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https://www.readbyqxmd.com/read/29028179/reconstructing-one-articulated-networks-with-distance-matrices
#1
Kuang-Yu Chang, Yun Cui, Siu-Ming Yiu, Wing-Kai Hon
Given a distance matrix M that represents evolutionary distances between any two species, an edge-weighted phylogenetic network N is said to satisfy M if between any pair of species, there exists a path in N with a length equal to the corresponding entry in M. In this article, we consider a special class of networks called a one-articulated network, which is a proper superset of galled trees. We show that if the distance matrix M is derived from an ultrametric one-articulated network N (i.e., for any species X and Y, the entry [Formula: see text] is equal to the shortest distance between X and Y in N), we can re-construct a network that satisfies M in [Formula: see text] time, where n denotes the number of species; further, the reconstructed network is guaranteed to be the simplest, in a sense that the number of hybrid nodes is minimized...
October 13, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29028131/a-motion-analysis-protocol-for-kinematic-assessment-of-poly-articulated-prosthetic-hands-with-cosmetic-gloves
#2
Andrea Giovanni Cutti, Francesca Cordella, Giulia D'Amico, Rinaldo Sacchetti, Angelo Davalli, Eugenio Guglielmelli, Loredana Zollo
To provide upper-limb amputees with devices that best fit their needs and to test innovative solutions, it is necessary to quantitatively appraise a device performance with rigorous measurement methods. The aim of this work was to define an optimal motion analysis protocol, suitable for optoelectronic systems, to measure the kinematics of poly-articulated hands even when covered by a cosmetic glove. This is a fundamental aspect, because gloves can decrease device speed and range of motion and, ultimately, patients' acceptance of the artificial limb...
October 13, 2017: Artificial Organs
https://www.readbyqxmd.com/read/29024032/que-faire-a-bioeconomy-and-solar-energy-institute-at-italy-s-research-council-in-the-context-of-the-global-transition-to-the-solar-economy
#3
Mario Pagliaro, Francesco Meneguzzo
Driven by insight for which new research and education requires new institutional organisation, and drawing on two decades of research and educational efforts, we devise the profile and activities of a new bioeconomy and solar energy institute at Italy's Research Council. We further articulate the institute's activities suggesting avenues on how to deploy sound and giving more useful research, education and policy advice in these crucial fields for making tomorrow's common development sustainable. The outcomes of the study are of general interest, because the transition to a solar economy is of intrinsic global nature and the challenges involved are similar in many countries...
October 12, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29023298/appraisal-of-function-after-rehabilitation-with-tongue-prosthesis
#4
Pankaj Kharade, Kanchan Dholam, Gurmit Bachher
STATEMENT OF THE PROBLEM: Prosthetic rehabilitation following total glossectomy is very complex procedure from clinical as well as laboratory point of view. The basic objective of prosthodontic rehabilitation is to deliver a comfortable as well as esthetically suitable prosthesis, which restores the impaired speech and deglutition function. PURPOSE: Prosthetic rehabilitation of patients after total glossectomy with tongue prosthesis to evaluate improvement in speech as well as swallowing function...
October 11, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29023294/cleft-lip-and-palate-demographic-patterns-and-the-associated-communication-disorders
#5
Firas S D Alfwaress, Fadwa A Khwaileh, Ma'amon A Rawashdeh, Mahmoud A Alomari, Mohammad S Nazzal
PURPOSE: This study investigated demographical characteristics, health status, and associated communication disorders in patients with orofacial clefts (OFCs) in Northern Jordan. METHODS: A retrospective study of 226 cleft patients and their families was carried out between March 2012 and September 2016 at the Speech and Hearing Clinic and the Maxillofacial Center at King Abdullah University Hospital. Data were collected by interviewing patients and caregivers, having patients or caregiver to complete a questionnaire and reviewing the patient's medical records...
October 11, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29021886/antibiotic-laden-arthroplasty-with-a-novel-design-of-cement-mould-and-metallic-endoskeleton-for-treatment-of-hip-infection-an-inexpensive-alternative-a-preliminary-report-of-two-cases
#6
Cch William, S Simmrat, A M Suhaeb
Infection of the hip after implant fixation is an uncommon yet devastating complication that results in poor long-term outcome. The gold standard treatment for chronic infection after hip arthroplasty is a two-stage protocol: eradication of infection, follow by re-implantation arthroplasty. The use of interim antibiotic-laden cement spacer has become a popular procedure to maintain hip joint function and provide antibiotic elution simultaneously before re-implantation. However, antibiotic cement spacer is mechanically weak and breaks if overloaded...
