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Balance and parkinson's disease

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https://www.readbyqxmd.com/read/27914023/reliability-and-validity-of-the-persian-translation-of-berg-balance-scale-in-parkinson-disease
#1
Arash Babaei-Ghazani, Hosein Mohammadi, Gholam Ali Shahidi, Seyed Amir Hasan Habibi, Bijan Forogh, Tannaz Ahadi, Bina Eftekharsadat
PURPOSE: Parkinson disease (PD) is one of the common causes of imbalance, and the balance assessment is necessary for treatment and rehabilitation of these patients. The Berg Balance Scale (BBS) has been the main instrument used to evaluate balance impairment. The purpose of this study is to investigate reliability and validity of the Persian translation of BBS in Parkinson disease. METHODS: One hundred PD patients (with mean age of 56.8 ± 15.13 years) were included...
December 2, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27912936/effects-of-mind-body-exercises-on-the-physiological-and-psychosocial-well-being-of-individuals-with-parkinson-s-disease-a-systematic-review-and-meta-analysis
#2
REVIEW
JoJo Yan Yan Kwok, Kai Chow Choi, Helen Yue Lai Chan
OBJECTIVES: The effects of mind-body exercises on individuals with chronic illnesses have attracted increasing attention. However, little effort had been made to systematically review the effects of these mind-body exercises on individuals with Parkinson's disease (PD). This review aimed to appraise the current evidence of the effects of mind-body exercises on the physiological and psychological outcomes for the PD population. DESIGN: Systematic review and meta-analysis of randomized controlled trials...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27901474/cerebellar-neurochemical-and-histopathological-changes-in-rat-model-of-parkinson-s-disease-induced-by-intrastriatal-injection-of-rotenone
#3
Yasser A Khadrawy, Iman M Mourad, Haitham S Mohammed, Neveen A Noor, Heba S Aboul Ezz
The aim of the present work was to investigate the neurochemical changes induced in the cerebellum of rat model of Parkinson's disease (PD). Rats were divided into two groups; control and rat model of PD induced by the intrastriatal injection of rotenone. As compared to control, a significant increase in the excitatory amino acid neurotransmitters; glutamate and aspartate together with a significant decrease in the inhibitory amino acids, GABA, glycine and taurine were observed in the cerebellum of rat model of PD...
November 30, 2016: General Physiology and Biophysics
https://www.readbyqxmd.com/read/27893997/psychometric-properties-of-dual-task-balance-and-walking-assessments-for-individuals-with-neurological-conditions-a-systematic-review
#4
REVIEW
Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BACKGROUND: The ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions...
November 15, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27893564/instrumented-test-of-sensory-integration-for-balance-a-validation-study
#5
Lynn Freeman, Geetanjali Gera, Fay B Horak, Mary T Blackinton, Mark Besch, Laurie King
BACKGROUND AND PURPOSE: Abnormal postural sway is associated with an increase in risk of falls but is difficult for clinicians to accurately quantify without access to laboratory equipment. Instrumenting clinical outcome measures using body-worn movement monitors is a low-cost alternative. This is the first study to compare the modified Clinical Test of Sensory Integration for Balance (i-mCTSIB) to the laboratory test of the Sensory Organization Test (SOT) with dynamic posturography in a group of participants with Parkinson's disease (PD) and subtle balance limitations...
