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functional mitral regurgitation

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https://www.readbyqxmd.com/read/29687703/surgical-myocardial-revascularization-in-patients-with-reduced-systolic-left-ventricular-function
#1
Piergiorgio Bruno, Mauro Iafrancesco, Massimo Massetti
Surgical myocardial revascularization in patients with reduced left ventricular function has been a matter of debate for decades. Recently published 10-years extension follow-up of the STICH trial have conclusively demonstrated benefit of surgical myocardial revascularization in patients with significant coronary artery disease and low left ventricular ejection fraction. However, selection of patients for surgery remains challenging as well as decision to perform percutaneous rather than surgical revascularization in this class of patients...
April 20, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29678512/galectin-3-is-associated-with-left-ventricular-reverse-remodeling-and-outcome-after-percutaneous-mitral-valve-repair
#2
Christine S Zuern, Niklas Floss, Iris I Mueller, Christian Eick, Martin Duckheim, Johannes Patzelt, Meinrad Gawaz, Andreas E May, Karin A L Mueller
BACKGROUND: Plasma Galectin-3 is a marker of myocardial inflammation and fibrosis, was associated with left ventricular (LV) reverse remodeling after conventional surgical mitral valve repair (MVR) and predicted clinical events in patients undergoing transcatheter aortic valve replacement (TAVR). We aimed to evaluate the association between pre-interventional Galectin-3 levels and (1) reverse LV remodeling and (2) major adverse cardiovascular events (MACE) in patients undergoing percutaneous MVR...
April 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29676043/mitral-valve-interventions-in-heart-failure
#3
REVIEW
Daniel Lavall, Andreas Hagendorff, Stephan H Schirmer, Michael Böhm, Michael A Borger, Ulrich Laufs
Secondary mitral regurgitation (MR) results from left ventricular dilatation and dysfunction. Quantification of secondary MR is challenging because of the underlying myocardial disease. Clinical and echocardiographic evaluation requires a multi-parametric approach. Severe secondary MR occurs in up to one-fourth of patients with heart failure with reduced ejection fraction, which is associated with a mortality rate of 40% to 50% in 3 years. Percutaneous edge-to-edge mitral valve repair (MitraClip) has emerged as an alternative to surgical valve repair to improve symptoms, functional capacity, heart failure hospitalizations, and cardiac haemodynamics...
April 19, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29657253/minimally-invasive-mitral-valve-repair-through-right-minithoracotomy-11-year-single-institute-experience
#4
Taichi Sakaguchi, Toshinori Totsugawa, Masahiko Kuinose, Kentaro Tamura, Arudo Hiraoka, Genta Chikazawa, Hidenori Yoshitaka
BACKGROUND: Although minimally invasive mitral valve repair (MIMVR) is increasingly being performed, only a few clinical studies from Japanese institutions have been reported.Methods and Results:From 2006 to 2017, 387 consecutive patients (135 females, mean age 56±13 years) underwent an initial isolated MIMVR through a right minithoracotomy. The mitral etiology was degenerative in 348, functional in 22, and endocarditis in 13 cases. Repair techniques included leaflet resection/plication in 280, chordal reconstruction in 109, and annuloplasty alone in 24 patients, and concomitant procedures included tricuspid valve repair and atrial fibrillation ablation in 70 (18...
April 13, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29627180/transatrial-implantation-of-a-transcatheter-heart-valve-for-severe-mitral-annular-calcification
#5
Fabien Praz, Omar K Khalique, Raymond Lee, Ramesh Veeragandham, Hyde Russell, Mayra Guerrero, Ashequl M Islam, David W Deaton, Tsuyoshi Kaneko, Susheel K Kodali, Martin B Leon, Vinayak Bapat, Hiroo Takayama, Michael A Borger, Isaac George
OBJECTIVE: To assess the outcomes of transatrial implantation of a transcatheter heart valve (THV) for the treatment of mitral valve disease with severe mitral annular calcification (MAC). METHODS: Implantation of a balloon-expandable THV was performed on cardiopulmonary bypass via left atrial exposure in patients considered at risk for left ventricular outflow tract obstruction. The anterior mitral valve leaflet was systematically resected and pledgeted sutures were placed to enhance stability and reduce paravalvular leak...
