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https://www.readbyqxmd.com/read/28917974/cross-cultural-analysis-of-medicinal-plants-commonly-used-in-ethnoveterinary-practices-at-south-waziristan-agency-and-bajaur-agency-federally-administrated-tribal-areas-fata-pakistan
#1
Muhammad Abdul Aziz, Muhammad Adnan, Amir Hasan Khan, Muhammad Sufyan, Shahid Niaz Khan
ETHNOPHARMACOLOGICAL RELEVANCE: In remote areas, medicinal plants have an imperative role in curing various livestock's ailments. In Pakistan, people residing in remote areas including South Waziristan Agency and Bajaur Agency depend on traditional herbal remedies for treating their domestic animals. Medicinal plants are an important part of the medical system in these Agencies. The prime goal of the current study is to explore the ethnoveterinary practices in the two regions and discuss cross-cultural consensus on the use of medicinal plants...
September 13, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28915537/mta1-expression-in-human-cancers-clinical-and-pharmacological-significance
#2
REVIEW
Vijaya Lakshmi Malisetty, Vasudevarao Penugurti, Prashanth Panta, Suresh Kumar Chitta, Bramanandam Manavathi
Remarkably, majority of the cancer deaths are due to metastasis, not because of primary tumors. Metastasis is one of the important hallmarks of cancer. During metastasis invasion of primary tumor cells from the site of origin to a new organ occurs. Metastasis associated proteins (MTAs) are a small family of transcriptional coregulators that are closely associated with tumor metastasis. These proteins are integral components of nuclear remodeling and deacetylation complex (NuRD). By virtue of being integral components of NuRD, these proteins regulate the gene expression by altering the epigenetic changes such as acetylation and methylation on the target gene chromatin...
September 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28911247/metabolic-pathways-and-pharmacokinetics-of-natural-medicines-with-low-permeability
#3
Mei Zeng, Lan Yang, Dan He, Yao Li, Mingxin Shi, Jingqing Zhang
Drug metabolism plays an important role in the drug disposal process. Differences in pharmacokinetics among individuals are the basis for personalized medicine. Natural medicines, formed by long-term evolution of nature, prioritize the action of a target protein with a drug. Natural medicines are valued for structural diversity, low toxicity, low cost, and definite biological activities. Metabolic pathway and pharmacokinetic research of natural medicines is highly beneficial for clinical dose adjustment and the development of personalized medicine...
September 14, 2017: Drug Metabolism Reviews
https://www.readbyqxmd.com/read/28910997/paediatric-nuclear-medicine-imaging
#4
Lorenzo Biassoni, Marina Easty
Background: Nuclear medicine imaging explores tissue viability and function by using radiotracers that are taken up at cellular level with different mechanism. This imaging technique can also be used to assess blood flow and transit through tubular organs. Nuclear medicine imaging has been used in paediatrics for decades and this field is continuously evolving. Sources of data: The data presented comes from clinical experience and some milestone papers on the subject...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28905803/diagnosis-and-treatment-of-gastroesophageal-reflux-disease-complicated-by-barrett-s-esophagus
#5
Andriy Stasyshyn
The aim of the study was to evaluate the effectiveness of a diagnostic and therapeutic algorithm for gastroesophageal reflux disease complicated by Barrett's esophagus in 46 patients. MATERIALS AND METHODS: A diagnostic and therapeutic algorithm for complicated GERD was developed. To describe the changes in the esophagus with reflux esophagitis, the Los Angeles classification was used. Intestinal metaplasia of the epithelium in the lower third of the esophagus was assessed using videoendoscopy, chromoscopy, and biopsy...
August 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28904245/gallstone-ileus-in-an-ederly-patient-case-report
#6
Antonino Tornambè, Giuseppe Tornambè
AIM: To report an another case of gallstone ileus in ederly patient that was treated with simple enterolithotomy. MATERIAL OF STUDY: We report a case of 84 years old female that was admitted with intestinal obstruction. A CT scan suggested small bowel obstruction secondary to gallstone ileus. In relation to the overall clinical condition, we decided to perform a simple enterolithotomy. DISCUSSION: The first case of a cholecysto intestinal fistula with a gallstone within the gastro intestinal tract was described n 1654 by, Thomas Bartholin in a necropsy study...
September 4, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28890764/lactococcus-lactis-strain-a5-producing-nisin-like-bacteriocin-active-against-gram-positive-and-negative-bacteria
#7
Nur Shazana Azhar, Noor Hasniza Md Zin, Tengku Haziyamin Tengku Abdul Hamid
In this study, a Lactic acid bacteria (LAB) strain was isolated on MRS medium from gastro-intestinal tissues of Broadhead catfish (Clarias macrocephalus). Out of 50 isolates, 25 isolates were found to be positive on lactose utilisation test and were identified to be gram positive cocci. Using disc diffusion methods, one out of 22 isolates, i.e., a strain A5 demonstrated inhibitions against three indicator organisms; Bacillus cereus, Staphylococcus aureus and Salmonella thyphimurium. Partial 16S rDNA sequencing identified isolate A5 as a member of Lactococcus lactis, with 100% DNA homology...
