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functional mitral regurgitation

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https://www.readbyqxmd.com/read/29049793/triangular-resection-versus-neochordal-replacement-for-posterior-leaflet-prolapse-a-morphological-assessment
#1
Wenrui Ma, Jiafei Chen, Wei Zhang, Weihua Wu, Wei Ye, Wei Shi, Ye Kong
OBJECTIVES: To evaluate the morphological reconstruction as assessed by 3D transoesophageal echocardiography after triangular resection and neochordal replacement in the treatment of posterior leaflet prolapse. METHODS: We retrospectively selected 46 patients with isolated posterior leaflet prolapse who were undergoing mitral valve repair using triangular resection ( n  = 20) and neochordal replacement ( n  = 26) techniques. Sixty patients without valvular heart disease were also included as the control group...
August 14, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049781/does-mitral-valve-repair-matter-in-infants-with-ventricular-septal-defect-combined-with-mitral-regurgitation
#2
Yuriy Y Kulyabin, Ilya A Soynov, Alexey V Zubritskiy, Alexey V Voitov, Nataliya R Nichay, Yuriy N Gorbatykh, Alexander V Bogachev-Prokophiev, Alexander M Karaskov
OBJECTIVES: This study aimed to assess mitral valve function after repair of ventricular septal defect (VSD) combined with mitral regurgitation (MR) in the mid-term follow-up period, to evaluate the clinical utility of simultaneous mitral valve repair (MVR). METHODS: From June 2005 to March 2014, 60 patients with VSD and MR underwent surgical treatment. After performing propensity score analysis (1:1) for the entire sample, 46 patients were selected and divided into 2 groups: those with VSD closure and MVR (VSD + MVR, 23 patients) and those with VSD closure without mitral valve intervention (VSD only, 23 patients)...
August 14, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29042413/mitral-leaflet-changes-following-myocardial-infarction-clinical-evidence-for-maladaptive-valvular-remodeling
#3
Jonathan Beaudoin, Jacob P Dal-Bianco, Elena Aikawa, Joyce Bischoff, J Luis Guerrero, Suzanne Sullivan, Philipp Emanuel Bartko, Mark D Handschumacher, Dae-Hee Kim, Jill Wylie-Sears, Jacob Aaron, Robert A Levine
BACKGROUND: Ischemic mitral regurgitation (MR) is classically ascribed to functional restriction of normal leaflets, but recent studies have suggested post-myocardial infarction (MI) mitral valve (MV) leaflet fibrosis and thickening, challenging valve normality. Progression of leaflet thickness post-MI has not been studied. We hypothesized that excessive MV remodeling post-MI contributes to MR. Our objectives are to characterize MV changes after MI and relate them to MR. METHODS AND RESULTS: Three groups of 40 patients with serial echocardiograms over a mean of 23...
November 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29034311/left-atrial-deformation-useful-index-for-early-detection-of-cardiac-damage-in-chronic-mitral-regurgitation
#4
REVIEW
M Cameli, E Incampo, S Mondillo
In chronic mitral regurgitation (MR) left atrium is one of the first cardiac structures that is involved in remodeling and ultrastructural changes for a progressive volume overload. Severe left atrial (LA) dilation on echocardiography and new onset of atrial fibrillation in asymptomatic patients with preserved Left Ventricular (LV) function, appeared as a Class IIb recommendation for consideration for surgical mitral valve repair in the actual guidelines. However, before atrial dilatation and dysfunction, several ultrastructural changes appear in the atrial muscle tissue that are difficult to identify with the standard echocardiography...
