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small-incision lenticule extraction

Mehdi Shajari, Emanuel Wanner, Vladimir Rusev, Shervin Mir Mohi Sefat, Wolfgang J Mayer, Thomas Kohnen, Siegfried Priglinger, Daniel Kook
PURPOSE: To compare corneal densitometry values after Femtosecond Laser-Assisted In Situ Keratomileusis (Fs-LASIK) and Small Incision Lenticule Extraction (SMILE) using Scheimpflug Imaging. METHODS: Our retrospective clinical trial included a total of 146 eyes where 57 eyes underwent Fs-LASIK and 89 eyes underwent SMILE. Examinations with a Pentacam Scheimpflug device (Oculus, Wetzlar, Germany) were performed before surgery, 1 week, 1 month, 3 months, 6 months, and 1 year after surgery...
March 14, 2018: Current Eye Research
Ikhyun Jun, David Sung Yong Kang, Dan Z Reinstein, Samuel Arba-Mosquera, Timothy J Archer, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism. METHODS: This retrospective, comparative case series study included 89 eyes (89 patients) that received treatment for myopia with high astigmatism (≥ 2.50 diopters) using SMILE with a triple centration technique (SMILE group; 45 eyes) and corneal wavefront-guided transepithelial PRK (transepithelial PRK group; 44 eyes)...
March 1, 2018: Journal of Refractive Surgery
T Liu, T Yu, J Pan, Y C Zou, L N Liu, Q X Kan, J Bai
Objective: To observe the change of refractive status and possible influencing factors for patients with different corneal power who underwent small incision lenticule extraction (SMILE) surgery. Methods: Prospective cohort study was performed for patients who underwent small incision lenticule extraction (SMILE) surgery at Daping Hospital and Research Institute of Surgery of Third Military Medical University between January and August 2016. The patients were divided into 3 groups according to their corneal power: low curvature group (K(1)≤41...
January 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
L Zhang, Y Wang, T Cui, W Zhao, W B Cheng
Objective: To evaluate the changes of corneal transparency over the 1-year period after small incision lenticule extraction (SMILE) according to corneal Scheimpflug densitometry. Methods: Prospective cohort study. Fifty-five patients (100 eyes) with myopia (19 male and 36 female, aged 18 to 39 years with average of 24) who underwent SMILE and regular follow-up for at least 1 year at Tianjin Eye Hospital were enrolled. Examinations took place before SMILE and postoperatively at 1 day, 1 week, and 1, 3, 6, and 12 months...
January 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
F J Zhang, M S Sun
With the development of excimer laser and femtosecond laser equipment, application of diversified and customized surgical decision in modern corneal refractive surgery has been an inevitable trend. However, how to make a personalized decision with an accurate surgical design to achieve better visual quality becomes the main focus in clinical applications. Small-incision lenticule extraction (SMILE) and femtosecond assisted laser in situ keratomileusis (FS-LASIK) have been commonly acknowledged as the mainstream of corneal refractive surgery for ametropia correction nowadays...
January 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Y Wang, J Li
Corneal refractive surgery, as one of the common visual correction methods, has been increasingly accepted in China. There are a large number of people in China who undergo the corneal refractive surgery due to the high incidence of myopia in the country. It is essential that the safest and most effective surgery should be used to correct refractive errors in the cases involved with relatively normal eyes and corneas. In recent years, corneal refractive surgery has been rapidly developing with new technologies and techniques emerging all the time, such as SMILE (small incision lenticule extraction) surgery, which has been extensively applied in China since five years ago when it was approved by FDA...
January 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Iben B Damgaard, Marcus Ang, Mohamed Farook, Hla M Htoon, Jodhbir S Mehta
PURPOSE: To compare intraoperative and postoperative subjective patient experience after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK. METHODS: In a prospective, randomized, paired-eye, single-masked clinical trial at Singapore National Eye Centre, 70 patients were randomly treated with SMILE and LASIK in each eye. The intraoperative questionnaire was completed immediately after surgery and included light perception and levels of anxiety, fear, and discomfort...
