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https://www.readbyqxmd.com/read/28446627/silicon-alleviates-nonalcoholic-steatohepatitis-by-reducing-apoptosis-in-aged-wistar-rats-fed-a-high-saturated-fat-high-cholesterol-diet
#1
Alba Garcimartín, M Elvira López-Oliva, Jorge A Sántos-López, Rosa A García-Fernández, Adrián Macho-González, Sara Bastida, Juana Benedí, Francisco J Sánchez-Muniz
Background: Lipoapoptosis has been identified as a key event in the progression of nonalcoholic fatty liver disease (NAFLD), and hence, antiapoptotic agents have been recommended as a possible effective treatment for nonalcoholic steatohepatitis (NASH). Silicon, included in meat as a functional ingredient, improves lipoprotein profiles and liver antioxidant defenses in aged rats fed a high-saturated fat, high-cholesterol diet (HSHCD). However, to our knowledge, the antiapoptotic effect of this potential functional meat on the liver has never been tested...
April 26, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28446501/dietary-long-chain-fatty-acids-and-carbohydrate-biomarker-evaluation-in-a-controlled-feeding-study-in-participants-from-the-women-s-health-initiative-cohort
#2
Xiaoling Song, Ying Huang, Marian L Neuhouser, Lesley F Tinker, Mara Z Vitolins, Ross L Prentice, Johanna W Lampe
Background: Biomarkers of macronutrient intake are lacking. Controlled human feeding studies that preserve the normal variation in nutrient and food consumption are necessary for the development and validation of robust nutritional biomarkers.Objective: We aimed to assess the utility of serum phospholipid fatty acids (PLFAs) as biomarkers of dietary intakes of fatty acids, total fat, and carbohydrate.Design: We used an individualized controlled feeding study in which 153 postmenopausal women from the Women's Health Initiative (WHI) were provided with a 2-wk controlled diet that mimicked each individual's habitual food intake...
April 26, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28445914/clinical-significance-of-intraluminal-contrast-enhancement-in-patients-with-spontaneous-cervical-artery-dissection-a%C3%A2-black-blood-mri-study
#3
Eva Coppenrath, Olga Lenz, Nora Sommer, Nina Lummel, Jennifer Linn, Karla Treitl, Fabian Bamberg, Maximilian Reiser, Thomas Pfefferkorn, Tobias Saam
Purpose Recent studies have suggested that intraluminal thrombi show contrast enhancement on carotid black-blood T1w MRI. The aim of this study was to evaluate the significance of intraluminal contrast enhancement (iCE) regarding symptom status in patients with spontaneous cervical artery dissection (sCAD). Methods 33 consecutive patients (19 men) with sCAD received a brain MRI (DIFF, T2w, T2*w, FLAIR) and a multi-sequence 3T-MRI with fat-saturated high-resolution black-blood T1w-sequences pre- and post-contrast, contrast-enhanced MR angiography and TOF images of carotid and vertebral arteries...
April 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28442474/saturated-fat-does-not-clog-the-arteries-coronary-heart-disease-is-a-chronic-inflammatory-condition-the-risk-of-which-can-be-effectively-reduced-from-healthy-lifestyle-interventions
#4
EDITORIAL
Aseem Malhotra, Rita F Redberg, Pascal Meier
No abstract text is available yet for this article.
April 25, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28438715/impact-of-physical-exercise-on-visceral-adipose-tissue-fatty-acid-profile-and-inflammation-in-response-to-a-high-fat-diet-regimen
#5
Sílvia Rocha-Rodrigues, Amaia Rodríguez, Inês O Gonçalves, Ana Moreira, Elisabete Maciel, Sónia Santos, Maria R Domingues, Gema Frühbeck, António Ascensão, José Magalhães
PURPOSE: Studies associate specific fatty-acids (FA) with the pathophysiology of inflammation. We aimed to analyze the impact of exercise on adipose tissue FA profile in response to a high-fat diet (HFD) and to ascertain whether these exercise-induced changes in specific FA have repercussions on obesity-related inflammation. METHODS: Sprague-Dawley rats were assigned into sedentary, voluntary physical-activity (VPA) and endurance training (ET) groups fed a standard (S, 35kcal% fat) or high-fat (71kcal% fat) diets...
