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https://www.readbyqxmd.com/read/29352928/thermo-sensitive-injectable-glycol-chitosan-based-hydrogel-for-treatment-of-degenerative-disc-disease
#1
Zhengzheng Li, Hyeeun Shim, Myeong Ok Cho, Ik Sung Cho, Jin Hyun Lee, Sun-Woong Kang, Bosun Kwon, Kang Moo Huh
The use of injectable hydrogel formulations have been suggested as a promising strategy for the treatment of degenerative disc disease to both restore the biomechanical function and reduce low back pain. In this work, a new thermo-sensitive injectable hydrogels with tunable thermo-sensitivity and enhanced stability were developed with N-hexanoylation of glycol chitosan (GC) for treatment of degenerative disc disease, and their physico-chemical and biological properties were evaluated. The sol-gel transition temperature of the hydrogels was controlled in a range of 23-56 °С, depending on the degree of hexanoylation and the polymer concentration...
March 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352359/unilateral-lichtenstein-tension-free-mesh-hernia-repair-and-testicular-perfusion-a-prospective-control-study
#2
J Aguilar-García, H A Cano-González, M A Martínez-Jiménez, F de la Rosa-Zapata, M Sánchez-Aguilar
PURPOSE: Compare testicular perfusion between the herniated and the healthy side pre- and post-surgery. MATERIALS AND METHODS: Our study was done on patients with unilateral inguinal hernia. A Doppler ultrasound study was performed in the healthy and herniated side before surgery and 3 months after it. RESULTS: 31 patients were included, 74.2% on the right and 25.8% on the left side. When comparing the pre-surgical values of testicular resistance index from the healthy side with those on the herniated side, there was a significant difference at the spermatic cord levels (0...
January 19, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29350650/clinical-and-instrumental-assessment-of-herniated-discs-after-nucleoplasty-a-preliminary-study
#3
Alessandro Liguori, Federica Galli, Martina Gurgitano, Anna Borelli, Marco Pandolfi, Ferdinando Caranci, Alberto M Magenta Biasina, Giovanni G M Pompili, Claudia L Piccolo, Vittorio Miele, Carlo Masciocchi, Giampaolo Carrafiello
BACKGROUND AND AIM: The therapy for low back pain boasts different approaches; one of these is nucleoplasty. We wanted to assess the effectiveness of nucleoplasty both by clinical response both by MR imaging evaluation, including even extrusions larger than one third of the spinal canal. METHODS: Fifty-seven patients were treated with nucleoplasty in our hospital, 11 of these patients accepted both clinical and MRI evaluation after six months from treatment. The clinical evaluation was performed with Visual Analogue Scale (VAS) of pain, scored before and after the procedure...
January 19, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350292/disc-herniation-occult-on-preoperative-imaging-but-visualized-microsurgically-as-the-cause-of-idiopathic-thoracic-spinal-cord-herniation
#4
Christian T Ulrich, Christian Fung, Eike Piechowiak, Jan Gralla, Andreas Raabe, Jürgen Beck
Idiopathic spinal cord herniation (ISCH) through an anterior dural defect is rare and the cause is uncertain. Recently, through interpreting imaging studies, disc herniation was proposed to be a major cause for ISCH. We describe the case of a 50-year-old woman with progressive myelopathy who was diagnosed with a thoracic spinal cord herniation. Microsurgical exploration revealed an anterior vertical dural defect and a small concomitant disc herniation, occult on the preoperative imaging, which caused the dural defect and led to ISCH...
