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https://www.readbyqxmd.com/read/28738925/complicated-mammoplasty-and-breast-salvage-with-application-of-extracellular-matrix
#1
Amanda L Swickard, Jason D Sciarretta
No abstract text is available yet for this article.
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28713712/management-of-gigantomastia-outcomes-of-superomedial-pedicle-with-vertical-scar-or-wise-pattern-skin-excision
#2
Mehmet Can Sak, Selcuk Akın, Burak Ersen, Orhan Tunalı, Aksu Ismail
BACKGROUND: Gigantomastia is a rare condition characterized by excessive breast growth and can be physically and psychosocially disabling for the patient. Regarding management of gigantomastia, this study evaluates the outcomes of superomedial pedicle with vertical scar or wise pattern skin excision. METHODS: A total of 425 patients who underwent reduction mammoplasty in our institution were reviewed. Forty eight reduction mammoplasty patients with resection weights greater than 1 kg per breast and treated with superomedial dermoglandular pedicle technique combined with vertical or wise-pattern skin excision were included...
May 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28708432/epigenetic-changes-of-the-esr1-gene-in-breast-tissue-of-healthy-women-a-missing-link-with-breast-cancer-risk-factors
#3
Abdolreza Daraei, Pantea Izadi, Ghasemali Khorasani, Nahid Nafissi, Mohammad Mehdi Naghizadeh, Nasim Younosi, Alipasha Meysamie, Yaser Mansoori, Milad Bastami, Javad Tavakkoly-Bazzaz
BACKGROUND: Reproductive history and obesity are among the well-recognized risk factors in the development of breast cancer, which are partially mediated by the increased exposure of breast tissues to estrogens. However, only a few studies have investigated the link between these risk factors and the pattern of methylation signatures in the breast tissue of healthy women. The role of estrogen receptor 1 (ESR1) gene hypermethylation is reportedly important in the development of breast cancer...
July 14, 2017: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/28698934/combination-of-w%C3%A3-ringer-s-horizontal-septum-and-inferior-pedicle-techniques-to-increase-nipple-areolar-complex-viability-during-breast-reduction-surgery
#4
Osman Kelahmetoglu, Remzi Firinciogullari, Caglayan Yagmur, Kemalettin Yildiz, Ethem Guneren
BACKGROUND: Breast reduction techniques depend on the vascularity of the pedicle. Preserving vascularity of the nipple-areolar complex (NAC) is mandatory for reduction mammoplasties, as the NAC is the most important aesthetic and functional unit of the breast. The inferior pedicle technique is the most common method for breast reduction; however, pedicle length may increase after using this technique and cause problems related to NAC viability in gigantomastic and hypertrophic breasts...
July 11, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28670334/evaluation-of-human-cytomegalovirus-antigen-expression-in-invasive-breast-carcinoma-in-a-population-of-iranian-patients
#5
Fereshteh Mohammadizadeh, Fatemeh Mahmudi
BACKGROUND: The role of human cytomegalovirus (HCMV) in the development of breast carcinoma is questionable. The aim of this study was to evaluate the expression of the immediate early antigen (IE) of HCMV in breast carcinoma and its association with some clinicopathologic factors in a population of Iranian patients. METHODS: Formalin-fixed and paraffin-embedded tissue blocks from the pathology laboratories of the Azahra and Shahid Beheshti hospitals, Isfahan, Iran, from 2013 to 2016, were used in the study...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28632641/letter-to-prs-editor-comparing-round-and-anatomically-shaped-implants-in-augmentation-mammoplasty-the-experts-ability-to-differentiate-the-type-of-implant
#6
Carlos G Rubi, Jose Angel Lozano, Alberto Pérez-Espadero, Elena Leache
No abstract text is available yet for this article.
June 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28632639/letter-to-prs-editor-re-comparing-round-and-anatomically-shaped-implants-in-augmentation-mammoplasty-the-experts-ability-to-differentiate-the-type-of-implant
#7
Carlos G Rubi, Elena Leache, Jose Angel Lozano, Alberto Pérez-Espadero
No abstract text is available yet for this article.
June 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28632636/letter-to-prs-editor-re-comparing-round-and-anatomically-shaped-implants-in-augmentation-mammoplasty-the-experts-ability-to-differentiate-the-type-of-implant
#8
Carlos G Rubi, Elena Leache, Jose Angel Lozano, Alberto Pérez-Espadero
No abstract text is available yet for this article.
