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Contrast enhanced mammography

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https://www.readbyqxmd.com/read/29344009/evaluation-of-nipple-aspirate-fluid-as-a-diagnostic-tool-for-early-detection-of-breast-cancer
#1
REVIEW
Sadr-Ul Shaheed, Catherine Tait, Kyriacos Kyriacou, Richard Linforth, Mohamed Salhab, Chris Sutton
There has been tremendous progress in detection of breast cancer in postmenopausal women, resulting in two-thirds of women surviving more than 20 years after treatment. However, breast cancer remains the leading cause of cancer-related deaths in premenopausal women. Breast cancer is increasing in younger women due to changes in life-style as well as those at high risk as carriers of mutations in high-penetrance genes. Premenopausal women with breast cancer are more likely to be diagnosed with aggressive tumours and therefore have a lower survival rate...
2018: Clinical Proteomics
https://www.readbyqxmd.com/read/29317041/contrast-enhanced-spectral-mammography-a-review
#2
Bhavika K Patel, M B I Lobbes, John Lewin
Contrast-enhanced spectral mammography (CESM) provides low-energy 2D mammographic images comparable to standard digital mammography and a post-contrast recombined image to assess tumor neovascularity similar to magnetic resonance imaging (MRI). The utilization of CESM in the United States is currently low but could increase rapidly given many potential indications for clinical use. This article discusses historical background and literature review of indications and diagnostic accuracy of CESM to date. CESM is a growing technique for breast cancer detection and diagnosis that has levels of sensitivity and specificity on par with contrast-enhanced breast MRI...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317035/deciphering-the-breast-density-inform-law-movement-implications-for-practice
#3
Sean D Raj, Valerie Fein-Zachary, Priscilla J Slanetz
Although dense breast tissue is a normal and routine finding on screening mammography, dense breast tissue is associated with an independent increased risk for breast cancer. It is well known that screening mammography has a decreased sensitivity for cancer detection in women with dense breasts. Over the past decade, there has been increased interest generated among patients, physicians, and legislators regarding how best to screen dense-breasted women culminating in 2009 with the passage of a breast density notification law in Connecticut...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317032/newer-technologies-in-breast-cancer-imaging-dedicated-cone-beam-breast-computed-tomography
#4
Avice M O'Connell, Andrew Karellas, Srinivasan Vedantham, Daniel T Kawakyu-O'Connor
Dedicated breast computed tomography (CT) is the latest in a long history of breast imaging techniques dating back to the 1960s. Breast imaging is performed both for cancer screening as well as for diagnostic evaluation of symptomatic patients. Dedicated breast CT received US Food and Drug Administration approval for diagnostic use in 2015 and is slowly gaining recognition for its value in diagnostic 3-dimensional imaging of the breast, and also for injected contrast-enhanced imaging applications. Conventional mammography has known limitations in sensitivity and specificity, especially in dense breasts...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29279165/computer-aided-diagnosis-of-contrast-enhanced-spectral-mammography-a-feasibility-study
#5
Bhavika K Patel, Sara Ranjbar, Teresa Wu, Barbara A Pockaj, Jing Li, Nan Zhang, Mark Lobbes, Bin Zhang, J Ross Mitchell
OBJECTIVE: To evaluate whether the use of a computer-aided diagnosis-contrast-enhanced spectral mammography (CAD-CESM) tool can further increase the diagnostic performance of CESM compared with that of experienced radiologists. MATERIALS AND METHODS: This IRB-approved retrospective study analyzed 50 lesions described on CESM from August 2014 to December 2015. Histopathologic analyses, used as the criterion standard, revealed 24 benign and 26 malignant lesions. An expert breast radiologist manually outlined lesion boundaries on the different views...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29273223/personalised-screening-is-this-the-way-forward
#6
REVIEW
F J Gilbert, A Selamoglu
Screening with mammography has been implemented in many countries across the world with most offering 2-yearly examinations between the ages of 50-69 years. Robust modelling tools that include breast density and single nucleotide polymorphisms (SNPs) have been developed to predict which women are most likely to develop breast cancer. Mammographic sensitivity is poor in women with the densest category of breast tissue, and even women with heterogeneously dense tissue may benefit from additional supplemental imaging...
December 19, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29221721/factors-affecting-the-precision-of-lesion-sizing-with-contrast-enhanced-spectral-mammography
#7
M Del Mar Travieso-Aja, P Naranjo-Santana, C Fernández-Ruiz, W Severino-Rondón, D Maldonado-Saluzzi, M Rodríguez Rodríguez, V Vega-Benítez, O P Luzardo
AIM: To evaluate the precision of the pre-surgical measurement of the size of breast cancer by contrast-enhanced spectral mammography (CESM). MATERIAL AND METHODS: This was a retrospective study of 204 breast cancers. Variables related to tumour biology and anthropometric variables were recorded and considered when evaluating the efficacy of CESM in predicting tumour size. Microscopic measurement of the largest diameter of the tumour at pathology was chosen as the reference standard...
