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https://www.readbyqxmd.com/read/29452395/mini-extracorporeal-circulation-technology-conventional-bypass-and-prime-displacement-in-isolated-coronary-and-aortic-valve-surgery-a-propensity-matched-in-hospital-and-survival-analysis
#1
Priyadharshanan Ariyaratnam, Lindsay A Mclean, Alexander Cale, Mubarak A Chaudhry, Ajith Vijayan, Neil Richards, Martin A Jarvis, Yama Haqzad, Dumbor Ngaage, Michael E Cowen, Mahmoud Loubani
OBJECTIVES: Conventional cardiopulmonary bypass is the most commonly used means of artificial circulation in cardiac surgery. However, it suffers from the effects of haemodilution and activation of inflammatory/coagulation cascades. Prime displacement (PD) can offset haemodilution and Mini-Extracorporeal Technology (MIECT) can offset both. So far, no study has compared all of these modalities together; hence, we compared the outcomes of these 3 modalities at our institution. METHODS: This was a retrospective analysis of our cardiac surgical database...
February 14, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29451448/donor-nerve-axotomy-and-axonal-regeneration-after-end-to-side-neurorrhaphy-in-a-rodent-model
#2
Shiwei Wang, Diya Su, Jing Li, Dezhi Li, Hong Wan, Michael Schumacher, Song Liu
OBJECTIVE In this study, the authors used a surgical model of end-to-side neurorrhaphy between a nerve graft and a donor tibial nerve in adult rats to investigate the optimal conditions for axonal regeneration induced by the donor nerve. They also assessed the importance of a more favorable pathway using a predegenerated nerve graft to attract regenerating axons to regrow into the graft and then directing and improving their growth toward the target in comparison with results obtained with a fresh nerve graft...
February 16, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29447307/clinical-and-histologic-evaluations-of-immediately-placed-sla-dental-implants
#3
Myron Nevins, Stefano Parma-Benfenati, Cosmin Sava, Catalin Sava, Franco Quinti, Primo Galletti, Gerardo Mendoza-Azpur, Erik Valdivia, Yong-Han Koo, David M Kim
The goal of this investigation was to evaluate the bone-to-implant contact (BIC) of dental implants placed into fresh extraction sockets without pre-existing periapical pathology. When the extraction sites exhibited a gap distance of > 2 mm, autogenous bone harvested from surrounding surgical sites was grafted to fill that gap with no barrier membranes. All implants were clinically stable and successful at 6 months postoperative. The histologic examination demonstrated an average of 66.2% BIC for all five immediately placed dental implants...
March 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29445875/interference-screw-insertion-angle-has-no-effect-on-graft-fixation-strength-for-insertional-achilles-tendon-reconstruction
#4
Ziying Wu, Hongyun Li, Shiyi Chen, Kui Ma, Shengkun Li, Peng Zhang, Yinghui Hua
PURPOSE: To compare the effect of two interference screw insertion angles on the biomechanical properties of the insertional Achilles tendon (IAT) reconstruction. METHODS: Nine matched pairs of fresh-frozen human cadaveric Achilles tendon specimens were randomized to two groups with interference screw insertion angles of 60° and 120°. The IAT reconstruction was performed by fixing the graft tendon with the interference screw. Each specimen was loaded to failure...
February 14, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29431027/a-controlled-trial-of-sheng-yu-tang-for-post-hematopoietic-stem-cell-transplantation-leukemia-patients-a-proposed-protocol-and-insights-from-a-preliminary-pilot-study
#5
Tom Fleischer, Tung-Ti Chang, Jen-Huai Chiang, Hung-Rong Yen
Hematopoietic stem cell transplantation has become a well-established treatment for hematologic disorders including acute leukemia. However, long-term survival rates following this procedure are still extremely low, due to posttransplantation relapse, infections, and graft-versus-host disease. We propose that adjunctive Chinese herbal medicine may benefit posttransplantation patients. In preparation for a randomized clinical trial, we conducted a pilot trial. Methods and Analysis: Between September 2015 and June 2017, 18 patients were consecutively enrolled at China Medical University Hospital and followed for up to 1 year...
