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https://www.readbyqxmd.com/read/29055289/trends-in-incidence-and-associated-risk-factors-of-suicide-mortality-among-breast-cancer-patients
#1
Apostolos Gaitanidis, Michail Alevizakos, Michail Pitiakoudis, Doreen Wiggins
OBJECTIVE: Breast cancer patients are associated with an increased risk for committing suicide. The purpose of this study is to study the trends in the incidence of suicide mortality and identify pertinent risk factors among patients with breast cancer. METHODS: A retrospective examination of the Surveillance Epidemiology and End Results (SEER) database between years 1973 and 2013 was performed. RESULTS: Overall, 474,128 patients were identified of which 773 had committed suicide...
October 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29055269/decision-making-measured-by-the-iowa-gambling-task-in-alcohol-use-disorder-and-gambling-disorder-a-systematic-review-and-meta-analysis
#2
REVIEW
Ildikó Kovács, Mara J Richman, Zoltán Janka, Aniko Maraz, Bálint Andó
BACKGROUND AND AIMS: Gambling disorder (GD) and alcohol use disorder (AD) have similar features, such as elevated impulsivity and decision-making deficits, which are directly linked to relapse and poor therapeutic outcomes. Our aim was to assess decision-making characteristics in GD and AD patients compared to healthy controls (HC) based on one of the most frequently used measures of decision-making: the Iowa Gambling Task (IGT). METHODS: In our systematic literature search of three databases, we identified 1198 empirical articles that mentioned decision-making deficits with the use of the IGT in patients diagnosed with either AD or GD...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055268/early-age-of-e-cigarette-use-onset-mediates-the-association-between-impulsivity-and-e-cigarette-use-frequency-in-youth
#3
Krysten W Bold, Meghan E Morean, Grace Kong, Patricia Simon, Deepa R Camenga, Dana A Cavallo, Suchitra Krishnan-Sarin
BACKGROUND: Identifying risk factors for youth e-cigarette use is critical, given high rates of e-cigarette use and unknown health effects of long-term use. The current study examined whether an early age of onset of e-cigarette use mediates the association between impulsivity and e-cigarette frequency. METHODS: Cross-sectional survey data of e-cigarette users (n=927) were collected from 8 high schools in southeastern Connecticut. The sample was 44.7% female (mean age 16...
October 13, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055263/sub-cortical-brain-morphometry-and-its-relationship-with-cognition-in-rolandic-epilepsy
#4
Mahsa Shakeri, Alexandre N Datta, Domitille Malfait, Nadine Oser, Laurent Létourneau-Guillon, Philippe Major, Myriam Srour, Alan Tucholka, Samuel Kadoury, Sarah Lippé
PURPOSE: Rolandic epilepsy (RE), also called benign epilepsy with centrotemporal spikes (BECTS) is the most common childhood epilepsy syndrome. RE is associated with cognitive difficulties, which can affect children's quality of life. The underlying causes of these cognitive impairments are unclear. The objective of this prospective study is to investigate sub-cortical morphological alterations in RE children with left, right, or bilateral hemispheric focus and its association with cognition...
October 7, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29055261/the-nosas-score-a-new-and-simple-screening-tool-for-obstructive-sleep-apnea-syndrome-in-depressive-disorder
#5
Kelly Guichard, Helena Marti-Soler, Jean-Arthur Micoulaud-Franchi, Pierre Philip, Pedro Marques-Vidal, Peter Vollenweider, Gerard Waeber, Martin Preisig, José Haba-Rubio, Raphael Heinzer
BACKGROUND: Since the clinical presentation of obstructive sleep apnea syndrome (OSAS) shares common features with major depressive (MDE), the screening of OSAS is challenging in this population. The aim of this study was to assess the effectiveness of the NoSAS score in predicting the presence of OSAS among participants with current MDE and to compare it with the performance of existing screening tools. METHODS: A random sample of the population-based cohort CoLaus (Lausanne, Switzerland) underwent a psychiatric evaluation (PsyCoLaus) and a complete polysomnography at home (HypnoLaus)...
