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Mary Anne Nurmi, Corey S Mackenzie, Kerstin Roger, Kristin Reynolds, James Urquhart
Although participating in community social programming is associated with positive physical and mental health outcomes for older adults, older men participate less often than women. Men's Sheds is a community programme used primarily by older men that originated in Australia and is well established there. The goal of the current study was to explore men's perceptions of the need for Men's Sheds and issues concerning access to them in Canada, a country with a small but growing Men's Sheds movement. We conducted focus groups with 64 men aged 55 years and older, including Men's Sheds members and men from the community who were unfamiliar with this programme, and analysed the data using the framework analytic approach...
April 2018: Ageing and Society
Olinda Timms
The introduction of the Surrogacy (Regulation) Bill, 2016 into Parliament, in August 2016, was a much-awaited response to citizen voices and human rights groups calling for action in the unregulated area of commercial surrogacy arrangements. Both houses of Parliament have reviewed the Bill, and its fate was to be decided in the Winter Session of Parliament, 2017. It is still unclear whether the Bill will come up for decision in the Budget Session that will reconvene on March 5, 2018. The market for infertility treatments has attracted to India global clients seeking access to surrogates and procedures at lower costs...
March 5, 2018: Indian Journal of Medical Ethics
Yibeltal Assefa, Peter S Hill, Owain D Williams
At September's 2017 United Nations General Assembly, a state-of-the-art HIV medicine was announced to be made available at just $75 per person per year. There have been a number of strategies that the global AIDS community and countries have utilized to reduce prices and make antiretrovirals (ARVs) accessible for people living with HIV/AIDS. There appears to be an opportunity for the treatment of hepatitis C virus infection using direct-acting antivirals (DAAs) to benefit from the often painful and laboured history of driving down the prices of ARVs...
March 14, 2018: International Journal of Infectious Diseases: IJID
Elle Wadsworth, Colin Drummond, Paolo Deluca
The Internet has played a major role in the distribution of New Psychoactive Substances (NPS), and crypto markets are increasingly used for the anonymous sale of drugs, including NPS. This study explores the availability of individual NPS and vendors on the crypto markets and considers whether crypto markets are a reliable platform for the sale of NPS. Data was collected from 22 crypto markets that were accessed through the hidden web using the Onion Router (Tor). Data collection took place bimonthly from October 2015 to October 2016 as part of the CASSANDRA ( C omputer A ssisted S olutions for S tudying the A vailability a N d D ist R ibution of novel psycho A ctive substances) project...
March 16, 2018: Brain Sciences
Jan Endrikat, Susan Dohanish, Nicolas Schleyer, Susanne Schwenke, Sheela Agarwal, Thomas Balzer
OBJECTIVES: The aim of this study was to critically assess the evaluation and categorization process for nephrogenic systemic fibrosis (NSF) based on reports received by Bayer from 2006 to 2016. MATERIALS AND METHODS: A total of 779 NSF reports received by Bayer globally from 2006 to 2016 were included in the analysis. Arlington Medical Resources provided gadolinium-based contrast agent (GBCA) market share. Reports were conservatively categorized based on the Cowper/Girardi criteria...
March 16, 2018: Investigative Radiology
H Rachidi, H Latrache
BACKGROUND: Food safety has become an absolute necessity in all countries. As a result, Morocco has taken several measures and actions to develop food safety and food-borne disease control. OBJECTIVE: This study aimed to highlight the level of improvement in the quality assurance of meat and meat products in Morocco. METHOD: It is based on a non-exhaustive review of the regulatory texts governing food safety in the country, as well as a statistical study on establishments of meat and meat products adopting a self-checking system and approved by the National Office of Sanitary Safety of Food...
March 12, 2018: Revue D'épidémiologie et de Santé Publique
Arnaud Boyer, Eddy Pasquier, Pascale Tomasini, Joseph Ciccolini, Laurent Greillier, Nicolas Andre, Fabrice Barlesi, Celine Mascaux
Drug repurposing is the use of known drugs for new indications. Malignant pleural mesothelioma (MPM) is a rare cancer with a poor prognosis. So far, few treatments have been approved in this disease. However, its incidence is expected to increase significantly, particularly in developing countries. Consequently, drug repurposing appears as an attractive strategy for drug development in MPM, since the known pharmacology and safety profile based on previous approvals of repurposed drugs allows for faster time-to-market for patients and lower treatment cost...
