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functional mitral regurgitation

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https://www.readbyqxmd.com/read/28209176/infective-endocarditis-causing-mitral-valve-stenosis-a-rare-but-deadly-complication-a-case-report
#1
Michael A Hart, Gautam R Shroff
BACKGROUND: Infective endocarditis rarely causes mitral valve stenosis. When present, it has the potential to cause severe hemodynamic decompensation and death. There are only 15 reported cases in the literature of mitral prosthetic valve bacterial endocarditis causing stenosis by obstruction. This case is even more unusual due to the mechanism by which functional mitral stenosis occurred. CASE PRESENTATION: We report a case of a 23-year-old white woman with a history of intravenous drug abuse who presented with acute heart failure...
February 17, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28190605/the-importance-of-age-and-weight-on-cavopulmonary-shunt-stage-ii-outcomes-after-the-norwood-procedure-planned-versus-unplanned-surgery
#2
David J Barron, Intisar Ul Haq, Adrian Crucean, John Stickley, Phil Botha, Natasha Khan, Timothy J Jones, William J Brawn
OBJECTIVE: The study objective was to evaluate the outcomes of the cavopulmonary shunt after the Norwood procedure with a particular focus on age, weight, and whether surgery was planned or expedited by clinical findings. METHODS: We studied 297 consecutive patients with hypoplastic left heart syndrome undergoing the cavopulmonary shunt operation between 2002 and 2014. All patients underwent the Norwood procedure with a right ventricle to pulmonary artery conduit...
January 17, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28169216/prognostic-implication-of-post-mitraclip-vena-contracta-area-in-heart-failure-patients-with-functional-mitral-regurgitation
#3
Hannes Alessandrini, Felix Kreidel, Michael Schlüter, Christian Frerker, Tobias Schmidt, Thomas Thielsen, Ulrich Schäfer, Karl-Heinz Kuck
AIMS: Significant functional mitral regurgitation (FMR) in elderly heart-failure patients is increasingly being treated by MitraClip implantation. We sought to assess the prognostic implications of the intraprocedural assessment of vena contracta area (VCA) after MitraClip therapy in such patients. METHODS AND RESULTS: MitraClip therapy with intraprocedural assessment of VCA was performed in 97 heart-failure patients (74±10 years; 66 men; left ventricular ejection fraction [LVEF] 31±12%; 93 patients in New York Heart Association [NYHA] functional class III [n=59] or IV [n=34]; 86 patients with FMR severity 3+ [n=65] or 4+ [n=21])...
February 8, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28168077/a-case-of-neonatal-marfan-syndrome-a-management-conundrum-and-the-role-of-a-multidisciplinary-team
#4
Elliott J Carande, Samuel J Bilton, Satish Adwani
Neonatal Marfan syndrome (nMFS) is a rare condition with a poor prognosis. It is genotypically and phenotypically distinct from the typical Marfan syndrome and carries a poorer prognosis. This case report describes the progression of a 14-month-old girl diagnosed with nMFS at 5 months of age. Her diagnosis followed the identification of a fibrillin-1 mutation (FBN1 gene, exon 26, chromosome 15), which is a common locus of nMFS. This patient developed severe cardiac complications resulting in congestive cardiac failure in early life and required major cardiac surgery...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28163835/one-year-outcome-of-percutaneous-mitral-valve-repair-in-patients-with-severe-symptomatic-mitral-valve-regurgitation
#5
Michael Gotzmann, Isabell Sprenger, Aydan Ewers, Andreas Mügge, Leif Bösche
AIM: To investigate one-year outcomes after percutaneous mitral valve repair with MitraClip(®) in patients with severe mitral regurgitation (MR). METHODS Our study investigated consecutive patients with symptomatic severe MR who underwent MitraClip(®) implantation at the University Hospital Bergmannsheil from 2012 to 2014. The primary study end-point was all-cause mortality. Secondary end-points were degree of MR and functional status after percutaneous mitral valve repair. RESULTS: The study population consisted of 46 consecutive patients (mean logistic EuroSCORE 32% ± 21%)...