July 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29019757/pediatric-ovarian-torsion-spectrum-of-imaging-findings
#7
Akosua Sintim-Damoa, Anand Shyamcharan Majmudar, Harris L Cohen, Louis Swig Parvey
The accurate diagnosis of ovarian torsion is imperative, as loss of the ovary can have long-term consequences in terms of fertility. However, a nonspecific clinical presentation in conjunction with a highly variable imaging appearance makes the diagnosis of ovarian torsion challenging. This is complicated even further in the pediatric population, as these patients cannot always articulate their symptoms or provide an adequate medical history. Therefore, imaging has a critical role in the diagnosis of ovarian torsion in pediatric patients...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29019122/2d-dige-and-fluorescence-image-analysis
#8
Elisa Robotti, Emilio Marengo
2D-DIGE is still a very widespread technique in proteomics for the identification of panels of biomarkers, allowing to tackle with some important drawback of classical two-dimensional gel-electrophoresis. However, once 2D-gels are obtained, they must undergo a quite articulated multistep image analysis procedure before the final differential analysis via statistical mono- and multivariate methods. Here, the main steps of image analysis software are described and the most recent procedures reported in the literature are briefly presented...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29018654/double-crush-of-l5-spinal-nerve-root-due-to-l4-5-lateral-recess-stenosis-and-bony-spur-formation-of-lumbosacral-transitional-vertebra-pseudoarticulation-a-case-report-and-review
#9
Motoyuki Iwasaki, Masahiko Akiyama, Izumi Koyanagi, Yoshimasa Niiya, Tatsuo Ihara, Kiyohiro Houkin
We present a case of double-crushed L5 nerve root symptoms caused by inside and outside of the spinal canal with spur formation of the lumbosacral transitional vertebra (LSTV). A 78-year-old man presented with 7-year history of moderate paresis of his toe and left leg pain when walking. Magnetic resonance imaging (MRI) revealed spinal stenosis at the L3/4 and 4/5 spinal levels and he underwent wide fenestration of both levels. Leg pain disappeared and 6-min walk distance (6MWD) improved after surgery, however, the numbness in his toes increased and 6MWD decreased 9 months after surgery...
October 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/29018379/word-order-and-voice-influence-the-timing-of-verb-planning-in-german-sentence-production
#10
Sebastian Sauppe
Theories of incremental sentence production make different assumptions about when speakers encode information about described events and when verbs are selected, accordingly. An eye tracking experiment on German testing the predictions from linear and hierarchical incrementality about the timing of event encoding and verb planning is reported. In the experiment, participants described depictions of two-participant events with sentences that differed in voice and word order. Verb-medial active sentences and actives and passives with sentence-final verbs were compared...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29018216/structural-and-mechanistic-characterization-of-an-archaeal-like-chaperonin-from-a-thermophilic-bacterium
#11
Young Jun An, Sara E Rowland, Jung-Hyun Na, Dario Spigolon, Seung Kon Hong, Yeo Joon Yoon, Jung-Hyun Lee, Frank T Robb, Sun-Shin Cha
The chaperonins (CPNs) are megadalton sized hollow complexes with two cavities that open and close to encapsulate non-native proteins. CPNs are assigned to two sequence-related groups that have distinct allosteric mechanisms. In Group I CPNs a detachable co-chaperone, GroES, closes the chambers whereas in Group II a built-in lid closes the chambers. Group I CPNs have a bacterial ancestry, whereas Group II CPNs are archaeal in origin. Here we describe open and closed crystal structures representing a new phylogenetic branch of CPNs...
October 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/29017508/on-neuromechanical-approaches-for-the-study-of-biological-and-robotic-grasp-and-manipulation
#12
REVIEW
Francisco J Valero-Cuevas, Marco Santello
Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs. engineering mechanisms are, by definition, dramatically different and can even be antithetical. Even our approach to each is diametrically opposite: inductive science for the study of biological systems vs. engineering synthesis for the design and construction of robotic systems. The past 20 years have seen several conceptual advances in both fields and the quest to unify them...
October 9, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29016171/the-psychology-of-neurofeedback-clinical-intervention-even-if-applied-placebo
#13
Robert T Thibault, Amir Raz
Advocates of neurofeedback make bold claims concerning brain regulation, treatment of disorders, and mental health. Decades of research and thousands of peer-reviewed publications support neurofeedback using electroencephalography (EEG-nf); yet, few experiments isolate the act of receiving feedback from a specific brain signal as a necessary precursor to obtain the purported benefits. Moreover, while psychosocial parameters including participant motivation and expectation, rather than neurobiological substrates, seem to fuel clinical improvement across a wide range of disorders, for-profit clinics continue to sprout across North America and Europe...
