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https://www.readbyqxmd.com/read/28446040/characteristics-of-socially-withdrawn-youth-in-france-a-retrospective-study
#1
Nicolas Chauliac, Audrey Couillet, Sophie Faivre, Nassima Brochard, Jean-Louis Terra
BACKGROUND: Poor social interactions have been recognized as a symptom since the beginnings of psychiatry. As far as socially withdrawn youth (SWY) are concerned, studies were mostly conducted on patients seeking care. Our psychiatric outreach team called Psymobile was able to reach SWY patients who were not seeking mental health care. AIMS: To identify the clinical and socio-demographic characteristics of SWY patients referred to our Psymobile unit. METHOD: We carried out a retrospective study on the records of patients aged 18-34 years, who were referred to Psymobile for 'withdrawal', between April 2012 and December 2015...
April 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28443993/work-accidents-and-self-esteem-of-nursing-professional-in-hospital-settings
#2
Sérgio Valverde Marques Dos Santos, Flávia Ribeiro Martins Macedo, Luiz Almeida da Silva, Zelia Marilda Rodrigues Resck, Denismar Alves Nogueira, Fábio de Souza Terra
OBJECTIVE: to analyze the occurrence of work accidents and the self-esteem of nurses in hospitals of a municipality of Minas Gerais. METHOD: descriptive-analytical and cross-sectional study developed with 393 nursing professionals from three hospitals of a municipality in southern Minas Gerais. The Rosenberg Self-Esteem Scale and a questionnaire to characterize the population and work accidents were used for data collection. Data analysis was performed using Person's chi-squared test, Fisher's exact test, Cronbach's alpha, odds ratio and logistic regression...
April 20, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28443970/permanent-education-actions-of-nurse-facilitators-at-a-nursing-education-centre
#3
Claudia Rosane Perico Lavich, Marlene Gomes Terra, Amanda de Lemos Mello, Michele Raddatz, Cristiane Trivisiol Arnemann
Objective: To identify actions of nurse facilitators of a permanent healthcare education centre of a teaching hospital. Methods: A single case study with a qualitative approach conducted with eight nurses from a hospital in the state of Rio Grande do Sul, Brazil. The data were generated through document analysis, systematic observation, and a focus group from April to September 2013. Results: The study produced the following categories: powerful strategies to promote permanent healthcare education actions from facilitating nurses and limitations for the development of these actions...
April 20, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28440612/association-between-xrcc1-and-wrn-as-genetic-markers-of-stability-and-susceptibility-to-cancer-in-patients-with-hiv-aids-and-cancer-a-cross-sectional-study
#4
Gabriel de Carvalho Maldonado, Orlando Nascimento Terra Júnior, Adriano Arnóbio, Guilherme Rohem Alfradique, Maria Helena Ornellas, Roberto Irineu da Silva, Dirce Bonfim de Lima
Background: HIV-induced immunodeficiency has been implicated as a key factor for risk of cancer. Neoplasia is considered to result from accumulation of damage to the genome. Polymorphisms in repair genes, such as the XRCC1 and WRN, have been associated with susceptibility to development of cancer in patients with HIV/AIDS. The aim of this study was to analyze the frequency of polymorphisms in XRCC1 (Arg399Gln) and WRN (Cys1367Arg) in patients with HIV/AIDS with or without cancer. Materials and Methods: Genotyping for analysis of polymorphisms was carried out by PCR (Polymerase Chain Reaction) and RFLP (Restriction Fragment Length Polymorphism)...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28440422/variable-terra-abundance-and-stability-in-cervical-cancer-cells
#5
Bong-Kyeong Oh, Ponnarath Keo, Jaeman Bae, Jung Hwa Ko, Joong Sub Choi
Telomeres are transcribed into long non-coding RNA, referred to as telomeric repeat-containing RNA (TERRA), which plays important roles in maintaining telomere integrity and heterochromatin formation. TERRA has been well characterized in HeLa cells, a type of cervical cancer cell. However, TERRA abundance and stability have not been examined in other cervical cancer cells, at least to the best of our knowledge. Thus, in this study, we measured TERRA levels and stability, as well as telomere length in 6 cervical cancer cell lines, HeLa, SiHa, CaSki, HeLa S3, C-33A and SNU-17...
