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https://www.readbyqxmd.com/read/28642996/central-conduction-abnormalities-in-patients-receiving-levodopa-carbidopa-intestinal-gel-infusion
#1
Francesco Bove, Marco Luigetti, Lara Gallicchio, Valentina Recchia, Antonella Petruzzellis, Riccardo Di Iorio, Filippo Tamma, Alfonso Fasano
In recent years, several studies have reported a relatively high frequency of polyneuropathy in patients with Parkinson's disease (PD), in particular, in patients receiving levodopa-carbidopa intestinal gel (LCIG) infusion. In spite of the several patients investigated with nerve conduction studies, no study has prospectively explored a possible central nervous system involvement of patients receiving LCIG infusion. We prospectively evaluated eight PD patients receiving LCIG infusion, who underwent neurophysiological evaluations with nerve conduction studies, visual, somatosensory and motor evoked potentials before LCIG infusion, and 1 and 6 months after...
June 22, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28638493/tibialis-anterior-muscle-hernia-a-case-of-chronic-dull-pain-and-swelling-in-leg-diagnosed-by-dynamic-ultrasonography
#2
Navneet Sharma, Neeraj Kumar, Richa Verma, Anupam Jhobta
BACKGROUND: Symptomatic muscle hernias are not uncommon in the lower extremities and are a rare cause of chronic leg pain. They are most commonly seen in the tibialis anterior muscle, occurring through fascial defects, usually after trauma. There are about 200 cases of muscle hernias described in the literature. The diagnosis is challenging as most of the patients present with non-specific chronic leg pain. Dynamic muscle ultrasonography at rest and at stress is often used for the diagnosis...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28636429/autograft-versus-allograft-for-posterior-cruciate-ligament-reconstruction-an-updated-systematic-review-and-meta-analysis
#3
John W Belk, Matthew J Kraeutler, Justin M Purcell, Eric C McCarty
BACKGROUND: Multiple studies have demonstrated a higher risk of graft failure after anterior cruciate ligament reconstruction with allograft, but limited data are available comparing outcomes of posterior cruciate ligament reconstruction (PCLR) with autograft versus allograft. PURPOSE: To compare the clinical outcomes of autograft versus allograft for primary PCLR. STUDY DESIGN: Systematic review. METHODS: A systematic review was performed by searching PubMed, the Cochrane Library, and EMBASE to locate studies (level of evidence I-III) comparing clinical outcomes of autograft versus allograft in patients undergoing primary PCLR with the conventional transtibial technique...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28626321/the-effects-of-changes-in-support-and-inclined-boards-on-lower-extremity-muscle-activity
#4
Sangyong Lee, Yoon-Hee Choi, Janggon Kim
[Purpose] The purpose of this study was to identify the effects of changes in support and inclined boards on lower-extremity muscle activity. [Subjects and Methods] The study subjects were 15 healthy adult males. Aero-Step equipment was used as an unstable support, and an inclined board was used to maintain angles of 0° and 20°. Electromyography was employed to analyze lower-extremity muscle activity. [Results] The vastus lateralis, vastus medialis, rectus femoris, gastrocnemius, soleus, and tibialis anterior muscles showed significant differences according to changes in the support and inclined board...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28626313/comparison-of-the-tibialis-anterior-and-soleus-muscles-isolation-ratios-during-the-sit-to-stand-movement-in-elderly-people
#5
Sang-Hoon Lee, Won-Gyu Yoo
[Purpose] To compared activation of the tibialis anterior and soleus muscles during the sit-to-stand movement in elderly people. [Subjects and Methods] Ten elderly women were enrolled. The activities of the dominant lower extremity muscles were measured using a wireless electromyography system. Subjects performed natural sit-to-stand tasks. [Results] In the pre-thigh off phase, the tibialis anterior isolation ratio was significantly higher than the soleus isolation ratio. In the post-thigh off phase, the tibialis and soleus isolation ratios did not significantly differ...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28621464/differences-in-excitability-properties-between-mg-ta-and-apb-motor-axons
#6
Cliff S Klein, Chen Ning Zhao, Hui Liu, Ping Zhou
INTRODUCTION: Excitability properties of motor nerves to different muscles are different, but the explanation is uncertain. We characterized motor axon excitability properties to the medial gastrocnemius (MG) in 27 adults, and made comparisons with the peroneal nerve to the tibialis anterior (TA) and median nerve to the abductor pollicis brevis (APB) in 10 subjects. METHODS: Recordings of multiple excitability properties were made using threshold tracking, stimulating the nerves at the wrist or knee...
