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https://www.readbyqxmd.com/read/28526810/bioinformatics-and-in-vitro-experimental-analyses-identify-the-selective-therapeutic-potential-of-interferon-gamma-and-apigenin-against-cervical-squamous-cell-carcinoma-and-adenocarcinoma
#1
Pei-Ming Yang, Chia-Jung Chou, Ssu-Hsueh Tseng, Chien-Fu Hung
The clinical management and treatment of cervical cancer, one of the most commonly diagnosed cancers and a leading cause of cancer-related female death, remains a huge challenge for researchers and health professionals. Cervical cancer can be categorized into two major subtypes: common squamous cell carcinoma (SCC) and adenocarcinoma (AC). Although it is a relatively rare histological subtype of cervical cancer, there has been a steady increase in the incidences of AC. Therefore, new strategies to treat cervical cancer are urgently needed...
May 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28495329/dynamics-of-the-driving-force-during-the-normal-vocal-fold-vibration-cycle
#2
Philippe Henri DeJonckere, Jean Lebacq, Ingo R Titze
Intraglottal pressure is the driving force of vocal fold vibration. Theoretically, simultaneous quantification of glottal area and transglottal airflow allows the calculation of the intraglottal pressure waveform during a single vibration cycle. In this study, we show that, by combining photoglottography (transglottal light transmission) and airflow (Rothenberg mask) measurements during sustained vocal emissions in vivo, the intraglottal pressure wave can be approximated in a way similar to what has been done in models...
May 8, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28493819/the-choice-of-freely-preferred-cadence-by-trained-nonprofessional-cyclists-may-not-be-characterized-by-mechanical-efficiency
#3
Yitzhak Weinstein, Ron Mor-Unikowski, Shachar Nice, Shraga Hocherman, Omri Inbar
BACKGROUND: Most cycling studies involve professional cyclists. Because training may affect riding style, it is of interest to determine the physiological basis for the personal choice of cycling cadence in nonprofessional cyclists. METHODS: Eleven nonprofessional (5.2±1.7-year-riding experience) male road cyclists, aged 35.0±11.0 years, underwent four separate laboratory test sessions. The first two sessions included habituation, anthropometry, V˙O2max,$\dot V{{\text{O}}_{\text{2}}}{\text{max}},$ and lactate threshold (LaTH) measurements...
May 11, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28481816/changes-in-and-determinants-of-quality-of-life-in-patients-with-advanced-non-small-cell-lung-cancer-undergoing-initial-chemotherapy
#4
Yu-Lee Dai, Cheng-Ta Yang, Kang-Hua Chen, Siew-Tzuh Tang
BACKGROUND: Few studies have evaluated completely the changes in quality of life (QOL) that occur from pretreatment through the first four consecutive cycles of chemotherapy or determined its determinants in patients with advanced non-small-cell lung cancer (NSCLC). PURPOSE: The aim of this study was to explore the changes to and determinants of QOL in patients with advanced NSCLC under initial chemotherapy from pretreatment through Cycle 4 of chemotherapy. METHODS: The QOL of 139 patients with advanced NSCLC was assessed from prechemotherapy through Cycle 4 of chemotherapy...
June 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28447864/the-use-of-cyproterone-acetate-ethinyl-estradiol-in-hyperandrogenic-skin-symptoms-a-review
#5
J Bitzer, T Römer, A Lopes da Silva Filho
INTRODUCTION: Hyperandrogenism affects approximately 10-20% of women of reproductive age. Hyperandrogenic skin symptoms such as hirsutism, acne, seborrhea and alopecia are associated with significant quality of life and psychological impairment. Women with abnormalities in androgen metabolism may have accompanying anovulation and/or polycystic ovary syndrome (PCOS), both of which have reproductive and metabolic implications if left untreated. Cyproterone acetate (CPA), combined with ethinylestradiol (EE), is indicated for the treatment of moderate to severe acne related to androgen-sensitivity (with or without seborrhea) and/or hirsutism, in women of reproductive age...
April 27, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28446141/a-mobile-application-of-breast-cancer-e-support-program-versus-routine-care-in-the-treatment-of-chinese-women-with-breast-cancer-undergoing-chemotherapy-study-protocol-for-a-randomized-controlled-trial
#6
Jiemin Zhu, Lyn Ebert, Xiangyu Liu, Sally Wai-Chi Chan
BACKGROUND: Women with breast cancer undergoing chemotherapy suffer from a number of symptoms and report receiving inadequate support from health care professionals. Innovative and easily accessible interventions are lacking. Breast Cancer e-Support is a mobile Application program (App) that provides patients with individually tailored information and a support group of peers and health care professionals. Breast Cancer e-Support aims to promote women's self-efficacy, social support and symptom management, thus improving their quality of life and psychological well-being...