March 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29623174/a-double-whammy-severe-aortic-stenosis-and-cocaine-overwhelm-the-mitral-valve
#6
Rohit Maini, Jonathan Lim, Jing Liu, Itamar Birnbaum, Farooq Mirza, Nasser Lakkis, Ihab Hamzeh
A 50-year-old man presented with acute onset dyspnea following cocaine use. He had severe aortic stenosis (AS), mild mitral regurgitation (MR) due to mitral valve prolapse, and no coronary artery disease on recent coronary angiography. He was in acute heart failure with signs of impending cardiogenic shock. Urgent bedside echocardiography revealed hyperdynamic left ventricular systolic function with acute severe MR from a ruptured chordae tendineae. The acute cocaine-induced spike of his already elevated left ventricular systolic pressure from severe AS likely precipitated chordal rupture of his vulnerable mitral valve...
January 2018: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29622987/outcome-of-transcatheter-aortic-valve-implantation-in-high-risk-patients-with-severe-aortic-stenosis
#7
Hamdy Soliman, Khlid Alrabaat, Tarek Aboalaazm, Shaimaa Mostafa, Asaad Samy
Aim: To assess outcome of TAVI in high risk patients with severe symptomatic aortic stenosis. Patients and methods: 40 patients with symptomatic severe aortic stenosis and high risk underwent TAVI with implantation of either Sapien XT valve or Core Valve and followed for 6 months. Device success, cardiovascular mortality, myocardial infarction, stroke, life-threatening bleeding and vascular complications were defined according to Valve Academic Research Consortium definitions...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622985/the-value-of-three-dimensional-color-doppler-trans-esophageal-echocardiography-in-predicting-the-number-of-mitraclip-devices-needed-during-the-procedure
#8
Hani M Mahmoud, Ali M Al-Ameen, Mohamed H Hassan, Tarek Badr, Hesham Nieem, Ahmed A Shaheen, Abdullah E Ghabashi
Purpose: During MitraClip procedure, one or more clips might be needed to effectively reduce the mitral regurgitation (MR). Three-dimensional vena-contracta (3D-VC) assessed by color Doppler three-dimensional trans-esophageal echocardiography (3D-TEE) was proven to be well correlated with MR severity. However, its role in predicting the number of MitraClip devices needed during the procedure was not fully determined. Aim of this study is to assess the predictive value of 3D-VC area & length in determining the number of clips needed during the procedure...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622984/tricuspid-valve-repair-with-dacron-band-versus-devega-or-segmental-annuloplasty-hospital-outcome-and-short-term-results
#9
Ahmed Abdelgawad, Mona Ramadan, Heba Arafat, Ahmed Abdel Aziz
Background: The purpose of this study was to compare the hospital outcome and short term results of tricuspid valve (TV) repair with three repair techniques for functional tricuspid regurgitation (TR), namely, flexible Dacron band, DeVega and segmental annuloplasty. Methods: A total of 60 patients underwent TV repair at National Heart Institute from January 2013 to November 2014, of which 20 had DeVega procedure (DV), 20 had a segmental annuloplasty (SA) procedure and 20 had a Dacron band (DB) procedure...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622967/the-value-of-urotensin-ii-in-patients-with-left-sided-rheumatic-valvular-regurgitation
#10
Ibrahim Elmadbouh, Mahmoud Ali Soliman, Ahmed Abdallah Mostafa, Haitham Ahmed Heneish
Aims: Rheumatic valve diseases are most common etiological valve diseases in developing countries. Urotensin II is cardiovascular autacoid/hormone and may be associated with patients of heart valve diseases. The present study was to measure plasma urotensin II concentrations in patients with left-sided rheumatic valve diseases such as mitral regurgitation (MR) and aortic regurgitation (AR), and to examine its correlation with severity of valve impairment, function (New York Heart association, NYHA) class and pulmonary artery pressure (PAP)...
