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Contrast enhanced mammography

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https://www.readbyqxmd.com/read/28935459/clinical-and-pathologic-features-of-clinically-occult-synchronous-bilateral-breast-cancers
#1
Lumarie Santiago, Gary Whitman, Cuiyan Wang, Basak E Dogan
PURPOSE: To investigate clinicopathologic breast cancer characteristics associated with the identification of synchronous bilateral breast cancer (SBBC) on dynamic contrast-enhanced breast magnetic resonance imaging. METHODS: We performed a retrospective review of 311 consecutive patients newly diagnosed with breast cancer who underwent diagnostic mammography, ultrasonography, and dynamic contrast-enhanced breast magnetic resonance imaging (DCE-MRI) at our institution...
August 24, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28894329/accuracy-of-contrast-enhanced-spectral-mammography-for-estimating-residual-tumor-size-after-neoadjuvant-chemotherapy-in-patients-with-breast-cancer-a-feasibility-study
#2
Filipe Ramos Barra, Fernanda Freire de Souza, Rosimara Eva Ferreira Almeida Camelo, Andrea Campos de Oliveira Ribeiro, Luciano Farage
OBJECTIVE: To assess the feasibility of contrast-enhanced spectral mammography (CESM) of the breast for assessing the size of residual tumors after neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS: In breast cancer patients who underwent NAC between 2011 and 2013, we evaluated residual tumor measurements obtained with CESM and full-field digital mammography (FFDM). We determined the concordance between the methods, as well as their level of agreement with the pathology...
July 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28893303/contrast-enhanced-spectral-mammography-in-neoadjuvant-chemotherapy-monitoring-a-comparison-with-breast-magnetic-resonance-imaging
#3
Valentina Iotti, Sara Ravaioli, Rita Vacondio, Chiara Coriani, Sabrina Caffarri, Roberto Sghedoni, Andrea Nitrosi, Moira Ragazzi, Elisa Gasparini, Cristina Masini, Giancarlo Bisagni, Giuseppe Falco, Guglielmo Ferrari, Luca Braglia, Alberto Del Prato, Ivana Malavolti, Vladimiro Ginocchi, Pierpaolo Pattacini
BACKGROUND: Neoadjuvant-chemotherapy (NAC) is considered the standard treatment for locally advanced breast carcinomas. Accurate assessment of disease response is fundamental to increase the chances of successful breast-conserving surgery and to avoid local recurrence. The purpose of this study was to compare contrast-enhanced spectral mammography (CESM) and contrast-enhanced-MRI (MRI) in the evaluation of tumor response to NAC. METHODS: This prospective study was approved by the institutional review board and written informed consent was obtained...
September 11, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28870431/could-parenchymal-enhancement-on-contrast-enhanced-spectral-mammography-cesm-represent-a-new-breast-cancer-risk-factor-correlation-with-known-radiology-risk-factors
#4
S L Savaridas, D B Taylor, D Gunawardana, M Phillips
AIM: To compare background parenchymal enhancement (BPE) on contrast-enhanced (CE) spectral mammography (CESM) with CE magnetic resonance imaging (MRI), and evaluate how these relate to hormonal status, mammographic breast density (MBD) and MRI fibroglandular tissue volume (FGTV). METHODS AND MATERIALS: Between June 2012 to October 2015, participants in a cancer staging study underwent full-field digital mammography (FFDM), CEMRI, and CESM. Two readers independently rated FGTV, MBD, and BPE using the Breast Imaging-Reporting and Data System (BI-RADS) criteria...
