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Contrast enhanced mammography

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https://www.readbyqxmd.com/read/28055247/-staging-of-breast-cancer-and-the-advanced-applications-of-digital-mammogram-what-the-physician-needs-to-know
#1
Maha Hussien Helal, Sahar Mahmoud Mansour, Mai Zaglol, Lamia Adel Salaleldin, Omniya Mokhtar Nada, Marwa Anas Haggag
OBJECTIVE: To study the role of advanced applications of digital mammogram whether contrast enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT) in the "T" staging of histologically proven breast cancer prior management planning. METHODS: This prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and presence of associated clusters of microcalcifications. Evaluation methods included digital mammography, 3-D tomosynthesis and contrast enhanced spectral mammography...
January 5, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28047752/we-de-207b-04-quantitative-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors-a-feasibility-study
#2
H Ding, B Zhou, D Beidokhti, S Molloi
PURPOSE: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. METHODS: Experimental phantom studies were performed on a spectral mammography system based on Si strip photon-counting detectors. Dual-energy images were acquired using 40 kVp and a splitting energy of 34 keV with 3 mm Al pre-filtration. The initial calibration was done with glandular and adipose tissue equivalent phantoms of uniform thicknesses and iodine disk phantoms of various concentrations...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047365/mo-fg-campus-iep1-01-alternative-k-edge-filters-for-low-energy-image-acquisition-in-contrast-enhanced-spectral-mammography
#3
S Shrestha, S Vedantham, A Karellas
PURPOSE: In Contrast Enhanced Spectral Mammography (CESM), Rh filter is often used during low-energy image acquisition. The potential for using Ag, In and Sn filters, which exhibit K-edge closer to, and just below that of Iodine, instead of the Rh filter, was investigated for the low-energy image acquisition. METHODS: Analytical computations of the half-value thickness (HVT) and the photon fluence per mAs (photons/mm2/mAs) for 50µm Rh were compared with other potential K-edge filters (Ag, In and Sn), all with K-absorption edge below that of Iodine...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046981/we-de-207b-01-optimization-for-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors
#4
H Ding, S Molloi
PURPOSE: To investigate the feasibility of optimizing the imaging parameters for contrast-enhanced spectral mammography based on Si strip photon-counting detectors. METHODS: A computer simulation model using polyenergetic spectra from a tungsten anode x-ray tube and a Si-based photon-counting detector was evaluated for contrast-enhanced spectral mammography. The simulation traces the emission of photons from the x-ray source, attenuation through the breast and subsequent absorption in the detector...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046698/mo-fg-campus-iep1-02-dose-reduction-in-contrast-enhanced-digital-mammography-using-a-photon-counting-detector
#5
S Lee, S Kang, J Eom
PURPOSE: Photon-counting detectors (PCDs) allow multi-energy X-ray imaging without additional exposures and spectral overlap. This capability results in the improvement of accuracy of material decomposition for dual-energy X-ray imaging and the reduction of radiation dose. In this study, the PCD-based contrast-enhanced dual-energy mammography (CEDM) was compared with the conventional CDEM in terms of radiation dose, image quality and accuracy of material decomposition. METHODS: A dual-energy model was designed by using Beer-Lambert's law and rational inverse fitting function for decomposing materials from a polychromatic X-ray source...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044312/optimization-of-contrast-enhanced-breast-imaging-analysis-using-a-cascaded-linear-system-model
#6
Yue-Houng Hu, David A Scaduto, Wei Zhao
PURPOSE: Contrast-enhanced (CE) breast imaging involves the injection contrast agents (i.e., iodine) to increase conspicuity of malignant lesions. CE imaging may be used in conjunction with digital mammography (DM) or digital breast tomosynthesis (DBT) and has shown promise in improving diagnostic specificity. Both CE-DM and CE-DBT techniques require optimization as clinical diagnostic tools. Physical factors including x-ray spectra, subtraction technique, and the signal from iodine contrast, must be considered to provide the greatest object detectability and image quality...
