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Adhesive capsulitis

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https://www.readbyqxmd.com/read/29777589/low-adhesive-ethylene-vinyl-alcohol-based-packaging-to-xenogeneic-islets-encapsulation-for-type-1-diabetes-treatment
#1
Kai-Chiang Yang, Goichi Yanai, Sin-Yu Yang, Priyadarshini Canning, Yoshio Satou, Masako Kawagoe, Shoichiro Sumi
Transplantation of encapsulated porcine islets is proposed to treat type 1 diabetes. However, envelopment of fibrous tissue and infiltration of immune cells impair islets function and eventually cause implant failure. It is known that hemodialysis using an ethylene vinyl alcohol (EVOH) membrane results in minor tissue responses. Therefore, we hypothesized that using a low adhesive EVOH membrane for encapsulation may prevent host cell accumulation and fibrous capsule formation. In this study, rat islets suspended in chitosan gel were encapsulated in bags made from highly porous EVOH membranes, and their in vitro insulin secretion function as well as in vivo performance were evaluated...
May 19, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29768929/current-concepts-in-revision-hip-arthroscopy
#2
Renato Locks, Ioanna Bolia, Hajime Utsunomiya, Karen Briggs, Marc J Philippon
Hip arthroscopy is an evolving procedure and its indications have expanded. The number of patients undergoing this procedure has increased significantly as well as the number of surgeons being trained. This has resulted in a notable increase in post-operative complication rates creating the need to develop advanced hip arthroscopic techniques. Revision hip arthroscopy is often complex and many factors should be considered to achieve a satisfactory clinical outcome. Careful pre-operative planning and agreement of expectations between the physician and patient regarding the procedure are important...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29764307/effectiveness-of-hydrodilatation-in-adhesive-capsulitis-of-shoulder-a-systematic-review-and-meta-analysis
#3
M Saltychev, K Laimi, P Virolainen, M Fredericson
BACKGROUND AND AIMS: Even though hydrodilatation has been used for 50 years, the evidence on its effectiveness is not clear. Only one earlier review has strictly focused on this treatment method. The aims of this study are to evaluate the evidence on the effectiveness of hydrodilatation in treatment of adhesive capsulitis and, if appropriate, to assess the correlation between the effects of this procedure and the amount of fluid injected. MATERIALS AND METHODS: A literature search on MEDLINE, Embase, Scopus, Cochrane Central, Web of Science, and CINAHL databases was done; random-effects meta-analysis and meta-regression were employed; and cost-effectiveness and safeness analyses were left outside the scope of the review...
May 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29753567/junctional-adhesion-molecules-jam-b-and-jam-c-promote-autoimmune-mediated-liver-fibrosis-in-mice
#4
Edith Hintermann, Monika Bayer, Clara Benedetta Conti, Sina Fuchs, Michel Fausther, Patrick S Leung, Michel Aurrand-Lions, Richard Taubert, Josef M Pfeilschifter, Mireen Friedrich-Rust, Detlef Schuppan, Jonathan A Dranoff, M Eric Gershwin, Michael P Manns, Beat A Imhof, Urs Christen
Fibrosis remains a serious health concern in patients with chronic liver disease. We recently reported that chemically induced chronic murine liver injury triggers increased expression of junctional adhesion molecules (JAMs) JAM-B and JAM-C by endothelial cells and de novo synthesis of JAM-C by hepatic stellate cells (HSCs). Here, we demonstrate that biopsies of patients suffering from primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) or autoimmune hepatitis (AIH) display elevated levels of JAM-C on portal fibroblasts (PFs), HSCs, endothelial cells and cholangiocytes, whereas smooth muscle cells expressed JAM-C constitutively...
May 9, 2018: Journal of Autoimmunity
https://www.readbyqxmd.com/read/29738376/naoxintong-capsule-inhibits-carrageenan-induced-thrombosis-in-mice
#5
Qi Li, Yi Chen, Dan Zhao, Zhuo Wei, Shuang Zhang, Yuanli Chen, Yong Wang, Ke Qian, Buchang Zhao, Yan Zhu, Xiumei Gao, Pengzhi Dong, Xiaoju Li, Yajun Duan, Jihong Han, Xiaoxiao Yang
Formation of thrombosis is mainly associated with dysfunctions of endothelial cells. NaoXinTong capsule (NXT), a traditional Chinese medicine, has been demonstrated multiple protective effects on vascular systems. However, it is unknown the effect of NXT on thrombosis. In this study, we determined if NXT can inhibit carrageenan-induced thrombosis and the underlying mechanisms. Two days after carrageenan injection, severe thrombi were found in blood vessels of mouse tail and liver. In contrast, thrombi were substantially reduced by NXT treatment, and the reduction was associated with reduced serum tumor necrosis factor α and P-selectin levels...