January 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28149574/ischemic-mitral-valve-prolapse
#6
REVIEW
Francesco Nappi, Spadaccio Cristiano, Antonio Nenna, Massimo Chello
Ischemic mitral prolapse (IMP) is a pathologic entity encountered in about one-third among the patients undergoing surgery for ischemic mitral regurgitation (IMR). IMP is generally the result of a papillary muscle injury consequent to myocardial, but the recent literature is progressively unveiling a more complex pathogenesis. The mechanisms underlying its development regards the impairment of one or more components of the mitral apparatus, which comprises the annulus, the chordae tendineae, the papillary muscle and the left ventricular wall...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28145607/left-atrial-strain-at-different-stages-of-myxomatous-mitral-valve-disease-in-dogs
#7
K Nakamura, S Kawamoto, T Osuga, T Morita, N Sasaki, K Morishita, H Ohta, M Takiguchi
BACKGROUND: Decreased function of the left atrium (LA) is a useful prognostic indicator in dogs with myxomatous mitral valve disease (MMVD). In humans, LA strain is a novel severity indicator of mitral regurgitation, but its clinical utility in dogs has not been confirmed. OBJECTIVES: To examine whether LA strain as evaluated with speckle-tracking echocardiography is associated with MMVD stage in dogs. ANIMALS: Fifty-two client-owned dogs with MMVD...
February 1, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28144714/-new-and-established-aspects-of-cardiological-diagnostics-using-tee-do-we-need-3d-technology-in-clinical-routine
#8
A Hagendorff, S Stoebe, D Jurisch, M Neef, M Metze, D Pfeiffer
In comparison to transthoracic echocardiography (TTE) transesophageal echocardiography (TEE) enables an acquisition of images with better spatial resolution due to the use of higher ultrasound frequencies. Thus, the morphology and function of cardiac structures can principally be analyzed better and more accurately with TEE than with TTE. In addition, using three-dimensional (3D) TEE data sets standardized sectional planes can be constructed by post-processing, which enables quantitative assessment of the target structures...
January 31, 2017: Herz
https://www.readbyqxmd.com/read/28140523/tissue-plasminogen-activator-for-neonatal-coronary-thrombosis-presenting-with-mitral-valve-regurgitation-and-impaired-ventricular-function
#9
Delaram Molkara, Jose A Silva Sepulveda, Thomas Do, Christopher Davis, Gregory P Goldstein, John W Moore, Howaida G El-Said
OBJECTIVE: Neonatal coronary thrombosis is a rarely reported disorder, with variable outcomes described. This study assessed the feasibility and safety of an institutional protocol using tissue plasminogen activator (tPA) administration for the treatment of neonatal coronary artery thrombi. METHODS: They reviewed the outcome of three neonates with clinical evidence of myocardial infarction secondary to coronary thrombosis. All three underwent the tPA treatment protocol...
January 31, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28130861/an-assessment-of-left-atrial-function-in-patients-with-hypertrophic-obstructive-cardiomyopathy-before-and-1%C3%A2-year-after-septal-ablation-by-two-dimensional-speckle-tracking-echocardiography
#10
Hui Fang, Hailin Tang, Peng Li, Li Xiong, Gongpai Hu, Li Li, Yonghong Yu, Bowen Zhao
OBJECTIVE: The objective of this study was to assess left atrial (LA) function with two-dimensional speckle tracking echocardiography (2DSTE) in addition to standard echocardiographic assessments in patients with hypertrophic obstructive cardiomyopathy (HOCM) before and 1 year after septal ablation (SA). METHODS: The study included 31 patients with HOCM, who underwent SA. Each patient with HOCM underwent a complete two-dimensional transthoracic echocardiography before and 1 year after the SA...
