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https://www.readbyqxmd.com/read/27926794/metastatic-type-a-thymoma-morphologic-and-genetic-correlation
#1
Tobias Bürger, Inga-Marie Schaefer, Stefan Küffer, Hanibal Bohnenberger, Kirsten Reuter-Jessen, John Kwok-Cheung Chan, Alexander Emmert, Marc Hinterthaner, Alexander Marx, Philipp Ströbel
INTRODUCTION: The vast majority of type A thymomas are diagnosed in tumor stage 1 or 2, and metastatic cases are exceedingly rare. The histological and genetic features of such metastatic type A thymomas have not been described in detail. METHODS: Five metastatic type A thymomas in tumor stage Masaoka IVb that had been reviewed by a panel of expert pathologists were analyzed using comparative genomic hybridization (CGH). All cases had metastasized to the lungs. RESULTS: Cases #1, 2 and 3 showed the prototypic morphology of type A thymomas with mostly solid growth patterns...
December 7, 2016: Histopathology
https://www.readbyqxmd.com/read/27926786/nut-midline-carcinoma-of-the-larynx-an-international-series-and-review-of-the-literature
#2
Henrik Hellquist, Christopher A French, Justin A Bishop, Andrés Coca-Pelaz, Evan J Propst, António Paiva Correia, Bo-Yee Ngan, Ronald Grant, Nicole A Cipriani, David Vokes, Rui Henrique, Fernando Pardal, Jose Ramon Vizcaino, Alessandra Rinaldo, Alfio Ferlito
AIMS: NUT midline carcinoma (NMC) is a rare undifferentiated and aggressive carcinoma that characteristically locates to the midline of the head and neck, and mediastinum. NMC is characterised by chromosomal rearrangements of the gene encoding nuclear protein in testis, NUT, at 15q14. The BRD4 gene on 19q13 is the most common translocation partner forming a fusion oncogene, BRD4-NUT. By the end of 2014, the International NUT Midline Carcinoma Registry had 48 patients treated for NMC. Laryngeal NMC are exceedingly rare and we report a case series of seven cases...
December 7, 2016: Histopathology
https://www.readbyqxmd.com/read/27926380/out-of-hours-workload-management-bayesian-inference-for-decision-support-in-secondary-care
#3
Iker Perez, Michael Brown, James Pinchin, Sarah Martindale, Sarah Sharples, Dominick Shaw, John Blakey
OBJECTIVE: In this paper, we aim to evaluate the use of electronic technologies in out of hours (OoH) task-management for assisting the design of effective support systems in health care; targeting local facilities, wards or specific working groups. In addition, we seek to draw and validate conclusions with relevance to a frequently revised service, subject to increasing pressures. METHODS AND MATERIAL: We have analysed 4 years of digitised demand-data extracted from a recently deployed electronic task-management system, within the Hospital at Night setting in two jointly coordinated hospitals in the United Kingdom...
October 2016: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/27926353/roles-of-body-image-related-experiential-avoidance-and-uncommitted-living-in-the-link-between-body-image-and-women-s-quality-of-life
#4
Inês A Trindade, Cláudia Ferreira, José Pinto-Gouveia
The current study aimed to test whether the associations of body mass index, body image discrepancy, and social comparison based on physical appearance with women's psychological quality of life (QoL) would be explained by the mechanisms of body image-related experiential avoidance and patterns of uncommitted living. The sample was collected from October 2014 to March 2015 and included 737 female college students (aged between 18 and 25 years) who completed validated self-report measures. Results demonstrated that the final path model explained 43% of psychological QoL and revealed an excellent fit...
December 7, 2016: Women & Health
https://www.readbyqxmd.com/read/27925613/experience-dependent-hippocampal-pattern-differentiation-prevents-interference-during-subsequent-learning
#5
Serra E Favila, Avi J H Chanales, Brice A Kuhl
The hippocampus is believed to reduce memory interference by disambiguating neural representations of similar events. However, there is limited empirical evidence linking representational overlap in the hippocampus to memory interference. Likewise, it is not fully understood how learning influences overlap among hippocampal representations. Using pattern-based fMRI analyses, we tested for a bidirectional relationship between memory overlap in the human hippocampus and learning. First, we show that learning drives hippocampal representations of similar events apart from one another...
April 6, 2016: Nature Communications
https://www.readbyqxmd.com/read/27925549/pre-teen-behaviour-issues-less-likely-if-dad-adjusts-to-parenthood
#6
(no author information available yet)
Children whose fathers adjust well to parenthood and feel confident in their new role are less likely to have behavioural problems in their pre-teen years, new study results suggest.
December 7, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27925479/psychological-adjustment-to-craniofacial-conditions-excluding-oral-clefts-a-review-of-the-literature
#7
Kristin Billaud Feragen, Nicola Marie Stock
OBJECTIVE: A congenital craniofacial anomaly (CFA) is expected to impact upon several domains of psychological, emotional and social functioning, yet no recent reviews have comprehensively summarised the available literature. Further, existing reviews tend to draw upon literature in the field of cleft lip and palate, and do not give substantive attention to other types of CFAs. DESIGN: A review of 41 papers published between January 2000 and March 2016 pertaining to psychological adjustment to CFAs...