April 24, 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29699862/effect-of-nonoperative-concomitant-intraarticular-pathologies-on-the-outcome-of-arthroscopic-capsular-release-for-adhesive-capsulitis-of-the-shoulder
#6
Fatih Yildiz, Abdulkadir Sari, Anil Pulatkan, Vahdet Ucan, Alauddin Kochai, Kerem Bilsel
OBJECTIVE: The aim of this study was to investigate whether coexistent intraarticular lesions are negative prognostic factors for the results of arthroscopic capsular release in frozen shoulder patients. METHODS: Seventy-two patients who met inclusion criteria and underwent arthroscopic capsular release between March 2011 and August 2015 for the frozen shoulder were retrospectively evaluated. The patients were divided into two groups according to existence of concomitant intraarticular pathologies detected during arthroscopy...
April 23, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29698293/can-shoulder-muscle-activity-be-evaluated-with-ultrasound-shear-wave-elastography
#7
Kwanwoo Kim, Hyun-Jung Hwang, Seul-Gi Kim, Jin-Hyuck Lee, Woong Kyo Jeong
BACKGROUND: Quantitative assessment of rotator cuff muscle activity is important in the treatment of shoulder disorders. However, the known methods for assessing rotator cuff muscle activity thus far have been inaccurate, invasive, and inconvenient. QUESTIONS/PURPOSES: (1) Does the activity of the deltoid, supraspinatus, and infraspinatus muscles measured using ultrasound shear wave elastography have a linear correlation with muscle activity assessed using generally used methods, including isokinetic dynamometry and electromyography? (2) Does the activity of the deltoid, supraspinatus, and infraspinatus muscles measured using shear wave elastography show good intraobserver and interobserver reliability? METHODS: Twelve volunteers participated in intrasession reliability experiments...
April 24, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29689370/dissolution-of-fine-particle-fraction-from-truncated-anderson-cascade-impactor-with-an-enhancer-cell
#8
Justin Yong Soon Tay, Celine Valeria Liew, Paul Wan Sia Heng
Dissolution testing for inhalers were previously conducted either on unfractionated drug-carrier powders or drug of specific aerodynamic particle size. In this study, the collection of the full fine particle fraction (FPF) was attempted on a single stage. Capsules containing 30 mg of 2% salbutamol sulfate (SS) was tested to have a FPF of 9 ± 1% using the full set of Andersen cascade impactor (ACI) and a modified Rotahaler® capable of achieving 4.0 kPa pressure drop at 60 L/min air flow rate. A truncated ACI comprising the USP throat, pre-separator, stage 0, stage 4, stage F, polytetrafluoroethylene funnel (TF) and small collection plate (sCP) was found to be capable of achieving a FPF of 9% collected on TF and sCP...
April 21, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29676135/-protective-effect-of-longxue-tongluo-capsule-on-oxidized-low-density-lipoprotein-damage-to-human-umbilical-vein-endothelial-cells
#9
Hong-Mei Wang, Jian-Ming Zhou, Yao-Zhong Lv, Jun Zhou, Zhen-Zhong Wang, Wen-Zhe Huang, Peng-Fei Tu, Wei Xiao
To observe the protective effect of Longxue Tongluo capsule (LTC) on human umbilical vein endothelial cells (EAhy.926 cells) injury induced by oxidized low-density lipoprotein (ox-LDL, 100 mg·L⁻¹). The effect of the cell viability of LTCin alleviating OX-LDL-induced endothelial cell injury was determined by MTT and LDH assay. The effect of LTC on lactic dehydrogenase (LDH), nitric oxide (NO), super oxide dlsmutase (SOD) and malondialdehyde (MDA) levels were detected by corresponding assay kits according to manufacturer's instruction...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29658838/effectiveness-of-translational-manipulation-under-interscalene-block-for-the-treatment-of-adhesive-capsulitis-of-the-shoulder-a-nonrandomized-clinical-trial
#10
Daniel G Rendeiro, Gail D Deyle, Norman W Gill, Guy R Majkowski, Ian E Lee, Dale A Jensen, Robert S Wainner
STUDY DESIGN: Nonrandomized controlled trial. OBJECTIVE: To determine whether translational manipulation under anesthesia/local block (TMUA) adds to the benefit of mobilization and range of motion exercise for improving pain and functional status among patients with adhesive capsulitis of the shoulder (AC). BACKGROUND: TMUA has been shown to improve pain and dysfunction in patients with AC. This intervention has not been directly compared to physical therapy treatment without TMUA in a prospective trial...
