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Keywords Accelerometry and parkinson's ...

Accelerometry and parkinson's disease

https://read.qxmd.com/read/35961132/harmonic-ratio-is-the-most-responsive-trunk-acceleration-derived-gait-index-to-rehabilitation-in-people-with-parkinson-s-disease-at-moderate-disease-stages
#21
JOURNAL ARTICLE
Stefano Filippo Castiglia, Dante Trabassi, Roberto De Icco, Antonella Tatarelli, Micol Avenali, Michele Corrado, Valentina Grillo, Gianluca Coppola, Alessandro Denaro, Cristina Tassorelli, Mariano Serrao
BACKGROUND: Harmonic ratios (HRs), recurrence quantification analysis in the antero-posterior direction (RQAdetAP ), and stride length coefficient of variation (CV) have recently been shown to characterize gait abnormalities and fall risk in people with Parkinson's disease (pwPD) at moderate disease stages. RESEARCH QUESTION: This study aimed to i) assess the internal and external responsiveness to rehabilitation of HR, RQAdetAP , and CV, ii) identify the baseline predictors of normalization of the gait stability indexes, and iii) investigate the correlations between the gait indexes modifications (∆) and clinical and kinematic ∆s in pwPD at Hoehn and Yahr disease staging classification 3...
July 21, 2022: Gait & Posture
https://read.qxmd.com/read/35836147/multiple-n-of-1-trials-to-investigate-hypoxia-therapy-in-parkinson-s-disease-study-rationale-and-protocol
#22
JOURNAL ARTICLE
Jules M Janssen Daalen, Marjan J Meinders, Federica Giardina, Kit C B Roes, Bas C Stunnenberg, Soania Mathur, Philip N Ainslie, Dick H J Thijssen, Bastiaan R Bloem
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disease, for which no disease-modifying therapies exist. Preclinical and clinical evidence suggest that hypoxia-based therapy might have short- and long-term benefits in PD. We present the contours of the first study to assess the safety, feasibility and physiological and symptomatic impact of hypoxia-based therapy in individuals with PD. METHODS/DESIGN: In 20 individuals with PD, we will investigate the safety, tolerability and short-term symptomatic efficacy of continuous and intermittent hypoxia using individual, double-blind, randomized placebo-controlled N-of-1 trials...
July 14, 2022: BMC Neurology
https://read.qxmd.com/read/35783129/accuracy-of-step-count-estimations-in-parkinson-s-disease-can-be-predicted-using-ambulatory-monitoring
#23
JOURNAL ARTICLE
Navid Shokouhi, Hamid Khodakarami, Chathurini Fernando, Sarah Osborn, Malcolm Horne
Objectives: There are concerns regarding the accuracy of step count in Parkinson's disease (PD) when wearable sensors are used. In this study, it was predicted that providing the normal rhythmicity of walking was maintained, the autocorrelation function used to measure step count would provide relatively low errors in step count. Materials and Methods: A total of 21 normal walkers (10 without PD) and 27 abnormal walkers were videoed while wearing a sensor [Parkinson's KinetiGraph (PKG)]...
2022: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/35647517/differentiation-of-parkinson-s-disease-tremor-and-essential-tremor-based-on-a-novel-hand-posture
#24
JOURNAL ARTICLE
Sujitha Mahendran, Oliver Bichsel, Roger Gassert, Christian R Baumann, Lukas L Imbach, Daniel Waldvogel
Background: Tremor is one of the most common movement disorders but the correct diagnosis of tremor disorders, especially the differentiation between Parkinson's disease tremor (PT) and essential tremor (ET) remains a challenge for clinicians. Method: We examined a novel hand position to distinguish PT from ET. We prospectively collected accelerometric tremor data in 14 ET patients and 14 PT patients with arms and hands fully stretched against arms stretched and hands relaxed, i...
2022: Clinical parkinsonism & related disorders
https://read.qxmd.com/read/35566401/intraoperative-quantification-of-mds-updrs-tremor-measurements-using-3d-accelerometry-a-pilot-study
#25
JOURNAL ARTICLE
Annemarie Smid, Jan Willem J Elting, J Marc C van Dijk, Bert Otten, D L Marinus Oterdoom, Katalin Tamasi, Tjitske Heida, Teus van Laar, Gea Drost
The most frequently used method for evaluating tremor in Parkinson's disease (PD) is currently the internationally standardized Movement Disorder Society-Unified PD Rating Scale (MDS-UPDRS). However, the MDS-UPDRS is associated with limitations, such as its inherent subjectivity and reliance on experienced raters. Objective motor measurements using accelerometry may overcome the shortcomings of visually scored scales. Therefore, the current study focuses on translating the MDS-UPDRS tremor tests into an objective scoring method using 3D accelerometry...
