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Contrast enhanced mammography

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https://www.readbyqxmd.com/read/28723585/clinical-utility-of-contrast-enhanced-spectral-mammography-as-an-adjunct-for-tomosynthesis-detected-architectural-distortion
#1
Bhavika K Patel, Michelle E Naylor, Heidi E Kosiorek, Yania M Lopez-Alvarez, Adrian M Miller, Victor J Pizzitola, Barbara A Pockaj
OBJECTIVE: Supplement tomosynthesis-detected architectural distortions (AD) with CESM to better characterize malignant vs benign lesions. METHODS: Retrospective review CESM prior to biopsied AD. Pathology: benign, radial scar, or malignant. RESULTS: 49 lesions (45 patients). 29 invasive cancers, 1 DCIS (range, 0.4-4.7cm); 9 radial scars; 10 benign. 37 (75.5%) ADs had associated enhancement. PPV 78.4% (29/37), sensitivity 96.7% (29/30); specificity, 57...
July 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28688583/image-improvement-method-for-positron-emission-mammography
#2
Nikolai V Slavine, Stephen J Seiler, Roderick W McColl, Robert E Lenkinski
PURPOSE: To evaluate in clinical use a rapidly converging, efficient iterative deconvolution algorithm (RSEMD) for improving the quantitative accuracy of previously reconstructed breast images by a commercial positron emission mammography (PEM) scanner. MATERIALS AND METHODS: The RSEMD method was tested on imaging data from clinical Naviscan Flex Solo II PEM scanner. This method was applied to anthropomorphic like breast phantom data and patient breast images previously reconstructed with Naviscan software to determine improvements in image resolution, signal to noise ratio (SNR) and contrast to noise ratio (CNR)...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28681390/a-deep-feature-fusion-methodology-for-breast-cancer-diagnosis-demonstrated-on-three-imaging-modality-datasets
#3
Natalia Antropova, Benjamin Q Huynh, Maryellen L Giger
Deep learning methods for radiomics/computer-aided diagnosis (CADx) are often prohibited by small datasets, long computation time, and the need for extensive image preprocessing. We present a methodology that extracts and pools low- to mid-level features using a pre-trained convolutional neural network and fuses them with handcrafted radiomic features computed using conventional CADx methods. Our fusion-based method demonstrates significant improvements to previous breast cancer CADx methods across three clinical imaging modalities (dynamic contrast-enhanced MRI, full-field digital mammography, and ultrasound) in terms of predictive performance in the task of estimating lesion malignancy...
July 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28656455/malignancy-detection-on-mammography-using-dual-deep-convolutional-neural-networks-and-genetically-discovered-false-color-input-enhancement
#4
Philip Teare, Michael Fishman, Oshra Benzaquen, Eyal Toledano, Eldad Elnekave
Breast cancer is the most prevalent malignancy in the US and the third highest cause of cancer-related mortality worldwide. Regular mammography screening has been attributed with doubling the rate of early cancer detection over the past three decades, yet estimates of mammographic accuracy in the hands of experienced radiologists remain suboptimal with sensitivity ranging from 62 to 87% and specificity from 75 to 91%. Advances in machine learning (ML) in recent years have demonstrated capabilities of image analysis which often surpass those of human observers...
June 27, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28654337/newly-diagnosed-breast-cancer-comparison-of-contrast-enhanced-spectral-mammography-and-breast-mr-imaging-in-the-evaluation-of-extent-of-disease
#5
Stephanie A Lee-Felker, Leena Tekchandani, Mariam Thomas, Esha Gupta, Denise Andrews-Tang, Antoinette Roth, James Sayre, Guita Rahbar
Purpose To compare the diagnostic performances of contrast material-enhanced spectral mammography and breast magnetic resonance (MR) imaging in the detection of index and secondary cancers in women with newly diagnosed breast cancer by using histologic or imaging follow-up as the standard of reference. Materials and Methods This institutional review board-approved, HIPAA-compliant, retrospective study included 52 women who underwent breast MR imaging and contrast-enhanced spectral mammography for newly diagnosed unilateral breast cancer between March 2014 and October 2015...
June 26, 2017: Radiology
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#6
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
June 13, 2017: Radiology
https://www.readbyqxmd.com/read/28583631/repeated-surgeries-in-invasive-lobular-breast-cancer-with-preoperative-mri-role-of-additional-carcinoma-in-situ-and-background-parenchymal-enhancement
#7
H Preibsch, V Richter, S D Bahrs, V Hattermann, B M Wietek, G Bier, C Kloth, G Blumenstock, M Hahn, A Staebler, K Nikolaou, B Wiesinger
OBJECTIVES: Analysing the influence of additional carcinoma in situ (CIS) and background parenchymal enhancement (BPE) in preoperative MRI on repeated surgeries in patients with invasive lobular carcinoma (ILC) of the breast. METHODS: Retrospective analysis of 106 patients (mean age 58.6±9.9years) with 108 ILC. Preoperative tumour size as assessed by MRI, mammography and sonography was recorded and compared to histopathology. In contrast-enhanced MRI, the degree of BPE was categorised by two readers...
