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https://www.readbyqxmd.com/read/28532415/hemodynamic-changes-caused-by-acupuncture-in-healthy-volunteers-a-prospective-single-arm-exploratory-clinical-study
#1
Tae-Hun Kim, Boncho Ku, Jang-Han Bae, Jae-Young Shin, Min-Ho Jun, Jung Won Kang, Junghwan Kim, Jun-Hwan Lee, Jaeuk U Kim
BACKGROUND: Radial pressure pulse wave (RPPW) examination has been a key diagnostic component of traditional Chinese medicine. The objective of this study was to investigate the changes in RPPW along with various hemodynamic variables after acupuncture stimulation and to examine the validity of pulse diagnosis as a modern diagnostic tool. METHODS: We conducted acupuncture stimulation at both ST36 acupuncture points in 25 healthy volunteers. We simultaneously assessed the RPPW by pulse tonometry; heart rate variability (HRV) by electrocardiogram; photoplethysmogram (PPG) signals, respiration rate, peripheral blood flow velocity and arterial depth by ultrasonography; and cardiac output by impedance cardiography, before, during and after a session of acupuncture stimulation...
May 22, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28531140/a-cuffless-blood-pressure-measurement-based-on-the-impedance-plethysmography-technique
#2
Shing-Hong Liu, Da-Chuan Cheng, Chun-Hung Su
In the last decade, cuffless blood pressure measurement technology has been widely studied because it could be applied to a wearable apparatus. Electrocardiography (ECG), photo-plethysmography (PPG), and phonocardiography are always used to detect the pulse transit time (PTT) because the changed tendencies of the PTT and blood pressure have a negative relationship. In this study, the PPG signal was replaced by the impedance plethysmography (IPG) signal and was used to detect the PTT. The placement and direction of the electrode array for the IPG measurement were discussed...
May 21, 2017: Sensors
https://www.readbyqxmd.com/read/28526082/proof-of-concept-non-invasive-estimation-of-peripheral-venous-oxygen-saturation
#3
Musabbir Khan, Chris G Pretty, Alexander C Amies, Joel Balmer, Houda E Banna, Geoffrey M Shaw, J Geoffrey Chase
BACKGROUND: Pulse oximeters continuously monitor arterial oxygen saturation. Continuous monitoring of venous oxygen saturation (SvO2) would enable real-time assessment of tissue oxygen extraction (O2E) and perfusion changes leading to improved diagnosis of clinical conditions, such as sepsis. METHODS: This study presents the proof of concept of a novel pulse oximeter method that utilises the compliance difference between arteries and veins to induce artificial respiration-like modulations to the peripheral vasculature...
May 19, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28502104/assess-pain-intensity-using-photoplethysmography-signal-in-chronic-myofascial-pain-syndrome
#4
Jing-Jhao Ye, Kuan-Ting Lee, Ying-Yu Chou, Hung-Hai Sie, Ju-Nan Huang, Chiung-Cheng Chuang
BACKGROUND: Efficacy of pain assessment is the basis for effective therapy. Clinically, assessing pain is by subjective scale, but these methods have some shortcomings. Therefore, studies have been conducted on assessment of pain using physiological signals. Photoplethysmography (PPG) signal provides much information about the cardiovascular system. PPG- derived parameters (PPG parameters) reflect nociceptive stimulation, and obtain an approximation of the R-R interval from PPG period...
May 14, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28489547/a-172-%C3%AE-w-compressively-sampled-photoplethysmographic-ppg-readout-asic-with-heart-rate-estimation-directly-from-compressively-sampled-data
#5
Venkata Rajesh Pamula, Jose Manuel Valero-Sarmiento, Long Yan, Alper Bozkurt, Chris Van Hoof, Nick Van Helleputte, Refet Firat Yazicioglu, Marian Verhelst
A compressive sampling (CS) photoplethysmographic (PPG) readout with embedded feature extraction to estimate heart rate (HR) directly from compressively sampled data is presented. It integrates a low-power analog front end together with a digital back end to perform feature extraction to estimate the average HR over a 4 s interval directly from compressively sampled PPG data. The application-specified integrated circuit (ASIC) supports uniform sampling mode (1x compression) as well as CS modes with compression ratios of 8x, 10x, and 30x...