December 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29033048/comparison-of-outcome-after-percutaneous-mitral-valve-repair-with-the-mitraclip-in-patients-with-versus-without-atrial-fibrillation
#5
Juliëtte F Velu, Friso A Kortlandt, Tom Hendriks, Remco A J Schurer, Ad J van Boven, Karel T Koch, M Marije Vis, Jose P Henriques, Jan J Piek, Ben J L Van den Branden, Jeroen Schaap, Benno J Rensing, Martin J Swaans, Berto J Bouma, Jan A S Van der Heyden, Jan Baan
Percutaneous mitral valve repair with the MitraClip is an established treatment for patients with mitral regurgitation (MR) who are inoperable or at high risk for surgery. Atrial Fibrillation (AF) frequently coincides with MR, but only scarce data of the influence of AF on outcome after MitraClip is available. The aim of the current study was to compare the clinical outcome after MitraClip treatment in patients with versus without atrial fibrillation. Between January 2009 and January 2016, all consecutive patients treated with a MitraClip in 5 Dutch centers were included...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29031415/usefulness-of-the-crt-score-for-shared-decision-making-in-cardiac-resynchronization-therapy-in-patients-with-a-left-ventricular-ejection-fraction-of-%C3%A2-35
#6
Ulas Höke, Bart Mertens, Mand J H Khidir, Martin J Schalij, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan
Individualized estimation of prognosis after cardiac resynchronization therapy (CRT) remains challenging. Our aim was to develop a multiparametric prognostic risk score (CRT-SCORE) that could be used for patient-specific clinical shared decision making about CRT implantation. The CRT-SCORE was derived from an ongoing CRT registry, including 1,053 consecutive patients (age 67 ± 10 years, 76% male). Using preimplantation variables, 100 multiple imputed datasets were generated for model calibration. Based on multivariate Cox regression models, cross-validated linear prognostic scores were calculated, as well as survival fractions at 1 and 5 years...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#7
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29026415/two-cases-of-parachute-tricuspid-valve-confirmed-by-three-dimensional-echocardiography
#8
Hedieh Alimi, Afsoon Fazlinezhad
BACKGROUND: Parachute tricuspid valve is a rare congenital malformations explained in the literature. In most cases, this malformation coexists with other congenital defects. The importance of this condition depends on its functional consequences. CASE REPORT: First case was a 52-year-old female patient presented with palpitation. She had a history of paroxysmal supraventricular tachycardia. Transthoracic echocardiography revealed large secundum type atrial septal defect and all the tricuspid valve leaflets appeared to be connected to a single calcified papillary muscle in right ventricle suggestive of parachute tricuspid valve...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29022825/mitraclip-and-mitral-annuloplasty-device-as-a-bridge-to-transplantation
#9
Nainar Madhu Sankar, Salla Sweta Ramani, Rajaram Anantharaman, Kotturathu Mammen Cherian
A 42-year-old man with dilated cardiomyopathy and endstage heart failure was evaluated for heart transplantation. He received a MitraClip and Carillon annuloplasty device for functional mitral regurgitation as palliation for his heart failure. Subsequently, he underwent successful heart transplantation.
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29021862/adaptive-cardiac-resynchronization-therapy-for-dilated-cardiomyopathy-with-functional-mitral-regurgitation
#10
Yoshiki Nagata, Yoichiro Nakagawa, Yusuke Takeda, Kenji Emoto, Masaki Kinoshita, Akio Chikata, Michiro Maruyama, Kazuo Usuda
We report the case of a man in his 60s who had dilated cardiomyopathy with severe functional mitral regurgitation. Four years after a cardiac resynchronization therapy (CRT) device with an implantable cardioverter defibrillator was implanted, this device was replaced with an adaptive CRT device because of battery consumption. Seven months after replacement of this device, the left ventricular pacing to right ventricular activation and the atrioventricular delay from automatic adjustments contributed to less functional mitral regurgitation...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29020337/refining-the-prognostic-impact-of-functional-mitral-regurgitation-in-chronic-heart-failure
#11
Georg Goliasch, Philipp E Bartko, Noemi Pavo, Stephanie Neuhold, Raphael Wurm, Julia Mascherbauer, Irene M Lang, Guido Strunk, Martin Hülsmann
Aims: Significant efforts are currently undertaken to reduce functional mitral regurgitation (FMR) in patients with chronic heart failure in the hope to improve prognosis. We aimed to assess the prognostic impact of FMR in heart failure with reduced ejection fraction (HFrEF) under optimal medical therapy (OMT) and various conditions of HFrEF. We further intended to identify a heart failure phenotype, where FMR is most likely a driving force and not a mere bystander of the disease. Methods and results: We prospectively included 576 consecutive HFrEF patients into our long-term observational study...