May 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28549292/globally-supported-radial-basis-function-based-collocation-method-for-evolution-of-level-set-in-mass-segmentation-using-mammograms
#8
Kanchan Lata Kashyap, Manish Kumar Bajpai, Pritee Khanna
Computer-aided detection systems play an important role for the detection of breast abnormalities using mammograms. Global segmentation of mass in mammograms is a complex process due to low contrast mammogram images, irregular shape of mass, speculated margins, and the presence of intensity variations of pixels. This work presents a new approach for mass detection in mammograms, which is based on the variational level set function. Mesh-free based radial basis function (RBF) collocation approach is employed for the evolution of level set function for segmentation of breast as well as suspicious mass region...
May 15, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28543761/experimental-characterization-of-a-direct-conversion-amorphous-selenium-detector-with-thicker-conversion-layer-for-dual-energy-contrast-enhanced-breast-imaging
#9
David A Scaduto, Olivier Tousignant, Wei Zhao
PURPOSE: Dual-energy contrast-enhanced imaging is being investigated as a tool to identify and localize angiogenesis in the breast, a possible indicator of malignant tumors. This imaging technique requires that x-ray images are acquired at energies above the k-shell binding energy of an appropriate radiocontrast agent. Iodinated contrast agents are commonly used for vascular imaging, and require x-ray energies greater than 33 keV. Conventional direct conversion amorphous selenium (a-Se) flat panel imagers for digital mammography show suboptimal absorption efficiencies at these higher energies...
May 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28541197/high-energy-resolution-hyperspectral-x-ray-imaging-for-low-dose-contrast-enhanced-digital-mammography
#10
Silvia Pani, Sarene Saifuddin, Filipa Ferreira, Nicholas Henthorn, Paul Seller, Paul Sellin, Philipp Stratmann, Matthew Veale, Matthew Wilson, Robert Cernik
Contrast-enhanced digital mammography (CEDM) is an alternative to conventional X-ray mammography for imaging dense breasts. However, conventional approaches to CEDM require a double exposure of the patient, implying higher dose and risk of incorrect image registration due to motion artifacts. A novel approach is presented, based on hyperspectral imaging, where a detector combining positional and high-resolution spectral information (in this case based on Cadmium Telluride) is used. This allows simultaneous acquisition of the two images required for CEDM...
May 18, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28457521/image-processing-can-cause-some-malignant-soft-tissue-lesions-to-be-missed-in-digital-mammography-images
#11
L M Warren, M D Halling-Brown, P T Looney, D R Dance, M G Wallis, R M Given-Wilson, L Wilkinson, R McAvinchey, K C Young
AIM: To investigate the effect of image processing on cancer detection in mammography. METHODS AND MATERIALS: An observer study was performed using 349 digital mammography images of women with normal breasts, calcification clusters, or soft-tissue lesions including 191 subtle cancers. Images underwent two types of processing: FlavourA (standard) and FlavourB (added enhancement). Six observers located features in the breast they suspected to be cancerous (4,188 observations)...
April 27, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28453516/on-a-fractional-order-calculus-model-in-diffusion-weighted-breast-imaging-to-differentiate-between-malignant-and-benign-breast-lesions-detected-on-x-ray-screening-mammography
#12
Sebastian Bickelhaupt, Franziska Steudle, Daniel Paech, Anna Mlynarska, Tristan Anselm Kuder, Wolfgang Lederer, Heidi Daniel, Martin Freitag, Stefan Delorme, Heinz-Peter Schlemmer, Frederik Bernd Laun
OBJECTIVE: To evaluate a fractional order calculus (FROC) model in diffusion weighted imaging to differentiate between malignant and benign breast lesions in breast cancer screening work-up using recently introduced parameters (βFROC, DFROC and μFROC). MATERIALS AND METHODS: This retrospective analysis within a prospective IRB-approved study included 51 participants (mean 58.4 years) after written informed consent. All patients had suspicious screening mammograms and indication for biopsy...
2017: PloS One
https://www.readbyqxmd.com/read/28432828/quantitative-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors-a-feasibility-study
#13
Huanjun Ding, Sabee Molloi
PURPOSE: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. MATERIALS AND METHODS: A computer simulation model was developed to evaluate the performance of a photon-counting spectral mammography system in the application of contrast-enhanced spectral mammography. A figure-of-merit (FOM), which was defined as the decomposed iodine signal-to-noise ratio (SNR) with respect to the square root of the mean glandular dose (MGD), was chosen to optimize the imaging parameters, in terms of beam energy, splitting energy, and pre-filtrations for breasts of various thicknesses and densities...
April 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28379734/potential-cost-savings-of-contrast-enhanced-digital-mammography
#14
Bhavika K Patel, Richard J Gray, Barbara A Pockaj
OBJECTIVE: The purpose of this article is to discuss whether the sensitivity and specificity of contrast-enhanced digital mammography (CEDM) render it a viable diagnostic alternative to breast MRI. CONCLUSION: That CEDM couples low-energy images (comparable to the diagnostic quality of standard mammography) and subtracted contrast-enhanced mammograms makes it a cost-effective modality for routine screening. CEDM may serve as a realistic substitute for the more costly breast MRI...