November 23, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/27891159/effects-of-health-qigong-exercises-on-relieving-symptoms-of-parkinson-s-disease
#6
Xiao Lei Liu, Shihui Chen, Yongtai Wang
The purpose of this study was to investigate the effects of Health Qigong on the treatment and releasing symptoms of Parkinson's disease (PD). Fifty-four moderate PD patients (N = 54) were randomly divided into experimental and control groups. Twenty-eight PD patients were placed in the experimental group in which the prescribed medication plus Health Qigong exercise will be used as intervention. The other 26 PD patients as the control group were treated only with regular medication. Ten-week intervention had been conducted for the study, and participants completed the scheduled exercises 5 times per week for 60 minutes each time (10 minutes for warm-up, 40 minutes for the exercise, and 10 minutes for cooldown)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27889925/deletion-of-the-vesicular-acetylcholine-transporter-from-pedunculopontine-laterodorsal-tegmental-neurons-modifies-gait
#7
Helena Janickova, Kaie Rosborough, Mohammed Al-Onaizi, Ornela Kljakic, Monica S Guzman, Robert Gros, Marco A M Prado, Vania F Prado
Postural instability and gait disturbances, common disabilities in the elderly and frequently present in Parkinson's disease (PD), have been suggested to be related to dysfunctional cholinergic signalling in the brainstem. We investigated how long-term loss of cholinergic signalling from mesopontine nuclei influence motor behaviours. We selectively eliminated the vesicular acetylcholine transporter (VAChT) in pedunculopontine and laterodorsal tegmental nuclei cholinergic neurons to generate mice with selective mesopontine cholinergic deficiency (VAChT(E)(n1-Cre-flox/flox) )...
November 27, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27879959/balance-versus-resistance-training-on-postural-control-in-patients-with-parkinson-s-disease-a-randomised-controlled-trial
#8
Suhaila M Santos, Rubens A Da Silva, Marcelle B Terra, Isabela A Almeida, Lucio B De Melo, Henrique B Ferraz
BACKGROUND: Evidences have shown that physiotherapy programs may improve the balance of individuals with Parkinson's disease (PD); although it is not clear which specific exercise program is better. AIM: Compare the effectiveness of balance versus resistance training on postural control measures in PD patients. DESIGN: Randomised controlled trial. SETTING: The study was conducted in a physiotherapy outpatient clinic of a university hospital...
November 23, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27878585/motion-and-emotion-anxiety-axial-connections-in-parkinson-s-disease
#9
Rastislav Šumec, Irena Rektorová, Robert Jech, Kateřina Menšíková, Jan Roth, Evžen Růžička, Dana Sochorová, Ladislav Dušek, Petr Kaňovský, Ivan Rektor, Tomáš Pavlík, Pavel Filip, Martin Bareš
Anxiety is a serious and frequent complication in Parkinson's disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety-axial connections...
November 23, 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27878377/relationship-between-the-plasma-levels-of-neurodegenerative-proteins-and-motor-subtypes-of-parkinson-s-disease
#10
Jian Ding, Jiejin Zhang, Xixi Wang, Li Zhang, Siming Jiang, Yongsheng Yuan, Junyi Li, Lin Zhu, Kezhong Zhang
The aim of our study is to examine the plasma levels of the four kinds of neurodegenerative proteins in plasma: α-syn, T-tau, P-tau181, and Aβ-42 in Parkinson's disease (PD) and to evaluate the relationship between their plasma levels and PD motor subtypes. 84 patients with PD were enrolled in our study, and finally, 73 of them were classified into the tremor-dominant subtype (TD) and the postural instability gait difficulty subtype (PIGD). Their motor performance was evaluated by a series of clinical assessments: Freezing of Gait Questionnaire (FOGQ), Timed Up and Go (TUGs), Tinetti balance, and Tinetti gait...
November 22, 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27866086/the-role-of-postural-instability-gait-difficulty-and-fear-of-falling-in-predicting-falls-in-non-demented-older-adults
#11
Gilles Allali, Emmeline I Ayers, Roee Holtzer, Joe Verghese
INTRODUCTION: Postural instability/gait difficulty (PIGD) and fear of falling (FoF) frequently co-exist, but their individual predictive values for falls have not been compared in aging. This study aims to determine both independent and combined effect of PIGD and FoF to falls in older adults without dementia. METHODS: PIGD and other extrapyramidal signs were systematically assessed in 449 community-dwelling participants without Parkinson's disease (76.48±6.61 ys; 56...
