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Small for gestational age

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https://www.readbyqxmd.com/read/28338874/does-fetal-growth-restriction-cause-later-obesity-pitfalls-in-analyzing-causal-mediators-as-confounders
#1
Michael S Kramer, Xun Zhang, Mourad Dahhou, Seungmi Yang, Richard M Martin, Emily Oken, Robert W Platt
Recent studies finding that small-for-gestational-age (SGA) birth is associated with increased adiposity in childhood and adulthood have been based on analyses "adjusting" for height, weight, or body mass index (BMI; weight (kg)/height (m)2) measured concurrently with the adiposity measurement. To assess the potential for bias due to overadjustment for a causal mediator, we compared 2 approaches to analyzing the association between SGA birth and adiposity outcomes (skinfold thicknesses and bioelectrical impedance measurement of body fat) at age 11...
March 3, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28337896/maternal-obesity-and-perinatal-oxidative-stress-the-strength-of-the-association
#2
S Negro, T Boutsikou, D D Briana, M L Tataranno, M Longini, F Proietti, F Bazzini, C Dani, A Malamitsi-Puchner, G Buonocore, S Perrone
Maternal obesity is a chronic inflammatory state, which has been shown to induce increased levels of free fatty acids, reactive oxygen species and inflammatory cells. Recent evidence reveals increased levels of lipid peroxidation products in the plasma of obese women during pregnancy. The aim of this study was to test the hypothesis that maternal overweight or obesity is associated with increased oxidative stress (OS) in offspring. Two hundred and forty-five pregnant women and their newborns were prospectively enrolled...
January 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28337595/first-trimester-ttr-rbp4-roh-complex-and-angiogenic-factors-in-the-prediction-of-small-for-gestational-age-infant-s-outcome
#3
Arrigo Fruscalzo, Julia Frommer, Ambrogio P Londero, Andrea Henze, Florian J Schweigert, Jerzy-Roch Nofer, Johannes Steinhard, Walter Klockenbusch, Ralf Schmitz, Jens Raila
PURPOSE: To study the role of the TTR-RBP4-ROH complex components (transthyretin, serum retinol binding protein, retinol) and of angiogenic factors PlGF (placental growth factor) and sFlt-1 (soluble fms-like tyrosine kinase-1) in pregnancies complicated by small for gestational age infants (SGA). METHODS: Case control study conducted on maternal serum collected between 11 + 0 to 13 + 6 weeks of gestation. TTR, RBP4, ROH, PlGF and sFlt-1 were measured in SGA patients (birth weight <10%) who delivered at term (n = 37) and before 37 weeks of gestation (n = 17) and in a matched control group with uneventful pregnancies (n = 37)...
March 23, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28334337/birth-outcomes-among-adolescent-and-young-adult-cancer-survivors
#4
Chelsea Anderson, Stephanie M Engel, Jennifer E Mersereau, Kristin Z Black, William A Wood, Carey K Anders, Hazel B Nichols
Importance: Cancer diagnosis and treatment may adversely affect reproductive outcomes among female cancer survivors. Objective: To compare the birth outcomes of adolescent and young adult cancer survivors (AYA [diagnosed at ages 15-39 years]) with those of women without a cancer diagnosis. Design, Setting, and Participants: The North Carolina Central Cancer Registry (CCR) was used to identify female AYA cancer survivors diagnosed from January 2000 to December 2013; CCR records were linked to statewide birth certificate files from January 2000 to December 2014 to identify postdiagnosis live births to AYA survivors (n = 2598)...
March 23, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28332212/accuracy-of-sonographic-fetal-weight-estimation-prior-to-delivery-in-a-chinese-han-population
#5
Yao Shen, WeiXiu Zhao, JianHua Lin, FangSun Liu
OBJECTIVE: To compare the sonographic-estimated fetal weights (EFW) calculated with the Hadlock formula and with the Woo formula in a group of Chinese pregnant women. METHODS: We prospectively recruited term pregnancies for sonographic biometric examination. EFWs were calculated according to two formulas and compared with the corresponding birth weight (BW). We also assessed the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of EFW for the diagnosis of small-for-gestational age (SGA) and large-for-gestational age (LGA) neonates...