April 21, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28438322/water-fat-dixon-sequences-in-the-evaluation-of-breast-implants-proposal-of-a-time-effective-rapid-approach-in-the-clinical-practice
#6
M Marcon, A S Becker, E J Ulbrich, T Frauenfelder, A Boss
AIM: To evaluate the diagnostic accuracy achieved from a fat-water Dixon sequence alone compared to a combination of a silicone-specific magnetic resonance imaging (MRI) sequence and a water-specific MRI sequence in the assessment of breast implants. MATERIALS AND METHODS: In this institutional review board (IRB)-approved study the integrity of breast implants was assessed retrospectively in 27 patients undergoing breast MRI at 3 T. A qualitative evaluation of (set 1) a silicon-selective water-saturated short tau inversion recovery (STIR) sequence in combination with a water-only Dixon dataset (total acquisition time 7 minutes 17 seconds), and of (set 2) fat-only and water-only Dixon datasets (4 minutes 8 seconds) was performed by two readers independently evaluating the following features: margin definition of the implant, water suppression homogeneity, image quality, presence of artefacts and their effects on the imaging interpretation, and diagnostic confidence...
April 21, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28437863/sirt3-acts-as-a-negative-regulator-of-autophagy-dictating-hepatocyte-susceptibility-to-lipotoxicity
#7
Songtao Li, Xiaobing Dou, Hua Ning, Qing Song, Wei Wei, Ximei Zhang, Chen Shen, Jiaxin Li, Changhao Sun, Zhenyuan Song
Lipotoxicity induced by saturated fatty acids (SFAs) plays a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD); however, the exact mechanism(s) remain to be fully elucidated. SIRT3 is an NAD(+) -dependent deacetylase primarily located inside mitochondria. In this study, we demonstrated that a SFAs-rich high-fat diet (HFD) was more detrimental to the liver than an isocaloric unsaturated FAs-rich HFD. Unexpectedly, SIRT3 expression/activity were significantly elevated in the livers of mice exposed to the SFAs-rich HFD...
April 24, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28434733/short-communication-discrimination-between-retail-bovine-milks-with-different-fat-contents-using-chemometrics-and-fatty-acid-profiling
#8
Einar Vargas-Bello-Pérez, Paula Toro-Mujica, Daniel Enriquez-Hidalgo, María Angélica Fellenberg, Pilar Gómez-Cortés
We used a multivariate chemometric approach to differentiate or associate retail bovine milks with different fat contents and non-dairy beverages, using fatty acid profiles and statistical analysis. We collected samples of bovine milk (whole, semi-skim, and skim; n = 62) and non-dairy beverages (n = 27), and we analyzed them using gas-liquid chromatography. Principal component analysis of the fatty acid data yielded 3 significant principal components, which accounted for 72% of the total variance in the data set...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434722/prediction-of-milk-fatty-acid-content-with-mid-infrared-spectroscopy-in-canadian-dairy-cattle-using-differently-distributed-model-development-sets
#9
A Fleming, F S Schenkel, J Chen, F Malchiodi, V Bonfatti, R A Ali, B Mallard, M Corredig, F Miglior
The fatty acid profile of milk is a prevailing issue due to the potential negative or positive effects of different fatty acids to human health and nutrition. Mid-infrared spectroscopy can be used to obtain predictions of otherwise costly fatty acid phenotypes in a widespread and rapid manner. The objective of this study was to evaluate the prediction of fatty acid content for the Canadian dairy cattle population from mid-infrared spectral data and to compare the results produced by altering the partial least squares (PLS) model development set used...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28432403/bone-marrow-fat-content-in-70-adolescent-girls-with-anorexia-nervosa-magnetic-resonance-imaging-and-magnetic-resonance-spectroscopy-assessment
#10
Kirsten Ecklund, Sridhar Vajapeyam, Robert V Mulkern, Henry A Feldman, Jennifer M O'Donnell, Amy D DiVasta, Catherine M Gordon
BACKGROUND: Adolescents and women with anorexia nervosa have increased bone marrow fat and decreased bone formation, at least in part due to hormonal changes leading to preferential stem cell differentiation to adipocytes over osteoblasts. OBJECTIVE: The purpose of this study was to evaluate marrow fat content and correlate with age and disease severity using knee MRI with T1 relaxometry (T1-R) and MR spectroscopy (MRS) in 70 adolescents with anorexia nervosa. MATERIALS AND METHODS: We enrolled 70 girls with anorexia nervosa who underwent 3-T knee MRI with coronal T1-W images, T1-R and single-voxel proton MRS at 30 and 60 ms TE...
