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functional mitral regurgitation

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https://www.readbyqxmd.com/read/28444570/current-mitraclip-experience-safety-and-feasibility-in-the-netherlands
#1
Z Rahhab, F A Kortlandt, J F Velu, R A J Schurer, V Delgado, P Tonino, A J Boven, B J L Van den Branden, A O Kraaijeveld, M Voskuil, J Hoorntje, M van Wely, K van Houwelingen, G B Bleeker, B Rensing, I Kardys, J Baan, J A S Van der Heyden, N M Van Mieghem
PURPOSE: Data on MitraClip procedural safety and efficacy in the Netherlands are scarce. We aim to provide an overview of the Dutch MitraClip experience. METHODS: We pooled anonymised demographic and procedural data of 1151 consecutive MitraClip patients, from 13 Dutch hospitals. Data was collected by product specialists in collaboration with local operators. Effect on mitral regurgitation was intra-procedurally assessed by transoesophageal echocardiography. Technical success and device success were defined according to modified definitions of the Mitral Valve Academic Research Consortium (MVARC)...
April 25, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28444164/vena-contracta-area-for-severity-grading-in-functional-and-degenerative-mitral-regurgitation-a-transoesophageal-3d-colour-doppler-analysis-in-500-patients
#2
Björn Goebel, Roland Heck, Ali Hamadanchi, Sylvia Otto, Torsten Doenst, Christian Jung, Alexander Lauten, Hans R Figulla, P Christian Schulze, Tudor C Poerner
Aims: Vena contracta area (VCA3D), derived by 3D colour Doppler echocardiography, has already been validated against cardiac magnetic resonance imaging, but the number of clinical studies to define cut-off values for grading of mitral regurgitation (MR) is limited. Aim of the study was to assess VCA3D in a large population of patients with functional (FMR) and degenerative MR (DMR). Methods and results: Transoesophageal echocardiography was performed in 500 patients with MR...
April 21, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28423126/chronic-atrial-fibrillation-ablation-with-harmonic-scalpel-during-mitral-valve-surgery
#3
Alexandre Visconti Brick, Domingo M Braile
Objective: To evaluate surgical treatment of chronic atrial fibrillation with ultrasound in patients with mitral valve disease, considering preoperative clinical characteristics of patients undergoing surgical procedure and follow-up in the immediate postoperative period, in hospital and up to 60 months after discharge. Methods: We studied 100 patients with chronic atrial fibrillation and mitral valve disease who underwent surgical treatment using ultrasound ablation...
January 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28415104/p697new-indices-for-a-best-quantification-of-left-ventricular-function-in-heart-valve-diseases
#4
A Hubert, E Galli, G Bouzille, E Samset, E Donal
Aims. The Assessment of left ventricular (LV) function remains a clinical challenge especially in patients with preserved LV ejection fraction (EF) and valvular heart diseases (VHD). Mechanical dispersion is supposed to be a strong predictor of events and, to be related to the extent of fibrosis. Regional cardiac work is a new validated and very promising approach to quantify LV-function. We investigated the differences in mechanical dispersions and global LV work (totW) and wasted work fraction (WWF) in normal subjects and in patients with severe primary mitral regurgitation (MR) and severe aortic stenosis (AS)...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28414667/the-mysterious-case-of-dyspnea
#5
S Saad, N Turaga, J Grant, N Jain
INTRODUCTION: Dehiscence of a mitral valve annuloplasty ring is a rare occurrence that often manifests as mitral regurgitation and heart failure. We present a case of mitral ring dehiscence which was initially unrecognized by standard 2-dimensional transthoracic echocardiography (2D TTE); and 2-dimensional transesophageal echocardiography (2D TEE);. CASE: A 65-year-old woman was referred to Cardiology clinic for evaluation of dyspnea. Her history included tobacco abuse, atrial fibrillation status post pulmonary vein isolation, nonischemic cardiomyopathy, and prior mitral valve repair with annuloplasty ring for rheumatic valvular disease...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28407104/minimally-invasive-or-conventional-edge-to-edge-repair-for-severe-mitral-regurgitation-due-to-bileaflet-prolapse-in-barlow-s-disease-does-the-surgical-approach-have-an-impact-on-the-long-term-results-%C3%A2
#6
Michele De Bonis, Elisabetta Lapenna, Benedetto Del Forno, Stefania Di Sanzo, Andrea Giacomini, Davide Schiavi, Luca Vicentini, Azeem Latib, Alberto Pozzoli, Federico Pappalardo, Giovanni La Canna, Ottavio Alfieri
OBJECTIVES: To evaluate whether the adoption of a right minithoracotomy operative approach had an impact on the long-term results of edge-to-edge (EE) repair compared to conventional sternotomy in patients with Barlow's disease and bileaflet prolapse. METHODS: We assessed the long-term results of 104 patients with Barlow's disease treated with a minimally invasive EE technique. An equal number of patients had a conventional median sternotomy EE repair for the same disease and were used as a control group...