January 19, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29350001/-analysis-of-complications-of-percutaneous-endoscopic-lumbar-discectomy
#5
Ke-Lun Huang, Hong-Lin Teng, Min-Yu Zhu, Jing Wang, Chi Li, Yu Wang
OBJECTIVE: To analyze the complications of lumbar intervertebral disc herniation treated with percutaneous endoscopic lumbar discectomy(PELD), and discuss how to avoid these complications. METHODS: The data of 132 patients with lumbar intervertebral disc herniation underwent PELD from October 2013 and June 2015 were retrospectively analyzed, including 85 males and 47 females with an average age of 42.9 years old. There were 6 cases of L₃,₄, 68 of L₄,₅ and 58 of L₅S₁...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349999/-percutaneous-endoscopic-lumbar-discectomy-combined-with-epidural-injection-for-prolapsed-lumbar-disc-herniation
#6
Hai-Hao Wu, Tao Tang, Qing-Jiang Pang, Yun Wang, Zong-Kai Zhang
OBJECTIVE: To assess the effect of percutaneous endoscopic lumbar discectomy (PELD) combined with epidural injection for prolapsed lumbar disc herniation(PLDH). METHODS: In this prospective randomized controlled study, the clinical data of 126 patients who had undergone a PELD because of a single-level PLDH from March 2014 to June 2015 were analyzed. There were 67 males and 59 females, ranging in age from 17 to 75 years old with an average of(41.0±13.5) years old, 9 cases were L₃,₄, 76 cases were L₄,₅ and 41 cases were L₅S₁...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349997/-surgical-outcome-of-percutaneous-endoscopic-technique-for-highly-migrated-disc-herniation-via-three-different-approaches
#7
Yi Jiang, Ru-Jun Zuo, Lei Wu, Cheng Huang, Yan Shi, Hua-Wei Song, Yi-Wei Wang, Bin Li
OBJECTIVE: To analyze the clinical effects of percutaneous endoscopic technique via three different approaches for highly migrated lumbar disc herniation. METHODS: The clinical data of 68 patients underwent percutaneous endoscopic technique from June 2011 to June 2014 were retrospectively analyzed. There were 43 males and 25 females, aged from 11 to 77 years old with an average of (42.29±15.92) years. The patients were divided into three groups according to different operative approaches, of them, 45 cases were by transforaminal approach (group A), 15 cases by translaminar approach (group B), and 8 cases by transpedicular approach (group C)...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349965/-clinical-characteristics-analysis-of-lumbar-disc-herniation-with-symptom-aggravated-caused-by-spinal-manipulative-therapy
#8
Feng Zhao, Jun-Peng Pei, Pan Diao, Zhi-Li Meng, Yuan Sun, Sheng-Li Huang
OBJECTIVE: To discuss the characteristics of lumbar disc herniation (LDH) with symptom aggravated caused by spinal manipulative therapy (SMT). METHODS: Detailed clinical profiles of a total number of 10 LDH patients with symptoms aggravated after SMT were reviewed including 5 males and 5 females with age from 46 to 68 years old, 7 patients of them were more than 50 years old. The clinical data of 10 patients were analyzed involving age, gender, clinical symptoms, signs, imaging findings, surgical treatment and prognosis...
March 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349958/-biomechanical-analysis-of-the-correlation-between-sacral-tilt-displacement-and-l%C3%A2-s%C3%A2-disc-degeneration
#9
Ning-Ning Shi, Guo-Quan Shen, Shui-Yong He, Ru-Bao Gu, Shui-Yong He
OBJECTIVE: To biomechanical analysis of the correlation between sacral tilt displacement and L₅-S₁ disc degeneration. METHODS: From July 2011 to July 2013, 81 patients with lumbar disc herniation and sacroiliac joint disorder including 45 males and 36 females with an average age of (45.39±1.30) years ranging from 18 to 65 years old were selected. The course of the disease ranged from 1 to 144 months with an average of (12.64±2.19) months. All patients were taken lumbar spine lateral X-ray films, the lumbar curvature angle, L₄-L₅ or L₅-S₁ intervertebral gap distance between points, and the lumbosacral angle was measured and correlated analyzed...
March 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29346830/feasibility-of-navigable-percutaneous-disk-decompressor-l-disq-c-for-cervical-disk-herniation
#10
Youngki Hong, Seunghan Yoo, Nack Hwan Kim, Yushin Kim, Sangho Sohn, Sung-Young Yoon, Sangheon Lee
OBJECTIVE:  To assess the procedural efficacy and safety of a Navigable Percutaneous Disk Decompressor (L'DISQ-C) for cervical disk herniation. METHODS:  We performed intradiskal decompression on cervical spine specimens from five human cadavers using the L'DISQ-C under C-arm fluoroscopic guidance. We evaluated our success for positioning the navigable wand tip into the target region and recorded temperature variation at various distances from the wand tip in the cervical nucleus pulposus...