April 22, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28430714/ultrasound-molecular-imaging-of-inflammation-in-mouse-abdominal-aorta
#11
Shiying Wang, Sunil Unnikrishnan, Elizabeth B Herbst, Alexander L Klibanov, Frank William Mauldin, John A Hossack
OBJECTIVES: The aim of this study was to demonstrate a new clinically translatable ultrasound molecular imaging approach, modulated acoustic radiation force-based imaging, which is capable of rapid and reliable detection of inflammation as validated in mouse abdominal aorta. MATERIALS AND METHODS: Animal studies were approved by the Institutional Animal Care and Use Committee at the University of Virginia. C57BL/6 mice stimulated with tumor necrosis factor α, or fed with a high-fat diet, were used as inflammation (MInflammation) and diet-induced obesity (DIO) (MDIO) models, respectively...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430118/testing-the-capacity-of-a-multi-nutrient-profiling-system-to-guide-food-and-beverage-reformulation-results-from-five-national-food-composition-databases
#12
Emilie Combet, Antonis Vlassopoulos, Famke Mölenberg, Mathilde Gressier, Lisa Privet, Craig Wratten, Sahar Sharif, Florent Vieux, Undine Lehmann, Gabriel Masset
Nutrient profiling ranks foods based on their nutrient composition, with applications in multiple aspects of food policy. We tested the capacity of a category-specific model developed for product reformulation to improve the average nutrient content of foods, using five national food composition datasets (UK, US, China, Brazil, France). Products (n = 7183) were split into 35 categories based on the Nestlé Nutritional Profiling Systems (NNPS) and were then classified as NNPS 'Pass' if all nutrient targets were met (energy (E), total fat (TF), saturated fat (SFA), sodium (Na), added sugars (AS), protein, calcium)...
April 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28429919/home-availability-of-fruit-and-vegetables-and-obesogenic-foods-as-an-indicator-of-nutrient-intake-in-50-year-olds-from-canterbury-new-zealand
#13
Emily Grant, Richard Blair Gearry, Renée Wilson, John Pearson, Paula Marie Louise Skidmore
BACKGROUND AND OBJECTIVES: The home food environment is known to influence children's diet and selected health outcomes. However, similar research in adults is scarce. The home is arguably the most important food environment for New Zealand adults as the majority of food consumed is stored and prepared in the home. Therefore we investigated relationships between home food availability and nutrient intake in 50 year olds from Canterbury, New Zealand. METHODS AND STUDY DESIGN: A cross-sectional study where participants completed a home food inventory and a four-day estimated food diary...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28429914/the-presence-and-accuracy-of-nutritional-labelling-of-pre-packaged-foods-in-shanghai
#14
Kaimeng Kong, Fu Liu, Yexuan Tao
BACKGROUND AND OBJECTIVES: The Chinese government officially enacted the Regulation on the Management of Food Nutrition Labelling in 2007 and the General Rules for Nutrition Labelling of Pre-packaged Foods in 2011. Our investigation examined the presence and accuracy of nutrition labelling of pre-packaged foods in Shanghai and provides baseline data for future studies. METHODS AND STUDY DESIGN: Nutrition labels on pre-packaged foods were recorded by photograph, transcription, or purchase in four supermarkets in Shanghai...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28429609/chemical-evaluation-of-the-rhynchophorus-ferrugineus-larvae-fed-on-different-substrates-as-human-food-source
#15
Annarita Cito, Santi Longo, Giuseppe Mazza, Elena Dreassi, Valeria Francardi
We investigated the chemical composition of the weevil Rhynchophorus ferrugineus larvae, traditionally used as human food in Asia and known worldwide as one of the most significant pest for palm trees. Total fat content and fatty acid composition were analyzed using standard methodologies in (1) weevil larvae reared on apple fruit slices and wild specimens collected from attacked (2) Phoenix canariensis and (3) Syagrus romanzoffiana palm trees. Total fat content was extremely high in all the specimens (ranged between 57...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28424192/sodium-sugar-and-fat-content-of-complementary-infant-and-toddler-foods-sold-in-the-united-states-2015
#16
Joyce Maalouf, Mary E Cogswell, Marlana Bates, Keming Yuan, Kelley S Scanlon, Pamela Pehrsson, Janelle P Gunn, Robert K Merritt
Background: As part of a healthy diet, limiting intakes of excess sodium, added sugars, saturated fat, and trans fat has been recommended. The American Heart Association recommends that children aged <2 y should avoid added sugars.Objective: We sought to determine commercial complementary infant-toddler food categories that were of potential concern because of the sodium, added sugar, saturated fat, or trans fat content.Design: Nutrition label information (e.g., serving size, sodium, saturated fat, trans fat) for 1032 infant and toddler foods was collected from manufacturers' websites and stores from May to July 2015 for 24 brands, which accounted for >95% of infant-toddler food sales...