April 19, 2022: Journal of Clinical Medicine
https://read.qxmd.com/read/34960379/an-automatic-gait-analysis-pipeline-for-wearable-sensors-a-pilot-study-in-parkinson-s-disease
#26
JOURNAL ARTICLE
Luis R Peraza, Kirsi M Kinnunen, Roisin McNaney, Ian J Craddock, Alan L Whone, Catherine Morgan, Richard Joules, Robin Wolz
The use of wearable sensors allows continuous recordings of physical activity from participants in free-living or at-home clinical studies. The large amount of data collected demands automatic analysis pipelines to extract gait parameters that can be used as clinical endpoints. We introduce a deep learning-based automatic pipeline for wearables that processes tri-axial accelerometry data and extracts gait events-bout segmentation, initial contact (IC), and final contact (FC)-from a single sensor located at either the lower back (near L5), shin or wrist...
December 11, 2021: Sensors
https://read.qxmd.com/read/34960353/wearable-gps-and-accelerometer-technologies-for-monitoring-mobility-and-physical-activity-in-neurodegenerative-disorders-a-systematic-review
#27
REVIEW
Mícheál Ó Breasail, Bijetri Biswas, Matthew D Smith, Md Khadimul A Mazhar, Emma Tenison, Anisha Cullen, Fiona E Lithander, Anne Roudaut, Emily J Henderson
Neurodegenerative disorders (NDDs) constitute an increasing global burden and can significantly impair an individual's mobility, physical activity (PA), and independence. Remote monitoring has been difficult without relying on diaries/questionnaires which are more challenging for people with dementia to complete. Wearable global positioning system (GPS) sensors and accelerometers present a cost-effective and noninvasive way to passively monitor mobility and PA. In addition, changes in sensor-derived outcomes (such as walking behaviour, sedentary, and active activity) may serve as potential biomarkers of disease onset, progression, and response to treatment...
December 10, 2021: Sensors
https://read.qxmd.com/read/34924785/spectral-analysis-of-lithium-tremor
#28
JOURNAL ARTICLE
Gül Yalçin Çakmakli, Yavuz Ayhan, M Kâzım Yazici, Mehmet Demirci, Gürdal Şahin
Introduction: Lithium has proven efficacy in bipolar affective disorder (BAD) but induces tremor as a side effect in a quarter of patients. Lithium tremor (LT) shares some clinical characteristics of essential tremor (ET) and Parkinson's disease tremor (PT), which might cause difficulties in differential diagnosis. Furthermore, current knowledge of LT is lacking detailed electrophysiological characterization. Here, we present detailed spectral attributes of accelerometric tremor recordings as a diagnostic tool for LT...
2021: Noro Psikiyatri Arsivi
https://read.qxmd.com/read/34892788/triaxial-accelerometry-wireless-system-for-characterization-of-parkinsonian-tremor
#29
JOURNAL ARTICLE
Andres Carmona-Almazan, Guadalupe Dorantes-Mendez, Jose F Rodriguez-Arellano, Aldo R Mejia-Rodriguez
Parkinsonian Tremor (PT) is the most common symptom of Parkinson's disease. Its early detection plays an important role in the diagnosis of the disease as it is often mistaken for another type of tremor, called Essential Tremor (ET). Accelerometry analysis has proven to be a trustworthy method for determining the frequency, amplitude, and occurrence of tremor. In addition, the use of portable and wearable sensors has increased due to the rapid growth of Internet of Things (IoT) technology, allowing data to be collected, processed, stored, and transmitted...
November 2021: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/34883886/rapid-dynamic-naturalistic-monitoring-of-bradykinesia-in-parkinson-s-disease-using-a-wrist-worn-accelerometer
#30
JOURNAL ARTICLE
Jeroen G V Habets, Christian Herff, Pieter L Kubben, Mark L Kuijf, Yasin Temel, Luc J W Evers, Bastiaan R Bloem, Philip A Starr, Ro'ee Gilron, Simon Little
Motor fluctuations in Parkinson's disease are characterized by unpredictability in the timing and duration of dopaminergic therapeutic benefits on symptoms, including bradykinesia and rigidity. These fluctuations significantly impair the quality of life of many Parkinson's patients. However, current clinical evaluation tools are not designed for the continuous, naturalistic (real-world) symptom monitoring needed to optimize clinical therapy to treat fluctuations. Although commercially available wearable motor monitoring, used over multiple days, can augment neurological decision making, the feasibility of rapid and dynamic detection of motor fluctuations is unclear...
