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https://www.readbyqxmd.com/read/28098920/-too-long-in-tbs-a-study-on-patients-receiving-forensic-psychiatric-tbs-treatment-for-15-years-or-longer
#1
H Nijman, S Lammers, M Vrinten, E Bulten
In 2013 in the Netherlands about 100 forensic psychiatric patients were treated in tbs-hospitals for 15 years or more.<br/> AIM: To investigate the variables that characterise patients who have been receiving forensic psychiatric treatment (tbs) for 15 years or more, and to obtain insight in which actions might be helpful to facilitate discharge or transfer of such patients to other (mental health care) facilities, according to their caregivers and experts.<br/> METHOD: The group of long-term tbs-patients (n = 97) was compared with regard to diagnostic characteristics, 'basic historical risks' (as assessed by risk assessment instruments), and behaviour  to three other groups of forensic patients: a...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28098771/breast-cancer-brain-metastases-clonal-evolution-in-clinical-context
#2
REVIEW
Jodi M Saunus, Amy E McCart Reed, Zhun Leong Lim, Sunil R Lakhani
Brain metastases are highly-evolved manifestations of breast cancer arising in a unique microenvironment, giving them exceptional adaptability in the face of new extrinsic pressures. The incidence is rising in line with population ageing, and use of newer therapies that stabilise metastatic disease burden with variable efficacy throughout the body. Historically, there has been a widely-held view that brain metastases do not respond to circulating therapeutics because the blood-brain-barrier (BBB) restricts their uptake...
January 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28098741/does-familial-aggregation-of-chronic-low-back-pain-impact-on-recovery-a-population-based-twin-study
#3
J R Zadro, D Shirley, J F Sanchez-Romera, J R Ordoñana, P H Ferreira
STUDY DESIGN: Longitudinal twin-cohort study. OBJECTIVE: To investigate the impact familial aggregation of chronic low back pain (LBP) has on the recovery from chronic LBP. SUMMARY OF BACKGROUND DATA: LBP is a worldwide problem, with pain and disability often becoming chronic. Genetics and familial behaviours could significantly impact the recovery from chronic LBP but have not been extensively investigated. METHODS: 624 Spanish twins from the Murcia Twin Registry reported experiencing chronic LBP within the past two years during the 2009/11 data collection wave and were followed up in 2013...
January 16, 2017: Spine
https://www.readbyqxmd.com/read/28098502/united-kingdom-national-paediatric-bilateral-project-results-of-professional-rating-scales-and-parent-questionnaires
#4
H E Cullington, D Bele, J C Brinton, S Cooper, M Daft, J Harding, N Hatton, J Humphries, M E Lutman, J Maddocks, J Maggs, K Millward, G O'Donoghue, S Patel, K Rajput, V Salmon, T Sear, A Speers, A Wheeler, K Wilson
OBJECTIVES: This fourteen-centre project used professional rating scales and parent questionnaires to assess longitudinal outcomes in a large non-selected population of children receiving simultaneous and sequential bilateral cochlear implants. METHODS: This was an observational non-randomized service evaluation. Data were collected at four time points: before bilateral cochlear implants or before the sequential implant, one year, two years, and three years after...
January 18, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28098344/inhibition-of-oxytocin-and-vasopressin-neuron-activity-in-rat-hypothalamic-paraventricular-nucleus-by-relaxin-3-rxfp3-signalling
#5
Alan Kania, Anna Czerw, Agnieszka Grabowiecka, Camila de Ávila, Tomasz Blasiak, Zenon Rajfur, Marian H Lewandowski, Grzegorz Hess, Elena Timofeeva, Andrew L Gundlach, Anna Blasiak
KEY-POINTS: Relaxin-3 is a stress-responsive neuropeptide that acts at its cognate receptor, RXFP3, to alter behaviours including feeding. In this study, we have demonstrated a direct, RXFP3-dependent, inhibitory action of relaxin-3 on oxytocin and vasopressin PVN neuron electrical activity, a putative cellular mechanism of orexinergic actions of relaxin-3. We observed a Gαi/o -protein-dependent inhibitory influence of selective RXFP3 activation on PVN neuronal activity in vitro and demonstrated a direct action of RXFP3 activation on oxytocin and vasopressin PVN neurons, confirmed by their abundant expression of RXFP3 mRNA...