May 8, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28483786/faster-aspart-versus-insulin-aspart-as-part-of-a-basal-bolus-regimen-in-inadequately-controlled-type-2-diabetes-the-onset-2-trial
#6
Keith Bowering, Christopher Case, John Harvey, Michael Reeves, Michael Sampson, Robert Strzinek, Ditte-Marie Bretler, Rikke Beck Bang, Bruce W Bode
OBJECTIVE: This multicenter, double-blind, treat-to-target, phase 3 trial evaluated the efficacy and safety of fast-acting insulin aspart (faster aspart) versus insulin aspart (IAsp) in adults with type 2 diabetes receiving basal insulin and oral antidiabetic agents. RESEARCH DESIGN AND METHODS: The primary end point was HbA1c change from baseline after 26 weeks' treatment. After an 8-week run-in to optimize basal insulin, subjects were randomized (1:1) to mealtime faster aspart (n = 345) or IAsp (n = 344), titrated using a simple daily patient-driven algorithm, plus insulin glargine U100 and metformin...
May 8, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28476975/peripheral-arterial-disease-screening-for-hemodialysis-patients-using-a-fractional-order-integrator-and-transition-probability-decision-making-model
#7
Jian-Xing Wu, Chien-Ming Li, Guan-Chun Chen, Yueh-Ren Ho, Chia-Hung Lin
Atherosclerosis and resultant peripheral arterial disease (PAD) are common complications in patients with type 2 diabetes mellitus or end-stage renal disease and in elderly patients. The prevalence of PAD is higher in patients receiving haemodialysis therapy. For early assessment of arterial occlusion using bilateral photoplethysmography (PPG), such as changes in pulse transit time and pulse shape, bilateral timing differences could be used to identify the risk level of PAD. Hence, the authors propose a discrete fractional-order integrator to calculate the bilateral area under the systolic peak (AUSP)...
April 2017: IET Systems Biology
https://www.readbyqxmd.com/read/28474401/a-review-of-glucagon-like-peptide-1-receptor-agonists-and-their-effects-on-lowering-postprandial-plasma-glucose-and-cardiovascular-outcomes-in-the-treatment-of-type-2-diabetes-mellitus
#8
REVIEW
D R Owens, L Monnier, M Hanefeld
Type 2 diabetes mellitus (T2DM) is an independent risk factor for cardiovascular (CV) comorbidities, with CV disease being the most common cause of death in adults with T2DM. Although glucocentric therapies may improve glycaemic control (as determined by glycated haemoglobin levels), evidence suggests that this approach alone has limited beneficial effects on CV outcomes relative to improvements in lipid and blood pressure control. This may be explained in part by the fact that current antidiabetic treatment regimens primarily address overall glycaemia and/or fasting plasma glucose, but not the postprandial plasma glucose (PPG) excursions that have a fundamental causative role in increasing CV risk...