February 1, 2018: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29424428/volatile-composition-of-carignan-noir-wines-from-ungrafted-and-grafted-onto-pa%C3%A3-s-vitis-vinifera-l-grapevines-from-ten-wine-growing-sites-in-maule-valley-chile
#6
G Gutiérrez-Gamboa, T Garde-Cerdán, M Carrasco-Quiroz, E P Pérez-Álvarez, A M Martínez-Gil, M Del Alamo-Sanza, Y Moreno-Simunovic
BACKGROUND: Carignan noir is one of the minor and ancient varieties from the Chilean wine scenario, which has had a resurgence due to its rediscovered oenological potential when cultivated under the conditions of the interior dryland area. Under these growing conditions Carignan noir wines stand out as fruit driven and fresh when compared to those coming from other growing areas. On the other hand, it is well known that wine aroma composition depends mainly on variety, viticultural management, and winemaking...
February 9, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29416215/a-difference-in-bleeding-and-use-of-blood-and-blood-products-in-patients-who-were-preoperatively-on-aspirin-or-dual-antiplatelet-therapy-before-coronary-artery-bypass-grafting
#7
Slavenka Straus, Ilirijana Haxhibeqiri-Karabdic, Sanja Granov Grabovica, Nermir Granov
Background: Postoperative bleeding in patients who underwent elective coronary artery bypass surgery (CABG) may increase due to preoperative anticoagulant therapy indicative of their disease - acute coronary syndrome or implanted coronary artery stent. Increased bleeding in many cases requires the use of blood and blood derivatives, and sometimes even reoperation. Their use poses the risk of complications, may extend the hospitalization. Methods: Our observation retrospective study included 131 patients, 41 treated with aspirin and 90 treated with aspirin and clopidogrel...
February 2018: Medical Archives
https://www.readbyqxmd.com/read/29395551/quantitative-assessment-of-the-coracoacromial-and-the-coracoclavicular-ligaments-with-3-dimensional-mapping-of-the-coracoid-process-anatomy-a-cadaveric-study-of-surgically-relevant-structures
#8
Jorge Chahla, Daniel Cole Marchetti, Gilbert Moatshe, Márcio B Ferrari, George Sanchez, Alex W Brady, Jonas Pogorzelski, George F Lebus, Peter J Millett, Robert F LaPrade, Matthew T Provencher
PURPOSE: To perform a quantitative anatomic evaluation of the (1) coracoid process, specifically the attachment sites of the conjoint tendon, the pectoralis minor, the coracoacromial ligament (CAL), and the coracoclavicular (CC) ligaments in relation to pertinent osseous and soft tissue landmarks; (2) CC ligaments' attachments on the clavicle; and (3) CAL attachment on the acromion in relation to surgically relevant anatomic landmarks to assist in planning of the Latarjet procedure, acromioclavicular (AC) joint reconstructions, and CAL resection distances avoiding iatrogenic injury to surrounding structures...
January 24, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29392885/ex-vivo-expansion-of-cd34-cd90-cd49f-hematopoietic-stem-and-progenitor-cells-from-non-enriched-umbilical-cord-blood-with-azole-compounds
#9
Sudipto Bari, Qixing Zhong, Xiubo Fan, Zhiyong Poon, Alvin Soon Tiong Lim, Tse Hui Lim, Niraja Dighe, Shang Li, Gigi Ngar Chee Chiu, Christina Li Lin Chai, William Ying Khee Hwang
Umbilical cord blood (UCB) transplants in adults have slower hematopoietic recovery compared to bone marrow (BM) or peripheral blood (PB) stem cells mainly due to low number of total nucleated cells and hematopoietic stem and progenitor cells (HSPC). As such in this study, we aimed to perform ex vivo expansion of UCB HSPC from non-enriched mononucleated cells (MNC) using novel azole-based small molecules. Freshly-thawed UCB-MNC were cultured in expansion medium supplemented with small molecules and basal cytokine cocktail...
February 2, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29383502/influences-of-different-lower-cervical-bone-graft-heights-on-the-size-of-the-intervertebral-foramen-multiple-planar-dynamic-measurements-with-laser-scanning
#10
Rui Yang, Mengjun Ma, Lin Huang, Jichao Ye, Yong Tang, Peng Wang, Dezhen Yin, Keng Chen, Weiping Li, Huiyong Shen
The aim of this study is to evaluate the influences of different bone graft heights on the size of the intervertebral foramen, which will help determine the optimal graft height in clinical practice. Six fresh adult cadavers were used, with the C5-C6 vertebral column segment defined as the functional spinal unit (FSU). After discectomy, the C5/6 intervertebral height was set as the baseline height (normal disc height). We initially used spiral computed tomography (CT) to scan and measure the middle area of the intervertebral foramen when at the baseline height...