June 16, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28620055/the-effects-of-rsr13-on-microvascular-po2-kinetics-and-muscle-contractile-performance-in-the-rat-arterial-ligation-model-of-peripheral-arterial-disease
#7
Aiko Watanabe, David C Poole, Yutaka Kano
Exercise intolerance and claudication are symptomatic of peripheral arterial disease. There is a close relationship between muscle O2 delivery, microvascular oxygen partial pressure (PmvO2) and contractile performance. We therefore hypothesized that a reduction of hemoglobin-oxygen affinity via RSR13 would maintain a higher PmvO2 and enhance blood-muscle O2 transport and contractile function. In male Wistar rats we created hindlimb ischemia via right side iliac artery ligation (AL). The contralateral (left) muscle served as control (CONT)...
June 15, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28619087/longitudinal-estimation-of-intramuscular-tibialis-anterior-coherence-during-subacute-spinal-cord-injury-relationship-with-neurophysiological-functional-and-clinical-outcome-measures
#8
Elisabeth Bravo-Esteban, Julian Taylor, Manuel Aleixandre, Cristina Simón-Martínez, Diego Torricelli, Jose Luis Pons, Gerardo Avila-Martín, Iriana Galán-Arriero, Julio Gómez-Soriano
BACKGROUND: Estimation of surface intramuscular coherence has been used to indirectly assess pyramidal tract activity following spinal cord injury (SCI), especially within the 15-30 Hz bandwidth. However, change in higher frequency (>40 Hz) muscle coherence during SCI has not been characterised. Thus, the objective of this study was to identify change of high and low frequency intramuscular Tibialis Anterior (TA) coherence during incomplete subacute SCI. METHODS: Fifteen healthy subjects and 22 subjects with motor incomplete SCI (American Spinal Injury Association Impairment Scale, AIS, C or D grade) were recruited and tested during 4 sessions performed at 2-week intervals up to 8 months after SCI...
June 15, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28616385/neurophysiological-evidence-of-preserved-connectivity-in-tuber-tissue
#9
H L Kaye, J M Peters, R Gersner, M Chamberland, A Sansevere, A Rotenberg
We present a case of preserved corticospinal connectivity in a cortical tuber, in a 10 year-old boy with intractable epilepsy and tuberous sclerosis complex (TSC). The patient had multiple subcortical tubers, one of which was located in the right central sulcus. In preparation for epilepsy surgery, motor mapping, by neuronavigated transcranial magnetic stimulation (nTMS) coupled with surface electromyography (EMG) was performed to locate the primary motor cortical areas. The resulting functional motor map revealed expected corticospinal connectivity in the left precentral gyrus...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28615977/high-lateral-plantar-pressure-is-related-to-an-increased-tibialis-anterior-fibularis-longus-activity-ratio-in-patients-with-recurrent-lateral-ankle-sprain
#10
Shinshiro Mineta, Takayuki Inami, Raldy Mariano, Norikazu Hirose
INTRODUCTION: Center of pressure (COP) is a sudden displacement at the time of a lateral ankle sprain (LAS). It has been suggested that the distribution of plantar pressure and the quantity of COP displacement are important for assessing the risk of LAS. Therefore, we evaluated the plantar pressure during a single-leg balance test with eyes closed (SLB-C) to identify the factors and characteristics of plantar pressure in people with repeated cases of LAS. METHODS: We recruited 22 collegiate athletes and divided them into an instability group (IG; n=11) and a control group (CG; n=11)...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28615698/divergent-anabolic-signalling-responses-of-murine-soleus-and-tibialis-anterior-muscles-to-chronic-2g-hypergravity
#11
Timur Mirzoev, Sergey Tyganov, Irina Petrova, Vasily Gnyubkin, Norbert Laroche, Laurence Vico, Boris Shenkman