May 4, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28471970/evaluation-of-pulse-oximeter-derived-photoplethysmographic-signals-for-obstructive-sleep-apnea-diagnosis
#9
Yan Li, He Gao, Yan Ma
High prevalence of obstructive sleep apnea (OSA) has increased the demands for more convenient and accessible diagnostic devices other than standard in-lab polysomnography (PSG). Despite the increasing utility of photoplethysmograph (PPG), it remains understudied in underserved populations. This study aimed to evaluate the reliability of a standard pulse oximeter system with an automated analysis based on the PPG signal for the diagnosis of OSA, as compared with PSG derived measures.Consecutive out-patients with suspect OSA completed a PPG monitoring simultaneous with an overnight in-lab standard PSG...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28469670/the-effect-of-tracheal-intubation-induced-autonomic-response-on-photoplethysmography
#10
Pekka Talke
Introduction. Intraoperative stress responses and postoperative pain can be monitored using photoplethysmography (PPG). PPG signal has two components, AC and DC. Effects of noxious stimuli-induced stress responses have not been studied on the DC component of PPG. The aim of this study was to investigate the effect of a known noxious stimulus (endotracheal intubation) on both the AC and DC components of PPG. Methods. 15 surgical patients having general anesthesia were enrolled into this clinical study. PPG was recorded electronically from a pulse oximeter...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28469198/photoplethysmography-for-the-assessment-of-haemorheology
#11
Haneen Njoum, Panayiotis A Kyriacou
Haemorheology has been long identified as an early biomarker of a wide range of diseases, especially cardiovascular diseases. This study investigates for the first time the suitability of Photoplethysmography (PPG) as a non-invasive diagnostic method for haemorheological changes. The sensitivity of both PPG components (AC and DC) to changes in haemorheology were rigorously investigated in an in vitro experimental setup that mimics the human circulation. A custom-made reflectance PPG sensor, a pressure transducer and an ultrasonic Doppler flowmeter were used to map changes in flow dynamics and optical responses in an arterial model...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28459679/parhelia-particle-filter-based-heart-rate-estimation-from-photoplethysmographic-signals-during-physical-exercise
#12
Yuya Fujita, Masayuki Hiromoto, Takashi Sato
The photoplethysmographic (PPG) signal is an important source of information for estimating heart rate (HR). However, the PPG signal could be strongly contaminated by the motion artifact (MA) of the subjects, making HR estimation a particularly difficult problem. In this paper, we propose PARHELIA, a PARticle filter-based algorithm for HEart rate estimation using photopLethysmographIc signAls. The proposed method employs a particle filter, and utilizes the simultaneously recorded acceleration signals from a wrist-type sensor, to keep track of multiple HR candidates...
April 25, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28436909/pulse-transit-time-measurement-using-seismocardiogram-photoplethysmogram-and-acoustic-recordings-evaluation-and-comparison
#13
Chenxi Yang, Negar Tavassolian
This work proposes a novel method of pulse transit time measurement. The proximal arterial location data is collected from seismocardiogram (SCG) recordings by placing a MEMS accelerometer on the chest wall. The distal arterial location data is recorded using an acoustic sensor placed inside the ear. The performance of distal location recordings is evaluated by comparing SCG-acoustic and SCG-Photoplethysmogram (PPG) measurements. PPG and acoustic performances under motion noise are also compared. Experimental results suggest comparable performances for the acoustic-based and PPG-based devices...
April 24, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28434857/a-study-evaluating-the-postprandial-plasma-glucose-control-among-type-2-diabetes-patients-attending-a-teaching-hospital-in-malaysia
#14
REVIEW
Salwa Selim Ibrahim Abougalambou, Nahid Osman Ahmed, Ayman S Abougalambou
BACKGROUND AND OBJECTIVE: Type 2 DM is rapidly rising as a global health care problem that threatens to reach pandemic levels by 2030. Type 2 diabetes mellitus is a disease with no cure and chronic disease that results in major morbidity and mortality. The main objective of this study is to evaluate postprandial plasma glucose level and to determine factors affect on postprandial plasma glucose level among type 2 diabetes outpatients attending endocrinology clinics at Hospital Universiti Sains Malaysia, Teaching Hospital...
April 10, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28433435/fabric-phase-sorptive-extraction-as-a-reliable-tool-for-rapid-screening-and-detection-of-freshness-markers-in-oranges
#15
M Aznar, S Úbeda, C Nerin, A Kabir, K G Furton
A simple, fast and sensitive analyte extraction method based on fabric phase sorptive extraction (FPSE) followed by gas chromatography-mass spectrometry (GC-MS) and ultra-performance liquid chromatography-quadrupole time of flight mass spectrometry (UPLC-QTOF-MS) analysis was developed for the analysis of 12 volatile compounds that represent most of the principal chemical families possessing different polarities and volatilities. Five FPSE media coated with different sol-gel sorbent chemistries having different polarities and selectivities were studied: long chain poly(dimethylsiloxane) (PDMS), short chain poly(tetrahydrofuran) (PTHF), Carbowax 20M (CW20M), short chain poly(dimethyl siloxane) (SC PDMS) and polyethylene glycol-polypropylene glycol-polyethylene glycol triblock copolymer (PEG-PPG-PEG)...