January 18, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29343753/procalcitonin-as-a-biomarker-for-malignant-cerebral-edema-in-massive-cerebral-infarction
#11
Yan Zhang, Gang Liu, Yuan Wang, Yingying Su, Rehana K Leak, Guodong Cao
The objective of this study is to explore whether procalcitonin (PCT) can serve as an early biomarker of malignant cerebral edema in patients with massive cerebral infarction (MCI). Ninety-three patients with acute MCI were divided into death or survival groups based on whether they died or survived within 1 week of cerebral herniation. Differences in laboratory parameters between these two groups were analyzed by univariate analysis, followed by multivariate logistic regression analyses if the influencing factors were significantly different...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343035/-comparison-of-percutaneous-endoscopic-lumbar-discectomy-versus-transforaminal-lumbar-interbody-fusion-in-treating-upper-lumbar-disc-herniation
#12
Y W Li, H J Wang, Y S Wang, W Cui, P Zhou, C Li
Objective: To compare the efficacy of percutaneous endoscopic transforaminal discectomy (PTED) and transforaminal lumbar interbody fusion (TLIF) in the treatment of high lumbar disc herniation. Methods: The clinical data of patients with high lumbar disc herniation from February 2010 to February 2015 were retrospective analyzed. According to the inclusion criteria, a total of 63 cases were enrolled, including PTED group 33 cases, TLIF group 30 cases. The improvement of the two groups before and after surgery was assessed by visual analogue scale (VAS) and Oswestry dysfunction index (ODI)...
January 9, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29342445/case-report-of-an-uncommon-case-of-drain-site-hernia-after-colorectal-surgery
#13
M Manigrasso, P Anoldo, F Milone, G D De Palma, M Milone
BACKGROUND: trocar site herniation is a rare but potentially serious complication of laparoscopic surgery. Data about drain site hernia after laparoscopic surgery is scarce and anecdotal. CASE PRESENTATION: we report an uncommon case of drain site hernia in a man undergone laparoscopic left colectomy for a colonic adenocarcinoma who developed small bowel herniation in a 10 mm port site, in which a 24 FR drain was inserted leaving a real free space of 2 mm. DISCUSSION: laparoscopic approach has gained widespread acceptance in each surgical fields because of the perceived better postoperative outcomes in terms of less pain, faster recovery, and lower risk of incisional hernia...
January 9, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29341941/cauda-equina-syndrome-due-to-lumbar-disc-herniation-a-review-of-literature
#14
Stylianos Kapetanakis, Constantinos Chaniotakis, Constantinos Kazakos, Jannis V Papathanasiou
Cauda equina syndrome (CES) is a rare neurologic condition that is caused by compression of the cauda equina. Cauda equina consists of spinal nerves L2-L5, S1-S5 and the coccygeal nerve. The compression of these nerve roots can be caused mainly by lumbar disc herniation (45% of all causes). The diagnosis consists of two critical points: a) detailed history and physical examination and b) MRI or CT. The gold standard of the treatment of this syndrome is the surgical approach in combination with the timing of onset of symptoms...
December 20, 2017: Folia Medica
https://www.readbyqxmd.com/read/29341044/antenatal-medical-therapies-to-improve-lung-development-in-congenital-diaphragmatic-hernia
#15
Aidan Kashyap, Philip DeKoninck, Kelly Crossley, Marta Thio, Graeme Polglase, Francesca Maria Russo, Jan Deprest, Stuart Hooper, Ryan Hodges
Congenital diaphragmatic hernia (CDH) is a birth defect characterized by failed closure of the diaphragm, allowing abdominal viscera to herniate into the thoracic cavity and subsequently impair pulmonary and vascular development. Despite improving standardized postnatal management, there remains a population of severe CDH for whom postnatal care falls short. In these severe cases, antenatal surgical intervention (fetoscopic endoluminal tracheal occlusion [FETO]) may improve survival; however, FETO increases the risk of preterm delivery, is not widely offered, and still fails in half of cases...
