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https://www.readbyqxmd.com/read/29627817/quantitative-fibronectin-to-help-decision-making-in-women-with-symptoms-of-preterm-labour-quids-part-1-individual-participant-data-meta-analysis-and-health-economic-analysis
#1
Sarah J Stock, Lisa M Wotherspoon, Kathleen A Boyd, Rachel K Morris, Jon Dorling, Lesley Jackson, Manju Chandiramani, Anna L David, Asma Khalil, Andrew Shennan, Victoria Hodgetts Morton, Tina Lavender, Khalid Khan, Susan Harper-Clarke, Ben W Mol, Richard D Riley, John Norrie, Jane E Norman
INTRODUCTION: The aim of the QUIDS study is to develop a decision support tool for the management of women with symptoms and signs of preterm labour, based on a validated prognostic model using quantitative fetal fibronectin (qfFN) concentration, in combination with clinical risk factors. METHODS AND ANALYSIS: The study will evaluate the Rapid fFN 10Q System (Hologic, Marlborough, Massachusetts) which quantifies fFN in a vaginal swab. In part 1 of the study, we will develop and internally validate a prognostic model using an individual participant data (IPD) meta-analysis of existing studies containing women with symptoms of preterm labour alongside fFN measurements and pregnancy outcome...
April 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29626722/a-qualitative-study-of-nulliparous-women-s-decision-making-on-mode-of-delivery-under-china-s-two-child-policy
#2
Chunyi Gu, Xinli Zhu, Yan Ding, Setterberg Simone, Xiaojiao Wang, Hua Tao, Yu Zhang
OBJECTIVE: To explore nulliparous women's perceptions of decision making regarding mode of delivery under China's two-child policy. DESIGN: Qualitative descriptive design with in-depth semi-structured interviews. SETTING: Postnatal wards at a tertiary specialized women's hospital in Shanghai, China. PARTICIPANTS: 21 nulliparous women 2-3 days postpartum were purposively sampled until data saturation. METHODS: In-depth semi-structured interviews were conducted between October 8th, 2015 and January 31st, 2016...
March 20, 2018: Midwifery
https://www.readbyqxmd.com/read/29621303/time-dependent-regulation-of-morphological-changes-and-cartilage-differentiation-markers-in-the-mouse-pubic-symphysis-during-pregnancy-and-postpartum-recovery
#3
Bianca Gazieri Castelucci, Sílvio Roberto Consonni, Viviane Souza Rosa, Lucimara Aparecida Sensiate, Paula Cristina Rugno Delatti, Lúcia Elvira Alvares, Paulo Pinto Joazeiro
Animal models commonly serve as a bridge between in vitro experiments and clinical applications; however, few physiological processes in adult animals are sufficient to serve as proof-of-concept models for cartilage regeneration. Intriguingly, some rodents, such as young adult mice, undergo physiological connective tissue modifications to birth canal elements such as the pubic symphysis during pregnancy; therefore, we investigated whether the differential expression of cartilage differentiation markers is associated with cartilaginous tissue morphological modifications during these changes...
2018: PloS One
https://www.readbyqxmd.com/read/29614445/exploring-full-cervical-dilatation-caesarean-sections-a-retrospective-cohort-study
#4
Edward M A Corry, Meenakshi Ramphul, Ann M Rowan, Ricardo Segurado, Rhona M Mahony, Declan P Keane
BACKGROUND: The rate of caesarean sections at full cervical dilatation with their high risk of morbidity continues to rise mirroring the overall increase in caesarean section rates internationally. OBJECTIVES: The objectives of this study were to determine the rate of full dilatation caesarean section in a tertiary referral unit and evaluate key labour, maternal and fetal factors potentially linked to those deliveries. We also assessed maternal and fetal morbidity at full dilatation sections...