April 16, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29653215/the-effect-of-mesoporous-silica-impregnation-on-tribo-electrification-characteristics-of-flurbiprofen
#11
Mohammad S Afzal, Faiza Zanin, Muhammad Usman Ghori, Marta Granollers, Enes Šupuk
Tribo-electrification is a common occurrence within the pharmaceutical industry where solid dosage forms constitute majority of pharmaceutical formulations. Tribo-electrification of powders leads to a range of complications such as adhesion of particulate material to the processing equipment resulting in segregation, affecting the content uniformity. Flurbiprofen, a highly charging material, was used as a model drug to investigate the tribo-electrification and adhesion characteristics by impregnating the model drug inside a mesoporous silica matrix...
April 10, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29629805/comparison-between-image-guided-and-landmark-based-glenohumeral-joint-injections-for-the-treatment-of-adhesive-capsulitis-a-cost-effectiveness-study
#12
Soterios Gyftopoulos, Valentino Abballe, Mandeep S Virk, James Koo, Heather T Gold, Naveen Subhas
OBJECTIVE: The purpose of this study was to determine the cost-effectiveness of landmark-based and image-guided intraarticular steroid injections for the initial treatment of a population with adhesive capsulitis. MATERIALS AND METHODS: A decision analytic model from the health care system perspective over a 6-month time frame for 50-year-old patients with clinical findings consistent with adhesive capsulitis was used to evaluate the incremental cost-effectiveness of three techniques for administering intraarticular steroid to the glenohumeral joint: landmark based (also called blind), ultrasound guided, and fluoroscopy guided...
April 9, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29609595/capture-of-intraocular-lens-optic-by-residual-capsular-opening-in-secondary-implantation-long-term-follow-up
#13
Tian Tian, Chunli Chen, Haiying Jin, Lyu Jiao, Qi Zhang, Peiquan Zhao
BACKGROUND: To introduce a novel surgical technique for optic capture by residual capsular opening in secondary intraocular lens (IOL) implantation and to report the outcomes of a long follow-up. METHODS: Twenty patients (20 eyes) who had received secondary IOL implantation with the optic capture technique were retrospectively reviewed. We used the residual capsular opening for capturing the optic and inserted the haptics in the sulcus during surgery. Baseline clinical characteristics and surgical outcomes, including best-corrected visual acuity (BCVA), refractive status, and IOL position were recorded...
April 2, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29581969/analgesic-effect-of-extracorporeal-shock-wave-treatment-combined-with-fascial-manipulation-theory-for-adhesive-capsulitis-of-the-shoulder-a-retrospective-study
#14
Xiangnan Yuan, Fenghua Zhou, Lixin Zhang, Zhiqiang Zhang, Jianjun Li
Objectives: This study aims to explore whether extracorporeal shockwave treatment (ESWT) based on the theory of fascial manipulation (FM) at select treatment points is superior to traditional local ESWT for pain relief in adhesive capsulitis of the shoulder. Methods: Data from patients with adhesive capsulitis of the shoulder who received weekly ESWT according to fascial manipulation theory (ESWT-FM) or local extracorporeal shockwave treatment (L-ESWT) during a 5-week treatment period were evaluated...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29576637/complications-associated-with-locking-plate-of-proximal-humerus-fractures
#15
REVIEW
Venkat Kavuri, Blake Bowden, Neil Kumar, Doug Cerynik
Proximal humerus fractures constitute a significant percentage of fragility fractures. The growing use of locking plate has helped treat this problem, but at the same time has brought about complications. Past systematic reviews have documented these complications, however a large number of recent studies have been published since, reporting their own complication rates with different techniques. This study reviews the current complications associated with locking plate of proximal humerus fractures as well as methods to reduce them...
