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https://www.readbyqxmd.com/read/28538914/the-regulation-and-adoption-of-health-technologies-under-brazil-s-unified-health-system-barriers-to-access-to-medicines-for-diseases-of-poverty
#1
Rafael Santos Santana, Evandro de Oliveira Lupatini, Silvana Nair Leite
The study aimed to examine the regulation and adoption of health technologies for the diseases of poverty in the Brazil's Unified Health System (SUS). An exploratory, descriptive study was conducted between January and May 2016 consisting of the search and analysis of relevant documents on the websites of Brazil's National Health Surveillance Agency, the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), the National Commission for the Adoption of Technologies by the SUS, and Saúde Legis (the Ministry of Health's Legislation System)...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28535106/value-tools-in-managed-care-decision-making-current-hurdles-and-future-opportunities
#2
Jeremy Schafer, Dominic Galante, Jason Shafrin
BACKGROUND: Organizations such as the National Comprehensive Cancer Network, American Society of Clinical Oncology, Institute for Clinical and Economic Review, and Memorial Sloan Kettering have created distinct tools to help different stakeholders assess the value of oncology treatments. However, the oncology value tools were not necessarily created for payers, and it is unclear whether payers are using these tools as part of their drug management process. OBJECTIVE: To understand what value tools payers are using in oncology management and what benefits and shortcomings the tools may have from the payer perspective...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28529669/veggie-van-pilot-study-impact-of-a-mobile-produce-market-for-underserved-communities-on-fruit-and-vegetable-access-and-intake
#3
Lucia A Leone, Lindsey Haynes-Maslow, Alice S Ammerman
We conducted a pilot evaluation of the Veggie Van, a mobile produce market that brings weekly boxes of reduced-cost locally grown fruits and vegetables (F&V) to lower-income communities and offers cooking and nutrition education to customers. We conducted surveys just prior to starting Veggie Van at each of 3 sites and again at 2-3 months. F&V intake was measured with a 2-question item and a 10-item food frequency questionnaire (FFQ) in a subset of participants. At baseline, average servings/day of F&V was 4...
2017: Journal of Hunger & Environmental Nutrition
https://www.readbyqxmd.com/read/28526075/testing-times-trends-in-availability-price-and-market-share-of-malaria-diagnostics-in-the-public-and-private-healthcare-sector-across-eight-sub-saharan-african-countries-from-2009-to-2015
#4
Kara Hanson, Catherine Goodman
BACKGROUND: The World Health Organization guidelines have recommended that all cases of suspected malaria should receive a confirmatory test with microscopy or a malaria rapid diagnostic test (RDT), however evidence from sub-Saharan Africa (SSA) illustrates that only one-third of children under five with a recent fever received a test. The aim of this study was to evaluate availability, price and market share of microscopy and RDT from 2009/11 to 2014/15 in 8 SSA countries, to better understand barriers to improving access to malaria confirmatory testing in the public and private health sectors...
May 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28522099/psychometric-properties-and-dutch-norm-values-of-the-children-s-sleep-habits-questionnaire-in-toddlers
#5
Lindsay Martina Helena Steur, Eva Henriëtte Visser, Martha Alexandra Grootenhuis, Caroline Barbara Terwee, Gerardus Johannes Laurentius Kaspers, Raphaële Reine Lydie van Litsenburg
OBJECTIVE: The Children's Sleep Habits Questionnaire (CSHQ) was developed in the USA for children aged 4-10 years. The Dutch CSHQ has been validated for this age group, but not yet for toddlers. Furthermore, Dutch norm values for toddlers are unavailable. This study aimed to investigate the psychometric properties and collect norm values of the Dutch CSHQ in toddlers. METHODS: Data collection was conducted by Taylor Nelson Sofres Netherlands Institute for Public Opinion (TNS-NIPO), a Dutch market research agency...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28522031/-the-french-medecine-pricing-committee-and-the-medicine-economic-policy-rules-and-competences
#6
D Giorgi
The French medicine pricing committee (CEPS), a governmental and inter-institutional body exercises essential competences for the regulation of the economy of the reimbursable drugs in France. It provides a good example of administered price regulation. It also supervises the proper use of products (control of promotion, conventional control of sales volumes). Finally, it regulates the annual envelope of drug expenditures by means of discounts paid by pharmaceutical companies. The article presents the legal criteria and the doctrine of price setting used in France...
May 15, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28518088/in-vitro-methods-for-comparing-target-binding-and-cdc-induction-between-therapeutic-antibodies-applications-in-biosimilarity-analysis
#7
Nohemi Salinas-Jazmín, Edith González-González, Luz X Vásquez-Bochm, Sonia M Pérez-Tapia, Marco A Velasco-Velázquez
Therapeutic monoclonal antibodies (mAbs) are relevant to the treatment of different pathologies, including cancers. The development of biosimilar mAbs by pharmaceutical companies is a market opportunity, but it is also a strategy to increase drug accessibility and reduce therapy-associated costs. The protocols detailed here describe the evaluation of target binding and CDC induction by rituximab in Daudi cells. These two functions require different structural regions of the antibody and are relevant to the clinical effect induced by rituximab...
