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https://www.readbyqxmd.com/read/28343770/epidemiology-of-varicella-in-haidian-district-beijing-china-2007-2015
#1
Jiye Fu, Chu Jiang, Juguang Wang, Fengxia Zhao, Tianwei Ma, Rujing Shi, Yanhong Zhao, Xianfeng Zhang
BACKGROUND: 1-Dose varicella vaccination was recommended for children in Beijing before November 2012. To further control school-based outbreaks and decrease incidence, a 2-dose vaccination was implemented in 2013. We described the varicella epidemiology and assessed impact of the 2-dose vaccination in Haidian district, Beijing, 2007-2015. METHODS: We examined the estimated incidence and disease characteristics of varicella during 2007-2015 and obtained the 1-dose vaccination coverage for children born during 2005-2013...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28342711/epidemiological-profile-and-vaccination-coverage-in-splenectomy-patients-in-a-health-area-of-murcia-1993-2012
#2
Yolanda Molina-Salas, Francisco José Romera-Guirado, Jaime Jesús Pérez-Martín, María Nieves Peregrín-González, David Góngora-Soria
OBJECTIVE: Splenectomy patients have a high risk of suffering severe infections, many of them preventable by vaccination. The aim of the study was to analyse the clinical epidemiological characteristics and vaccine coverage of these patients in Health Area III of the Region of Murcia. METHOD: A cross-sectional study was conducted on a population of patients that were splenectomised during the period 1993-2012, according to the Register of the Basic Minimum Data Set...
March 22, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28341014/live-pertussis-vaccines-will-they-protect-against-carriage-and-spread-of-pertussis
#3
REVIEW
C Locht
Pertussis is a severe respiratory disease that can be fatal in young infants. Its main aetiological agent is the Gram-negative micro-organism Bordetella pertussis. Vaccines against the disease have been in use since the 1950s, and global vaccination coverage has now reached more than 85%. Nevertheless, the disease has not been controlled in any country, and has even made a spectacular come-back in the industrialized world, where the first-generation whole-cell vaccines have been replaced by the more recent, less reactogenic, acellular vaccines...
December 1, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28340974/herpes-zoster-vaccine-coverage-in-older-adults-in-the-u-s-2007-2013
#4
Dongmu Zhang, Kelly Johnson, Chrisann Newransky, Camilo J Acosta
INTRODUCTION: This study aimed to assess the coverage of herpes zoster (HZ) vaccine among a large cohort of insured individuals aged ≥50 years from 2007 to 2013, and to determine the factors associated with being vaccinated for adults aged ≥60 years. METHODS: This was a retrospective, observational study using the MarketScan® database conducted in 2015. The study population was U.S. adults aged ≥60 years during 2007-2013 and 50-59 years during 2011-2013. The claims of each eligible subject were evaluated post-index date to assess HZ vaccine uptake...
January 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28338902/assessment-of-the-status-of-measles-elimination-in-the-united-states-2001-2014
#5
Paul A Gastañaduy, Prabasaj Paul, Amy Parker Fiebelkorn, Susan B Redd, Ben A Lopman, Manoj Gambhir, Gregory S Wallace
We assessed the status of measles elimination in the United States using outbreak notification data. Measles transmissibility was assessed by estimation of the reproduction number, R, the average number of secondary cases per infection, using 4 methods; elimination requires maintaining R at <1. Method 1 estimates R as 1 minus the proportion of cases that are imported. Methods 2 and 3 estimate R by fitting a model of the spread of infection to data on the sizes and generations of chains of transmission, respectively...
March 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28336382/migration-and-infectious-diseases
#6
REVIEW
Francesco Castelli, Giorgia Sulis
BACKGROUND: Infectious diseases still represent an important cause of morbidity and mortality among foreign-born individuals. The rising migration flows towards Europe throughout the last few years are raising renewed concerns about management issues and the potential associated risk for the native population. AIMS: To discuss the health implications and challenges related to the four phases of migration, from first arrival to stable resettlement. SOURCES: Scientific literature and relevant statistical reports...
March 20, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28334397/does-post-implementation-vaccine-effectiveness-data-support-pre-implementation-predictions-of-4cmenb-utility
#7
Jamie Findlow, Ray Borrow
Meningococcal serogroup B vaccines have been licensed on the basis of safety and immunogenicity data without efficacy studies. Establishing the breadth of coverage of these new vaccines has proved difficult and relied on correlates of protection such as serum bactericidal antibody and a novel assays such as the Meningococcal Antigen Typing System. The demonstration of the effectiveness of 4CMenB in a reduced infant dose schedule together with detailed phenotypic and genotypic information gained from isolates and sera from cases of invasive MenB disease in vaccine eligible infants will enable a re-evaluation of our knowledge of correlates of protection...