The purpose of the study was to assess the rate of protein synthesis (PS) and elucidate signalling pathways regulating PS in mouse soleus (Sol) and tibialis anterior (TA) muscles following chronic hypergravity (30-day centrifugation at 2G). The content of the key signalling proteins of the various anabolic signalling pathways was determined by Western-blotting. The rate of PS was assessed using in-vivo SUnSET technique. An exposure to 2G centrifugation did not induce any significant changes in the rate of PS as well as phosphorylation status of the key anabolic markers (AKT, p70s6k, 4E-BP1, GSK-3beta, eEF2) in Sol...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28615333/excitability-and-firing-behavior-of-single-slow-motor-axons-transmitting-natural-repetitive-firing-of-human-motoneurons
#12
Lydia P Kudina, Regina E Andreeva
Excitability of motor axons is critically important for realizing their main function - transmitting motoneuron firing to muscle fibres. The present study was designed to explore excitability recovery and firing behavior in single slow axons transmitting human motoneuron firing during voluntary muscle contractions. The abductor digiti minimi, flexor carpi ulnaris, and tibialis anterior were investigated during threshold stimulation of corresponding motor nerves. Motor unit (MU) firing index in response to testing volleys evoking M-responses was used as a physiological measure of axonal excitability and its changes throughout a target interspike interval (ISI) were explored...
June 14, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28611612/spasticity-measurement-based-on-tonic-stretch-reflex-threshold-in-children-with-cerebral-palsy-using-the-pedianklebot
#13
Marco Germanotta, Juri Taborri, Stefano Rossi, Flaminia Frascarelli, Eduardo Palermo, Paolo Cappa, Enrico Castelli, Maurizio Petrarca
Nowadays, objective measures are becoming prominent in spasticity assessment, to overcome limitations of clinical scales. Among others, Tonic Stretch Reflex Threshold (TSRT) showed promising results. Previous studies demonstrated the validity and reliability of TSRT in spasticity assessment at elbow and ankle joints in adults. Purposes of the present study were to assess: (i) the feasibility of measuring TSRT to evaluate spasticity at the ankle joint in children with Cerebral Palsy (CP), and (ii) the correlation between objective measures and clinical scores...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28607086/specific-targeting-of-tgf-%C3%AE-family-ligands-demonstrates-distinct-roles-in-the-regulation-of-muscle-mass-in-health-and-disease
#14
Justin L Chen, Kelly L Walton, Adam Hagg, Timothy D Colgan, Katharine Johnson, Hongwei Qian, Paul Gregorevic, Craig A Harrison
The transforming growth factor-β (TGF-β) network of ligands and intracellular signaling proteins is a subject of intense interest within the field of skeletal muscle biology. To define the relative contribution of endogenous TGF-β proteins to the negative regulation of muscle mass via their activation of the Smad2/3 signaling axis, we used local injection of adeno-associated viral vectors (AAVs) encoding ligand-specific antagonists into the tibialis anterior (TA) muscles of C57BL/6 mice. Eight weeks after AAV injection, inhibition of activin A and activin B signaling produced moderate (∼20%), but significant, increases in TA mass, indicating that endogenous activins repress muscle growth...
June 12, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28606436/a-comparative-outcome-study-of-hamstring-versus-tibialis-anterior-and-synthetic-grafts-for-deltoid-to-triceps-transfers
#15
Jennifer A Dunn, Khalid D Mohammed, Gordon P Beadel, Alastair G Rothwell, Jeremy W Simcock
PURPOSE: To assess elbow extension strength and complications after deltoid-triceps transfers using hamstring tendon graft compared with tibialis anterior and synthetic tendon grafts. METHODS: A retrospective review of deltoid-triceps transfers in patients with tetraplegia performed between 1983 and 2014. RESULTS: Seventy-five people (136 arms) had surgery performed, with the majority undergoing simultaneous bilateral surgery (n = 61; 81%)...
