keyword
MENU ▼
Read by QxMD icon Read
search

Phytochemicals

keyword
https://www.readbyqxmd.com/read/28716565/mangiferin-a-phytochemical-with-panacea-potential
#1
EDITORIAL
Abdur Rauf, Muhammad Imranb, Seema Patel
No abstract text is available yet for this article.
July 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28716411/genetic-mitigation-strategies-to-tackle-agricultural-ghg-emissions-the-case-for-biological-nitrification-inhibition-technology
#2
REVIEW
G V Subbarao, J Arango, K Masahiro, A M Hooper, T Yoshihashi, Y Ando, K Nakahara, S Deshpande, I Ortiz-Monasterio, M Ishitani, M Peters, N Chirinda, L Wollenberg, J C Lata, B Gerard, S Tobita, I M Rao, H J Braun, V Kommerell, J Tohme, M Iwanaga
Accelerated soil-nitrifier activity and rapid nitrification are the cause of declining nitrogen-use efficiency (NUE) and enhanced nitrous oxide (N2O) emissions from farming. Biological nitrification inhibition (BNI) is the ability of certain plant roots to suppress soil-nitrifier activity, through production and release of nitrification inhibitors. The power of phytochemicals with BNI-function needs to be harnessed to control soil-nitrifier activity and improve nitrogen-cycling in agricultural systems. Transformative biological technologies designed for genetic mitigation are needed, so that BNI-enabled crop-livestock and cropping systems can rein in soil-nitrifier activity, to help reduce greenhouse gas (GHG) emissions and globally make farming nitrogen efficient and less harmful to environment...
September 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28714318/gc-ms-analysis-of-the-bioactive-phytoconstituents-of-various-organic-crude-extracts-from-the-seed-kernels-of-manilkara-bidentata-balata-collected-in-trinidad-w-i
#3
Yomica L Powder-George, Faisal K Mohammed
The present study reports the first phytochemical investigation of the seed kernels of Manilkara bidentata (Balata) harvested in Trinidad, W.I. Gas chromatography-mass spectrometry (GC-MS) analysis of the n-hexane, chloroform, ethyl acetate, ethanol and methanol extracts showed a total of 39 components. 2,6,10,14,18-pentamethyl-2,6,10,14,18-eicosapentaene (74.93%), 9-octadecenoic acid, (Z)- 2,3-dihydroxypropyl ester (79.98%), (Z)-ethyl oleate (92.75%), Z,E-2-methyl-3,13-octadecadien-1-ol (80.51%) and 5-(hydroxymethyl)-2-furancarboxyaldehyde (50...
July 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28713892/trichostatin%C3%A2-a-induces-bladder-cancer-cell-death-via-intrinsic-apoptosis-at-the-early%C3%A2-phase-and-sp1%C3%A2-survivin-downregulation-at-the-late%C3%A2-phase-of-treatment
#4
Shou-Chieh Wang, Shou-Tsung Wang, Hung-Te Liu, Xiang-Yu Wang, She-Ching Wu, Lei-Chin Chen, Yi-Wen Liu
Histone deacetylase (HDAC) inhibitors have been widely shown to result in cancer cell death. The present study investigated the mechanisms underlying the antitumor effects of the phytochemical trichostatin A (TSA), a classic pan-HDAC inhibitor, in 5,637 urinary bladder cancer cells. It was found that TSA caused cell cycle arrest at the G2/M and G1 phase accompanied by reduced expression of cyclin D1 and upregulated induction of p21. In addition, TSA induced morphological changes, reduced cell viability and apoptotic cell death in 5,637 cells through caspase-3 activation followed by PARP cleavage...