March 8, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28331981/vaccination-in-oncology-practice-and-predictors
#8
Ali Alkan, Ebru Karcı, Arzu Yaşar, Gülseren Tuncay, Elif Berna Köksoy, Muslih Ürün, Filiz Çay Şenler, Ahmet Demirkazık, Güngör Utkan, Hakan Akbulut, Yüksel Ürün
PURPOSE: Despite, vaccination is a highly effective and widely recommended for prevention of certain infections, vaccination coverage is very low. The purposes of this study were to evaluate the attitudes of medical oncologists towards vaccination and to identify predictors of intention to recommend vaccination in patients with cancer. METHODS: A structured questionnaire is formed to evaluate the daily practice of vaccination. Turkish medical oncologists were invited to this study via email, SMS, or phone call...
March 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28329831/racial-ethnic-disparities-in-influenza-and-pneumococcal-vaccinations-among-nursing-home-residents-a-systematic-review
#9
Jasmine L Travers, Krista L Schroeder, Thomas E Blaylock, Patricia W Stone
This systematic review analyzes research examining racial/ethnic disparities in influenza and pneumococcal vaccination coverage between White and racial/ethnic minority (Black and Hispanic) nursing home residents. A review of the literature for years 1966-2014 using Medline, Web of Science, and PubMed was conducted. The Epidemiological Appraisal Instrument was used to appraise the quality of the 13 included studies. Overall, articles were strong in reporting and data analysis, but weak in sample selection and measurement quality...
January 21, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328809/infectious-diseases-prevalence-vaccination-coverage-and-diagnostic-challenges-in-a-population-of-internationally-adopted-children-referred-to-a-tertiary-care-children-s-hospital-from-2009-to-2015
#10
Sara Sollai, Francesca Ghetti, Leila Bianchi, Maurizio de Martino, Luisa Galli, Elena Chiappini
Infectious diseases are common in internationally adopted children (IAC).With the objective to evaluate infectious diseases prevalence in a large cohort of IAC and to explore possible risk factors for tuberculosis (TB) and parasitic infections, clinical and laboratory data at first screening visit of all IAC (<18 years) consecutively referred to our Center in 2009 to 2015 were collected and analyzed.In total, 1612 children (median age: 5.40 years; interquartile range: 3.00-7.90) were enrolled, 123/1612 (7...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328521/human-papillomavirus-first-and-second-generation-vaccines-current-status-and-future-directions
#11
Somayeh Pouyanfard, Martin Müller
It has been more than 10 years that the first prophylactic papillomavirus vaccine became available, although distribution has been mainly limited to the more affluent countries. The first two vaccines have been a great success, hundreds of millions of women and a much smaller number of men have been vaccinated ever since. In a few countries with high vaccination coverage, in particular Australia but also parts of Great Britain and others, clinical impact of vaccination programs is already visible and there are indications for herd immunity as well...
March 22, 2017: Biological Chemistry
https://www.readbyqxmd.com/read/28327987/pssmhcpan-a-novel-pssm-based-software-for-predicting-class-i-peptide-hla-binding-affinity
#12
Geng Liu, Dongli Li, Zhang Li, Si Qiu, Wenhui Li, Cheng-Chi Chao, Naibo Yang, Handong Li, Zhen Cheng, Xin Song, Le Cheng, Xiuqing Zhang, Jian Wang, Huanming Yang, Kun Ma, Yong Hou, Bo Li
Background: Predicting peptides binding affinity with human leukocyte antigen (HLA) is a crucial step in developing powerful antitumor vaccine for cancer immunotherapy. Currently available methods work quite well in predicting peptide binding affinity with HLA alleles such as HLA-A*0201, HLA-A*0101, and HLA-B*0702 in terms of sensitivity and specificity. However, quite a few types of HLA alleles that are present in majority of human populations including HLA-A*0202, HLA-A*0203, HLA-A*6802, HLA-B*5101, HLA-B*5301, HLA-B*5401 and HLA-B*5701 still cannot be predicted with satisfactory accuracy using currently available methods...
March 15, 2017: GigaScience
https://www.readbyqxmd.com/read/28321367/evaluation-of-procedures-for-typing-of-group-b-streptococcus-a-retrospective-study
#13
Hans-Christian Slotved, Steen Hoffmann
BACKGROUND: This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the Lancefield precipitation test (LP test). Furthermore, the genotype distribution of phenotypically non-typable (NT) GBS isolates is presented. We also raise the awareness, that the difference in typing results obtained by phenotypical methods and genotype based methods may have implications on vaccine surveillance in case a GBS vaccine is introduced...
2017: PeerJ
https://www.readbyqxmd.com/read/28320938/effectiveness-of-unaids-targets-and-hiv-vaccination-across-127-countries
#14
Jan Medlock, Abhishek Pandey, Alyssa S Parpia, Amber Tang, Laura A Skrip, Alison P Galvani
The HIV pandemic continues to impose enormous morbidity, mortality, and economic burdens across the globe. Simultaneously, innovations in antiretroviral therapy, diagnostic approaches, and vaccine development are providing novel tools for treatment-as-prevention and prophylaxis. We developed a mathematical model to evaluate the added benefit of an HIV vaccine in the context of goals to increase rates of diagnosis, treatment, and viral suppression in 127 countries. Under status quo interventions, we predict a median of 49 million [first and third quartiles 44M, 58M] incident cases globally from 2015 to 2035...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28320592/facilitators-and-barriers-of-parental-attitudes-and-beliefs-toward-school-located-influenza-vaccination-in-the-united-states-systematic-review
#15
REVIEW
Gloria J Kang, Rachel K Culp, Kaja M Abbas
The study objective was to identify facilitators and barriers of parental attitudes and beliefs toward school-located influenza vaccination in the United States. In 2009, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention expanded their recommendations for influenza vaccination to include school-aged children. We conducted a systematic review of studies focused on facilitators and barriers of parental attitudes toward school-located influenza vaccination in the United States from 1990 to 2016...