March 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
Wendi Gosliner, Daniel M Brown, Betty C Sun, Gail Woodward-Lopez, Patricia B Crawford
OBJECTIVE: To assess produce availability, quality and price in a large sample of food stores in low-income neighbourhoods in California. DESIGN: Cross-sectional statewide survey. SETTING: Between 2011 and 2015, local health departments assessed store type, WIC (Supplemental Nutrition Program for Women, Infants, and Children)/SNAP (Supplemental Nutrition Assistance Program) participation, produce availability, quality and price of selected items in stores in low-income neighbourhoods...
March 15, 2018: Public Health Nutrition
Anders Anell, Margareta Dackehag, Jens Dietrichson
BACKGROUND: Providing equal access to health care is an important objective in most health care systems. It is especially pertinent in systems like the Swedish primary care market, where private providers are free to establish themselves in any part of the country. To improve equity in access to care, 15 out 21 county councils in Sweden have implemented risk-adjusted capitation based on the Care Need Index, which increases capitation to primary care centers with a large share of patients with unfavorable socioeconomic and demographic characteristics...
March 14, 2018: BMC Health Services Research
Luana Romão Nogueira, Mariane de Mello Fontanelli, Breno Souza de Aguiar, Marcelo Antunes Failla, Alex Antonio Florindo, Ligia Vizeu Barrozo, Moisés Goldbaum, Chester Luiz Galvão Cesar, Maria Cecilia Goi Porto Alves, Regina Mara Fisberg
Food environment and income act as determinants of diet, and consequently, of the consumption of fruits and vegetables. The objective of this study is to investigate the association between fruit and vegetable consumption, income, and street market density in adolescents living in São Paulo, Brazil. Data from 521 adolescents (12 to 19 years) participating in the 2015 Health Survey of São Paulo were used. Buffers (500, 1000, and 1500 m) were drawn around the households and the street markets were counted in each zone...
March 14, 2018: International Journal of Environmental Research and Public Health
Stephen Poyer, Anne Musuva, Nancy Njoki, Robi Okara, Andrea Cutherell, Dana Sievers, Cristina Lussiana, Dorothy Memusi, Rebecca Kiptui, Waqo Ejersa, Stephanie Dolan, Nicole Charman
BACKGROUND: Private sector availability and use of malaria rapid diagnostic tests (RDTs) lags behind the public sector in Kenya. Increasing channels through which quality malaria diagnostic services are available can improve access to testing and help meet the target of universal diagnostic testing. Registered pharmacies are currently not permitted to perform blood tests, and evidence of whether malaria RDTs can be used by non-laboratory private providers in line with the national malaria control guidelines is required to inform ongoing policy discussions in Kenya...
March 13, 2018: Malaria Journal
Driss Berdaï, Florence Thomas-Delecourt, Karine Szwarcensztein
Early market access of health products is associated with a larger number of requests for information by the health authorities. Compared with these expectations, the growing expansion of health databases represents an opportunity for responding to questions raised by the authorities. The computerised nature of the health system provides numerous sources of data, and first and foremost medical/administrative databases such as the French National Inter-Scheme Health Insurance Information System (SNIIRAM) database...
December 30, 2017: Thérapie
Laura Jane Bry, Tommy Chou, Elizabeth Miguel, Jonathan S Comer
Anxiety disorders are collectively the most prevalent mental health problems affecting youth. To increase the reach of mental health care, recent years have seen increasing enthusiasm surrounding mobile platforms for expanding treatment delivery options. Apps developed in academia and supported in clinical trials are slow to reach the consumer marketplace. Meanwhile, proliferation of industry-developed apps on consumer marketplaces has been high. The present study analyzed content within mobile products prominently marketed toward consumers for anxiety in youth...
March 2018: Behavior Therapy
Bano Mehdi, Bernhard Lehner, Ralf Ludwig
To develop meaningful land use scenarios, drivers that affect changes in the landscape are required. In this study, driving factors that influence farmers to change crops on their farm were determined. A questionnaire was administered to four independent groups of farmers who identified and ranked influencing factors pertaining to their choices of crops. The farmers were located in two mid-latitude agricultural watersheds (in Germany and Canada). The ranked influencing factors were used to develop a "farmer driven" scenario to 2040 in both watersheds...