January 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29341038/-the-use-of-deep-inferior-epigastric-vessels-to-revascularise-free-flaps-for-reconstruction-of-complex-oncosurgical-defects-of-the-thigh-and-the-abdomen
#16
F Simunovic, U Wittel, B Passlick, S Wiesemann, M Czerny, M Südkamp, G B Stark, H Bannasch
BACKGROUND: The resection of large soft-tissue sarcoma requires reconstruction with free flaps. The choice of recipient vessels is crucial for the success of surgery. PATIENTS: We report four cases with large soft-tissue sarcomas with complex anatomical relationships: two tumors of the thigh surrounding the femoral neurovascular structures and two tumors of the abdomen with infiltration of the thorax and the abdomen. All cases received multimodal interdisciplinary treatment...
January 16, 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29336816/traumatic-thoracic-rib-cage-hernias-operative-management-and-proposal-for-a-new-anatomic-based-grading-system
#17
John Kuckelman, Riyad Karmy-Jones, Elizabeth Windell, Seth Izenberg, Jean-Stephane David, William Long, Matthew J Martin
BACKGROUND: Traumatic Rib Cage Hernias (TRCH) requiring operative repair are rare and there is currently no literature to guiding surgical management. METHODS: Perioperative review of TRCH over 32 years. Five operative grades were developed based on extent of tissue/bone damage, size, and location. RESULTS: Twenty-four patients (20 blunt, 4 penetrating) underwent operative repair. Lung was the herniated organ in 88% with a median of 4 rib fractures and average size of 60...
January 5, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29334542/medial-buttressing-in-orbital-blowout-fractures
#18
Sathyadeepak Ramesh, Christine Bokman, Hamzah Mustak, Christopher Lo, Robert Goldberg, Daniel Rootman
PURPOSE: To study whether ethmoidectomy predisposes the orbit to medial wall fracture with lesser trauma. METHODS: An interventional cadaver study of 5 heads (10 orbits); the left or right orbit was randomized to undergo endoscopic complete ethmoidectomy with the fellow orbit as control. Fractures were induced with direct globe trauma, and heads underwent CT scanning. Energy to induce fracture, peak orbital pressure at time of fracture, fracture pattern, and volume of herniated tissue were measured and analyzed...
January 12, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29332784/air-transport-of-a-patient-with-impending-cerebral-herniation-from-tension-pneumocephalus
#19
Etzer Augustin, Michael Karsy, Jim Bryan, Jian Guan, Richard H Schmidt
Tension pneumocephalus is a rare but dangerous complication of craniotomy, sinus surgery, and traumatic cranial injury. Compared with simple pneumocephalus, which often resolves spontaneously over the course of a few days, tension pneumocephalus tends to increase with ongoing cerebrospinal fluid leak and requires immediate neurosurgical treatment to prevent cerebral herniation. Air transport of patients with tension pneumocephalus for neurosurgical care entails a risk of neurologic worsening because of changes in ambient air pressure with altitude and cabin pressurization...
January 2018: Air Medical Journal
https://www.readbyqxmd.com/read/29332056/ozone-injection-with-or-without-percutaneous-microdiscectomy-for-treatment-of-cervical-disc-herniation
#20
Haiting Wang, Yi Zhou, Zhongpu Jiang
OBJECTIVE: This retrospective study compared the efficacy of combined percutaneous ozone injection and percutaneous discectomyto percutaneous ozone injection alone for the treatment of cervical disc herniation. METHODS: Patients with cervical disc herniation who were enrolled in our hospital from October 2010 to June 2015 were divided into two groups: 1) treated with percutaneous ozone injection alone (control; n= 19); and 2) those treated with combined ozone injection and percutaneous microdiscectomy (combined treatment; n= 28)...
December 29, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
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