April 19, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28424188/nutritional-profile-of-supplemental-nutrition-assistance-program-household-food-and-beverage-purchases
#17
Anna H Grummon, Lindsey Smith Taillie
Background: The Supplemental Nutrition Assistance Program (SNAP), which is the largest federal nutrition assistance program in the United States, serves nearly 1 of 7 Americans. To date, few studies have examined food and beverage purchase behaviors in SNAP participants with the use of electronic purchase data.Objective: In this cross-sectional study, we examined household store purchases of key food, beverage, and nutrient groups in SNAP participants and nonparticipants.Design: Using a data set of US households' (n = 98,256 household-by-quarter observations) packaged food and beverage purchases and SNAP status [current participant, income-eligible nonparticipant (income ≤130% of the Federal Poverty Level [FPL]), and higher-income nonparticipants (income >130% of the FPL)] from 3 quarters during 2012-2013, we estimated pooled ordinary least-squares models, clustered at the household level, to examine the association between SNAP status and purchases while controlling for sociodemographic characteristics...
April 19, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28421282/associations-between-a-mediterranean-diet-pattern-and-inflammatory-biomarkers-in-european-adolescents
#18
Aline Arouca, Nathalie Michels, Luis A Moreno, Esther M González-Gil, Ascensión Marcos, Sonia Gómez, Ligia Esperanza Díaz, Kurt Widhalm, Dénes Molnár, Yannis Manios, Frederic Gottrand, Antonio Kafatos, Mathilde Kersting, Michael Sjöström, Alejandro de la O, Marika Ferrari, Inge Huybrechts, Marcela Gonzalez-Gross, Stefaan De Henauw
AIM: To test whether the Mediterranean diet score and each food-subgroup is associated with inflammatory biomarkers in European adolescents. METHODS: In 464 adolescents (13-17 years) of the European HELENA study, data were available on body composition, inflammation markers, and food intake determined by two computerized 24-h recalls. The Mediterranean diet score and its food-subgroups (Vegetables, Fruits and Nuts, Pulses, Cereal and Roots, Monounsaturated/Saturated fat ratio, Dairy, Fish, Meat and Alcohol) were evaluated...
April 18, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28416500/cluster-randomised-controlled-trial-of-a-consumer-behaviour-intervention-to-improve-healthy-food-purchases-from-online-canteens-study-protocol
#19
Tessa Delaney, Rebecca Wyse, Sze Lin Yoong, Rachel Sutherland, John Wiggers, Kylie Ball, Karen Campbell, Chris Rissel, Luke Wolfenden
INTRODUCTION: School canteens represent an opportune setting in which to deliver public health nutrition strategies given their wide reach, and frequent use by children. Online school canteen ordering systems, where students order and pay for their lunch online, provide an avenue to improve healthy canteen purchases through the application of consumer behaviour strategies that impact on purchasing decisions. The aim of this study is to assess the efficacy of a consumer behaviour intervention implemented in an online school canteen ordering system in reducing the kilojoule, saturated fat, sugar and sodium content of primary student lunch orders...
April 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28412693/feeding-angptl4-mice-trans-fat-promotes-foam-cell-formation-in-mesenteric-lymph-nodes-without-leading-to-ascites
#20
Antwi Boasiako Oteng, Asmita Bhattacharya, Susanne Brodesser, Ling Qi, Nguan Soon Tan, Sander Kersten
ANGPTL4 regulates plasma triglyceride levels by inhibiting lipoprotein lipase. Inactivation of ANGPTL4 decreases plasma triglycerides and reduces risk of coronary artery disease. Unfortunately, targeting ANGPTL4 for the therapeutic management of dyslipidemia and atherosclerosis is hampered by the observation that mice and monkeys in which ANGPTL4 is inactivated exhibit lipid accumulation in mesenteric lymph nodes. In mice these pathological events exclusively unfold upon feeding a high saturated fatty acid diet and are followed by an ultimately lethal pro-inflammatory response and chylous ascites...
April 15, 2017: Journal of Lipid Research
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