November 13, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27856344/anxiety-provokes-balance-deficits-that-are-selectively-dopa-responsive-in-parkinson-s-disease
#12
Kaylena A Ehgoetz Martens, Shannon C Lefaivre, Eric N Beck, Rebecca Chow, Frederico Pieruccini-Faria, Colin G Ellard, Quincy J Almeida
Previous research has suggested that balance impairments may be linked to anxiety in PD, yet there is little empirical evidence to support this link in PD. This study aimed to evaluate the influence of anxiety on balance, and also examine whether dopaminergic treatment modulates the influence of anxiety on balance. Forty-two participants (10 high anxious PD [HA-PD]; 11 low anxious PD [LA-PD], 21 controls [HC]) performed 10 quiet standing trials on a force platform in two virtual environments: LOW threat; on a plank located on the ground; HIGH threat; on an elevated plank...
November 14, 2016: Neuroscience
https://www.readbyqxmd.com/read/27837003/medulla-oblongata-damage-and-cardiac-autonomic-dysfunction-in-parkinson-disease
#13
Nadya Pyatigorskaya, Marie Mongin, Romain Valabregue, Lydia Yahia-Cherif, Claire Ewenczyk, Cyril Poupon, Eden Debellemaniere, Marie Vidailhet, Isabelle Arnulf, Stephane Lehéricy
OBJECTIVE: To characterize medulla oblongata damage using diffusion tensor imaging (DTI) in Parkinson disease (PD) and correlate it with dysfunction of the cardiac sympathetic/vagal balance. METHODS: Fifty-two patients with PD and 24 healthy controls were included in the study. All participants underwent clinical examination and 3T MRI using 3D T1-weighted imaging and DTI. DTI metrics were calculated within manually drawn regions of interest. Heart rate variability was evaluated using spectral analysis of the R-R cardiac interval during REM and slow-wave sleep based on continuous overnight electrocardiographic monitoring...
November 11, 2016: Neurology
https://www.readbyqxmd.com/read/27830583/dynamin-related-protein-1-drp1-mediating-mitophagy-contributes-to-the-pathophysiology-of-nervous-system-diseases-and-brain-injury
#14
REVIEW
Qiong Wu, Cheng-Liang Luo, Lu-Yang Tao
As the main source of energy (celluar ATP) in eukaryotic cells, mitochondria are involved in cellular physiology and pathology. The balance of mitochondrial dynamic, fission and fusion regulated by quality control mechanisms, provides a guarantee for maintaining mitochondrial function, even celluar function. Worn out mitochondria would be removed through mitophagy which is regulated by autophagy related proteins and mitochondrial membrane proteins. Drp1, dynamic-related protein 1, is regarded as one of the most important proteins to evaluate mitochondrial fission mediating mitophagy in neurodegenerative diseases (eg...
November 10, 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/27825909/handgrip-strength-related-to-long-term-electromyography-application-for-assessing-functional-decline-in-parkinson-s-disease
#15
Gareth R Jones, Kaitlyn P Roland, Noelannah A Neubauer, Jennifer M Jakobi
OBJECTIVE: To determine which clinical measures of physical function (i.e. gait, balance, grip strength) best represent long-term EMG in persons with PD compared to healthy controls. DESIGN: Cross sectional study. SETTING: Community PARTICIPANTS: Twenty-three males and females with PD and 14 healthy controls, living independently at home, aged 50 years and older were recruited from the local community. INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: Measures of gait, balance and grip strength were completed and EMG was examined in biceps brachii, triceps brachii, vastus lateralis and biceps femoris during a 6...
