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https://www.readbyqxmd.com/read/29915915/post-embolization-neurological-syndrome-after-embolization-for-intracranial-and-skull-base-tumors-transient-exacerbation-of-neurological-symptoms-with-inflammatory-responses
#1
Yujiro Tanaka, Takao Hashimoto, Daisuke Watanabe, Hirofumi Okada, Daichi Kato, Shigeru Aoyagi, Jiro Akimoto, Michihiro Kohno
PURPOSE: Pre-operative embolization is an effective treatment strategy for hypervascular intracranial and skull base tumors. However, neurological complications resulting from tumor swelling, cranial nerve ischemia, or hemorrhage can occur after embolization. The purpose of this study was to examine the relationship between neurological complications following pre-operative embolization and minor adverse events including fever, headache, or increasing inflammation, which are common after embolization for abdominal tumors (i...
June 18, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29913626/vasoactive-intestinal-peptide-vip-and-pituitary-adenylate-cyclase-activating-polypeptide-pacap-in-the-circulation-after-sumatriptan
#2
Jakob Møller Hansen, Jan Fahrenkrug, Jesper Petersen, Troels Wienecke, Karsten Skovgaard Olsen, Messoud Ashina
Background and purpose The origin of migraine pain is still elusive, but increasingly researchers focus on the neuropeptides in the perivascular space of cranial vessels as important mediators of nociceptive input during migraine attacks. The parasympathetic neurotransmitters, pituitary adenylate cyclase activating peptide-38 (PACAP38) and vasoactive intestinal peptide (VIP) may be released from parasympathetic fibres and activate sensory nerve fibres during migraine attacks. Triptans are effective and well tolerated in acute migraine management but the exact mechanism of action is still debated...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912825/how-well-does-intraoperative-audiologic-monitoring-predict-hearing-outcome-during-middle-fossa-vestibular-schwannoma-resection
#3
Daniel Q Sun, C Blake Sullivan, Raymund W Kung, Megan Asklof, Marlan R Hansen, Bruce J Gantz
OBJECTIVE: To evaluate the association between signal changes during intraoperative audiologic monitoring and postoperative audiometric outcome in patients undergoing vestibular schwannoma (VS) resection via middle cranial fossa (MCF) approach. STUDY DESIGN: Retrospective chart review. SETTING: Academic tertiary referral center. PATIENTS: One hundred twenty-six consecutive patients (mean age 48.6 yrs, range 16-67; mean tumor size 9...
June 15, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29912183/ocular-kinematics-measured-by-in-vitro-stimulation-of-the-cranial-nerves-in-the-turtle
#4
Maria Cano Garcia, Steven C Nesbit, Chi C Le, James R Dearworth
After animals are euthanized, their tissues begin to die. Turtles offer an advantage because of a longer survival time of their tissues, especially when compared to warm-blooded vertebrates. Because of this, in vitro experiments in turtles can be performed for extended periods of time to investigate the neural signals and control of their target actions. Using an isolated head preparation, we measured the kinematics of eye movements in turtles, and their modulation by electrical signals carried by cranial nerves...
June 2, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29911581/real-time-ultrasound-guided-infraorbital-nerve-block-to-treat-trigeminal-neuralgia-using-a-high-concentration-of-tetracaine-dissolved-in-bupivacaine
#5
Kenichi Takechi, Amane Konishi, Kotaro Kikuchi, Shiho Fujioka, Tomomi Fujii, Toshihiro Yorozuya, Koh Kuzume, Takumi Nagaro
Background Trigeminal neuralgia is a neuropathic disorder characterized by episodes of intense pain in the face. Drug therapy is the first choice of treatment. However, in cases where drug therapy are contraindicated due to side effects, patients can get pain relief from lengthy neurosurgical procedures. Alternatively, a peripheral trigeminal nerve block can be easily performed in an outpatient setting. Therefore it is a useful treatment option for the acute paroxysmal period of TN in patients who cannot use drug therapy...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911245/tumor-associated-hemorrhage-in-patients-with-vestibular-schwannoma
#6
Xiang Yang, Jiagang Liu, Yuekang Zhang, Seidu A Richard
OBJECT: Intratumoral hemorrhage (ITH) associated with vestibular schwannomas (VS) is very rare. We retrospectively analyzed VS patients presenting with ITH in our department to further gain a better understanding of this uncommon clinical presentation. METHODS: We treated seven patients who had VS presenting with ITH between January 2012 and June 2017. All the patients had preoperative computed tomography (CT), computed tomography angiography (CTA), and magnetic resonance imaging(MRI) done which aided in the radiological diagnosis as well as postoperative MRI to confirm the resection extent of the VS...
