keyword
https://read.qxmd.com/read/38500905/comprehensive-review-on-pancreatic-head-cancer-pathogenesis-diagnosis-and-treatment-challenges-in-the-quest-for-improved-survival
#1
REVIEW
Shreya Singh, Anupama Sawal
This comprehensive review explores the complexities surrounding pancreatic head cancer, a highly fatal and challenging-to-treat illness with a survival rate of less than five years. Despite being a major contributor to cancer-related deaths, pancreatic head malignancy often eludes early detection due to its posterior location and high metastatic potential. The review delves into the associated symptoms, including gastric outlet obstruction and obstructive jaundice, highlighting the impact on the patient's eligibility for surgery...
February 2024: Curēus
https://read.qxmd.com/read/38425267/the-need-for-standardized-perioperative-care-for-patients-undergoing-bariatric-and-metabolic-surgery-in-the-united-kingdom
#2
JOURNAL ARTICLE
Shiela Lee, Michael Courtney
Enhanced recovery after surgery (ERAS) protocols are shown to improve patient outcomes and reduce length of hospital stay. However, there is currently limited consensus on the perioperative management of patients undergoing bariatric and metabolic surgery (BMS) in the United Kingdom. This study aims to survey the level of consistency in patient care undergoing BMS. Bariatric nurse specialists from 30 bariatric units completed an anonymised, online survey from 21 December 2022 to 21 February 2023. Most units (77%) have implemented a premade postoperative care bundle protocol including predetermined timing of oral intake (77%) and postoperative day 1 bloods (60%)...
March 1, 2024: Clinical Obesity
https://read.qxmd.com/read/38241077/a-nationwide-chronic-disease-management-solution-via-clinical-decision-support-services-software-development-and-real-life-implementation-report
#3
JOURNAL ARTICLE
Mustafa Mahir Ulgu, Gokce Banu Laleci Erturkmen, Mustafa Yuksel, Tuncay Namli, Şenan Postacı, Mert Gencturk, Yildiray Kabak, A Anil Sinaci, Suat Gonul, Asuman Dogac, Zübeyde Özkan Altunay, Banu Ekinci, Sahin Aydin, Suayip Birinci
BACKGROUND: The increasing population of older adults has led to a rise in the demand for health care services, with chronic diseases being a major burden. Person-centered integrated care is required to address these challenges; hence, the Turkish Ministry of Health has initiated strategies to implement an integrated health care model for chronic disease management. We aim to present the design, development, nationwide implementation, and initial performance results of the national Disease Management Platform (DMP)...
January 19, 2024: JMIR Medical Informatics
https://read.qxmd.com/read/37938079/day-surgery-adult-patients-with-obesity-and-obstructive-sleep-apnea-current-controversies-and-concerns
#4
REVIEW
Omaira Azizad, Girish P Joshi
Obesity and obstructive sleep apnea are considered independent risk factors that can adversely affect perioperative outcomes. A combination of these two conditions in the ambulatory surgery patient can pose significant challenges for the anesthesiologist. Nevertheless, these patients should not routinely be denied access to ambulatory surgery. Instead, patients should be appropriately optimized. Anesthesiologists and surgeons must work together to implement fast-track anesthetic and surgical techniques that will ensure successful ambulatory outcomes...
September 2023: Best Practice & Research. Clinical Anaesthesiology
https://read.qxmd.com/read/37924061/the-transit-of-oral-premedication-beyond-the-stomach-in-patients-undergoing-laparoscopic-sleeve-gastrectomy-a-retrospective-observational-multicentre-study
#5
MULTICENTER STUDY
Laurence Weinberg, Nick Scurrah, Tom Neal-Williams, Wendell Zhang, Sharon Chen, Hugh Slifirski, David S Liu, Angelica Armellini, Ahmad Aly, Anthony Clough, Dong-Kyu Lee
BACKGROUND: Antiemetic and analgesic oral premedications are frequently prescribed preoperatively to enhance recovery after laparoscopic sleeve gastrectomy. However, it is unknown whether these medications transit beyond the stomach or if they remain in the sleeve resection specimen, thereby negating their pharmacological effects. METHODS: A retrospective cohort study was performed on patients undergoing laparoscopic sleeve gastrectomy and receiving oral premedication (slow-release tapentadol and netupitant/palonosetron) as part of enhanced recovery after bariatric surgery program...