January 18, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28098324/ionic-screening-and-dissociation-are-crucial-for-understanding-chemical-self-propulsion-in-polar-solvents
#6
Aidan T Brown, Wilson C K Poon, Christian Holm, Joost de Graaf
Polar solvents like water support the bulk dissociation of themselves and their solutes into ions, and the re-association of these ions into neutral molecules in a dynamic equilibrium, e.g., H2O2 ⇌ H(+) + HO2(-). Using continuum theory, we study the influence of these association-dissociation reactions on the self-propulsion of colloids driven by surface chemical reactions (chemical swimmers). We find that association-dissociation reactions should have a strong influence on swimmers' behaviour, and therefore should be included in future modelling...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28098315/a-ph-responsive-wormlike-micellar-system-of-a-noncovalent-interaction-based-surfactant-with-a-tunable-molecular-structure
#7
Wanli Kang, Pengxiang Wang, Haiming Fan, Hongbin Yang, Caili Dai, Xia Yin, Yilu Zhao, Shujun Guo
Responsive wormlike micelles are very useful in a number of applications, whereas it is still challenging to create dramatic viscosity changes in wormlike micellar systems. Here we developed a pH-responsive wormlike micellar system based on a noncovalent constructed surfactant, which is formed by the complexation of N-erucamidopropyl-N,N-dimethylamine (UC22AMPM) and citric acid at the molar ratio of 3 : 1 (EACA). The phase behavior, aggregate microstructure and viscoelasticity of EACA solutions were investigated by macroscopic appearance observation, rheological and cryo-TEM measurements...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28098305/phase-behaviour-and-temperature-responsive-properties-of-a-gemini-surfactant-brij-30-water-system
#8
Chuanhong Han, Yan Guo, Xiaoxiao Chen, Meihuan Yao, Yingtian Zhang, Qirui Zhang, Xilian Wei
The phase behaviour of a ternary system composed of cationic gemini surfactant 2-hydroxypropyl-1,3-bis(myristyldimethylammonium chloride) (14-3(OH)-14(2Cl)), nonionic surfactant polyoxyethylene laurel ether (C12H25(OCH2CH2)10OH, Brij-30) and H2O was studied and its phase diagram was determined. In several different phase regions identified in the phase diagram, the viscoelastic worm-like micellar solution region was investigated. The focus of the investigation was the increase in the viscosity of the micellar solution with the temperature and the Brij-30 content, as suggested by a partial region of the triangular phase diagram...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28098234/maternal-cortisol-stimulates-neurogenesis-and-affects-larval-behaviour-in-zebrafish
#9
Carol Best, Deborah M Kurrasch, Mathilakath M Vijayan
Excess glucocorticoid transferred from stressed mother to the embryo affects developing vertebrate offspring, but the underlying programming events are unclear. In this study, we tested the hypothesis that increased zygotic glucocorticoid deposition, mimicking a maternal stress scenario, modifies early brain development and larval behaviour in zebrafish (Danio rerio). Cortisol was microinjected into the yolk at one cell-stage, to mimic maternal transfer, and the larvae [96 hours post-fertilization (hpf)] displayed increased activity in light and a reduction in thigmotaxis, a behavioural model for anxiety, suggesting an increased propensity for boldness...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28098153/mecp2-regulates-cortical-plasticity-underlying-a-learned-behaviour-in-adult-female-mice
#10
Keerthi Krishnan, Billy Y B Lau, Gabrielle Ewall, Z Josh Huang, Stephen D Shea
Neurodevelopmental disorders are marked by inappropriate synaptic connectivity early in life, but how disruption of experience-dependent plasticity contributes to cognitive and behavioural decline in adulthood is unclear. Here we show that pup gathering behaviour and associated auditory cortical plasticity are impaired in female Mecp2(het) mice, a model of Rett syndrome. In response to learned maternal experience, Mecp2(het) females exhibited transient changes to cortical inhibitory networks typically associated with limited plasticity...
January 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28098147/nanoparticle-induced-unusual-melting-and-solidification-behaviours-of-metals
#11
Chao Ma, Lianyi Chen, Chezheng Cao, Xiaochun Li
Effective control of melting and solidification behaviours of materials is significant for numerous applications. It has been a long-standing challenge to increase the melted zone (MZ) depth while shrinking the heat-affected zone (HAZ) size during local melting and solidification of materials. In this paper, nanoparticle-induced unusual melting and solidification behaviours of metals are reported that effectively solve this long-time dilemma. By introduction of Al2O3 nanoparticles, the MZ depth of Ni is increased by 68%, while the corresponding HAZ size is decreased by 67% in laser melting at a pulse energy of 0...
January 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28098145/highly-thermal-stable-ferromagnetism-by-a-natural-composite
#12
Tianyu Ma, Junming Gou, Shanshan Hu, Xiaolian Liu, Chen Wu, Shuai Ren, Hui Zhao, Andong Xiao, Chengbao Jiang, Xiaobing Ren, Mi Yan
All ferromagnetic materials show deterioration of magnetism-related properties such as magnetization and magnetostriction with increasing temperature, as the result of gradual loss of magnetic order with approaching Curie temperature TC. However, technologically, it is highly desired to find a magnetic material that can resist such magnetism deterioration and maintain stable magnetism up to its TC, but this seems against the conventional wisdom about ferromagnetism. Here we show that a Fe-Ga alloy exhibits highly thermal-stable magnetization up to the vicinity of its TC, 880 K...