March 20, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29608659/long-term-impact-of-oral-azithromycin-taken-by-gambian-women-during-labour-on-prevalence-and-antibiotic-susceptibility-of-s-pneumoniae-and-s-aureus-in-their-infants-follow-up-of-a-randomized-clinical-trial
#5
Abdoulie Bojang, Bully Camara, Isatou Jagne Cox, Claire Oluwalana, Kodou Lette, Effua Usuf, Christian Bottomley, Benjamin P Howden, Umberto D'Alessandro, Anna Roca
Background: Oral azithromycin given to women in labour decreases maternal and neonatal bacterial carriage but increases azithromycin resistant bacteria during at least 4 weeks following the intervention. We assessed the prevalence of bacterial carriage and azithromycin resistance 12 months after treatment among study infants. Methods: Nasopharyngeal swabs (NPS) were collected between November 2014 and May 2015 from children 11-13 months old whose mothers had received azithromycin or placebo during labour...
March 28, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29594003/snake-bite-in-third-trimester-of-pregnancy-with-systemic-envenomation-and-delivery-of-a-live-baby-in-a-low-resource-setting-a-case-report
#6
Adebayo A Adewole, Osadolor A Ugiagbe, Temitope G Onile, Gabriel A Joseph, Oluwamayowa D Kassim, Patricia F Medupin, Abiodun S Adeniran
Background: Snake bite in the third trimester of pregnancy with late presentation, systemic envenomation; disseminated intravascular coagulopathy and delivery of a live neonate is uncommon in a low resource setting. Case: We present a 22 year old unbooked Gravida 3 Para 1+ 1 1alive lentiviral positive woman at 32 weeks gestation with snake bite, leg swelling, vaginal bleeding and labour pains. At presentation, there were anemia, tachycardia, hypotension; a gravid uterus with a single fetus in longitudinal lie, cephalic presentation, regular fetal heart rate and cervical dilatation of 3 cm...
October 2017: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29592984/a-rare-cause-of-postpartum-headache
#7
Nayantara Bijral, Imran Qureshi, Aisha Hameed
Postpartum women can develop headache, and their assessment requires a thorough and multidisciplinary approach. If the headache is unresponsive to treatment and accompanied by neurological deficit, neuroimaging needs to be undertaken to rule out other life-threatening causes.1 We present a case of 35-year-old woman with pre-eclampsia and diet-controlled gestational diabetes mellitus, who had normal vaginal delivery at 40 weeks. She had an epidural analgesia for pain relief during labour, but had inadvertent dural puncture during the procedure and developed headache 24 hours after delivery...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29589650/relaxation-techniques-for-pain-management-in-labour
#8
REVIEW
Caroline A Smith, Kate M Levett, Carmel T Collins, Mike Armour, Hannah G Dahlen, Machiko Suganuma
BACKGROUND: Many women would like to avoid pharmacological or invasive methods of pain management in labour and this may contribute to the popularity of complementary methods of pain management. This review examined currently available evidence on the use of relaxation therapies for pain management in labour. This is an update of a review first published in 2011. OBJECTIVES: To examine the effects of mind-body relaxation techniques for pain management in labour on maternal and neonatal well-being during and after labour...
March 28, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29587540/risk-of-recurrent-shoulder-dystocia-are-we-any-closer-to-prediction
#9
Shadha Al-Hawash, Clare L Whitehead, Dan Farine
OBJECTIVE: To determine the incidence and risk factors for recurrent shoulder dystocia in women. METHODS: We searched Medline, Pubmed, Embase, and CINAHL for relevant articles in English and French from 1980 to February 2018 that described risks of recurrent shoulder dystocia undergoing a trial of labour in subsequent pregnancies. A total of 684 articles were found, of which 13 were included as they met criteria. We extracted data on study characteristics, incidence of recurrent shoulder dystocia, degree of neonatal injury, and presence of known risk factors...
March 27, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29580256/utilization-of-institutional-delivery-service-and-associated-factors-among-mothers-in-north-west-ethiopian
#10
Solomon Weldemariam, Amare Kiros, Mengistu Welday
OBJECTIVE: The aim of this study was to assess institutional delivery and its associated factors in Benishangul-Gumez region, North-West of Ethiopia. The data were obtained at community level in a single survey within 1 month and there is no continuation of this study or previously published part elsewhere. RESULTS: Among the 428 eligible respondents recruited for this study, 427 of them responded completely to the interview, giving a response rate of 99.8%. Of the total (427) respondents, 51...