April 26, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28433454/a-randomized-comparison-of-three-chest-compression-techniques-and-associated-hemodynamic-effect-during-infant-cpr-a-randomized-manikin-study
#7
Jacek Smereka, Lukasz Szarpak, Antonio Rodríguez-Núñez, Jerzy R Ladny, Steve Leung, Kurt Ruetzler
INTRODUCTION: Pediatric cardiac arrest is an uncommon but critical life-threatening event requiring effective cardiopulmonary resuscitation. High-quality cardio-pulmonary resuscitation (CPR) is essential, but is poorly performed, even by highly skilled healthcare providers. The recently described two-thumb chest compression technique (nTTT) consists of the two thumbs directed at the angle of 90° to the chest while having the fingers fist-clenched. This technique might facilitate adequate chest-compression depth, chest-compression rate and rate of full chest-pressure relief...
April 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28422523/can-the-lamberts-submaximal-cycle-test-reflect-overreaching-in-professional-cyclists
#8
Lieselot Decroix, Robert P Lamberts, Romain Meeusen
PURPOSE: The Lamberts and Lambert Submaximal Cycle Test (LSCT) consists of 3 stages during which cyclist's cycle for 6 minutes at 60%, 6 minutes at 80% and 3 minutes at 90% of their maximal heart rate, followed by one-minute recovery. It was the aim of this study to determine if the LSCT is able to reflect a state of functional overreaching in professional female cyclists during an 8-day training camp and the following recovery days. METHODS: Six professional female cyclists performed an LSCT on day 1, day 5 and day 8 of the training camp and 3 days after the training camp...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28412667/nurses-perceptions-of-the-impact-of-team-based-learning-participation-on-learning-style-team-behaviours-and-clinical-performance-an-exploration-of-written-reflections
#9
Elizabeth Oldland, Judy Currey, Julie Considine, Josh Allen
Team-Based Learning (TBL) is a teaching strategy designed to promote problem solving, critical thinking and effective teamwork and communication skills; attributes essential for safe healthcare. The aim was to explore postgraduate student perceptions of the role of TBL in shaping learning style, team skills, and professional and clinical behaviours. An exploratory descriptive approach was selected. Critical care students were invited to provide consent for the use for research purposes of written reflections submitted for course work requirements...
May 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28410172/adolescent-and-young-adult-cancer-survivorship-educational-programming-a-qualitative-evaluation
#10
Deborah Vollmer Dahlke, Kayla Fair, Yan Alicia Hong, Debra Kellstedt, Marcia G Ory
BACKGROUND: This program evaluation considers the need for increased professional and patient education for adolescent and young adult (AYA) cancer survivorship. Due to the high incidence of late effects of cancer treatment among AYA cancer survivors, knowledge sharing and communications are needed throughout the transition from cancer care into community care. AYA survivors are likely to need developmentally appropriate psychosocial care as well as extensive follow-on surveillance by physicians who are educated and aware of the likely chronic conditions and late effects that may occur in these patients...
February 10, 2017: JMIR Cancer
https://www.readbyqxmd.com/read/28387818/ethics-and-the-cardiac-pacemaker-more-than-just-end-of-life-issues
#11
Katrina Hutchison, Robert Sparrow
For many years, ethical debate about pacemakers has focused on whether and under what circumstances they may be turned off in end of life care. Several other important ethical issues have been neglected, perhaps because the dilemmas they pose for cardiologists are not so immediate. These include: potential conflicts of interest, particularly those arising from the role of industry employed allied professionals (IEAPs) in pacemaker care; unanticipated impacts of commercial competition and the device improvement cycle; risks associated with remotely accessible software; equity in access to healthcare; and questions about reuse of explanted pacemakers in low and middle income countries...
April 6, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28380129/factors-associated-with-user-satisfaction-regarding-treatment-offered-in-brazilian-primary-health-care
#12
Ane Polline Lacerda Protasio, Luciano Bezerra Gomes, Liliane Dos Santos Machado, Ana Maria Gondim Valença
The Program for Access and Quality Improvement in Primary Care (PMAQ-AB) aimed to improve healthcare public service quality. The purpose of this study was to identify the main factors that influence user satisfaction in Brazilian primary health care services. This research was carried out using secondary data from the first cycle of the PMAQ-AB. A cluster analysis was carried out to find the dependent variable of user satisfaction; and logistic regression was applied in order to obtain the decision model. From the resulting regression model, two factors can be highlighted as regards influencing user satisfaction in Brazil: the user's perception that the team did not attempt to address their needs/problems within the health unit; and the user not feeling respected by the professionals in relation to cultural habits, customs, and religion or only sometimes feeling so...
March 30, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28378431/left-ventricular-biomechanics-in-professional-football-players
#13
T G von Lueder, A Hodt, G F Gjerdalen, K Steine
Chronic exercise induces adaptive changes of left ventricular (LV) ejection and filling capacities which may be detected by novel speckle-tracking echocardiography (STE) and tissue Doppler imaging (TDI)-based techniques. A total of 103 consecutive male elite Norwegian soccer players and 46 age-matched healthy controls underwent echocardiography at rest. STE was used to assess LV torsional mechanics and LV systolic longitudinal strain (LS). Diastolic function was evaluated by trans-mitral blood flow, mitral annular velocities by TDI, and LV inflow propagation velocity by color M-mode...