June 18, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29911023/cavernous-sinus-syndrome-in-dogs-and-cats-case-series-2002-2015
#7
Aslynn M Jones, Ellison Bentley, Helena Rylander
The cavernous sinus (CS) is a paired venous sinus that runs along either side of the pituitary gland on the floor of the calvarium. Cavernous sinus syndrome (CSS) refers to deficits in more than one of the cranial nerves III, IV, V, and VI, as they are in close association in this region. The purpose of this study was to identify the presenting complaints, neurologic findings, diagnosis, and outcomes in dogs and cats with confirmed cavernous sinus syndrome (CSS). Medical records between 2002 and 2015 were reviewed...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29910862/vestibular-paroxysmia-in-vestibular-neuritis-a-case-report
#8
Michele Ori, Valeria Gambacorta, Giampietro Ricci, Mario Faralli
The term vestibular paroxysmia (VP) was introduced for the first time by Brandt and Dieterich in 1994. In 2016, the Barany Society formulated the International Classification of VP, focusing in particular on the number and duration of attacks, on the differential diagnosis and on the therapy. Ephaptic discharges in the proximal part of the eighth cranial nerve, which is covered by oligodendrocytes, are assumed to be the neural basis of VP. We report the first case in literature of an onset of symptoms and signs typical of VP in a young man following acute unilateral vestibular loss not combined with auditory symptoms...
March 6, 2018: Audiology Research
https://www.readbyqxmd.com/read/29910746/brain-stimulation-in-alzheimer-s-disease
#9
REVIEW
Chun-Hung Chang, Hsien-Yuan Lane, Chieh-Hsin Lin
Brain stimulation techniques can modulate cognitive functions in many neuropsychiatric diseases. Pilot studies have shown promising effects of brain stimulations on Alzheimer's disease (AD). Brain stimulations can be categorized into non-invasive brain stimulation (NIBS) and invasive brain stimulation (IBS). IBS includes deep brain stimulation (DBS), and invasive vagus nerve stimulation (VNS), whereas NIBS includes transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), electroconvulsive treatment (ECT), magnetic seizure therapy (MST), cranial electrostimulation (CES), and non-invasive VNS...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29909380/schwannomatosis-a-genetic-and-epidemiological-study
#10
D Gareth Evans, Naomi L Bowers, Simon Tobi, Claire Hartley, Andrew J Wallace, Andrew T King, Simon K W Lloyd, Scott A Rutherford, Charlotte Hammerbeck-Ward, Omar N Pathmanaban, Simon R Freeman, John Ealing, Mark Kellett, Roger Laitt, Owen Thomas, Dorothy Halliday, Rosalie Ferner, Amy Taylor, Chris Duff, Elaine F Harkness, Miriam J Smith
OBJECTIVES: Schwannomatosis is a dominantly inherited condition predisposing to schwannomas of mainly spinal and peripheral nerves with some diagnostic overlap with neurofibromatosis-2 (NF2), but the underlying epidemiology is poorly understood. We present the birth incidence and prevalence allowing for overlap with NF2. METHODS: Schwannomatosis and NF2 cases were ascertained from the Manchester region of England (population=4.8 million) and from across the UK. Point prevalence and birth incidence were calculated from regional birth statistics...
June 16, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29909215/modeling-neurodegeneration-in-patients-with-visual-pathway-tumors-by-retinal-optical-coherence-tomography
#11
Ana Banc, Cristina Stan, Alexandra-Stefania Berghe, Tudor Catalin Drugan, Ioan-Stefan Florian
OBJECTIVE: Optical coherence tomography (OCT) is a non-invasive high-resolution imaging technique which was suggested to be a powerful biomarker of neurodegeneration. The objective of our study is to assess the pattern of retinal OCT changes in patients with visual pathway tumors. METHODS: A prospective clinical study was conducted and patients with single cerebral tumors with potential of compression on the visual pathway were included. Patients with multiple and/or metastatic tumors were excluded...
June 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29907154/temporal-changes-in-macrophage-phenotype-after-peripheral-nerve-injury
#12
Joy E Tomlinson, Emilija Žygelytė, Jennifer K Grenier, Michael G Edwards, Jonathan Cheetham
BACKGROUND: Macrophages play a key role in peripheral nerve repair and demonstrate complex phenotypes that are highly dependent on microenvironmental cues. METHODS: We determined temporal changes in macrophage gene expression over time using RNA sequencing after fluorescence-activated cell sorting (FACS) macrophage populations from injured peripheral nerve. We identified key upstream regulators and dominant pathways using ingenuity pathway analysis and confirmed these changes with NanoString technology...
June 15, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29905637/primary-extracranial-meningioma-of-the-lacrimal-sac-fossa
#13
Phillip M Radke, Peter A Herreid, Bryan S Sires
Primary extracranial meningioma is a rare tumor, unlike its common intracranial counterpart. Infrequently found in the head and neck region, it can cause local or neurologic symptoms depending on its location and interaction with cranial nerves. While uncommon, it is an important diagnosis to have on the differential of periorbital lesions as surgical removal and prognosis are generally good. The authors present the first report of a patient with primary extracranial meningioma originating in the lacrimal sac fossa...