November 4, 2023: BMC Surgery
https://read.qxmd.com/read/37880756/trajectory-patterns-of-metabolic-syndrome-severity-score-and-risk-of-type-2-diabetes
#6
JOURNAL ARTICLE
Atieh Amouzegar, Mohammadjavad Honarvar, Safdar Masoumi, Davood Khalili, Fereidoun Azizi, Ladan Mehran
BACKGROUND: The available evidence indicates that the severity of metabolic syndrome tends to worsen progressively over time. We assessed the trajectory of age and sex-specific continuous MetS severity score (cMetS-S) and its association with the development of diabetes during an 18-year follow-up. METHODS: In a prospective population-based Tehran Lipid and Glucose Study, 3931 eligible participants free of diabetes, aged 20-60 years, were followed at three-year intervals...
October 25, 2023: Journal of Translational Medicine
https://read.qxmd.com/read/37864002/left-atrial-remodeling-in-adolescents-with-obesity-evaluated-by-speckle-tracking-echocardiography
#7
JOURNAL ARTICLE
Justine Paysal, Etienne Merlin, Emmanuelle Rochette, Daniel Terral, Stéphane Nottin
BACKGROUND AND AIMS: In adolescents with obesity, a left atrial (LA) enlargement has been reported. However, data regarding its function and its stiffness are missing. The aim of this study was to describe LA morphology and function, using speckle-tracking echocardiography (STE) and to explore their potential determinants in adolescents with obesity. METHODS: Twenty-eight adolescent women with obesity (13.2 ± 1.4 yr) with an illness duration of 130 ± 27 months and 33 controls (14...
October 20, 2023: International Journal of Obesity
https://read.qxmd.com/read/37821695/-indications-and-preoperative-planning-for-bariatric-surgery
#8
JOURNAL ARTICLE
Daniel Moritz Felsenreich, Andrea Malzner, Marlies Eichner, Elisabeth Hoelbing, Alexander Moosbrugger, Philipp Beckerhinn, Gerhard Prager, Johanna Maria Brix, Bianca-Karla Itariu
These clinical practice guidelines represent the consensus opinion of a group of Austrian specialist physicians associated with the treatment of obesity. The recommendations incorporate the current literature and guidelines and aim to balance both procedural feasibility and patient acceptance and adherence. Special emphasis was placed on simplification of the preoperative clarification and maximum patient safety. Therefore, this article makes no claim to be complete in all fields.
November 2023: Wiener Klinische Wochenschrift
https://read.qxmd.com/read/37641942/resting-energy-metabolism-and-sweet-taste-preference-during-the-menstrual-cycle-in-healthy-women
#9
JOURNAL ARTICLE
Lorena Malo-Vintimilla, Carolina Aguirre, Angie Vergara, Rodrigo Fernández-Verdejo, Jose E Galgani
Differences in blood concentration of sex hormones in the follicular (FP) and luteal (LP) phases may influence energy metabolism in women. We compared fasting energy metabolism and sweet taste preference on a representative day of the FP and LP in twenty healthy women (25·3 (sd 5·1) years, BMI: 22·2 (sd 2·2) kg/m2 ) with regular self-reported menses and without the use of hormonal contraceptives. From the self-reported duration of the three prior menstrual cycles, the predicted FP and LP visits were scheduled for days 5-12 and 20-25 after menses, respectively...
February 14, 2024: British Journal of Nutrition
https://read.qxmd.com/read/37610699/markers-for-major-complications-at-day-one-postoperative-in-fast-track-metabolic-surgery-updated-metabolic-checklist
#10
JOURNAL ARTICLE
J W H 't Hart, R Takken, C R C Hogewoning, L U Biter, J A Apers, H Zengerink, M Dunkelgrün, C Verhoef
INTRODUCTION: In fast-track metabolic surgery, the window to identify complications is narrow. Postoperative checklists can be useful tools in the decision-making of safe early discharge. The aim of this study was to evaluate the predictive value of a checklist used in metabolic surgery. METHODS: Retrospective data from June 2018 to January 2021 was collected on all patients that underwent metabolic surgery in a high-volume bariatric hospital in the Netherlands...