May 4, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28514702/nanoscale-morphological-analysis-of-soft-matter-aggregates-with-fractal-dimension-ranging-from-1-to-3
#8
REVIEW
Francesco Valle, Marco Brucale, Stefano Chiodini, Eva Bystrenova, Cristiano Albonetti
While the widespread emergence of nanoscience and nanotechnology can be dated back to the early eighties, the last decade has witnessed a true coming of age of this research field, with novel nanomaterials constantly finding their way into marketed products. The performance of nanomaterials being dominated by their nanoscale morphology, their quantitative characterization with respect to a number of properties is often crucial. In this context, those imaging techniques able to resolve nanometer scale details are clearly key players...
May 4, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28513261/rainer-gross-award-lecture-2016
#9
Saurabh Mehta, Susannah Colt, Seoho Lee, David Erickson
The need for improving methods of nutritional assessment and delivering primary health care globally cannot be overemphasized. While advances in medical technology typically create more disparities because of access being limited to resource-rich settings, a transition of health care to a mobile platform is increasingly leveling the field. Technological advances offer opportunities to scale laboratory procedures down to mobile devices, such as smartphones and tablets. Globalization also provides the required infrastructure and network capacity to support the use of mobile health devices in developing settings where nutritional deficiencies are most prevalent...
June 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28509712/accelerating-access-and-scale-up-of-optimized-art-in-low-income-and-middle-income-countries-a-call-for-a-coordinated-end-to-end-approach
#10
Emily Harris, Carmen Pérez-Casas, Matthew Barnhart, Amy H Lin, Danielle Ferris, Olawale Ajose, Emma K Burgess, Rachel Fowler
PURPOSE OF REVIEW: To discuss how aligning the collective power of scientists, regulators, drug companies, donors, implementers and advocates to achieve a single goal - accelerating access to simpler, safer, more robust and more affordable HIV treatment - can rapidly advance antiretroviral optimization efforts and enable scale-up. RECENT FINDINGS: Harmonization of traditionally sequential processes can address the delays commonly experienced in introducing new products to low-income and middle-income countries, by facilitating an 'end-to-end' approach that mitigates risk and encourages early planning for all aspects of product introduction...
May 15, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28507222/meeting-the-goal-of-concurrent-adolescent-and-adult-licensure-of-hiv-prevention-and-treatment-strategies
#11
Michelle Hume, Linda L Lewis, Robert M Nelson
The ability of adolescents to access safe and effective new products for HIV prevention and treatment is optimised by adolescent licensure at the same time these products are approved and marketed for adults. Many adolescent product development programmes for HIV prevention or treatment products may proceed simultaneously with adult phase III development programmes. Appropriately implemented, this strategy is not expected to delay licensure as information regarding product efficacy can often be extrapolated from adults to adolescents, and pharmacokinetic properties of drugs in adolescents are expected to be similar to those in adults...
May 15, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28504058/south-korean-anthropometric-data-and-survey-methodology-size-korea
#12
Jung Yong Kim, Jae Woo You, Mi Sook Kim
Considering the many emerging markets in East Asia, access to contemporary anthropometric data for this region is important for designers and manufacturers seeking to produce the best fitting products and living environments for consumers. The purpose of this paper is to describe Korean anthropometric data collection and survey techniques for those who are interested in ethnic characteristics, conducting surveys, and formulating ergonomic product designs for South Korean and, more broadly, East Asian populations...
May 15, 2017: Ergonomics
https://www.readbyqxmd.com/read/28503773/the-table-grape-victoria-with-a-long-shaped-berry-a-potential-mutation-with-attractive-characteristics-for-consumers
#13
Giuseppe Ferrara, Alessandra Gallotta, Carmela Pacucci, Angela Maria Stella Matarrese, Andrea Mazzeo, Angelica Giancaspro, Agata Gadaleta, Francesca Piazzolla, Giancarlo Colelli
BACKGROUND: Puglia is the most important region in Italy for table grape production. Since consumers look for new products, the number of table grape varieties is strongly increasing in the last years. RESULTS: In a survey in the Puglia region, we identified several years ago a potential mutation of the cv. Victoria. We described this accession in comparison with the standard Victoria for some amphelographic characteristics. All the characteristics were very similar to the standard Victoria except for the berry shape, which was significantly more elongated...