March 27, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29571040/different-concentration-of-human-cord-blood-hmgb1-according-to-delivery-and-labour-a-pilot-study
#11
G D'Angelo, L Marseglia, R Granese, A Di Benedetto, A Giacobbe, P Impellizzeri, A Alibrandi, E Ferro, A Palmara, S Manti, T Arrigo, C Salpietro, G Buonocore, R J Reiter, E Gitto
OBJECTIVE: Oxidative stress is involved in several maternal conditions characterized both by an increase in free radicals synthesis and a parallel decrease in the antioxidant activity. Parturition induces considerable oxidative stress and many inflammatory mediators, among which HMGB1, are involved from the beginning of pregnancy to the birth of the infant. We evaluated serum cord blood HMGB1 levels in a population of neonates to investigate correlation with mode of delivery, as well as the influence of labour...
March 20, 2018: Cytokine
https://www.readbyqxmd.com/read/29570453/anencephaly-and-obstetric-outcome-beyond-the-age-of-viability
#12
Sawsan Al-Obaidly, Jis Thomas, Mahmoud Abu Jubara, Abdullah Al Ibrahim, Mariam Al-Belushi, Najah Saleh, Zeena Al-Mansouri, Najat Khenyab
OBJECTIVE: To review the obstetric impact and natural history of anencephalic pregnancies beyond the age of viability. STUDY DESIGN: A retrospective chart review of all cases with a prenatal diagnosis of anencephaly who delivered after 24 weeks' gestation during the period 1990 until 2016. Obstetric outcomes including mode of delivery, live births, shoulder dystocia, antepartum haemorrhage (APH), postpartum haemorrhage (PPH) and uterine rupture were studied. RESULTS: A total of 42 cases were studied...
March 23, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29566729/intrauterine-resuscitation-during-the-second-stage-of-term-labour-by-maternal-hyperoxygenation-versus-conventional-care-study-protocol-for-a-randomised-controlled-trial-interest-o2
#13
Lauren M Bullens, Alexandra D J Hulsenboom, Suzanne Moors, Rohan Joshi, Pieter J van Runnard Heimel, M Beatrijs van der Hout-van der Jagt, Edwin R van den Heuvel, S Guid Oei
BACKGROUND: Perinatal asphyxia is, even in developed countries, one the major causes of neonatal morbidity and mortality. Therefore, if foetal distress during labour is suspected, one should try to restore foetal oxygen levels or aim for immediate delivery. However, studies on the effect of intrauterine resuscitation during labour are scarce. We designed a randomised controlled trial to investigate the effect of maternal hyperoxygenation on the foetal condition. In this study, maternal hyperoxygenation is induced for the treatment of foetal distress during the second stage of term labour...
March 23, 2018: Trials
https://www.readbyqxmd.com/read/29566566/combination-of-three-dimensional-ultrasound-measurement-of-foetal-adrenal-gland-enlargement-and-placental-alpha-microglobulin-1-for-the-prediction-of-the-timing-of-delivery-within-seven-days-in-women-with-threatened-preterm-labour-and-preterm-labour
#14
Monchai Santipap, Vorapong Phupong
The aim of this study was to predict the timing of delivery within seven days in singleton pregnant women with threatened preterm labour and preterm labour by using a three-dimensional (3D) ultrasound measurement of foetal adrenal gland volume enlargement, a foetal zone enlargement and cervicovaginal placental alpha microglobulin-1 (PAMG-1) test. This prospective cohort study included singleton pregnant women at 22-36+6  weeks of gestation who presented with threatened preterm labour and with preterm labour...
March 23, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29566564/association-between-preterm-labour-and-pelvic-floor-muscle-function
#15
Turhan Aran, Ipek Pekgöz, Hasan Bozkaya, Mehmet A Osmanagaoglu
We hypothesised that the pressure on the cervix increases with advancing gestation and it may lead to a cervical shortening and cause preterm labour in women with weak pelvic floor muscles. The aim of this prospective study was to measure vaginal resting pressure and pelvic floor muscle strength in the first trimester of pregnancy and to investigate their effects on labour. A study was conducted on the pregnant women with a low risk for preterm birth. The pelvic floor muscle strength and vaginal resting pressure were assessed in 320 pregnant women at their first trimester with a vaginal pressure measurement device...