April 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28435176/climate-shocks-and-rural-urban-migration-in-mexico-exploring-nonlinearities-and-thresholds
#6
Raphael J Nawrotzki, Jack DeWaard, Maryia Bakhtsiyarava, Jasmine Trang Ha
Adverse climatic conditions may differentially drive human migration patterns between rural and urban areas, with implications for changes in population composition and density, access to infrastructure and resources, and the delivery of essential goods and services. However, there is little empirical evidence to support this notion. In this study, we investigate the relationship between climate shocks and migration between rural and urban areas within Mexico. We combine individual records from the 2000 and 2010 Mexican censuses (n=683,518) with high-resolution climate data from Terra Populus that are linked to census data at the municipality level (n=2,321)...
January 2017: Climatic Change
https://www.readbyqxmd.com/read/28430813/phytoplankton-blooms-during-austral-summer-in-the-ross-sea-antarctica-driving-factors-and-trophic-implications
#7
Olga Mangoni, Vincenzo Saggiomo, Francesco Bolinesi, Francesca Margiotta, Giorgio Budillon, Yuri Cotroneo, Cristina Misic, Paola Rivaro, Maria Saggiomo
During the austral summer of 2014, an oceanographic cruise was conducted in the Ross Sea in the framework of the RoME (Ross Sea Mesoscale Experiment) Project. Forty-three hydrological stations were sampled within three different areas: the northern Ross Sea (RoME 1), Terra Nova Bay (RoME 2), and the southern Ross Sea (RoME 3). The ecological and photophysiological characteristics of the phytoplankton were investigated (i.e., size structure, functional groups, PSII maximum quantum efficiency, photoprotective pigments), as related to hydrographic and chemical features...
2017: PloS One
https://www.readbyqxmd.com/read/28423085/molecular-survey-of-anaplasma-platys-and-ehrlichia-canis-in-dogs-from-campo-grande-mato-grosso-do-sul-brazil
#8
Rodrigo Soares, Carlos Alberto Ramos, Thatianna Pedroso, Verônica Babo-Terra, Herbert Cleveland, Flábio DE Araújo
This study investigated the frequency of infection by Anaplasma platys and Ehrlichia canis in dogs submitted to animal health centers in Campo Grande, state of Mato Grosso do Sul, Brazil. E. canis and A. platys showed infection frequencies of 55.75% and 16.96%, respectively. The identity of the two species was confirmed by DNA sequencing.
January 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28419598/biological-traits-rather-than-environment-shape-detection-curves-of-large-vertebrates-in-neotropical-rainforests
#9
Thomas Denis, Cécile Richard-Hansen, Olivier Brunaux, Marie-Pierre Etienne, Stéphane Guitet, Bruno Hérault
Line transect surveys are widely used in neotropical rainforests to estimate the population abundance of medium- and large-sized vertebrates. The use of indices such as Encounter Rate has been criticized because the probability of animal detection may fluctuate due to the heterogeneity of environmental conditions among sites. In addition, the morphological and behavioral characteristics (biological traits) of species affect their detectability. In this study, we compared the extent to which environmental conditions and species' biological traits bias abundance estimates in terra firme rainforests in French Guiana...
April 17, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28412492/element-variability-in-lacustrine-systems-of-terra-nova-bay-antarctica-and-concentration-evolution-in-surface-waters
#10
Isabella Zelano, Mery Malandrino, Agnese Giacomino, Sandro Buoso, Eleonora Conca, Yann Sivry, Marc Benedetti, Ornella Abollino
Major, minor and trace elements were determined in freshwater of lacustrine systems in Terra Nova Bay, along Victoria Land coast, Antarctica, as well as in algae and mosses. The samples were collected during some of the sampling campaigns between 2007 and 2011 (and the one of 2002) within the framework of the Italian National Program of Research in Antarctica (PNRA). Data were processed with chemometric techniques. Results showed that elements typically considered as potential anthropogenic pollutants (e.g...
