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Balance and parkinson's disease

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https://www.readbyqxmd.com/read/28210066/effects-of-interactive-metronome-training-on-postural-stability-and-upper-extremity-function-in-parkinson-s-disease-a-case-study
#1
Arim Kim, Hye-Sun Lee, Chiang-Soon Song
[Purpose] The purpose of this study was to examine the effects of interactive metronome training on the postural stability and upper extremity function of an individual with Parkinson's disease. [Subject and Methods] The participant of this case study was a 75-year-old female with Parkinson's disease diagnosed 7 years prior. This study was a single-subject research with an A-B-A design. She received IM training during the treatment phase (B phase) for 40 minutes per session. She was assessed pretest and posttest using the Berg balance scale and Wolf motor function test, and at baseline and the treatment phase using the measured box-and-block test and a Tetrax system...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28204768/dopa-responsive-balance-changes-depend-on-use-of-internal-versus-external-attentional-focus-in-parkinson-disease
#2
Eric N Beck, Quincy J Almeida
No abstract text is available yet for this article.
February 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28190675/effectiveness-of-exergaming-in-improving-functional-balance-fatigue-and-quality-of-life-in-parkinson-s-disease-a-pilot-randomized-controlled-trial
#3
REVIEW
Camila Gemin Ribas, Letícia Alves da Silva, Marina Ribas Corrêa, Hélio Ghizone Teive, Silvia Valderramas
: Although motor symptoms in Parkinson's disease (PD) are well established, few studies have described the effects of exergaming on the clinical and functional outcomes of PD. OBJECTIVES: To analyze the effectiveness of exergaming in improving functional balance, fatigue, functional exercise capacity and quality of life in PD. METHODS: The study population consisted of 20 patients (12 males and 8 females) aged 61 ± 9.11 years allocated into two groups: an exergaming group (EGG) (n = 10) and a conventional exercise, or control, group (CG) (n = 10)...
February 7, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28173775/evaluation-and-implementation-of-highly-challenging-balance-training-in-clinical-practice-for-people-with-parkinson-s-disease-protocol-for-the-hibalance-effectiveness-implementation-trial
#4
Breiffni Leavy, Lydia Kwak, Maria Hagströmer, Erika Franzén
BACKGROUND: If people with progressive neurological diseases are to avail of evidence-based rehabilitation, programs found effective in randomized controlled trials (RCT's) must firstly be adapted and tested in clinical effectiveness studies as a means of strengthening their evidence base. This paper describes the protocol for an effectiveness-implementation trial that will assess the clinical effectiveness of a highly challenging balance training program (the HiBalance program) for people with mild-moderate Parkinson's disease (PD) while simultaneously collecting data concerning the way in which the program is implemented...
February 7, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28167167/nintendo-wii-fit-for-balance-rehabilitation-in-patients-with-parkinson-s-disease-a-comparative-study
#5
Stefano Negrini, Luciano Bissolotti, Alessandro Ferraris, Fulvia Noro, Mark D Bishop, Jorge Hugo Villafañe
BACKGROUND: Impaired postural stability places individuals with Parkinson's disease (PD) at an increased risk for falls. OBJECTIVE: We evaluated the effectiveness of 10 vs. 15 sessions of Nintendo Wii Fit for balance recovery for outpatients PD. METHODS: Twenty-seven patients, 48.1% female (66 ± 8 years), with PD. Patients with PD were consecutively assigned to one of two groups receiving either 10 or 15 sessions (low dose or high dose group, respectively) with Nintendo Wii Fit in recovering balancing ability...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28163919/therapeutic-effects-of-intensive-inpatient-rehabilitation-in-advanced-parkinson-s-disease
#6
Yumiko Kaseda, Junko Ikeda, Katsunobu Sugihara, Takemori Yamawaki, Tatsuo Kohriyama, Masayasu Matsumoto
BACKGROUND: The importance of rehabilitation therapy in Parkinson's disease is well recognized. However, the effects of an inpatient rehabilitation program for advanced Parkinson's disease have not been fully investigated. AIM: To assess the effects of intensive inpatient rehabilitation. METHODS: We enrolled 31 patients (mean age 69.5 ± 9.4 years; mean disease duration 8.8 ± 6.4 years) with advanced Parkinson's disease, without severe cognitive impairment...