April 4, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28374724/-the-planning-and-evaluation-of-the-effectiveness-of-rehabilitation-of-the-patients-presenting-with-osteoarthritis-application-of-the-core-set-of-the-international-classification-of-functioning-disability-and-health
#14
G N Ponomarenko, A V Shoshmin, Ya K Besstrashnova, I V Cherkashina
This article was designed to report the results of analysis of the comprehensive rehabilitation programs for the patients presenting with osteoarthritis. The analysis was based on the Core Set of the International Classification of Functioning, Disability and Health (ICF Core Set). The authors carried out the evaluation of the effectiveness of rehabilitation for two groups of the patients suffering from osteoarthritis who had previously undergone the combined treatment based at different healthcare facilities (an in-patient clinic, a spa and health resort)...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28369023/collaborate%C3%A2-part-iv-ramping-up-competency-based-performance-management
#15
Teresa M Treiger, Ellen Fink-Samnick
PURPOSE/OBJECTIVES: The purpose of this fourth part of the COLLABORATE© article series provides an expansion and application of previously presented concepts pertaining to the COLLABORATE paradigm of professional case management practice. The model is built upon a value-driven foundation that: PRIMARY PRACTICE SETTING(S):: Applicable to all health care sectors where case management is practiced. FINDINGS/CONCLUSIONS: As an industry, health care continues to evolve...
May 2017: Professional Case Management
https://www.readbyqxmd.com/read/28362466/using-research-findings-to-design-an-evidence-based-practice-curriculum
#16
Helen K Burns, Lois Noonan, Deborah Poskus Jenkins, Lisa Marie Bernardo
Evidence from a system-wide research study highlighted strengths and weaknesses in evidence-based practice (EBP) implementation, beliefs, and organizational readiness. To address this evidence, a curriculum was developed within the context of the shared governance and EBP models for nursing practice. The curriculum, Evidence-Based Practice: Clinical Applications in Professional Nursing Practice, consists of five modules that provide the knowledge, skills, and abilities relative to each step of EBP. The learning approach incorporates classroom- and unit-based education, facilitated by EBP curriculum mentors...
April 1, 2017: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/28358788/an-application-of-business-process-management-to-health-care-facilities
#17
Mohsen M D Hassan
The purpose of this article is to help health care facility managers and personnel identify significant elements of their facilities to address, and steps and actions to follow, when applying business process management to them. The ABPMP (Association of Business Process Management Professionals) life-cycle model of business process management is adopted, and steps from Lean, business process reengineering, and Six Sigma, and actions from operations management are presented to implement it. Managers of health care facilities can find in business process management a more comprehensive approach to improving their facilities than Lean, Six Sigma, business process reengineering, and ad hoc approaches that does not conflict with them because many of their elements can be included under its umbrella...
April 2017: Health Care Manager
https://www.readbyqxmd.com/read/28341932/-cross-sectional-field-pain-medicine-q14-the-mainz-model-development-of-the-pain-medicine-curriculum-in-the-standard-study-course-at-the-university-medical-school-of-the-johannes-gutenberg-university-mainz
#18
S Kurz, H Buggenhagen, R Schwab, R Laufenberg-Feldmann
BACKGROUND AND OBJECTIVES: Following the amendment of the Medical Licensure Act (ÄAppO) in 2012, pain medicine was introduced as a mandatory subject for students during undergraduate medical training. Medical schools were required to define and to implement adequate curricular and formal teaching structures based on interdisciplinary and multiprofessional requirements according to the curriculum for pain medicine of the German Pain Society. These aspects were considered in the new interdisciplinary curriculum for pain medicine, the so-called Mainz model...
March 24, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28323542/organized-abuse-in-adulthood-survivor-and-professional-perspectives
#19
Michael Salter
This paper reports on the preliminary findings of a qualitative study of Australian women disclosing organized abuse in adulthood and the mental health professionals who treat them. Drawing on interviews with survivors and mental health professionals, the paper analyses the fraught relationship between mental health and physical safety for adults subject to organized abuse. The therapeutic progress of adult organized abuse victims can be disrupted by ongoing threats, stalking, and group violence, which in turn reinforces the dissociative responses and pathological attachments that render them vulnerable to revictimization...
May 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28300990/analysis-of-the-attributes-of-primary-health-care-using-the-electronic-medical-records-in-the-city-of-rio-de-janeiro
#20
Daniel Soranz, Luiz Felipe Pinto, Luiz Antonio Bastos Camacho
Epidemiology plays a strategic role at this stage of the policy cycle, contributing to goal setting, resource allocation and use of information systems. In 2009, the Municipal Health Secretariat of Rio de Janeiro initiated a reform of the health care model under the main influence the Primary Health Care concept. This study evaluates the trend of selected pay-for-performance indicators that measure the health care process in the city's PHC. This a study on repeated panels, from the administrative and clinical records of electronic medical records in the period from 2012 to 2016...
March 2017: Ciência & Saúde Coletiva
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