April 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/28409140/osteoid-osteoma-of-the-distal-clavicle
#11
Bernardo Barcellos Terra, Leandro Marano Rodrigues, David Victoria Hoffmann Padua, Tannous Jorge Sassine, José Maria Cavatte, Anderson De Nadai
The osteoid osteoma is a bone tumor that accounts for 10% of benign tumors. It was described in 1935 by Jaffe, as a tumor that affects the young adult population, with a predominance of males. This study aims to present a case of late diagnosis of a patient with osteoid osteoma of the distal clavicle region. Female patient, 44 years old, non-professional volleyball player, reported pain in the anterior and superior region of the shoulder girdle, specifically in the acromioclavicular joint, which worsened at night and had been treated for nine months as tendinitis of the rotator cuff and acromioclavicular joint arthritis...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28408926/male-hypogonadism-and-osteoporosis-the-effects-clinical-consequences-and-treatment-of-testosterone-deficiency-in-bone-health
#12
REVIEW
Gary Golds, Devon Houdek, Terra Arnason
It is well recognized that bone loss accelerates in hypogonadal states, with female menopause being the classic example of sex hormones affecting the regulation of bone metabolism. Underrepresented is our knowledge of the clinical and metabolic consequences of overt male hypogonadism, as well as the more subtle age-related decline in testosterone on bone quality. While menopause and estrogen deficiency are well-known risk factors for osteoporosis in women, the effects of age-related testosterone decline in men on bone health are less well known...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28392382/angiogenenic-effects-of-bplec-a-c-type-lectin-isolated-from-bothrops-pauloensis-snake-venom
#13
Letícia Eulalio Castanheira, Daiana Silva Lopes, Sarah Natalie Cirilo Gimenes, Simone Ramos Deconte, Bruno Antônio Ferreira, Patricia Terra Alves, Luiz Ricardo Goulart Filho, Tatiana Carla Tomiosso, Renata Santos Rodrigues, Kelly Aparecida Geraldo Yoneyama, Fernanda de Assis Araújo, Veridiana de Melo Rodrigues
The present work reports the effects of a C-type lectin (BpLec) isolated from Bothrops pauloensis snake venom upon in vitro and in vivo angiogenesis models. Initially, we noted that BpLec was not cytotoxic to endothelial cells (tEnd) in doses up to 40μg/mL, but lower doses (2.5μg/mL, 5μg/mL, 10μg/mL and 20μg/mL) reduced tEnd cells adhesion to some extracellular matrix proteins and inhibited the in vitro vessel formation in Matrigel assay stimulated by bFGF. β-galactosides (d-lactose, N-acetyl-d-galactosamine and d-galactose) at 400mM reversed the effect of BpLec on tEnd cells adhesion, whereas d-galactose (400mM) partially reversed BpLec property of inhibiting vessel formation by tEnd cells in Matrigel...
April 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28387154/production-of-polyhydroxyalkanoates-pha-using-sludge-from-different-wastewater-treatment-processes-and-the-potential-for-medical-and-pharmaceutical-applications
#14
Wai Lam, Yujie Wang, Pui Ling Chan, Shun Wan Chan, Yiu Fai Tsang, Hong Chua, Peter Hoi Fu Yu
In this study, seven strains of bacteria with polyhydroxyalkanoates (PHA)-producing ability (i.e. Bacillus cereus, Pseudomonas putida, Bacillus pumilus, Pseudomona huttiensis, Yersinia frederiksenii, Aeromonas ichthiosmia, and Sphingopyxis terrae) were isolated from various waste treatment plants in Hong Kong. Simultaneous wastewater treatment and PHA accumulation were successfully achieved in the bioreactors using isolated bacteria from different sludges. At the organic loading less than 13,000 ppm, more than 95% of chemical oxygen demand (COD) was removed by the isolated strains before the decrease of PHA accumulation...
April 20, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28377489/preclinical-activity-of-the-novel-anti-prolactin-receptor-prlr-antibody-drug-conjugate-regn2878-dm1-in-prlr-positive-breast-cancers
#15
Marcus P Kelly, Carlos Hickey, Sosina Makonnen, Sandra Coetzee, Sumreen Jalal, Yu Wang, Frank Delfino, Jing Shan, Terra B Potocky, Ishita Chatterjee, Julian Andreev, Arthur Kunz, Christopher D'Souza, Jason T Giurleo, Thomas Nittoli, Pamela A Trail, Gavin Thurston, Jessica R Kirshner
The Prolactin Receptor (PRLR) is a type 1 cytokine receptor that is expressed in a subset of breast cancers and may contribute to its pathogenesis. It is relatively over-expressed in ~25% of human breast tumors while expressed at low levels in some normal human tissues including the mammary gland. We developed an anti-PRLR antibody-drug conjugate (ADC), to target PRLR positive breast cancer. REGN2878-DM1 is comprised of a fully human high affinity function-blocking anti-PRLR IgG1 antibody (REGN2878) conjugated via a non-cleavable SMCC linker to the cytotoxic maytansine derivative DM1...
