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https://www.readbyqxmd.com/read/27902586/neurological-psychological-and-cognitive-disorders-in-patients-with-chronic-kidney-disease-on-conservative-and-replacement-therapy
#1
Silvia Lai, Oriano Mecarelli, Patrizia Pulitano, Roberto Romanello, Leonardo Davi, Alessia Zarabla, Amalia Mariotti, Maria Carta, Giorgia Tasso, Luca Poli, Anna Paola Mitterhofer, Massimo Testorio, Nicla Frassetti, Paola Aceto, Alessandro Galani, Carlo Lai
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients. The aim of this study was to assess the neurological, psychological, and cognitive imbalance in patients with CKD on conservative and replacement therapy.Seventy-four clinically stable patients affected by CKD on conservative therapy, replacement therapy (hemodialysis (HD), peritoneal dialysis (PD)), or with kidney transplantation (KT) and 25 healthy controls (HC), matched for age and sex were enrolled...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27901521/electronic-cigarette-use-in-patients-with-schizophrenia-prevalence-and-attitudes
#2
Brian J Miller, Alexandre Wang, Joyce Wong, Nina Paletta, Peter F Buckley
BACKGROUND: Smoking is highly prevalent in patients with schizophrenia. Electronic cigarettes (e-cigarettes) are becoming increasingly popular among smokers. Surveys indicate overall favorable attitudes toward the use of e-cigarettes to reduce or quit smoking, relieve withdrawal symptoms, and with respect to perceived health risks; however, less is known about their use in patients with schizophrenia. In the present study, we investigated the prevalence of and attitudes toward e-cigarettes in patients with schizophrenia...
November 1, 2016: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/27880771/differences-in-connection-strength-between-mental-symptoms-might-be-explained-by-differences-in-variance-reanalysis-of-network-data-did-not-confirm-staging
#3
Berend Terluin, Michiel R de Boer, Henrica C W de Vet
BACKGROUND: The network approach to psychopathology conceives mental disorders as sets of symptoms causally impacting on each other. The strengths of the connections between symptoms are key elements in the description of those symptom networks. Typically, the connections are analysed as linear associations (i.e., correlations or regression coefficients). However, there is insufficient awareness of the fact that differences in variance may account for differences in connection strength...
2016: PloS One
https://www.readbyqxmd.com/read/27856683/the-challenging-experience-questionnaire-characterization-of-challenging-experiences-with-psilocybin-mushrooms
#4
Frederick S Barrett, Matthew P Bradstreet, Jeannie-Marie S Leoutsakos, Matthew W Johnson, Roland R Griffiths
Acute adverse psychological reactions to classic hallucinogens ("bad trips" or "challenging experiences"), while usually benign with proper screening, preparation, and support in controlled settings, remain a safety concern in uncontrolled settings (such as illicit use contexts). Anecdotal and case reports suggest potential adverse acute symptoms including affective (panic, depressed mood), cognitive (confusion, feelings of losing sanity), and somatic (nausea, heart palpitation) symptoms. Responses to items from several hallucinogen-sensitive questionnaires (Hallucinogen Rating Scale, the States of Consciousness Questionnaire, and the Five-Dimensional Altered States of Consciousness questionnaire) in an Internet survey of challenging experiences with the classic hallucinogen psilocybin were used to construct and validate a Challenging Experience Questionnaire...
December 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27853447/corrigendum-paranoia-as-an-antecedent-and-consequence-of-getting-ahead-in-organizations-time-lagged-effects-between-paranoid-cognitions-self-monitoring-and-changes-in-span-of-control
#5
https://www.readbyqxmd.com/read/27829400/is-schizophrenia-disappearing-the-rise-and-fall-of-the-diagnosis-of-functional-psychoses-an-essay
#6
Per Bergsholm
BACKGROUND: The categories of functional psychoses build on views of influential professionals. There have long been four main categories - affective, schizophrenic, schizoaffective/cycloid/reactive/polymorphic, and delusional/paranoid psychoses. The last three are included in "psychotic disorders". However, this dichotomy and the distinctions between categories may have been over-estimated and contributed to lack of progress. TEN TOPICS RELEVANT FOR THE DIAGNOSIS OF FUNCTIONAL PSYCHOSES: 1...
November 9, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27821329/an-investigation-into-the-jumping-to-conclusions-bias-in-social-anxiety
#7
Kristy M Johnstone, Junwen Chen, Ryan P Balzan
'Jumping-to-Conclusions' (JTC) is a data-gathering bias characterised by hasty decision-making, and is typically seen in individuals with high levels of delusions or paranoia. JTC has also been found in people with high trait and state anxiety. The present study aimed to explore the relationship between JTC and trait social anxiety and state anxiety, given paranoia is common in both social anxiety and psychotic disorders. One-hundred-and-eighty-six undergraduate students were allocated to a manipulation or control condition, and classified as high or low socially anxious...