July 6, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28713276/structure-activity-relationships-of-pentacyclic-triterpenoids-as-potent-and-selective-inhibitors-against-human-carboxylesterase-1
#5
Li-Wei Zou, Tong-Yi Dou, Ping Wang, Wei Lei, Zi-Miao Weng, Jie Hou, Dan-Dan Wang, Yi-Ming Fan, Wei-Dong Zhang, Guang-Bo Ge, Ling Yang
Human carboxylesterase 1 (hCE1), one of the most important serine hydrolases distributed in liver and adipocytes, plays key roles in endobiotic homeostasis and xenobiotic metabolism. This study aimed to find potent and selective inhibitors against hCE1 from phytochemicals and their derivatives. To this end, a series of natural triterpenoids were collected and their inhibitory effects against human carboxylesterases (hCEs) were assayed using D-Luciferin methyl ester (DME) and 6,8-dichloro-9,9-dimethyl-7-oxo-7,9-dihydroacridin-2-yl benzoate (DDAB) as specific optical substrate for hCE1, and hCE2, respectively...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28713048/phytochemical-analysis-and-effects-on-ingestive-behaviour-of-a-caralluma-fimbriata-extract
#6
Annabella Vitalone, Antonella Di Sotto, Caterina Loredana Mammola, Rosemarie Heyn, Selenia Miglietta, Paola Mariani, Fabio Sciubba, Passarelli Francesca, Nativio Paola, Gabriela Mazzanti
Caralluma fimbriata Wall. is currently used as a "natural slimming" food supplement, likely due to its content in pregnane glycosides. In the present study, a commercially available Caralluma fimbriata extract (Slimaluma(®); CFE, 100 mg/kg) has been evaluated for its ability to affect the ingestive behaviour in female rats, also with reference to the modulation of brain neuropeptides NPY and ORX.The interference of CFE with α-amylase and lipase has been investigated in vitro, as possible peripheral mechanism of action...
July 13, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28712477/phytochemical-analysis-and-cytotoxicity-evaluation-of-kelussia-odoratissima-mozaff
#7
Amir Abbas Momtazi, Omid Askari-Khorasgani, Elham Abdollahi, Hojjat Sadeghi-Aliabadi, Forough Mortazaeinezhad, Amirhossein Sahebkar
BACKGROUND: Kelussia odoratissima Mozaff. (Apiaceae) is an edible, indigenous, and ethnomedicinal plant that grows only in Iran. Although antioxidant and anti-inflammatory properties of K. odoratissima have been reported, cytotoxic activity of this plant has not been investigated previously. OBJECTIVE: This study aims to evaluate the cytotoxicity of K. odoratissima leaf extract against a panel of human cancer cell lines. A secondary aim was to perform a phytochemical analysis of the plant's leaf oil...
June 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28711545/antiulcer-properties-of-fruits-and-vegetables-a-mechanism-based-perspective
#8
REVIEW
Choudhary Harsha, Kishore Banik, Devivasha Bordoloi, Ajaikumar B Kunnumakkara
Gastric ulcer is the damage caused to mucosal layer of the stomach under the action of various factors like high levels of acid and pepsin, invasion by Helicobacter pylori, etc. Although most cases have been controlled and the rate of ulcer occurrence has reduced over the last few decades, gastric ulcer still holds a prime concern today. A range of palliative medicines comprising proton pump inhibitors, H2 receptor antagonists, COX-2 inhibitors (coxibs) is widely in use and patients have also been administered with acid suppression therapies...
July 12, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28710570/a-methoxyflavanone-derivative-from-the-asian-medicinal-herb-perilla-frutescens-induces-p53-mediated-g2-m-cell-cycle-arrest-and-apoptosis-in-a549-human-lung-adenocarcinoma
#9
Amer Ali Abd El-Hafeez, Takashi Fujimura, Rikiya Kamei, Noriko Hirakawa, Kenji Baba, Kazuhisa Ono, Seiji Kawamoto
Perilla frutescens is an Asian dietary herb consumed as an essential seasoning in Japanese cuisine as well as used for a Chinese medicine. Here, we report that a newly found methoxyflavanone derivative from P. frutescens (Perilla-derived methoxyflavanone, PDMF; 8-hydroxy-5,7-dimethoxyflavanone) shows carcinostatic activity on human lung adenocarcinoma, A549. We found that treatment with PDMF significantly inhibited cell proliferation and decreased viability through induction of G2/M cell cycle arrest and apoptosis...
July 14, 2017: Cytotechnology
https://www.readbyqxmd.com/read/28709400/broad-range-potential-of-asphodelus-microcarpus-leaves-extract-for-drug-development
#10
Amalia Di Petrillo, Antonella Fais, Francesca Pintus, Celestino Santos-Buelga, Ana M González-Paramás, Vincenzo Piras, Germano Orrù, Antonello Mameli, Enzo Tramontano, Aldo Frau
BACKGROUND: Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities. In order to find novel antimicrobial and antiviral agents, the aim of the present study was the evaluation of the antibacterial and antibiofilm susceptibility of Asphodelus microcarpus leaves extract. Moreover, the antiviral activity and the phytochemical composition of the active extract were also determined...