June 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28615534/functional-dissection-of-breast-cancer-risk-associated-tert-promoter-variants
#9
Sonja Helbig, Leesa Wockner, Annick Bouendeu, Ursula Hille-Betz, Karen McCue, Juliet D French, Stacey L Edwards, Hilda A Pickett, Roger R Reddel, Georgia Chenevix-Trench, Thilo Dörk, Jonathan Beesley
The multi-cancer susceptibility locus at 5p15.33 includes TERT, encoding the telomerase catalytic subunit. Genome-wide association studies (GWAS) have identified six single nucleotide polymorphisms (SNPs) in the TERT promoter associated with decreased breast cancer risk, although the precise causal variants and their mechanisms of action have remained elusive. Luciferase reporter assays indicated that the protective haplotype reduced TERT promoter activity in human mammary epithelial and cancer cells in an estrogen-independent manner...
May 26, 2017: Oncotarget
https://www.readbyqxmd.com/read/28610472/incidental-breast-carcinoma-in-reduction-mammoplasty
#10
Michaël Huysmans, Marc Bronckaers, Charlotte Schillebeeckx, Dirk Servaes
AIM: The objective of this study was to analyze the incidence and treatment options of occult cancer or atypical lesions found in the histopathological examination of reduction mammoplasty (RM) specimens. The role of preoperative mammography and systematic histopathological examination are discussed. METHODS: We performed a retrospective single-center database review of all patients who underwent a RM between January 2005 and December 2014. Preoperative examination, histopathological findings and follow-up were documented...
June 13, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28598828/gigantomastia-due-to-retromammary-lipoma-an-aesthetic-management
#11
Sandipan Gupta, Debarati Chattopadhyay, Souradip Gupta, Akhilesh Agarwal, Gautam Guha
INTRODUCTION: A "giant" lipoma is defined as a tumor having dimensions greater than 10 cm. Giant lipomas are rare and giant breast lipomas are exceptionally uncommon. Only six cases have been described in world literature till date. Herein we describe a case of giant breast lipoma and discuss its surgical management. CASE REPORT: A 43-year-old lady presented with left sided unilateral gigantomastia. Clinical examination, radiology and histopathology diagnosed lipoma...
June 2, 2017: Breast Disease
https://www.readbyqxmd.com/read/28582838/the-effect-of-gigantomasty-on-vertebral-degeneration-a-computed-tomography-study
#12
Bekir Sanal, Mehmet Korkmaz, Omer Fatih Nas, Fatma Can, Kadir Hacikurt
The main reason for waist and back pain in patients with gigantomasty is increased thoracic kyphosis and lumber lordosis. These symptoms and abnormal spinal angulations regress after reduction mammoplasty operations. However, the effect of chronic mechanical stress caused by gigantomasty on the spinal degenerative process is not clear yet. In this study with computed tomography it is shown that degenerative spondylosis is more widespread and severe in patients with large breasts.
May 12, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28578506/first-international-consensus-conference-on-standardization-of-oncoplastic-breast-conserving-surgery
#13
Walter P Weber, Savas D Soysal, Mahmoud El-Tamer, Virgilio Sacchini, Michael Knauer, Christoph Tausch, Nik Hauser, Andreas Günthert, Yves Harder, Elisabeth A Kappos, Fabienne Schwab, Florian Fitzal, Peter Dubsky, Vesna Bjelic-Radisic, Roland Reitsamer, Rupert Koller, Jörg Heil, Markus Hahn, Jens-Uwe Blohmer, Jürgen Hoffmann, Christine Solbach, Christoph Heitmann, Bernd Gerber, Martin Haug, Christian Kurzeder
PURPOSE: To obtain consensus recommendations for the standardization of oncoplastic breast conserving surgery (OPS) from an international panel of experts in breast surgery including delegates from the German, Austrian and Swiss societies of senology. METHODS: A total of 52 questions were addressed by electronic voting. The panel's recommendations were put into context with current evidence and the report was circled in an iterative open email process until consensus was obtained...
