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functional mitral regurgitation

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https://www.readbyqxmd.com/read/28100876/primary-percutaneous-coronary-intervention-followed-by-valve-surgery-for-acute-coronary-syndrome-at-left-main-trunk-complicated-with-severe-aortic-stenosis
#1
Akira Shikuma, Jun Shiraishi, Kazunari Okawa, Masaki Yashige, Keisuke Shoji, Daisuke Ito, Masayoshi Kimura, Eigo Kishita, Yusuke Nakagawa, Masayuki Hyogo, Akiyuki Takahashi, Takahisa Sawada
An 89-year-old woman appeared to have acute coronary syndrome at the left main trunk (LMT) complicated with severe aortic stenosis, moderate-severe mitral regurgitation, depressed left ventricular (LV) function, and multivessel disease. Because of sustained hypotension even under intra-aortic balloon pumping support during emergency coronary angiograhy, we performed primary percutaneous coronary intervention solely for the LMT lesion using a bare metal stent, leading to recovery from the shock state. On the second hospital day, based on our heart-team consensus, we performed aortic valve replacement and coronary artery bypass grafting surgery, and added edge-to-edge repair (Alfieri stitch) of the mitral valve, resulting in complete revascularization and dramatically improved LV function...
January 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28100340/-outcome-comparison-of-different-therapy-procedures-in-surgical-high-risk-elderly-patients-with-severe-aortic-stenosis
#2
Y Q Ye, Y T Wang, Z Li, M Y Wang, H Y Xu, W J Zhang, Q R Liu, G N Niu, Y J Wu
Objective: To compare the outcome of surgical high-risk elderly patients with severe aortic stenosis(SAS) treated by different therapy procedures, including transcatheter aortic valve implantation(TAVI), surgical aortic valve replacement(SAVR), and drug therapy. Methods: We retrospectively analyzed the clinical data of 242 surgical high-risk elderly (age ≥65 years old) SAS patients hospitalized in Fuwai Hospital between September 2012 and June 2015. According to the treatment method, patients were divided into TAVI group (81 cases), SAVR group (59 cases) and drug therapy group (102 cases)...
January 25, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28097185/immediate-improvement-in-severe-mitral-regurgitation-after-aortic-valve-replacement-for-severe-aortic-insufficiency
#3
Ahmad Zeeshan, Mojun Zhu, John A Elefteriades
A 57-year-old male with ascending aortic aneurysm, severe aortic regurgitation, and severe mitral regurgitation (MR) underwent ascending aortic replacement and aortic valve replacement. MR in this patient with normal mitral valve morphology was considered secondary to aortic valve incompetency. Consequently, a surgical approach to restore aortic valve function was adopted with successful MR resolution. This case report demonstrates the possibility of reversing early functional mitral regurgitation without surgically approaching the mitral valve...
June 2016: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/28096824/extended-myectomy-in-the-treatment-of-patients-with-hypertrophic-obstructive-cardiomyopathy
#4
Mateusz Kuć, Piotr Kołsut, Jacek Różański, Maciej Dąbrowski, Mariusz Kłopotowski, Magda Kumor, Mirosław Kowalski, Natalia Kopyłowska, Jarosław Kuriata, Mariusz Kuśmierczyk
INTRODUCTION: Partial resection of the septal muscle is a well-established and effective method of surgical treatment for patients with hypertrophic obstructive cardiomyopathy (HOCM). The procedure is characterized by a low operative mortality rate and long-term clinical improvement that has been confirmed in numerous publications. Mitral insufficiency in patients with HOCM is mostly functional due to the effect of systolic anterior motion (SAM). AIM: To present the early results of surgical treatment provided to HOCM patients and to compare the effectiveness of two surgical procedures: isolated myectomy and myectomy combined with mitral valve replacement...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28093494/exercise-dynamics-in-secondary-mitral-regurgitation-pathophysiology-and-therapeutic-implications
#5
Philippe B Bertrand, Ehud Schwammenthal, Robert A Levine, Pieter M Vandervoort
Secondary mitral valve regurgitation (MR) remains a challenging problem in the diagnostic workup and treatment of patients with heart failure. Although secondary MR is characteristically dynamic in nature and sensitive to changes in ventricular geometry and loading, current therapy is mainly focused on resting conditions. An exercise-induced increase in secondary MR, however, is associated with impaired exercise capacity and increased mortality. In an era where a multitude of percutaneous solutions are emerging for the treatment of patients with heart failure, it becomes important to address the dynamic component of secondary MR during exercise as well...