April 11, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28401865/the-effect-of-mitral-valve-surgery-on-ventricular-arrhythmia-in-patients-with-bileaflet-mitral-valve-prolapse
#7
Niyada Naksuk, Faisal F Syed, Chayakrit Krittanawong, Mark J Anderson, Elisa Ebrille, Christopher V DeSimone, Vaibhav R Vaidya, Shiva P Ponamgi, Rakesh M Suri, Michael J Ackerman, Vuyisile T Nkomo, Samuel J Asirvatham, Peter A Noseworthy
BACKGROUND: Bileaflet mitral valve prolapse (biMVP) is associated with frequent ventricular ectopy (VE) and malignant ventricular arrhythmia. We examined the effect of mitral valve (MV) surgery on VE burden in biMVP patients. METHODS: We included 32 consecutive patients undergoing MV surgery for mitral regurgitation secondary to biMVP between 1993 and 2012 at Mayo Clinic who had available pre- and post-operative Holter monitoring data. Characteristics of patients with a significant reduction in postoperative VE (group A, defined as >10% reduction in VE burden compared to baseline) were compared with the rest of study patients (group B)...
November 2016: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/28398019/epidemiology-anatomy-pathophysiology-and-clinical-evaluation-of-functional-tricuspid-regurgitation
#8
Yee-Ping Sun, Patrick T O' Gara
Tricuspid regurgitation (TR) is commonly encountered in the management of patients with a variety of cardiovascular diseases. Primary TR is the result of structural abnormalities of the valve or chordal attachments whereas functional TR results from alterations in right ventricular (RV) or right atrial (RA) size, shape or function. The vast majority of TR cases seen in practice are functional in nature and usually results from left-sided heart disease (e.g., mitral valve disease, left ventricular (LV) systolic dysfunction) and/or pulmonary vascular disease, though it also manifests in the presence of isolated chronic atrial fibrillation (AF)...
April 10, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28396198/left-ventricular-access-point-determination-for-a-coaxial-approach-to-the-mitral-annular-landing-zone-in-transcatheter-mitral-valve-replacement
#9
Philipp Blanke, Jong K Park, Paul Grayburn, Christopher Naoum, Kevin Ong, Keshav Kohli, Bjarne L Norgaard, John G Webb, Jeffrey Popma, David Boshell, Paul Sorajja, David Muller, Jonathon Leipsic
INTRODUCTION: To facilitate coaxial device deployment in transcatheter mitral valve replacement (TMVR), a coaxial approach to the mitral annular plane is needed. We sought to establish a method to determine an 'orthogonal' left ventricular (LV) access point for transapical TMVR and to quantitatively characterize its location in patients with severe mitral regurgitation using cardiac computed tomography. METHODS: Cardiac CT data sets of 54 patients with moderate-severe mitral regurgitation evaluated for potential TMVR were analyzed...
April 7, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28386460/reversal-of-abnormal-cardiac-parameters-following-mitral-valve-replacement-for-severe-mitral-stenosis-in-relation-to-pulmonary-artery-pressure-a-retrospective-study-of-noninvasive-parameters-early-and-late-pattern
#10
REVIEW
Usha T Parvathy, Rajesh Rajan, Alexander Georgevich Faybushevich
BACKGROUND AND OBJECTIVES: Although the regression of pulmonary hypertension (PH) in mitral stenosis (MS) has been studied over varying periods postintervention, corresponding studies on the cardiac chamber alterations after surgery are very limited. We sought to determine the degree of reversal of these and the clinical status in connection with that of pulmonary artery pressures (PAPs) in the early and late postoperative periods. METHODS: The preoperative, early, and 1-year postoperative data - functional class (FC), cardiothoracic ratio (CTR) in chest X-ray (CXR), and echocardiographically left atrium (LA), right atrium (RA), right ventricle (RV), left ventricle (LV), and pulmonary artery (PA) dimensions, PAP, tricuspid regurgitation (TR) - of 50 patients who had mitral valve replacement (MVR) for MS with PH were retrospectively analyzed for correlations with PAP (Pearson's), and their change (t-test), in relation to that in PAP...