November 4, 2016: Consciousness and Cognition
https://www.readbyqxmd.com/read/27817827/do-depressive-symptoms-predict-paranoia-or-vice-versa
#8
Steffen Moritz, Anja S Göritz, Benjamin McLean, Stefan Westermann, Jeannette Brodbeck
BACKGROUND AND OBJECTIVES: Affective versus nonaffective psychoses are today no longer regarded as mutually exclusive disorders. Theorists have recently highlighted the role of affective symptoms in the formation of paranoid beliefs, particularly negative beliefs about the self, interpersonal sensitivity, sleep disturbances, and worrying, which exist along a continuum in the general population. For the present study, we tested the bidirectional causal relationships between paranoia and affect...
October 18, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27799294/structure-activity-relationships-of-substituted-cathinones-with-transporter-binding-uptake-and-release
#9
Amy J Eshleman, Katherine M Wolfrum, John F Reed, Sunyoung O Kim, Tracy Swanson, Robert A Johnson, Aaron J Janowsky
Synthetic cathinones are components of "bath salts" and have physical and psychological side effects including hypertension, paranoia, and hallucinations. Herein we report interactions of 20 "bath salt" components with human dopamine, serotonin, and norepinephrine transporters (hDAT, hSERT, and hNET, respectively) heterologously expressed in HEK 293 cells. Transporter inhibitors had nanomolar to micromolar affinities (Ki values) at radioligand binding sites, with relative affinities of hDAT>hNET>hSERT for α-PPP, α-PBP, α-PHP, PV-8, 3,4-MDPPP, 3,4-MDPBP, 4-MePPP, α-PVP, 4-MeO- α-PVP, α-PVT and pentedrone, and hDAT>hSERT>hNET for pentylone...
October 31, 2016: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/27793241/seizure-due-to-multiple-drugs-intoxication-a-case-report
#10
Handan Gulec, Munire Babayigit, Aysun Kurtay, Mehmet Sahap, Fatma Ulus, Zehra Tutal, Eyup Horasanli
The mechanism of the antidepressant effect of bupropion is not fully understood. Besides, using it in the treatment of depression, it is found to be effective in reducing withdrawal symptoms due to smoking cessation. A 28-year-old female patient with a history of depression was admitted to emergency department an hour after ingestion of bupropion, quetiapine, and levothyroxine in high doses to commit suicide. While accepting her into the Intensive Care Unit, she was awake, alert, disoriented and agitated. After 2h, the patient had a generalized tonic-clonic seizure...
November 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27790150/excited-delirium-and-sudden-death-a-syndromal-disorder-at-the-extreme-end-of-the-neuropsychiatric-continuum
#11
REVIEW
Deborah C Mash
Over the past decade, the excited delirium syndrome (ExDS) has raised continued controversy regarding the cause and manner of death of some highly agitated persons held in police custody, restrained or incapacitated by electrical devices. At autopsy, medical examiners have difficulty in identifying an anatomic cause of death, but frequently cite psychostimulant intoxication as a contributing factor. The characteristic symptoms of ExDS include bizarre and aggressive behavior, shouting, paranoia, panic, violence toward others, unexpected physical strength, and hyperthermia...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27768984/a-randomized-controlled-trial-of-heart-rate-variability-biofeedback-for-psychotic-symptoms
#12
Annika Clamor, Julian Koenig, Julian F Thayer, Tania M Lincoln
Arousal and the way it is coped with are relevant to the emergence of psychotic symptoms. Heart rate variability (HRV) stems from autonomic responses to environmental demands such as stress and is an index of physiological arousal, adaptability, and homeostatic reflexes forming autonomic balance. A randomized-controlled between-subjects trial that compared HRV-biofeedback (BF) to an active relaxation and to a waiting control condition was conducted in a sample with attenuated subclinical psychotic symptoms (N = 84)...
October 11, 2016: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/27739073/narratives-of-self-neglect-patterns-of-traumatic-personal-experiences-and-maladaptive-behaviors-in-cognitively-intact-older-adults
#13
Cynthia Lien, Tony Rosen, Elizabeth M Bloemen, Robert C Abrams, Maria Pavlou, Mark S Lachs
OBJECTIVES: To identify patterns of personal experience or behavior in self-neglect by exploring narratives of cognitively intact older adults. DESIGN: Descriptive study involving semistructured interviews and unstructured narratives. SETTING: A parent study of self-neglect characteristics. PARTICIPANTS: Cognitively intact, self-neglecting older adults referred from 11 community-based senior services agencies (N = 69)...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27734824/-cannabinoid-and-cathinone-designer-drugs-the-workings-and-selected-methods-of-analysis
#14
Jadwiga Nędza, Renata Polaniak, Rafał J Bułdak, Milena Majchrzak, Joanna Margasiń-Ska, Marcin Rojkiewicz, Rafał Celiński, Elżbieta Grochowska-Niedworok
Recently, there has been an increase in the consumption of designer drugs, substances aimed at producing psychoactive, energizing, euphoric or anesthetic effects. Designer drugs are substitutes of actual narcotics, whose possession is banned under Polish law according to the Act of 29 July 2005. The latest reports suggest that the number of synthetic psychoactive substances is increasing. In the span of 2012, a total of 28 new synthetic cannabinoids were discovered in member states of the European Union. Synthetic psychoactive substances appear in different forms on the market: tablets (often very colourful and interestingly-shaped), seeds, dried product (sprayed with synthetic substance and redried), crystals or powder...