December 5, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29190656/mri-for-the-assessment-of-malignancy-in-bi-rads-4-mammographic-microcalcifications
#8
Barbara Bennani-Baiti, Matthias Dietzel, Pascal A Baltzer
PURPOSE: Assess the performance of breast MRI to diagnose breast cancer in BI-RADS 4 microcalcifications detected by mammography. MATERIALS AND METHODS: This retrospective, IRB-approved study included 248 consecutive contrast-enhanced breast MRI (1.5T, protocol in accordance with EUSOBI recommendations) performed to further diagnose BI-RADS 4 microcalcifications detected at mammography during a 3-year period. Standard of reference had to be established by histopathology...
2017: PloS One
https://www.readbyqxmd.com/read/29190227/potential-of-noncontrast-magnetic-resonance-imaging-with-diffusion-weighted-imaging-in-characterization-of-breast-lesions-intraindividual-comparison-with-dynamic-contrast-enhanced-magnetic-resonance-imaging
#9
Pascal A T Baltzer, Hubert Bickel, Claudio Spick, Georg Wengert, Ramona Woitek, Panagiotis Kapetas, Paola Clauser, Thomas H Helbich, Katja Pinker
OBJECTIVES: The aim of this study was to assess the potential of noncontrast magnetic resonance imaging (NC-MRI) with diffusion-weighted imaging (DWI) in characterization of breast lesions in comparison to dynamic contrast-enhanced MRI (DCE-MRI) at 3 T. MATERIALS AND METHODS: Consecutive patients with conventional imaging (mammography, ultrasound) BI-RADS 4/5 findings were included in this institutional review board-approved single-center study. All underwent 3 T breast MRI including readout-segmented DWI, DCE, and T2-weighted sequences...
November 22, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/29187481/pre-surgical-multiparametric-assessment-of-breast-lesions-using-3-tesla-magnetic-resonance
#10
Hynek Mirka, Radek Tupy, Andrea Narsanska, Ondrej Hes, Jiri Ferda
BACKGROUND/AIM: The aim of this study was to evaluate experience with multiparametric breast imaging on 3-Tesla magnetic resonance (3T-MRI) scanner using a dedicated 18-channel coil compared to histological findings in women after surgery. MATERIALS AND METHODS: The study included 100 women with 105 Breast Imaging Reporting and Data System (BI-RADS) 4 to 6 lesions by mammography who were examined using 3T-MRI and subsequently underwent surgery. MRI included non-contrast T1, T2 and T2 short tau inversion recovery (STIR) sequences, diffusion-weighted imaging with apparent diffusion coeficient maps, postcontrast dynamic study and single-voxel MRI spectroscopy...
December 2017: Anticancer Research
https://www.readbyqxmd.com/read/29159881/characterization-of-photon-counting-multislit-breast-tomosynthesis
#11
Karl Berggren, Björn Cederström, Mats Lundqvist, Erik Fredenberg
PURPOSE: It has been shown that breast tomosynthesis may improve sensitivity and specificity compared to two-dimensional mammography, resulting in increased detection-rate of cancers or lowered call-back rates. The purpose of this study is to characterize a spectral photon-counting multislit breast tomosynthesis system that is able to do single-scan spectral imaging with multiple collimated x-ray beams. The system differs in many aspects compared to conventional tomosynthesis using energy-integrating flat-panel detectors...
November 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/29153365/comparison-of-screening-cedm-and-mri-for-women-at-increased-risk-for-breast-cancer-a-pilot-study
#12
Maxine S Jochelson, Katja Pinker, D David Dershaw, Mary Hughes, Girard F Gibbons, Kareem Rahbar, Mark E Robson, Debra A Mangino, Debra Goldman, Chaya S Moskowitz, Elizabeth A Morris, Janice S Sung
OBJECTIVES: Contrast enhanced digital mammography (CEDM) is a new breast imaging technology increasingly used in the diagnostic setting but its utility in the pure screening setting has not been reported. The goal of this pilot study is to prospectively compare screening CEDM to breast MRI in women with an increased risk for breast cancer. METHODS: In this IRB-approved HIPAA-compliant study, 318 women at increased breast cancer risk were consented (December 2012-May 2015) to undergo CEDM in addition to their scheduled MRI...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29117707/susceptibility-of-iodine-concentration-map-of-dual-energy-contrast-enhanced-digital-mammography-for-quantitative-and-tumor-enhancement-assessment
#13
Yi-Shuan Hwang, Yun-Chung Cheung, Yu-Ying Lin, Hsiao-Lan Hsu, Hui-Yu Tsai
Background Dual-energy (DE) contrast-enhanced digital mammography (DE-CEDM) provides additional information on tumor angiogenesis. Purpose To investigate the susceptibility of reconstructing color-coded iodine concentration maps on the basis of quantitative calibrations of the iodine concentration and contrast-to-noise ratio (CNR) in DE-CEDM applications. Material and Methods A custom-made phantom filled with iodine concentrations in the range of 0.1-10 mg/cm(2) was used in calibrations. All DE images were acquired using the GE Senographe Essential system...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29107353/ultrasound-imaging-technologies-for-breast-cancer-detection-and-management-a-review
#14
REVIEW
Rongrong Guo, Guolan Lu, Binjie Qin, Baowei Fei
Ultrasound imaging is a commonly used modality for breast cancer detection and diagnosis. In this review, we summarize ultrasound imaging technologies and their clinical applications for the management of breast cancer patients. The technologies include ultrasound elastography, contrast-enhanced ultrasound, 3-D ultrasound, automatic breast ultrasound and computer-aided detection of breast ultrasound. We summarize the study results seen in the literature and discuss their future directions. We also provide a review of ultrasound-guided, breast biopsy and the fusion of ultrasound with other imaging modalities, especially magnetic resonance imaging (MRI)...
