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Outcome after repair of tetralogy of fallot

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https://www.readbyqxmd.com/read/27893189/a-first-population-based-long-term-outcome-study-in-adults-with-repaired-tetralogy-of-fallot-in-malta
#1
Maryanne Caruana, Victor Grech
OBJECTIVES: To determine overall and reintervention-free survival for repaired Maltese tetralogy of Fallot patients and to investigate the potential impact of gender, age at repair, genetic syndromes, previous palliation, and type of repair on these outcomes. DESIGN: All 130 tetralogy of Fallot patients born before the end of 1997 included in the local database were extracted. Surgical repair type, age at repair and operative survival were analyzed among the 103/130 repaired patients...
November 28, 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27876287/mid-term-outcomes-of-common-congenital-heart-defects-corrected-through-a-right-subaxillary-thoracotomy
#2
Guoying An, Hongyu Zhang, Shanguang Zheng, Weixin Wang, Liming Ma
OBJECTIVE: To evaluate the mid-term outcomes of the correction of various congenital heart defects through a right subaxillary thoracotomy. METHODS: Between June 2004 and April 2014, all eligible patients were those with a common congenital heart defect corrected via an approach through a right subaxillary thoracotomy. There were 836 patients (male 417, female 419; median age, 3.5 years; median weight 13.6kg) with ventricular septal defect (VSD) closure (523 patients), atrial septal defect (ASD) closure (235 patients), partial atrioventricular canal (PAVC) correction (55 patients), mild tetralogy of Fallot (TOF) (23 patients)...
February 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27782857/increased-left-ventricular-myocardial-extracellular-volume-is-associated-with-longer-cardiopulmonary-bypass-times-biventricular-enlargement-and-reduced-exercise-tolerance-in-children-after-repair-of-tetralogy-of-fallot
#3
Eugénie Riesenkampff, Wietske Luining, Mike Seed, Paweena Chungsomprasong, Cedric Manlhiot, Bernadette Elders, Brian W McCrindle, Shi-Joon Yoo, Lars Grosse-Wortmann
BACKGROUND: Unfavorable left ventricular (LV) remodelling may be associated with adverse outcomes after Tetralogy of Fallot (TOF) repair. We sought to assess T1 cardiovascular magnetic resonance (CMR) markers of diffuse LV myocardial fibrosis in children after TOF repair, and associated factors. METHODS: In this prospective, cross-sectional study, native (=non-contrast) T1 times and extracellular volume fraction (ECV) were quantified in the LV myocardium using CMR...
October 26, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27756471/effects-of-angle-correction-angioplasty-for-pulmonary-artery-stenosis-with-tetralogy-of-fallot
#4
Woo Sung Jang, Woong-Han Kim, Sungkyu Cho
BACKGROUND: Left pulmonary artery (LPA) stenosis with acute angulation is a common cause of reoperation after tetralogy of Fallot repair. We therefore investigated surgical outcomes of acute-angle correction angioplasty. METHODS: Between 2005 and 2012, 53 patients underwent operation for LPA stenosis as a concurrent procedure. We divided the patients into two groups according to the LPA ostium angulation: group I (acute angle, acute-angle correction angioplasty, n = 29) and group II (obtuse angle, conventional patch angioplasty, n = 24), encompassing subgroup type I (focal stenosis) and type II (diffuse stenosis)...
October 15, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27692918/optimal-timing-for-elective-early-primary-repair-of-tetralogy-of-fallot-analysis-of-intermediate-term-outcomes
#5
Michael E A Cunningham, Mary T Donofrio, Syed Murfad Peer, David Zurakowski, Richard A Jonas, Pranava Sinha
BACKGROUND: We have previously demonstrated that early primary repair of tetralogy of Fallot with pulmonary stenosis (TOF) can be safely performed without increase in hospital resource utilization or compromise to surgical technical performance scores (TPS). We sought to identify the optimal timing for elective early primary repair of TOF with respect to intermediate-term reintervention. METHODS: Retrospective review of all patients with TOF undergoing elective primary repair between September 2004 and December 2013 was performed...