June 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622911/submitral-left-ventricular-aneurysm-associated-with-thrombus
#11
Abdusamed Adem Abdusamed, Hailu Abera Mulatu, Reinaldo Nunez Martinez
Background: Submitral left ventricular aneurysm is a rarely reported cardiac abnormality that is encountered commonly among blacks. So far, only one case has been reported from Ethiopia and East Africa.Our aim is to report an interesting and rare case that we encountered at St. Paul's Hospital Millennium Medical College. Methods: In April 2017, a 25-year-old patient havingsubmitral left ventricular aneurysm with New York Heart Association (NYHA) class IV heart failure and mild left ventricular systolic dysfunctionreceived medical treatment at our institution...
January 2018: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29619932/mortality-and-morbidity-in-patients-with-osteogenesis-imperfecta-in-denmark
#12
Lars Folkestad
Ostegenesis imperfecta (OI) is a hereditary disease of the connective tissue caused by mutations to, mainly, the genes that are involved in the biosynthesis of collagen type 1. Patients are grouped according to clinical severity and mode of inheritance according to Sillence's classification (originally 1979, updated 2014). According to our data, the population prevalence of OI in Denmark was 10.3 per 100,000, with 575 patients registered with an OI diagnosis in the National Patient Register and alive at the end of 2012 out of a total population of 5,602,628 persons...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29617497/opcabg-for-moderate-cimr-in-elderly-patients-a-superior-option
#13
Amber Malhotra, Chandrasekaran Ananthanarayanan, Vivek Wadhawa, Sumbul Siddiqui, Pranav Sharma, Kartik Patel, Komal Shah, Pratik Shah
OBJECTIVE: To compare the early and late outcomes of off-pump coronary artery bypass grafting and coronary artery bypass graft + mitral valve repair in elderly patients with moderate chronic ischemic mitral regurgitation. METHODS: One hundred and fifty elderly (age > 70 years) patients with moderate chronic ischemic mitral regurgitation who underwent off-pump coronary artery bypass grafting (n=95) or coronary artery bypass graft + mitral valve repair (n=55) between January 2007 and December 2014 were studied...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29608495/medical-management-of-rheumatic-heart-disease-a-systematic-review-of-the-evidence
#14
E Anne Russell, Warren F Walsh, Ben Costello, Alex Ja McLellan, Alex Brown, Christopher M Reid, Lavinia Tran, Graeme P Maguire
Rheumatic heart disease (RHD) is an important cause of heart disease globally. Its management can encompass medical and procedural (catheter and surgical) interventions. Literature pertaining to the medical management of RHD from PubMed 1990-2016 and via selected article reference lists was reviewed. Areas included symptom management, left ventricular (LV) dysfunction, rate control in mitral stenosis (MS), atrial fibrillation (AF), anticoagulation, infective endocarditis prophylaxis and management in pregnancy...
March 30, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29602220/degenerative-mitral-regurgitation-predicts-worse-outcomes-in-patients-undergoing-transcatheter-aortic-valve-replacement
#15
Bryan Kindya, Elisha Ouzan, Stamatios Lerakis, Erhan Gonen, Vasilis Babaliaros, Eren Karayel, Vinod H Thourani, Israel Gotsman, Chandan M Devireddy, Haim D Danenberg, Bradley G Leshnower, Ronen Beeri, Yi-An Ko, Dan Gilon, Hina Ahmed, Chang Liu, Chaim Lotan, Kreton Mavromatis
OBJECTIVES: To evaluate the role mitral regurgitation (MR) etiology and severity play in outcomes for patients undergoing transcatheter aortic valve replacement (TAVR). BACKGROUND: Multiple prior studies have investigated the influence of MR severity on outcomes for patients undergoing TAVR. Less has been published regarding the effects of MR etiology on outcomes, including its impact on heart failure hospitalization. METHODS: Two hundred and seventy patients undergoing TAVR at 2 hospitals were enrolled...