August 23, 2023: Obesity Surgery
https://read.qxmd.com/read/37488441/perioperative-optimization-and-profitability-pop-in-a-high-volume-bariatric-surgery-center
#11
JOURNAL ARTICLE
Lærke Alstrup, Katrine Stryhn, Claus Riber, Rakin Hadad, Jan Hvistendahl, Carsten Tollund, Steen B Haugaard, Peter Funch-Jensen
BACKGROUND: Currently, bariatric surgery is the most effective long-term treatment of obesity. Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the primary types of bariatric surgery performed worldwide. To minimize the risks of surgical complications and optimize cost-effectiveness, it is essential to develop fast-track protocols and patient logistics. At Aleris Hospitals in Denmark, a fast-track methodology in bariatric surgery has been implemented and continuously optimized over the last 15 years...
July 24, 2023: Surgical Endoscopy
https://read.qxmd.com/read/37262929/saliva-insulin-tracks-plasma-insulin-across-the-day-following-high-carbohydrate-and-low-carbohydrate-meals
#12
JOURNAL ARTICLE
Hossein Rafiei, Kosar Omidian, Courtney Rochelle Chang, Jonathan P Little
Non-invasive monitoring of insulin could hold promise to identify those with, or at risk for developing, insulin resistance. We aimed to examine saliva insulin responses across the day following high- and low-carbohydrate meals and evaluate if changes in saliva insulin might accurately reflect changes in plasma insulin. In two randomized crossover studies, young normal-weight men (NW; n=8; Study 1) and adults with overweight/obesity (OO; n=8; Study 2) completed two 9-h experimental trials in which the participants consumed isocaloric mixed high-carbohydrate (HC) or low-carbohydrate (LC) meals at 0, 3, and 6 h...
June 1, 2023: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/37199830/complications-in-patients-undergoing-laparoscopic-bariatric-surgery-in-an-erabs-optimized-high-volume-single-center-during-2020-and-2021
#13
JOURNAL ARTICLE
Katrine Stryhn, Lærke Alstrup, Claus Riber, Michael Ørting, Rakin Hadad, Jan Hvistendahl, Carsten Tollund, Niels Boye, Steen B Haugaard, Peter Funch-Jensen
PURPOSE: Complication rates after fast-track optimization in bariatric surgery are varying. The aim of this study was to identify short-term complications in patients undergoing laparoscopic sleeve gastrectomy (SG) in an ERABS (enhanced recovery after bariatric surgery) optimized setup. MATERIALS AND METHODS: This study is an observational analysis of a consecutive cohort of 1600 patients undergoing SG at an ERABS-optimized, private hospital during 2020 and 2021...
July 2023: Obesity Surgery
https://read.qxmd.com/read/37090325/spinopelvic-in-situ-fixation-and-early-mobilization-a-case-report-and-literature-review
#14
Ali Alshehri, Hosam Alrehaili, Sultan Batayyib, Abdullah Saeed, Mohammed S Alharthi, Reem Alasmari
Pelvic fractures with sacroiliac extension are significant and complicated orthopedic injuries that pose a challenge in management and favorable outcomes. A 50-year-old obese female presented after a motor vehicle accident with pelvic fracture lateral compression. The patient underwent anterior external fixation with a left sacroiliac screw (SIS) on the next day of admission and was kept in a non-weight-bearing state. During her hospital stay, she developed deep vein thrombosis (DVT) and was treated. During the follow-up on the sixth week, the patient was not complying with her immobilization instructions and was exposing the left lower limb to weight bearing...
March 2023: Curēus
https://read.qxmd.com/read/37076191/paediatric-obesity-evaluation-for-metabolic-susceptibility-poems
#15
JOURNAL ARTICLE
Daniel Chan, Cherie Chua, Carin Loh, Rehena Sultana, Rashida Farhad Vasanwala
INTRODUCTION: Our aim was to determine whether there are risk factors which increase the risk of developing dysglycemia in a child who has increased body mass index (BMI) (overweight/obese). RESEARCH DESIGN AND METHODS: This was a retrospective cohort study of 715 children who had increased BMI (overweight/obese). They presented to tertiary care at KK Women's and Children's Hospital, Singapore, for metabolic risk assessment. Subjects who had more than one oral glucose tolerance test were included in order to track and analyze risk factors associated with worsening glycemic status from a previously normal glucose tolerance, impaired fasting glucose, or impaired glucose tolerance (IGT) state...