July 29, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27715709/acute-effects-of-synthetic-cannabinoids-update-2015
#15
Juliana Tournebize, Valérie Gibaja, Jean-Pierre Kahn
BACKGROUND: Cannabis is the most widely used illicit drug in the United States and Europe. In recent years, a range of new substances with cannabis-like effects-known as synthetic cannabinoids (SCs)-have suddenly burst on the drug scene. However, there is limited information about the clinical hazards linked to the use of these emerging substances. This review summarizes the literature to date relating the health effects of SCs. METHOD: A systematic literature review of original case studies was performed using PubMed and Web of Science (January 1980-July 2015)...
August 11, 2016: Substance Abuse
https://www.readbyqxmd.com/read/27713724/paranoia-as-an-antecedent-and-consequence-of-getting-ahead-in-organizations-time-lagged-effects-between-paranoid-cognitions-self-monitoring-and-changes-in-span-of-control
#16
Niels Van Quaquebeke
A 6-month, time-lagged online survey among 441 employees in diverse industries was conducted to investigate the role paranoia plays as an antecedent and as a consequence of advancement in organizations. The background of the study is the argument that it requires active social sense-making and behavioral adaptability to advance in organizations. The present paper thus explores the extent to which employees' paranoid cognitions-representative of a heightened albeit suspicious sense-making and behavioral adaptability-link with their advancement in organizations (operationalized as changes in afforded span of control), both as an antecedent and an outcome...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27686877/-many-die-in-the-hurricane-an-interpretative-phenomenological-analysis-of-adults-with-psychosis-and-a-history-of-childhood-physical-abuse
#17
J E Rhodes, L J Healey
The study aimed to investigate the experience of adults with a diagnosis of psychosis and who have survived childhood physical abuse. We interviewed eight participants and used interpretative phenomenological analysis to generate themes. The main themes were of perceiving an everyday world of aggression and contempt by others, pervasive mistrust, feeling isolated and for some, attacking oneself with hate. Most participants were also able to reflect on what they saw as 'paranoia' or 'voices'. Paranoia was described as a fluctuating compulsive 'thread' of meaning, feeling and sometimes a transformation of the self...
September 29, 2016: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/27672526/autoimmune-schizophrenia-psychiatric-manifestations-of-hashimoto-s-encephalitis
#18
Ali S Haider, Maryam Alam, Ebun Adetutu, Richa Thakur, Caleb Gottlich, Danielle L DeBacker, Lianne Marks
Hashimoto's encephalitis (HE), also known as steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), can be a debilitating manifestation of an autoimmune reaction against the thyroid that is often under-diagnosed primarily due to a lack of definitive diagnostic criteria. This is a case of a 52-year-old woman who has been diagnosed with HE after presenting with recurrent and severe psychosis in conjunction with paranoia and a thyroidopathy. Her symptoms are chronic, having first been documented as presenting 15 years prior and showing progressive exacerbation in both frequency and severity...
July 5, 2016: Curēus
https://www.readbyqxmd.com/read/27649527/the-dynamics-of-attachment-insecurity-and-paranoid-thoughts-an-experience-sampling-study
#19
Katarzyna Sitko, Filippo Varese, William Sellwood, Amy Hammond, Richard Bentall
It has been proposed that insecure attachment can have adverse effects on the course of psychosis once symptoms have emerged. There is longitudinal evidence that increased insecure attachment is associated with increased severity of psychotic symptoms. The present study examined whether in the flow of daily life attachment insecurity fluctuates, whether elevated stress precedes the occurrence of attachment insecurity, and whether elevated attachment insecurity precedes the occurrence of paranoia. Twenty clinical participants with a psychosis-spectrum diagnosis and twenty controls were studied over six consecutive days using the experience sampling method (ESM)...
September 3, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27643994/an-n-1-clinical-network-analysis-of-symptoms-and-treatment-in-psychosis
#20
Maarten Bak, Marjan Drukker, Laila Hasmi, Jim van Os
INTRODUCTION: Dynamic relationships between the symptoms of psychosis can be shown in individual networks of psychopathology. In a single patient, data collected with the Experience Sampling Method (ESM-a method to construct intensive time series of experience and context) can be used to study lagged associations between symptoms in relation to illness severity and pharmacological treatment. METHOD: The patient completed, over the course of 1 year, for 4 days per week, 10 daily assessments scheduled randomly between 10 minutes and 3 hours apart...
2016: PloS One
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