July 25, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28994686/lutembacher-syndrome-dilemma-of-doing-a-tricuspid-annuloplasty
#12
A V Varsha, Gladdy George, Raj Sahajanandan
We discuss the case of a 24-year-old woman with Lutembacher syndrome and severe tricuspid regurgitation (TR) who underwent surgical closure of atrial septal defect and mitral valve replacement without tricuspid annuloplasty despite a severe TR and a large tricuspid annulus on preoperative echo. The pathophysiology of Lutembacher syndrome is discussed below. The utility of perioperative echocardiography in assessing the annular diameter, tenting area and coaptation depth and thus providing insights into the functioning of the tricuspid valve will also be emphasized...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28994679/ischemic-mitral-regurgitation
#13
REVIEW
Praveen Kerala Varma, Neethu Krishna, Reshmi Liza Jose, Ashish Narayan Madkaiker
Ischemic mitral regurgitation (IMR) is a frequent complication of left ventricular (LV) global or regional pathological remodeling due to chronic coronary artery disease. It is not a valve disease but represents the valvular consequences of increased tethering forces and reduced closing forces. IMR is defined as mitral regurgitation caused by chronic changes of LV structure and function due to ischemic heart disease and it worsens the prognosis. In this review, we discuss on etiology, pathophysiology, and mechanisms of IMR, its classification, evaluation, and therapeutic corrective methods of IMR...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28994654/impact-of-concomitant-mitral-regurgitation-on-transvalvular-gradient-and-flow-in-severe-aortic-stenosis-a-systematic-ex-vivo-analysis-of-a-subentity-of-low-flow-low-gradient-aortic-stenosis
#14
Felix Katte, Marcus Franz, Christian Jung, Hans R Figulla, David M Leistner, Philipp Jakob, Barbara E Stähli, Daniel Kretzschmar, Alexander Lauten
AIMS: Evaluation of aortic stenosis(AS) is based on measurement of mean transvalvular gradient(MPG), flow velocity(vmax) and aortic valve area(AVA). Objective of the present study was to analyse the impact of systemic hemodynamic variables and concomitant mitral regurgitation(MR) on aortic MPG, vmax and AVA in severe AS. METHODS AND RESULTS: A pulsatile circulatory model was designed to study function and interdependence of stenotic aortic and insufficient mitral prosthetic valves (n=8; effective regurgitation orifice (EROA)<0...
October 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28991057/minimally-invasive-mitral-valve-annuloplasty-with-realignment-of-both-papillary-muscles-for-correction-of-type-iiib-functional-mitral-regurgitation
#15
Evaldas Girdauskas, Lenard Conradi, Eva Karolina Harmel, Hermann Reichenspurner
OBJECTIVE: Pathophysiological background of type IIIb functional mitral regurgitation (FMR) is a progressively increasing distance between papillary muscle tips and mitral annular plane. Standard surgical treatment of such FMR by means of undersized mitral annuloplasty is associated with a high recurrence rate. METHODS: We propose a modified subannular maneuver to correct type IIIb FMR while combining undersized annuloplasty with a controlled realignment of both papillary muscles, thereby fixing the distance between mitral annular plane and papillary muscle tips...
September 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28988424/maintenance-of-valvular-integrity-with-impella-left-heart-support-results-from-the-multicenter-protect-ii-randomized-study
#16
James A Goldstein, Simon R Dixon, Pamela S Douglas, E Magnus Ohman, Jeffrey Moses, Jeffrey J Popma, William W O'Neill
BACKGROUND: The Impella 2.5 axial flow pump, which is positioned across the aortic valve, is widely employed for hemodynamic support. The present study compared structural and functional integrity of the left heart valves in patients undergoing Impella vs intra-aortic balloon pump in the randomized PROTECT II trial. METHODS AND RESULTS: Transthoracic echocardiograms were performed at baseline, 1 and 3 months in 445 patients in the PROTECT II trial. Serial studies were analyzed by an independent echocardiography core laboratory for aortic and mitral valve structure and function, and left ventricular ejection fraction (LVEF)...