January 30, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29382209/distal-clavicular-osteochondral-autograft-augmentation-for-glenoid-bone-loss-a-comparison-of-radius-of-restoration-versus-latarjet-graft
#11
Adam Kwapisz, Kelly Fitzpatrick, Jay B Cook, George S Athwal, John M Tokish
BACKGROUND: Bone loss in shoulder instability is a well-recognized cause of failure after stabilization surgery. Many approaches have been described to address glenoid bone loss, including coracoid transfer. This transfer can be technically difficult and has been associated with high complication rates. An ideal alternative to coracoid transfer would be an autologous source of fresh osteochondral graft with enough surface area to replace significant glenoid bone loss. The distal clavicle potentially provides such a graft source that is readily available and low-cost...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29380749/injectable-hydrogels-of-optimized-acellular-nerve-for-injection-in-the-injured-spinal-cord
#12
Robert Chase Cornelison, Elisa Gonzalez-Rothi, Stacy L Porvasnik, Steven M Wellman, James H Park, David D Fuller, Christine E Schmidt
Spinal cord injury (SCI) affects a quarter million individuals in the United States, and there is currently no clinical treatment. Both fresh and acellular peripheral nerve grafts can induce spinal axon regeneration and support functional recovery in experimental injury models. Nonetheless, a scaffold that can be injected into a spinal contusion would be far less invasive to apply. We aimed to develop the first injectable acellular nerve graft for promoting repair after contusion SCI. Approach: We report a method to enzymatically solubilize optimized acellular (OA) nerve - a decellularized peripheral nerve graft developed in our laboratory and currently used clinically - to obtain an injectable solution that undergoes thermal gelation under physiological conditions...
January 30, 2018: Biomedical Materials
https://www.readbyqxmd.com/read/29370240/a-histological-examination-of-spinal-reconstruction-using-a-frozen-bone-autograft
#13
Kazuya Shinmura, Hideki Murakami, Satoru Demura, Satoshi Kato, Katsuhito Yoshioka, Hiroyuki Hayashi, Kei Inoue, Takashi Ota, Noriaki Yokogawa, Takayoshi Ishii, Takashi Igarashi, Hiroyuki Tsuchiya
Our aim was to compare the process of bone formation after reconstruction of the vertebral body using a titanium cage with either a liquid nitrogen-treated (frozen) bone autograft or non-treated fresh bone autograft. Twelve canine beagles underwent anterior reconstruction of the 5th lumbar vertebrae using a titanium cage and bone autograft. Bone formation was compared across four experimental groups: fresh bone autograft groups, with animals sacrificed at either 8 or 16 weeks post-reconstruction, and liquid nitrogen-treated (frozen) bone autograft groups, with animals again sacrificed at either 8 or 16 weeks post-reconstruction...
2018: PloS One
https://www.readbyqxmd.com/read/29369990/effect-of-cryopreservation-on-human-adipose-tissue-and-isolated-stromal-vascular-fraction-cells-in-vitro-and-in-vivo-analyses
#14
Fabiana Zanata, Annie Bowles, Trivia Frazier, J Lowry Curley, Bruce A Bunnell, Xiying Wu, James Wade, Ram Devireddy, Jeffrey M Gimble, Lydia Masako Ferreira
BACKGROUND: Adipose tissue is a source of adipose-derived stromal/stem cells for tissue engineering and reconstruction and a tissue source for fat grafts. Although liposuction is a simple procedure for the harvest of adipose tissue, the repetition of this surgical intervention can cause adverse effects to the patient and can be a limiting factor for immediate use. Cryopreservation can avoid the morbidity associated with repetitive liposuction, allowing the use of stored tissue after the initial harvest procedure...
February 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29369378/heat-transfer-analysis-and-resolution-quantification-of-active-dynamic-thermography-through-human-skin
#15
Nicholas J Prindeze, Yvette V L Mann, Tony G Feric, Timothy R Currie, Bonnie C Carney, Lauren T Moffatt, Murray H Loew, Jeffrey W Shupp
OBJECTIVES: Active dynamic thermography (ADT) is a non-contact imaging technique that characterizes non-homogeneities in thermal conductance through objects as a response to applied energy stimulus. The aim of this study was to (i) develop a heat transfer model to define the relationship between thermal stimulation and resolution and (ii) empirically quantify the resolution an ADT imaging system can detect through a range of depths of human skin. MATERIALS AND METHODS: A heat transfer model was developed to describe a thermally non-conductive object below a sheet of skin...