January 17, 2017: Circulation
https://www.readbyqxmd.com/read/28090292/a-new-look-at-bronchopulmonary-dysplasia-postcapillary-pathophysiology-and-cardiac-dysfunction
#6
Arvind Sehgal, Andra Malikiwi, Eldho Paul, Kenneth Tan, Samuel Menahem
Pulmonary hypertension (PH) and right ventricular function are the focus of cardiovascular effects of bronchopulmonary dysplasia (BPD). We assessed cardiac indexes reflecting systemic afterload and pulmonary venous back pressure as pathophysiologic factors. Cardiac parameters were measured by conventional echocardiography in 20 preterm infants with severe BPD and compared with those of 10 preterm infants with no BPD and 20 healthy term infants. In infants with severe BPD, PH was noted in 5 (25%) by tricuspid regurgitation Doppler jet ≥2...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28089953/transcatheter-treatment-of-severe-tricuspid-regurgitation-using-the-edge-to-edge-repair-technique
#7
Daniel Braun, Michael Nabauer, Mathias Orban, Martin Orban, Lisa Gross, Andrea Englmaier, Diana Rösler, Julinda Mehilli, Axel Bauer, Christian Hagl, Steffen Massberg, Jörg Hausleiter
AIMS: The aim of this study was to investigate the procedural feasibility and short-term durability of the transcatheter tricuspid valve edge-to-edge repair technique in highly symptomatic patients with severe tricuspid regurgitation (TR). METHODS AND RESULTS: Eighteen consecutive patients suffering from severe right-sided heart failure (NYHA Class III-IV), primarily due to moderate to severe tricuspid regurgitation, were included in the study. Applying a modified steering technique for the clip delivery system, six patients were treated for isolated severe TR, while 12 patients were treated for moderate to severe TR and concomitant severe mitral regurgitation...
January 17, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28077817/prognostic-significance-of-non-dilated-left-ventricular-size-and-mitral-regurgitation-in-patients-with-dilated-phase-of-hypertrophic-cardiomyopathy
#8
Toru Kubo, Yuichi Baba, Takayoshi Hirota, Katsutoshi Tanioka, Naohito Yamasaki, Yoshinori L Doi, Hiroaki Kitaoka
Although a subtype of hypertrophic cardiomyopathy (HCM), dilated phase of HCM (D-HCM) characterized by left ventricular (LV) systolic dysfunction, has been reported to have a poor prognosis, some patients with D-HCM survive for a relatively long period. The degree of LV dilatation and functional mitral regurgitation (MR) are generally thought to be important predictors of poor prognosis in patients with LV systolic dysfunction. However, there is little information available on the relations among LV size, presence of significant MR, and prognosis in D-HCM patients...
January 11, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28075037/gauging-the-response-to-cardiac-resynchronization-therapy-the-important-interplay-between-predictor-variables-and-definition-of-a-favorable-outcome
#9
Milan Petrovic, Marija Petrovic, Goran Milasinovic, Bosiljka Vujisic Tesic, Danijela Trifunovic, Olga Petrovic, Ivana Nedeljkovic, Ivana Petrovic, Marko Banovic, Marija Boricic-Kostic, Jelena Petrovic, Ross Arena, Dejana Popovic
AIMS: Selection of patients who are viable candidates for cardiac resynchronization therapy (CRT), prediction of the response to CRT as well as an optimal definition of a favorable response, all require further exploration. The purpose of this study was to evaluate the interplay between the prediction of the response to CRT and the definition of a favorable outcome. METHODS: Seventy patients who received CRT were included. All patients met current guideline criteria for CRT...