November 21, 2016: Medical Physics
https://www.readbyqxmd.com/read/27981485/-1-h-mr-spectroscopy-of-suspicious-breast-mass-lesions-at-3t-a-clinical-experience
#7
Stefania Montemezzi, Carlo Cavedon, Lucia Camera, Gabriele Meliadò, Francesca Caumo, Ilaria Baglio, Francesco Sardanelli
OBJECTIVES: To test 3T proton magnetic resonance spectroscopy ((1)H-MRS) for breast mass lesions. METHODS: Patients with BI-RADS 4-5 lesions at mammography/ultrasound were prospectively enrolled. After contrast-enhanced breast MRI, single-voxel MRS (point-resolved volume selection, PRESS); pencil-beam shimming; volume of interest 1 cm(3); TR/TE = 3000/135 ms) was performed. Spectra were considered reliable if the full width at half maximum (FWHM) of the water peak was ≤45 Hz...
December 15, 2016: La Radiologia Medica
https://www.readbyqxmd.com/read/27955878/prevalence-and-predictive-value-of-bi-rads-3-4-and-5-lesions-detected-on-breast-mri-correlation-with-study-indication
#8
Sona A Chikarmane, Ryan Tai, Jack E Meyer, Catherine S Giess
RATIONALE AND OBJECTIVES: This study aims to determine the prevalence and predictive value of Breast Imaging Reporting and Data System (BI-RADS) 3, 4, and 5 findings on breast magnetic resonance imaging (MRI) and to evaluate the impact of study indication on the predictive value of BI-RADS categories. MATERIALS AND METHODS: This institutional review board approved, Health Insurance Portability and Accountability Act (HIPAA) compliant retrospective review of our breast MRI database from 2009 to 2011, of 5778 contrast-enhanced studies in 3360 patients was performed...
December 7, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27901596/magnetic-resonance-imaging-in-the-pre-surgical-staging-of-breast-cancer-our-experience
#9
Paola Rabasco, Rocchina Caivano, Giuseppina Dinardo, Matilde Gioioso, Antonella Lotumolo, Giancarlo Iannelli, Antonio Villonio, Giuseppe La Torre, Stefano D'Errico, Luca Macarini, Giuseppe Guglielmi, Aldo Cammarota
PURPOSE: To investigate the clinical impact of magnetic resonance imaging (MRI) in the detection of multifocal-multicentric breast cancers, already identified by mammography and ultrasound, and analyzed histologically, to evaluate its role in preoperative staging. MATERIALS AND METHODS: From January 2012 to February 2014, 188 patients, aged 28 to 74 years, newly diagnosed with breast cancer on conventional imaging (mammography and ultrasound) were enrolled. They underwent preoperative contrast-enhanced 3T MRI...
November 30, 2016: Cancer Investigation
https://www.readbyqxmd.com/read/27896471/contrast-enhanced-spectral-mammography-vs-mammography-and-mri-clinical-performance-in-a-multi-reader-evaluation
#10
Eva M Fallenberg, Florian F Schmitzberger, Heba Amer, Barbara Ingold-Heppner, Corinne Balleyguier, Felix Diekmann, Florian Engelken, Ritse M Mann, Diane M Renz, Ulrich Bick, Bernd Hamm, Clarisse Dromain
OBJECTIVES: To compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) to digital mammography (MG) and magnetic resonance imaging (MRI) in a prospective two-centre, multi-reader study. METHODS: One hundred seventy-eight women (mean age 53 years) with invasive breast cancer and/or DCIS were included after ethics board approval. MG, CESM and CESM + MG were evaluated by three blinded radiologists based on amended ACR BI-RADS criteria...