June 1, 2016: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28384909/immediate-outcome-of-balloon-mitral-valvuloplasty-with-jomiva-balloon-during-pregnancy
#11
Shanmuga Sundaram Rathakrisnnan, Ramona Ramasamy, Tamilarasu Kaliappan, Rajendiran Gopalan, Ramasmy Palanimuthu, Premkrishna Anandhan
INTRODUCTION: Rheumatic mitral stenosis is the most common Valvular Heart Disease encountered during pregnancy. Balloon Mitral Valvuloplasty (BMV) is one of the treatment option available if the symptoms are refractory to the medical management and the valve anatomy is suitable for balloon dilatation. BMV with Inoue balloon is the most common technique being followed worldwide. Over the wire BMV is a modified technique using Joseph Mitral Valvuloplasty (JOMIVA) balloon catheter which is being followed in certain centres...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28380633/corrigendum-to-optimal-results-immediately-after-mitraclip-therapy-or-surgical-edge-to-edge-repair-for-functional-mitral-regurgitation-are-they-really-stable-at-4-years-eur-j-cardiothorac-surg-2016-50-488-494-%C3%A2
#12
Michele De Bonis, Elisabetta Lapenna, Nicola Buzzatti, Giovanni La Canna, Paolo Denti, Federico Pappalardo, Davide Schiavi, Alberto Pozzoli, Micaela Cioni, Giovanna Di Giannuario, Ottavio Alfieri
No abstract text is available yet for this article.
April 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28370497/cardiac-pathophysiology-in-twin-twin-transfusion-syndrome-new-insights-into-its-evolution
#13
Christoph Wohlmuth, David Boudreaux, Kenneth J Moise, Anthony Johnson, Ramesha Papanna, Michael Bebbington, Helena M Gardiner
OBJECTIVES: In twin-twin transfusion syndrome (TTTS) unbalanced transfer of vasoactive mediators and fluid from the 'donor' to the 'recipient' alters cardiovascular function. We evaluated cardiac function in 145 monochorionic-diamniotic (MCDA) pregnancies with and without TTTS. METHODS: Echocardiography was performed in uncomplicated MCDA, n = 26; TTTS stage I+II, n = 61; TTTS stage III+IV, n = 58, before selective fetoscopic laser photocoagulation (SFLP) in TTTS, and afterwards in 41 (34%) at a mean of 1...
March 31, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28364394/transcatheter-mitral-valve-interventions-current-therapies-and-future-directions
#14
REVIEW
Ramon A Partida, Sammy Elmariah
Transcatheter interventions for the treatment of aortic valve stenosis have become commonplace since the advent of transcatheter aortic valve implantation. However, transcatheter mitral valve therapies have lagged in development due to the complexity of mitral valve anatomy. Transcatheter edge-to-edge leaflet repair using the MitraClip device provides an option for the treatment of severe primary mitral valve regurgitation in high or prohibitive surgical risk patients, and multiple novel approaches are evolving to replace or repair the mitral valve...
May 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28360228/echocardiographic-pulmonary-artery-systolic-pressure-in-the-coronary-artery-risk-development-in-young-adults-cardia-study-associations-with-race-and-metabolic-dysregulation
#15
Evan L Brittain, Chike Nwabuo, Meng Xu, Deepak K Gupta, Anna R Hemnes, Henrique T Moreira, Henrique Doria De Vasconcellos, James G Terry, Jeffrey J Carr, Joao A C Lima
BACKGROUND: The determinants of pulmonary artery systolic pressure (PASP) are not fully understood. It is unknown whether racial differences in PASP exist or if other population characteristics are associated with pulmonary pressure in humans. We examined echocardiographically estimated PASP in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a middle-aged, biracial community-based cohort. METHODS AND RESULTS: At the CARDIA year-25 examination, 3469 participants underwent echocardiography, including measurement of tricuspid regurgitant jet velocity to estimate PASP...