January 28, 2017: Echocardiography
https://www.readbyqxmd.com/read/28130803/mitral-annular-motion-in-patients-after-transcatheter-mitraclip-and-mitral-valve-surgery
#11
Kentaro Toyama, Florian Rader, Kengo Ayabe, Saibal Kar, Alfredo Trento, Toshihiko Nishioka, Michele A De Robertis, Robert J Siegel
BACKGROUND: Longitudinal motion of the mitral annulus is an index that reflects left ventricular (LV) function. The aim of this study was to evaluate and compare the effects of transcatheter mitral valve (MV) repair and open heart surgery for mitral regurgitation (MR) on mitral annular motion (MAM). METHODS: We retrospectively analyzed in total 115 patients who underwent isolated transcatheter MV repair using MitraClip (n=50) or surgical MV interventions (n=65, 50 repairs and 15 replacements) for MR...
January 28, 2017: Echocardiography
https://www.readbyqxmd.com/read/28130793/twist-deformation-for-predicting-postoperative-left-ventricular-function-in-patients-with-mitral-regurgitation-a-speckle-tracking-echocardiography-study
#12
Ozkan Candan, Suzan Hatipoglu Akpinar, Cem Dogan, Aykut Demirkıran, Barış Dindar, Zubeyde Bayram, Fatih Yılmaz, Cihangir Kaymaz, Nihal Ozdemir
PURPOSE: Postoperative LV dysfunction is associated with poor prognosis and increased mortality in patient with mitral regurgitation undergoing surgery. With this study, we aimed to investigate the predictive value of classic and speckle tracking echocardiographic (STE) LV deformational parameters for estimating postoperative LV dysfunction. METHODS: Fifty-nine asymptomatic patients with severe mitral regurgitation (MR) due to mitral valve prolapse, who had sinus rhythm and LV ejection fraction (EF) ≥50%, were included...
January 28, 2017: Echocardiography
https://www.readbyqxmd.com/read/28127033/advanced-imaging-in-valvular-heart-disease
#13
REVIEW
Jeroen J Bax, Victoria Delgado
Although echocardiography remains the mainstay imaging technique for the evaluation of patients with valvular heart disease (VHD), innovations in noninvasive imaging in the past few years have provided new insights into the pathophysiology and quantification of VHD, early detection of left ventricular (LV) dysfunction, and advanced prognostic assessment. The severity grading of valve dysfunction has been refined with the use of Doppler echocardiography, cardiac magnetic resonance (CMR), and CT imaging. LV ejection fraction remains an important criterion when deciding whether patients should be referred for surgery...
January 27, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28126390/prognostic-implications-of-functional-mitral-regurgitation-in-patients-with-heart-failure-and-reduced-ejection-fraction
#14
M Dolores García-Cosío Carmena, Eulalia Roig Minguell, Andreu Ferrero-Gregori, Rafael Vázquez García, Juan Delgado Jiménez, Juan Cinca
No abstract text is available yet for this article.
January 23, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28119045/cardiac-resynchronization-therapy-before-and-after-mitraclip-implantation-an-advantageous-upgrading-to-reduce-mitral-regurgitation
#15
Francesco Versaci, Giampiero Vizzari, Domenico Sergi, Antonio Trivisonno, Giuseppe Andò, Stefano Nardi, Gian Paolo Ussia, Francesco Romeo
MitraClip therapy has been proposed as therapeutic option in selected patients with degenerative or functional mitral regurgitation (FMR), leading to clinical and prognostic benefits. Previous studies demonstrated the safety and the efficacy of MitraClip therapy on symptoms and left ventricular remodeling in cardiac resynchronization therapy (CRT) non-responder patients. We report a case of a CRT non-responder patient treated with MitraClip implantation followed by a new upgrading of the CRT for persistent FMR at the follow-up...
January 17, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28117279/first-percutaneous-micra-leadless-pacemaker-implantation-and-tricuspid-valve-repair-with-mitraclip-nt-for-lead-associated-severe-tricuspid-regurgitation
#16
Gilbert H L Tang, Ryan Kaple, Martin Cohen, Tanya Dutta, Cenap Undemir, Hasan Ahmad, Angelica Poniros, Joanne Bennett, Cheng Feng, Steven Lansman
AIMS: Pacemaker lead-associated severe tricuspid regurgitation (TR) can lead to right heart failure and poor prognosis. Surgery in these patients carries significant morbidities. We describe a successful treatment of symptomatic severe TR by leadless pacemaker implantation followed by tricuspid valve (TV) repair with the MitraClip NT. METHODS AND RESULTS: A 71-year-old frail female with poor functional status, chronic atrial fibrillation and permanent pacemaker implantation in 2012 presented with symptomatic moderate-severe mitral regurgitation (MR) and severe TR with the pacemaker lead as the culprit...