September 28, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27692233/long-term-outcome-of-patients-with-complete-atrioventricular-septal-defect-combined-with-the-tetralogy-of-fallot-staged-repair-is-not-inferior-to-primary%C3%A2-repair
#6
Keti Vitanova, Julie Cleuziou, Christian Schreiber, Thomas Günther, Jelena Pabst von Ohain, Jürgen Hörer, Rüdiger Lange
BACKGROUND: Primary repair is the preferred strategy for surgical treatment of complete atrioventricular septal defect combined with the tetralogy of Fallot. However, a staged approach may be preferable for very small or cyanotic infants. The long-term outcomes of infants undergoing staged vs primary repair were compared. METHODS: Data from 47 patients with complete atrioventricular septal defect combined with the tetralogy of Fallot who were operated on at our institution between 1974 and 2013 were reviewed...
September 27, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27647341/constrictive-pericarditis-following-correction-of-partial-anomalous-pulmonary-venous-drainage
#7
Chin Siang Ong, Sriram Shankar, James W L Yip, Edgar L W Tay, Lynette L S Teo, Swee Chye Quek
We report the case of a 23-year-old man who developed constrictive pericarditis within four months after pulmonary valve replacement and repair of partial anomalous pulmonary venous connection. He had previously undergone repair of tetralogy of Fallot in infancy. After an unsuccessful trial of medical management for persistent right heart failure, magnetic resonance imaging was done, which showed a thickened pericardium. He underwent a radical pericardiectomy with a good outcome. The case is presented to illustrate a less well-recognized cause of cardiac failure following congenital cardiac surgery, which may otherwise be attributed to the failure of surgery or residual complications...
September 19, 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/27627806/patient-specific-mri-based-right-ventricle-models-using-different-zero-load-diastole-and-systole-geometries-for-better-cardiac-stress-and-strain-calculations-and-pulmonary-valve-replacement-surgical-outcome-predictions
#8
Dalin Tang, Pedro J Del Nido, Chun Yang, Heng Zuo, Xueying Huang, Rahul H Rathod, Vasu Gooty, Alexander Tang, Zheyang Wu, Kristen L Billiar, Tal Geva
BACKGROUND: Accurate calculation of ventricular stress and strain is critical for cardiovascular investigations. Sarcomere shortening in active contraction leads to change of ventricular zero-stress configurations during the cardiac cycle. A new model using different zero-load diastole and systole geometries was introduced to provide more accurate cardiac stress/strain calculations with potential to predict post pulmonary valve replacement (PVR) surgical outcome. METHODS: Cardiac magnetic resonance (CMR) data were obtained from 16 patients with repaired tetralogy of Fallot prior to and 6 months after pulmonary valve replacement (8 male, 8 female, mean age 34...
2016: PloS One
https://www.readbyqxmd.com/read/27549809/left-and-right-ventricular-dyssynchrony-and-strains-from-cardiovascular-magnetic-resonance-feature-tracking-do-not-predict-deterioration-of-ventricular-function-in-patients-with-repaired-tetralogy-of-fallot
#9
Linyuan Jing, Gregory J Wehner, Jonathan D Suever, Richard J Charnigo, Sudad Alhadad, Evan Stearns, Dimitri Mojsejenko, Christopher M Haggerty, Kelsey Hickey, Anne Marie Valente, Tal Geva, Andrew J Powell, Brandon K Fornwalt
BACKGROUND: Patients with repaired tetralogy of Fallot (rTOF) suffer from progressive ventricular dysfunction decades after their surgical repair. We hypothesized that measures of ventricular strain and dyssynchrony would predict deterioration of ventricular function in patients with rTOF. METHODS: A database search identified all patients at a single institution with rTOF who underwent cardiovascular magnetic resonance (CMR) at least twice, >6 months apart, without intervening surgical or catheter procedures...
August 22, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27528445/perioperative-echocardiography-derived-right-ventricle-function-parameters-and-early-outcomes-after-tetralogy-of-fallot-repair-in-mid-childhood-a-single-center-prospective-observational-study
#10
Ravi Raj, Goverdhan Dutt Puri, Aveek Jayant, Shyam Kumar Singh Thingnam, Rana Sandip Singh, Manoj Kumar Rohit
BACKGROUND: Right ventricular (RV) function alterations are invariably present in all patients after tetralogy of Fallot (TOF) repair. Unlike the developed world where most of the patients with TOF are corrected in infancy, average age of presentation and thus surgery for these patients in the developing world may be higher. We aimed to study the correlation between RV function parameters such as tricuspid annular peak systolic excursion (TAPSE), fractional area change (FAC), and tricuspid annular peak systolic velocity (S') with early outcome variables after intracardiac repair for TOF...