January 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28098078/knowledge-attitude-and-behaviour-of-the-general-population-towards-organ-donation-an-indian-perspective
#13
Poreddi Vijayalakshmi, T S Sunitha, Sailaxmi Gandhi, Rohini Thimmaiah, Suresh Bada Math
BACKGROUND: The rate of organ donation in India is low and research on organ donation among the general population is limited. We assessed the knowledge, attitude and willingness to donate organs among the general population. METHODS: We carried out a cross-sectional descriptive study among 193 randomly selected relatives of patients (not of those seeking organ donation) attending the outpatient department at a tertiary care centre. We used a structured questionnaire to collect data through face-to-face interviews...
September 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/28098076/melting-of-large-pt-mgo-100-icosahedra
#14
Kevin Rossi, Tom Ellaby, Lauro Oliver Paz Borbon, Ivailo Atanasov, Luca Pavan, Francesca Baletto
On the basis of ab-initio calculations, we present a new parametrisation of the Vervisch-Mottet-Goniakowski (VMG) potential [Vervisch et al. Phys. Rev B24, 245411 (2002)] for modelling the oxide-metal interaction. Applying this model to mimic the finite temperature behaviour of large platinum icosahedra deposited on the pristine MgO(100), we find the nanoparticle undergoes two solid-solid transitions. At 650 K the ���squarisation��� of the interface layer, while a full reshaping towards a fcc architecture takes place above 950 K...
January 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28098073/classical-density-functional-study-of-wetting-transitions-on-nanopatterned-surfaces
#15
P Yatsyshin, A O Parry, C Rascón, S Kalliadasis
Even simple fluids on simple substrates can exhibit very rich surface phase behaviour. To illustrate this, we consider fluid adsorption on a planar wall chemically patterned with a deep stripe of a different material. In this system, two phase transitions compete: unbending and pre-wetting. Using microscopic density-functional theory, we show that, for thin stripes, the lines of these two phase transitions may merge, leading to a new two-dimensional-like wetting transition occurring along the walls. The influence of intermolecular forces and interfacial fluctuations on this phase transition and at complete pre-wetting are considered in detail...
January 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28098051/chronic-fatigue-syndrome-cognitive-behavioural-and-emotional-processing-vulnerability-factors
#16
Samantha K Brooks, Trudie Chalder, Katharine A Rimes
BACKGROUND: Cognitive-behavioural models of chronic fatigue syndrome (CFS) suggest that personality factors such as perfectionism and high moral standards may contribute to the development of CFS. AIMS: To investigate cognitive, behavioural and emotional processing risk factors for CFS. METHOD: CFS patients (n = 67) at a UK specialist clinic completed questionnaires about psychological characteristics both currently and retrospectively (6 months pre-CFS onset)...
January 18, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28098023/key-parameters-for-behaviour-related-to-source-separation-of-household-organic-waste-a-case-study-in-hanoi-vietnam
#17
Kosuke Kawai, Luong Thi Mai Huong
Proper management of food waste, a major component of municipal solid waste (MSW), is needed, especially in developing Asian countries where most MSW is disposed of in landfill sites without any pretreatment. Source separation can contribute to solving problems derived from the disposal of food waste. An organic waste source separation and collection programme has been operated in model areas in Hanoi, Vietnam, since 2007. This study proposed three key parameters (participation rate, proper separation rate and proper discharge rate) for behaviour related to source separation of household organic waste, and monitored the progress of the programme based on the physical composition of household waste sampled from 558 households in model programme areas of Hanoi...
January 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28098021/don-t-accept-bullying-especially-due-to-race
#18
Zeba Arif
A recent study from Birmingham City University uncovered some alarming examples of students' reactions to negative feedback from their mentors, ranging from manipulative behaviour to making threats and allegations of bullying.
January 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28097738/enhanced-predictive-signalling-in-schizophrenia
#19
Katharina Schmack, Marcus Rothkirch, Josef Priller, Philipp Sterzer
Positive symptoms of schizophrenia such as delusions and hallucinations are thought to arise from an alteration in predictive mechanisms of the brain. Here, we empirically tested the hypothesis that schizophrenia is associated with an enhanced signalling of higher-level predictions that shape perception into conformity with acquired beliefs. Twenty-one patients with schizophrenia and twenty-eight healthy controls matched for age and gender took part in a functional magnetic resonance imaging (fMRI) experiment that assessed the effect of an experimental manipulation of cognitive beliefs on the perception of an ambiguous visual motion stimulus...
January 18, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28097716/parental-knowledge-of-antibiotic-use-in-children-with-respiratory-infections-a-systematic-review
#20
REVIEW
Lourdes Cantarero-Arévalo, Mia Pavelics Hallas, Susanne Kaae
OBJECTIVE: Antimicrobial resistance (AMR) is an increasing global problem. AMR threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. The misuse and overuse of antibiotics (AB) is the major contributor to the emergence of resistant bacteria in humans. To present and describe characteristics in parents' knowledge about when and how to use AB for an upper respiratory tract infection (URTI), their attitudes towards doctors and AB use in general, and their behaviour when their child suffers from an URTI...
February 2017: International Journal of Pharmacy Practice
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