February 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28112459/deep-sedation-vs-general-anesthesia-in-232-patients-undergoing-percutaneous-mitral-valve-repair-using-the-mitraclip-%C3%A2-system
#17
Patrick Horn, Katharina Hellhammer, Michael Minier, Monika A Stenzel, Verena Veulemans, Tienush Rassaf, Peter Luedike, Julia Pohl, Jan Balzer, Tobias Zeus, Malte Kelm, Ralf Westenfeld
OBJECTIVES: To investigate in a series of 232 patients whether the MitraClip(®) procedure can be performed safely using deep sedation (DS) without general anesthesia (GA). BACKGROUND: Transcatheter mitral valve repair using the MitraClip(®) system is a safe and effective therapy for severe mitral regurgitation (MR) in patients who are at high operative risk or are unsuitable for surgery. For these patients, avoidance of GA might be beneficial. METHODS: Between 2011 and 2015, we performed 232 MitraClip(®) procedures for the treatment of severe MR...
January 23, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28109559/meta-analysis-of-usefulness-of-concomitant-mitral-valve-repair-or-replacement-for-moderate-ischemic-mitral-regurgitation-with-coronary-artery-bypass-grafting
#18
Salah E Altarabsheh, Salil V Deo, Shannon M Dunlay, Patricia J Erwin, Yagthan M Obeidat, Suparna Navale, Alan H Markowitz, Soon J Park
Moderate ischemic mitral regurgitation (MR) is often present in patients undergoing coronary artery bypass grafting (CABG). However, the clinical benefit of repairing moderate MR during CABG is unproven. We searched multiple databases to identify original studies comparing isolated CABG versus combined CABG and MR surgery (mitral valve surgery with coronary artery bypass grafting [MVCABG]); survival (either early or midterm) was the primary end point. Risk ratio (RR) or standardize mean difference was selected as the effect estimates; survival was compared by pooling hazard ratios...
December 9, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28109210/surgical-repair-of-moderate-ischemic-mitral-regurgitation-a-systematic-review-and-meta-analysis
#19
Mahesh Anantha Narayanan, Saurabh Aggarwal, Yogesh N V Reddy, Venkata M Alla, Janani Baskaran, Arun Kanmanthareddy, Rakesh M Suri
Introduction Moderate mitral regurgitation (MR) of ischemic etiology has been associated with worse outcomes after coronary artery bypass grafting (CABG). Studies comparing concomitant mitral valve replacement/repair (MVR/Re) with CABG and standalone CABG have reported conflicting results. We performed a systematic review and meta-analysis of the published literature. Patients and Methods We searched using PubMed, Cochrane, EMBASE, CINAHL, and Google scholar databases from January 1960 to June 2016 for clinical trials comparing CABG to CABG + MVR/Re for moderate MR...
January 21, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28109132/echocardiographic-assessment-of-left-ventricular-function-in-healthy-horses-and-in-horses-with-heart-disease-using-pulsed-wave-tissue-doppler-imaging
#20
T R Koenig, K J Mitchell, C C Schwarzwald
BACKGROUND: Assessment of left ventricular (LV) function by tissue Doppler imaging (TDI) is not well established in horses with heart disease. OBJECTIVES: To describe the use of pulsed-wave (PW) TDI for the assessment of LV function, establish reference intervals, investigate effects of mitral regurgitation (MR), aortic regurgitation (AR), and primary myocardial disease (MD), and provide proof of concept for the use of PW TDI in Warmblood horses with heart disease...
January 21, 2017: Journal of Veterinary Internal Medicine
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