December 7, 2016: Psychology & Health
https://www.readbyqxmd.com/read/27925449/confirmatory-factor-analysis-of-a-questionnaire-measure-of-managerial-stigma-towards-employee-depression
#8
Angela J Martin, Rebecca Giallo
Managers' attitudes play a key role in how organizations respond to employees with depression. We examine the measurement properties of a questionnaire designed to assess managerial stigma towards employees with depression. Using data from a sample of 469 Australian managers representing a wide range of industries and work settings, we conducted a confirmatory factor analysis to assess three proposed subscales representing affective, cognitive and behavioural forms of stigma. Results were equivocal indicating acceptable fit for two-factor (affective and cognitive + behavioural), three-factor (affective, cognitive and behavioural) and higher order models...
December 2016: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/27925435/predicting-the-intention-to-use-condoms-and-actual-condom-use-behaviour-a-three-wave-longitudinal-study-in-ghana
#9
Enoch Teye-Kwadjo, Ashraf Kagee, Hermann Swart
BACKGROUND: Growing cross-sectional research shows that the theory of planned behaviour (TPB) is robust in predicting intentions to use condoms and condom use behaviour. Yet, little is known about the TPB's utility in explaining intentions to use condoms and condom use behaviour over time. METHODS: This study used a longitudinal design and latent variable structural equation modelling to test the longitudinal relationships postulated by the TPB. School-going youths in Ghana provided data on attitudes, subjective norms, perceived control, intentions, and behaviour regarding condom use at three time points, spaced approximately three months apart...
December 7, 2016: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/27925432/ceos-theory-a-comprehensive-approach-to-understanding-hard-to-maintain-behaviour-change
#10
Ron Borland
This paper provides a brief introduction to CEOS theory, a comprehensive theory for understanding hard to maintain behaviour change. The name CEOS is an acronym for Context, Executive, and Operational Systems theory. Behaviour is theorised to be the result of the moment by moment interaction between internal needs (operational processes) in relation to environmental conditions, and for humans this is augmented by goal-directed, executive action which can transcend immediate contingencies. All behaviour is generated by operational processes...
December 7, 2016: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/27925428/measuring-sedentary-behaviours-in-patients-with-idiopathic-pulmonary-fibrosis-using-wrist-worn-accelerometers
#11
Chris Atkins, Mark Baxter, Andrew Jones, Andrew Wilson
Introduction - Idiopathic pulmonary fibrosis (IPF) patients suffer increasing functional limitation with disease worsening disease. Increasing time in sedentary behaviour has been associated with poorer quality of life. Determining thresholds for activity in patients with respiratory disease is difficult due to variable cardiorespiratory limitations between individuals. Measuring sedentary behaviour is not confounded by this limitation and may be a better measurement of activity in patients with respiratory disease...
December 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27925361/implicit-alcohol-attitudes-predict-drinking-behaviour-over-and-above-intentions-and-willingness-in-young-adults-but-willingness-is-more-important-in-adolescents-implications-for-the-prototype-willingness-model
#12
Emma L Davies, Aspasia E Paltoglou, David R Foxcroft
OBJECTIVES: Dual process models, such as the Prototype Willingness Model (PWM), propose to account for both intentional and reactive drinking behaviour. Current methods of measuring constructs in the PWM rely on self-report, thus require a level of conscious deliberation. Implicit measures of attitudes may overcome this limitation and contribute to our understanding of how prototypes and willingness influence alcohol consumption in young people. This study aimed to explore whether implicit alcohol attitudes were related to PWM constructs and whether they would add to the prediction of risky drinking...
December 7, 2016: British Journal of Health Psychology
https://www.readbyqxmd.com/read/27925354/detecting-mental-health-problems-and-suicidal-motives-among-terrorists-and-mass-shooters
#13
Adam Lankford
BACKGROUND: For years, many scholars dismissed the possibility that terrorists - including suicide attackers - could be mentally ill or primarily suicidal. However, that view is gradually changing. AIM: Researchers continue to face significant challenges when attempting to detect mental health problems and suicidal motives among terrorists and mass shooters, because many offenders cannot easily be psychologically assessed. This article offers several specific recommendations for how researchers can better understand offenders' mental state by studying their life histories and behaviour...