January 2017: Neurology and Clinical Neuroscience
https://www.readbyqxmd.com/read/28158197/rehabilitation-in-progressive-supranuclear-palsy-effectiveness-of-two-multidisciplinary-treatments
#7
Ilaria Clerici, Davide Ferrazzoli, Roberto Maestri, Fabiola Bossio, Ilaria Zivi, Margherita Canesi, Gianni Pezzoli, Giuseppe Frazzitta
BACKGROUND: to date, there are no medical or surgical treatments for progressive supranuclear palsy (PSP). It is possible to speculate that patients with PSP could benefit from rehabilitative treatments designed for Parkinson's disease, including the use of robot-assisted walking training. OBJECTIVE: to evaluate whether the use of the robotic device Lokomat® is superior in PSP patients to the use of treadmill with visual cues and auditory feedbacks (treadmill-plus) in the context of an aerobic, multidisciplinary, intensive, motor-cognitive and goal-based rehabilitation treatment (MIRT) conceived for Parkinsonian patients...
2017: PloS One
https://www.readbyqxmd.com/read/28143463/monitoring-training-activity-during-gait-related-balance-exercise-in-individuals-with-parkinson-s-disease-a-proof-of-concept-study
#8
David Conradsson, Håkan Nero, Niklas Löfgren, Maria Hagströmer, Erika Franzén
BACKGROUND: Despite the benefits of balance exercise in clinical populations, balance training programs tend to be poorly described, which in turn makes it difficult to evaluate important training components and compare between programs. However, the use of wearable sensors may have the potential to monitor certain elements of balance training. Therefore, this study aimed to investigate the feasibility of using wearable sensors to provide objective indicators of the levels and progression of training activity during gait-related balance exercise in individuals with Parkinson's disease...
January 31, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28137358/distinct-mechanisms-mediate-speed-accuracy-adjustments-in-cortico-subthalamic-networks
#9
Damian M Herz, Huiling Tan, John-Stuart Brittain, Petra Fischer, Binith Cheeran, Alexander L Green, James FitzGerald, Tipu Z Aziz, Keyoumars Ashkan, Simon Little, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Rafal Bogacz, Peter Brown
Optimal decision-making requires balancing fast but error-prone and more accurate but slower decisions through adjustments of decision thresholds. Here, we demonstrate two distinct correlates of such speed-accuracy adjustments by recording subthalamic nucleus (STN) activity and electroencephalography in 11 Parkinson's disease patients during a perceptual decision-making task; STN low-frequency oscillatory (LFO) activity (2-8 Hz), coupled to activity at prefrontal electrode Fz, and STN beta activity (13-30 Hz) coupled to electrodes C3/C4 close to motor cortex...
January 31, 2017: ELife
https://www.readbyqxmd.com/read/28132574/robotic-assisted-gait-training-in-parkinson-s-disease-a-3-month-follow-up-randomized-clinical-trial
#10
Anna Furnari, Rocco Salvatore Calabrò, Maria Cristina De Cola, Marcello Bartolo, Alberto Castelli, Alessia Mapelli, Giampiero Buttacchio, Elena Farini, Placido Bramanti, Roberto Casale
PURPOSE: The aim of this study was to evaluate the efficacy of a Robotic-Assisted Gait Training (RAGT), together with a conventional exercise program (CEP), to improve PD ambulation, as compared to standard gait training. METHODS: Thirty-eight patients with mild PD stage (H&Y 2-2.5) were randomly assigned to an experimental group (EG) or a control group (CG). The 19 patients in EG received 30 min RAGT (using Lokomat device), whereas the 19 controls received a conventional gait training; both groups received 30 min of CEP...