June 13, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29905156/two-cases-of-opercular-myoclonic-anarthric-status-epilepticus
#14
Amaia Muñoz-Lopetegi, Gorka Fernández García de Eulate, Jon Rodríguez-Antigüedad Muñoz, Alberto Bergareche, Juan José Poza
Opercular myoclonic-anarthric status epilepticus (OMASE) is a rare form of epilepsia partialis continua presenting as fluctuating dysarthria, or even anarthria. The condition is caused by an epileptogenic lesion involving the opercular cortex of either hemisphere. Speech impairment is secondary to bilateral epileptic activity affecting the glossopharyngeal muscles. This bilateral nature of the condition is due to the fact that innervation of cranial nerves V, VII, IX, X and XII from the opercular area of the primary motor cortex is bilateral...
June 15, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29904898/relapsing-painful-ophthalmoplegic-neuropathy-no-longer-a-migraine-but-still-a-headache
#15
REVIEW
Stacy V Smith, Nathaniel M Schuster
PURPOSE OF REVIEW: Recurrent painful ophthalmoplegic neuropathy (RPON), formerly known as ophthalmoplegic migraine, is an uncommon disorder with repeated episodes of ocular cranial nerve neuropathy associated with ipsilateral headache. This review discusses the clinical presentation, current understanding of the pathophysiology, key differential diagnoses, and evaluation and treatment of RPON. RECENT FINDINGS: The literature is limited due to the rarity of the disorder...
June 14, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29899775/extensive-cranial-nerves-involvement-in-neurofibromatosis-a-rare-presentation
#16
Ashutosh Gupta, Charu Gupta, Monika Sachan, Sandeep Singh
Neurofibromatosis type 2 is a rare neurocutaneous syndrome characterized by the development of multiple nervous system tumors. This disorder is also called multiple inherited schwannomas, meningiomas, and ependymomas syndrome. In this report, we discuss the clinical and magnetic resonance imaging findings in a 17-year-old patient with neurofibromatosis type 2, who had extensive cranial nerves involvement (3rd-12th cranial nerves) along with spinal involvement. It is very rare to find tumors affect nearly all cranial nerves (namely 3rd-12th nerves), and their association with meningiomas and intramedullary spinal cord tumors in the same patient...
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29894453/gradenigo-syndrome-induced-by-suppurative-otitis-media
#17
Nazim Bozan, Ufuk Düzenli, Abdulzaziz Yalinkilic, Abdurrahman Ayral, Mehmet Parlak, Mahfuz Turan, Ahmet Faruk Kiroglu
Gradenigo syndrome was defined as a clinical triad of otitis media, severe orbito-facial pain, and ipsilateral sixth cranial nerve palsy. It may occur as a complication of either acute or chronic otitis media. Herein, we will report a case of Gradenigo syndrome induced by suppurative chronic otitis media that was promptly diagnosed and aggressively treated.
June 11, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29892257/focused-neuro-otological-review-of-superficial-siderosis-of-the-central-nervous-system
#18
Aran Yoo, Jonathan Jou, Jeffrey D Klopfenstein, Jorge C Kattah
Background: Infratentorial siderosis (iSS) is a progressive degenerative disorder targeting primarily the cerebellum and cranial nerve eighth; therefore, progressive ataxia and its neuro-otological findings are common. Toxicity from hemosiderin involves selectively vulnerable neurons and glia in these posterior fossa structures. Other neurologic findings may be present, though our focus relates to the cochlea-vestibular cerebellar involvement. Radiographic evidence of siderosis may be the result of recurrent, albeit covert bleeding in the subarachnoid space, or the consequence of an overt post-traumatic or aneurysmal subarachnoid hemorrhage (SAH)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29890210/the-rostral-medulla-of-bullfrog-tadpoles-contains-critical-lung-rhythmogenic-and-chemosensitive-regions-across-metamorphosis
#19
Mitchell D Reed, Kimberly E Iceman, Michael B Harris, Barbara E Taylor
The development of amphibian breathing provides insight into vertebrate respiratory control mechanisms. Neural oscillators in the rostral and caudal medulla drive ventilation in amphibians, and previous reports describe ventilatory oscillators and CO2 sensitive regions arise during different stages of amphibian metamorphosis. However, inconsistent findings have been enigmatic, and make comparisons to potential mammalian counterparts challenging. In the current study we assessed amphibian central CO2 responsiveness and respiratory rhythm generation during two different developmental stages...
June 8, 2018: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/29889789/does-a-fundal-fluid-cap-predict-successful-hearing-preservation-in-vestibular-schwannoma-resections-via-the-middle-cranial-fossa-approach
#20
Daniel Q Sun, Raymond W Kung, Marlan R Hansen, Bruce J Gantz
OBJECTIVE: To determine the association between radiographic cerebrospinal fluid (CSF) cap in the lateral internal auditory canal (IAC) and likelihood of successful hearing preservation in middle cranial fossa (MCF) vestibular schwannoma (VS) surgery. STUDY DESIGN: Retrospective chart review. SETTING: Academic tertiary referral center. PATIENTS: One hundred thirty-eight consecutive patients (mean age/standard deviation, SD, 50/11 yr) who underwent MCF VS resection...
July 2018: Otology & Neurotology
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