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Leonardo Mastropasqua, Mario Nubile
PURPOSE: To investigate the feasibility of the procedure and the modifications of the corneal curvature and profile obtained with a novel technique of stromal-lentoid implantation in ex vivo human corneas. DESIGN: Experimental ex vivo study in human corneas. MATERIALS AND METHODS: Twelve stromal lentoids were produced by means of hyperopic femtosecond lenticule extraction (FLEx) with the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) with a refractive power of +8...
September 15, 2016: International Ophthalmology
Marcus Ang, Mohd Farook, Hla M Htoon, Donald Tan, Jodhbir S Mehta
PURPOSE: To describe simulated night vision, night-vision symptoms, and refractive outcomes after small-incision lenticule extraction. SETTING: Tertiary referral eye center, Singapore. DESIGN: Prospective case series. METHODS: All patients had small-incision lenticule extraction using the Visumax 500 kHz femtosecond laser system. The main outcome measure was simulated night vision logMAR corrected distance visual acuity (CDVA) using the super vision test-night vision goggle vision chart at 12 months...
August 2016: Journal of Cataract and Refractive Surgery
Leonardo Mastropasqua, Roberta Calienno, Manuela Lanzini, Niccolò Salgari, Sergio De Vecchi, Rodolfo Mastropasqua, Mario Nubile
The purpose of this study was to evaluate the incidence of opaque bubble layer (OBL) in femtosecond laser-assisted in situ keratomileusis (LASIK) flaps created with the support of Visumax Carl Zeiss femtosecond laser, planned with different flap diameters (7.90, 8.0, and 8.20 mm) and the same laser energy and power settings. Incidence of intraoperative OBL in flaps of consecutive 108 patients (216 eyes) subjected to bilateral femtosecond-assisted LASIK was considered. Flap creation was performed with the same laser design parameters (spot distance and energy offset) and different presetting diameters of 7...
August 12, 2016: International Ophthalmology
Ihab Mohamed Osman, Hany Ahmed Helaly, Moones Abdalla, Mohsen Abou Shousha
BACKGROUND: Evaluating the corneal biomechanical changes using the Ocular Response Analyzer and the Corvis ST in eyes with incision lenticule extraction (SMILE) and laser assisted in situ keratomileusis (LASIK). METHODS: This is a retrospective study that included 50 eyes equally divided into two groups. The first group included eyes that underwent SMILE procedure using VisuMax® 500 kHz laser system (Carl Zeiss Meditec, Jena, Germany) and the second group included eyes that underwent LASIK procedure using the EX500 Allegretto excimer laser platform (Wavelight GmbH, Erlangen, Germany)...
2016: BMC Ophthalmology
I M Kornilovsky, A I Sultanova, A A Burtsev
UNLABELLED: Photorefractive ablation is inevitably accompanied by oxidative stress of the cornea and weakening of its biomechanical and photoprotective properties. AIM: To validate the expediency of riboflavin use in photorefractive ablation for photoprotection of the cornea and cross-linking. MATERIAL AND METHODS: The effects of riboflavin use in photorefractive ablation was first studied in a series of in vitro and in vivo experiments performed on 56 eyes of 28 rabbits, and then on 232 eyes of 142 patients with different degrees of myopia...
May 2016: Vestnik Oftalmologii
Tamer H Massoud, Osama Ibrahim, Kitty Shehata, Moones F Abdalla
Purpose. To evaluate the visual and refractive outcomes after small incision lenticule extraction (SMILE) for treating myopia and myopic astigmatism after penetrating keratoplasty (PKP). Design. Case-series. Methods. Ten eyes of 10 patients with previous PKP and residual myopic astigmatism for whom pentacam imaging and thickness measurements were acceptable for laser vision correction. Manifest refraction (MR), uncorrected distance visual acuity (UDVA), and corrected distance visual acuity (CDVA) were obtained preoperatively and one day, one week, and one, 3, and 6 months postoperatively...