November 26, 2021: Sensors
https://read.qxmd.com/read/34853806/accuracy-of-smartphone-video-for-contactless-measurement-of-hand-tremor-frequency
#31
JOURNAL ARTICLE
Stefan Williams, Hui Fang, Samuel D Relton, David C Wong, Taimour Alam, Jane E Alty
Background: Computer vision can measure movement from video without the time and access limitations of hospital accelerometry/electromyography or the requirement to hold or strap a smartphone accelerometer. Objective: To compare computer vision measurement of hand tremor frequency from smartphone video with a gold standard measure accelerometer. Methods: A total of 37 smartphone videos of hands, at rest and in posture, were recorded from 15 participants with tremor diagnoses (9 Parkinson's disease, 5 essential tremor, 1 functional tremor)...
January 2021: Movement Disorders Clinical Practice
https://read.qxmd.com/read/34809610/diagnosis-of-orthostatic-tremor-using-smartphone-accelerometry
#32
JOURNAL ARTICLE
Nicholas E Calvo, Joseph M Ferrara
BACKGROUND: Primary orthostatic tremor (OT) is a rare movement disorder characterized by a 13-18 Hz leg tremor, which arises when standing and is relieved by walking/sitting. Those affected generally do not fall, but experience fear of falling, lessened by ambulation. Because of its low amplitude, the tremor is not readily visible, and diagnosis requires confirmation with surface electromyography (sEMG). Recently, applications using the accelerometer feature of smartphones have been used to detect and quantify tremors, including OT, though the accuracy of smartphone accelerometry (SPA) in diagnosing OT is unknown...
November 22, 2021: BMC Neurology
https://read.qxmd.com/read/34749075/wrist-based-accelerometer-cut-points-for-quantifying-moderate-to-vigorous-intensity-physical-activity-in-parkinson-s-disease
#33
JOURNAL ARTICLE
Brenda Jeng, Katie L J Cederberg, Byron Lai, Jeffer E Sasaki, Marcas M Bamman, Robert W Motl
BACKGROUND: Persons with Parkinson's disease (PD) participate in low levels of physical activity. This has prompted interest in developing interventions targeting physical activity behavior in PD. However, the current cut-points to quantify moderate-to-vigorous physical activity (MVPA) developed for PD have been derived from a single, vertical axis using hip-worn accelerometers, and this cut-point may not be applicable for wrist-worn devices. Wrist-worn devices might improve accessibility and compliance with physical activity monitoring in PD...
October 25, 2021: Gait & Posture
https://read.qxmd.com/read/34320441/evidence-of-slow-and-variable-choice-stepping-reaction-time-in-cancer-survivors-with-chemotherapy-induced-peripheral-neuropathy
#34
JOURNAL ARTICLE
J C Menant, D Goldstein, K Au, T Trinh, K S van Schooten, J M McCrary, C A Harris, B C Forster, S B Park
BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is reported to affect up to 70 % of cancer survivors. Despite evidence that CIPN-related impairments often translate into balance and mobility deficits, the effects on stepping and quality of gait, well-documented risk factors for falls, are unclear. AIMS: (i) Establish choice-stepping reaction time (CSRT) performance in survivors with CIPN compared to young and older healthy controls and people with Parkinson's disease; (ii) document walking stability; (iii) investigate relationships between stepping and gait data to objective and patient-reported outcomes...
September 2021: Gait & Posture
https://read.qxmd.com/read/34171566/accuracy-and-precision-of-wrist-worn-actigraphy-for-measuring-steps-taken-during-over-ground-and-treadmill-walking-in-adults-with-parkinson-s-disease
#35
JOURNAL ARTICLE
Katie L J Cederberg, Brenda Jeng, Jeffer E Sasaki, Byron Lai, Marcas Bamman, Robert W Motl
INTRODUCTION: Step counts represent a straight-forward method of measuring physical activity in adults with Parkinson's disease (PD). The present study examined the absolute and relative accuracy and precision of a wrist-worn research-grade accelerometer (i.e., ActiGraph GT3X+) for measuring step counts during over-ground and treadmill walking in adults with PD and controls without PD. METHODS: Participants (PD: n = 29; controls: n = 31) wore two ActiGraph GT3X + accelerometers, one on each wrist, and completed an over-ground walking bout followed by a treadmill walking bout at the same speed...