April 2023: BMJ Open Diabetes Research & Care
https://read.qxmd.com/read/37034787/trends-in-health-behavior-at-an-afterschool-program-the-impact-of-covid-19-on-students-behavior
#16
Emily Yamron, Jee-Young Moon, Paul Meissner, Judith Wylie-Rosett, Viswanathan Shankar, Jessica Rieder
BACKGROUND: A minority of American youth meet CDC physical activity (PA) recommendations; children in the Bronx face additional structural barriers to engaging in PA. The B'N Fit Power expansion draws on pilot programming to increase the proportion of middle school students who engage in one hour of daily PA. The COVID-19 pandemic presented additional obstacles, including increased food insecurity and suspension of organized PA programming. This research aimed to evaluate differences in baseline target behavior attainment before and after the start of the COVID-19 pandemic to inform future programming to help children reduce their risk of obesity...
March 28, 2023: Research Square
https://read.qxmd.com/read/37029651/postoperative-day-1-discharge-after-robotic-totally-endoscopic-coronary-bypass-the-ultimate-in-enhanced-recovery-after-surgery
#17
JOURNAL ARTICLE
Sarah Nisivaco, Brooke Patel, Charocka Coleman, Hiroto Kitahara, Gianluca Torregrossa, Husam H Balkhy
OBJECTIVE: The benefits of Enhanced Recovery After Surgery (ERAS) protocols are being recognized in multiple surgical specialties, including following coronary bypass surgery to improve quality of care and decrease costs. We developed a fast-track discharge protocol for patients undergoing robotic totally endoscopic coronary bypass surgery (TECAB) to be discharged on postoperative day (POD) 1, the subjects of this study. METHODS: In a retrospective study of 720 patients undergoing robotic beating-heart TECAB over 8 years at our institution, 93 patients were selected for a fast-track POD1 discharge protocol...
April 8, 2023: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://read.qxmd.com/read/36927378/glp-1-gip-analogs-potential-impact-in-the-landscape-of-obesity-pharmacotherapy
#18
JOURNAL ARTICLE
Ryan A Lafferty, Peter R Flatt, Nigel Irwin
INTRODUCTION: Obesity is recognized as a major healthcare challenge. Following years of slow progress in discovery of safe, effective therapies for weight management, recent approval of the glucagon-like peptide 1 receptor (GLP-1R) mimetics, liraglutide and semaglutide, for obesity has generated considerable excitement. It is anticipated these agents will pave the way for application of tirzepatide, a highly effective glucose-dependent insulinotropic polypeptide receptor (GIPR), GLP-1R co-agonist, recently approved for management of type 2 diabetes mellitus...
March 28, 2023: Expert Opinion on Pharmacotherapy
https://read.qxmd.com/read/36741304/the-safety-of-immediate-extubation-and-factors-associated-with-delayed-extubation-in-cardiac-surgical-patients-receiving-fast-track-cardiac-anesthesia-an-integrative-review
#19
REVIEW
Raluca Tiganila, Carolyn McCoy, Robert Gilbert, James Raco
BACKGROUND: Early extubation (EE), within 8 h of cardiac surgery, is associated with improved resource utilization. Studies have demonstrated that for patients receiving low-dose, fast-track opioid cardiac anesthesia (FTCA) protocols, EE is as safe as conventional care. To date, it is unclear when the earliest timepoints for safe extubation might be. Additionally, some authors pointed out that certain patients receiving FTCA protocols frequently experience delays during extubation attempts...
2023: Canadian Journal of Respiratory Therapy: CJRT
https://read.qxmd.com/read/36728701/adolescent-blood-pressure-classification-curves-and-cardiometabolic-risk-factors-a-comparison-of-the-brazilian-and-american-references
#20
JOURNAL ARTICLE
Brenda M Medeiros, Thiago L N Da Silva, Katia V Bloch, Maria C C Kuschnir, Mariana Sbaraini, Beatriz D Schaan, Felipe V Cureau
BACKGROUND: The American Academy of Pediatrics (AAP) adolescent blood pressure (BP) percentiles were updated in 2017, and have been used as reference in Brazil since then. However, specific BP percentiles for Brazilian adolescents were recently proposed based on data from the Study of Cardiovascular Risk in Adolescents (ERICA). OBJECTIVES: To compare the prevalence of arterial hypertension according to each reference, as well as to assess the cardiometabolic risk associated with the reclassification by Brazilian BP percentiles...
December 28, 2022: Journal of Hypertension
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