November 28, 2016: European Radiology
https://www.readbyqxmd.com/read/27875762/review-of-clinical-studies-and-first-clinical-experiences-with-a-commercially-available-cone-beam-breast-ct-in-europe
#11
REVIEW
Susanne Wienbeck, Joachim Lotz, Uwe Fischer
The dedicated cone-beam breast computed tomography (CBBCT) is a new and promising imaging modality which provides isotropic, 3D images of the breast with high spatial and contrast resolution. Non-contrast and contrast-enhanced CBBCT (CE-CBBCT) was superior to mammography for the visualization of breast masses, especially in patients with dense breast tissue. CE-CBBCT accurately detects DCIS and distinguishes it from benign causes of microcalcifications when compared with non-contrast CBBCT and mammography. The purpose of this report is to describe the technology and its possible indications, and to present the first results from recent clinical studies, illustrating these with our own image examples...
November 17, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/27854006/mammography-an-update-of-the-eusobi-recommendations-on-information-for-women
#12
Francesco Sardanelli, Eva M Fallenberg, Paola Clauser, Rubina M Trimboli, Julia Camps-Herrero, Thomas H Helbich, Gabor Forrai
: This article summarises the information to be offered to women about mammography. After a delineation of the aim of early diagnosis of breast cancer, the difference between screening mammography and diagnostic mammography is explained. The need to bring images and reports from the previous mammogram (and from other recent breast imaging examinations) is highlighted. Mammography technique and procedure are described with particular attention to discomfort and pain experienced by a small number of women who undergo the test...
November 16, 2016: Insights Into Imaging
https://www.readbyqxmd.com/read/27853497/imaging-findings-in-patients-with-granulomatous-mastitis
#13
Pelin Seher Oztekin, Gamze Durhan, Pinar Nercis Kosar, Serap Erel, Sema Hucumenoglu
BACKGROUND: Granulomatous mastitis (GM) is a rare inflammatory breast disease that may mimic the clinical characteristics and radiologic imaging findings of breast carcinoma. Considering the importance of making a correct diagnosis, careful radiologic evaluations and recognition of imaging features are necessary. OBJECTIVES: The aim of this study was to review the radiological findings and diagnostic value of the imaging in GM. PATIENTS AND METHODS: This retrospective study involved a total of 29 patients who were diagnosed with GM between 2009 and 2013 and who underwent mammography (MG) and/or ultrasound (US) examination in addition to magnetic resonance imaging (MRI) before diagnosis...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27853496/a-case-of-a-concurrent-and-co-located-invasive-carcinoma-and-a-fibroadenoma-to-illustrate-the-potential-of-dual-energy-contrast-enhanced-digital-mammography-on-the-diagnosis-of-complex-breast-lesions
#14
Maria Del Mar Travieso Aja, Purificacion Munoz, Mario Rodriguez Rodriguez, Victor Vega Benitez, Octavio P Luzardo
Up to 19% of breast malignancies may be missed by conventional imaging techniques, especially when they are concurrent or co-located with other benign lesions. However, more sensitive techniques, such as magnetic resonance imaging (MRI), are often too expensive for routine use in developing countries. Contrast-enhanced, dual-energy digital mammography (CESM) is a recently introduced imaging modality whose performance has been reported to be similar to that of MRI. Being much cheaper, CESM may constitute a good alternative for improving diagnostic sensitivity in these countries...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27842678/diagnostic-efficacy-and-safety-of-gadoteric-acid-mr-mammography-in-1537-patients
#15
Tim Seithe, Joachim Braun, Michael Wolf, Janis Vahldiek, Dajana Wolny, Jonas Auer, Joanna Pociej, Oliver Heine, Bernd Hamm, Maximilian de Bucourt
OBJECTIVES: To perform a large-scale multicenter post-marketing surveillance study for analyzing diagnostic effectiveness and safety of intravenous (IV) gadoteric acid (Dotarem(®)) in magnetic resonance (MR) mammography under daily practice conditions. MATERIALS AND METHODS: Patients underwent high-resolution MR mammography with gadoteric acid in 15 German centers. Radiologists used a standardized questionnaire to report data including patient demographics and medical history, characteristics of MR examination and results in terms of diagnosis and safety for the patient...