May 15, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28499932/dietary-customs-and-food-availability-shape-the-preferences-for-basic-tastes-a-cross-cultural-study-among-polish-tsimane-and-hadza-societies
#14
Agnieszka Sorokowska, Robert Pellegrino, Marina Butovskaya, Michalina Marczak, Agnieszka Niemczyk, Tomas Huanca, Piotr Sorokowski
Biological significance of food components suggests that preferences for basic tastes should be similar across cultures. On the other hand, cultural factors play an important role in diet and can consequently influence individual preference for food. To date, very few studies have compared basic tastes preferences among populations of very diverse environmental and cultural conditions, and research rather did not involve traditional populations for whom the biological significance of different food components might be the most pronounced...
May 9, 2017: Appetite
https://www.readbyqxmd.com/read/28499318/-psychiatric-inpatient-treatment-and-return-to-work
#15
Lena Mernyi, Patricia Hölzle, Johannes Hamann
Objective People with mental diseases have a high risk of unemployment and they have only limited access to the labor market. The return to work is often associated with fears.The present study aims to provide an overview of the number of hospitalized psychiatric patients with permanent employment. Moreover it should give an insight into the process of return to work, the experiences patients gain and the support they receive. Methods In the participating clinics we measured the number of patients with permanent employment...
May 12, 2017: Psychiatrische Praxis
https://www.readbyqxmd.com/read/28498831/dynamics-of-analyst-forecasts-and-emergence-of-complexity-role-of-information-disparity
#16
Chansoo Kim, Daniel S Kim, Kwangwon Ahn, M Y Choi
We report complex phenomena arising among financial analysts, who gather information and generate investment advice, and elucidate them with the help of a theoretical model. Understanding how analysts form their forecasts is important in better understanding the financial market. Carrying out big-data analysis of the analyst forecast data from I/B/E/S for nearly thirty years, we find skew distributions as evidence for emergence of complexity, and show how information asymmetry or disparity affects financial analysts' forming their forecasts...
2017: PloS One
https://www.readbyqxmd.com/read/28498575/implementing-shared-decision-making-in-routine-mental-health-care
#17
Mike Slade
Shared decision making (SDM) in mental health care involves clinicians and patients working together to make decisions. The key elements of SDM have been identified, decision support tools have been developed, and SDM has been recommended in mental health at policy level. Yet implementation remains limited. Two justifications are typically advanced in support of SDM. The clinical justification is that SDM leads to improved outcome, yet the available empirical evidence base is inconclusive. The ethical justification is that SDM is a right, but clinicians need to balance the biomedical ethical principles of autonomy and justice with beneficence and non-maleficence...
June 2017: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/28498314/photoactive-hybrid-catalysts-based-on-natural-and-synthetic-polymers-a-comparative-overview
#18
REVIEW
Juan Carlos Colmenares, Ewelina Kuna
In the present review, we would like to draw the reader's attention to the polymer-based hybrid materials used in photocatalytic processes for efficient degradation of organic pollutants in water. These inorganic-organic materials exhibit unique physicochemical properties due to the synergistic effect originating from the combination of individual elements, i.e., photosensitive metal oxides and polymeric supports. The possibility of merging the structural elements of hybrid materials allows for improving photocatalytic performance through (1) an increase in the light-harvesting ability; (2) a reduction in charge carrier recombination; and (3) prolongation of the photoelectron lifetime...
May 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28494421/forest-protected-areas-governance-in-zimbabwe-shift-needed-away-from-a-long-history-of-local-community-exclusion
#19
V T Mutekwa, J Gambiza
In this literature review based paper we explored the concept of exclusion of local communities from accessing resources in forest protected areas (FPAs) in Zimbabwe. We discussed the colonial and post-colonial forms, causes and mechanisms of exclusion and their social, economic and ecological outcomes. We examined the range of powers embodied in and exercised through various mechanisms, processes and social relations and their impact on local communities' access to FPA resources and associated benefits along the historical trajectory of forest governance in Zimbabwe...
May 7, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28491071/exploring-blueberry-aroma-complexity-by-chromatographic-and-direct-injection-spectrometric-techniques
#20
Brian Farneti, Iuliia Khomenko, Marcella Grisenti, Matteo Ajelli, Emanuela Betta, Alberto Alarcon Algarra, Luca Cappellin, Eugenio Aprea, Flavia Gasperi, Franco Biasioli, Lara Giongo
Blueberry (Vaccinium spp.) fruit consumption has increased over the last 5 years, becoming the second most important soft fruit species after strawberry. Despite the possible economic and sensory impact, the blueberry volatile organic compound (VOC) composition has been poorly investigated. Thus, the great impact of the aroma on fruit marketability stimulates the need to step forward in the understanding of this quality trait. Beside the strong effect of ripening, blueberry aroma profile also varies due to the broad genetic differences among Vaccinium species that have been differently introgressed in modern commercial cultivars through breeding activity...
2017: Frontiers in Plant Science
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