July 14, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28708113/dietary-phytochemicals-promote-health-by-enhancing-antioxidant-defence-in-a-pig-model
#11
Sophie N B Selby-Pham, Jeremy J Cottrell, Frank R Dunshea, Ken Ng, Louise E Bennett, Kate S Howell
Phytochemical-rich diets are protective against chronic diseases and mediate their protective effect by regulation of oxidative stress (OS). However, it is proposed that under some circumstances, phytochemicals can promote production of reactive oxygen species (ROS) in vitro, which might drive OS-mediated signalling. Here, we investigated the effects of administering single doses of extracts of red cabbage and grape skin to pigs. Blood samples taken at baseline and 30 min intervals for 4 hours following intake were analyzed by measures of antioxidant status in plasma, including Trolox equivalent antioxidant capacity (TEAC) and glutathione peroxidase (GPx) activity...
July 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28706420/maytenus-erythroxylon-reissek-celastraceae-ethanol-extract-presents-antidiarrheal-activity-via-antimotility-and-antisecretory-mechanisms
#12
Rodrigo de Oliveira Formiga, Zelma Glebya Maciel Quirino, Margareth de Fátima Formiga Melo Diniz, Alexsandro Fernandes Marinho, Josean Fechine Tavares, Leônia Maria Batista
AIM: To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS: A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used to evaluate a possible antimotility effect. KATP channels, nitric oxide, presynaptic α2-adrenergic and tissue adrenergic receptors were investigated to uncover antimotility mechanisms of action and castor oil-induced enteropooling to elucidate antisecretory mechanisms...
June 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28705748/effect-of-secondary-metabolite-of-actinidia-deliciosa-on-the-biofilm-and-extra-cellular-matrix-components-of-acinetobacter-baumannii
#13
Vishvanath Tiwari, Deepika Tiwari, Varsha Patel, Monalisa Tiwari
Acinetobacter baumannii, opportunistic nosocomial pathogen, increases gradually in the clinical setup. The high level of resistance mechanisms acquired by these bacteria makes their eradication difficult and biofilm formation is one of them. Biofilm comprises of closely packed bacterial population crowded together by extra-cellular matrix (ECM). ECM contains bacterial secreted polymers such as exopolysaccharides (EPS), proteins and extracellular-DNA (e-DNA) and rarely amyloidogenic proteins. Biofilm offers protection of underlying bacterial population against chemotherapeutic agents and host immune system...
July 10, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28705747/synthesis-of-phytochemicals-stabilized-gold-nanoparticles-and-their-biological-activities-against-bacteria-and-leishmania
#14
Aftab Ahmad, Yun Wei, Sadeeq Ullah, Sayyed Ibrahim Shah, Fazli Nasir, Akram Shah, Zafar Iqbal, Kamran Tahir, Usman Ali Khan, Qipeng Yuan
Nanoscale materials have shown promising results in the field of medicine as therapeutic agents and drugs delivery vehicles. In the current study, gold nanoparticles (AuNPs) were prepared by a green and facile method using the aqueous extract of Rhazya stricta decne as a source of reducing and stabilizing agents. The bio-fabricated AuNPs were characterized by UV-visible spectroscopy, X-ray diffraction (XRD), Transmission electron microscopy (TEM) and FTIR spectroscopy. Antimicrobial activities of the biosynthesized AuNPs were tested against Leishmania tropica (HTD7), E...
July 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28704688/occurrences-biosynthesis-and-properties-of-aurones-as-high-end-evolutionary-products
#15
REVIEW
Benjamin Boucherle, Marine Peuchmaur, Ahcène Boumendjel, Romain Haudecoeur
Recent years have witnessed a considerable renewed interest for the uncommon flavonoid class of aurones. The characterization of two major biosynthetic machineries involved in their biosynthesis in flowers has encouraged the revival of phytochemical studies and identification of original structures, a process started almost seventy-five years ago. This review draws up an exhaustive map of natural occurrences of aurones their biosynthetic pathways and roles, with the aim to link their original structural properties among flavonoids to their place in evolution and the selective advantages they bring to some of the most advanced taxa in the plant kingdom...