January 25, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29360772/thermoreversibly-cross-linked-epm-rubber-nanocomposites-with-carbon-nanotubes
#16
Lorenzo Massimo Polgar, Francesco Criscitiello, Machiel van Essen, Rodrigo Araya-Hermosilla, Nicola Migliore, Mattia Lenti, Patrizio Raffa, Francesco Picchioni, Andrea Pucci
Conductive rubber nanocomposites were prepared by dispersing conductive nanotubes (CNT) in thermoreversibly cross-linked ethylene propylene rubbers grafted with furan groups (EPM-g-furan) rubbers. Their features were studied with a strong focus on conductive and mechanical properties relevant for strain-sensor applications. The Diels-Alder chemistry used for thermoreversible cross-linking allows for the preparation of fully recyclable, homogeneous, and conductive nanocomposites. CNT modified with compatible furan groups provided nanocomposites with a relatively large tensile strength and small elongation at break...
January 23, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29360386/lesion-size-does-not-predict-outcomes-in-fresh-osteochondral-allograft-transplantation
#17
Luis E P Tírico, Julie C McCauley, Pamela A Pulido, William D Bugbee
BACKGROUND: Cartilage repair algorithms use lesion size to choose surgical techniques when selecting a cartilage repair procedure. The association of fresh osteochondral allograft (OCA) size with graft survivorship and subjective patient outcomes is still unknown. PURPOSE: To determine if lesion size (absolute or relative) affects outcomes after OCA transplantation. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: The study included 156 knees in 143 patients who underwent OCA transplantation from 1998 to 2014 for isolated femoral condyle lesions...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29357702/the-vascularity-and-osteogenesis-of-a-vascularized-flap-for-the-treatment-of-scaphoid-nonunion-the-pedicle-volar-distal-radial-periosteal-flap
#18
Cary Tanner, Toby Johnson, Alex Majors, Vincent R Hentz, Lisa Husak, Edward Walker Gallego, Brad Christ, Nathan Hoekzema
BACKGROUND: Vascularized periosteal flaps from the distal radius have been previously proposed. The purpose of this study was to investigate the vascularity and osteogenic potential of a vascularized volar distal radial periosteal flap for the treatment of scaphoid nonunion. METHODS: In 5 fresh frozen cadavers, a rectangular periosteal flap was elevated from the distal radius with the pedicle just proximal to the watershed line. Latex dye was injected into the radial artery proximally and the vascularity of the flap characterized by microscopic evaluation...
January 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29352979/evaluation-of-sheep-ovarian-tissue-cryopreserved-by-slow-freezing-or-vitrificaton-after-chick-embryo-chorioallantoic-membrane-transplantation
#19
Mahboubeh Vatanparast, Mohammad Ali Khalili, Nahid Yari, Marjan Omidi, Mehdi Mohsenzadeh
The aim of our investigations was to compare the effectiveness of two methods for cryopreservation of sheep ovarian tissue, slow freezing and vitrification. The quality of cryopreserved tissues was evaluated after 5 days of thawing and chorioallantoic membrane (CAM) transplantation. Follicular structure, stromal integrity and neovascularization were assessed. The areas of fibrosis and necrosis were measured using MICROVISIBLE software, and proliferation was assessed with Ki-67 immunostaning. After 5 days of culture, the proportion of primordial follicles decreased, whereas the primary and intermediary follicles increased insignificantly (p > ...
January 15, 2018: Cryobiology
https://www.readbyqxmd.com/read/29332622/in-vivo-and-in-vitro-strategies-to-support-caprine-preantral-follicle-development-after-ovarian-tissue-vitrification
#20
N J Donfack, K A Alves, B G Alves, R M P Rocha, J B Bruno, L F Lima, C H Lobo, R R Santos, S F S Domingues, M Bertolini, J Smitz, A P R Rodrigues
The aim of the present study was to compare fresh and vitrified goat ovarian tissue after autotransplantation and in vitro culture. Adult goats were completely ovariectomised and each ovarian pair was sliced and distributed among six different treatment groups: fresh control, fresh transplant, fresh culture, vitrified control, vitrified transplant and vitrified culture. Follicular morphology, development, growth, density, revascularisation and hormone production were evaluated in all groups. Three antral follicles (two in the fresh transplant and one in the vitrified transplant groups) were observed on the surface of the graft 90 days after transplantation...
January 15, 2018: Reproduction, Fertility, and Development
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