January 11, 2017: Echocardiography
https://www.readbyqxmd.com/read/28071674/predictors-of-exercise-induced-pulmonary-hypertension-in-patients-with-asymptomatic-degenerative-mitral-regurgitation-mechanistic-insights-from-2d-speckle-tracking-echocardiography
#10
Ryo Kamijima, Kengo Suzuki, Masaki Izumo, Shingo Kuwata, Kei Mizukoshi, Manabu Takai, Seisyou Kou, Akio Hayashi, Keisuke Kida, Tomoo Harada, Yoshihiro J Akashi
Presence of exercise-induced pulmonary hypertension (EIPH) in asymptomatic degenerative mitral regurgitation (DMR) determines prognosis. This study aimed to elucidate the mechanism and predictors of EIPH in asymptomatic DMR. Ninety-one consecutive asymptomatic patients with DMR who underwent exercise stress echocardiography were prospectively included. We obtained various conventional echocardiographic parameters at rest and during peak exercise, as well as left atrial (LA) function at rest using 2-dimensional speckle-tracking analysis...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28070866/finite-element-analysis-of-patient-specific-mitral-valve-with-mitral-regurgitation
#11
Thuy Pham, Fanwei Kong, Caitlin Martin, Qian Wang, Charles Primiano, Raymond McKay, John Elefteriades, Wei Sun
Functional mitral regurgitation (FMR) is a significant complication of left ventricular dysfunction and strongly associated with a poor prognosis. In this study, we developed a patient-specific finite element (FE) model of the mitral apparatus in a FMR patient which included: both leaflets with thickness, annulus, chordae tendineae, and chordae insertions on the leaflets and origins on the papillary muscles. The FE model incorporated human age- and gender-matched anisotropic hyperelastic material properties, and MV closure at systole was simulated...
January 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28066587/comparison-of-outcomes-of-tricuspid-annuloplasty-with-3d-rigid-versus-flexible-prosthetic-ring-for-functional-tricuspid-regurgitation-secondary-to-rheumatic-mitral-valve-disease
#12
Haiping Wang, Xiancheng Liu, Xin Wang, Zhenqian Lv, Xiaojun Liu, Ping Xu
BACKGROUND: Annuloplasty bands and rings are widely used for repairing functional tricuspid regurgitation (FTR). However, the question regarding which is the ideal annuloplasty device remains unclear. The aim of this study was to compare the efficacy and mid-term durability of tricuspid ring annuloplasty for FTR secondary to rheumatic mitral valve disease using flexible Cosgrove-Edwards band and the rigid Edwards MC3 ring (Edwards Lifesciences, LLC, Irvine, CA, USA). METHODS: We retrospectively collected the clinical data of those who underwent mitral valve replacement (MVR) in concomitant with tricuspid ring annuloplasty from 2009 to 2013...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28058268/early-results-of-a-novel-mitral-valve-repair-procedure-the-interpapillary-polytetrafluoroethylene-bridge-formation
#13
Nasri Alotti, Károly Gombocz, Kiddy L Ume, Amer Sayour, Daniel Alejandro Lerman, Aref Rashed
BACKGROUND: Surgical repair of ischemic mitral regurgitation (IMR) associated with chordal rupture in patients with ischemic cardiomyopathy is challenging as it aims to correct several structural pathologies at once. There are ongoing studies evaluating multiple approaches, however long term results are still scarce. METHODS AND RESULTS: 19 patients with IMR underwent mitral valve repair with interpapillary polytetrafluoroethylene (PTFE) bridge and neochordae formation at the Zala County Teaching Hospital...
February 12, 2016: International Journal of Cardiovascular Research
https://www.readbyqxmd.com/read/28041699/impact-of-interventional-edge-to-edge-repair-on-mitral-valve-geometry
#14
Robert Schueler, Sarah Kaplan, Charlotte Melzer, Can Öztürk, Marcel Weber, Jan-Malte Sinning, Armin Welz, Nikos Werner, Georg Nickenig, Christoph Hammerstingl
BACKGROUND/OBJECTIVES: The acute and long-term effects of interventional edge-to-edge repair on the mitral valve (MV) geometry are unclear. We sought to assess MV-annular geometry and the association of changes in MV-diameters with functional response one year after MitraClip implantation. METHODS: Consecutive patients (n=84; age 81.2±8.3years, logistic EuroSCORE 21.7±17.9%) with symptomatic moderate-to-severe mitral regurgitation (MR) underwent MitraClip-procedure...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28040676/the-role-of-papillary-muscle-approximation-in-mitral-valve-repair-for-the-treatment-of-secondary-mitral-regurgitation
#15
REVIEW
Christos G Mihos, Evin Yucel, Orlando Santana
SummarySecondary mitral regurgitation (MR) is present in up to half of patients with dilated cardiomyopathy, and is associated with a poor prognosis. It primarily results from progressive left ventricular remodelling, papillary muscle displacement and tethering of the mitral valve leaflets. Mitral valve repair with an undersized ring annuloplasty is the reparative procedure of choice in the treatment of secondary MR. However, this technique is associated with a 30-60% incidence of recurrent moderate or greater MR at mid-term follow-up, which results in progressive deterioration of left ventricular function and increased morbidity...
