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https://www.readbyqxmd.com/read/29909603/urinary-outcomes-in-patients-with-down-s-syndrome-and-hirschsprung-s-disease
#1
Alexander Johannes Martinus Dingemans, Carlos Albert Reck-Burneo, Molly Fuchs, Alejandra Vilanova Sanchez, Victoria Alison Lane, Erin Hoover, Tassiana Maloof, Laura Weaver, Marc A Levitt, Richard J Wood
INTRODUCTION:  Previous research in children with Hirschsprung's disease (HD) and Down's syndrome (DS) has focused on colorectal outcomes. We set out to review urinary outcomes in this patient group. METHODS:  The medical records of all patients aged five years and older with HD were reviewed, and patients and caregivers filled out the Vancouver Symptom Score at intake, which is designed and validated to diagnose dysfunctional elimination syndrome. RESULTS:  A total of 104 patients with HD were included in this study...
June 17, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29909602/traumatic-stress-among-school-aged-pediatric-surgery-patients-and-their-parents
#2
Amichai Ben Ari, Daniella Margalit, Raphael Udassin, Fortu Benarroch
INTRODUCTION:  Since hospitalization can be a traumatic event for children, many of them may suffer from a cluster of chronic psychological and emotional difficulties called Pediatric Medical Traumatic Stress (PMTS). Although PMTS causes considerable functional impairment and psychological distress and may decrease the children's compliance with post-surgical care, awareness of this condition is low and thus not enough effort is made to prevent it. The objective of this study is to assess prospectively the prevalence and characteristics of PMTS in school-age children following hospitalization in a general pediatric surgery ward and in their parents, which has not been documented before...
June 17, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29909600/patients-knowledge-about-the-outcomes-of-thyroid-biopsy-a-patient-survey
#3
Naykky Singh Ospina, Ana Castaneda-Guarderas, Russell Ward, Juan P Brito, Spyridoula Maraka, Claudia Zeballos Palacios, Kathleen J Yost, Diana S Dean, Victor M Montori
PURPOSE: Fine-needle aspiration biopsy of the thyroid is an increasingly common outpatient procedure. Patients are counseled about the indications and risks of this procedure and informed consent is obtained. We aimed to assess the extent to which patients acquired necessary knowledge during this process. METHODS: Survey study conducted in a thyroid nodule clinic at a referral center. Adult patients who had just undergone a thyroid biopsy were asked to complete a survey, including eight questions regarding the indications and potential outcomes of thyroid biopsy...
June 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29909599/survival-of-aggressive-variants-of-papillary-thyroid-carcinoma-in-patients-under-55-years-old-a-seer-population-based-retrospective-analysis
#4
Jianhua Feng, Fei Shen, Wensong Cai, Xiaoxiong Gan, Xingyan Deng, Bo Xu
BACKGROUND: Patients younger than 55 years of age with papillary thyroid carcinoma (PTC) have excellent survival. Diffuse sclerosing variant (DSV) and tall cell variant (TCV) of PTC are associated with aggressiveness; the survival of patients <55 years of age with these variants is still unclear. We aim to investigate the clinicopathological features and survival of these variants in the age group <55 years. METHODS: All adult patients (<55 years old) with DSV, TCV and conventional PTC (CPTC) came from the Surveillance, Epidemiology, and End Results program (1988-2013)...
June 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29909593/imaging-of-kingella-kingae-musculoskeletal-infections-in-children-a-series-of-5-cases
#5
Jie C Nguyen, Susan L Rebsamen, Michael J Tuite, J Muse Davis, Humberto G Rosas
PURPOSE: Kingella kingae musculoskeletal infections continue to be under-diagnosed and there remains a paucity of literature on its imaging features. The purpose of this manuscript is to review the imaging, clinical, and laboratory findings of microbiology-proven K. kingae infections. MATERIALS AND METHODS: A retrospective review of musculoskeletal infections between January 1, 2013 and Dec 31, 2016 yielded 134 patients from whom 5 patients had confirmed K. kingae infections (3 boys and 2 girls, mean age of 16 months, range 9-38 months)...