April 5, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28363948/false-negative-contrast-enhanced-spectral-mammography-use-of-more-than-one-imaging-modality-and-application-of-the-triple-test-avoids-misdiagnosis
#15
Donna Taylor, Susan O'Hanlon, Bruce Latham
A 50-year-old woman presented with chest tenderness. On examination, both breasts were lumpy. Bilateral mammography showed heterogeneously dense parenchyma, with possible stromal distortion laterally on the right at the 0900 position. On ultrasound (US), a corresponding 13×9×10 mm irregular hypoechoic mass with internal vascularity was noted and both breasts had a complex heterogeneous fibroglandular background pattern. US-guided core biopsy with marker clip insertion was performed with the diagnosis of a grade 2 invasive ductal carcinoma (IDC)...
March 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28318506/assessment-of-disease-extent-on-contrast-enhanced-mri-in-breast-cancer-detected%C3%A2-at-digital-breast-tomosynthesis-versus%C3%A2-digital-mammography-alone
#16
COMPARATIVE STUDY
A V Chudgar, E F Conant, S P Weinstein, B M Keller, M Synnestvedt, P Yamartino, E S McDonald
AIM: To compare the utility of breast magnetic resonance imaging (MRI) in determining the extent of disease in patients with newly diagnosed breast cancer detected on combination digital breast tomosynthesis (DBT) versus digital screening mammography (DM). MATERIALS AND METHODS: Review of 24,563 DBT-screened patients and 10,751 DM-screened patients was performed. Two hundred and thirty-five DBT patients underwent subsequent MRI examinations; 82 to determine extent of disease after newly diagnosed breast cancer...
July 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28299890/a-case-of-adenomyoepithelioma-of-the-breast-showing-strong-uptake-of-18-f-fluorodeoxyglucose-on-a-positron-emission-tomography
#17
Takaaki Oba, Kazuma Maeno, Mayu Ono, Asumi Iesato, Tokiko Ito, Toshiharu Kanai, Yasuhiro Mochizuki, Ken-Ichi Ito, Akihiko Yoshizawa, Fumiyoshi Takayama
An adenomyoepithelioma of the breast is a rare tumor characterized by biphasic proliferation of both epithelial and myoepithelial cells. This tumor is generally considered as a benign neoplasm, and there are few reports describing the imaging features of this tumor through (18) F-fluorodeoxyglucose positron emission tomography (FDG-PET). Here, we report a case of an adenomyoepithelioma that showed strong uptake of FDG on PET similar to that observed with a malignant tumor. A 73-year-old woman presented to our hospital with a 3...
March 2017: Breast Journal
https://www.readbyqxmd.com/read/28284000/a-method-for-microcalcifications-detection-in-breast-mammograms
#18
Abbas H Hassin Alasadi, Ahmed Kadem Hamed Al-Saedi
Breast cancer is the most cause of death for women above age 40 around the world. In this paper, we propose a method to detect microcalcifications in digital mammography images using two-dimensional Discrete Wavelets Transform and image enhancement techniques for removing noise as well as to get a better contrast. The initial step is applying a preprocessing techniques to improve the edge of the breast and then segmentation process (Region of interest) for eliminating some regions in the image, which are not useful for the mammography interpretation...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28267545/fourier-domain-image-fusion-for-differential-x-ray-phase-contrast-breast-imaging
#19
Eduardo Coello, Jonathan I Sperl, Dirk Bequé, Tobias Benz, Kai Scherer, Julia Herzen, Anikó Sztrókay-Gaul, Karin Hellerhoff, Franz Pfeiffer, Cristina Cozzini, Susanne Grandl
X-Ray Phase-Contrast (XPC) imaging is a novel technology with a great potential for applications in clinical practice, with breast imaging being of special interest. This work introduces an intuitive methodology to combine and visualize relevant diagnostic features, present in the X-ray attenuation, phase shift and scattering information retrieved in XPC imaging, using a Fourier domain fusion algorithm. The method allows to present complementary information from the three acquired signals in one single image, minimizing the noise component and maintaining visual similarity to a conventional X-ray image, but with noticeable enhancement in diagnostic features, details and resolution...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28209330/role-of-magnetic-resonance-imaging-in-detection-of-pathologic-complete-remission-in-breast-cancer-patients-treated-with-neoadjuvant-chemotherapy-a-meta-analysis
#20
REVIEW
Yan-Lin Gu, Si-Meng Pan, Jie Ren, Zhi-Xue Yang, Guo-Qin Jiang
Pathologic complete remission after neoadjuvant chemotherapy has a role in guiding the management of breast cancer. The present meta-analysis examined the accuracy of contrast-enhanced magnetic resonance imaging (CE-MRI) and diffusion-weighted magnetic resonance imaging (DW-MRI) in detecting the response to neoadjuvant chemotherapy and compared CE-MRI with ultrasonography, mammography, and positron emission tomography/computed tomography (PET/CT). Medical subject heading terms and related keywords were searched to generate a compilation of eligible studies...
January 11, 2017: Clinical Breast Cancer
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