November 5, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27814309/osteopathic-manipulation-as%C3%A2-a%C3%A2-complementary-approach-to%C3%A2-parkinson-s%C3%A2-disease-a%C3%A2-controlled-pilot%C3%A2-study
#16
Joanne DiFrancisco-Donoghue, Theresa Apoznanski, Kristen de Vries, Min-Kyung Jung, Jayme Mancini, Sheldon Yao
BACKGROUND: Osteopathic Manipulative Medicine (OMM) is a therapy of manual forces that is directed to improve function and homeostasis. It has been shown to improve balance in individuals with dizziness, and improve gait in Parkinson's disease (PD). This study was designed to determine if our pre-defined OMM protocol would improve motor function and balance in individuals with PD. METHODS: A randomized controlled trial to test OMM on balance and motor function in PD measured by the Mini-BESTest, Sensory Organization Test (SOT), and MDS-UPDRS...
October 31, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27814308/dance-therapy-improves-motor-and-cognitive-functions-in-patients-with-parkinson-s-disease
#17
Edoardo Rosario de Natale, Kai Stephan Paulus, Elena Aiello, Battistina Sanna, Andrea Manca, Giovanni Sotgiu, Paolo Tranquilli Leali, Franca Deriu
OBJECTIVE: To explore the effects of Dance Therapy (DT) and Traditional Rehabilitation (TR) on both motor and cognitive domains in Parkinson's Disease patients (PD) with postural instability. METHODS: Sixteen PD patients with recent history of falls were divided in two groups (Dance Therapy, DT and Traditional Rehabilitation, TR); nine patients received 1-hour DT classes twice per week, completing 20 lessons within 10 weeks; seven patients received a similar cycle of 20 group sessions of 60 minutes TR...
October 31, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27809706/oxidative-stress-and-mitochondrial-dysfunction-linked-neurodegenerative-disorders
#18
Md Torequl Islam
Reactive species play an important role in physiological functions. Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the failure of balance by the body's antioxidant enzyme systems results in destruction of cellular structures, lipids, proteins, and genetic materials such as DNA and RNA. Moreover, the effects of reactive species on mitochondria and their metabolic processes eventually cause a rise in ROS/RNS levels, leading to oxidation of mitochondrial proteins, lipids, and DNA...
November 3, 2016: Neurological Research
https://www.readbyqxmd.com/read/27802771/experiences-of-caring-for-a-family-member-with-parkinson-s-disease-a-meta-synthesis
#19
Rachael Theed, Fiona Eccles, Jane Simpson
OBJECTIVE: The aim of this qualitative meta-synthesis was to search and then synthesise family caregivers' experiences of providing care to individuals with Parkinson's disease (PD). METHOD: A systematic search resulted in the identification of 11 qualitative studies. Noblit and Hare's seven-stage approach was used to provide a higher-order interpretation of how family caregivers' experienced the effects of taking on a caregiving role. RESULTS: The process of reciprocal translation resulted in four overarching themes: (1) the need to carry on as usual - 'the caregiver must continue with his life'; (2) the importance of support in facilitating coping - 'I'm still going back to the support group'; (3) the difficult balancing act between caregiving and caregiver needs - 'I cannot get sick because I'm a caregiver'; (4) conflicts in seeking information and knowledge - 'maybe better not to know'...
November 2, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27798812/effects-of-an-intensive-nordic-walking-intervention-on-the-balance-function-and-walking-ability-of-individuals-with-parkinson-s-disease-a-randomized-controlled-pilot-trial
#20
Dae-Hyouk Bang, Won-Seob Shin
BACKGROUND: Parkinson's disease (PD) is associated with impairment in balance and postural control, accompanied by a progressive reduction in the speed and amplitude of movement. AIMS: The aim of our study was to evaluate the therapeutic effects of Nordic walking on a treadmill on the balance function and walking ability of individuals with PD. METHOD: Twenty participants with stage 1-3 PD in the Hoehn and Yahr scale were randomly allocated to the Nordic walking training (NWT) group and treadmill training (TT) group, with ten participants per group...
October 31, 2016: Aging Clinical and Experimental Research
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