June 9, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28606129/impairment-of-early-fracture-healing-by-skeletal-muscle-trauma-is-restored-by-fk506
#16
Brady J Hurtgen, Beth E P Henderson, Catherine L Ward, Stephen M Goldman, Koyal Garg, Todd O McKinley, Sarah M Greising, Joseph C Wenke, Benjamin T Corona
BACKGROUND: Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration. METHODS: We hypothesized that FK506, an FDA approved immunomodulatory compound with neurotrophic and osteogenic effects, will rescue the early phase of fracture healing which is impaired by concomitant muscle trauma in male (~4 months old) Lewis rats. FK506 (1 mg/kg; i.p.) or saline was administered systemically for 14 days after an endogenously healing tibia osteotomy was created and fixed with an intermedullary pin, and the overlying tibialis anterior (TA) muscle was either left uninjured or incurred volumetric muscle loss injury (6 mm full thickness biopsy from middle third of the muscle)...
June 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28605694/effect-of-increased-kick-frequency-on-propelling-efficiency-and-muscular-co-activation-during-underwater-dolphin-kick
#17
Keisuke Kobayashi Yamakawa, Hirofumi Shimojo, Hideki Takagi, Shozo Tsubakimoto, Yasuo Sengoku
In this study, we investigated the effects of increased kick frequency on the propelling efficiency and the muscular co-activation during underwater dolphin kick. Participants included eight female collegiate swimmers. The participants performed seven 15-m underwater dolphin kick swimming trials at different kick frequencies, which is 85, 90, 95, 100, 105, 110, and 115% of their maximum effort. The Froude (propelling) efficiency of the dolphin kick was calculated from the kinematic analysis. The surface electromyography was measured from six muscles (rectus abdominis, erector spinae, rectus femoris, biceps femoris, tibialis anterior, and gastrocnemius)...
June 9, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28603377/effect-of-prolonged-racing-on-muscle-activity-and-spatiotemporal-variables-double-poling-technique
#18
Kitae Kim, Siddhartha Bikram Panday, In-Sik Shin, Jin-Hae Kim, Hye-Young Kim, Gwang-Jae Yu
[Purpose] The purpose of this study was to examine the effect of a 40-minute race on muscle activity and spatiotemporal cycle variables at four-time points during a 12-km roller skiing test using the double-poling technique. [Subjects and Methods] Five elite cross-country (XC) skiers on the Korean National reserve team participated in the study. Part of a biathlon course that consisted of both flat land and slopes was selected, and three measurements were recorded after every 4-km lap. Spatiotemporal variables, mean frequency and mean amplitude of 6 muscles were the chosen computational parameters...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28603358/analysis-of-the-muscular-activities-of-the-tibialis-anterior-and-gastrocnemius-muscles-in-functional-reach
#19
Se-Won Yoon
[Purpose] This study aimed to examine the changes in the muscle activities of each section of the tibialis anterior and gastrocnemius muscles in the functional reach test. [Subjects and Methods] This study selected those who can walk independently, can reach out their arm up to over 25 cm, can show over 90° shoulder joint bending, have not undergone an operation in the lower limb joint, and are not taking any medication affecting their ability to keep their balance from among 24 elderly males and 24 elderly females...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28601950/increase-in-carbon-dioxide-accelerates-the-performance-of-endurance-exercise-in-rats
#20
Takeshi Ueha, Keisuke Oe, Masahiko Miwa, Takumi Hasegawa, Akihiro Koh, Hanako Nishimoto, Sang Yang Lee, Takahiro Niikura, Masahiro Kurosaka, Ryosuke Kuroda, Yoshitada Sakai
Endurance exercise generates CO2 via aerobic metabolism; however, its role remains unclear. Exogenous CO2 by transcutaneous delivery promotes muscle fibre-type switching to increase endurance power in skeletal muscles. Here we determined the performance of rats running in activity wheels with/without transcutaneous CO2 exposure to clarify its effect on endurance exercise and recovery from muscle fatigue. Rats were randomised to control, training and CO2 groups. Endurance exercise included activity-wheel running with/without transcutaneous CO2 delivery...
June 10, 2017: Journal of Physiological Sciences: JPS
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