September 1, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28783629/low-dose-contrast-enhanced-breast-ct-using-spectral-shaping-filters-an-experimental-study
#5
Andrey Makeev, Stephen J Glick
Iodinated contrast-enhanced x-ray imaging of the breast has been studied with various modalities including, fullfield digital mammography (FFDM), digital breast tomosynthesis (DBT), and dedicated breast CT (BCT). Contrast imaging with breast CT has a number of advantages over FFDM and DBT including the lack of breast compression, and generation of fully isotropic, three-dimensional reconstructions. Nonetheless, for breast CT to be considered as a viable tool for routine clinical use, it would be desirable to reduce radiation dose...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28781820/rare-imaging-appearance-of-adenoid-cystic-carcinoma-of-the-breast-a-case-report
#6
Hongli Wang, Fengtao Liu, Ran Gu, Yong Li, Fengxi Su
Adenoid cystic carcinoma (ACC) of the breast is a rare tumor comprising <0.1% of all breast malignancies. The present study reports the case of a 66-year-old woman who underwent multiple imaging techniques, including mammography, ultrasonography and magnetic resonance imaging (MRI). The patient reported gradual enlargement of a mass in the left breast. Mammography identified a high-density, irregular mass, with nipple retraction. Ultrasonography revealed an irregular, complex cystic and solid mass with an unclear margin in the subareolar region...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28780840/-diagnostic-value-of-quantitative-pharmacokinetic-parameters-and-relative-quantitative-pharmacokinetic-parameters-in-breast-lesions-with-dynamic-contrast-enhanced-mri
#7
T T Sun, W H Liu, Y Q Zhang, L H Li, R Wang, Y Y Ye
Objective: To explore the differential between the value of dynamic contrast-enhanced MRI quantitative pharmacokinetic parameters and relative pharmacokinetic quantitative parameters in breast lesions. Methods: Retrospective analysis of 255 patients(262 breast lesions) who was obtained by clinical palpation , ultrasound or full-field digital mammography , and then all lessions were pathologically confirmed in Zhongda Hospital, Southeast University from May 2012 to May 2016. A 3.0 T MRI scanner was used to obtain the quantitative MR pharmacokinetic parameters: volume transfer constant (K(trans)), exchange rate constant (k(ep))and extravascular extracellular volume fraction (V(e))...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28750354/assessing-tumor-extent-on-contrast-enhanced-spectral-mammography-versus-full-field-digital-mammography-and-ultrasound
#8
Bhavika K Patel, Sandra Alheli Garza, Sarah Eversman, Yania Lopez-Alvarez, Heidi Kosiorek, Barbara A Pockaj
OBJECTIVES: To compare breast cancer size measurements on full-field digital mammography (FFDM), contrast-enhanced spectral mammography (CEDM), and ultrasound (US), with histologic tumor size used as the reference standard. Material and methods The HIPAA complaint, IRB approved study comprised 88 women with newly diagnosed breast cancer who underwent FFDM and CEDM;74 also had US. Breast density, histologic subtype, and maximum tumor measurements were recorded. RESULTS: Pearson correlation coefficients for FFDM, US, and CEDM vs histopathology were 0...
July 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28740447/breast-dynamic-contrast-enhanced-mri-fibrocystic-changes-presenting-as-a-non-mass-enhancement-mimicking-malignancy
#9
Zorica C Milosevic, Mirjan M Nadrljanski, Zorka M Milovanovic, Nina Z Gusic, Slavko S Vucicevic, Olga S Radulovic
BACKGROUND: We aimed to analyse the morphokinetic features of breast fibrocystic changes (nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia) presenting as a non-mass enhancement (NME)in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) examination. PATIENTS AND METHODS: Forty-six patients with histologically proven fibrocystic changes (FCCs) were retrospectively reviewed, according to Breast Imaging Reporting and Data System (BI-RADS) lexicon...