June 16, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29909583/clinical-and-radiographical-ten-years-long-term-outcome-of-microfracture-vs-autologous-chondrocyte-implantation-a-matched-pair-analysis
#6
Robert Ossendorff, Kilian Franke, Benjamin Erdle, Markus Uhl, Norbert P Südkamp, Gian M Salzmann
PURPOSE: To compare the clinical and radiographical long-term outcome of microfracture (MFX) and first-generation periosteum-covered autologous chondrocyte implantation (ACI-P). METHODS: All subjects (n = 86) who had been treated with knee joint ACI-P or microfracture (n = 76) with a post-operative follow-up of at least ten years were selected. Clinical pre- and post-operative outcomes were analyzed by numeric analog scale (NAS) for pain, Lysholm, Tegner, IKDC, and KOOS score...
June 16, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29909577/population-pharmacokinetic-model-for-tumescent-lidocaine-in-women-undergoing-breast-cancer-surgery
#7
Camille Riff, Aurélie Bourgoin, Amelie Marsot, Laurent Allanioux, Marc Leone, Olivier Blin, Romain Guilhaumou
PURPOSE: Tumescent lidocaine anesthesia (TLA) is an opportunity to perform mastectomy for breast cancer without general anesthesia in elderly women. Few reports are available on the pharmacokinetics of lidocaine in a context of TLA during a unilateral mastectomy. The aim of this study was to describe lidocaine pharmacokinetics in elderly women undergoing breast cancer surgery after TLA and to explore the risk of the toxicity of this technique. METHODS: A prospective study was conducted to examine the pharmacokinetics of lidocaine in women undergoing TLA...
June 16, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29909564/organized-screening-detects-breast-cancer-at-earlier-stage-regardless-of-molecular-phenotype
#8
Claire M B Holloway, Li Jiang, Marlo Whitehead, Jennifer M Racz, Patti A Groome
PURPOSE: Mortality reduction attributable to organized breast screening is modest. Screening may be less effective at detecting more aggressive cancers at an earlier stage. This study was conducted to determine the relative efficacy of screening mammography to detect cancers at an earlier stage by molecular phenotype. METHODS: We identified 2882 women with primary invasive breast cancer diagnosed between January 1, 2008 and December 31, 2012 and who had a mammogram through the Ontario Breast Screening Program in the 28 months before diagnosis...
June 16, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29909560/rhinencephalon-changes-in-tuberous-sclerosis-complex
#9
Renzo Manara, Davide Brotto, Samuela Bugin, Maria Federica Pelizza, Stefano Sartori, Margherita Nosadini, Sara Azzolini, Giorgio Iaconetta, Cecilia Parazzini, Alessandra Murgia, Angela Peron, Paola Canevini, Francesca Labriola, Aglaia Vignoli, Irene Toldo
PURPOSE: Despite complex olfactory bulb embryogenesis, its development abnormalities in tuberous sclerosis complex (TSC) have been poorly investigated. METHODS: Brain MRIs of 110 TSC patients (mean age 11.5 years; age range 0.5-38 years; 52 female; 26 TSC1, 68 TSC2, 8 without mutation identified in TSC1 or TSC2, 8 not tested) were retrospectively evaluated. Signal and morphological abnormalities consistent with olfactory bulb hypo/aplasia or with olfactory bulb hamartomas were recorded...
June 17, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29909557/defining-normal-apical-vaginal-support-a-relook-at-the-posst-study
#10
Radhika Patnam, Autumn Edenfield, Steven Swift
INTRODUCTION AND HYPOTHESIS: The purpose of this study is to reanalyze data from the original 2005 Pelvic Organ Support Study (POSST) data set to define normal values for apical Pelvic Organ Prolapse Quantification (POP-Q) points C and D and total vaginal length (TVL) in an asymptomatic population of women. METHODS: In this retrospective observational data-set review, patient were >18 years presenting for annual gynecologic exams to six centers in the United States...
June 16, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29909556/the-urinary-microbiome-in-women-with-mixed-urinary-incontinence-compared-to-similarly-aged-controls
#11
Yuko M Komesu, Holly E Richter, Benjamin Carper, Darrell L Dinwiddie, Emily S Lukacz, Nazema Y Siddiqui, Vivian W Sung, Halina M Zyczynski, Beri Ridgeway, Rebecca G Rogers, Lily A Arya, Donna Mazloomdoost, Marie G Gantz
INTRODUCTION & HYPOTHESIS: Previous studies have suggested that women with urinary incontinence have an altered urinary microbiome. We hypothesized that the microbiome in women with mixed urinary incontinence (MUI) differed from controls and tested this hypothesis using bacterial gene sequencing techniques. METHODS: This multicenter study compared the urinary microbiome in women with MUI and similarly aged controls. Catheterized urine samples were obtained; v4-6 regions of the 16S rRNA gene were sequenced to identify bacteria...