October 5, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29055244/a-pilot-study-comparing-mechanical-properties-of-tissue-engineered-cartilages-and-various-endogenous-cartilages
#6
Andrew K Pappa, Sajjad Soleimani, Montserrat Caballero, Alexandra E Halevi, John A van Aalst
BACKGROUND: Mechanical properties of tissue-engineered cartilage and a variety of endogenous cartilage were measured. The main goal was to evaluate if the tissue-engineered cartilage have similar mechanical characteristics to be replaced with rib cartilage in microtia reconstruction. Such study lays the foundation for future human clinical trials for microtia reconstruction. METHOD: Atomic force microscopy and compression testing were used to measure the viscoelasticity of tissue-engineered cartilage (stem cell seeded on Poly lactic co-glycolytic acid nanofibers and Pellet) and endogenous cartilage: conchal bowl, microtic ears, preauricular remnants, and rib...
October 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29055243/physiological-vital-sign-ranges-in-newborns-from-34-weeks-gestation-a-systematic-review
#7
REVIEW
Michelle Paliwoda, Karen New, Mark Davies, Fiona Bogossian
CONTEXT: The birth process and the moments thereafter are a crucial time for newborns as they adapt to extra uterine life. The adaptive process begins immediately and can take a number of days to complete. The process involves initiating and maintaining respirations, thermoregulation, and the change from foetal circulation to newborn circulation. The majority of newborns successfully adapt to extra uterine life, some experience difficulty. Early warning tools may assist clinicians identify early signs of failure to adapt and/or deterioration but these are dependent on 'Normal' vital sign reference ranges for triggering an escalation of care...
October 9, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29055218/cyp2c9-and-vkorc1-in-therapeutic-dosing-and-safety-of-acenocoumarol-treatment-implication-for-clinical-practice-in-hungary
#8
Reka Varnai, Csilla Sipeky, Lajos Nagy, Sandor Balogh, Bela Melegh
The purpose of this work was to investigate the contribution of CYP2C9 and VKORC1 to acenocoumarol (AC) dose variability, bleeding events in Hungary. The study recruited 117 patients on long-term AC therapy (INR 2-3), and 510 healthy individuals to model the findings. Patients were genotyped for alleles proved to affect lower AC overdose CYP2C9*2, CYP2C9*3, VKORC1*2. Additionally, we tested VKORC1*3, VKORC1*4 to examine their effect in patients with higher AC requirements. Most impact on dose reduction is accountable for CYP2C9*2/*3 (59%) and for VKORC1*2/*2 (45...
October 8, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29055217/trends-in-and-factors-affecting-the-observed-levels-of-urinary-inorganic-and-total-blood-mercury-among-us-children-adolescents-adults-and-senior-citizens-over-2005-2012
#9
Ram B Jain
Data from National Health and Nutrition Examination Survey (NHANES) for 2005-2012 were used to (i) study adjusted and unadjusted trends in the levels of urinary inorganic mercury (UIHG) and total blood mercury (TBHG) and (ii) factors that affect the observed levels of UIHG and TBHG among children aged 1-5 (CHLD15) and 6-11 (CHLD611) years, adolescents aged 12-19 years (ADOL), adults aged 20-64 years (ADLT), and senior citizens aged >=65 years (SNR). Decrease in adjusted levels of UIHG for each 2-year NHANES cycle for CHLD611 was 0...
September 6, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29055208/measuring-alcohol-use-across-the-transition-to-adulthood-racial-ethnic-sexual-identity-and-educational-differences
#10
Jessica N Fish, Amanda M Pollitt, John E Schulenberg, Stephen T Russell
BACKGROUND: Patterns of alcohol use change from adolescence to adulthood and may differ based on race/ethnicity, sexual identity, and education. If alcohol use measures do not operate consistently across groups and developmental periods, parameter estimates and conclusions may be biased. OBJECTIVES: To test the measurement invariance of a multi-item alcohol use measure across groups defined by race/ethnicity, sexual identity, and college education during the transition to adulthood...