March 23, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28332106/inadequate-gestational-weight-gain-predicts-adverse-pregnancy-outcomes-in-mothers-with-inflammatory-bowel-disease-results-from-a-prospective-us-pregnancy-cohort
#6
May-Bente Bengtson, Christopher F Martin, Geir Aamodt, Morten H Vatn, Uma Mahadevan
BACKGROUND: Malnutrition and weight loss are common features of patients with inflammatory bowel disease (IBD). AIM: To explore the impact of inadequate gestational weight gain (GWG) on adverse outcomes among IBD mothers in the prospective US pregnancy in Inflammatory Bowel Disease and Neonatal Outcomes (PIANO) cohort. METHODS: The PIANO cohort comprises 559 and 363 pregnant mothers with Crohn's disease (CD) and ulcerative colitis (UC), respectively, enrolled between 2006 and 2014...
March 22, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28331865/growth-hormone-utilization-review-in-a-pediatric-primary-care-setting
#7
Fatemeh Sayarifard, Fereshteh Bakhshi Imcheh, Shirinsadat Badri, Toktam Faghihi, Mostafa Qorbani, Mania Radfar
OBJECTIVE: One of the main problems facing public health providers and administrators in many countries is ensuring the rational use of high-cost drugs. In this regard, on-going process of medication use evaluation can be considered as a useful tool. In this study, we evaluated certain usage aspects of a highly-cost medication, that is, recombinant growth hormone (GH). METHODS: This cross-sectional study conducted from August 2012 to August 2014. Children receiving GH ± gonadotropin releasing hormone (GnRH) analogs were included in the study...
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28329257/lessons-learned-at-the-epicenter-of-brazil-s-congenital-zika-epidemic-evidence-from-87-confirmed-cases
#8
Jucille do Amaral Meneses, Ana Catarina Ishigami, Luisa Medeiros de Mello, Luciano Lira de Albuquerque, Carlos Alexandre Antunes de Brito, Marli Tenório Cordeiro, Lindomar José Pena
Congenital Zika virus infection has stimulated great international concern. A prospective case series of 87 infants with laboratory-confirmed congenital Zika syndrome (CZS) at the epicenter of the Brazilian Zika epidemic in Pernambuco state is presented. Mothers were interviewed for symptoms of possible Zika virus (ZIKV) infection during pregnancy and fetal ultrasounds were obtained. Infant cerebrospinal fluid (CSF) samples were tested for ZIKV specific antibodies and sera were screened for other congenital infections...
February 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28326518/chorionic-thickness-and-plgf-concentrations-as-early-predictors-of-small-for-gestational-age-birth-weight-in-a-low-risk-population
#9
Anna Gąsiorowska, Marek Pietryga, Agnieszka Zawiejska, Piotr Dydowicz, Katarzyna Ziółkowska, Hubert Wolski, Jacek Brązert
OBJECTIVES: SGA is associated with higher incidence of postnatal complications, including suboptimal neurodevelopment and increased cardiovascular risk. Screening for SGA, carried out at 11-13 (+ 6d) gestational weeks enables to reduce or completely eliminate the above mentioned complications. The aim of this study was to assess the correlation between chorionic thickness, concentration of PIGF protein and foetal birth weight in a single low-risk pregnancy. MATERIAL AND METHODS: The study included 76 patients at 11-13 (+ 6d) gestational weeks, monitored throughout preg-nancy...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28325171/pregnancy-and-neonatal-outcomes-among-a-cohort-of-hiv-infected-women-in-a-large-italian-teaching-hospital-a-30-year-retrospective-study
#10
S Grignolo, R Agnello, D Gerbaldo, C Gotta, C Alicino, F Del Puente, L Taramasso, B Bruzzone, C Gustavino, S Trasino, A DE Maria, G Icardi, C Viscoli, A DI Biagio
The primary study objective was to investigate three decades from 1985 to 2014 of changes in pregnancies among HIV-infected women. The secondary objective was to assess risk factors associated with preterm delivery and severe small-for-gestational-age (SGA) infants in HIV-infected women. A retrospective review of deliveries among pregnant HIV-infected women at the University of Genoa and IRCCS San Martino-IST in Genoa between 1985 and 2014 was performed. Univariate and multivariable analyses were used to study the variables associated with neonatal outcomes...