March 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28319453/prenatal-vaccination-education-intervention-improves-both-the-mothers-knowledge-and-children-s-vaccination-coverage-evidence-from-randomized-controlled-trial-from-eastern-china
#16
Yu Hu, Yaping Chen, Ying Wang, Quanwei Song, Qian Li
OBJECTIVES: To verify the effectiveness of prenatal vaccination education intervention on improving mother's vaccination knowledge and child's vaccination status in Zhejiang province, eastern China. METHODS: Pregnant women with ≥ 12 gestational weeks were recruited and randomly assigned into the intervention group and the control group. The intervention group were given a vaccination education session while the control group were not. Two round surveys were performed before and 3 months after the intervention...
February 21, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28318771/cross-protection-to-new-drifted-influenza-a-h3-viruses-and-prevalence-of-protective-antibodies-to-seasonal-influenza-during-2014-in-portugal
#17
Raquel Guiomar, Susana Pereira da Silva, Patrícia Conde, Paula Cristóvão, Ana Carina Maia, Pedro Pechirra, Ana Paula Rodrigues, Baltazar Nunes, Luís Milho, Ana Paula Coelho, Aida Fernandes, Paula Caseiro, Fernando Rodrigues, Lurdes Correia, João Pereira-Vaz, Sofia Almeida, Paula Branquinho, Rita Côrte-Real, Regina Viseu, Maria João Peres, Raquel Sanches, Filipa Dantas, Ludovina Freitas, Graça Andrade, Manuel Maurílio, Filomena Caldeira, Rita Cabral Veloso, Luisa Mota-Vieira, Marta Soares, Ana Rita Couto, Jácome Bruges-Armas, Rita Mouro Pinto, Joana Sobrinho Simões, Maria do Rosário Costa, João Tiago Guimarães, Luís Martins, Mário Cunha
INTRODUCTION: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portuguese population. MATERIALS AND METHODS: We developed a cross-sectional study based on a convenience sample of 626 sera collected during June 2014, covering all age groups, both gender and all administrative health regions of Portugal...
March 15, 2017: Vaccine
https://www.readbyqxmd.com/read/28315129/influenza-vaccination-coverage-among-polish-patients-with-chronic-diseases
#18
Aneta Nitsch-Osuch, Izabella Gołębiak, Dorota Wyszkowska, Renata Rosińska, Lidia Kargul, Bożena Szuba, Piotr Tyszko, Lidia Brydak
Patients at a high-risk of severe influenza, because of their underlying health disorders, are recommended to receive a seasonal influenza vaccination. In Poland, influenza coverage rate in the general population is very low (3.4 %). However, there is little known about the coverage rate among high-risk patients. The aim of this study was to describe a general knowledge, perception, and influenza vaccination coverage rate among Polish patients with enhanced risk for influenza. We conducted a self-reported survey among 500 patients with chronic disorders: 120 pulmonary, 80 hemodialyzed, 100 thyroid cancer, and 200 cardiovascular patients...
March 18, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28306717/barriers-to-dog-rabies-vaccination-during-an-urban-rabies-outbreak-qualitative-findings-from-arequipa-peru
#19
Ricardo Castillo-Neyra, Joanna Brown, Katty Borrini, Claudia Arevalo, Michael Z Levy, Alison Buttenheim, Gabrielle C Hunter, Victor Becerra, Jere Behrman, Valerie A Paz-Soldan
BACKGROUND: Canine rabies was reintroduced to the city of Arequipa, Peru in March 2015. The Ministry of Health has conducted a series of mass dog vaccination campaigns to contain the outbreak, but canine rabies virus transmission continues in Arequipa's complex urban environment, putting the city's 1 million inhabitants at risk of infection. The proximate driver of canine rabies in Arequipa is low dog vaccination coverage. Our objectives were to qualitatively assess barriers to and facilitators of rabies vaccination during mass campaigns, and to explore strategies to increase participation in future efforts...
March 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28303826/prevalence-of-pneumococcal-serotypes-in-adults-%C3%A2-50-years-of-age
#20
Chand Wattal, Neeraj Goel, S P Byotra
CONTEXT: Currently, majority of studies on antibiotic resistance and serotype prevalence in Streptococcus pneumoniae are in paediatric population and there is limited epidemiologic data pertaining to elderly Indian population. AIMS: This study was undertaken to assess antibiotic resistance pattern and the coverage of the polysaccharide vaccine 23 (PPV23) in the elderly population. SETTINGS AND DESIGN: This was a prospective 2-year pneumococcal surveillance study in patients with community-acquired pneumococcal infections of ≥50 years' age group on fifty isolates of S...
January 2017: Indian Journal of Medical Microbiology
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