November 2016: Echocardiography
https://www.readbyqxmd.com/read/27329296/approach-to-residual-pulmonary-valve-dysfunction-in-adults-with-repaired-tetralogy-of-fallot
#11
REVIEW
Yuli Y Kim, Emily Ruckdeschel
Residual right ventricular outflow tract and pulmonary valve disease is common in adults with repaired tetralogy of Fallot. Chronic severe pulmonary regurgitation as a result of surgical repair can lead to myriad complications including right ventricular dysfunction, decreased exercise tolerance, right heart failure and symptomatic arrhythmias. The aim of restoring pulmonary valve integrity is to preserve right ventricular size and function with the intent of mitigating the development of symptoms and poor long-term outcomes...
October 1, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27234868/long-term-follow-up-of-implantable-cardioverter-defibrillators-in-adult-congenital-heart-disease-patients-indications-and-outcomes
#12
Sandhya Santharam, Lucy Hudsmith, Sara Thorne, Paul Clift, Howard Marshall, Joseph De Bono
AIMS: Ventricular arrhythmias are a major cause of mortality in adult congenital heart disease (ACHD) patients. The European Society of Cardiology guidelines state that implantable cardioverter-defibrillators (ICD) should be considered in patients with congenital heart disease following spontaneous sustained ventricular tachycardia (VT) or cardiac arrest and in patients at presumed high risk. This study sought to analyse the circumstances in which ACHD patients received ICD and to assess outcomes of ICD implantation, including therapies delivered and the rate of complications...
May 26, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27173073/early-extubation-after-repair-of-tetralogy-of-fallot-and-the-fontan-procedure-an-analysis-of-the-society-of-thoracic-surgeons-congenital-heart-surgery-database
#13
William T Mahle, Jeffrey P Jacobs, Marshall L Jacobs, Sunghee Kim, Paul M Kirshbom, Sara K Pasquali, Erle H Austin, Kirk R Kanter, Susan C Nicolson, Kevin D Hill
BACKGROUND: There is increasing interest in reducing the duration of mechanical ventilation after pediatric cardiac operations. However, the contemporary use of an early extubation strategy and its effect on clinical outcomes is poorly understood. METHODS: Data from The Society of Thoracic Surgeons Congenital Heart Surgery Database (2010 to 2013) were analyzed to determine the association of early extubation with postoperative length of stay (PLOS). Two operations were analyzed: complete repair of tetralogy of Fallot (TOF) in patients older than 45 days and the Fontan procedure...
September 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27126593/cardiac-contractility-modulation-in-a-model-of-repaired-tetralogy-of-fallot-a-sheep-model
#14
Francois Roubertie, Romain Eschalier, Adlane Zemmoura, Jean-Benoit Thambo, Caroline Rooryck, Louis Labrousse, Sylvain Ploux, Philippe Ritter, Michel Haïssaguerre, Pierre Dos Santos, Pierre Bordachar
The onset of right ventricular dysfunction in patients presenting with congenital heart disease is associated with a dismal long-term outcome and often represents a therapeutic dead end. Our study had several objectives: (1) to analyse the anatomical, functional, histological and cellular characteristics of an animal model of repaired tetralogy of Fallot with right ventricular dysfunction (2) to test the new electrical treatment known as cardiac contractility modulation in this animal model. Seven sheep underwent a first surgery at the age of three weeks aiming to mimic the characteristics of a repaired tetralogy of Fallot...
June 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/26927857/nt-probnp-indicates-left-ventricular-impairment-and-adverse-clinical-outcome-in-patients-with-tetralogy-of-fallot-and-pulmonary-regurgitation
#15
Mechthild Westhoff-Bleck, Finn Kornau, Arash Haghikia, Alexander Horke, Harald Bertram, Jens Treptau, Julian Widder, Johann Bauersachs, Michael-Ulrich Brehm
BACKGROUND: The goal of this study was to interrelate N-terminal B-type natriuretic peptide (NT-proBNP) levels and cardiac magnetic resonance imaging-derived ventricular function, mass, and volumes in adults with pulmonary regurgitation after Fallot repair and to evaluate the prognostic relevance of these parameters regarding adverse clinical outcome. METHODS: Eighty-one patients (aged 26.3 ± 7.4 years; male sex, 45.7%; New York Heart Association class I, 72.8%; pulmonary valve velocity, < 3 m/s) were included...