March 22, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28325085/risk-of-recurrence-of-small-for-gestational-age-foetus-after-first-pregnancy
#11
Sebastián Manzanares, M Teresa Maroto-Martín, Mariña Naveiro, Mar Sánchez-Gila, Setefilla López-Criado, Alberto Puertas
The aim of this study was to assess the incidence of and to analyse factors related to the recurrence of small-for-gestational-age (SGA) neonates in the second pregnancy. A prospective observational study was conducted at a tertiary university hospital in Granada, Spain. A total of 7896 women who delivered their first and second singleton pregnancies at the hospital from 2003-2013 were included and evaluated all birth weights. Women whose first pregnancy was complicated by a SGA birth had a fivefold increased risk of recurrence (23...
March 21, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28324040/cord-blood-adipocyte-fatty-acid-binding-protein-levels-correlate-with-gestational-age-and-birth-weight-in-neonates
#12
Kyoung Eun Joung, Sule Umit Cataltepe, Zoe Michael, Helen Christou, Christos S Mantzoros
Context: Infants born small for gestational age (SGA) have increased risk for obesity and metabolic syndrome in future life, but the underlying mechanisms are not fully elucidated. Adipocyte fatty acid binding protein, is an adipokine that has been implicated in modulation of insulin sensitivity and lipid metabolism. Higher plasma AFABP levels are associated with increased risk of metabolic syndrome and cardiovascular morbidity in adults. Alterations in AFABP levels during fetal growth have not been characterized...
January 31, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28322644/meta-analyses-of-predictors-of-health-practices-in-pregnant-women
#13
Barbara L Cannella, Adela Yarcheski, Noreen E Mahon
The aims of this study were to identify predictors of health practices of pregnant women in the literature reviewed, to use meta-analysis to ascertain the mean effect size (ES) across studies between each predictor and health practices, and to examine four moderators on each predictor-health practices relationship. Using preferred reporting items for systematic reviews and meta-analyses guidelines for the literature assessed, 32 published studies or doctoral dissertations completed between 1992 and 2015 met the inclusion criteria...
December 1, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28321896/does-tea-consumption-during-early-pregnancy-have-an-adverse-effect-on-birth-outcomes
#14
Jin-Hua Lu, Jian-Rong He, Song-Ying Shen, Xue-Ling Wei, Nian-Nian Chen, Ming-Yang Yuan, Lan Qiu, Wei-Dong Li, Qiao-Zhu Chen, Cui-Yue Hu, Hui-Min Xia, Suzanne Bartington, Kar Keung Cheng, Kin Bong Hubert Lam, Xiu Qiu
BACKGROUND: Tea, a common beverage, has been suggested to exhibit a number of health benefits. However, one of its active ingredients, caffeine, has been associated with preterm birth and low birthweight. We investigated whether tea consumption during early pregnancy is associated with an increased risk of preterm birth and abnormal fetal growth. METHODS: A total of 8775 pregnant women were included from the Born in Guangzhou Cohort Study. Tea consumption (type, frequency, and strength) during their first trimester and social and demographic factors were obtained by way of questionnaires administered during pregnancy...
March 21, 2017: Birth
https://www.readbyqxmd.com/read/28320796/effect-of-alcohol-consumption-and-psychosocial-stressors-on-preterm-and-small-for-gestational-age-births-in-hiv-infected-women-in-south-africa-a-cohort-study
#15
Ayesha Sania, Kirsty Brittain, Tamsin K Phillips, Allison Zerbe, Agnes Ronan, Landon Myer, Elaine J Abrams
OBJECTIVES: Psychosocial stressors such as depression and stress, intimate partner violence (IPV) and alcohol use have been linked to preterm and small-for-gestational-age (SGA) births in general populations. The prevalence of psychosocial stressors and alcohol abuse is high in many HIV-infected (HIV+) populations. Our objective was to evaluate the effects of psychosocial stressors and alcohol abuse on birth outcomes in HIV-infected women. METHODS: Antenatal depression and non-specific psychological distress, periconception IPV and alcohol consumption were measured during the second trimester among HIV+ women initiating antiretroviral treatment with efavirenz + emtricitibine + tenofovir in Cape Town, South Africa...