October 12, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055207/hormonal-contraceptive-use-in-smokers-prevalence-of-use-and-associations-with-smoking-motives
#11
Alicia M Allen, Kim Lundeen, Lynn E Eberly, Sharon S Allen, Mustafa al'Absi, Myra Muramoto, Dorothy Hatsukami
INTRODUCTION: While endogenous sex hormones influence smoking-related outcomes, little is known about the role of hormonal contraceptives (HCs). This is despite dated estimates suggesting that HC use is prevalent among female smokers. Therefore, we sought to update estimates of the prevalence of HC use among female smokers and explore the association of HC use with various smoking motives (SMs). METHODS: This online cross-sectional survey recruited female smokers between the ages of 18-35...
October 13, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055174/maternal-outcomes-in-first-and-second-trimester-termination-of-pregnancy-which-are-the-risk-factors
#12
Giulia Garofalo, Anna Garofalo, Olga Sochirca, Maria Grazia Alemanno, Eleonora Pilloni, Marilisa Biolcati, Elisabetta Muccinelli, Elsa Viora, Tullia Todros
AIMS: To evaluate maternal complications of first trimester and second trimester termination of pregnancy (TOP) performed after first or second trimester positive prenatal diagnosis (PD). RESULTS: We performed a retrospective study from January 2007 to December 2011, on 844 patients, who underwent a TOP after positive amniocentesis or chorionic villus sampling (CVS) for foetal aneuploidies, performed for maternal age ≥35 years of age, positive prenatal screening (PS) or for genetic reasons...
October 21, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29055165/development-of-tripe-palms-and-soles-in-a-patient-with-long-pre-existing-systemic-mastocytosis-and-newly-developed-non-small-cell-lung-cancer
#13
Hanna Bonnekoh, Tatevik Ohanyan, Dido Lenze, Karoline Krause, Marcus Maurer, Torsten Zuberbier, Frank Siebenhaar
A 71-year old woman with systemic mastocytosis presented to our department with an apoplectic insult one year ago and a 100 pack year smoking history. Skin manifestation of mastocytosis had started at the age of 50 years accompanied by a substantial increase of serum tryptase since the age of 60. Bone marrow involvement was confirmed 16 years later. Therapy of mastocytosis included antihistamines, montelukast, sodium cromoglycate, and PUVA therapy, all with limited success. This article is protected by copyright...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29055156/type-2-diabetes-remission-2-years-post-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-the-role-of-the-weight-loss-and-comparison-of-diarem-and-diabetter-scores
#14
A Pucci, U Tymoszuk, W H Cheung, J M Makaronidis, S Scholes, G Tharakan, M Elkalaawy, M Guimaraes, M Nora, M Hashemi, A Jenkinson, M Adamo, M Monteiro, N Finer, R L Batterham
AIMS: The comparative efficacy of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy on Type 2 diabetes remission and the role of weight loss are unclear. The DiaRem Type 2 diabetes remission prediction score uses HbA1c , age and Type 2 diabetes medications but not Type 2 diabetes duration. The aim of this study was to compare the predictive value of the DiaRem score with the DiaBetter score that includes Type 2 diabetes duration, upon combined (complete plus partial) 2-year post-surgery Type 2 diabetes remission in people following RYGB and sleeve gastrectomy, and to investigate the relationship between weight loss and Type 2 diabetes remission...
October 21, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29055154/gene-expression-changes-in-male-accessory-glands-during-ageing-are-accompanied-by-reproductive-decline-in-drosophila-melanogaster
#15
Mareike Koppik, Claudia Fricke
Senescence is accompanied by loss of reproductive functions. Here we studied reproductive ageing in Drosophila melanogaster males and asked whether the expected decline in male reproductive success is due to diminished functionality of the male accessory gland. The male accessory gland produces the majority of seminal fluid proteins (SFPs) transferred to the female at mating. SFPs induce female post-mating changes and are key to male reproductive success. We measured age-dependent gene expression changes for five representative SFP genes in males from four different age groups ranging from one to six weeks after eclosion...