December 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27788035/mr-imaging-for-diagnosis-of-malignancy-in-mammographic-microcalcifications-a-systematic-review-and-meta-analysis
#16
Barbara Bennani-Baiti, Pascal A Baltzer
Purpose To assess the use of magnetic resonance (MR) imaging for diagnosis of malignancy in lesions that manifest as microcalcifications at mammography. Materials and Methods Two independent readers performed a systematic review of the literature published as of February 1, 2016, by using predefined search terms. All studies in which contrast material-enhanced MR imaging was used for assessment of mammographic microcalcifications that were assigned Breast Imaging Reporting and Data System (BI-RADS) scores of 3-5 were deemed eligible...
October 27, 2016: Radiology
https://www.readbyqxmd.com/read/27773458/contrast-enhanced-spectral-mammography-technique-indications-and-clinical-applications
#17
Chandni Bhimani, Danielle Matta, Robyn G Roth, Lydia Liao, Elizabeth Tinney, Kristin Brill, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) combines the benefits of full field digital mammography with the concept of tumor angiogenesis. Technique and practical applications of CESM are discussed. MATERIALS AND METHODS: An overview of the technique is followed by a demonstration of practical applications of CESM in our practice. RESULTS: We have successfully implemented CESM into our practice as a screening, diagnostic, staging, and treatment response tool...
January 2017: Academic Radiology
https://www.readbyqxmd.com/read/27768681/degree-of-enhancement-on-contrast-enhanced-spectral-mammography-cesm-and-lesion-type-on-mammography-mg-comparison-based-on-histological-results
#18
Elżbieta Łuczyńska, Joanna Niemiec, Edward Hendrick, Sylwia Heinze, Janusz Jaszczyński, Jerzy Jakubowicz, Beata Sas-Korczyńska, Janusz Rys
BACKGROUND Contrast enhanced spectral mammography (CESM) is a new method of breast cancer diagnosis in which an iodinated contrast agent is injected and dual-energy mammography is obtained in multiple views of the breasts. The aim of this study was to compare the degree of enhancement on CESM with lesion characteristics on mammography (MG) and lesion histology in women with suspicious breast lesions. MATERIAL AND METHODS The degree of enhancement on CESM (absent, weak, medium, or strong) was compared to lesion characteristics on MG (mass, mass with microcalcifications, or microcalcifications alone) and histology (infiltrating carcinoma, intraductal carcinoma, or benign) to compare sensitivity of the two modalities and to establish correlations that might improve diagnostic accuracy...
October 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27765597/contrast-enhanced-spectral-mammography-modality-specific-artifacts-and-other-factors-which-may-interfere-with-image-quality
#19
Chandni Bhimani, Luna Li, Lydia Liao, Robyn G Roth, Elizabeth Tinney, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) uses full field digital mammography with the added benefit of intravenous contrast administration to significantly reduce false-positive and false-negative results and improve specificity while maintaining high sensitivity. For CESM to fulfill its purpose, one should be aware of possible artifacts and other factors which may interfere with image quality, and attention should be taken to minimize these factors. MATERIALS AND METHODS: This pictorial demonstration will depict types of artifacts detected and other factors that interfere with image acquisition in our practice since CESM implementation...
January 2017: Academic Radiology
https://www.readbyqxmd.com/read/27727117/cone-beam-micro-computed-tomography-dedicated-to-the-breast
#20
Antonio Sarno, Giovanni Mettivier, Francesca Di Lillo, Mario Cesarelli, Paolo Bifulco, Paolo Russo
We developed a scanner for micro computed tomography dedicated to the breast (BµCT) with a high resolution flat-panel detector and a microfocus X-ray tube. We evaluated the system spatial resolution via the 3D modulation transfer function (MTF). In addition to conventional absorption-based X-ray imaging, such a prototype showed capabilities for propagation-based phase-contrast and related edge enhancement effects in 3D imaging. The system limiting spatial resolution is 6.2mm(-1) (MTF at 10%) in the vertical direction and 3...
October 7, 2016: Medical Engineering & Physics
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