March 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28320392/prenatal-and-post-natal-cost-of-small-for-gestational-age-infants-a-national-study
#16
Alicia Marzouk, Antoine Filipovic-Pierucci, Olivier Baud, Vassilis Tsatsaris, Anne Ego, Marie-Aline Charles, François Goffinet, Danièle Evain-Brion, Isabelle Durand-Zaleski
BACKGROUND: Small for gestational age (SGA) infants are at increased risk for preterm birth morbidities as well as a range of adverse perinatal outcomes that result in part from associated premature birth. We sought to evaluate the costs of SGA versus appropriate for gestational age (AGA) infants in France from pregnancy through the first year of life and separate the contributions of prematurity from the contribution of foetal growth on costs. METHODS: This is a cross-sectional population-based study using national hospital discharge data from French public and private hospitals...
March 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28319949/the-impact-of-kidney-development-on-the-life-course-a-consensus-document-for-action
#17
(no author information available yet)
Hypertension and chronic kidney disease (CKD) have a significant impact on global morbidity and mortality. The Low Birth Weight and Nephron Number Working Group has prepared a consensus document aimed to address the relatively neglected issue for the developmental programming of hypertension and CKD. It emerged from a workshop held on April 2, 2016, including eminent internationally recognized experts in the field of obstetrics, neonatology, and nephrology. Through multidisciplinary engagement, the goal of the workshop was to highlight the association between fetal and childhood development and an increased risk of adult diseases, focusing on hypertension and CKD, and to suggest possible practical solutions for the future...
March 21, 2017: Nephron
https://www.readbyqxmd.com/read/28319175/preeclampsia-in-kidney-transplanted-women-outcomes-and-a-simple-prognostic-risk-score-system
#18
Guri Baardstu Majak, Anna Varberg Reisæter, Manuela Zucknick, Bjørg Lorentzen, Siri Vangen, Tore Henriksen, Trond Melbye Michelsen
Women pregnant following kidney transplantation are at high risk of preeclampsia. Identifying the effects of preeclampsia on pregnancy outcome and allograft function in kidney transplanted women, and predicting which women will require more targeted follow-up and possible therapeutic intervention, could improve both maternal and neonatal outcome. In this retrospective cohort study of all pregnancies following kidney transplantation in Norway between 1969 and 2013, we used medical records to identify clinical characteristics predictive of preeclampsia...
2017: PloS One
https://www.readbyqxmd.com/read/28318530/oxygen-targeting-in-infants-born-extremely-preterm-who-are-small-for-gestational-age-a-need-for-heightened-vigilance
#19
EDITORIAL
Barbara Schmidt, Robin K Whyte, Robin S Roberts
No abstract text is available yet for this article.
March 15, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28317131/association-of-shorter-height-with-increased-risk-of-ischaemic-placental-disease
#20
Kohei Ogawa, Naho Morisaki, Shigeru Saito, Shoji Sato, Takeo Fujiwara, Haruhiko Sago
BACKGROUND: Although adult height is inversely related with the risk of chronic disease, the association between maternal height and ischaemic placental disease remains unclear. METHODS: We used the national, multicentre Japan Society of Obstetrics and Gynecology perinatal database to assess the risk of preeclampsia, placental abruption, and small for gestational age (SGA) births (birthweight < 10th percentile), which together constitute the syndrome 'ischaemic placental disease', in relation to self-reported height in 218 412 women with no underlying diseases before pregnancy, who delivered singletons in 2005-11...
March 20, 2017: Paediatric and Perinatal Epidemiology
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