June 3, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28570465/shared-medical-appointments-for-adolescent-breast-reduction
#14
Tara L Braun, Matthew G Kaufman, Cristina Hernandez, Laura A Monson
Adolescents with macromastia face serious physical, emotional, and social burdens because of their large breast size. Studies have shown that reduction mammoplasty results in improvement in physical symptoms and quality of life for these patients. Shared medical appointments (SMAs), defined as individual patient-physician encounters that occur in a group setting, have been successfully applied to clinics for adult patients seeking breast reduction for this condition. We decided to apply the SMA model to our clinic for preoperative evaluation of adolescent patients with macromastia...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28570457/reviewing-the-evidence-to-guide-clinical-care-proliferative-breast-lesions-in-breast-reduction-specimens
#15
Rachel M Akintayo, Kari M Rosenkranz, Wendy A Wells, Emily B Ridgway
The number of reduction mammoplasties performed in the United States continues to increase annually. Given the high incidence of breast cancer in women, it is routine practice for breast tissue excised during routine breast reductions procedures to be sent for pathology review. During pathology assessment, occult malignancy and on-occasion proliferative breast lesions of unknown and/or variable malignancy may also be present. We provide a review of commonly diagnosed atypical proliferative breast lesions in breast reduction specimens and a guide to plastic surgeons for further management...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28542075/examining-the-role-of-antimicrobial-irrigation-and-capsular-contracture-a-systematic-review-and-meta-analysis
#16
James J Drinane, Tayseer Chowdhry, Thuy-Huong Pham, Edmond Ritter
PURPOSE: The purpose of this study was to conduct a meta-analysis to determine if irrigation of breast implant pockets with antibiotics reduces the rate of capsular contracture (CC). Capsular contracture is the most common complication after primary augmentation mammoplasty, yet its etiology remains cryptogenic. METHODS: PubMed was searched for publications from January 1 of 2000 through October of 2015. Studies with the following criteria were included: primary breast augmentation with implants, use of antimicrobial irrigation (AMI), and documentation of CC...
July 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28536929/inferior-pedicle-reduction-mammoplasty-with-or-without-tourniquet-a-comparative-study
#17
Canser Yilmaz Demir, Yılmaz Sultanoglu, Omer Faruk Kocak, Muhammet Eren Ersoz
OBJECTIVE: To compare the perioperative findings of inferior pedicle reduction mammoplasty (IPRM) performed with or without a tourniquet. METHODS: This study was carried out in the plastic and reconstructive surgery department at a tertiary care center on a total of 42 consecutive women scheduled for IPRM. Patients in Group I (n = 21) underwent surgery using a tourniquet, whereas patients in Group II (n = 21) were operated on without a tourniquet. Levels of hemoglobin (Hb), hematocrit (Hct), Hct/Hb ratio, and platelet counts were noted preoperatively and on postoperative 24th and 48th h...
May 23, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28448389/long-term-results-after-oncoplastic-surgery-for-breast-cancer-a-10-year-follow-up
#18
Krishna B Clough, Raquel F D van la Parra, Helene H Thygesen, Eric Levy, Elisabeth Russ, Najeeb M Halabi, Isabelle Sarfati, Claude Nos
OBJECTIVE: The aim of this study was to evaluate the long-term oncologic outcome after oncoplastic surgery (OPS). BACKGROUND: OPS combines wide tumor excision with reduction mammoplasty techniques thus extending breast conserving surgery to large tumors that might else be proposed a mastectomy. Little data are available about the oncologic results for breast conserving surgery of these larger tumors. METHODS: From January 2004 until March 2016, a total of 350 oncoplastic breast reductions were prospectively entered into a database...
April 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28444535/image-analysis-of-immune-cell-patterns-in-the-human-mammary-gland-during-the-menstrual-cycle-refines-lymphocytic-lobulitis
#19
Nadine S Schaadt, Juan Carlos López Alfonso, Ralf Schönmeyer, Anne Grote, Germain Forestier, Cédric Wemmert, Nicole Krönke, Mechthild Stoeckelhuber, Hans H Kreipe, Haralampos Hatzikirou, Friedrich Feuerhake
PURPOSE: To improve microscopic evaluation of immune cells relevant in breast cancer oncoimmunology, we aim at distinguishing normal infiltration patterns from lymphocytic lobulitis by advanced image analysis. We consider potential immune cell variations due to the menstrual cycle and oral contraceptives in non-neoplastic mammary gland tissue. METHODS: Lymphocyte and macrophage distributions were analyzed in the anatomical context of the resting mammary gland in immunohistochemically stained digital whole slide images obtained from 53 reduction mammoplasty specimens...
April 25, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28438622/p53-alteration-in-morphologically-normal-benign-breast-luminal-cells-in-brca-carriers-with-or-without-history-of-breast-cancer
#20
Xi Wang, Amber A El-Halaby, Hengwei Zhang, Qi Yang, Todd S Laughlin, Paul G Rothberg, Kristin Skinner, David G Hicks
Germ-line mutations in BRCA genes have been shown to predispose patients to breast cancer. Studies have suggested that p53 alteration is a necessary step in tumorigenesis in BRCA carriers. Our previous study showed p53 alteration in morphologically normal/benign breast luminal cells in sporadic breast cancer patients, the so-called "breast p53 signature". Here, we studied p53 status in 66 BRCA1/2 carriers' breasts; 29 patients with breast carcinoma (2 patients with bilateral breast carcinomas) and 37 without...
April 21, 2017: Human Pathology
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