January 28, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28130466/antisaccades-in-parkinson-disease-a-new-marker-of-postural-control
#11
Claire Ewenczyk, Salma Mesmoudi, Cécile Gallea, Marie-Laure Welter, Bertrand Gaymard, Adèle Demain, Lydia Yahia Cherif, Bertrand Degos, Habib Benali, Pierre Pouget, Cyril Poupon, Stéphane Lehericy, Sophie Rivaud-Péchoux, Marie Vidailhet
OBJECTIVE: To describe the relation between gaze and posture/gait control in Parkinson disease (PD) and to determine the role of the mesencephalic locomotor region (MLR) and cortex-MLR connection in saccadic behavior because this structure is a major area involved in both gait/postural control and gaze control networks. METHODS: We recruited 30 patients with PD with or without altered postural control and 25 age-matched healthy controls (HCs). We assessed gait, balance, and neuropsychological status and separately recorded gait initiation and eye movements (visually guided saccades and volitional antisaccades)...
January 27, 2017: Neurology
https://www.readbyqxmd.com/read/28104279/effect-of-inhibition-of-fatty-acid-amide-hydrolase-on-mptp-induced-dopaminergic-neuronal-damage
#12
J M Viveros-Paredes, R E Gonzalez-Castañeda, A Escalante-Castañeda, A R Tejeda-Martínez, F Castañeda-Achutiguí, M E Flores-Soto
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder characterised by balance problems, muscle rigidity, and slow movement due to low dopamine levels and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The endocannabinoid system is known to modulate the nigrostriatal pathway through endogenous ligands such as anandamide (AEA), which is hydrolysed by fatty acid amide hydrolase (FAAH). The purpose of this study was to increase AEA levels using FAAH inhibitor URB597 to evaluate the modulatory effect of AEA on dopaminergic neuronal death induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)...
January 16, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28097926/a-pilot-study-of-a-minimally-supervised-home-exercise-and-walking-program-for-people-with-parkinson-s-disease-in-jordan
#13
Hanan Khalil, Monica Busse, Lori Quinn, Mohammad Nazzal, Waleed Batyha, Shatha Alkhazaleh, Mahmoud A Alomari
AIM: This study aimed to evaluate the feasibility and cultural considerations of a minimally supervised, home-based exercise program in Jordan. METHODS: Quantitative and qualitative approaches were used. Thirty participants were randomly allocated to either an 8-week intervention group (n = 16), or a standard care group (n = 14). The intervention incorporated the home use of an exercise DVD, walking program and initial instructional sessions and weekly phone calls provided by a physiotherapist...
February 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28088064/improved-cognition-while-cycling-in-parkinson-s-disease-patients-and-healthy-adults
#14
Audrey A Hazamy, Lori J P Altmann, Elizabeth Stegemöller, Dawn Bowers, Hyo Keun Lee, Jonathan Wilson, Michael S Okun, Chris J Hass
Persons with Parkinson's disease (PD) are typically more susceptible than healthy adults to impaired performance when two tasks (dual task interference) are performed simultaneously. This limitation has by many experts been attributed to limitations in cognitive resources. Nearly all studies of dual task performance in PD employ walking or balance-based motor tasks, which are commonly impaired in PD. These tasks can be performed using a combination of one or two executive function tasks. The current study examined whether persons with PD would demonstrate greater dual task effects (DTEs) on cognition compared to healthy older adults (HOAs) during a concurrent cycling task...
January 11, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28067072/drug-target-identification-at-the-crossroad-of-neuronal-apoptosis-and-survival
#15
Barbara Maino, Simona Paparone, Cinzia Severini, Maria Teresa Ciotti, Velia D'agata, Pietro Calissano, Sebastiano Cavallaro
Inappropriate activation of apoptosis may contribute to neurodegeneration, a multifaceted process that results in various chronic disorders, including Alzheimer's and Parkinson's diseases. Several in vitro and in vivo studies demonstrated that neuronal apoptosis is a multi-pathway cell-death program that requires RNA synthesis. Thus, transcriptionally activated genes whose products induce cell death can be triggered by different stimuli and antagonized by neurotrophic factors. Systems biology is now unveiling the series of intracellular signaling pathways and key drug targets at the intersection of neuronal apoptosis and survival...