October 2017: American Psychologist
https://www.readbyqxmd.com/read/28994616/assessing-speech-perception-in-swedish-school-aged-children-preliminary-data-on-the-listen-say-test
#14
Cecilia Nakeva von Mentzer, Martina Sundström, Karin Enqvist, Mathias Hällgren
To meet the need for a linguistic speech perception test in Swedish, the 'Listen-Say test' was developed. Minimal word pairs were used as speech material to assess seven phonetic contrasts in two auditory backgrounds. In the present study, children's speech discrimination skills in quiet and in four-talker (4T) speech background were examined. Associations with lexical-access skills and academic achievement were explored. The study included 27 school children 7-9 years of age. Overall, the children discriminated phonetic contrasts well in both conditions (quiet: Mdn 95%; 4T speech; Mdn 91% correct)...
October 10, 2017: Logopedics, Phoniatrics, Vocology
https://www.readbyqxmd.com/read/28993231/decoding-spoken-phonemes-from-sensorimotor-cortex-with-high-density-ecog-grids
#15
REVIEW
N F Ramsey, E Salari, E J Aarnoutse, M J Vansteensel, M B Bleichner, Z V Freudenburg
For people who cannot communicate due to severe paralysis or involuntary movements, technology that decodes intended speech from the brain may offer an alternative means of communication. If decoding proves to be feasible, intracranial Brain-Computer Interface systems can be developed which are designed to translate decoded speech into computer generated speech or to instructions for controlling assistive devices. Recent advances suggest that such decoding may be feasible from sensorimotor cortex, but it is not clear how this challenge can be approached best...
October 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28991584/the-role-of-wrist-arthroscopy-in-kienbock-disease
#16
REVIEW
Simon B M MacLean, Karim Kantar, Gregory I Bain, David M Lichtman
Kienbock disease (KD) is a disease of uncertain etiology, leading to chondral and osseous change in the lunate and wrist. Traditionally, Lichtman's classification of KD, based on radiographic appearances, has been used to direct treatment. Diagnostic wrist arthroscopy allows direct assessment of the lunate and surrounding articulations. Wrist arthroscopy can also serve as a therapeutic tool for performing debridement, resection, or arthrodesis procedures. The new Lichtman-Bain algorithm takes into consideration the status of the lunate, the effect on the wrist, and surgical and patient factors to guide management...
November 2017: Hand Clinics
https://www.readbyqxmd.com/read/28990319/a-qualitative-study-on-community-pharmacists-decision-making-process-when-making-a-diagnosis
#17
Vassiliki Sinopoulou, Paul Summerfield, Paul Rutter
RATIONALE, AIMS, AND OBJECTIVES: Self-care policies are increasingly directing patients to seek advice from community pharmacists. This means pharmacists need to have sound diagnostic decision-making skills to enable them to recognise a variety of conditions. The aim of this study was to investigate the process by which pharmacists manage patient signs and symptoms and to explore their use of decision-making for diagnostic purposes. METHODS: Data were collected through semi-structured, face-to-face interviews with community pharmacists working in England, between August 2013 and November 2014...
October 8, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28990309/making-sense-of-frailty-an-ethnographic-study-of-the-experience-of-older-people-living-with-complex-health-problems
#18
Julie Kathryn Skilbeck, Antony Arthur, Jane Seymour
AIM: To explore how older people with complex health problems experience frailty in their daily lives. BACKGROUND: A better understanding of the personal experience of frailty in the context of fluctuating ill-health has the potential to contribute to the development of personalised approaches to care planning and delivery. DESIGN: An ethnographic study of older people, living at home, receiving support from a community matron service in a large city in the North of England...
October 9, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/28987044/-application-of-brain-boy-universal-professional-in-preliminary-assessment-of-auditory-processing-disorder
#19
Joanna Rutkowska, Anna Łobaczuk-Sitnik, Bożena Kosztyła-Hojna
Increasing numbers of hearing pathology is auditory processing disorders. Auditory Processing Disorders (APD) are defined as difficulty in using auditory information to communicate and learn in the presence of normal peripheral hearing. It may be recognized as a problem with understanding of speech in noise and perception disorder of distorted speech. APD may accompany to articulation disorders, language problems and difficulties in reading and writing. The diagnosis of auditory processing disorders causes many difficulties primarily due to the lack of common testing procedures, precise criteria for qualification to the group of norm and pathology...
September 29, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28986663/dislocations-after-use-of-dual-mobility-cups-in-cementless-primary-total-hip-arthroplasty-prospective-multicentre-series
#20
Ji-Hyo Hwang, Sang-Min Kim, Kwang-Jun Oh, Yeesuk Kim
BACKGROUND: The purpose of this study was to investigate the incidence of dislocation and specific complications of the dual-mobility cup. METHODS: The arthroplasties involved 167 hips in 165 patients; 51 hips (30.5%) were in men and 116 (69.4%) were in women. The active articulation E1® dual-mobility cup (Biomet, Warsaw, IN, USA) was used, and the surgical approach was posterolateral in 120 hips and anterolateral in 47 hips. RESULTS: Four (2...
October 7, 2017: International Orthopaedics
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