December 2016: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/27925295/parents-perceptions-are-that-their-child-s-health-related-quality-of-life-is-more-impaired-when-they-have-a-wheat-rather-than-a-grass-allergy
#14
Nora Borres, Nora Nilsson, Isabel Drake, Sigrid Sjölander, Caroline Nilsson, Gunilla Hedlin, Björn Nordlund
AIM: It is unknown whether food allergies have greater impact on quality of life than respiratory allergies. This study compared health-related quality of life (HRQoL) in children allergic to wheat or grass. METHODS: We surveyed 63 children with wheat allergies (median age of five) and 72 with grass allergies (median age 12), with their parents. The Child Health Questionnaires for parents (CHQ-PF28) and children (CHQ-CF87) were applied. RESULTS: The parents of children in the wheat group recorded significantly lower CHQ-PF28 scores for the impact of their child's allergy on general behaviour, general health perceptions, parental impact of emotions and time and family activities, than the parents of children with grass allergies (p values <0...
December 7, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27925292/cognitive-impairment-in-parkinson-s-disease-impact-on-quality-of-life-of-carers
#15
R A Lawson, A J Yarnall, F Johnston, G W Duncan, T K Khoo, D Collerton, J P Taylor, D J Burn
BACKGROUND: The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition to the management of motor symptoms, carers of PwP and cognitive impairment may experience increased levels of burden and poorer QoL compared with carers of PwP without cognitive impairment. This study aimed to investigate the impact of cognitive impairment in PD upon QoL of carers...
December 7, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27925149/behavioural-interventions-to-promote-workers-use-of-respiratory-protective-equipment
#16
REVIEW
Bao Yen Luong Thanh, Malinee Laopaiboon, David Koh, Pornpun Sakunkoo, Hla Moe
BACKGROUND: Respiratory hazards are common in the workplace. Depending on the hazard and exposure, the health consequences may include: mild to life-threatening illnesses from infectious agents, acute effects ranging from respiratory irritation to chronic lung conditions, or even cancer from exposure to chemicals or toxins. Use of respiratory protective equipment (RPE) is an important preventive measure in many occupational settings. RPE only offers protection when worn properly, when removed safely and when it is either replaced or maintained regularly...
December 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27925139/association-of-grip-strength-upper-arm-circumference-and-waist-circumference-with-dementia-in-older-adults-of-the-wise-study-a-cross-sectional-analysis
#17
H L Ong, S H S Chang, E Abdin, J A Vaingankar, A Jeyagurunathan, S Shafie, H Magadi, S A Chong, M Subramaniam
OBJECTIVE: We examined the associations of handgrip strength, upper arm circumference, and waist circumference with dementia among Singapore older adults. DESIGN: Cross-sectional epidemiological study. SETTING: Residential homes, day care centres, nursing homes and institutions. PARTICIPANTS: 2,565 men and women aged 60 years and above who participated in the Well-being of the Singapore Elderly (WiSE) study in 2013. MEASUREMENTS: Socio-demographic correlates, dietary habits, health behaviours, grip strength, upper arm circumference, and waist circumference were collected...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925019/entering-and-exiting-behaviour-of-the-phlebotomine-sand-fly-lutzomyia-longiflocosa-diptera-psychodidae-in-rural-houses-of-the-sub-andean-region-of-colombia
#18
Raúl Hernando Pardo, Erika Santamaría, Olga Lucia Cabrera
The present study identified the entering and exiting sites for Lutzomyia longiflocosa in rural houses of the sub-Andean region in Colombia. Entering sites were identified with sticky traps set up outside the bedrooms, around the eave openings, and with cage traps enclosing the slits in the doors and windows inside the bedrooms. Exiting sites were identified by releasing groups of females indoors. These females were blood fed and marked with fluorescent powders. Females were recaptured with the trap placement described above but set up on the opposite sides of the openings...
December 1, 2016: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/27924962/attenuation-of-unpredictable-chronic-mild-stress-induced-deficits-in-rats-by-apomorphine
#19
Muhammad Farhan, Darakshan Jabeen Haleem
OBJECTIVE: To investigate the effects of repeated doses of apomorphine in rats exposed to unpredictable chronic mild stress. METHODS: The experimental case-control study was conducted in March 2011 at the Department of Biochemistry, University of Karachi, and comprised albino-wistar rats. The experimental animals were exposed to a schedule of unpredictable chronic mild stress, while control animals were left in the cages. Animals of stressed and unstressed group were administrated with apomorphine at dose of 1...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27924960/sun-exposure-behaviours-attitudes-and-protection-practices-among-prince-sattam-bin-abdulaziz-university-students-a-survey-study
#20
Nasr Addin Othman Bahakim, Bader Ghanem Alanazi, Mohammed Yousef Alead, Abdulrahman Bader Alaql, Nasser Abdulla Al-Ogail, Fahad Abdullah Alghulaydhawi
OBJECTIVE: To evaluate sun exposure behaviours, sun protection practices, general knowledge, attitudes and awareness of University students about the benefits of sun exposure and harmful effects of too much or avoidance of sun exposure. METHODS: This cross-sectional survey study was conducted in December 2014 and January2015 at Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia. A questionnaire consisting of multiple-choice closed questions was used...
December 2016: JPMA. the Journal of the Pakistan Medical Association
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