January 23, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28061431/effect-of-subthalamic-nucleus-deep-brain-stimulation-on-balance-in-parkinson-s-disease-a-static-posturographic-analysis
#16
Beatriz De la Casa-Fages, Fernando Alonso-Frech, Francisco Grandas
BACKGROUND: The effect of subthalamic deep brain stimulation on balance in Parkinson's disease remains unclear. OBJECTIVE: To evaluate the effect of subthalamic nucleus stimulation on balance in Parkinson's disease using posturography. METHODS: 16 patients (9 women) who underwent subthalamic deep brain stimulation [mean age 59.6 years (46-70); mean disease duration 15.6 years (7-25); mean duration of subthalamic stimulation 32.1 months (3...
December 29, 2016: Gait & Posture
https://www.readbyqxmd.com/read/28052701/potential-for-targeting-dopamine-darpp-32-signaling-in-neuropsychiatric-and-neurodegenerative-disorders
#17
Akinori Nishi, Takahide Shuto
Alterations in dopamine neurotransmission has been implicated in pathophysiology of neuropsychiatric and neurodegenerative disorders, and DARPP-32 plays a pivotal role in dopamine neurotransmission. DARPP-32 likely influences dopamine-mediated behaviors in animal models of neuropsychiatric and neurodegenerative disorders and therapeutic effects of pharmacological treatment. Areas covered: We will review animal studies on the biochemical and behavioral roles of DARPP-32 in drug addiction, schizophrenia and Parkinson's disease...
January 13, 2017: Expert Opinion on Therapeutic Targets
https://www.readbyqxmd.com/read/28049396/oxidative-stress-and-antioxidant-potential-of-one-hundred-medicinal-plants
#18
Waseem Hassan, Hamsa Noreen, Shakila Rehman, Shehnaz Gul, Mohammad Amjad Kamal, Jean Paul Kamdem, Bakht Zaman, Joao B T da Rocha
Reactive species are produced in biological system because of redox reactions. The imbalance in pro-oxidant and antioxidant homeostasis leads to the production of toxic reactive oxygen and nitrogen species like hydrogen peroxide, organic peroxides, hydroxyl radicals, superoxide anion and nitric oxide. Inactivation of metabolic enzymes, oxidation of biomolecules and cellular damage are some of the prominent characteristics of reactive species. Similarly, oxidative stress has been associated with more than one hundred (100) pathologies such as atherosclerosis, diabetes, cardiovascular diseases, pancreatic and liver diseases, joint disorders, cardiac fibrosis, acute respiratory distress syndrome, neurological diseases (amyotrophic lateral sclerosis, Huntington's disorder, Parkinson's disease and Alzheimer's disease), ageing and cancer etc...
January 2, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/28028942/effects-of-propofol-on-the-liver-oxidative-antioxidant-balance-in-a-rat-model-of-parkinson-s-disease
#19
Ewa B Romuk, Wioletta Szczurek, Przemysław G Nowak, Edyta Hudziec, Ewa Chwalińska, Ewa Birkner
BACKGROUND: Parkinson's disease is caused by the destruction of dopaminergic neurons in the substantia nigra of the midbrain. One of the possible factors involved in the pathogenesis of Parkinson's disease is impaired oxidativeantioxidative balance. OBJECTIVES: The present study aimed to evaluate selected parameters of the liver oxidative-antioxidative system in a Wistar rat model with Parkinson's disease treated with propofol. MATERIAL AND METHODS: Experiments were performed on 32 rats divided into 4 groups: 1 - control, 2 - Parkinson's disease, 3 - control with propofol, 4 - Parkinson's disease with propofol...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28027505/impairment-of-dynamic-thiol-disulphide-homeostasis-in-patients-with-idiopathic-parkinson-s-disease-and-its-relationship-with-clinical-stage-of-disease
#20
Gonul Vural, Sadiye Gumusyayla, Hesna Bektas, Orhan Deniz, Murat Alisik, Ozcan Erel
OBJECTIVE: The aim of this study was to investigate dynamic thiol-disulphide homeostasis in patients with idiopathic Parkinson's disease and to determine its relationship with the clinical stage as assessed by the modified Hoehn and Yahr scale. DESIGN AND METHODS: Fifty-two patients with Parkinson's disease (PD), diagnosed according to the United Kingdom Brain Bank Criteria for idiopathic PD, and 41 healthy individuals were included in the study. Clinical staging of patients was performed according to the Hoehn and Yahr scale...
February 2017: Clinical Neurology and Neurosurgery
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