July 10, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28703962/haematological-and-biochemical-studies-on-justicia-carnea-leaves-extract-in-phenylhydrazine-induced-anemia-in-albino-rats
#16
Chimaraoke Onyeabo, Ngozi K Achi, Chima A Ekeleme-Egedigwe, Chidinma U Ebere, Chidinma K Okoro
BACKGROUND: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Aim. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. METHODS: The experimental animals were randomly grouped into five groups of six rats each – group 1 (non-anemic control), group 2 (anemic control), group 3 (500 mg/kg of JC extract), group 4 (1000 mg/kg of JC extract) and group 5 (DMSO control)...
April 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28702429/wild-mushrooms-a-potential-source-of-nutritional-and-antioxidant-attributes-with-acceptable-toxicity
#17
Sumaira Sharif, Muhammad Shahid, Muhammad Mushtaq, Sumia Akram, Ayoub Rashid
This paper describes in detail proximate composition, nutritional profile, phytochemical constituents, antioxidant activities, antimicrobial potential, and antihemolytic activity (towards human erythrocytes) of various fractions of wild Ganoderma lucidum. Proximate analysis established that wild G. lucidum comprises about 87.02±5.45% of moisture, and the remaining part is a rich source of proteins (8.59±0.37%), crude fiber (54.21±1.2%), and carbohydrate (35.16%) with smaller fat content (3.33 %). Similarly, phytochemical screening revealed the presence of flavonoids (217...
June 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28702037/transcriptomic-response-of-purple-willow-salix-purpurea-to-arsenic-stress
#18
Aymeric Yanitch, Nicholas J B Brereton, Emmanuel Gonzalez, Michel Labrecque, Simon Joly, Frederic E Pitre
Arsenic (As) is a toxic element for plants and one of the most common anthropogenic pollutants found at contaminated sites. Despite its severe effects on plant metabolism, several species can accumulate substantial amounts of arsenic and endure the associated stress. However, the genetic mechanisms involved in arsenic tolerance remains obscure in many model plant species used for land decontamination (phytoremediation), including willows. The present study assesses the potential of Salix purpurea cv. 'Fish Creek' for arsenic phytoextraction and reveals the genetic responses behind arsenic tolerance, phytoextraction and metabolism...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28701702/the-influence-of-postharvest-uv-c-treatment-on-anthocyanin-biosynthesis-in-fresh-cut-red-cabbage
#19
Jie Wu, Wen Liu, Li Yuan, Wen-Qiang Guan, Charles S Brennan, Yang-Yong Zhang, Jie Zhang, Zhi-Dong Wang
Red cabbage (Brassica oleracea L. var. capitata f. rubra DC.) is a fresh edible vegetable consumed globally that contains high levels of antioxidant compounds including anthocyanins. In this study, fresh-cut red cabbage was treated with different Ultraviolet-C (UV-C) dosages. Fifteen cyanidin derivatives were observed in UV-C treated fresh-cut red cabbage; four of these were anthocyanins absent in control samples. The optimum dose of UV-C for enhancing total anthocyanin content in fresh-cut red cabbage was 3...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28701018/bioactive-triterpenoids-from-the-leaves-and-twigs-of-lithocarpus-litseifolius-and-l-%C3%A2-corneus
#20
Yuan-Bin Cheng, Fan-Jin Liu, Chih-Hsin Wang, Tsong-Long Hwang, Yung-Fong Tsai, Chia-Hung Yen, Hui-Chun Wang, Yen-Hsueh Tseng, Ching-Te Chien, Yi-Ming Arthur Chen, Fang-Rong Chang, Yang-Chang Wu
Phytochemical investigation of the leaves and twigs of Lithocarpus litseifolius and Lithocarpus corneus resulted in the isolation of four new triterpenoids (1-4), three triterpenoids (5-7) isolated from a natural source for the first time, and six known compounds (8-13). In addition, four known triterpenoids (14-17) were isolated from L. corneus. Compound 1 is a 3,4-seco-lupane-type triterpenoid, and compounds 2-4 are lupane-type triterpenoids in different oxidation states. The structures of all isolated compounds were identified by spectroscopic methods, especially NMR and mass spectrometry data...
July 12, 2017: Planta Medica
keyword
keyword
21609
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"