July 2017: Tropical Life Sciences Research
https://www.readbyqxmd.com/read/28885095/spatial-rectal-dose-volume-metrics-predict-patient-reported-gastro-intestinal-symptoms-after-radiotherapy-for-prostate-cancer
#8
Oscar Casares-Magaz, Ludvig Paul Muren, Vitali Moiseenko, Stine E Petersen, Niclas Johan Pettersson, Morten Høyer, Joseph O Deasy, Maria Thor
BACKGROUND: Gastro-intestinal (GI) toxicity after radiotherapy (RT) for prostate cancer reduces patient's quality of life. In this study, we explored associations between spatial rectal dose/volume metrics and patient-reported GI symptoms after RT for localized prostate cancer, and compared these with those of dose-surface/volume histogram (DSH/DVH) metrics. MATERIAL AND METHODS: Dose distributions and six GI symptoms (defecation urgency/emptying difficulties/fecal leakage, ≥Grade 2, median follow-up: 3...
September 8, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28882973/elevated-serum-aa-epa-ratio-as-a-predictor-of-skeletal-muscle-depletion-in-cachexic-patients-with-advanced-gastro-intestinal-cancers
#9
Moeko Kitagawa, Seiji Haji, Teruyoshi Amagai
BACKGROUND: In recent years, the number of cancer patients has increased. Cancer patients are prone to sarcopenia as a result of the decrease in muscle mass and muscle weakness which occurs in cancer cachexia. Attention has been given on the effects of fatty acid administration on cancer patients. MATERIALS AND METHODS: We conducted a retrospective chart-review study of consecutive patients with unresectable advanced GI cancer (stage IV) (n=46) receiving chemotherapy treatment in an outpatient or in-hospital setting between December 2012 and September 2015 at our Institution...
September 2017: In Vivo
https://www.readbyqxmd.com/read/28873730/probiotics-as-potential-alternative-biocontrol-agents-in-the-agriculture-and-food-industries-a-review
#10
REVIEW
Md Iqbal Hossain, Mohammad Sadekuzzaman, Sang-Do Ha
Pathogenic microorganisms are a potential threat to the agriculture and food industries. Food contamination can be happened in the production levels at any point in the chain by pathogenic microorganisms. Conventional methods, such as those involving antibiotics, disinfectants, and physical methods, are commonly used as microbial control strategies. Owing to the limitations of these methods, such as emergence of resistance, low effectiveness, high cost, and detrimental effects on food, health, and the environment, many countries have adopted laws and regulations restricting their use...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873645/mechanisms-and-kinetics-of-heme-iron-nitrosylation-in-an-in-vitro-gastro-intestinal-model
#11
Diane de La Pomélie, Véronique Santé-Lhoutellier, Philippe Gatellier
Fresh red meat and cured meat consumption increases the risk of gastro-intestinal cancers and it is strongly suspected that nitrosylheme is implicated by stimulating the endogenous production of mutagenic aldehydes and N-nitroso compounds. To investigate the extent of endogenous heme iron nitrosylation an experimental in vitro model that mimics the physicochemical conditions of the gastro-intestinal tract was used in association with a mathematical model of chemical reaction kinetics. The combined effect of pH (from 7...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28866670/clinical-outcome-for-congenital-diaphragmatic-hernia-at-the-age-of-1-year-in-the-era-of-fetal-intervention
#12
Eva Van Ginderdeuren, Karel Allegaert, Herbert Decaluwe, Jan Deprest, Anne Debeer, Marijke Proesmans
BACKGROUND: Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlusion (FETO), a promising new technique to increase survival chances for severe cases, the outcomes are even less documented. AIM: To prospectively document the clinical outcome of CDH at 1 year including FETO-treated infants in relation to ante- and postnatal variables...
September 2, 2017: Neonatology
https://www.readbyqxmd.com/read/28851249/bacterial-pneumonia-in-patients-with-liver-cirrhosis-with-or-without-hiv-co-infection-a-possible-definition-of-antibiotic-prophylaxis-associated-pneumonia-apap
#13
Gianluca Cuomo, Giuseppina Brancaccio, Gianfranca Stornaiuolo, Daniela Manno, Giuseppe L Gaeta, Cristina Mussini, Massimo Puoti, Giovanni B Gaeta
Introducion: Bacterial infections frequently complicate liver cirrhosis. The aim of this study was to identify risk factors and clinical impact of bacterial pneumonia in patients with cirrhosis. MATERIALS AND METHODS: Bacterial infection prevalence study: consecutive patients with cirrhosis were enroled over a six-month period in 13 Italian centres. Pneumonia and other infections were diagnosed by standard methods. Pneumonia study: cirrhotic patients with pneumonia were enroled for an additional six-month period and HIV-positive patients were included...
August 29, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28848249/an-overview-of-parasitic-infections-of-the-gastro-intestinal-tract-in-developed-countries-affecting-immunocompromised-individuals
#14
REVIEW
Zohaib A Siddiqui
In both developed and developing countries, parasitic infections continue to be a frequent cause of mortality and morbidity. Due to the globalization of the world, doctors must be fully prepared to deal with a plethora of parasitic infections. More commonly the gastrointestinal (GI) tract is infected and in developed countries protozoans are more likely to be the cause of infection compared to helminths. These GI protozoa are progressively becoming recognized as important pathogens in patients that are immunocompromised...