June 16, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29909552/early-outcomes-of-270-degree-spinal-canal-decompression-by-using-tessys-isee-technique-in-patients-with-lumbar-spinal-stenosis-combined-with-disk-herniation
#12
Chengjie Xiong, Tao Li, Hui Kang, Hao Hu, Jing Han, Feng Xu
PURPOSE: Traditional open approach is an efficient way to treat lumbar spinal stenosis (SS) combined with disk herniation (DH); however, risk factors such as advanced age, osteoporosis etc. are associated with the complications after the surgery. This study aims to analyze the early clinical and radiological outcomes of treatment on SS&DH by using newly developed minimal invasive TESSYS-ISEE technique. METHODS: Patients with limp and unilateral lower limb radiculopathy underwent minimal invasive surgery by using TESSYS-ISEE technique...
June 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29909548/molecular-heterogeneity-and-cxorf67-alterations-in-posterior-fossa-group-a-pfa-ependymomas
#13
Kristian W Pajtler, Ji Wen, Martin Sill, Tong Lin, Wilda Orisme, Bo Tang, Jens-Martin Hübner, Vijay Ramaswamy, Sujuan Jia, James D Dalton, Kelly Haupfear, Hazel A Rogers, Chandanamali Punchihewa, Ryan Lee, John Easton, Gang Wu, Timothy A Ritzmann, Rebecca Chapman, Lukas Chavez, Fredrick A Boop, Paul Klimo, Noah D Sabin, Robert Ogg, Stephen C Mack, Brian D Freibaum, Hong Joo Kim, Hendrik Witt, David T W Jones, Baohan Vo, Amar Gajjar, Stan Pounds, Arzu Onar-Thomas, Martine F Roussel, Jinghui Zhang, J Paul Taylor, Thomas E Merchant, Richard Grundy, Ruth G Tatevossian, Michael D Taylor, Stefan M Pfister, Andrey Korshunov, Marcel Kool, David W Ellison
Of nine ependymoma molecular groups detected by DNA methylation profiling, the posterior fossa type A (PFA) is most prevalent. We used DNA methylation profiling to look for further molecular heterogeneity among 675 PFA ependymomas. Two major subgroups, PFA-1 and PFA-2, and nine minor subtypes were discovered. Transcriptome profiling suggested a distinct histogenesis for PFA-1 and PFA-2, but their clinical parameters were similar. In contrast, PFA subtypes differed with respect to age at diagnosis, gender ratio, outcome, and frequencies of genetic alterations...
June 16, 2018: Acta Neuropathologica
https://www.readbyqxmd.com/read/29909545/coalitional-physical-competition-acute-salivary-steroid-hormone-responses-among-juvenile-male-soccer-players-in-hong-kong
#14
Timothy S McHale, Wai-Chi Chee, Ka-Chun Chan, David T Zava, Peter B Gray
A large body of research links testosterone and cortisol to male-male competition. Yet, little work has explored acute steroid hormone responses to coalitional, physical competition during middle childhood. Here, we investigate testosterone, dehydroepiandrosterone (DHEA), androstenedione, and cortisol release among ethnically Chinese boys in Hong Kong (N = 102), aged 8-11 years, during a soccer match (n = 84) and an intrasquad soccer scrimmage (n = 81), with 63 participants competing in both treatments. The soccer match and intrasquad soccer scrimmage represented out-group and in-group treatments, respectively...