March 30, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28357714/the-role-for-cardiovascular-remodeling-in-cardiovascular-outcomes
#16
REVIEW
Nishant Krishna Sekaran, Anna Lisa Crowley, Fernanda Rodrigues de Souza, Elmiro Santos Resende, Sunil V Rao
PURPOSE OF REVIEW: Ischemic and non-ischemic injury to the heart causes deleterious changes in ventricular size, shape, and function. This adverse remodeling is mediated by neurohormonal and hemodynamic alterations and is reflected in non-invasive measures of left ventricular ejection fraction (LVEF), left ventricular end-systolic volume (LVESV), and left ventricular end-diastolic volume (LVEDV). These measures are closely linked to cardiovascular outcomes and have become key surrogate endpoints for evaluating the therapeutic efficacy of contemporary treatments for heart failure with reduced ejection fraction (HFrEF)...
May 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28336789/percutaneous-therapy-for-tricuspid-regurgitation-a-new-frontier-for-interventional-cardiology
#17
Samir R Kapadia, Amar Krishnaswamy, E Murat Tuzcu
Functional tricuspid regurgitation (FTR) is common, whether in association with mitral or aortic valve disease or presenting as an isolated valvular disease. Several studies have shown that TR is associated with poor patient outcomes, though a cause-and-effect relationship of TR to mortality has not been proven. Similarly the impact of surgical treatment of TR on outcomes needs well-controlled randomized trials that are under planning. The current professional society guidelines for treatment of TR are based on expert opinions with a level of evidence C for all indications...
March 23, 2017: Circulation
https://www.readbyqxmd.com/read/28336788/transcatheter-treatment-of-severe-tricuspid-regurgitation-with-the-edge-to-edge-mitraclip-technique
#18
Georg Nickenig, Marek Kowalski, Jörg Hausleiter, Daniel Braun, Joachim Schofer, Ermela Yzeiraj, Volker Rudolph, Kai Friedrichs, Francesco Maisano, Maurizio Taramasso, Neil P Fam, Giovanni Bianchi, Francesco Bedogni, Paolo Denti, Ottavio Alfieri, Azeem Latib, Antonio Colombo, Christoph Hammerstingl, Robert Schueler
Background -Current surgical and medical treatment options for severe tricuspid regurgitation (TR) are limited and additional interventional approaches are required. In the present observational study, the safety and feasibility of transcatheter repair of chronic severe TR with the MitraClip system were evaluated. In addition, the effects on clinical symptoms were assessed. Methods -Patients with heart failure symptoms and severe TR on optimal medical treatment were treated with the MitraClip system. Safety, defined as periprocedural adverse events such as death, myocardial infarction, stroke, or cardiac tamponade, and feasibility, defined as successful implantation of one or more MitraClip devices and reduction of TR by at least one grade, were evaluated before discharge and after 30 days...
March 23, 2017: Circulation
https://www.readbyqxmd.com/read/28335898/mitral-loop-cerclage-encircling-functional-mitral-regurgitation
#19
EDITORIAL
Jason H Rogers
No abstract text is available yet for this article.
March 27, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28331157/the-usefulness-of-combined-assessment-of-e-e-ratio-and-transmitral-flow-pattern-to-interpret-cardiac-condition
#20
Masayoshi Oikawa, Atsushi Kobayashi, Takamasa Sato, Satoshi Suzuki, Yoshihisa Akiomi, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Yasuchika Takeishi
High mitral inflow early (E) velocity to tissue Doppler E' ratio (E/E') and an E to late diastolic filling velocity ratio (E/A) are used to evaluate left ventricular (LV) diastolic function and filling pressure, but the usefulness of combined assessment of E/E' and E/A is not fully understood. Methods: We retrospectively analyzed 1,266 patients who underwent echocardiography to assess cardiac function. Patients were grouped based on the values of E/E' (low E/E'<15, high E/E'≥15) and E/A (low E/A≤0...
March 22, 2017: Fukushima Journal of Medical Science
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