July 2021: Parkinsonism & related Disorders
https://read.qxmd.com/read/34063468/ability-of-a-set-of-trunk-inertial-indexes-of-gait-to-identify-gait-instability-and-recurrent-fallers-in-parkinson-s-disease
#36
JOURNAL ARTICLE
Stefano Filippo Castiglia, Antonella Tatarelli, Dante Trabassi, Roberto De Icco, Valentina Grillo, Alberto Ranavolo, Tiwana Varrecchia, Fabrizio Magnifica, Davide Di Lenola, Gianluca Coppola, Donatella Ferrari, Alessandro Denaro, Cristina Tassorelli, Mariano Serrao
The aims of this study were to assess the ability of 16 gait indices to identify gait instability and recurrent fallers in persons with Parkinson's disease (pwPD), regardless of age and gait speed, and to investigate their correlation with clinical and kinematic variables. The trunk acceleration patterns were acquired during the gait of 55 pwPD and 55 age-and-speed matched healthy subjects using an inertial measurement unit. We calculated the harmonic ratios (HR), percent recurrence, and percent determinism (RQAdet), coefficient of variation, normalized jerk score, and the largest Lyapunov exponent for each participant...
May 15, 2021: Sensors
https://read.qxmd.com/read/33799420/detecting-parkinson-s-disease-from-wrist-worn-accelerometry-in-the-u-k-biobank
#37
JOURNAL ARTICLE
James R Williamson, Brian Telfer, Riley Mullany, Karl E Friedl
Parkinson's disease (PD) is a chronic movement disorder that produces a variety of characteristic movement abnormalities. The ubiquity of wrist-worn accelerometry suggests a possible sensor modality for early detection of PD symptoms and subsequent tracking of PD symptom severity. As an initial proof of concept for this technological approach, we analyzed the U.K. Biobank data set, consisting of one week of wrist-worn accelerometry from a population with a PD primary diagnosis and an age-matched healthy control population...
March 14, 2021: Sensors
https://read.qxmd.com/read/33799200/rest-tremor-correlates-with-reduced-contralateral-striatal-dopamine-transporter-binding-in-parkinson-s-disease
#38
JOURNAL ARTICLE
Alessandro F Fois, Florence Cf Chang, Robert Barnett, Kevin London, Neil Mahant, Ainhi Ha, Zakiyah Aldaajani, Belinda Cruse, Hugo Morales-Briceno, Kit Kwan Ma, David Farlow, Victor Sc Fung
INTRODUCTION: In vivo dopamine transporter imaging is a useful tool for distinguishing nigrostriatal pathologies (e.g. Parkinson's disease) from other causes of tremor. However, while many of the motoric features of Parkinson's disease (e.g. bradykinesia, rigidity, hypomimia) correlate well with reduced striatal dopamine transporter binding, the same relationship has not been demonstrated for tremor. We investigated the relationship between striatal dopamine transporter binding and quantitative measures of tremor...
April 2021: Parkinsonism & related Disorders
https://read.qxmd.com/read/33790751/a-neuromotor-to-acoustical-jaw-tongue-projection-model-with-application-in-parkinson-s-disease-hypokinetic-dysarthria
#39
JOURNAL ARTICLE
Andrés Gómez, Pedro Gómez, Daniel Palacios, Victoria Rodellar, Víctor Nieto, Agustín Álvarez, Athanasios Tsanas
Aim: The present work proposes the study of the neuromotor activity of the masseter-jaw-tongue articulation during diadochokinetic exercising to establish functional statistical relationships between surface Electromyography (sEMG), 3D Accelerometry (3DAcc), and acoustic features extracted from the speech signal, with the aim of characterizing Hypokinetic Dysarthria (HD). A database of multi-trait signals of recordings from an age-matched control and PD participants are used in the experimental study...
2021: Frontiers in Human Neuroscience
https://read.qxmd.com/read/33722243/severity-of-parkinsonism-associated-with-environmental-manganese-exposure
#40
JOURNAL ARTICLE
Brad A Racette, Gill Nelson, Wendy W Dlamini, Pradeep Prathibha, Jay R Turner, Mwiza Ushe, Harvey Checkoway, Lianne Sheppard, Susan Searles Nielsen
BACKGROUND: Exposure to occupational manganese (Mn) is associated with neurotoxic brain injury, manifesting primarily as parkinsonism. The association between environmental Mn exposure and parkinsonism is unclear. To characterize the association between environmental Mn exposure and parkinsonism, we performed population-based sampling of residents older than 40 in Meyerton, South Africa (N = 621) in residential settlements adjacent to a large Mn smelter and in a comparable non-exposed settlement in Ethembalethu, South Africa (N = 95) in 2016-2020...
March 15, 2021: Environmental Health
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