2016: Journal of Ophthalmology
Dan Z Reinstein, Glenn I Carp, Timothy J Archer, Tariq A Lewis, Marine Gobbe, Johnny Moore, Tara Moore
PURPOSE: To evaluate outcomes of high myopic LASIK using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany). METHODS: Retrospective analysis of 479 consecutive high myopic LASIK procedures (318 patients) using the MEL 80 excimer laser and VisuMax femtosecond laser (Carl Zeiss Meditec) in 77% of cases or zero compression Hansatome microkeratome (Bausch & Lomb, Rochester, NY) in 23% of cases. Inclusion criteria were preoperative spherical equivalent refraction (SEQ) of between -8...
May 1, 2016: Journal of Refractive Surgery
Dorottya Pásztor, Bence Lajos Kolozsvári, Gergely Losonczy, Mariann Fodor
In this study, we present a case of a 58-year-old male patient with oculocutaneous albinism, keratoconus, total cataract, and glaucoma originating from father-daughter incest. He underwent femtosecond laser-assisted keratoplasty with "open-sky" cataract extraction and posterior chamber intraocular lens implantation. One week after surgery his uncorrected visual acuity improved from hand motion to 20/200. Six months later corneal K values were 49.1 D in the flat and 50.0 D in the steep meridian. The graft had a central corneal thickness of 488 µm and was well fitted...
March 2016: Indian Journal of Ophthalmology
S Jalali, W Aus der Au, T Shaarawy
PURPOSE: To evaluate the safety and efficacy of the AcuFocus small aperture corneal inlay (KAMRA) for the correction of presbyopia using femto-LASIK. PATIENTS AND METHODS: This is a prospective, non-randomised cohort study including 50 presbyopic patients with hyperopia, emmetropia or mild myopia. The intracorneal inlay was implanted in the non-dominant eye using a VisuMax femtosecond laser (Zeiss 500 kHz) to create a superior-hinged flap. The inlay was centred over the visual axis...
April 2016: Klinische Monatsblätter Für Augenheilkunde
Kishore R Pradhan, Dan Z Reinstein, Glenn I Carp, Timothy J Archer, Marine Gobbe, Purushottam Dhungana
PURPOSE: To evaluate the outcomes of small-incision lenticule extraction for myopia using the Visumax femtosecond laser at the first refractive surgery unit in Nepal during the first 30 months of operation. SETTING: Tilganga Institute of Ophthalmology, Kathmandu, Nepal. DESIGN: Retrospective noncomparative case series. METHODS: Consecutive myopic small-incision lenticule extraction procedures by a fellowship-trained surgeon were evaluated...
February 2016: Journal of Cataract and Refractive Surgery
Anne Huhtala, Juhani Pietilä, Petri Mäkinen, Hannu Uusitalo
PURPOSE: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre- and postoperative complications as secondary outcomes. METHODS: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK...
2016: Clinical Ophthalmology
Y Yu, X L Cheng, L Q Gu, G J Jing, H Chen
OBJECTIVE: To investigate the clinical efficacy, safety, predictability, corneal sensitivity, tear function and recovery of subbasal nerves after femtosecond lenticule extraction (FLEx) and laser in situ keratomileusis (LASIK). METHODS: In this prospective, nonrandomized, comparative clinical study, 49 patients (98 eyes) were divided into two groups. FLEx was performed to treat myopia by Visumax femtosecond laser system, and LASIK was performed by Allegretto Wave laser system...
March 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Walter Sekundo, Dan Z Reinstein, Marcus Blum
The aim of this study is to establish and to prove a new lenticule shape for the treatment of hyperopia using a 500 kHz femtosecond laser and the femtosecond lenticule extraction (ReLEx FLEx) technique. Improved lenticule shapes with a large transition zone of at least 2 mm adjusted to the 5.75 mm optical zone were designed. A prospective pilot study on nine eyes of five patients who underwent an uncomplicated FLEx using VisuMax femtosecond laser (Carl Zeiss Meditec AG) for spherical hyperopia was performed...
