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https://www.readbyqxmd.com/read/24581253/properties-of-biologic-scaffolds-and-their-response-to-mesenchymal-stem-cells
#1
Knut Beitzel, Mary Beth McCarthy, Mark P Cote, Ryan P Russell, John Apostolakos, Daisy M Ramos, Sangamesh G Kumbar, Andreas B Imhoff, Robert A Arciero, Augustus D Mazzocca
PURPOSE: The purpose of this study was to examine, in vitro, the cellular response of human mesenchymal stem cells (MSCs) to sample types of commercially available scaffolds in comparison with control, native tendon tissue (fresh-frozen rotator cuff tendon allograft). METHODS: MSCs were defined by (1) colony-forming potential; (2) ability to differentiate into tendon, cartilage, bone, and fat tissue; and (3) fluorescence-activated cell sorting analysis (CD73, CD90, CD45)...
March 2014: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/22749483/scapholunate-ligament-reconstruction-using-an-acellular-dermal-matrix-a-mechanical-study
#2
Amirhesam Ehsan, Dong G Lee, Adam J Bakker, Jerry I Huang
PURPOSE: Numerous surgical techniques have been described for the treatment of chronic scapholunate ligament instability. We hypothesized that scapholunate ligament reconstruction using an acellular dermal matrix was biomechanically comparable to previously described surgical reconstructions. METHODS: The scaphoid and lunate with the entire scapholunate ligament were harvested from 15 cadaveric specimens. The scapholunate ligament was transected and reconstructed using an acellular dermal matrix (Arthroflex; LifeNet Health, Virginia Beach, VA) and 4 micro suture anchors in 10 specimens...
August 2012: Journal of Hand Surgery
https://www.readbyqxmd.com/read/22374944/stability-of-double-row-rotator-cuff-repair-is-not-adversely-affected-by-scaffold-interposition-between-tendon-and-bone
#3
COMPARATIVE STUDY
Knut Beitzel, David M Chowaniec, Mary Beth McCarthy, Mark P Cote, Ryan P Russell, Elifho Obopilwe, Andreas B Imhoff, Robert A Arciero, Augustus D Mazzocca
BACKGROUND: Rotator cuff reconstructions may be improved by adding growth factors, cells, or other biologic factors into the repair zone. This usually requires a biological carrier (scaffold) to be integrated into the construct and placed in the area of tendon-to-bone healing. This needs to be done without affecting the constructs mechanics. Hypothesis/ PURPOSE: The hypothesis was that scaffold placement, as an interposition, has no adverse effects on biomechanical properties of double-row rotator cuff repair...
May 2012: American Journal of Sports Medicine
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