December 30, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28040318/transcatheter-mitral-valve-replacement-for-patients-with-symptomatic%C3%A2-mitral%C3%A2-regurgitation-a-global-feasibility-trial
#16
David W M Muller, Robert Saeid Farivar, Paul Jansz, Richard Bae, Darren Walters, Andrew Clarke, Paul A Grayburn, Robert C Stoler, Gry Dahle, Kjell A Rein, Marty Shaw, Gregory M Scalia, Mayra Guerrero, Paul Pearson, Samir Kapadia, Marc Gillinov, Augusto Pichard, Paul Corso, Jeffrey Popma, Michael Chuang, Philipp Blanke, Jonathon Leipsic, Paul Sorajja
BACKGROUND: Symptomatic mitral regurgitation (MR) is associated with high morbidity and mortality that can be ameliorated by surgical valve repair or replacement. Despite this, many patients with MR do not undergo surgery. Transcatheter mitral valve replacement (TMVR) may be an option for selected patients with severe MR. OBJECTIVES: This study aimed to examine the effectiveness and safety of TMVR in a cohort of patients with native valve MR who were at high risk for cardiac surgery...
December 20, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28038944/numerical-simulation-of-mitral-valve-prolapse-considering-the-effect-of-left-ventricle
#17
Seyedvahid Khodaei, Nasser Fatouraee, Malikeh Nabaei
Heart failure is one of the most important issues that has been investigated in recent research studies. Variations that occur in apparatus of mitral valve, such as chordae tendineaea rupture, can affect the valve function during ventricular contraction and lead to regurgitation from the left ventricle into the left atrium. One method for understanding mitral valve function in such conditions is computational analysis. In this paper, we develop a finite element model of mitral valve prolapse, considering the direct effect of left ventricular motion on blood flow interacting with the mitral valve...
December 28, 2016: Mathematical Biosciences
https://www.readbyqxmd.com/read/28038799/the-role-of-myocardial-performance-index-in-assessment-of-left-ventricular-function-in-patients-with-valvular-mitral-regurgitation
#18
Muataz Fawzi Hussein, Samirra Rashid Jabbar Al-Mayahi, Samar I Essa
BACKGROUND: Mitral regurgitation (MR) is the most commonly encountered valve lesion in modern clinical practice. Severe mitral regurgitation may cause systolic dysfunction. Left ventricular ejection fraction may not be an accurate measurement of LV function in patients with mitral insufficiency. Myocardial performance index (MPI) is a simple non invasive measure of myocardial function. METHODS: The study involved 50 patients with valvular mitral regurgitation and 50 healthy subjects as a control group...
December 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28033075/short-term-results-of-sinus-of-valsalva-aneurysm-repair
#19
Khakimjon Abralov, Amonjon Alimov
BACKGROUND: We retrospectively analyzed 65 patients who underwent surgical repair of sinus of Valsalva aneurysm over the last 27 years. METHODS: From January 1, 1988, to October 1, 2015, a total of 65 patients with sinus of Valsalva aneurysm underwent surgical repair in our hospital. There were 41 males (63%) and 24 females (37%), and their age ranged from 5 to 50 years (mean 23 ± 10 years, median 21 years). Out of the 65 patients, 45 (69%) had ruptured sinus of Valsalva aneurysm, 46 (70%) had a ventricular septal defect, and 22 (34%) had aortic valve insufficiency...
January 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28031241/a-tragedy-of-modern-cardiology-using-ejection-fraction-to-gauge-left-ventricular-function-in-mitral-regurgitation
#20
EDITORIAL
Blase A Carabello, Blase A Carabello
No abstract text is available yet for this article.
December 28, 2016: Heart: Official Journal of the British Cardiac Society
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