December 1, 2015: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/26856227/novel-mechanisms-for-cerebral-blood-flow-regulation-in-patients-with-congenital-heart-disease
#16
Hirofumi Saiki, Masaya Sugimoto, Seiko Kuwata, Clara Kurishima, Yoichi Iwamoto, Hirotaka Ishido, Satoshi Masutani, Hideaki Senzaki
BACKGROUND: The mechanisms that regulate cerebral flow in patients after surgery for congenital heart diseases (CHDs) remain poorly understood. We tested our hypothesis that postoperative patients with CHD have disease- or hemodynamic-specific compensatory mechanisms for maintaining cerebral perfusion. METHODS: A total of 89 children with specific hemodynamics including Glenn (n = 14), Fontan (n = 19), repaired tetralogy of Fallot (n = 24), and control patients (n = 32) were enrolled...
February 2016: American Heart Journal
https://www.readbyqxmd.com/read/26843460/myocardial-oxidative-stress-in-infants-undergoing-cardiac-surgery
#17
Nathaniel Sznycer-Taub, Stewart Mackie, Yun-Wen Peng, Janet Donohue, Sunkyung Yu, Ranjit Aiyagari, John Charpie
Cardiac surgery for congenital heart disease often necessitates a period of myocardial ischemia during cardiopulmonary bypass and cardioplegic arrest, followed by reperfusion after aortic cross-clamp removal. In experimental models, myocardial ischemia-reperfusion is associated with significant oxidative stress and ventricular dysfunction. A prospective observational study was conducted in infants (<1 year) who underwent elective surgical repair of a ventricular septal defect (VSD) or tetralogy of Fallot (TOF)...
April 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/26818850/safety-and-efficacy-of-prophylactic-amiodarone-in-preventing-early-junctional-ectopic-tachycardia-jet-in-children-after-cardiac-surgery-and-determination-of-its-risk-factor
#18
Doaa El Amrousy, Walid Elshehaby, Wael El Feky, Nagat S Elshmaa
Postoperative arrhythmia is a common complication after open heart surgery in children. JET is the most common and dangerous arrhythmia. We aimed to assess safety and efficacy of prophylactic amiodarone in preventing JET in children underwent cardiac surgery and to assess risk factors for JET among our patients. In total, 117 children who underwent cardiac surgery for CHD at Tanta University Hospital from October 2011 to April 2015 were divided in two groups; amiodarone group (65 patients) was given prophylactic amiodarone intraoperatively and placebo group (52 patients)...
April 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/26548998/mechanical-stress-is-associated-with-right-ventricular-response-to-pulmonary-valve-replacement-in-patients-with-repaired-tetralogy-of-fallot
#19
Dalin Tang, Chun Yang, Pedro J del Nido, Heng Zuo, Rahul H Rathod, Xueying Huang, Vasu Gooty, Alexander Tang, Kristen L Billiar, Zheyang Wu, Tal Geva
OBJECTIVE: Patients with repaired tetralogy of Fallot account for a substantial proportion of cases with late-onset right ventricular failure. The current surgical approach, which includes pulmonary valve replacement/insertion, has yielded mixed results. Therefore, it may be clinically useful to identify parameters that can be used to predict right ventricular function response to pulmonary valve replacement. METHODS: Cardiac magnetic resonance data before and 6 months after pulmonary valve replacement were obtained from 16 patients with repaired tetralogy of Fallot (8 male, 8 female; median age, 42...
March 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26152515/palliative-balloon-pulmonary-valvuloplasty-for-infants-with-unrestrictive-ventricular-septal-defect-or-single-ventricle-associated-with-severe-pulmonary-stenosis
#20
Ramiro W Lizano Santamaria, Matthew J Gillespie, Yoav Dori, Jonathan J Rome, Andrew C Glatz
BACKGROUND: Symptomatic infants with unrestrictive ventricular septal defect (VSD) or single ventricle with severe pulmonary stenosis (PS) are typically treated surgically. High surgical risk infants may benefit from catheter-based palliative pulmonary valvuloplasty. METHODS: We retrospectively reviewed all patients with severe PS associated with unrestrictive VSD or single ventricle who underwent palliative pulmonary valvuloplasty as initial management and describe outcomes...
November 2015: Catheterization and Cardiovascular Interventions
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