October 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28982556/early-outcomes-of-percutaneous-transvenous-transseptal-transcatheter-valve-implantation-in-failed-bioprosthetic-mitral-valves-ring-annuloplasty-and%C3%A2-severe-mitral-annular-calcification
#17
Mackram F Eleid, Brian K Whisenant, Allison K Cabalka, Mathew R Williams, Mohammed Nejjari, David Attias, Neil Fam, Nicholas Amoroso, Thomas A Foley, Peter M Pollak, Oluseun O Alli, Sorin V Pislaru, Sameh M Said, Joseph A Dearani, Charanjit S Rihal
OBJECTIVES: The aim of this study was to examine 1-year outcomes of transseptal balloon-expandable transcatheter heart valve implantation in failed mitral bioprosthesis, ring annuloplasty, and mitral annular calcification (MAC). BACKGROUND: Immediate outcomes following transseptal mitral valve implantation in failed bioprostheses are favorable, but data on subsequent outcomes are lacking. METHODS: Percutaneous transseptal implantation of balloon-expandable transcatheter heart valves was performed in 87 patients with degenerated mitral bioprostheses (valve in valve [VIV]) (n = 60), previous ring annuloplasty (valve in ring) (n = 15), and severe MAC (valve in MAC) (n = 12)...
October 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28978263/three-dimensional-transoesophageal-echocardiography-is-crucial-for-valid-assessment-of-mitral-valve-leaflet-morphology-in-severe-mitral-regurgitation-prior-to-interventional-repair
#18
Amr Alfakhouri, Felix Matthias Heidrich, Krunoslav Michael Sveric, Christian Pfluecke, Heda Kvakan, Silvio Quick, Uwe Speiser, Akram Youssef, Ruth H Strasser, Stephan Wiedemann
BACKGROUND: Interventional mitral valve (MV) repair of severe symptomatic mitral regurgitation (MR) is a therapeutic option in high-risk surgical or inoperable patients. Assessment of the MV remains a crucial part of pre-interventional screening. Three-dimensional transoesophageal echocardiography (3D-TOE) may compensate for well-known pitfalls that occur in 2D-TOE. PURPOSE: We investigated whether the functional length of the central segments of the posterior and anterior MV leaflets (PML-P2 and AML-A2) is more reliably determined by 3D-TOE full volume datasets (3D-MPR) or orthogonal biplane-imaging (Xplane) when compared to 2D-TOE...
October 5, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28977386/lower-limit-of-normality-and-clinical-relevance-of-left-ventricular-early-diastolic-strain-rate-for-the-detection-of-left-ventricular-diastolic-dysfunction
#19
Daniel A Morris, Masaaki Takeuchi, Satoshi Nakatani, Yutaka Otsuji, Evgeny Belyavskiy, Radhakrishnan Aravind Kumar, Athanasios Frydas, Martin Kropf, Robin Kraft, Esteban Marquez, Engin Osmanoglou, Maximilian Krisper, Clemens Köhncke, Leif-Hendrik Boldt, Wilhelm Haverkamp, Carsten Tschöpe, Frank Edelmann, Burkert Pieske, Elisabeth Pieske-Kraigher
Aims: The aim of the present study was to determine the lower limit of normality and the clinical relevance of left ventricular (LV) early diastolic strain rate (LVSRe) for the detection of LV diastolic dysfunction (LVDD). Methods and results: Using 2D speckle-tracking echocardiography, we analysed 377 healthy subjects and 475 patients with risk for LVDD with preserved LV ejection fraction (LVEF). The normal range of LVSRe analysing the healthy subjects was 1.56 ± 0...
August 3, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28976383/-approach-to-mitral-valve-diseases-in-the-elderly
#20
Dilek Yeşilbursa
Valvular disease continues to be an important cause of morbidity and mortality across the globe with an increasing number of elderly patients affected by degenerative valvular diseases. Mitral valve disease is the most common of the valvular heart disorders, particularly in ageing populations, with a prevalence of more than 10% in people aged older than 75 years. Mitral regurgitation (MR) is divided into either primary (or organic) or secondary (or functional) MR. It is necessary to distinguish primary from secondary MR because these diseases differ not only by their cause, but also by their prognosis and management...
September 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
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