June 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28723585/clinical-utility-of-contrast-enhanced-spectral-mammography-as-an-adjunct-for-tomosynthesis-detected-architectural-distortion
#10
Bhavika K Patel, Michelle E Naylor, Heidi E Kosiorek, Yania M Lopez-Alvarez, Adrian M Miller, Victor J Pizzitola, Barbara A Pockaj
OBJECTIVE: Supplement tomosynthesis-detected architectural distortions (AD) with CESM to better characterize malignant vs benign lesions. METHODS: Retrospective review CESM prior to biopsied AD. Pathology: benign, radial scar, or malignant. RESULTS: 49 lesions (45 patients). 29 invasive cancers, 1 DCIS (range, 0.4-4.7cm); 9 radial scars; 10 benign. 37 (75.5%) ADs had associated enhancement. PPV 78.4% (29/37), sensitivity 96.7% (29/30); specificity, 57...
July 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28688583/image-improvement-method-for-positron-emission-mammography
#11
Nikolai V Slavine, Stephen J Seiler, Roderick W McColl, Robert E Lenkinski
PURPOSE: To evaluate in clinical use a rapidly converging, efficient iterative deconvolution algorithm (RSEMD) for improving the quantitative accuracy of previously reconstructed breast images by a commercial positron emission mammography (PEM) scanner. MATERIALS AND METHODS: The RSEMD method was tested on imaging data from clinical Naviscan Flex Solo II PEM scanner. This method was applied to anthropomorphic like breast phantom data and patient breast images previously reconstructed with Naviscan software to determine improvements in image resolution, signal to noise ratio (SNR) and contrast to noise ratio (CNR)...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28681390/a-deep-feature-fusion-methodology-for-breast-cancer-diagnosis-demonstrated-on-three-imaging-modality-datasets
#12
Natalia Antropova, Benjamin Q Huynh, Maryellen L Giger
Deep learning methods for radiomics/computer-aided diagnosis (CADx) are often prohibited by small datasets, long computation time, and the need for extensive image preprocessing. We present a methodology that extracts and pools low- to mid-level features using a pre-trained convolutional neural network and fuses them with handcrafted radiomic features computed using conventional CADx methods. Our fusion-based method demonstrates significant improvements to previous breast cancer CADx methods across three clinical imaging modalities (dynamic contrast-enhanced MRI, full-field digital mammography, and ultrasound) in terms of predictive performance in the task of estimating lesion malignancy...
July 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28656455/malignancy-detection-on-mammography-using-dual-deep-convolutional-neural-networks-and-genetically-discovered-false-color-input-enhancement
#13
Philip Teare, Michael Fishman, Oshra Benzaquen, Eyal Toledano, Eldad Elnekave
Breast cancer is the most prevalent malignancy in the US and the third highest cause of cancer-related mortality worldwide. Regular mammography screening has been attributed with doubling the rate of early cancer detection over the past three decades, yet estimates of mammographic accuracy in the hands of experienced radiologists remain suboptimal with sensitivity ranging from 62 to 87% and specificity from 75 to 91%. Advances in machine learning (ML) in recent years have demonstrated capabilities of image analysis which often surpass those of human observers...
August 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28654337/newly-diagnosed-breast-cancer-comparison-of-contrast-enhanced-spectral-mammography-and-breast-mr-imaging-in-the-evaluation-of-extent-of-disease
#14
Stephanie A Lee-Felker, Leena Tekchandani, Mariam Thomas, Esha Gupta, Denise Andrews-Tang, Antoinette Roth, James Sayre, Guita Rahbar
Purpose To compare the diagnostic performances of contrast material-enhanced spectral mammography and breast magnetic resonance (MR) imaging in the detection of index and secondary cancers in women with newly diagnosed breast cancer by using histologic or imaging follow-up as the standard of reference. Materials and Methods This institutional review board-approved, HIPAA-compliant, retrospective study included 52 women who underwent breast MR imaging and contrast-enhanced spectral mammography for newly diagnosed unilateral breast cancer between March 2014 and October 2015...
