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Hyperoxygenation & wound infection

Mario Schietroma, Beatrice Pessia, Sara Colozzi, Francesco Carlei, Ina Shehaj, Gianfranco Amicucci
UNLABELLED: Propose: The clinical role of hyperoxiato prevent postoperative surgical site infection (SSI) remains uncertain since randomized controlled trials on this topic have reported different results. One of the principal reasons for such mixed results can be that previous trials have entered a heterogeneous population of patients and set of procedures. The aim of our study was to assess the influence of hyperoxygenation on SSI usingan homogeneous study population. METHODS: We studied, in a prospective randomized study, extended on a time interval January 2009 to May 2015, 85 patients who underwent open intraperitoneal anastomosis for acute sigmoid diverticulitis...
May 2016: Chirurgia
Mario Schietroma, Emanuela M Cecilia, Federico Sista, Francesco Carlei, Beatrice Pessia, Gianfranco Amicucci
BACKGROUND: Perioperative supplemental oxygen has been proposed to decrease the incidence of surgical site infection (SSI) in colorectal surgery with controversial results. We have assessed the influence of hyperoxygenation on SSI by using the most homogeneous study population. METHODS: We studied, in a prospective randomized study, 81 patients, who underwent elective open infraperitoneal anastomosis for rectal cancer. Patients were assigned randomly to an oxygen/air mixture with a fraction of inspired oxygen (FiO2) of 30% (n = 41) or 80% (n = 40)...
November 2014: American Journal of Surgery
Montse Mallol, Antoni Sabaté, Esther Kreisler, Antonia Dalmau, Imma Camprubi, Loris Trenti, Sebastiano Biondo
INTRODUCTION: Surgical wound infection in colorectal surgery has incidence rate of up to 26%. Peri-operative factors and those of the patients themselves play a part in these infections. The correct administration of the antibiotic, a normal temperature, and hyperoxygenation are a commonly applied triad. The primary aim of the study was to evaluate the incidence of surgical wound infection in patients subjective to colorectal surgery where a surgical infection prevention protocol was applied...
June 2012: Cirugía Española
Amitai Bickel, Michael Gurevits, Ronny Vamos, Simon Ivry, Arieh Eitan
OBJECTIVE: To assess the influence of hyperoxygenation on surgical site infection by using the most homogeneous study population. DESIGN: A randomized, prospective, controlled trial. SETTING: Department of surgery in a government hospital. PATIENTS: A total of 210 patients who underwent open surgery for acute appendicitis. In the study group, patients received 80% oxygen during anesthesia, followed by high-flow oxygen for 2 hours in the recovery room...
April 2011: Archives of Surgery
Katharine W Markell, Ben M Hunt, Paul D Charron, Rodney J Kratz, Jeffrey Nelson, John T Isler, Scott R Steele, Richard P Billingham
BACKGROUND: Postoperative wound infections are a widespread and costly problem, especially in colorectal surgery. Despite their prevalence, there are few data regarding appropriate management and prevention strategies. MATERIALS AND METHODS: In order to assess current attitudes and practices about this subject, and as a guide to designing a randomized trial to gather evidence in order to support data-driven protocol development, an e-mail survey was sent to the membership of the American Society of Colorectal Surgeons to assess current attitudes and practices pertaining to prevention and management of wound infections...
July 2010: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Robert J Goldman
This article is a systematic review evaluating published clinical evidence of the efficacy of hyperbaric oxygen therapy (HBOT) for wound healing and limb salvage. The data source is the Ovid/Medline database for key word "Hyperbaric Oxygenation" with search limits (human studies, 1978-2008). Results were combined by Boolean AND with 1 of the 3 following searches: (a) wound healing (10 permutations); (b) compromised flap or graft (3); and (c) osteomyelitis (1). The author evaluated 620 citations, of which 64 reported original observational studies and randomized controlled trials (RCTs) on HBOT and healing outcomes...
May 2009: PM & R: the Journal of Injury, Function, and Rehabilitation
A Kibadi Kapay, J B Mputu-Yamba, T Muyembe, G Bonga, A N'Siala
The Buruli ulcer (BU) rages in a lot of tropical and subtropical countries. In Democratic Republic of Congo, some BU cases were reported between the 50s and 70s. This disease offers resistance to the usual chemotherapy. The only alternative for the treatment remains the surgical one (trimming, wound dressing, graft). The overarching aim of this study, conducted in the province of Lower Congo, is to put forward a surgical therapeutic approach adapted to the precarious conditions met on the ground in our rural areas...
April 2005: Bulletin de la Société de Pathologie Exotique
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