February 1, 2018: Journal of Refractive Surgery
Anastasios John Kanellopoulos
Purpose: To investigate ex vivo potentially different corneal biomechanical properties after small-incision lenticule extraction (SMILE) versus LASIK for myopic correction. Methods: Thirty human donor corneas were subjected to either myopic SMILE or femtosecond laser-assisted LASIK. Donor corneas were assigned to six investigative groups: Group A, -3.00 D (diopters) SMILE; Group B, -8.00 D SMILE; Group C, -3.00 D LASIK; and Group D, -8.00 D LASIK. Additionally, two control groups were formed: Group E, SMILE and Group F, LASIK...
2018: Clinical Ophthalmology
Miao He, He Jin, Hong He, Hui Ding, Wei Wang, Liangping Liu, Chi Zhang, Xingwu Zhong
PURPOSE: To evaluate the feasibility and safety of xenogeneic endokeratophakia in rhesus monkeys and to explore the effects of a concave lenticule on refractive power. METHODS: Three adult New Zealand white rabbits and 6 healthy rhesus monkeys were used. The xenogenic concave grafts were created from the rabbits using a modified small incision lenticule extraction technique; after being cryopreserved in glycerol for 1 week, the grafts were implanted into the monkey recipient corneas...
March 2018: Cornea
Jeewan S Titiyal, Manpreet Kaur, Anand S Brar, Ruchita Falera
PURPOSE: To describe our technique of lenticule edge identification in small-incision lenticule extraction using the "meniscus sign" to prevent lenticule misdissection. METHODS: Femtosecond laser application for small-incision lenticule extraction was performed. A "double ring" was visible, signifying the edge of the cap cut (outer ring) and lenticule cut (inner ring). The anterior and posterior lamellar planes were delineated in 2 different directions. During creation of the posterior lamellar channel, the lenticule edge was slightly pushed away from the surgeon to create a gap between the inner ring (diameter of the lenticule cut) and the lenticule edge...
January 29, 2018: Cornea
Yu-Chi Liu, Ericia Pei Wen Teo, Heng Pei Ang, Xin Yi Seah, Nyein Chan Lwin, Gary Hin Fai Yam, Jodhbir S Mehta
Corneal inlays are a relatively new treatment option for presbyopia. Using biological inlays, derived from lenticules extracted from small incision lenticule extraction, may offer advantages over commercialized synthetic inlays in the aspect of biocompatibility. We conducted a non-human primate study to evaluate the safety, predictability, efficacy and tissue response after autogeneic, decellularized xenogeneic and xenogeneic lenticule implantation. The lenticule implantation effectively resulted in central corneal steepening (simulated keratometric values increased by 1...
January 30, 2018: Scientific Reports
Sri Ganesh, Sheetal Brar, Rahul Pandey, Archana Pawar
PURPOSE: To study the time course of interface healing and its correlation with visual acuity, modulation transfer function (MTF), and aberrations after myopic small-incision lenticule extraction (SMILE) correction. METHODS: Seventy-eight eyes of 78 patients (1 eye per patient) with a mean age of 25.7 years and mean spherical equivalent (SE) of -3.74D, undergoing bilateral SMILE procedure, were included in this study. On postoperative day 1, 2 weeks, and 3 months, dilated retroillumination photographs were taken and morphology of corneal interface was graded by comparing them with 5 standard templates representing 5 grades of interface roughness (IRG): IRG - 0 (clear), IRG - 1 (mild), IRG - 2 (moderate), IRG - 3 (severe), and IRG - 4 (severe IRG with Bowman's folds in visual axis)...
February 2018: Indian Journal of Ophthalmology
Liuyang Li, Julie M Schallhorn, Jiaonan Ma, Tong Cui, Yan Wang
PURPOSE: To assess the independent effect of energy setting on postoperative uncorrected distance visual acuity (UDVA) in small incision lenticule extraction (SMILE) and further investigate an optimal energy setting for the 4.5-μm spot-track-distance, which is in wide clinical use. METHODS: A total of 1,130 eyes were included in a retrospective cohort study from Tianjin Eye Hospital, Tianjin Medical University from April 2015 to July 2016. Energy settings and baseline characteristics were recorded and 3-month UDVA was tested by a nurse blinded to the energy settings used...