September 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28847398/sequential-transformation-of-the-structural-and-thermodynamic-parameters-of-the-complex-particles-combining-covalent-conjugate-sodium-caseinate-maltodextrin-with-polyunsaturated-lipids-stabilized-by-a-plant-antioxidant-in-the-simulated-gastro-intestinal-conditions
#15
Anna S Antipova, Darya V Zelikina, Elena A Shumilina, Maria G Semenova
The present work is focused on the structural transformation of the complexes, formed between covalent conjugate (sodium caseinate + maltodextrin) and an equimass mixture of the polyunsaturated lipids (PULs): (soy phosphatidylcholine + triglycerides of flaxseed oil) stabilized by a plant antioxidant (an essential oil of clove buds), in the simulated conditions of the gastrointestinal tract. The conjugate was used here as a food-grade delivery vehicle for the PULs. The release of these PULs at each stage of the simulated digestion was estimated...
October 2016: Food Research International
https://www.readbyqxmd.com/read/28839371/berberine-depresses-contraction-of-smooth-muscle-via-inhibiting-myosin-light-chain-kinase
#16
Zhili Xu, Mingbo Zhang, Deqiang Dou, Xiaojun Tao, Tingguo Kang
BACKGROUND: Berberine is a natural isoquinoline alkaloid possessing various pharmacological effects, particularly apparent in the treatment of diarrhea, but the underlying mechanism remains unclear. Smooth muscle myosin light-chain kinase (MLCK) plays a crucial role in the smooth muscle relaxation-contraction events, and it is well known that berberine can effectively depress the contraction of smooth muscle. Hence, whether berberine could inhibit MLCK and then depress the smooth muscle contractility might be researched...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28836997/ethnomedicinal-plants-used-by-local-inhabitants-of-jakholi-block-rudraprayag-district-western-himalaya-india
#17
Ankit Singh, Mohan C Nautiyal, Ripu M Kunwar, Rainer W Bussmann
BACKGROUND: Ethnomedicinal knowledge of the Indian Himalayas is very interesting because of the wide range of medicinal plants used in traditional medical practice. However, there is a danger of knowledge being lost because the knowledge sharing is very limited and passed on orally. The present study is the first ethnomedicinal study in Jakholi area of Rudraprayag district of Northwestern India. The aim of present study was to identify traditional medicinal plants used by the inhabitants to treat different ailments and document the associated knowledge of these medicinal plants...
August 24, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28834636/intraosseous-rosai-dorfman-disease-diagnosed-by-touch-imprint-cytology-evaluation-a-case-series
#18
Avani A Pendse, Sara E Wobker, Kevin G Greene, Scott V Smith, Robert J Esther, Leslie G Dodd
Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease (RDD) is a rare benign disorder that primarily affects the lymph nodes. Localized lymphadenopathy is the most common clinical manifestation of this disorder. However, RDD has been described in several extra-nodal sites including the head and neck region, soft tissue, skin, upper respiratory tract, gastro-intestinal tract and central nervous system (CNS). Involvement of the bone is considered very rare, occurring in less than 10% patients...
August 23, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28830806/an-outbreak-of-clostridium-difficile-infections-due-to-a-new-pcr-ribotype-826-epidemiological-and-microbiological-analyses
#19
Monique J T Crobach, Anne F Voor In 't Holt, Cornelis W Knetsch, Sofie M van Dorp, Willeke Bras, Celine Harmanus, Ed J Kuijper, Margreet C Vos
OBJECTIVES: The aim was to investigate an unusual outbreak of 5 patients with in total 8 episodes of a Clostridium difficile infection (CDI) on a gastro intestinal surgical ward of a Dutch tertiary care university affiliated hospital. METHODS: Clinical case investigations and laboratory analyses were performed. Laboratory analyses included PCR ribotyping, MLVA typing, toxinotyping, antimicrobial susceptibility testing and whole genome sequencing. RESULTS: The outbreak was associated with recurrent and severe disease in 2 out of 5 patients...
August 19, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28819089/follow-up-practices-of-surgeons-and-medical-oncologists-in-australia-and-new-zealand-following-resection-of-esophagogastric-cancers
#20
Tim Chew, Tim Bright, Timothy J Price, David I Watson, Peter G Devitt
PURPOSE: Follow-up practices for patients who have undergone surgical resection of esophagogastric malignancies are variable and poorly documented. To better understand practice, a questionnaire was used to survey surgeons and medical oncologists to determine whether any consensus exists. METHODS: An opt-in online questionnaire was sent to esophagogastric surgeons and medical oncologists via the membership lists for the Australian and New Zealand Gastric and Oesophageal Surgery Association (ANZGOSA), the Australian Gastro-Intestinal Trials Groups (AGITG), and the Medical Oncology Group of Australia (MOGA)...
August 15, 2017: Annals of Thoracic and Cardiovascular Surgery
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