May 2016: Lasers in Medical Science
Ekktet Chansue, Morakot Tanehsakdi, Sukanda Swasdibutra, Colm McAlinden
BACKGROUND: The purpose of this case series is to evaluate the safety and efficacy of VisuMax® Circle patterns in eyes that have undergone small incision lenticule extraction, thus creating a flap to perform an enhancement procedure or residual lenticule extraction. METHODS: This prospective, single center, case study series evaluated the use of a VisuMax® Circle pattern to create a corneal flap following small incision lenticule extraction. Patients were treated and followed at TRSC International LASIK Center (Bangkok, Thailand) for 3 months to assess the efficacy and safety of the procedure...
2015: Eye and Vision (London, England)
Ekktet Chansue, Morakot Tanehsakdi, Sukanda Swasdibutra, Colm McAlinden
BACKGROUND: The purpose of this case series is to report the one-year outcomes of small incision lenticule extraction (SMILE) using the VisuMax® femtosecond laser. METHODS: Two hundred and six patients were recruited for this retrospective, single center study at TRSC International LASIK Center in Bangkok, Thailand. Patients underwent SMILE, whereby an intrastromal lenticule was cut using a femtosecond laser and then manually extracted without the need for flap creation...
2015: Eye and Vision (London, England)
Dan Z Reinstein, Marine Gobbe, Louis Gobbe, Timothy J Archer, Glenn I Carp
PURPOSE: To compare the optical zone centration accuracy between myopic eyes treated with small incision lenticule extraction (SMILE) and LASIK. METHODS: Retrospective analysis of 100 consecutive eyes treated with SMILE (the SMILE group) with the corneal fixation-based centration VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) and a matched group of 100 eyes treated with LASIK (the LASIK group) with VisuMax flap creation and eye tracker-based centration MEL 90 excimer laser (Carl Zeiss Meditec) ablation...
September 2015: Journal of Refractive Surgery
Jose L Güell, Paula Verdaguer, Gloria Mateu-Figueras, Daniel Elies, Oscar Gris, Mostafa A El Husseiny, Felicidad Manero, Mercè Morral
PURPOSE: To study the feasibility of performing myopic femtosecond small incision lenticule extraction (SMILE) with four different cap thicknesses (130, 140, 150, and 160 μm). METHODS: In this retrospective, comparative, non-randomized clinical trial, a refractive lenticule of intrastromal corneal tissue was cut with the VisuMax femtosecond laser system (Carl Zeiss Meditec AG, Jena, Germany) using different depths of the non-refractive lenticule cut. Manifest refraction, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and Objective Scattering Index (OSI) were evaluated...
September 2015: Journal of Refractive Surgery
Shengsheng Wei, Yan Wang, Tong Zuo, Jinyong Lin, Yuchuan Wang
OBJECTIVE: To observe the changes of pathology and ultra- microstructure of corneal lenticules extracted by femtosecond laser small incision lenticule extraction surgery and to investigate instantaneous damage of photodisruption of femtosecond laser to human corneal tissue in vivo. METHODS: The small incision lenticule extraction surgeries in 25 myopic eyes were performed with Carl Zeiss VisuMax femtosecond laser, and the lenticules were observed by light microscopy, scanning electron microscopy and transmission electron microscopy...
July 2015: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Li-Kun Xia, Jie Yu, Guang-Rui Chai, Dang Wang, Yang Li
AIM: To compare refractive results, higher-order aberrations (HOAs), contrast sensitivity and dry eye after laser in situ keratomileusis (LASIK) performed with a femtosecond laser versus a mechanical microkeratome for myopia and astigmatism. METHODS: In this prospective, non-randomized study, 120 eyes with myopia received a LASIK surgery with the VisuMax femtosecond laser for flap cutting, and 120 eyes received a conventional LASIK surgery with a mechanical microkeratome...
2015: International Journal of Ophthalmology
Hyeong-Gi Jung, Jeonghee Kim, Tae-Hyung Lim
PURPOSE: To report the risk factors and clinical effects of an opaque bubble layer (OBL) during creation of a laser in situ keratomileusis (LASIK) flap with the Visumax 500 kHz femtosecond laser. SETTING: HanGil Eye Hospital, Incheon, South Korea. DESIGN: Retrospective comparative study. METHODS: Visual acuity, manifest refraction, intraocular pressure, corneal curvature, corneal thickness, and optical quality were evaluated...
July 2015: Journal of Cataract and Refractive Surgery
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