March 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29575998/human-endometrial-reconstitution-from-somatic-stem-cells-the-importance-of-niche-like-cells
#16
Nuria López-Pérez, Claudia Gil-Sanchis, Hortensia Ferrero, Amparo Faus, Ana Díaz, Antonio Pellicer, Irene Cervelló, Carlos Simón
Endometrial regeneration has long been proposed to be mediated by stem cells, but the isolation of endometrial stem cells has been hampered by a lack of validated markers. Specific markers would enable isolation of these stem cells, thereby promoting advancements in regenerative medicine for the treatment of endometrial diseases and dysfunctions. We sought to investigate the regenerative ability of human endometrial positive for sushi domain containing 2/intercellular adhesion molecule 1 (SUSD2+ /ICAM1+ ) cells and Side Population cell lines in a xenograft mice model...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29570844/maintenance-of-redox-balance-by-antioxidants-in-hemolymph-of-the-greater-wax-moth-galleria-mellonella-larvae-during-encapsulation-response
#17
Ekaterina V Grizanova, Alexandra D Semenova, Denis A Komarov, Ekaterina A Chertkova, Irina A Slepneva, Ivan M Dubovskiy
The lipid peroxidation process in hemocytes, activities of phenoloxidase and key enzymatic antioxidants (superoxide dismutase, glutathione-S-transferase, catalase) and nonenzymatic antioxidants (thiols, ascorbate) in hemolymph of the greater wax moth Galleria mellonella L. (Lepidoptera: Pyralidae) were studied during the encapsulation process of nylon implants. It has been established that as soon as 15 min after piercing a cuticle with the implant, a capsule is formed on its surface. Active melanization of the capsule has been shown to last for 4 h...
March 23, 2018: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/29567961/rac1-in-podocytes-promotes-glomerular-repair-and-limits-the-formation-of-sclerosis
#18
Rin Asao, Takuto Seki, Miyuki Takagi, Hiroyuki Yamada, Fumiko Kodama, Yoshiko Hosoe-Nagai, Eriko Tanaka, Juan Alejandro Oliva Trejo, Kanae Yamamoto-Nonaka, Yu Sasaki, Teruo Hidaka, Takashi Ueno, Motoko Yanagita, Yusuke Suzuki, Yasuhiko Tomino, Katsuhiko Asanuma
Rac1, a Rho family member, is ubiquitously expressed and participates in various biological processes. Rac1 expression is induced early in podocyte injury, but its role in repair is unclear. To investigate the role of Rac1 expression in podocytes under pathological conditions, we used podocyte-specific Rac1 conditional knock-out (cKO) mice administered adriamycin (ADR), which causes nephrosis and glomerulosclerosis. Larger areas of detached podocytes, more adhesion of the GBM to Bowman's capsule, and a higher ratio of sclerotic glomeruli were observed in Rac1 cKO mice than in control mice, whereas no differences were observed in glomerular podocyte numbers in both groups after ADR treatment...
March 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29567320/ultrasound-guided-coracohumeral-ligament-release
#19
K Yukata, T Goto, Toshinori Sakai, A Sakai, H Fujii, Koichi Sairyo, J Hamawaki, N Yasui
Long-term follow-up of patients with adhesive capsulitis (AC) reveals that approximately half of them suffer from a limited range of shoulder motion, particularly external and/or internal rotation. We report the surgical technique and short-term clinical outcomes of ultrasound-guided release of the thickened coracohumeral (CH) ligament in 8 patients (9 shoulders) with AC. Passive external rotation with the arm by the side significantly increased from an average of 18° preoperatively to 47° immediately after CH ligament release...
March 19, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29560034/can-we-improve-the-outcome-of-hydrodilatation-for-adhesive-capsulitis
#20
David N Haughton, Simon Barton, Erin Meenan, Rakesh Mehan, Philip Wykes, James Warner, Emma Mulgrew
Background: Hydrodilatation (HD) has been shown to improve pain and function in patients with adhesive capsulitis (AC). There is no consensus concerning how HD should be performed or what volume should be injected. It has distinct advantages compared to surgery; however, it is a painful procedure and is often poorly tolerated. Methods: We retrospectively reviewed all patients referred for HD over a 2.5-year period aiming to assess whether volume injected influences outcome...
April 2018: Shoulder & Elbow
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