January 1, 2018: Journal of Refractive Surgery
Sri Ganesh, Sheetal Brar, Raghavender Reddy Arra
Small incision lenticule extraction (SMILE), a variant of refractive lenticule extraction technology is becoming increasingly popular, as a flapless and minimally invasive form of laser vision correction (LVC) for the treatment of myopia and myopic astigmatism. This review aims at summarizing the principles, surgical technique, and clinical outcomes in terms of visual and refractive results, safety, efficacy, postoperative dry eye, aberrations, and biomechanics of SMILE and its comparison with other conventional techniques of LVC, such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK)...
January 2018: Indian Journal of Ophthalmology
Bu Ki Kim, Su Joung Mun, Dae Gyu Lee, Hyun Tae Choi, Young Taek Chung
Purpose: We report a case of incision failure during small incision lenticule extraction (SMILE) and its management. Observations: The incision could not be made using the femtosecond laser because of a redundant conjunctiva, so it was instead done manually using a diamond knife. The lenticule was successfully separated and extracted. Three months after the procedure, the uncorrected distance visual acuity was 20/20 and no complication was observed. Conclusions and importance: This case demonstrates that the conjunctiva should be carefully examined before SMILE...
September 2017: American Journal of Ophthalmology Case Reports
Yang Jiang, Ying Li, Shan Yang, Thomas Chengxuan Lu
Corneal ectasia is a rare but serious post-operative complication of LASIK. Our main aim was to describe and evaluate the efficacy and safety of tuck-in lamellar keratoplasty with an lenticule obtained by SMILE for treatment of Post LASIK Ectasia. Tuck-in lamellar keratoplasty was performed on three post-LASIK cornea ectasia patients (three eyes) with central corneal thickness less than 400 µm. Each patient was monitored for at least 12 months. Our primary outcomes measured pre and post-operatively included: Anterior segment optical coherence tomography(AS-OCT), corneal topography and monitored by slit-lamp microscopy...
December 19, 2017: Scientific Reports
Bing Qin, Meiyan Li, Xun Chen, Walter Sekundo, Xingtao Zhou
PURPOSE: To investigate early visual and refractive outcomes, corneal stability and optical quality after femtosecond laser small-incision lenticule extraction (SMILE) for treating myopia and myopic astigmatism over -10 D. METHODS: Thirty eyes (30 patients) with myopia and myopic astigmatism of over -10 D were treated with VisuMax® femtosecond laser (version 3.0; Carl Zeiss Meditec AG, Jena, Germany). Six months postoperative safety, efficacy and predictability were evaluated...
December 18, 2017: Acta Ophthalmologica
Sri Ganesh, Sheetal Brar, Apostolos Lazaridis
PURPOSE: To describe the management of and report the outcomes following the removal of retained lenticules or lenticule fragments after a complicated small incision lenticule extraction (SMILE). METHODS: Three patients were referred for consultation due to intraoperative complications during SMILE. In case 1, the lenticule was torn during extraction and a central fragment was retained in the pocket. In case 2, the inferior part of the lenticule remained attached at the anterior plane and its detached, superior part was dislocated and folded at the inferior part of the pocket...
December 1, 2017: Journal of Refractive Surgery
Meng Li, Meiyan Li, Ling Sun, Katherine Ni, Xingtao Zhou
PURPOSE: To create a formula to predict refractive correction of autologous lenticule implantation for correction of hyperopia (with myopia in one eye and hyperopia in the contralateral eye). METHODS: In this prospective study, 10 consecutive patients (20 eyes) who had myopia in one eye and hyperopia in the contralateral eye were included. The preoperative spherical equivalent was -3.31 ± 1.73 diopters (D) for the myopic eyes and +4.46 ± 1.97 D for the hyperopic eyes...
December 1, 2017: Journal of Refractive Surgery
Pinghui Wei, Yan Wang, Tommy C Y Chan, Alex L K Ng, George P M Cheng, Vishal Jhanji
PURPOSE: To evaluate the methods to correct corneal power after myopic small-incision lenticule extraction (SMILE) and to estimate the preoperative corneal power based on postoperative values. SETTING: Tianjin Eye Hospital, Tianjin, China. DESIGN: Retrospective case series. METHODS: Equivalent keratometry (K) and mean K readings were obtained with the Pentacam HR. The clinical history method was used to calculate the theoretical postoperative K, which was then compared with equivalent K readings...
November 2017: Journal of Cataract and Refractive Surgery
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