March 8, 2018: Science of the Total Environment
Rodrigo Postigo, Sabine Brosch, Jim Slattery, Anja van Haren, Jean-Michel Dogné, Xavier Kurz, Gianmario Candore, Francois Domergue, Peter Arlett
The analysis of safety data from spontaneous reporting systems has a proven value for the detection and analysis of the risks of medicines following their placement on the market and use in medical practice. EudraVigilance is the pharmacovigilance database to manage the collection and analysis of suspected adverse reactions to medicines authorised in the European Economic Area. EudraVigilance first operated in December 2001, with access to the database being governed by the EudraVigilance access policy. We performed a literature search including data up to December 2016 to demonstrate how the data from EudraVigilance has been used in scientific publications...
March 9, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Rajeev K Varshney, Mahendar Thudi, Manish K Pandey, Francois Tardieu, Chris Ojiewo, Vincent Vadez, Anthony M Whitbread, Kadambot H M Siddique, Henry T Nguyen, Peter S Carberry, David Bergvinson
Grain legumes form an important component of the human diet, feed for livestock and replenish soil fertility through biological nitrogen fixation. Globally, the demand for food legumes is increasing as they complement cereals in protein requirements and possess a high percentage of digestible protein. Climate change has enhanced the frequency and intensity of drought stress that is posing serious production constraints, especially in rainfed regions where most legumes are produced. Genetic improvement of legumes, like other crops, is mostly based on pedigree and performance-based selection over the last half century...
March 5, 2018: Journal of Experimental Botany
Dima Faour-Klingbeil, Ewen C D Todd
Food safety standards are a necessity to protect consumers' health in today's growing global food trade. A number of studies have suggested safety standards can interrupt trade, bringing financial and technical burdens on small as well as large agri-food producers in developing countries. Other examples have shown that economical extension, key intermediaries, and funded initiatives have substantially enhanced the capacities of growers in some countries of the Middle East and North Africa (MENA) region to meet the food safety and quality requirements, and improve their access to international markets...
March 3, 2018: Foods (Basel, Switzerland)
Sergio I Prada, Victoria E Soto, Tatiana S Andia, Claudia P Vaca, Álvaro A Morales, Sergio R Márquez, Alejandro Gaviria
Background: High pharmaceutical expenditure is one of the main concerns for policymakers worldwide. In Colombia, a middle-income country, outpatient prescription represents over 10% of total health expenditure in the mandatory benefits package (POS), and close to 90% in the complementary government fund (No POS). In order to control expenditure, since 2011, the Ministry of Health introduced price caps on inpatient drugs reimbursements by active ingredient. By 2013, more than 400 different products, covering 80% of public pharmaceutical expenditure were controlled...
2018: Cost Effectiveness and Resource Allocation: C/E
Hamid Khazaei, Michael Fedoruk, Carolyn T Caron, Albert Vandenberg, Kirstin E Bett
The dimensions of lentil ( Medik.) seeds are important quality parameters that are major determinants of market preference, cooking time, and post-harvest milling quality. Knowledge of the genetic control of traits related to seed dimensions would be useful for crop improvement. The principal aim of this study was to identify single nucleotide polymorphism (SNP) markers linked to genes that control seed diameter, seed thickness, and seed plumpness. Association mapping analysis with SNP markers was used to study the seed dimensions of 138 diverse cultivated lentil accessions grown at two locations in Saskatchewan, Canada, in 2011 and 2012...
March 2018: Plant Genome
Shinya Takemoto
 In recent years, as the market has seen the appearance of innovative medical products with novel mechanisms of action, adverse reactions that cannot be expected from the approved product label are being detected in the postmarketing phase. It is increasingly important to undertake timely product label updates and other drug safety measures through the monitoring, early detection, and reporting of adverse reactions. In 2013, the risk management plan (RMP) system was introduced in Japan. An RMP documents efforts to ensure the safety of a medical product, and sharing the RMP with stakeholders results in enhanced postmarketing safety measures...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
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