fluid-intelligence-in-euthymic-bipolar-disorder-patients
#18
Belén Goitia, Facundo Manes, Teresa Torralva, Mariano Sigman, John Duncan, Marcelo Cetkovich, María Roca
Distinct cognitive deficits have been described in Bipolar disorder (BD), including executive impairments, commonly attributed to frontal dysfunction. However, recent attention has been paid to the heterogeneity of cognitive functioning in this population, suggesting that the executive deficits observed in BD might be due to a loss in fluid intelligence (g). Following our previous line of investigation in multiple neurological and psychiatric conditions we aimed at determining the role of g in frontal deficits in BD...
August 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28800328/effects-of-exercise-on-cognitive-function-in-older-people-with-dementia-a-randomized-controlled-trial
#19
Annika Toots, Håkan Littbrand, Gustaf Boström, Carl Hörnsten, Henrik Holmberg, Lillemor Lundin-Olsson, Nina Lindelöf, Peter Nordström, Yngve Gustafson, Erik Rosendahl
BACKGROUND: Although physical exercise has been suggested to influence cognitive function, previous exercise studies show inconsistent results in people with dementia. OBJECTIVES: To investigate effects of exercise on cognitive function in people with dementia. METHOD: The Umeå Dementia and Exercise (UMDEX) study, a cluster-randomized controlled trial, was set in 16 nursing homes in Umeå, Sweden. One hundred-and-forty-one women and 45 men with dementia; mean age of 85 y and mean Mini-Mental State Examination (MMSE) score of 15, were randomized to a High-Intensity Functional Exercise program or a seated attention control activity...
August 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28797828/gene-expression-profiling-of-fima-gene-encoding-fimbriae-among-clinical-isolates-of-porphyromonas-gingivalis-in-response-to-photo-activated-disinfection-therapy
#20
Maryam Pourhajibagher, Abbas Bahador
BACKGROUND: The endodontic infection therapy majorly aims to eradicate the microbial pathogens. Photo-activated disinfection (PAD), also known as antimicrobial photodynamic therapy, is an alternative antimicrobial modality used to control the microorganisms causing endodontic infections. Notably, microorganisms may be exposed to sub-lethal doses of PAD (sPAD), influencing microbial virulence. The present study assessed the effects of sPAD on expression profiling of the gene associated with the biofilm formation being the most essential virulence factor in Porphyromonas gingivalis strain cells that survive the photodynamic reatment in vivo...
August 7, 2017: Photodiagnosis and Photodynamic Therapy
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