October 26, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29097928/assessing-the-risk-of-contrast-induced-nephropathy-using-a-finger-stick-analysis-in-recalls-from-breast-screening-the-cinfibs-explorative-study
#15
I P L Houben, C J L Y van Berlo, O Bekers, E C Nijssen, M B I Lobbes, J E Wildberger
Purpose: To evaluate whether a handheld point-of-care (POC) device is able to predict and discriminate patients at potential risk of contrast-induced nephropathy (CIN) prior to iodine-based contrast media delivery. Methods and Materials: Between December 2014 and June 2016, women undergoing contrast-enhanced spectral mammography (CESM) with an iodine-based contrast agent were asked to have their risk of CIN assessed by a dedicated POC device (StatSensor CREAT) and a risk factor questionnaire based on national guidelines...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29070983/application-of-bi-rads-descriptors-in-contrast-enhanced-dual-energy-mammography-comparison-with-mri
#16
Thomas Knogler, Peter Homolka, Mathias Hoernig, Robert Leithner, Georg Langs, Martin Waitzbauer, Katja Pinker, Sabine Leitner, Thomas H Helbich
BACKGROUND: Contrast-enhanced (CE) magnetic resonance imaging (MRI) BI-RADS descriptors are used in the evaluation of contrast-enhanced dual-energy mammography (CEDEM) images of mass lesions and are assumed to be applicable. PATIENTS AND METHODS: Patients with suspicious mass lesions on mammography (BI-RADS 4 or 5) were included. CEDEM examinations were performed using a modified prototype unit. CE-MRI was performed using a high temporal and high spatial resolution imaging protocol...
September 2017: Breast Care
https://www.readbyqxmd.com/read/29064748/the-future-of-contrast-enhanced-mammography
#17
Matthew F Covington, Victor J Pizzitola, Roxanne Lorans, Barbara A Pockaj, Donald W Northfelt, Catherine M Appleton, Bhavika K Patel
OBJECTIVE: The purpose of this article is to discuss facilitators of and barriers to future implementation of contrast-enhanced mammography (CEM) in the United States. CONCLUSION: CEM provides low-energy 2D mammographic images analogous to digital mammography and contrast-enhanced recombined images that allow assessment of neovascularity similar to that offered by MRI. The utilization of CEM in the United States is currently low but could increase rapidly given the many potential indications for its clinical use...
October 24, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29058963/contrast-enhanced-spectral-mammography-in-patients-with-mri-contraindications
#18
Vivien Richter, Valerie Hatterman, Heike Preibsch, Sonja D Bahrs, Markus Hahn, Konstantin Nikolaou, Benjamin Wiesinger
Background Contrast-enhanced spectral mammography (CESM) is a novel breast imaging technique providing comparable diagnostic accuracy to breast magnetic resonance imaging (MRI). Purpose To show that CESM in patients with MRI contraindications is feasible, accurate, and useful as a problem-solving tool, and to highlight its limitations. Material and Methods A total of 118 patients with MRI contraindications were examined by CESM. Histology was obtained in 94 lesions and used as gold standard for diagnostic accuracy calculations...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28987661/contamination-artifact-that-mimics-in-situ-carcinoma-on-contrast-enhanced-digital-mammography
#19
Jill Gluskin, Michael Click, Richard Fleischman, Clarisse Dromain, Elizabeth A Morris, Maxine S Jochelson
PURPOSE: Contrast-enhanced digital mammography (CEDM) is an advanced breast imaging technique using iodinated intravenous contrast to detect breast cancer. This article describes imaging features of a skin contamination artifact on CEDM that mimics in-situ carcinoma in a case series. MATERIALS AND METHODS: Five patients were identified whose CEDM images demonstrated apparent calcifications and non-mass enhancement suspicious for in-situ carcinoma, with no subsequent evidence of disease...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28982628/first-in-human-study-of-acoustic-angiography-in-the-breast-and-peripheral-vasculature
#20
Sarah E Shelton, Brooks D Lindsey, Paul A Dayton, Yueh Z Lee
Screening with mammography has been found to increase breast cancer survival rates by about 20%. However, the current system in which mammography is used to direct patients toward biopsy or surgical excision also results in relatively high rates of unnecessary biopsy, as 66.8% of biopsies are benign. A non-ionizing radiation imaging approach with increased specificity might reduce the rate of unnecessary biopsies. Quantifying the vascular characteristics within and surrounding lesions represents one potential target for assessing likelihood of malignancy via imaging...
October 2, 2017: Ultrasound in Medicine & Biology
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