October 21, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29055147/cognitive-function-among-long-term-survivors-of-heart-transplantation
#16
Britta S Bürker, Einar Gude, Lars Gullestad, Ingelin Grov, Anne Relbo Authen, Arne K Andreassen, Odd E Havik, Mary Amanda Dew, Arnt E Fiane, Ira R Haraldsen, Ulrik F Malt, Stein Andersson
BACKGROUND: Cognitive impairment is documented early after heart transplantation (HTx), but we lack data on cognitive function beyond the fourth year posttransplant. Against the background of good long-term survival, this knowledge is necessary to improve clinical care throughout the entire posttransplant period. METHODS: We assessed cognitive function with a neuropsychological test battery in a sample of HTx recipients ≥16 years posttransplant. To improve clinical utility, we also applied adapted consensus criteria for Mild Cognitive Impairment (MCI)...
October 21, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29055146/association-between-natural-killer-cell-activity-and-the-risk-of-colorectal-neoplasia
#17
Yoon Suk Jung, Min-Jung Kwon, Dong Il Park, Chong Il Sohn, Jung Ho Park
BACKGROUND: Low activity of natural killer (NK) cells is known to be associated with higher risk of cancer, especially with poor prognosis and the presence of colorectal cancer (CRC). We investigated whether NK cells activity differs between subjects with and without colorectal neoplasia (CRN). METHODS: A cross-sectional study was performed on 1818 asymptomatic examinees aged ≥30 years who underwent NK cell activity test (which quantitates the amount of interferon-γ secreted into the plasma by NK cells) and a colonoscopy as part of a health check-up...
October 21, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29055133/estimating-diversification-rates-for-higher-taxa-bamm-can-give-problematic-estimate-of-rates-and-rate-shifts
#18
Andreas L S Meyer, John J Wiens
Estimates of diversification rates are invaluable for many macroevolutionary studies. Recently, an approach called BAMM (Bayesian Analysis of Macro-evolutionary Mixtures) has become widely used for estimating diversification rates and rate shifts. At the same time, several papers have concluded that estimates of net diversification rates from the method-of-moments (MS) estimators are inaccurate. Yet, no studies have compared the ability of these two methods to accurately estimate clade diversification rates...
October 21, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29055131/case-report-of-staphylococcus-epidermidis-maternal-sepsis-and-chorioamnionitis-following-fetoscopy
#19
Gabriel Levin, Roy Zigron
A patient aged 28 years (gravida 5 para 3) who was at 21 weeks of a monochorionic diamniotic pregnancy, underwent fetoscopic laser ablation of placental blood vessels owing to stage-3 twin-to-twin transfusion syndrome (Figure 1). Ultrasonography on post-operative day 1 demonstrated marked improvement of both embryo urinary bladder filling and Doppler blood flow measurements. This article is protected by copyright. All rights reserved.
October 21, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29055119/deep-brain-stimulation-of-the-nucleus-basalis-of-meynert-attenuates-early-eeg-components-associated-with-defective-sensory-gating-in-patients-with-alzheimer-disease-a-two-case-study
#20
Stefan Dürschmid, Christoph Reichert, Jens Kuhn, Hans-Joachim Freund, Hermann Hinrichs, Hans-Jochen Heinze
Alzheimer's disease (AD) is associated with deterioration of memory and cognitive function and a degeneration of neurons of the nucleus basalis of Meynert (NBM). The NBM is the major input source of Acetylcholine (ACh) to the cortex. The decreasing cholinergic innervation of the cortex due to degeneration of the NBM might be the cause of loss of memory function. NBM-Deep Brain Stimulation (NBM-DBS) is considered to serve as a potential therapeutic option for AD patients by supporting residual cholinergic transmission to stabilize oscillatory activity in memory relevant circuits...
October 20, 2017: European Journal of Neuroscience
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