June 26, 2017: Radiology
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#15
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
June 13, 2017: Radiology
https://www.readbyqxmd.com/read/28583631/repeated-surgeries-in-invasive-lobular-breast-cancer-with-preoperative-mri-role-of-additional-carcinoma-in-situ-and-background-parenchymal-enhancement
#16
H Preibsch, V Richter, S D Bahrs, V Hattermann, B M Wietek, G Bier, C Kloth, G Blumenstock, M Hahn, A Staebler, K Nikolaou, B Wiesinger
OBJECTIVES: Analysing the influence of additional carcinoma in situ (CIS) and background parenchymal enhancement (BPE) in preoperative MRI on repeated surgeries in patients with invasive lobular carcinoma (ILC) of the breast. METHODS: Retrospective analysis of 106 patients (mean age 58.6±9.9years) with 108 ILC. Preoperative tumour size as assessed by MRI, mammography and sonography was recorded and compared to histopathology. In contrast-enhanced MRI, the degree of BPE was categorised by two readers...
May 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28549292/globally-supported-radial-basis-function-based-collocation-method-for-evolution-of-level-set-in-mass-segmentation-using-mammograms
#17
Kanchan Lata Kashyap, Manish Kumar Bajpai, Pritee Khanna
Computer-aided detection systems play an important role for the detection of breast abnormalities using mammograms. Global segmentation of mass in mammograms is a complex process due to low contrast mammogram images, irregular shape of mass, speculated margins, and the presence of intensity variations of pixels. This work presents a new approach for mass detection in mammograms, which is based on the variational level set function. Mesh-free based radial basis function (RBF) collocation approach is employed for the evolution of level set function for segmentation of breast as well as suspicious mass region...
August 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28543761/experimental-characterization-of-a-direct-conversion-amorphous-selenium-detector-with-thicker-conversion-layer-for-dual-energy-contrast-enhanced-breast-imaging
#18
David A Scaduto, Olivier Tousignant, Wei Zhao
PURPOSE: Dual-energy contrast-enhanced imaging is being investigated as a tool to identify and localize angiogenesis in the breast, a possible indicator of malignant tumors. This imaging technique requires that x-ray images are acquired at energies above the k-shell binding energy of an appropriate radiocontrast agent. Iodinated contrast agents are commonly used for vascular imaging, and require x-ray energies greater than 33 keV. Conventional direct conversion amorphous selenium (a-Se) flat-panel imagers for digital mammography show suboptimal absorption efficiencies at these higher energies...
August 2017: Medical Physics
https://www.readbyqxmd.com/read/28541197/high-energy-resolution-hyperspectral-x-ray-imaging-for-low-dose-contrast-enhanced-digital-mammography
#19
Silvia Pani, Sarene C Saifuddin, Filipa I M Ferreira, Nicholas Henthorn, Paul Seller, Paul J Sellin, Philipp Stratmann, Matthew C Veale, Matthew D Wilson, Robert J Cernik
Contrast-enhanced digital mammography (CEDM) is an alternative to conventional X-ray mammography for imaging dense breasts. However, conventional approaches to CEDM require a double exposure of the patient, implying higher dose, and risk of incorrect image registration due to motion artifacts. A novel approach is presented, based on hyperspectral imaging, where a detector combining positional and high-resolution spectral information (in this case based on Cadmium Telluride) is used. This allows simultaneous acquisition of the two images required for CEDM...
September 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28457521/image-processing-can-cause-some-malignant-soft-tissue-lesions-to-be-missed-in-digital-mammography-images
#20
L M Warren, M D Halling-Brown, P T Looney, D R Dance, M G Wallis, R M Given-Wilson, L Wilkinson, R McAvinchey, K C Young
AIM: To investigate the effect of image processing on cancer detection in mammography. METHODS AND MATERIALS: An observer study was performed using 349 digital mammography images of women with normal breasts, calcification clusters, or soft-tissue lesions including 191 subtle cancers. Images underwent two types of processing: FlavourA (standard) and FlavourB (added enhancement). Six observers located features in the breast they suspected to be cancerous (4,188 observations)...
September 2017: Clinical Radiology
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