March 23, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29565195/influence-of-maternal-factors-and-mode-of-induction-on-labour-outcomes-a-pragmatic-retrospective-cohort-study
#16
L Jonker, F Memon
Since recent research indicates that other modalities are at a minimum non-inferior to the NICE-recommended hormonal agent prostaglandin E2 (PGE2 ), a retrospective cohort study was conducted on 1971 consecutively induced singleton pregnancies. Multinominal regression analysis showed that the odds ratio (OR) for vaginal delivery with balloon-mediated labour induction (84% vaginal deliveries; OR 1.6; 95% CI 0.7-3.5) is similar to the PGE2 agents propess (81%; OR 1.2; 95% CI 0.68-1.98) and prostin (79%; OR 0...
March 22, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29565193/unintended-hysterotomy-extension-during-caesarean-delivery-risk-factors-and-maternal-morbidity
#17
Lauren E Giugale, Sara Sakamoto, Jonathan Yabes, Shannon L Dunn, Elizabeth E Krans
We conducted an observational retrospective cohort study to evaluate the risk factors and the maternal morbidity associated with unintended extensions of the hysterotomy during caesarean delivery. We evaluated 2707 women who underwent low-transverse caesarean deliveries in 2011 at an academic, tertiary-care hospital. Hysterotomy extensions were identified through operative reports. Of the 2707 caesarean deliveries, 392 (14.5%) had an unintended hysterotomy extension. On the multivariable regression modelling, neonatal weight (OR 1...
March 22, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29559431/findings-and-methodological-quality-of-systematic-reviews-focusing-on-acupuncture-for-pregnancy-related-acute-conditions
#18
Thaís Romera Bergamo, Carolina de Oliveira Cruz Latorraca, Daniela Vianna Pachito, Ana Luiza Cabrera Martimbianco, Rachel Riera
INTRODUCTION: Major concerns regarding the use of medication during pregnancy justify the need for safer interventions. Acupuncture is an emerging alternative for several clinical conditions during this period. The objective of this study is to summarise evidence derived from systematic reviews (SRs) focusing on acupuncture for pregnancy-related acute conditions. METHODS: Review of SRs. A systematic literature search was carried out in several electronic databases, aiming to include all SRs assessing the effects of acupuncture for acute conditions during pregnancy...
March 20, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/29557079/perinatal-outcomes-of-women-diagnosed-with-attention-deficit-hyperactivity-disorder-an-australian-population-based-cohort-study
#19
Alison S Poulton, Bruce Armstrong, Ralph K Nanan
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is common and may require treatment in adulthood. We aimed to investigate the treatment patterns and perinatal outcomes of women with any history of stimulant treatment for ADHD. METHODS: We used health records of the New South Wales (NSW, Australia) population to compare perinatal outcomes of women treated with stimulants (dexamphetamine or methylphenidate) for ADHD from 1982 to 2012 who gave birth between 1994 and 2012, with perinatal outcomes of women with no known ADHD or stimulant treatment (comparison cohort)...
March 19, 2018: CNS Drugs
https://www.readbyqxmd.com/read/29555546/specific-situations
#20
Gaëlle Cheisson, Sophie Jacqueminet, Emmanuel Cosson, Carole Ichai, Anne-Marie Leguerrier, Bogdan Nicolescu-Catargi, Alexandre Ouattara, Igor Tauveron, Paul Valensi, Dan Benhamou
Ambulatory surgery can be carried out in diabetic patients. By using a strict organisational and technical approach, the risk of glycaemic imbalance is minimised, allowing the patients to return to their previous way of life more quickly. Taking into account the context of ambulatory surgery, with a same day discharge, the aims are to minimise the changes to antidiabetic treatment, to maintain adequate blood sugar control and to resume oral feeding as quickly as possible. The preoperative evaluation is the same as for a hospitalised patient and recent glycaemic control (HbA1c) is necessary...
March 16, 2018: Anaesthesia, Critical Care & Pain Medicine
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