June 16, 2018: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/29909515/influence-of-biliopancreatic-diversion-on-pregnancy-outcomes-in-comparison-to-other-bariatric-surgery-procedures
#15
S De Carolis, A Botta, Gelsomina Del Sordo, R Guerrisi, S Salvi, M P De Carolis, A Iaconelli, P Giustacchini, M Raffaelli, A Lanzone
BACKGROUND: Pregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures. METHODS: We conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst which n = 51 after biliopancreatic diversion (BPD) and n = 58 after non-malabsorptive procedures...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909508/associations-of-mental-health-and-sleep-duration-with-menstrual-cycle-irregularity-a-population-based-study
#16
Taeryoon Kim, Ga Eun Nam, Byoungduck Han, Sung Jung Cho, Junghun Kim, Do Hyun Eum, Sang Woo Lee, Soon Hong Min, Woohyun Lee, Kyungdo Han, Yong Gyu Park
This study aimed to examine whether the characteristics of mental health and sleep duration, alone or in combination, are associated with menstrual cycle irregularity. This population-based, cross-sectional study analyzed the data from 4445 women aged 19-49 years, who participated in the Korea National Health and Nutrition Examination Survey 2010-2012. A structured questionnaire was used to assess mental health characteristics, sleep duration, and menstrual cycle irregularity. A multivariable logistic regression analysis was performed...
June 16, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29909505/ultrasonographic-reference-values-for-the-deep-branch-of-the-radial-nerve-at-the-arcade-of-frohse
#17
Arash Babaei-Ghazani, Peyman Roomizadeh, Golshan Sanaei, Saeideh Najarzadeh-Mehdikhani, Kimia Habibi, Shahin Nikmanzar, Yadollah Kheyrollah
PURPOSE: The deep branch of the radial nerve (DBRN) enters the forearm as it passes under the arcade of Frohse. This is the most common entrapment site of the DBRN in the forearm. In this study, we investigated the ultrasonographic reference values for the diameters and cross-sectional area (CSA) of the DBRN at the level of the arcade of Frohse in a healthy sample of the population. METHODS: Sixty-five healthy Caucasian volunteers (130 nerves) were recruited for this study...
June 16, 2018: Journal of Ultrasound
https://www.readbyqxmd.com/read/29909503/prophylactic-antibiotics-in-pediatric-neurological-surgery
#18
Friederike Knerlich-Lukoschus, Martina Messing-Jünger
PURPOSE: Surgical antibiotic prophylaxis (SAP) in pediatric neurosurgery has poorly been characterized until now. This review gives an overview on the current literature extracting recommendations and guidelines. METHODS: The current literature on SAP with special forcus on pediatric neurosurgerical procedures was reviewed. Further, available recommendations in online databases were checked. Clean neurosurgical, shunt, and implant surgeries are considered separately...
June 16, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29909501/decreasing-rates-of-major-lower-extremity-amputation-in-people-with-diabetes-but-not-in-those-without-a-nationwide-study-in-belgium
#19
Heiner Claessen, Herve Avalosse, Joeri Guillaume, Maria Narres, Tatjana Kvitkina, Werner Arend, Stephan Morbach, Patrick Lauwers, Frank Nobels, Jacques Boly, Chris Van Hul, Kris Doggen, Isabelle Dumont, Patricia Felix, Kristien Van Acker, Andrea Icks
AIMS/HYPOTHESIS: The reduction of major lower-extremity amputations (LEAs) is one of the main goals in diabetes care. Our aim was to estimate annual LEA rates in individuals with and without diabetes in Belgium, and corresponding time trends. METHODS: Data for 2009-2013 were provided by the Belgian national health insurance funds, covering more than 99% of the Belgian population (about 11 million people). We estimated the age-sex standardised annual amputation rate (first per year) in the populations with and without diabetes for major and minor LEAs, and the corresponding relative risks...
June 16, 2018: Diabetologia
https://www.readbyqxmd.com/read/29909498/leisure-participation-patterns-for-school-age-youth-with-autism-spectrum-disorders-findings-from-the-2016-national-survey-of-children-s-health
#20
Karen Ratcliff, Ickpyo Hong, Claudia Hilton
Leisure activity participation is important for health and well-being. This study examined similarities and differences between typically developing children and those with autism spectrum disorders (ASD) from 6 to 17 years old in physical, recreational, social, skill, and jobs/chores activities from a large national database. Findings revealed that children with ASD had significantly lower participation levels than those without ASD between 11 and 17 years old. They suggest an increasing disparity among many types of leisure participation for children and youth with ASD as they age, eventually leading to limited participation in adult activities...
June 16, 2018: Journal of Autism and Developmental Disorders
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