April 4, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28374892/in-vitro-adult-astrocytes-are-derived-from-mature-cells-and-reproduce-in-vivo-redox-profile
#16
Débora Guerini Souza, Bruna Bellaver, Silvia Resende Terra, Fatima Costa Rodrigues Guma, Diogo Onofre Souza, André Quincozes-Santos
Astrocytes are versatile cells involved in synaptic information processing, energy metabolism, redox homeostasis, inflammatory response and structural support of the brain. Recently, we established a routine protocol of cultured astrocytes derived from adult and aged Wistar rats, which present several different responses compared to newborn astrocytes, commonly used to characterize the role of the astrocytes in the central nervous system. Previous studies hypothesized that astrocyte cultures prepared from adult animals derive from immature precursors present in the adult tissue throughout life...
April 4, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28372498/innate-immune-function-and-organ-failure-recovery-in-adults-with-sepsis
#17
Aline B Maddux, Terra D Hiller, Katherine H Overdier, Laura L Pyle, Ivor S Douglas
PURPOSE: Sepsis stimulates pro- and anti-inflammatory immune responses. The innate immune response is critical to organ injury repair. We tested for an association between innate immune function and organ function recovery in a prospective cohort of immune-competent adults with sepsis. METHODS: We conducted a prospective observational cohort study enrolling immune-competent adults with sepsis. We tested innate immune function by quantification of lipopolysaccharide (LPS)-stimulated tumor necrosis factor (TNF) α production capacity in whole blood samples on hospital days 1, 4, and 6...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28372367/fast-piezoelectric-valve-offering-controlled-gas-injection-in-magnetically-confined-fusion-plasmas-for-diagnostic-and-fuelling-purposes
#18
M Griener, O Schmitz, K Bald, D Bösser, M Cavedon, P De Marné, T Eich, G Fuchert, A Herrmann, A Kappatou, T Lunt, V Rohde, B Schweer, M Sochor, U Stroth, A Terra, E Wolfrum
In magnetically confined fusion plasmas controlled gas injection is crucial for plasma fuelling as well as for various diagnostic applications such as active spectroscopy. We present a new, versatile system for the injection of collimated thermal gas beams into a vacuum chamber. This system consists of a gas pressure chamber, sealed by a custom made piezo valve towards a small capillary for gas injection. The setup can directly be placed inside of the vacuum chamber of fusion devices as it is small and immune against high magnetic fields...
March 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28370365/monocytosis-in-polycythemia-vera-clinical-and-molecular-correlates
#19
Daniela Barraco, Sonia Cerquozzi, Naseema Gangat, Mrinal M Patnaik, Terra Lasho, Christy Finke, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Ayalew Tefferi
Monocytosis (absolute monocyte count, AMC ≥1 x 10(9) /L) might accompany a spectrum of myeloid neoplasms, other than chronic myelomonocytic leukemia (CMML). In the current study, we examined the prevalence, laboratory and molecular correlates, and prognostic relevance of monocytosis in polycythemia vera (PV). Among 267 consecutive patients with World Health Organization (WHO)-defined PV, 55 (21%) patients displayed an AMC of ≥1 x 10(9) /L and 18 (7%) an AMC of ≥1.5 x 10(9) /L. In general, PV patients with monocytosis were significantly older and displayed higher frequencies of leukocytosis (81% vs 50% at AMC ≥1 x 10(9) /L) and TET2/SRSF2 mutations (57%/29% vs 19%/1% at AMC≥1...
March 28, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28369998/the-importance-of-hydraulic-architecture-to-the-distribution-patterns-of-trees-in-a-central-amazonian-forest
#20
Luiza H M Cosme, Juliana Schietti, Flávia R C Costa, Rafael S Oliveira
Species distributions and assemblage composition may be the result of trait selection through environmental filters. Here, we ask whether filtering of species at the local scale could be attributed to their hydraulic architectural traits, revealing the basis of hydrological microhabitat partitioning in a Central Amazonian forest. We analyzed the hydraulic characteristics at tissue (anatomical traits, wood specific gravity (WSG)), organ (leaf area, specific leaf area (SLA), leaf area : sapwood area ratio) and whole-plant (height) levels for 28 pairs of congeneric species from 14 genera restricted to either valleys or plateaus of a terra-firme forest in Central Amazonia...
March 29, 2017: New Phytologist
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