April 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28432748/future-challenges-and-therapeutic-opportunities-in-type-2-diabetes-changing-the-paradigm-of-current-therapy
#16
REVIEW
D R Owens, L Monnier, A H Barnett
Most algorithms for type 2 diabetes mellitus (T2DM) do not recommend treatment escalation until glycated haemoglobin (HbA1c) fails to reach the recommended target of 7% (53 mmol/mol) within approximately 3 months on any treatment regimen ('treat to failure'). Clinical inertia and/or poor adherence to therapy contribute to patients not reaching glycaemic targets when managed according to this paradigm. Clinical inertia exists across the entire spectrum of anti-diabetes therapies, although it is most pronounced when initiating and optimizing insulin therapy...
April 21, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28420086/blockwise-ppg-enhancement-based-on-time-variant-zero-phase-harmonic-notch-filtering
#17
Chanki Park, Hyunsoon Shin, Boreom Lee
So far, many approaches have been developed for motion artifact (MA) reduction from photoplethysmogram (PPG). Specifically, single-input MA reduction methods are useful to apply wearable and mobile healthcare systems because of their low hardware costs and simplicity. However, most of them are insufficiently developed to be used in real-world situations, and they suffer from a phase distortion problem. In this study, we propose a novel single-input MA reduction algorithm based on time-variant forward-backward harmonic notch filtering...
April 14, 2017: Sensors
https://www.readbyqxmd.com/read/28416494/long-term-clinical-course-of-normotensive-preperimetric-glaucoma
#18
Akira Sawada, Yusuke Manabe, Tetsuya Yamamoto, Chisato Nagata
AIMS: To evaluate the long-term clinical course of normotensive preperimetric glaucoma (PPG). METHODS: We retrospectively analysed 130 eyes of 130 patients initially diagnosed as having preperimetric normal tension glaucoma and followed these cases for at least 5 years with reliable visual field (VF) examinations by standard automated perimetry. When the VF defect (VFD) met Anderson-Patella's criteria on three or more consecutive examinations, and consistently met the criteria on subsequent examinations, we concluded that a glaucomatous VFD was present...
April 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28408695/effect-of-exercise-timing-on-elevated-postprandial-glucose-levels
#19
Yoichi Hatamoto, Ryoma Goya, Yosuke Yamada, Eichi Yoshimura, Sena Nishimura, Yasuki Higaki, Hiroaki Tanaka
There is no consensus regarding optimal exercise timing for reducing post prandial glucose (PPG). The purpose of the present study was to determine the most effective exercise timing. Eleven participants completed four different exercise patterns 1) no exercise; 2) preprandial exercise (jogging); 3) postprandial exercise; and 4) brief periodic exercise intervention (3 sets of 1 min jogging + 30 s rest, every 30 min, 20 times total)] in a random order separated by a minimum of five days. Pre- and postprandial exercise consisted of 20 sets of intermittent exercise (1 min jogging + 30 s rest per set) repeated 3 times per day...
April 13, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28408352/characterization-and-spatiotemporal-expression-of-gonadotropin-releasing-hormone-in-the-pacific-abalone-haliotis-discus-hannai
#20
Tae Ha Kim, Mi Ae Kim, Kyeong Seop Kim, Jae Won Kim, Han Kyu Lim, Jung Sick Lee, Young Chang Sohn
Gonadotropin-releasing hormone (GnRH) is a key neuropeptide regulating reproduction in humans and other vertebrates. Recently, GnRH-like cDNAs and peptides were reported in marine mollusks, implying that GnRH-mediated reproduction is an ancient neuroendocrine system that arose prior to the divergence of protostomes and deuterostomes. Here, we evaluated the reproductive control system mediated by GnRH in the Pacific abalone Haliotis discus hannai. We cloned a prepro-GnRH cDNA (Hdh-GnRH) from the pleural-pedal ganglion (PPG) in H...
July 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
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