March 30, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29581084/beyond-the-5-year-horizon-long-term-outcome-of-high-risk-and-inoperable-patients-undergoing-tavr-with-first-generation-devices
#16
Marcus-André Deutsch, Magdalena Erlebach, Melchior Burri, Alexander Hapfelmeier, Olivia Ganga Witt, Johannes Amadeus Ziegelmueller, Michael Wottke, Hendrik Ruge, Markus Krane, Nicolo Piazza, Sabine Bleiziffer, Rüdiger Lange
AIMS: We sought to determine the long-term outcome of high-risk patients who underwent transcatheter aortic valve replacement (TAVR) with first-generation devices with a focus on an identification of predictors for mortality and valve durability. METHODS AND RESULTS: Consecutive patients in our prospective single-center registry undergoing TAVR with first-generation devices (n=214 CoreValve; n=86 Sapien) between 06/2007 and 07/2009 were retrospectively analysed (n=300, mean age 81...
March 27, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29579826/cardiac-remodeling-in-structure-and-function-six-months-after-kidney-transplantation
#17
L Garcia-Covarrubias, K Hernández, I Castro, H Hinojosa, L Molina, O Bazan, C Gutierrez, A Reding-Bernal, J Barragan, A García, D Fernandez, P Fragoso, J M Torres, D Ortuño, P Prieto, H Diliz
BACKGROUND: Cardiovascular disease accounts for 35% to 50% of the causes of mortality in chronic kidney disease. The majority of patients in substitution therapy in Mexico are subdialyzed owing to limited economic resources. This produces more cardiac deterioration than described in the statistics and has a direct impact on the prognosis of kidney transplantation. The aim of this work was to demonstrate and to quantify the improvement in the echocardiographic parameters 6 months after renal transplantation in patients with stable renal function...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29570208/sheep-can-be-used-as-animal-model-of-regional-myocardial-remodelling-and-controllable-work
#18
Jürgen Duchenne, Piet Claus, Efstathios D Pagourelias, Razvan O Mada, Joeri Van Puyvelde, Kathleen Vunckx, Eric Verbeken, Olivier Gheysens, Filip Rega, Jens-Uwe Voigt
BACKGROUND: A-V-sequential pacing has been shown to induce reversible conduction delay and subsequent asymmetric remodelling of the left ventricle (LV) in dogs and pigs. Both species have disadvantages in animal experiments. Therefore aim of this study focusses at developing a more feasible and easy-to-use animal model in sheep. METHODS: Dual-chamber pacing (DDD) pacemakers (right atrium + right ventricular free wall) were surgically implanted in 13 sheep. All animals underwent 8 weeks of chronic rapid pacing at 180 bpm...
March 23, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29553091/prevalence-and-prognostic-significance-of-functional-mitral-and-tricuspid-regurgitation-despite-preserved-left-ventricular-ejection-fraction-in-atrial-fibrillation-patients
#19
Yukio Abe, Kanako Akamatsu, Kazato Ito, Yoshiki Matsumura, Kenji Shimeno, Takahiko Naruko, Yosuke Takahashi, Toshihiko Shibata, Minoru Yoshiyama
BACKGROUND: We investigated the prevalence and prognostic significance of functional mitral regurgitation (MR) and tricuspid regurgitation (TR) in patients with atrial fibrillation (AF) and preserved left ventricular ejection fraction (LVEF).Methods and Results:We retrospectively studied the cases of 11,021 consecutive patients who had undergone transthoracic echocardiography. AF appeared in 1,194 patients, and we selected 298 with AF and LVEF ≥50% but without other underlying heart diseases...
March 16, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29548906/seeing-is-not-always-believing-another-dimension-of-functional-mitral-regurgitation
#20
EDITORIAL
Elena Ashikhmina, Hartzell Schaff
No abstract text is available yet for this article.
February 9, 2018: Journal of Cardiothoracic and Vascular Anesthesia
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